Дисертації: "EDN"

1

Richard, Ronald. "Atelier du monde en travail implique EDN, BLL, NOE CHAOSMOSE." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ40555.pdf.

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2

Sierra, Benito Cristina. "Alteraciones funcionales y estructurales precoces edn la circulación cerebral en la hipertensión arterial esencial." Doctoral thesis, Universitat de Barcelona, 2002. http://hdl.handle.net/10803/2160.

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HIPOTESIS DE TRABAJO Y OBJETIVOS: La hipertensión arterial (HTA), además de la edad, es el factor de riesgo que más se asocia a la presencia de lesiones cerebrales de sustancia blanca (LSB). De hecho, para la mayoría de autores, estas lesiones son consideradas como un marcador precoz de lesión cerebral en la HTA y relacionadas con el proceso arterioscleroso. No obstante, su etiopatogenia es compleja y supone la implicación de factores genéticos. La relación entre las LSB y los diferentes parámetros clínicos y biológicos asociados a la HTA no está suficientemente definida. Por otra parte, la mayoría de estudios realizados hasta la fecha se han efectuado en población anciana, o en un amplio rango de edades, o se han incluido pacientes hipertensos con tratamiento antihipertensivo, factores todos ellos que han podido actuar como factores de confusión. El objetivo del presente trabajo es determinar los posibles factores clínicos y biológicos relacionados con la presencia de LSB en pacientes asintomáticos de mediana edad afectos de hipertensión arterial esencial nunca tratada.

METODOLOGIA: Se han incluido 66 pacientes hipertensos esenciales de ambos sexos, de edades comprendidas entre 50-60 años, nunca tratados, y sin evidencia de enfermedad cardiovascular. Los pacientes con diabetes mellitus y/o ingesta enólica >30 grs/día, y aquéllos con una estenosis carotídea >50% fueron excluidos del estudio. Se realizaron las siguientes exploraciones: MAPA de 24 horas, ecocardiograma, y determinación del genotipo del gen de la enzima de conversión de la angiotensina (ECA) mediante PCR. A todos los pacientes se les realizó una resonancia magnética cerebral (RM) y se les clasificó en dos grupos, en función de la presencia o ausencia de LSB.

RESULTADOS: Veintisiete (40.9%) pacientes hipertensos mostraban LSB en la RM. Los pacientes con LSB tenían unas cifras de presión arterial (PA) sistólica, diastólica, y presión de pulso, significativamente mayores que los pacientes hipertensos sin LSB, tanto en la clínica como en la MAPA. La presencia de hipertrofia del ventrículo izquierdo (HVI) en pacientes hipertensos con LSB era significativamente mayor que en hipertensos sin LSB (88.4% versus 58.3%; P=0.01). De la misma manera, la presencia de una HVI concéntrica era significativamente mayor (P=0.002) en pacientes con LSB (54%) que en hipertensos sin LSB (11%). El riesgo relativo de HVI concéntrica para la presencia de LSB, independiente de los valores de PA, fue de 8.22 (95% IC: 2.06-32.78). En referencia al estudio genético, se objetivó que los pacientes con LSB presentaban con mayor frecuencia, en comparación con los pacientes sin LSB, tanto el alelo D (74% versus 51.4%; P=0.014) como el genotipo DD (64% versus 28.6%; P=0.022) del gen de la ECA.

CONCLUSIONES: La presencia de LSB en pacientes hipertensos asintomáticos de mediana edad es un hallazgo frecuente y está relacionado con la severidad de la elevación de la PA. La existencia de estas lesiones está asociada a la presencia de una HVI concéntrica. De la misma manera, y de forma independiente de las cifras de PA, la presencia del genotipo DD del gen de la ECA podría ser un factor predisponente para el desarrollo de LSB en pacientes con hipertensión arterial esencial.

PRODUCCIÓN CIENTÍFICA:

- Sierra C, de la Sierra A, Mercader J, Gómez-Angelats E, Urbano-Márquez A, Coca A. "Silent cerebral white matter lesions in middle-aged essential hypertensive patients". J Hypertens 2002;20:519-524. FACTOR DE IMPACTO: 4.210

- Sierra C, de la Sierra A, Paré JC, Gómez-Angelats E, Coca A. "Correlation between silent cerebral white matter lesions and left ventricular mass and geometry in essential hypertension". Am J Hypertens 2002;15:507-512. FACTOR DE IMPACTO: 2.755

- Sierra C, Coca A, Gómez-Angelats E, Poch E, Sobrino J, de la Sierra A. "Renin-angiotensin system genetic polymorphisms and cerebral white lesions in essential hypertension". Hypertension 2002;39[part 2]:343-347. FACTOR DE IMPACTO: 5.364

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3

Lemoine, Anaïs. "Étude longitudinale et multiomique à la recherche de biomarqueurs fécaux ou salivaires associés au Syndrome d'Entérocolite Induite par les Protéines Alimentaires (SEIPA) chez l'enfant." Electronic Thesis or Diss., Sorbonne université, 2024. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2024SORUS128.pdf.

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Contexte : Le SEIPA est une allergie alimentaire non IgE-médiée particulière, répondant à des critères diagnostiques précis. Le traitement est l'éviction des aliments en cause. Il n'existe pas de biomarqueur sérique confirmant le diagnostic, ou prédisant l'acquisition de la tolérance. Seul le test de provocation par voie orale (TPO) permet d'évaluer régulièrement la tolérance à l'allergène en cause. L'évolution est le plus souvent favorable chez l'enfant vers l'âge scolaire. Cependant, la sévérité des symptômes et l'absence d'IgE spécifiques justifient une recherche sur le SEIPA pour mieux comprendre la physiopathologie. Hypothèses : Le SEIPA serait associé à une dysbiose digestive, une dysimmunité locale au niveau digestif, une inflammation intestinale chronique, et une augmentation de la perméabilité intestinale. L'inflammation et la perméabilité seraient majorées lors d'une réaction allergique aiguë. Après acquisition de la tolérance, tous ces paramètres reviendraient à la normale. Objectifs : Décrire de manière longitudinale les microbiotes fécaux et salivaires des patients pédiatriques avec un SEIPA, pendant l'allergie et après la tolérance, ainsi que des biomarqueurs d'intérêt évaluant l'inflammation, la perméabilité et la dysimmunité digestive, comparativement à une cohorte de référence. Matériels et méthodes : Des prélèvements fécaux et salivaires ont été collectés chez les enfants avec un SEIPA suivi dans plusieurs hôpitaux de l'AP-HP, après le diagnostic sous régime d'éviction, et après acquisition de la tolérance, ainsi que chez des témoins appariés aux mêmes âges (ratio 1:1). Des prélèvements de selles supplémentaires ont également été récoltés avant et après les TPO. La composition du microbiote a été analysée par séquençage du gène de l'ARN r16s (V3-V4). La fonction du microbiote fécal a été estimée par dosage des acides gras à chaine courte (AGCC) (chromatographie en phase gazeuse). La calprotectine fécale, la neurotoxine dérivée des éosinophiles (EDN), les IgA sécrétoires fécales, et la zonuline fécale ont évalué l'inflammation, l'immunité et la perméabilité intestinale (ELISA).Résultats principaux : De décembre 2019 à mai 2023, 38 patients ont été inclus (âge moyen : 1,3 ans). A l'inclusion, les patients allergiques avaient une dysbiose fécale et salivaire, s'exprimant par une diminution de l'alpha-diversité, une béta-diversité différente, plusieurs genres bactériens différents, et une augmentation de l'abondance relative de l'acétate par rapport aux témoins appariés. Les patients allergiques n'avaient pas d'inflammation intestinale sous régime d'éviction (calprotectine, EDN), mais seulement de manière aiguë et transitoire après une réaction allergique. Les taux d'IgA sécrétoires fécales étaient plus élevés chez les patients allergiques que chez les témoins ou chez les patients tolérants. La zonuline était similaire entre les patients et les témoins. Après acquisition de la tolérance, chez les 22 patients devenus tolérants, les microbiotes fécal et salivaire se sont rapprochés partiellement de ceux des témoins. Les AGCC et les IgA sécrétoires se sont normalisés (augmentation de l'abondance relative du butyrate, baisse du taux d'IgA). Conclusions : D'après les résultats de cette cohorte, et selon les données antérieures de la littérature scientifique, les enfants avec un SEIPA ont une dysbiose intestinale avant le début de l'allergie, une dysbiose intestinale et salivaire pendant l'allergie jusqu'à l'acquisition de la tolérance, puis un retour du microbiote proche de celui d'enfants sains. La réponse immunitaire adaptative locale est exagérée au cours de la pathologie, avec une augmentation des IgA sécrétoires fécales chez les individus allergiques par rapport aux témoins, et une normalisation après la tolérance. Le rôle exact de ces IgA n'est pas clairement identifié
Background: FPIES is a non-IgE-mediated food allergy, meeting precise diagnostic criteria. Treatment involves avoiding the offending food. There is no serum biomarker confirming the diagnosis or predicting the development of tolerance. Only the oral food challenge (OFC) regularly assesses allergenic tolerance. In most cases, children acquire spontaneous tolerance at school age. However, the severity of symptoms and the absence of specific IgE justify research into FPIES to gain a better understanding of the pathophysiology.Hypothesis: FPIES is associated with digestive dysbiosis, local digestive dysimmunity, chronic intestinal inflammation and increased intestinal permeability. Inflammation and permeability are exacerbated during an acute allergic reaction. Once tolerance is acquired, all these parameters return to normal. Objectives: To provide a longitudinal description of the faecal and salivary microbiota of paediatric patients with SEIPA, at the times of allergy and tolerance, as well as biomarkers of interest assessing inflammation, permeability and digestive dysimmunity, compared with a reference cohort. Materials and methods: Faecal and salivary samples were collected from children with FPIES followed in several AP-HP hospitals, after diagnosis on an elimination diet, and after acquiring tolerance, as well as from matched controls at the same ages (1:1 ratio). Additional stool samples were also collected before and after OFC. The composition of the microbiota was analysed by r16s RNA gene sequencing (V3-V4). The function of the faecal microbiota was estimated by measuring short-chain fatty acids (SCFA) (gas chromatography). Faecal calprotectin, eosinophil-derived neurotoxin (EDN), faecal secretory IgA, and faecal zonulin assessed inflammation, immunity and intestinal permeability (ELISA).Main results: From December 2019 to May 2023, 38 patients were included (mean age: 1.3 years). At inclusion, allergic patients had faecal and salivary dysbiosis, expressed as decreased alpha-diversity, different beta-diversity, several different bacterial genera, and increased relative abundance of acetate compared with matched controls. Allergic patients did not have intestinal inflammation on elimination diet (calprotectin, EDN), but only acutely and transiently after an allergic reaction. Levels of faecal secretory IgA were higher in allergic patients than in controls or tolerant patients. Zonulin was similar between patients and controls. After acquiring tolerance, in the 22 patients becoming tolerant, faecal and salivary microbiota partially approximated those of controls. Secretory AGCC and IgA levels normalised (increase in relative butyrate, decrease in IgA). Conclusions: According to the results of this cohort, and to previous data in the scientific literature, children with FPIES have a gut dysbiosis before the onset of allergy, gut and salivary dysbiosis during allergy until the acquisition of tolerance, and then a return of a microbiota close to that of healthy children. The local adaptive immune response is exaggerated during the disease, with an increase in faecal secretory IgA in allergic individuals compared with controls, and normalisation after tolerance. The exact role of this IgA is not clearly identified

