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Статті в журналах з теми "Early colorectal Cancer"

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Автор: Grafiati

Опубліковано: 14 березня 2023

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1

Li, J. "The Experiences of Early Detection, Early Diagnosis and Early Treatment of Cancer in Rural Areas of China." Journal of Global Oncology 4, Supplement 2 (October 1, 2018): 49s. http://dx.doi.org/10.1200/jgo.18.60300.

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Background: The cancers of the lung, liver, stomach, esophagus, colorectum and nasopharynx account for more than 70% of the causes of cancer death, making them the major cancer burdens in China. The early detection and treatment of cancers including lung, liver, stomach, esophagus, colorectum and nasopharynx was supported by the central government special financial transfer payment in the rural areas in 2006-2017. Aim: To improve the efficiency of early diagnosis and early treatment to reduce cancer mortality and incidence in the population in China. Methods: Cancer screening methods developed by Group of Expert Committee of Cancer Foundation of China were used, including digestive tract endoscopy for stomach and esophageal and colorectal cancer, LDCT for lung cancer, AFP and abdominal ultrasound for liver cancer, EB virus antibody detection and nasal endoscopy for nasopharyngeal carcinoma. Results: Among the cancers of lung, liver, stomach, esophagus, colorectum and nasopharynx, the screening high risk population were 55,363; 126,443; 103,3036; 1,425,642; 252,911; and 79,726 respectively; and the screening detection rates of precancerous lesions and cancer were 0.62%, 0.66%, 0.87%, 1.62%, 5.29% and 0.49% respectively; and the early diagnosis rates were 47.80%, 60.86%, 71.24%, 73.38%, 91.85% and 64.43% respectively; and the treatment rates were 83.28%, 90.33%, 87.94%, 82.91%, 94.04% and 95.88% respectively. Conclusion: The programs for early detection and early treatment of colorectal cancer and esophageal cancer demonstrated a promising benefit, which should be generalized to broad population implementation.

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2

Hong, Seung Wook, and Jeong-Sik Byeon. "Endoscopic diagnosis and treatment of early colorectal cancer." Intestinal Research 20, no. 3 (July 30, 2022): 281–90. http://dx.doi.org/10.5217/ir.2021.00169.

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Early colorectal cancer refers to cancer in the colorectum that is confined to the mucosa or submucosa and does not invade the muscularis propria, irrespective of lymph node or distant metastasis. As the number of persons undergoing screening colonoscopy increases, the proportion of patients diagnosed with precancerous colorectal lesions and early colorectal cancer also increases. In the last decade, innovative optical technologies for endoscopic diagnosis have been introduced and endoscopic treatment techniques such as endoscopic submucosal dissection have provided major breakthroughs in the management of early colorectal cancer. With these remarkable developments, endoscopic treatment has established itself as an alternative to surgical resection in the treatment of early colorectal cancer. This review will discuss the endoscopic diagnosis and treatment of early colorectal cancer. Furthermore, the unmet needs in this field and the latest research addressing those issues will be summarized.

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3

Smith, D., M. Ballal, R. Hodder, G. Soin, SN Selvachandran, and D. Cade. "Symptomatic Presentation of Early Colorectal Cancer." Annals of The Royal College of Surgeons of England 88, no. 2 (March 2006): 185–90. http://dx.doi.org/10.1308/003588406x94904.

