Дисертації з теми "Endoprothèse vasculaire"
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Turjman, Francis. "Étude expérimentale du traitement des anévrysmes par endoprothèse vasculaire." Lyon 1, 1994. http://www.theses.fr/1994LYO1T191.
M'Bengue, Marie-Stella. "Conception et évaluation d'une endoprothèse vasculaire par impression 3D pour le traitement des anévrismes complexes de l'aorte abdominale." Electronic Thesis or Diss., Université de Lille (2022-....), 2022. http://www.theses.fr/2022ULILS057.
Endovascular repair (EVAR) of an abdominal aortic aneurysm (AAA) involves the placement into the aneurysm of a stent graft (SG) by minimally invasive surgery. This procedure prevents rupture of the damaged tissue involved in an AAA, defined as a localized diameter dilation of the aorta. When the upstream portion of the aneurysm includes the peripheral renal and/or visceral arteries, the AAA is qualified as complex. In this case, the deployed SG is said “fenestrated”, in other words, perforated at the site of junctions to the peripheral arteries. Management of a complex AAA becomes more limiting as the fenestrated SG will be custom designed to match the anatomy of the aneurysm and the position of the peripheral arteries of the patient. This implies a manufacturing delay of several weeks, limits the management to stable aneurysms and excludes emergency situations. In this context, 3D printing (3DP) is of considerable interest for the fabrication of custom-made SGs in a very short time frame. Thus, the objective of this thesis work is to design a SG prototype by 3D printing of a medical grade thermoplastic polyurethane (TPU) (thermoplastic elastomer). The present work will validate the manufacturing process and the functionality of our 3DP-SG for its final application as an implantable medical device.First, the impact of the manufacturing process on the chemical, physical and physicochemical properties of TPU was studied at each step, from the pellets to the gamma-ray sterilization of a graft manufactured by fused filament deposition (FDM). In vitro preliminary evaluation of the cytotoxicity and hemocompatibility of TPU was carried out after the 3D printing and sterilization step. Aging of TPU under extreme oxidizing conditions was performed to predict the evolution of its properties in the long term. Subsequently, a design strategy for an endovascular implantable prototype was developed. The properties of said prototype were characterized by different techniques (SEC, TGA, DSC, FTIR, SEM, goniometry, uniaxial traction, ...). Its biological properties were evaluated in vitro by tests of cytocompatibility, hemocompatibility and contact with macrophages for 24 hours (acute inflammation). Moreover, the evolution of its physicochemical and mechanical properties was evaluated by in vitro aging studies.The characterization of the chemical, physical and physicochemical properties of TPU enabled the validation of a FDM printing manufacturing route and gamma ray sterilization of a crimpable SG prototype. The in vitro biological evaluation showed the non-cytotoxicity of the SG prototype by the extraction method. Moreover, the prototype was found to be weakly hemolytic and the platelets adhered on its surface were not activated. The low secretion of cytokines (IL-6 and TNF-α) upon contact with inactivated macrophages showed that the SG prototype does not exhibit a pro-inflammatory characteristic. Finally, aging studies showed an impact on the mechanical and surface properties of our SG prototype without compromising its functionality. Subsequently, the design strategy could evolve towards a functionalization of the SG prototype in order to prevent infections and thrombosis responsible for 2% and 6% of postoperative complications respectively
Ott, Franck. "Développement et optimisation d'endoprothèses vasculaires." Thesis, Université Grenoble Alpes (ComUE), 2019. http://www.theses.fr/2019GREAI019.