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Олешко, Тетяна Богданівна, Татьяна Богдановна Олешко, Tetiana Bohdanivna Oleshko, Діана Юріївна Свириденко, Диана Юрьевна Свириденко, Diana Yuriivna Svyrydenko, Вікторія Юріївна Гарбузова, Виктория Юрьевна Гарбузова та Viktoriia Yuriivna Harbuzova. "Асоціація Lys198Asn поліморфних варіантів гена ендотеліну-1 (EDN−1) з деякими факторами ризику ішемічного атеротромботичного інсульту". Thesis, Інститут фізіології ім. О.О. Богомольця НАНУ, 2016. http://essuir.sumdu.edu.ua/handle/123456789/51710.

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Ішемічний інсульт поряд з ішемічною хворобою серця та онкопатологією продовжує утримувати лідируючі позиції серед причин захворюваності, смертності та інвалідизації населення як в Україні так і в цілому світі. Важливий вплив на розвиток інсульту здійснюють фактори ризику, а саме артеріальна гіпертензія (АГ), стать, підвищений індекс маси тіла (ІМТ) та куріння. У патогенезі ішемічного атеротромботичного інсульту (ІАТІ) провідну роль відіграє ендотеліальна дисфункція (ЕД), в розвиток якої важливий внесок здійснює генетична схильність.

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Suazo, Sanhueza José Lorenzo. "Estudio de asociación entre un microsatélite del gen EDN 1, ubicado en el cromosoma 6, y la fisura labiopalatina no sindrómica en una población chilena." Tesis, Universidad de Chile, 1999. http://repositorio.uchile.cl/handle/2250/110563.

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6

Pejznochová, Jana. "Logistické technologie se zaměřením na ECR v řetězcích obchodního typu." Master's thesis, Vysoká škola ekonomická v Praze, 2006. http://www.nusl.cz/ntk/nusl-460.

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Práce rozebírá logistické technologie, podrobněji Efficient Consumer Response. Zabývá se příčinami vzniku, stručnou historií, prvky, přínosy pro podniky a implementací ECR v podniku. Cílem práce je ukázat, jak ECR funguje a jak je uplatňováno v praxi u výrobních i obchodních společností, jak ECR vnímají koneční zákazníci, a jak by při zavádění technologie měly postupovat podniky, které s ECR nemají zkušenosti.

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Ye, Feng Shen Yilian. "Entwicklung einer einheitlichen Datenstruktur und bedienungsfreundlichen Benutzerführung für ein EDV-Tool." [S.l. : s.n.], 2004. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB11482125.

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8

Canli, Sedat. "Thickness Analysis Of Thin Films By Energy Dispersive X-ray Spectroscopy." Master's thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/12612822/index.pdf.

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EDS is a tool for quantitative and qualitative analysis of the materials. In electron microscopy, the energy of the electrons determines the depth of the region where the X-rays come from. By varying the energy of the electrons, the depth of the region where the X-rays come from can be changed. If a thin film is used as a specimen, different quantitative ratios of the elements for different electron energies can be obtained. Unique thickness of a specific film on a specific substrate gives unique energy-ratio diagram so the thickness of a thin film can be calculated by analyzing the fingerprints of the energy-ratio diagram of the EDS data obtained from the film.

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Efthymiou, Georgios. "Etude d’assemblage et des fonctions des isoformes oncofoetales de la fibronectine." Electronic Thesis or Diss., Université Côte d'Azur (ComUE), 2019. http://www.theses.fr/2019AZUR6024.