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INTRODUCTION It is believed that increased detection of earlier stage colorectal cancer can only be achieved by screening asymptomatic individuals. We describe a referral pathway for a symptomatic population which achieves a 30% Dukes' A detection rate. PATIENTS AND METHODS From October 1999, 4253 patients with distal colonic symptoms, referred by general practitioners, completed a patient consultation questionnaire (PCQ) linked to a computerised record. A weighted numerical score (WNS) was derived for each patient. Patients underwent flexible sigmoidoscopy, a diagnostic outcome was recorded and later Dukes' stage appended. Early and advanced colorectal cancers were separated and PCQ derived symptom profiles compared. Chi-square, Fisher exact, Student's t-test and logistic regression were used for statistical analysis. RESULTS A total of 183 patients had cancer, 55 (30%) were Dukes' A early colorectal cancers, 112 were advanced colorectal cancers (Dukes' B–D) and 16 could not be staged. Early colorectal cancers had significant symptoms and comparable profile to advanced colorectal cancers. The tendency in advanced colorectal cancers was towards greater symptom prevalence for only a few primary and systemic symptoms, as reflected by a higher WNS of 75 (P = 0.001) CONCLUSIONS Early colorectal cancers do have significant symptoms which can easily be captured by a PCQ and objective scoring tool in the secondary care setting. Detection of these cancers has the potential to improve survival.

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4

Decosse, Jerome J. "Early cancer detection colorectal cancer." Cancer 62, S1 (October 15, 1988): 1787–90. http://dx.doi.org/10.1002/1097-0142(19881015)62:1+<1787::aid-cncr2820621317>3.0.co;2-i.

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5

Jeong, Mo Ah, and Hyoun Woo Kang. "Early-onset Colorectal Cancer." Korean Journal of Gastroenterology 74, no. 1 (2019): 4. http://dx.doi.org/10.4166/kjg.2019.74.1.4.

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6

Nfonsam, Valentine, Emily Wusterbarth, Amanda Gong, and Priyanka Vij. "Early-Onset Colorectal Cancer." Surgical Oncology Clinics of North America 31, no. 2 (April 2022): 143–55. http://dx.doi.org/10.1016/j.soc.2021.11.001.

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7

Blum, H. E. "Colorectal cancer: Future population screening for early colorectal cancer." European Journal of Cancer 31, no. 7-8 (July 1995): 1369–72. http://dx.doi.org/10.1016/0959-8049(95)00215-5.

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8

Wang, Ning, Yang Chen, Yuchen Han, Yue Zhao, Yu Liu, Kejian Guo, and Yi Jiang. "Proteomic analysis shows down-regulations of cytoplasmic carbonic anhydrases, CAI and CAII, are early events of colorectal carcinogenesis but are not correlated with lymph node metastasis." Tumori Journal 98, no. 6 (November 2012): 783–91. http://dx.doi.org/10.1177/030089161209800617.

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Aim The aim of the study was to screen the markedly down-regulated proteins in colorectal cancer and analyze their relationship to carcinogenesis, cancer progression and pathological aspects. Methods Proteomic analysis was preformed on six fresh colorectal cancer tissues and paired normal colorectal mucosa by two-dimensional differential gel electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry. Two markedly down-regulated proteins among the proteins, of which the expressions were significantly decreased in colorectal cancer compared to normal mucosa, were confirmed by Western Blot in 12 colorectal cancers. Their relationship to carcinogenesis, cancer progression and pathological aspects of colorectal cancer were analyzed in 64 colorectal cancer and paired normal mucosa, 27 benign polyps, and 20 lymph node metastases by immunohistochemistry. Results Two-dimensional differential gel electrophoresis analysis showed there were 2 protein spots, of which the average abundances decreased 3.62 and 3.76 fold in colorectal cancer compared to normal mucosa, respectively. They were identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry as carbonic anhydrase I and II (CAI and CAII). Validation by Western Blot in 12 colorectal cancers showed there were significantly different expressions of CAI and CAII between colorectal cancer and normal mucosa (P = 0.002 and 0.027, respectively). Immunohistochemistry analysis indicated the expression of CAI and CAII was decreased from normal mucosa to benign polyps, and to colorectal cancer stepwise significantly (P <0.05). However, there were no differences in their expressions between lymph node metastasis and colorectal cancer (P >0.05). There were decreasing trends of CAI and CAII expressions from well to poor differentiation and from stage I or II to stage III or IV, but they were not statistically significant (P >0.05). Conclusions CAI and CAII are necessary enzymes of the colorectum for their normal function. Down-regulations of CAI and CAII are early events of colorectum carcinogenesis. They have no correlations with lymph node metastasis.