Abdominal aortic aneurysm (AAA) is a pathology that must be repaired by a surgical procedure to avoid a rupture, lethal in most of the cases. Endovascular aneurysm repair (EVAR) is a non-invasive procedure, allowing the deployment of a stent-graft inside the aneurysmal sac. Nevertheless, clinical feedback currently available for stent-grafts show that many complications after surgery – migrations, thrombosis, endoleaks, rupture – are closely linked to the mechanical behaviour of the stent-grafts, which is heterogeneous and very far from the one of the aorta. This behaviour is induced by the design of current stent-grafts, made by assembling a textile body with an exoskeleton sutured on the latter. These post-operative problems frequently lead to a second operation of the patient, which drastically reduces the benefits of endovascular surgery.In-vivo, stent-grafts are submitted to various loadings: inflation induced by the blood pressure, compression due to surrounding organs, but also bending due to the patient motion or the aorta tortuosity, etc. As far as possible, the mechanical behaviour of stent-grafts must also be as closed as possible to the original aorta, to avoid mechanical discontinuities that may be responsible for intimal hyperplasia.In this context, the principal purpose of this thesis is to contribute to the development and the optimization of vascular endoprostheses, resulting from an innovative manufacturing technology whose target is to insert a helical metallic wire in NiTi within a knitted PET textile body. This technology allows to build homogeneous textile tubes without any exo-skeleton. In order to optimize these structures, various experimental tests coupled with 2D or 3D imaging techniques – Synchrotron and laboratory X-ray micro-tomography – have been developed to characterize the mechanical behavior as well as permeability of these tubes. The results of these different tests are compared to experimental or numerical results of the literature regarding the native aortic tissue, as well as data concerning market products. The ultimate goal of this work is to provide new stent-grafts whose behavior is close to the native abdominal aorta, and which limit current post-operative problems
Dumoulin, Christine. "Analyse et modélisation de comportements mécaniques des endoprothèses." Aix-Marseille 2, 2000. http://www.theses.fr/2000AIX22093.
Ivanenko, Andrei. "Contribution à l'étude du comportement mécanique des prothèses et endoprothèses vasculaires." Mulhouse, 2008. http://www.theses.fr/2008MULH0906.
Every day the vascular textiles prostheses save lives. However, some localized ruptures were reported. In our laboratory, we have been characterising the polymer (polyéthylene téréphtalate) from which the vascular textile prostheses are made. We have been studying the organizations and the degradations of macromolecular chains. However, the organization of polymer and its physical aging depends on mechanical state of stress. Thus this thesis work was intended to provide new knowledge about the mechanical behaviour of textile structures and filaments. Given the fast that the standard mechanical tests are not representative, as to say, destructive and have little relation to physiological reality, we chose to develop a tear testing method with sinusoidal modulation of elongation. This method is coupled with monitoring the structural deformations using the image correlation technique to identify deformed arecs. Moreover, thermographie camera was coupled with the previous device to identify heavily constraining zones. The mono directional traction was used during these experiments. In order to investigate non-textile samples made of continuous polymer (TEFLON-PTFe), we build biaxial micro traction apparatus. Lt was used under electronic (MEB) and optical microscopes. These devices have pointed out on changes in the viscous behaviour of filaments at each loading level. It was confirmed by the thermo-mechanical data, as well. Our modulation method allowed us to discriminate a fibrous structure and showed that the textile structure can be quantifiable
Motreff, Pascal. "Etude in-vivo des endoprothèses coronaires en tomographie par cohérence optique." Clermont-Ferrand 1, 2009. http://www.theses.fr/2009CLF1MM13.
Optical coherence tomography (OCT) is a high-resolution imaging technology particularly well-adapted for the study of the most superficial layers of the coronary artery wall and for stent assessment. In this book, we document our two year experience of OCT in the departement of cardiology of University Hospital, Clermont-Ferrand, France as well as the results of the OCT post-processing conducted by the ERIM team (Equipe de Recherche en Imagerie Médicale), of Auvergne University, Clermont-Ferrand, France. In the first chapter, the author details the principles behind OCT, the procedure itself and the indications for OCT examination. The feasibility and the limitations of OCT and image artefacts associated with this technology are also described using images from the author's registry of 301 OCT pull-backs. A second chapter is dedicated to the contribution OCT can make to the in-vivo analysis of coronary stents. Stent-optimization, follow-up assessment of the coronary after adverse events and clinical follow-up of drug-eluting stents are discussed with reference to recent publications and reported case-studies. The results of comparative analysis of differing neointimal coverage patterns between drug-eluting stents are also outlined and cross-referenced with others studies. In the third and final chapter, the author discusses recent material advances in OCT and in the post-processing of OCT images. He presents his own original computed analysis : in-vivo supervised analysis of stent coverage using optical coherence tomography. In conclusion, this work constitutes a reference-work for both the practical aspects of OCT and for critical analysis of OCT procedures. The author's experience of OCT is of benefit in correctly positioning this high-resolution technology in relation to the existing imaging methods. It confirms the considerable advantage OCT offers in the evaluation of vulnerable plaques and atheroma and in stent assessment. The contribution the work makes to the simplification of the procedure and to the standardization of image-analysis will also encourage the wider adoption of this promising technology as a complement to the other available imaging modalities
VAUR, DANIELE. "Endoprothese de palmaz schatz en pperipherie : a propos d'une serie de 10 cas." Toulouse 3, 1990. http://www.theses.fr/1990TOU31241.