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La matrice extracellulaire (MEC) constitue une plateforme fibrillaire intégrant l'action des signaux chimiques et mécaniques de l'environnement. La fibronectine (FN), un composant majeur de la MEC, est au centre de cette plateforme de biorégulation et module de nombreuses actions biologiques telles que l’adhésion et la motilité cellulaires, la prolifération et la différenciation, ainsi que la structure et le dépôt de la MEC. La FN se présente sous deux formes : la FN plasmatique (pFN) et la FN cellulaire (cFN), dite « oncofoetale ». Cette dernière est nommée ainsi pour son expression uniquement au cours du développement et dans certaines conditions physiopathologiques (réparation tissulaire, inflammation et cancer). La différence entre les deux est l’existence dans la cFN des domaines supplémentaires EDB et EDA, qui résultent d’un épissage alternatif. Comment la présence de ces « extra-domaines », EDA et EDB , régit l'assemblage des FN et comment les variantes assemblées régulent le comportement des cellules est en grande partie inconnu. Des études de délétion ciblées d’un seul domaine chez la souris ont révélé le rôle de l'EDA dans des phénomènes très variés dont la morphogenèse des valves lymphatiques, l'athérosclérose et la cicatrisation / fibrose. Au niveau moléculaire, l'inclusion de l'EDA élargit le répertoire des récepteurs cellulaires de la FN (intégrines α4β1, α7β1 et TLR4). A ce jour, aucun récepteur n'a été rapporté pour l’EDB. De ce fait il a été proposé que sa présence modifierait la conformation du site de liaison de FN aux cellules et faciliterait ainsi l’assemblage fibrillaire induit par les intégrines via des mécanismes qui restent à établir.Le but des travaux de cette thèse était de décoder les rôles de l'EDA et de l'EDB de la FN, et plus précisément de :1) étudier l'impact de la présence des domaines EDA et EDB sur l'assemblage fibrillaire de la FN à la surface de cellules compétentes pour l'assemblage, et2) déterminer comment la présence de l’EDB et de l’EDA influence les propriétés biochimiques, physiques et fonctionnelles de la matrice, qui à leur tour affectent le comportement des cellules qui y sont attachées.Dans un premier temps l’équipe a développé un ensemble d'outils biologiques composé de : i) vecteurs lentiviraux hébergeant la séquence codante complète du gène de la cFN humaine contenant l’un, les deux ou aucun des « extra-domaines » alternativement épissés, ii) des variants de FN recombinants purifiés, iii) des fibroblastes embryonnaires de souris FN -/- (Fn1 -/- MEF), et iv) des MEF exprimant des variantes de FN. Cette batterie outils uniques a été utilisée pour étudier l'assemblage spécifique de variantes par les fibroblastes et les effets de réseaux de cFN homogène sur le comportement cellulaire.Nos résultats ont montré que les « extra-domaines « de la FN sont responsables au niveau des fibroblastes du réglage fin de l’amplitude de plusieurs réponses dont l’assemblage de la matrice, la croissance et le métabolisme énergétique. En utilisant une approche informatique « non-biaisée », nous avons démontré que la présence des « extra-domaines » modifie la structure de la matrice de la FN déposée par les fibroblastes. Ceci témoigne d’événements de signalisation cellulaire différents, qui sont susceptibles de modifier aussi bien les réponses précoces que tardives induites par la FN. Les matrices variant-spécifiques que nous avons développées représentent des outils très puissants pour décrypter les fonctions des « extra-domaines » de la FN dans les multiples types de cellules impliquées non seulement dans des réponses physiologiques mais également dans des situations pathologiques
The Extracellular Matrix (ECM) constitutes a fibrillar platform that integrates the action of chemical and mechanical cues from the environment. Fibronectin (FN), a major component of the ECM, is at the center of this bioregulatory stage, modulating numerous biological procedures such as cell adhesion and motility, cell proliferation and differentiation, as well as ECM deposition and structure. FN is found in two forms: plasma FN (pFN) and cellular FN (cFN). cFN differs from pFN by the presence of alternatively spliced Extra Domains, namely EDB and EDA. Each of these alternatively spliced regions is encoded by a single exon, the regulation of which is strictly regulated and limited to embryonic tissues, as well as pathophysiological conditions such as wound healing, inflammation, and cancer. The term “oncofetal” was coined in order to describe FN isoforms harboring either of the Extra Domains, that are normally absent in adult tissues.How the presence of EDA and EDB regulates FN assembly and how the assembled variants regulate cell behavior is largely unknown. Single Extra Domain-targeted deletion studies in the mouse have revealed roles for EDA in the morphogenesis of lymphatic valves, atherosclerosis, and wound healing/fibrosis. Mechanistically, the inclusion of EDA expands the repertoire of cellular FN receptors (α4β1, α7β1 integrins and TLR4). To date, no ligand has been reported for EDB. Rather, its presence has been postulated to alter the conformation of the cell-binding domain of FN and to facilitate integrin-driven fibrillar assembly by mechanisms that remain to be established.The aim of this dissertation is to provide more insight regarding the roles of the FN Extra Domains EDA and EDB, and more specifically:1) To investigate how the presence of alternatively spliced EDA and EDB domains affect the fibrillar assembly of FN at the surface of assembly-competent cells, and2) To determining how the presence of EDB and EDA influences the biochemical, physical, and functional properties of the matrix that in turn affect the behavior of cells attached to it.Here we present a biological toolset composed of : i) lentiviral vectors harboring the full-length coding sequence of human cFN containing one, both, or none of the alternatively-spliced Extra Domains, ii) purified recombinant FN variants, iii) FN-null mouse embryo fibroblasts (MEFs) and iv) FN variant-expressing MEFs. These unique tools were used to study variant-specific assembly by fibroblasts and the effects of homogeneous cFN networks on cell behavior.Utilizing an unbiased computational approach, we document that the presence of the Extra Domains results in a distinct pattern of FN deposition and assembly that in turn influences both early and late signaling events that control cell proliferation as well as cell contractility. Finally, we present a series of novel data that point towards a FN-impacted control of cell energetics.We conclude that FN Extra Domains are responsible for the fine-tuning of the extent of several cellular processes that can reflect strict regulation in pathophysiological procedures such as tissue repair, fibrosis, and tumor progression

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Bayen, Térence. "Etude de quelques problèmes de contrôle optimal issus des EDP et des EDO." Habilitation à diriger des recherches, Université Montpellier II - Sciences et Techniques du Languedoc, 2013. http://tel.archives-ouvertes.fr/tel-00919030.

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Le premier chapitre de ce mémoire porte sur l'étude des minimum forts pour des problèmes de contrôle optimal gouvernés par des EDP semi-linéaires elliptiques et paraboliques avec contraintes intégrales sur l'état final. Le second chapitre porte sur l'étude du problème de temps minimal pour un système de type chemostat en présence de points singuliers stationnaires. On y étudie également un problème de contrôle optimal pour un système chemostat avec deux espèces en compétition et qui comporte une courbe de non-contrôlabilité. Le troisième chapitre s'intéresse à la synthèse d'un contrôle optimal par retour d'état pour un problème de temps minimal issu d'un système fed-batch, notamment en présence d'un contrôle impulsionnel. Le quatrième chapitre étudie deux problèmes de contrôle optimal sous contraintes d'état périodiques. Enfin, le dernier chapitre traite de problèmes d'optimisation de forme géométriques sous contraintes de convexité. Cette dernière est formulée comme une contrainte semi-définie, ce qui permet ensuite d'utiliser la programmation SDP pour minimiser la fonction coût.

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Schäuble, Holger. "Erosionsprognosen mit GIS und EDV ein Vergleich verschiedener Bewertungskonzepte am Beispiel einer Gäulandschaft /." [S.l. : s.n.], 2005. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB12046203.

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12

Chakraborty, Pinaki. "Tool Life and Flank Wear Modeling of Physical Vapour Deposited TiAlN/TiN Multilayer Coated Carbide End Mill Inserts when Machining 4340 Steel Under Dry and Semi-Dry Cutting Conditions." Scholarly Repository, 2008. http://scholarlyrepository.miami.edu/oa_dissertations/22.

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This study investigates the tool wear of advanced PVD TiALN/TiN multilayer coated end mill inserts when dry and semi-dry machining 4340 low alloy medium carbon steel. A factorial design of experiment setup consisting of two levels of speed, three levels of feed, two levels of depth of cut, and two levels of cutting conditions (semi-dry and dry) was used for the study. The combination of cutting conditions that gave the best response for different components of cutting force, cutting power, surface roughness and tool life were determined using MANOVA & ANOVA analysis and Tukey comparison of means test using MINITAB statistical software package. From a study of the Energy Dispersive X ray (EDX) analysis and primary back scatter images obtained from the worn out crater surface of the insert, it was observed that diffusion wear prevailed under both dry and semi-dry machining conditions. A tool life model was developed using multiple regression analysis within the range of cutting conditions selected. A model for flank wear progression was also developed using mixed effects modeling technique using S Plus statistical software package. This technique takes into account between and within work piece variations during end milling and produces a very accurate model for tool wear progression. This is the first time application of the mixed effects modeling technique in metal cutting literature.

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Partsch, Sabine. "Konzeption und Aufbau eines Benutzerforums für ein EDM/PDM-System im Intranet der DaimlerChrysler AG." [S.l. : s.n.], 2003. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB11675528.

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Zocher, Peter. "Edo Osterloh - vom Theologen zum christlichen Politiker : eine Fallstudie zum Verhältnis von Theologie und Politik im 20. Jahrhundert." Göttingen Vandenhoeck & Ruprecht, 2007. http://bvbr.bib-bvb.de:8991/F?func=service&docl̲ibrary=BVB01&docn̲umber=015783053&linen̲umber=0003&funcc̲ode=DBR̲ECORDS&servicet̲ype=MEDIA.

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Dutra-Corrêa, Maristela [UNESP]. "Ablação de esmalte e dentina bovinos e humanos com laser de Ti:safira no regime de femtossegundos: análises morfológicas e fisico-químicas comparativas." Universidade Estadual Paulista (UNESP), 2008. http://hdl.handle.net/11449/101347.