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9

O’Reilly, Mary, Anna Linehan, Aleksandar Krstic, Walter Kolch, Kieran Sheahan, Des C. Winter, and Ray Mc Dermott. "Oncotherapeutic Strategies in Early Onset Colorectal Cancer." Cancers 15, no. 2 (January 16, 2023): 552. http://dx.doi.org/10.3390/cancers15020552.

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Early onset colorectal cancer (EOCRC), defined as colorectal cancers in patients aged less than 50 years, is becoming an increasingly common issue, globally. Since 1994, the incidence of this condition has been rising by 2% annually. Approximately one in five patients under 50 years of age diagnosed with colorectal cancer have an underlying genetic predisposition syndrome. The detection of cancer among the other 80% of patients poses a considerable task, as there is no family history to advocate for commencing early screening in this group. Patients with EOCRC have distinct social, spiritual, fertility, and financial needs from their older counterparts that need to be addressed. This review discusses the risk factors associated with the development of EOCRC and current best practice for the management of this disease.

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10

Kitamura, Kazuya, Satoki Nishida, Kazuhito Yamamoto, Daisuke Ichikawa, Kazuma Okamoto, Kiyoshi Sawai, Toshiharu Yamaguchi, and Toshio Takahashi. "Mp Colorectal Cancer Should Be Defined as Early Colorectal Cancer." Tohoku Journal of Experimental Medicine 184, no. 4 (1998): 285–93. http://dx.doi.org/10.1620/tjem.184.285.

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11

Silla, Irene Osorio. "Early-onset colorectal cancer: A separate subset of colorectal cancer." World Journal of Gastroenterology 20, no. 46 (2014): 17288. http://dx.doi.org/10.3748/wjg.v20.i46.17288.

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12

Kudo, Shin-ei, Yuta Kouyama, Yushi Ogawa, Katsuro Ichimasa, Tsuyoshi Hamada, Kazuki Kato, Koki Kudo, et al. "Depressed Colorectal Cancer: A New Paradigm in Early Colorectal Cancer." Clinical and Translational Gastroenterology 11, no. 12 (December 2020): e00269. http://dx.doi.org/10.14309/ctg.0000000000000269.

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13

Yeo, Heather, Doron Betel, Jonathan S. Abelson, Xi E. Zheng, Rhonda Yantiss, and Manish A. Shah. "Early-onset Colorectal Cancer is Distinct From Traditional Colorectal Cancer." Clinical Colorectal Cancer 16, no. 4 (December 2017): 293–99. http://dx.doi.org/10.1016/j.clcc.2017.06.002.

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14

Araki, Yasumi, Hiroki Iwanaga, Akira Okita, Yutaka Ogata, Tatsuhisa Morodomi, Kazuo Shirouzu, Hiroharu Isomoto, and Teruo Kakegawa. "Treatment for Early Colorectal Cancer." Japanese Journal of Gastroenterological Surgery 26, no. 10 (1993): 2532–36. http://dx.doi.org/10.5833/jjgs.26.2532.

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15

Ottó, Szabolcs, János H. Czalbert, Ilona Papp, and Sándor Eckhardt. "Early Detection of Colorectal Cancer." Oncology 47, no. 3 (1990): 209–14. http://dx.doi.org/10.1159/000226818.

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16

Kronborg, Ole. "Screening for Early Colorectal Cancer." World Journal of Surgery 24, no. 9 (September 2000): 1069–74. http://dx.doi.org/10.1007/s002680010146.

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17

Jass, Jeremy R. "Histopathology of Early Colorectal Cancer." World Journal of Surgery 24, no. 9 (September 2000): 1016–21. http://dx.doi.org/10.1007/s002680010152.