Busseuil, David. "Etude des incidences vasculaires d'une irradiation après angioplastie et implantation d'une endoprothèse chez le lapin." Dijon, 2004. http://www.theses.fr/2004DIJOMU10.
Blain, François. "Contribution à l'étude des artefacts crées par des endoprothèses vasculaires en IRM : étude théorique in votro - in vivo." Toulouse 3, 1990. http://www.theses.fr/1990TOU31506.
Montoy, Jean-Charles. "Place actuelle de l'angioplastie et des endoprotheses vasculaires dans le traitement de l'hypertension arterielle renovasculaire." Toulouse 3, 1990. http://www.theses.fr/1990TOU31531.
RAILLAT, CHRISTOPHE. "Endoprotheses vasculaires auto-expansives et arteriopathie obliterante des membres inferieurs : resultats preliminaires de 50 premiers cas." Toulouse 3, 1988. http://www.theses.fr/1988TOU31146.
Collin, Bertrand. "Etude de la participation du stress oxydatif inflammatoire à l'installation des lésions vasculaires chez le lapin : analyse tissulaire et modulation pharmacologique." Dijon, 2006. http://www.theses.fr/2006DIJOPE01.
Our PhD works concerned 2 experimental situations responsible for vascular lesions: angioplasty with stent implantation and hypercholesterolemia. 1°) The stents were implanted in normocholesterolemic rabbits, and then we assessed the effect of atorvastatin (Ator) on the stented arteries. Ator no significantly decreased the vascular oxidative stress without effect on inflammation. The Ator did not modulate the neointimal hyperplasia but induced a down-regulation of MMP-2 associated with higher collagen content. These data underline the interest to use Ator for preventing restenosis. 2°) Hypercholesterolemic rabbits had both endothelial and myocardial contractile dysfunctions associated with an arterial oxidative stress mediated by NAD(P)H oxidases, without neither significant remodelling nor inflammation of the arteries. These data allow the early identification of major atherogenesis targets
Lamireau, Carole. "Utilisation d'endoprothèses au niveau des artères iliaques : expérience à moyen terme à propos de 12 observations." Bordeaux 2, 1994. http://www.theses.fr/1994BOR2M197.
Raymond, Nathalie. "La place des endoprothèses veineuses (stents) dans le traitement du syndrome de compression de la veine cave supérieure." Bordeaux 2, 1998. http://www.theses.fr/1998BOR23062.
Boudghene, Stambouli Franck. "Traitement endovasculaire des maladies aortiques par endoprothèses : mise au point d emodèles expérimentaux et développement d'un prototype d'endoprothèse." Paris 5, 1996. http://www.theses.fr/1996PA05CD18.
Midulla, Marco. "Application de la mécanique des fluides numérique à l'imagerie de la pathologie de l'aorte thoracique et des traitements endovasculaires modernes par pose d'endoprothèse." Toulouse 3, 2013. http://www.theses.fr/2013TOU30211.