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Dentes bovinos têm sido convencionalmente utilizados em pesquisas odontológicas substituindo dentes humanos. Diferenças nas propriedades físico-químicas, estruturais e morfológicas dos substratos representarão diferenças na resposta frente a diversos tratamentos. Foi investigada a ablação em esmalte e dentina de dentes bovinos (30) e humanos (30) com laser de Ti:Safira, no regime de femtossegundos (70fs), com λ= 800±1 nm, taxa de repetição=1 KHz, utilizando diferentes potências médias com diferentes tempos de exposição. Foram realizadas análises morfológicas e físico-químicas. Os corpos-de-prova foram observados ao microscópio de luz, ao MEV e analisados por EDX. As microcavidades em esmalte (bovino e humano) apresentaram ablação precisa, integridade e definição das margens. No esmalte humano não houve danos térmicos ou microfraturas; o bovino apresentou microfraturas, provavelmente resultado de sua menor resistência à ablação com laser. As microcavidades da dentina (bovina e humana) apresentaram bordas definidas, entretanto com microfraturas, sendo que na dentina bovina foram mais numerosas, mais amplas e mais intensas, mostrando maior susceptibilidade frente à irradiação com laser. Quanto à proporção Ca/P, as alterações proporcionais entre números de átomos de Ca em relação ao P, não foram estatisticamente significantes, para nenhum tecido. Conclui-se que o laser de Ti:Safira no regime de femtossegundos, além de muito rápido, potente e seguro, tem a vantagem de poder ser bem controlado e preciso, promovendo profundidades pequenas e específicas. Diante dos resultados e dependendo do tipo de tecido, fica evidente a necessidade de prévio conhecimento das diferenças entre eles antes da direta extrapolação dos resultados obtidos em substrato bovino para humano.
Bovine teeth have been conventionally used in dental research to replace human teeth. Differences in the physicochemical, structural and morphological properties of these substrates cause differences in their response to several treatments. This study investigated the ablation of enamel and dentin of bovine teeth (30) and human teeth (30) using a Ti:Sapphire laser at Femtosecond pulse width (70fs), λ= 800±1nm and repetition rate of 1 KHz. Different output power levels and irradiation times were investigated. Morphological and physicochemical analysis were conducted. Irradiated specimens were evaluated under light microscopy, SEM and EDX. Microcavities in bovine and human enamel showed accurate ablation, with sharp margins and preserved morphologies. Human enamel did not exhibit induced thermal damage or microfractures; bovine enamel presented microfractures, probably due a lower resistance to laser ablation. The microcavities in dentin (bovine and human) presented defined borders, yet with microfractures, which were more frequent, wider and more intense in the bovine dentin, demonstrating a higher susceptibility to laser irradiation. Concerning the Ca/P ratio, the proportional alterations between the numbers of Ca atoms compared to P atoms were not statistically significant for any tissue. In this study Femtosecond Ti:Sapphire laser showed to be a fast, powerful and safe ablation system. Additionally, it promotes removal at small and specific depths. Considering the present results and depending on the type of tissue, it is clear that previous knowledge on the differences between them is required before direct extrapolation of results obtained in bovine substrate to the human substrate.

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Bourdelle, Franck. "Thermobaromètrie des phylloscilicates dans les séries naturelles : conditions de la diagénèse et du métamorphisme de bas degré." Phd thesis, Université Paris Sud - Paris XI, 2011. http://tel.archives-ouvertes.fr/tel-00616543.

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Les illites et les chlorites sont des minéraux ubiquistes dans la plupart des roches diagénétiques. Leurs compositions chimiques dépendent des conditions physiques subies (pression, P ; température, T) et de la composition de l'encaissant (e.g. Vidal et al., 1999 ; Parra et al., 2002a, 2002b). Ces minéraux peuvent donc potentiellement être de très bons marqueurs de l'histoire de l'enfouissement, et sont à la base de nombreuses méthodes empiriques ou thermodynamiques d'estimation des conditions P-T.Une compilation de données naturelles et la comparaison des thermobaromètres existants ont permis d'établir leurs limitations respectives. Pour s'en affranchir, un nouveau modèle ordonné de solution solide pour les chlorites a été développé, qui rend compte des forts contenus en silicium observés dans les chlorites naturelles de basses températures. La calibration de ce nouveau thermobaromètre sur des domaines géologiques variés de BT-BP a été testée sur des analyses de chlorites naturelles de la Gulf Coast (Texas) au pic de température (où les données P-T ont été mesurées in situ) et montre d'excellents résultats. Concernant les illites, le modèle thermodynamique le plus abouti (Dubacq et al., 2010) a également été testé de manière à estimer sa précision. L'étude a été complétée par la quantification de l'influence du fer ferrique. Les analyses chimiques utilisées ont été obtenues grâce à un protocole analytique à haute résolution spatiale. Alliant FIB et MET-EDS, ce protocole a permis une étude microtexturale et chimique fine des chlorites et des illites. Il en ressort que ces minéraux possèdent une diversité intracristalline dans leurs compositions et que la zonation chimique résultante apparaît comme une potentielle source d'erreurs dans la calibration des thermobaromètres, tout en permettant d'envisager la notion d'équilibre à l'échelle locale.Cette approche a été utilisée pour quantifier les trajets P-T d'unités géologiques des Alpes de Glarus. Ces résultats, comparés à ceux obtenus avec des méthodes thermobarométriques conventionnelles, donnent une bonne image des processus d'enfouissement et d'exhumation des roches de basse température. Ainsi, il apparaît que chaque composition enregistre une portion du chemin P-T rétrograde. D'une manière générale, chaque zone d'un même cristal renvoie à une partie de l'histoire de la roche.

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Wieland, Volker. "Zur Qualität der Dokumentation der Schockraumversorgung schwer Traumatisierter: ein Vergleich von primär EDV-gestützter und handschriftlicher Dokumentation." [S.l. : s.n.], 2006. http://nbn-resolving.de/urn:nbn:de:bsz:289-vts-56983.

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Böckler, Stefanie [Verfasser]. "End-of-Life Entscheidungen von Patienten mit Amyotropher Lateralsklerose: Ein interkultureller Vergleich zwischen Schweden und Deutschland / Stefanie Böckler." Ulm : Universität Ulm, 2018. http://d-nb.info/1151938254/34.

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Císař, Daniel. "Přístupy k transformaci popisu procesů do BPEL." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-19146.

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In this work, I dealt with the field of Business Process Managent and Service Oriented Architecture. First I tried a comprehensive conceptual view of both through the definition of important principles. In BPM as a disciline I identified "life-cycle" as the most important principle for process optimization tools. For service-oriented architecture, I had to reduce the view to important principles related to composition of services. An important starting point in my work are the definitions of processes and services and their roles in BPM systems. It is a simplified view that helps connect modeled processes to Web services. Web services and orchestration is the most popular and most common usage of the service-oriented architecture. Composition is another important building block of SOA and is the basis for more realistic goals of SOA, such as greater enterprise agility, more efficient utilization of resources in the enterprise, etc. BPM discipline combines multiple elements and as it is typicaly multidisciplinary it combines process management and optimization through tools. These tools historically perform their roles well, but companies are now in a very competitive linked environment and must to behave differently. In my work I have stated firstly why would these areas could be beneficial to each other. The next part focused, what is the relationship with the life-cycle process for BPM and how it fits into the life-cycle services in SOA. Finally, I analyzed the current state mapping of BPMN, the most common notation for expressing processes in BPM, to BPEL. BPEL describes a process, but it is expressed as a programmatic sequential process, which is also executed in digital form. At work I have examined the role of the new version of the BPMN notation 2.0.

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Dutt, Hephzibah Darshni. "Big cheap mysticism postmodernism and theology in Erik Ehn's The saint plays /." Bowling Green, Ohio : Bowling Green State University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=bgsu1214194614.

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Gevros, Panagiotis. "Congestion control mechanisms for scalable bandwidth sharing." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249696.

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Omozuwa, Edosa Victor. "L'Edo : approches phonologique, acoustique et perceptuelle du système phonémique et du système tonémique." Besançon, 1987. http://www.theses.fr/1987BESA1005.

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Schmidt, Dawin. "A Security and Privacy Audit of KakaoTalk’s End-to-End Encryption." Thesis, KTH, Skolan för elektro- och systemteknik (EES), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-196360.