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18

Zhu, Guannan, Zijun Wu, Su Lui, Na Hu, and Min Wu. "Advances in Imaging Modalities and Contrast Agents for the Early Diagnosis of Colorectal Cancer." Journal of Biomedical Nanotechnology 17, no. 4 (April 1, 2021): 558–81. http://dx.doi.org/10.1166/jbn.2021.3064.

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Colorectal cancer is one of the most common gastrointestinal cancers worldwide. The mortality rate of colorectal cancer has declined by more than 20% due to the rapid development of early diagnostic techniques and effective treatment. At present, there are many diagnostic modalities available for the evaluation of colorectal cancer, such as the carcinoembryonic antigen test, the fecal occult blood test, endoscopy, X-ray barium meal, computed tomography, magnetic resonance imaging, and radionuclide examination. Sensitive and specific imaging modalities have played an increasingly important role in the diagnosis of colorectal cancer following the rapid development of novel contrast agents. This review discusses the applications and challenges of different imaging techniques and contrast agents applied to detect colorectal cancer, for the purpose of the early diagnosis and treatment of patients with colorectal cancer.

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19

Kim, Min Hyun, Sanghee Park, Nari Yi, Bobae Kang, and In Ja Park. "Colorectal cancer mortality trends in the era of cancer survivorship in Korea: 2000–2020." Annals of Coloproctology 38, no. 5 (October 31, 2022): 343–52. http://dx.doi.org/10.3393/ac.2022.00535.0076.

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Purpose: Korea has implemented an early screening for colorectal cancer since 2004. However, it is not known whether this has translated into improved survival over the years.Methods: We acquired colorectal cancer mortality data from the Cause of Death Statistics in Korea from 2000 to 2020. We characterized the data into year of death, cancer-specific loci, and age group. We analyzed age-standardized mortality rates (ASMR) according to year of death, age group, and primary location to find trends in colorectal cancer mortality over a 20-year period.Results: The crude mortality rate of colorectal cancer increased from 8.78 per 100,000 in 2000 to 17.27 per 100,000 in 2020. The second decade was slower in increments compared to the first decade. ASMR showed a decrease over the second decade after an initial increase in the first decade. The decrease was primarily from the lowering of ASMR for rectosigmoid cancers. Age group analysis showed a lowering of ASMR mainly in the 45–59-year, 60–74-year, and ≥ 75-year age groups; however, 0–29-year and 30–44-year age groups showed generally unchanged ASMR over the total period.Conclusion: After a brief incline of age-specific mortality of colorectal cancers during the early 2000s, colorectal cancer mortality has gradually been decreasing in the past decade. This was mainly due to decreased mortalities in rectosigmoid colon cancers especially in the age groups that were the target of early screening.

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20

Omenukor, K. "Cancer Awareness Campaign and Screening." Journal of Global Oncology 4, Supplement 2 (October 1, 2018): 142s. http://dx.doi.org/10.1200/jgo.18.73900.

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Background and context: Colorectal cancer is the 3rd leading cause of cancer-related mortalities, which can be prevented by early screening. However, inadequate knowledge regarding the importance of early screening contributes to low cancer screening rates in the population. Aims: A collaborative initiative between David Omenukor Foundation and Fight Colorectal Cancer Organization strives to cancer awareness and screening in the population. Strategy: The David Omenukor Foundation organized a 5-km WALK-A-THON in Mesquite, Texas, on March 10, 2018, as part of the activities to observe the March Colorectal Cancer Awareness Month. During the event, participants received free screening for colorectal, breast, and prostate cancers. Free cholesterol, diabetes, and blood pressure testing were also done because of the impact of these comorbidities on health outcomes. Education experts on cancer were available to teach aspects of healthy diets and exercise. Two cancer patients and a survivor also shared their experiences. Program/Policy process: The program seeks to increase cancer awareness among populations and promote the culture of early and regular screening. Outcomes: Free colorectal and breast cancer screenings were provided to 270 people. About 60 people received free prostate-specific antigen (PSA) test, whereas 135 people received fecal occult blood testing. Similarly, 75 women received mammogram testing. The total number of patients who received colorectal cancer screening increased from 50 on 11th March 2017 to 135 on March 11th, 2018. Impact: The foundation created awareness of all forms of cancer and emphasized the value of early screening as the most effective to avoid the cancer scourge. The participants benefitted from nutritional advice as one strategy for reducing the risk of colorectal cancer. The event indicated that the campaign on early screening for detection was beginning to catch up. Regular interactive events and screenings increase knowledge of cancer and reduce disparities in cancer screening in the community.