Since 1994, when thoracic endovascular aortic repair (TEVAR) was presented to the medical community on the New England Journal of Medicine, the management of the aortic pathologies has dramatically changed in favour of a less invasive treatment associated with lower mortality and morbidity rates. A multitude of clinical trials, institutional registers and case reports has enriched the scientific literature and consecrated the new therapy which has been recently proposed as the new gold standard for such a theatre as the acute traumatic aortic rupture (ATAR). Nevertheless, little is known about the consequences of the device implantation on the native aortic status, in term either of anatomy and function. All routinely available techniques certainly provide well-detailed analysis of the aortic morphology but, so far, none of them allows for a functional exploration of the post-implantation status of the patients treated by TEVAR. The purpose of this PhD project, run over three years, was to develop functional vascular imaging techniques based on the combination of magnetic resonance (MR) and computed tomography (CT) with the CFD technology for the analysis of the thoracic aortic haemodynamics before and after the implantation of an endograft. Two main research lines have been followed: the first one was focused on the MRI-CFD combination for performing virtual simulations of the flow behaviour based on realistic patient-specific conditions. The multidisciplinary team of the OCFIA research laboratory implemented the methodology that was tested in vivo for the application in the thoracic aorta. Three-dimensional functional maps of the flow patterns were obtained and different parameters such as the velocity, vorticity and wall shear stress were qualitatively analyzed. The functional maps were compared with the morphologic images to assess their reliability. The second research line was dedicated to the application of the CFD-vascular imaging to a clinical study. The Xflow code was used with a CT combined approach for a systematic quantitative evaluation on a series of 30 patients; pre and post operative geometries were extracted and analyzed in order to detect the anatomical modifications before and after the implantation. The 3D image dataset was thereafter used for launching the CFD runs by a lagrangian approach. A quantitative comparative analysis of the wall shear stress and the vorticity was focused on the landing zones by means of two different tools. The outcomes confirmed the hypothesis of the impact of the endovascular treatment on the aortic status in terms of anatomy and functional changes. The application of the CFD methods for the functional evaluation of the thoracic aorta appeared feasible both before and after a stent-graft implantation. Over the three years two different papers have been accomplished and gained attention for publication on international journals. An implementation of the techniques is necessary to develop the clinical application of the CFD methods and weigh up their role in the whole patient management
Dorri, Megan Mahrokh. "Study for the optimization of interfacial properties between metallic substrates and polymeric coatings by plasma-based surface modification methods to improve performance of vascular stents." Doctoral thesis, Université Laval, 2017. http://hdl.handle.net/20.500.11794/28229.
Over the past 15 years, ischemic heart disease and stroke have remained the leading causes of death, worldwide. According to the World Health Organization, 15 million of the 56.4 million global deaths, in 2015, were caused only by ischemic heart disease or stroke. For the treatment of these diseases, surgical treatments have been introduced and improved to hold the blood vessels open. Among the surgical treatments, angioplasty with stenting is the most popular and the least invasive treatments. Stents, which are wire mesh tubes, prepare a mechanical support for blood vessels and hold them open to restore the blood flow. They are mostly made up of AISI316L stainless steel (SS316L), cobalt-chromium, and titanium alloys. More than half a century ago, when a stent first used, it has considerably evolved. However, release of potentially-toxic metallic ions and deterioration of mechanical properties due to corrosion, and decrease of polymeric coatings adhesion, in case of coated stents, still constitute major concerns in SS316L stents. In the case of SS316L stents, to circumvent the release of metallic ions, in the laboratory for biomaterials and bioengineering of Université Laval (LBB), a fluorocarbon (CFx) coating was previously investigated to isolate the stent completely from the biological environment. The coating also enables subsequent grafting of bioactive molecules to improve its integration in the body. The results were promising; however, the interface of SS316L/CFx needed to be modified to improve the adhesion of the CFx coating. In this Ph.D. research project, a new interface between the SS316L substrate and the CFx coating was created by plasma oxidation. The properties of this new interface, which was an oxide layer, was modified by varying the plasma-process parameters in order to preserve its properties after a 25% plastic deformation. This deformation is the maximum plastic deformation that imposes on a stent during its implantation. The new interface decreased the release of ions by decreasing the corrosion rate of the SS316L substrate by a factor of three. It was also found that the new interface produced an adequate adhesion of the CFx coating to the substrate after deformation as well as after immersion in an aqueous saline solution. The new oxide layer on SS316L was an amorphous oxide layer with an approximately 6 nm thickness, which was clearly distinguished from the polycrystalline microstructure of the substrate. The enhancement of the interface properties was ascribed to this nano-thick amorphous oxide layer, which was found to be more resistant to plastic deformation. This new oxide layer can be produced on bare-metal stents made of passivating metals. Moreover, it can create a favorable interface for coated stents, which have been used in drug-eluting stents, and also to improve stents integration in the human body.
Hertault, Adrien. "Conception et évaluation d’un stent actif pro-cicatrisant basé sur la polydopamine, un polymère biocompatible et bioinspiré." Thesis, Lille 2, 2019. http://www.theses.fr/2019LIL2S031.