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End-to-end encryption is becoming a standard feature in popular mobile chat appli-cations (apps) with millions of users. In the two years a number of leading chat apps have added end-end encryption features including LINE, KakaoTalk, Viber, Facebook Messenger, and WhatsApp.However, most of these apps are closed-source and there is little to no independent ver-iﬁcation of their end-to-end encryption system design. These implementations may be a major concern as proprietary chat apps may make use of non-standard cryptographic algorithms that may not follow cryptography and security best practices. In addition, governments authorities may force chat app providers to add easily decryptable export-grade cryptography to their products. Further, mainstream apps have a large attack surface as they oﬀer a variety of features. As a result, there may be software vulnera-bilities that could be exploited by an attacker in order to compromise user’s end-to-end privacy. Another problem is that, despite being closed-source software, providers often market their apps as being so secure that even the provider is not able to decrypt messages. These marketing claims may be potentially misleading as most users do not have the technical knowledge to verify them.In this Master’s thesis we use KakaoTalk – the most popular chat app in South Korea – as a case study to perform a security and privacy assessment and audit of its “Secure Chat” opt-in end-to-end encryption feature. Also, we examine KakaoTalk’s Terms of Service policies to verify claims such as “[. . . ] Kakao’s server is unable to decrypt the encryption [. . . ]” from a technical perspective.The main goal of this work is to show how various issues in a product can add up to the potential for serious attack vectors against end-to-end privacy despite there being multiple layers of security. In particular, we show how a central public-key directory server makes the end-to-end encryption system vulnerable to well-known operator-site man-in-the-middle attacks. While this naive attack may seem obvious, we argue that (KakaoTalk) users should know about the strength and weaknesses of a particular design in order to make an informed decision whether to trust the security of a chat app or not.
End-to-end kryptering är en allt mer vanligt förekommande funktionalitet bland populära mobila chatttjänster (händanefter appar) med miljontals användare. Under de två senaste åren har många ledande chattappar, bland annat LINE, KakaoTalk, Viber, Facebook Messenger, och WhatsApp, börjat använda end-to-end kryptering. Dock så är de ﬂesta av dessa appar closed-source och det ﬁnns begränsad, eller ingen, fristående granskning av systemdesignen för deras end-to-end kryptering. Dessa implementationer kan innebära en stor risk då proprietära chattappar kan använda sig av kryptograﬁska algoritmer som inte följer best practice för säkerhet eller kryptograﬁ. Vidare så kan statliga myndigheter tvinga de som tillhandahåller chattappar att använda lättdekrypterad export-grade kryptograﬁ för sina produkter. Lägg till det att de ﬂesta vanliga appar har många ytor som kan attackeras, till följd av all funktionalitet de erbjuder. Som ett resultat av detta ﬁnns en risk för mjukvarubrister som kan utnyttjas av en hackare för att inkräkta på en användares end-to-end integritet. Ytterligare ett problem är att trots att det är closed-source mjukvara så marknadsför ofta appleverantörerna sina appar som att vara är så säkra att inte ens leverantörerna själva kan dekryptera användarnas meddelanden. Det som hävdas i marknadsföringen riskerar vara missledande eftersom de ﬂesta användarna inte har den tekniska kunskap som krävs för att kunna veriﬁera att det som hävdas är sant. I den här Master-uppsatsen använder vi KakaoTalk – den mest populära chattappen i Sydkorea – som en fallstudie för att granska och bedömma säkerhetens- och integritets-aspekterna hos deras valbara “Secure Chat” med end-to-end krypteringsfunktionalitet. Vi granskar även KakaoTalk’s användarvillkor för att kunna veriﬁera påståenden som att “[. . . ] Kakao’s server is unable to decrypt the encryption [. . . ]” från ett tekniskt perspektiv. Det huvudsakliga syftet med denna studien är att belysa hur olika brister i en produkt sammantagna kan skapa en risk för allvarliga vektorattacker mot end-to-end integriteten även fast det ﬁnns ﬂera skyddslager. Mer speciﬁkt visar vi hur en central katalogserver för public-keys gör end-to-end krypteringssystemet sårbart mot välkända operator-site man-in-the-middle-attacker. Trots att denna naiva typ av attack kan verka uppenbar, argumenterar vi för att (KakaoTalk) användare borde veta om styrkorna och svagheterna med en särskild systemdesign för att kunna göra ett informerat val för om de ska lita på säkerheten hos en chattapplikation eller inte.

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Cabellos, Rafael Johanna Milena. "Aplicación de la guia Pmbok en el desarrollo de un proyecto educativo." Bachelor's thesis, Universidad Ricardo Palma, 2012. http://cybertesis.urp.edu.pe/handle/urp/527.

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This thesis attempts to convey the importance of good project management and the advantages to offer the standard PMBOK. This standard is only a guide to "Best Practices" that does not mean that the knowledge described should always be applied uniformly across all projects: the project management team is responsible for determining what is appropriate for each particular project. Within the thesis developed the following plans and recommendations for each: Plan Scope Management, Plan time management, plan cost management, plan quality management, Plan human resources management, plan communication management, Plan risk management, and Plan procurement management.

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Boman, Maria. "XML/EDI - EDI med XML-format?" Thesis, University of Skövde, Department of Computer Science, 2000. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-422.

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Electronic data interchange (EDI) är en teknik vilken används för att utbyta elektroniska dokument mellan köpare och säljare. Dessa dokument överförs på en strikt elektronisk standardiserad väg, dokumenten kan vara fakturor, beställningsformulär, leveransplaner etc. EDI har funnits i över 25år och är vida spridd över världen. För att använda EDI krävs det stora resurser i form av kapital och kunskap. Små och medelstora företag har ofta inte de resurser som krävs för att kunna använda EDI.

Nya tekniker utvecklas ständigt. Extensibel Markup Language (XML) är en ny teknik vilken är avsedd att användas främst på Internet. XML delar upp dokumenten med hjälp av etiketter vilket hjälper läsaren att identifiera innehållet i dokumenten. XML har väckt EDI-samhällets intresse då XML anses ha kapaciteten att kunna användas som ett EDI-format samtidigt som XML är Internetanpassat vilket betyder att EDI enklare skulle kunna användas på Internet.

I mitt examensarbete har jag utrett om EDI-användande företag avser använda XML/EDI. Jag har genomfört intervjuer för att besvara problemformuleringen. Resultaten jag kommit fram till är att företagen avser använda XML/EDI om en ordentlig standard blir framtagen. Företagen är dessutom positivt inställda till XML/EDI samt Internetbaserad EDI. Anledningen till den positiva inställningen är främst att XML/EDI samt Internetbaserad EDI skulle innebära lägre kostnader vilket i sin tur skulle innebära att även små och medelstora företag skulle kunna använda tekniken.

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Tapia, Aguilar María Dolores. "Análisis de encuesta de clima laboral ETN-Turistar 2013." Tesis de Licenciatura, Universidad Autónoma del Estado de México, 2015. http://hdl.handle.net/20.500.11799/99999.

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El presente informe que se presenta a continuación es el resultado de la aplicación de una encuesta y el análisis de un clima laboral en la empresa con el giro del autotransporte denominada ETN–Turistar mostrando sus características, tipos, instrumentos de medición, así como también su importancia del uso de esta técnica dentro de la empresa. Una de las principales funciones que tiene el clima laboral es el de dar a conocer los aspectos que influye en el comportamiento de los colaboradores, el grado de compromiso, aptitudes y actitudes, así también por diferentes variables como el ambiente físico, entre otros. Este trabajo se realizó con el propósito de profundizar nuestros conocimientos en la aplicación e importancia del clima laboral dentro de una organización, a la vez proponer soluciones a problemas laborales. Además hay que considerar que es la primera vez que se realiza una encuesta de clima laboral en ETN-Turistar por lo que se le dará seguimiento para la mejora de cada área que conforman a esta organización.

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Schunck, Volker. "Ein Leben und ein Sein." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-87109.

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Li, Jizhizi. "End-to-end Animal Matting." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/22897.