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21

Chen, Jin-Lian, Jing Fan, Liu-Shui Yan, Hui-Qin Guo, Jing-Jing Xiong, Yan Ren, and Jun-Duo Hu. "Urine Metabolite Profiling of Human Colorectal Cancer by Capillary Electrophoresis Mass Spectrometry Based on MRB." Gastroenterology Research and Practice 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/125890.

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Aim. The study was to investigate the metabolic profile of urine metabolites and to elucidate their clinical significance in patients with colorectal cancer.Methods. Colorectal cancers from early stage and advanced stage were used in this study. Urine samples of colorectal cancer patients and healthy adults were collected and subjected to capillary electrophoresis mass spectrometry based on moving reaction boundary analysis. The metabolic data were analyzed by SPSS 17.0 to find urinary biomarkers for colorectal cancer.Results. The results indicated that the urine metabolic profiling of colorectal cancer patients had significant changes compared with the normal controls, and there were also differences between early stage and advanced colorectal cancer patients. Compared with the control group, the levels of isoleucine, valine, arginine, lactate acid and leucine increased(P<0.05), but those of histidine, methionine, serine, aspartic acid, citric acid, succinate, and malic acid decreased in urine samples from colorectal cancer(P<0.05). Furthermore, the levels of isoleucine and valine were lower in urine of patients with advanced colorectal cancer than those in early stage colorectal cancer(P<0.05).Conclusion. The technique of capillary electrophoresis mass spectrometry based on MRB could reveal the significant metabolic alterations during progression of colorectal cancer, and the method is feasible and may be useful for the early diagnosis of colorectal cancer.

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22

Hayes, Richard B. "Advances in Understanding Early-Onset Colorectal Cancer." Cancer Epidemiology, Biomarkers & Prevention 30, no. 10 (October 1, 2021): 1775–77. http://dx.doi.org/10.1158/1055-9965.epi-21-0844.

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Abstract Since the 1990s, the incidence of early-onset colorectal cancer (at <50 years of age) in the US has increased by more than 50%; similar increases have also been observed internationally. These increases are found particularly among individuals born during and after the 1960s, raising the possibility that the increased rates of early-onset colorectal cancer are attributable to changes in risk-factor patterns throughout successive generations. The reasons for these alarming epidemiologic patterns for early-onset colorectal cancer worldwide are only recently being investigated and major gaps in our knowledge remain. In the current issue of this journal, Arif and colleagues differentiated characteristics and outcomes of early-onset colorectal cancer in patients with the predisposing conditions of inflammatory bowel disease or hereditary genetic syndromes, compared with patients who have sporadic disease. Also, in this issue, Schumacher and colleagues investigated risk factors for early-onset colorectal adenocarcinoma in a nested case-control study among Kaiser Permanente Southern California (KPSC) health plan members. The research presented on characteristics and outcomes points to the importance of sporadic disease in the rise of early-onset colorectal cancer, while the research presented on risk factors points to the importance of obesity as a potential explanatory factor for this rise. See related articles by Arif et al., p. 1785 and by Schumacher et al., p. 1792

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23

Yang, Daniel X., Cary Philip Gross, and James B. Yu. "Changes in early- and late-stage colorectal cancer incidence during the era of screening: 1976-2009." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 1522. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.1522.