Introduction: In-stent restenosis (ISR) is induced by an uncontrolled smooth muscular cells (SMC) proliferation after bare metal stent (BMS) implantation. It is associated with recurrence of symptoms and additional health costs. Drug-eluting stents have demonstrated efficiency on ISR but induce a high risk of late acute thrombosis due to a delayed struts reendothelialization. Polydopamine (PDA), a biocompatible polymer inspired from mussels byssus, has been reported to promote endothelial cells (EC) and inhibit SMC proliferation in-vitro, thus suggesting a potential pro-healing effect on the vascular wall. Furthermore, polydopamine expresses amine, catechol and quinone functions on its surface and can be used as an anchor for another therapeutic agent. This study aimed at 1) evaluating the impact of a PDA-coated stent on in-stent restenosis (ISR), 2) designing a vascular stent with a potential additional pro-healing drug, hemin, immobilized via the PDA layer.Methods: In the first part of this study, PDA coatings were obtained by dip coating of cobalt-chromium disks or stents in a dopamine solution. Disk samples were used to evaluate biocompatibility and hemocompatibility. The pro-healing potential was investigated in-vitro by seeding human EC and SMC on the different samples. In-vivo experimentations were conducted to assess the pro-healing effect in a rat model. ISR was evaluated in optic microscopy with quantification of the neointima/media (n/m) ratio after eosin/hematoxillin coloration. Quality of the struts reendothelialization was assessed with transmission electron microscopy (TEM). Molecular pathways involved in a potential pro-healing effect were investigated with western blot analyses.In the second part of this work, PDA-coated surfaces were modified with polyethylenimine (PEI) to enhance the expression of amine functions. This modified coating was characterized and cytocompatibility was assessed in-vitro. This modified surface was used to immobilized hemin, a therapeutic agent, on the sample surfaces. Functionalized surfaces were characterized, and presence of the therapeutic agent was assessed and quantified. The potential healing effect of the hemin-stent was evaluated in-vitro and in-vivo.Results: PDA surfaces demonstrated a pro-healing effect in-vitro compared to bare chromium-cobalt. PDA stents demonstrated a significant reduction in ISR compared to bare metal stents (ratio n/m = 0.48 (+/- 0.26) versus 0.83 (+/- 0.42), p<0.001) in the rat model. TEM analyses confirmed the presence of neointima surrounding the struts in each group and revealed a thinner neointima layer in the PDA-stent group compared to BMS, with similar ultrastructures of the cells facing the arterial lumen. Western blot analyses identified a trend to an increased activation of p38 MAPK phosphorylation and its anti-proliferative effects on vascular SMC which could explain the results observed in the histomorphometric analyses.Immobilization of PEI was achieved through Michael addition and Shift base reaction on PDA coatings, and successfully enriched the surfaces with amino groups without decreasing cytocompatibility. Hemin was successfully grafted on the PDA-PEI surfaces via amide bounds (approximately 10ng of hemin per cm²). Hemin-coated surfaces demonstrated no superiority in-vitro or in-vivo to PDA alone.Conclusion: The expected pro-healing effect of PDA-coating on the arterial wall seems to be confirmed in this in-vivo model. This biocompatible polymer could intrinsically limit in-stent restenosis. Additionally, it also offers the possibility to immobilize many relevant drugs on its surface through amine functions providing potential synergistic effects
Mougin, Justine. "Mise au point et optimisation d'un modèle lagomorphe hypercholestérolémique de resténose intra-stent et application pour le développement d'un stent obtenu par électrofilage." Electronic Thesis or Diss., Université de Lille (2022-....), 2023. http://www.theses.fr/2023ULILS019.