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Image matting is a widely studied low-level vision problem that aims to provide a detailed foreground alpha matte from a single image, benefiting a wide range of downstream applications. However, most of the prevalent matting models are requiring extra manual intervention such as trimap or scribble. Besides, the lack of large-scale real-world annotated data has also caused poor generalizability in learned deep models. In this paper, we propose a novel end-to-end matting method called GFM along with a real-world, high-quality, category-wised animal matting dataset called AM-2k to address the above issues. The proposed end-to-end matting model GFM is short for Glance and Focus Matting Network, aims to conduct simultaneously trimap generation and matting by sharing one encoder and going through different decoders in separate branches. The design of GFM can help extract local and global information within one stage training process. Without the need for any extra input, GFM surpasses the previous state-of-the-art in performance on all evaluation metrics. Our proposed AM-2k consists of 20 categories mammals animals and 200 high-quality image for each category. We manually generate accurate mattes for each of them. Based on this dataset, we also set up three evaluation tracks, MIX-Track, DA-Track and CW-Track which can benefit the research on end-to-end matting, trimap-based matting, domain adaptation for matting and few shot learning. Extensive experiments and comprehensive analysis are performed on the AM-2k dataset to validate the effectiveness of GFM and its superiority over representative state-of-the-art methods. Various visual results can be found in Chapter 4 and Appendix.

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Харенко, Олександр Олександрович. "Програмна реалізація адаптивного навчання по напряму Front-end". Магістерська робота, Київський національний університет технологій та дизайну, 2021. https://er.knutd.edu.ua/handle/123456789/18045.

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Даний дипломний проект представляє собою автономну, інтерактивну онлайн-систему навчання по веб-розробці, а саме по одній з її частин front-end. Проект буде онлайн-курсом, де кожен бажаючий, не залежно від віку, може навчитися всього, що стосується такої важливої частини веб-розробки, як front-end. Все, що потрібно від користувача даного проекту, це тільки терпіння і бажання вчитися й пізнавати нове.
This diploma project is an autonomous, interactive online learning system for web development, namely one of its parts front-end. The project will be an online course where everyone, regardless of age, can learn everything related to such an important part of web development as front-end. All that is required from the user of this project is only patience and desire to learn and learn something new.

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Adams, René [Verfasser]. "Systemkonzeption und Entwicklung eines Mixed-Signal Front-End-Chips für ein maritimes S-Band Phased Array Radar System / René Adams." München : Verlag Dr. Hut, 2017. http://d-nb.info/1149579358/34.

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Schneider, Ulrich Johannes. "Martin Stuber, Stefan Hächler and Luc Lienhard (eds), Hallers Netz. Ein europäischer Gelehrtenbriefwechsel zur Zeit der Aufklärung, Basel 2005 (Rezension)." Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-161442.

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Haller was, by any standard, a very prolific writer, not only of letters. He published 24 books in 50 volumes, many of which he reworked for second editions; he wrote 450 essays, 9000 book reviews, and edited another 52 volumes. Of his letters exchanged with 1139 male and 50 female correspondents, close to 17,000 have survived.

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Schneider, Ulrich Johannes. "Martin Stuber, Stefan Hächler and Luc Lienhard (eds), Hallers Netz. Ein europäischer Gelehrtenbriefwechsel zur Zeit der Aufklärung, Basel 2005 (Rezension)." Cambridge Univ. Press, 2008. https://ul.qucosa.de/id/qucosa%3A13184.

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Анотація:

Haller was, by any standard, a very prolific writer, not only of letters. He published 24 books in 50 volumes, many of which he reworked for second editions; he wrote 450 essays, 9000 book reviews, and edited another 52 volumes. Of his letters exchanged with 1139 male and 50 female correspondents, close to 17,000 have survived.

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Fahlaoui, Tarik. "Réduction de modèles et apprentissage de solutions spatio-temporelles paramétrées à partir de données : application à des couplages EDP-EDO." Thesis, Compiègne, 2020. http://www.theses.fr/2020COMP2535.

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On s’intéresse dans cette thèse à l’apprentissage d’un modèle réduit précis et stable, à partir de données correspondant à la solution d’une équation aux dérivées partielles (EDP), et générées par un solveur haute fidélité (HF). Pour ce faire, on utilise la méthode Dynamic Mode Decomposition (DMD) ainsi que la méthode de réduction Proper Orthogonal Decomposition (POD). Le modèle réduit appris est facilement interprétable, et par une analyse spectrale a posteriori de ce modèle on peut détecter les anomalies lors de la phase d’apprentissage. Les extensions au cas de couplage EDP-EDO, ainsi qu’au cas d’EDP d’ordre deux en temps sont présentées. L’apprentissage d’un modèle réduit dans le cas d’un système dynamique contrôlé par commutation, où la règle de contrôle est apprise à l’aide d’un réseau de neurones artificiel (ANN), est également traité. Un inconvénient de la réduction POD, est la difficile interprétation de la représentation basse dimension. On proposera alors l’utilisation de la méthode Empirical Interpolation Method (EIM). La représentation basse dimension est alors intelligible, et consiste en une restriction de la solution en des points sélectionnés. Cette approche sera ensuite étendue au cas d’EDP dépendant d’un paramètre, et où l’algorithme Kernel Ridge Regression (KRR) nous permettra d’apprendre la variété solution. Ainsi, on présentera l’apprentissage d’un modèle réduit paramétré. L’extension au cas de données bruitées ou bien au cas d’EDP d’évolution non linéaire est présentée en ouverture
In this thesis, an algorithm for learning an accurate reduced order model from data generated by a high fidelity solver (HF solver) is proposed. To achieve this goal, we use both Dynamic Mode Decomposition (DMD) and Proper Orthogonal Decomposition (POD). Anomaly detection, during the learning process, can be easily done by performing an a posteriori spectral analysis on the reduced order model learnt. Several extensions are presented to make the method as general as possible. Thus, we handle the case of coupled ODE/PDE systems or the case of second order hyperbolic equations. The method is also extended to the case of switched control systems, where the switching rule is learnt by using an Artificial Neural Network (ANN). The reduced order model learnt allows to predict time evolution of the POD coefficients. However, the POD coefficients have no interpretable meaning. To tackle this issue, we propose an interpretable reduction method using the Empirical Interpolation Method (EIM). This reduction method is then adapted to the case of third-order tensors, and combining with the Kernel Ridge Regression (KRR) we can learn the solution manifold in the case of parametrized PDEs. In this way, we can learn a parametrized reduced order model. The case of non-linear PDEs or disturbed data is finally presented in the opening

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Rangarajan, Vinod K. (Vinod Kashyap) 1975. "End-to-end connectivity across firewalls." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/47623.

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Thesis (S.B. and M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1998.
Includes bibliographical references (leaves 53-54).
by Vinod K. Rangarajan.
S.B.and M.Eng.

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35

Chan, William. "End-to-End Speech Recognition Models." Research Showcase @ CMU, 2016. http://repository.cmu.edu/dissertations/723.

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For the past few decades, the bane of Automatic Speech Recognition (ASR) systems have been phonemes and Hidden Markov Models (HMMs). HMMs assume conditional indepen-dence between observations, and the reliance on explicit phonetic representations requires expensive handcrafted pronunciation dictionaries. Learning is often via detached proxy problems, and there especially exists a disconnect between acoustic model performance and actual speech recognition performance. Connectionist Temporal Classification (CTC) character models were recently proposed attempts to solve some of these issues, namely jointly learning the pronunciation model and acoustic model. However, HMM and CTC models still suffer from conditional independence assumptions and must rely heavily on language models during decoding. In this thesis, we question the traditional paradigm of ASR and highlight the limitations of HMM and CTC models. We propose a novel approach to ASR with neural attention models and we directly optimize speech transcriptions. Our proposed method is not only an end-to- end trained system but also an end-to-end model. The end-to-end model jointly learns all the traditional components of a speech recognition system: the pronunciation model, acoustic model and language model. Our model can directly emit English/Chinese characters or even word pieces given the audio signal. There is no need for explicit phonetic representations, intermediate heuristic loss functions or conditional independence assumptions. We demonstrate our end-to-end speech recognition model on various ASR tasks. We show competitive results compared to a state-of-the-art HMM based system on the Google voice search task. We demonstrate an online end-to-end Chinese Mandarin model and show how to jointly optimize the Pinyin transcriptions during training. Finally, we also show state-of-the-art results on the Wall Street Journal ASR task compared to other end-to-end models.

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36

Le, BeEm V. "Distributed and end-to-end testing." Thesis, Monterey, California : Naval Postgraduate School, 2009. http://edocs.nps.edu/npspubs/scholarly/theses/2009/Dec/09Dec%5FLe.pdf.

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Thesis (M.S. in Systems Engineering Management)--Naval Postgraduate School, December 2009.
Thesis Advisor: Huynh, Thomas V. Second Reader: Barrera, Raymond. "December 2009." Description based on title screen as viewed on January 26, 2010. Author(s) subject terms: distributed, End-to-End, combat systems, C4I Systems, pay-per-test, Goal Programming (GP), Distributed Engineering Plant (DEP), E2E Lab, PMW, PEO C4I, NAVSEA, SPAWAR. Includes bibliographical references (p. 53-54). Also available in print.