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1522 Background: Ideally, screening detects cancer at a more curable stage, and as a result decreases the incidence of subsequent diagnosis at a late stage. Whereas breast cancer screening is suggested to have led to a substantial increase in the number of early-stage cancers diagnosed in the United States with only marginal reductions in the number of late stage cancers, the impact of colorectal cancer screening on cancer incidence is unknown. Methods: Colorectal cancer incidence data spanning over three decades, 1976—2009, were collected from the Surveillance, Epidemiology, and End Result (SEER) database. Screening utilization data spanning 1986—2010 were collected from the National Health Survey (NHS) progress reports. We examined trends in the incidence of early-stage (in situ, local) and late-stage (regional, distant) colorectal cancer among adults 50 years or older. Results: Over the past three decades, the incidence of late-stage colorectal cancer decreased significantly, from 118 to 74 cases per 100,000 people—a 37% decrease. The incidence of early-stage colorectal cancer also decreased, from 77 to 67 cases per 100,000 people. There was also an associated increase in the utilization rates of screening colonoscopy. From 1987 to 2010—the years for which NHS data were available—the percentage of adults 50 and older who received screening colonoscopy rose from 27% to 63%. After adjusting for trends in cancer incidence in non-screened populations, we estimated that colorectal screening was associated with a reduction of approximately 550,000 cases of colorectal cancer over the past three decades in the United States. Using the most conservative assumption of constant cancer incidence during the past three decades, 235,000 cases of colorectal cancer were prevented. Conclusions: There has been a significant decline in both early and late stage colorectal cancer diagnoses, during a time of increasing rates of increased screening.

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24

Pan, Zhe, Junfeng Huang, Mingkai Huang, Zhiyuan Yao, Jiongqiang Huang, Jingsong Chen, and Rongchang Wang. "Risk factors for early-onset colorectal cancer in China." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): 10542. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.10542.

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10542 Background: The incidence of colorectal cancer among persons aged < 50 years (early-onset colorectal cancer, EOCRC) has increased since the early 1990s. However, the risk factors contributing to this trend remain largely unknown. Methods: We conducted a retrospective study of participants who were aged < 50 years and without a previous cancer history, using the China Kadoorie Biobank cohort study. We analyzed data related to demographics, lifestyle habits, family history, and comorbidities of EOCRC cases with participants without colorectal cancer in this age group (controls). Univariate and multivariate-adjusted cox regression models were used to estimate the associations with risk factors. Results: We identified 225 EOCRC cases and 88842 controls that include the final analyses. Of the 225 EOCRC patients, 105 (46.7%) were colon cancers and 120 (53.3%) were rectum cancers. EOCRC cases were older, have more intake of fish and eggs, have higher BMIs, diabetes, and family history of cancer compared with controls (P < 0.05). After adjustment for potential confounding factors, increasing age (HR 2.18, 95%CI 2.05-2.31), BMI (HR 1.06, 95%CI 1.01-1.11), family history of cancer (HR 1.41, 95%CI 1.00-1.98), and more intake of fish (HR 1.54, 95%CI 1.09-2.19) were significantly associated with a higher risk of EOCRC. In sensitivity analyses stratified by cancer site (colon and rectum), the results remained consistent. Conclusions: Based on the large Chinese cohort study, we found increasing age, higher BMI or obesity, family history of cancer, and more intake of fish were independent risk factors for EOCRC. Further studies are needed to identify factors that cause the increasing incidence of EOCRC in China and other countries, and explore the potential mechanism behind.[Table: see text]

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25

Chu, Edward. "Colorectal Cancer Screening and Early Detection." Clinical Colorectal Cancer 9, no. 2 (April 2010): 75–76. http://dx.doi.org/10.3816/ccc.2010.n.009.

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26

Maruyama, M. "Radiographic diagnosis of early colorectal cancer." Nippon Daicho Komonbyo Gakkai Zasshi 41, no. 7 (1988): 873–83. http://dx.doi.org/10.3862/jcoloproctology.41.873.