Objective: This study aimed to evaluate the use of a double injured atherosclerotic iliac rabbit model for myointimal hyperplasia evaluation. Secondarily, this animal model was use for pre clincial evaluation of a new anti-in stent restenosis simvastatin electrospun covered stent. Methods: Twenty four New Zealand White (NZW) rabbits were included in this study. In order to enhance and accelerate atherogenesis, atherogenic diet (0.3% cholesterol and 4.9% coconut oil) and mechanical endothelial injury of iliac artery were used. Twelve rabbits (24 iliac arteries) were used to evaluate the benefit of intimal balloon injury compared to the diet alone on myointimal hyperplasia. On day 7, rabbits beneficiated balloon iliac injury on the left side only. Eight weeks they were scarified and iliac arteries were harvested to histologic examination and comparaison. Twelve rabbits were included in the second evaluation to compare anti instent restenosis effect of a new drug eluting chrome-cobalt stent (DES) coated with polycyclodextrin-chitosan-simvastatin polymer after electrospinning technique. Balloon injury were performed on both iliacs on day 7, then stenting of BMS on right iliac and DES on left iliac and animals were sacrified 4 weeks later after angiography for histologic examination. Results: Balloon iliac injuries (BI) revealed a significant higher Schwartz injury score (0.599±0.368 control vs 1.150±0.306 BI, p=0.013), percentage of stenosis (25.7±19.1 control vs 49.9±21.9 BI, p=0.012) and ratio collagen (0.252 ± 0.017 control vs 0.365 ± 0.011 BI, p=0.0001) than atherosclerotic diet only. Five rabbits died before the end of the protocol. After appaired comparison of BMS and DES, results were significantly better for BMS and pre-euthanasia angiography revealed that 3/7 DES were thrombosed versus 0/7 for BMS. Conclusions : Association of atherogenic diet and balloon injuries allow to obtain important neointimal hyperplasia and wall remodeling in rabbit iliac arteries that confirm its interest as in stent restenosis model for new DES
Sobocinski, Jonathan. "Fonctionnalisation de stents vasculaires par des matrices polymères contenant des molécules bioactives." Phd thesis, Université du Droit et de la Santé - Lille II, 2013. http://tel.archives-ouvertes.fr/tel-01019703.
Boufi, Mourad. "Caractérisations morphométriques et biomécaniques de l'aorte thoracique." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM5000.
Objectives: characterize (1) arch morphometry to examine criteria favoring complications after thoracic endovascular aortic repair (TEVAR) and feasibility of « off-the-shelf » fenestrated devices.(2) mechanical properties of ascending aorta (AA) in swine and humans, with and without aortic dissection.Materials and methods : Morphometric characterization : Computed tomographic angiography were analysed to calculate elementary morphometric, geometric and supra-aortic trunks data Mechanical characterization : In vivo: arterial pressure and diameters measured with echocardiophy are used to calculate elastic parameters.Ex vivo: biaxial tensile testing performed on AA plus histological and microstructural analysis. Results :Morphometric characterization : In > 75% of cases supra-aortic branches are positioned within 15° of each other and distances between them have a variability of ± 4 mm.Independant factors associated with endoleak, bird beak and mis-positioning are respectively : (1) short proximal neck (2) landing zone angulation (cut-off value: 51°); and (3) tortuosity index (cut-off value: 1.68). Mechanical characterization : in vivo: greater compliance of swine aorta compared to humans and a stiffer aorta in case of aortic dissectionBiaxial testing: linear stress-strain behavior of swine aorta, compared to a non linear one in human. Conclusion : our study reveals :- the impact of anatomy on complications occurrence after TEVAR, and suitable arguments for « off-the-shelf » fenestrated devices.- swine model is inappropriate to test AA dedicated stent-graft.- stiffer wall in aortic dissection has consequences on the choice of futur devices dedicated to AA
Kaladji, Adrien. "Apport de l'assistance par ordinateur lors de la pose d'endoprothèse aortique." Thesis, Rennes 1, 2015. http://www.theses.fr/2015REN1B008/document.
The development of endovascular aortic procedures is growing. These mini-invasive techniques allow a reduction of surgical trauma, usually important in conventional open surgery. The technical limitations of endovascular repair are pushed to special aortic localizations which were in the past decade indication for open repair. Success and efficiency of such procedures are based on the development and the implementation of decision-making tools. This work aims to improve endovascular procedures thanks to a better utilization of pre and intraoperative imaging. This approach is in the line with the framework of computer-assisted surgery whose concepts are applied to vascular surgery. The optimization of endograft deployment is considered in three steps. The first part is dedicated to preoperative imaging analysis and shows the limits of the current sizing tools. The accuracy of a new measurement criterion is assessed (outer curvature length). The second part deals with intraoperative imaging and shows the contribution of augmented reality in endovascular aortic repair. In the last part, image guided surgery on soft tissues is addressed, especially the arterial deformations occurring during endovascular procedures which disprove rigid registration in fusion imaging. The use of finite element simulation to deal with this issue is presented. We report an original approach based on a predictive model of deformations using finite element simulation with geometrical and anatomo-mechanical patient specific parameters extracted from the preoperative CT-scan
Major, Annie. "Analyse des mécanismes d'échec des endoprothèses couvertes et stimulation de la formation néointimale in vitro : vers un meilleur traitement des anévrismes de l'aorte abdominale." Thèse, 2006. http://hdl.handle.net/1866/15725.