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37

Koga, Paula Suemy Landi. "Expansão do setor sucroenergético e avaliação socioeconômica da produção de cana de açúcar na região noroeste do estado de São Paulo /." Ilha Solteira, 2017. http://hdl.handle.net/11449/151330.

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Orientador: Mario Luiz Teixeira de Moraes
Resumo: A forte expansão do setor sucroenergético na região noroeste, em uma região caracterizada pela pecuária e fruticultura, motivou a realização deste estudo para avaliar a expansão da cana de açúcar e os impactos sociais e econômicos, em municípios pertencentes aos Escritórios de Desenvolvimento Rural de Fernandópolis, Jales e Votuporanga, localizados na região noroeste do Estado de São Paulo. Foram entrevistados representantes das prefeituras dos municípios com usinas, para analisar os impactos (socioeconômicos e ambiental) ocasionados após a instalação da agroindústria da cana. Foram levantados e analisados os seguintes indicadores socioeconômicos: População residente urbana e rural, o Índice da Federação das Indústrias do Estado do Rio de Janeiro- FIRJAN de Desenvolvimento Municipal (IFDM), Produto Interno Bruto per capita (PIB per capita), o Índice de Gini e vínculo empregatício. Para a análise da viabilidade econômica do cultivo da cana de açúcar foram determinados os custos, a lucratividade, o Valor Presente Líquido (VPL), a Taxa Interna de Retorno (TIR) e o Período de Recuperação do Capital (Payback Period). Assim, observou-se que as principais mudanças positivas foram geração de empregos, aumento de renda da população, movimentação do comércio local e arrecadação de impostos. Problemas na área ambiental com maior toxidez nas outras culturas através da deriva de produtos fitossanitários, aumento da população da mosca de estábulos, diminuição de áreas de plantio de grãos e... (Resumo completo, clicar acesso eletrônico abaixo)
Doutor

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38

Sládková, Pavlína. "Využití IT nástrojů při organizaci ESN CZ National Platform." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-124771.

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Student organisations offer many opportunities to try out numbers of real projects with real budgets and deadlines. However, the high turnover of members in these organizations and imperfect knowledge transfer between the generations slow down the improvements and realization of different projects. This diploma thesis describes planning, preparation, implementation and evaluation of a specific project within the Erasmus Student Network Czech Republic (ESN CZ) which aims to meet representatives of all student organizations involved in ESN CZ. Through the description of the event, introduction to project management and their interconnection reader gets a comprehensive view on the issue of organizing the ESN CZ National Platform (ESN CZ NP). A following review of the IT tools available on the market, their evaluation and selection of a few specific applications offer options in IT project management support. Selected IT tools are demonstrated in real situations, including the recommendation for other useful functionalities. The diploma thesis is dedicated to project management from the perspective of a student organization dealing with the preparation of specific event in the context of the general phases of project management, creating manual for future coordinators ESN CZ NP.

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39

Everett, Katharine More. "Eden." Cleveland State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=csu1589227367791853.

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40

Scholz, Martin. "EDEN." Universitätsbibliothek Leipzig, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-221593.

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41

Lindgren, Sandra, and Erik Pettersson. "Elektronisk Handel : Framtagning av två implementeringsmodeller." Thesis, University of Gävle, Faculty of Engineering and Sustainable Development, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-6974.

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42

Koga, Paula Suemy Landi [UNESP]. "Expansão do setor sucroenergético e avaliação socioeconômica da produção de cana de açúcar na região noroeste do estado de São Paulo." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/151330.

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Made available in DSpace on 2017-08-18T20:06:13Z (GMT). No. of bitstreams: 1 koga_psl_dr_ilha.pdf: 4032090 bytes, checksum: 39b750b66f0a0958e26aaf3aa61d254e (MD5) Previous issue date: 2017-06-30
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
A forte expansão do setor sucroenergético na região noroeste, em uma região caracterizada pela pecuária e fruticultura, motivou a realização deste estudo para avaliar a expansão da cana de açúcar e os impactos sociais e econômicos, em municípios pertencentes aos Escritórios de Desenvolvimento Rural de Fernandópolis, Jales e Votuporanga, localizados na região noroeste do Estado de São Paulo. Foram entrevistados representantes das prefeituras dos municípios com usinas, para analisar os impactos (socioeconômicos e ambiental) ocasionados após a instalação da agroindústria da cana. Foram levantados e analisados os seguintes indicadores socioeconômicos: População residente urbana e rural, o Índice da Federação das Indústrias do Estado do Rio de Janeiro- FIRJAN de Desenvolvimento Municipal (IFDM), Produto Interno Bruto per capita (PIB per capita), o Índice de Gini e vínculo empregatício. Para a análise da viabilidade econômica do cultivo da cana de açúcar foram determinados os custos, a lucratividade, o Valor Presente Líquido (VPL), a Taxa Interna de Retorno (TIR) e o Período de Recuperação do Capital (Payback Period). Assim, observou-se que as principais mudanças positivas foram geração de empregos, aumento de renda da população, movimentação do comércio local e arrecadação de impostos. Problemas na área ambiental com maior toxidez nas outras culturas através da deriva de produtos fitossanitários, aumento da população da mosca de estábulos, diminuição de áreas de plantio de grãos e pastagens, e desgaste das rodovias devido ao excesso peso do tráfego de caminhões. Os indicadores sociais mostraram que a população urbana expandiu para todos os municípios dos EDRs de Votuporanga e de Jales (com exceção do município de Aparecida D’Oeste), e ocorreu uma redução no IFDM consolidado para os três EDRs estudados. Em relação ao PIB per capita, no geral notou-se que a média dos municípios com usinas no EDR de Votuporanga se destacaram com crescimento econômico de 74,97%, no entanto nos EDRs de Fernandópolis e Jales apresentaram índices inferiores a 2,29%. O COT na implantação do canavial foi de R$6.772,82/ha e nos custos de produção dos cinco cortes, observou-se que a operação com CCT apresentou o maior dispêndio. A análise econômica mostrou lucratividade em todos os cortes para o COT e para os três primeiros cortes para o CT, considerando o preço médio de R$84,15 a tonelada, e produtividade média variando de 106,5t/ha (1º corte), a 65,77t/ha (5º corte). O capital investido na produção de cana para indústria retorna ao fornecedor no 3º corte (CT) e no 2º corte (COT), os VPL foram positivos e as TIR para ambos os custos foram maiores que o custo do capital. A produção de cana de açúcar para indústria na região noroeste paulista apresenta resultados economicamente favoráveis, mas o produtor precisa exercer uma gestão eficiente do seu negócio, gerenciamento dos custos que lhe permita tomar decisões baseadas nos mesmos, principalmente na renovação dos canaviais em que o investimento na atividade é grande. Os resultados socioeconômicos obtidos não permitem afirmar que os avanços nos indicadores estudados se devem a presença de usinas em alguns municípios.
The purpose of this study was to evolute the expansion of the sugarcane and its social and economic impacts, in municipalities of the Rural Development Offices from Fernandópolis, Jales and Votuporanga, located in northwest of the State of São Paulo. This study was motived by the Strong expansion of the sugar energy sector in a region normally characterized by catlle raising and fruit growing. The City Halls of those Municipalities with sugarcane mills in theseRural Developmente Offices (EDRs- Escritorio de Desenvolvimento Rural) were interviewed to analyse the socioeconomic and environmental impacts caused after the installation of sugarcane industry. The following socioeconomic indicators were collected and analyzed: urban and rural residente population, the index of Federation of the Industries from the State Rio de Janeiro (FIRJAN), Municipal Development (IFDM), Gross Domestic product per capita (PIB per capita), Gini Index and employment relationship. Analysis was gathered on the economic feasibility of sugarcane cultivation, the costs, profitability, Net Present Value (VPL- Valor Presente Líquido), Internal Rate of Return (TIR- Taxa Interna de Retorno) and Payback Period The main positive changes were the generation of jobs, the increase of population’s income, the movement of local commerce and the collection of taxes. Problems in environmental area with greater toxicity through the drift of phytosanitary products, increase of the fly population of the stables, reduction of planting grain area and grazing areas and wear and precariousness roads due to the excess weight of trucks traffic. The social indicators showed that the urban population expanded to all EDR cities from Votuporanga and Jales (except Aparecida D’Oeste city), and there was a reduction in consolidated IFDM for the three EDRs studied. Regarding GDP per capita (PIB), in general it was noted the average of municipalities with sugar cane plants in EDR from Votuporanga stood out with economic growth of 74,97%, however EDR from Fernandópolis and Jales presented indexes lower than 2,29%. COT in the planting of the sugar cane fields was R$6.772,82/ha and in the production costs of five cuts, the operation with CCT presented the highest expenditure. The economic analysis showed profitability in all cuts to TOC and to the first three cuts to CT, considering the average price of R$84,15 per ton and an average productivity ranging from 106,5t/ha (1st cut) to 65,77 t/ha (5th cut). The capital invested in the production of sugar cane for industry returns to the supplier in the 3rd cut (CT) and in the 2nd cut (COT), the VPL were positive and the TIR for both costs were higher than the capital cost. The production of sugar cane for industry in northwest of São Paulo State presents economically favorable results, but the producer needs to exercise an efficient management of his business, cost management that allows him to make decisions based on them, especially in the sugar cane fields renovation, where the investment in the activity is big. The socioeconomic results obtained do not allow to affirm the advances in the indicators studied are due to the presence of sugarcane plants in some municipalities.