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27

Kudo, S., T. Nakajima, H. Kusaka, G. Iinuma, S. Hirota, A. Takagi, Y. Shibata, K. Miura, M. Himori, and Y. Imai. "Endoscopic Therapy for Early Colorectal Cancer." Nippon Daicho Komonbyo Gakkai Zasshi 46, no. 8 (1993): 1007–14. http://dx.doi.org/10.3862/jcoloproctology.46.1007.

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28

Muller, Charles, Ehizokha Ihionkhan, Elena M. Stoffel, and Sonia S. Kupfer. "Disparities in Early-Onset Colorectal Cancer." Cells 10, no. 5 (April 26, 2021): 1018. http://dx.doi.org/10.3390/cells10051018.

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The incidence and mortality of early-onset colorectal cancer (CRC) are increasing in the United States (US) and worldwide. In the US, there are notable disparities in early-onset CRC burden by race/ethnicity and geography. African Americans, Hispanic/Latinos, and populations residing in specific regions of the Southern U.S. are disproportionately affected with CRC diagnosed at younger ages, while less is known about disparities in other countries. Reasons for these disparities are likely multi-factorial and potentially implicate differences in health determinants including biology/genetics, diet/environment, individual health behaviors, and access to high-quality health services, as well as social and policy factors. This review summarizes current understanding of early-onset CRC disparities and identifies specific research areas that will inform evidence-based interventions at individual, practice, and policy levels to reduce the global burden of this disease.

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29

Oka, Shiro, and Shinji Tanaka. "Magnifying Endoscopy for Early Colorectal Cancer." Nippon Daicho Komonbyo Gakkai Zasshi 65, no. 10 (2012): 793–99. http://dx.doi.org/10.3862/jcoloproctology.65.793.

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30

Oya, Masatoshi, Shinichi Sameshima, Nobumi Tagaya, Emiko Takeshita, Yoshitake Sugamata, Shinichiro Koketsu, Takashi Okuyama, and Hidemaro Yoshiba. "Surgical Procedures for Early Colorectal Cancer." Nippon Daicho Komonbyo Gakkai Zasshi 65, no. 10 (2012): 821–26. http://dx.doi.org/10.3862/jcoloproctology.65.821.

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31

Berger, Franklin G. "SPECIAL FOCUS: Early-onset colorectal cancer." Colorectal Cancer 9, no. 3 (September 1, 2020): CRC36. http://dx.doi.org/10.2217/crc-2020-0030.

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32

Falt, Přemysl. "Endoscopic treatment of early colorectal cancer." Vnitřní lékařství 68, no. 6 (October 3, 2022): 355–62. http://dx.doi.org/10.36290/vnl.2022.075.

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White, Victoria, and Richard Miller. "Colorectal cancer: prevention and early diagnosis." Medicine 35, no. 6 (June 2007): 297–301. http://dx.doi.org/10.1016/j.mpmed.2007.03.001.

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Dennis, Robert, Samson Tou, and Richard Miller. "Colorectal cancer: prevention and early diagnosis." Medicine 39, no. 5 (May 2011): 243–49. http://dx.doi.org/10.1016/j.mpmed.2011.02.012.

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Bhat, Shivaram K., and James E. East. "Colorectal cancer: prevention and early diagnosis." Medicine 43, no. 6 (June 2015): 295–98. http://dx.doi.org/10.1016/j.mpmed.2015.03.009.

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Stockenhuber, Krista, and James E. East. "Colorectal cancer: prevention and early diagnosis." Medicine 47, no. 7 (July 2019): 395–99. http://dx.doi.org/10.1016/j.mpmed.2019.04.001.

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Kashida, Hiroshi, Shinichi Nishiuma, Hiroshi Tei, Naoya Kimoto, Toyokazu Fukunaga, Akihiko Okada, Masahiro Hirasa, Yasuyoshi Ibuki, and Akio Orino. "4492 Depressed type early colorectal cancer." Gastrointestinal Endoscopy 51, no. 4 (April 2000): AB149. http://dx.doi.org/10.1016/s0016-5107(00)14339-1.

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Matsui, Toshiyuki, Sumio Tsuda, Kenshi Yao, Akinori Iwashita, Toshihiro Sakurai, and Tsuneyoshi Yao. "Natural history of early colorectal cancer." Diseases of the Colon & Rectum 43, Sup 10 (October 2000): S18—S22. http://dx.doi.org/10.1007/bf02237221.

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Kikuchi, Ryuichi, Masahiro Takano, Koichi Takagi, Naoyuki Fujimoto, Ryoichi Nozaki, Tateshi Fujiyoshi, and Yuzo Uchida. "Management of early invasive colorectal cancer." Diseases of the Colon & Rectum 38, no. 12 (December 1995): 1286–95. http://dx.doi.org/10.1007/bf02049154.

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Park, Young Jin, Woo-Ho Kim, Sung Suk Paeng, and Jae-Gahb Park. "Histoclinical Analysis of Early Colorectal Cancer." World Journal of Surgery 24, no. 9 (September 2000): 1029–35. http://dx.doi.org/10.1007/s002680010143.

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Nivatvongs, Santhat. "Surgical Management of Early Colorectal Cancer." World Journal of Surgery 24, no. 9 (September 2000): 1052–55. http://dx.doi.org/10.1007/s002680010148.

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Matsui, Toshiyuki, Tsuneyoshi Yao, and Akinori Iwashita. "Natural History of Early Colorectal Cancer." World Journal of Surgery 24, no. 9 (September 2000): 1022–28. http://dx.doi.org/10.1007/s002680010153.

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ROZEN, P. "Colorectal cancer: does early detection matter?" Postgraduate Medical Journal 77, no. 907 (May 1, 2001): 289–91. http://dx.doi.org/10.1136/pmj.77.907.289.

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Takeuchi, Yoji, Noboru Hanaoka, Masao Hanafusa, Ryu Ishihara, Koji Higashino, Hiroyasu Iishi, and Noriya Uedo. "Autofluorescence imaging of early colorectal cancer." Journal of Biophotonics 4, no. 7-8 (May 9, 2011): 490–97. http://dx.doi.org/10.1002/jbio.201100013.

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Munakata, Y., and K. Hayashi. "Laparoscopic Bowel Surgery for Cancer. Laparoscopic Colorectal Surgery for Early Colorectal Cancer." Nippon Daicho Komonbyo Gakkai Zasshi 50, no. 10 (1997): 1132–37. http://dx.doi.org/10.3862/jcoloproctology.50.1132.

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Cao, Yin. "Abstract IA013: Early-onset colorectal cancer: Emerging risk factors and early detection." Cancer Research 82, no. 23_Supplement_1 (December 1, 2022): IA013. http://dx.doi.org/10.1158/1538-7445.crc22-ia013.

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Анотація:

Abstract Early-onset colorectal cancer (CRC) is increasing in the United States and globally. Compared to CRC diagnosed at older ages, patients with early-onset CRC experienced significant diagnostic delays, with tumors of advanced clinicopathological features and unknown etiology. While screening recommendations have been recently lowered to age 45 in the United States, about half of early-onset CRC cases are diagnosed before age 45, thus will not be detected via screening. This presentation will review emerging risk factors of early-onset CRC throughout the life course, as well as clinical signs and symptoms associated with early-onset CRC. Citation Format: Yin Cao. Early-onset colorectal cancer: Emerging risk factors and early detection [abstract]. In: Proceedings of the AACR Special Conference on Colorectal Cancer; 2022 Oct 1-4; Portland, OR. Philadelphia (PA): AACR; Cancer Res 2022;82(23 Suppl_1):Abstract nr IA013.

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Robertson, John M. "Early Diagnosis and Treatment of Cancer: Colorectal Cancer." International Journal of Radiation Oncology*Biology*Physics 79, no. 5 (April 2011): 1597. http://dx.doi.org/10.1016/j.ijrobp.2010.11.044.

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