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43

Ullman, Jeffrey Layton. "The chemical behavior of estrone and 17beta-estradiol in the environment." Diss., Texas A&M University, 2003. http://hdl.handle.net/1969.1/5924.

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The endogenous hormones estrone and 17ÃÂ²-estradiol support vertebrate growth and development, but slight increases above ambient concentrations may paradoxically induce endocrine disruption, leading to increased frequencies of reproductive disorders and cancer in humans and wildlife. Livestock excrete estrogenic compounds which can lead to surface and groundwater contamination. Limited information exists concerning estrogen fate and transport, as exposure concerns have recently arisen. This study examined the chemical behavior of estrone and 17ÃÂ²-estradiol with the goal of elucidating manure management principles applicable to animal feeding operations (AFOs). Both compounds indicated that they are susceptible to physicochemical and biological decomposition. Photolysis yielded 27- and 35-day half-lives for estrone and 17ÃÂ²-estradiol at pH 7, respectively, based on test conditions. 17ÃÂ²-estradiol photolysis exhibited a slight pH-dependent behavior. Mineralization produced half-lives ranging from 7 to 15 days for estrone and 3 to 7 days for 17ÃÂ²-estradiol. Indigenous microbial populations did not demonstrate a lag phase and therefore appeared to have been well acclimated to degrading these compounds. Anaerobic lagoon supplements did not affect mineralization rates. The compounds had partition coefficients ranging from 2 to 4.4 mL g-1, depending on soil characteristics. Estrone and 17ÃÂ²-estradiol had a higher absorptivity to soils with greater clay content and organic matter. Once sorbed, binding appeared largely irreversible with minimal desorption. Column experiments detected no estrone in the leachate for the finer textured soils, while estrone had completely migrated through the loamy fine sand after 7 pore volumes. Hypothetical scenarios, simulated using HYDRUS-1D, evaluated the combined effects of soil texture and the values obtained for sorption and mineralization on leaching. Model results indicated rapid leaching in loamy sand, while sandy clay loam and clay yielded significantly slower estrone and 17ÃÂ²-estradiol movement with concentrations 1 to 3 orders of magnitude lower. Data suggest that estrogens applied to sandy soil may leach and contaminate groundwater, especially in the presence of shallow water tables. Sandy clay loam and clay likely present minimal risk for subsurface mobility, but simulated accumulation near the soil surface may promote transport via overland flow. Sound manure management practices will likely reduce off-site transport of estrogens originating from AFOs.

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44

Toraason, Peter. "Creating the Image of Community: Urban redevelopment and public housing in Cincinnati’s West End." University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1212170601.

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45

Stel, Gerwin Cheragie Megol Miltenburg-Miedema Freda. "Een PET/CT, wat is stap 2? een onderzoek naar de factoren die een rol spelen bij een succesvolle implementatie van een PET/CT /." Groningen : Groningen : HG, Medisch Beeldvormende en Radiotherapeutische Technieken ; Hanzehogeschool Groningen [Host], 2007. http://scripties.hanze.nl/2007/SAGZ/MBRT/20.pdf.

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46

Chaudry, Kashif, and Elma Karadza. "End-to-End Application Billing in 3G." Thesis, Linköping University, Department of Science and Technology, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1654.

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We have 3G on the doorstep but nothing seems to attract ordinary people to this technology. To attract the mass market the telecom industry must show something beyond high bit rates. They must show how ordinary people can take advantage of this new technology. This is done by showing the possibilities of the new technology and by demonstrating applications that it will handle. The telecom industry must convince the telecom operators to invest in this technology and the only thing that matters to them is how much revenue they can make by adopting the upcoming technology.

To convince the operators industry must show how the operators can charge for the new types of applications that will be introduced soon. This is the main reason why this Master's Thesis has been conducted. The purpose of this thesis is to provide a demonstration to Ericsson's 3G lab in Katrineholm in the form of an IP application with a billing solution. This thesis describes the migration from 1G to 3G and examines existing and future billing strategies as well.

The IP application is an application that uses progressive streaming in order to stream multimedia content to a PDA connected to a 3G phone. This application is platform independent because it is placed on leading Web servers, Apache and IIS.

The billing application consists of a number of steps. The first step is logging, which is performed by the Web server on which the streaming application is placed. The second step, processing and billing, is performed in the BGw, which is Ericsson's mediation tool, and the SQL server.The third step is displaying the bill, which is done by using ASP to create an active HTML page.

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47

Holmström, Maria. "End-to-end monitoring of mobile services." Thesis, Linköping University, Department of Electrical Engineering, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1671.

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The growing market of mobile services through SMS, MMS, WAP and soon also for 3G protocols, requires efficient test methods to ensure that the customers get what they are paying for and in a reasonable time. Preferably, these tests should be done automatically and come as close to real conditions as possible. It would be valuable to be able to make tests from end to end, i.e. requesting and receiving the mobile services on a real mobile phone and combine that with a system that controls and evaluates the tests.

This thesis presents a solution to how the part of an end-to-end monitoring system for mobile services that runs on a mobile phone can be designed and implemented. The phone is made to interpret commands from a control process on a remote server and turn them into mobile service requests in a proper format (e.g. SMS or MMS). When it receives the reply from a mobile service provider, it forwards the relevant result information to the control process.

The monitoring system is based on Symbian OS, an operating system developed to suit handheld devices like mobile phones. The current implementation supports tests for SMS and MMS services.

The system is to be used by mobile operators or other providers of mobile services, which want to test and monitor their services.

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48

Lazar, Mihai. "Empirical modeling of end-to-end jitter." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0019/MQ58472.pdf.

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49

Brown, Ian. "End-to-end security in active networks." Thesis, University College London (University of London), 2001. http://discovery.ucl.ac.uk/3882/.

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Active network solutions have been proposed to many of the problems caused by the increasing heterogeneity of the Internet. These ystems allow nodes within the network to process data passing through in several ways. Allowing code from various sources to run on routers introduces numerous security concerns that have been addressed by research into safe languages, restricted execution environments, and other related areas. But little attention has been paid to an even more critical question: the effect on end-to-end security of active flow manipulation. This thesis first examines the threat model implicit in active networks. It develops a framework of security protocols in use at various layers of the networking stack, and their utility to multimedia transport and flow processing, and asks if it is reasonable to give active routers access to the plaintext of these flows. After considering the various security problem introduced, such as vulnerability to attacks on intermediaries or coercion, it concludes not. We then ask if active network systems can be built that maintain end-to-end security without seriously degrading the functionality they provide. We describe the design and analysis of three such protocols: a distributed packet filtering system that can be used to adjust multimedia bandwidth requirements and defend against denial-of-service attacks; an efficient composition of link and transport-layer reliability mechanisms that increases the performance of TCP over lossy wireless links; and a distributed watermarking servicethat can efficiently deliver media flows marked with the identity of their recipients. In all three cases, similar functionality is provided to designs that do not maintain end-to-end security. Finally, we reconsider traditional end-to-end arguments in both networking and security, and show that they have continuing importance for Internet design. Our watermarking work adds the concept of splitting trust throughout a network to that model; we suggest further applications of this idea.

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50

Maaz, Khan. "EVASIVE INTERNET PROTOCOL: END TO END PERFORMANCE." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1308179859.

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