Добірка наукової літератури з теми "Dopaminergic neurons - Transplantation"
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Статті в журналах з теми "Dopaminergic neurons - Transplantation"
Breeze, Robert E. "TRANSPLANTATION OF EMBRYONIC DOPAMINERGIC NEURONS." Neurosurgery 49, no. 3 (September 1, 2001): 575–76. http://dx.doi.org/10.1097/00006123-200109000-00006.
Повний текст джерелаBreeze, Robert E. "TRANSPLANTATION OF EMBRYONIC DOPAMINERGIC NEURONS." Neurosurgery 49, no. 3 (September 2001): 575–76. http://dx.doi.org/10.1227/00006123-200109000-00006.
Повний текст джерелаLindvall, Olle. "Treatment of Parkinson's disease using cell transplantation." Philosophical Transactions of the Royal Society B: Biological Sciences 370, no. 1680 (October 19, 2015): 20140370. http://dx.doi.org/10.1098/rstb.2014.0370.
Повний текст джерелаXiao, Jia-Jia, Ming Yin, Ze-Jian Wang, and Xiao-Ping Wang. "Transplanted Neural Stem Cells: Playing a Neuroprotective Role by Ceruloplasmin in the Substantia Nigra of PD Model Rats?" Oxidative Medicine and Cellular Longevity 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/618631.
Повний текст джерелаLi, Wen, Elisabet Englund, Håkan Widner, Bengt Mattsson, Danielle van Westen, Jimmy Lätt, Stig Rehncrona, et al. "Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain." Proceedings of the National Academy of Sciences 113, no. 23 (May 2, 2016): 6544–49. http://dx.doi.org/10.1073/pnas.1605245113.
Повний текст джерелаPetersén, Åsa, Oskar Hansson, Mia Emgård, and Patrik Brundin. "Grafting of Nigral Tissue Hibernated with Tirilazad Mesylate and Glial Cell Line-Derived Neurotrophic Factor." Cell Transplantation 9, no. 5 (September 2000): 577–84. http://dx.doi.org/10.1177/096368970000900503.
Повний текст джерелаSawamoto, K., N. Nakao, K. Kobayashi, N. Matsushita, H. Takahashi, K. Kakishita, A. Yamamoto, et al. "Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons." Proceedings of the National Academy of Sciences 98, no. 11 (May 15, 2001): 6423–28. http://dx.doi.org/10.1073/pnas.111152398.
Повний текст джерелаVukicevic, Vladimir, Janine Schmid, Andreas Hermann, Sven Lange, Nan Qin, Linda Gebauer, Kuei-Fang Chung, et al. "Differentiation of Chromaffin Progenitor Cells to Dopaminergic Neurons." Cell Transplantation 21, no. 11 (November 2012): 2471–86. http://dx.doi.org/10.3727/096368912x638874.
Повний текст джерелаPark, Hyunjun, and Keun-A. Chang. "Therapeutic Potential of Repeated Intravenous Transplantation of Human Adipose-Derived Stem Cells in Subchronic MPTP-Induced Parkinson’s Disease Mouse Model." International Journal of Molecular Sciences 21, no. 21 (October 30, 2020): 8129. http://dx.doi.org/10.3390/ijms21218129.
Повний текст джерелаEmgard-Mattson, Mia, Jenny Karlsson, Naoyuki Nakao, and Patrik Brundin. "Addition of Lateral Ganglionic Eminence to Rat Mesencephalic Grafts Affects Fiber Outgrowth but Does not Enhance Function." Cell Transplantation 6, no. 3 (May 1997): 277–86. http://dx.doi.org/10.1177/096368979700600310.
Повний текст джерелаДисертації з теми "Dopaminergic neurons - Transplantation"
Zietlow, Rike. "Factors affecting the survival of embryonic dopaminergic neurones after transplantation." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624313.
Повний текст джерелаLove, Rebecca Margaret. "Improving the survival of embryonic dopaminergic neurons." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343277.
Повний текст джерелаDaniel, James St Vincent Clinical School UNSW. "Studies of neurotransmitter release mechanisms in dopamine neurons." Awarded by:University of New South Wales. St. Vincent Clinical School, 2007. http://handle.unsw.edu.au/1959.4/31934.
Повний текст джерелаSamata, Bumpei. "Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1." 京都大学 (Kyoto University), 2017. http://hdl.handle.net/2433/225509.
Повний текст джерелаScholz, Torben [Verfasser], and Guido [Akademischer Betreuer] Nikkhah. "Development of dopaminergic neurons from neural stem cells and transplantation into a neonatal and adult animal model of Parkinson’s disease = Entwicklung dopaminerger Neurone aus neuralen Stammzellen und Transplantation in ein neonatales und adultes Modell der Parkinsonschen Krankheit." Freiburg : Universität, 2011. http://d-nb.info/112346460X/34.
Повний текст джерелаTorikoshi, Sadaharu. "Exercise Promotes Neurite Extensions from Grafted Dopaminergic Neurons in the Direction of the Dorsolateral Striatum in Parkinson’s Disease Model Rats." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263556.
Повний текст джерелаBrisson, Sandie. "Potentiel thérapeutique de neurones dopaminergiques dérivés de cellules souches embryonnaires de souris dans un modèle murin de la maladie de Parkinson." Thesis, Poitiers, 2017. http://www.theses.fr/2017POIT2314.
Повний текст джерелаParkinson’s disease (PD) is mainly characterised by the progressive loss of the dopaminergic (DA) neurons of the subtantia nigra pars compacta (SNpc) that are innervating the striatum and controlling voluntary movements. One of the therapeutical strategies of PD is the ectopic transplant of fetal DA precursors from the ventral mesencephalon (VM) into the striatum. It is unlikely that transplant of human DA neurons of the VM become a routine treatment for PD due to supply and tissues standardization problems for the transplant. The future of these transplants thus depends on the obtaining of alternative tissue sources. The aim of this project is to obtain DA neurons derived from mouse embryonic stem cells and to evaluate their therapeutical potential grafting them into the striatum or the SNpc in a mouse model of PD. In order to increase the number of DA neurons of the nigral subtype, the expression of LMX1A, a transcription factor playing a key role in the embryonic development of MV DA neuronal progenitors, was forced. We have shown that, in vitro, LMX1A induces an increase of nigral precursors and neurons. After transplantation into the SN or the striatum, the cells survive, express markers of DA neurons of the nigral subtype and project towards the striatum. The forced expression of LMX1A seems to increase, in vivo, the proportion of mature DA neurons responsible for reducing the motor deficits after transplantation into the striatum
Thinyane, Keneuoe Hycianth. "Transplantation of mouse embryonic stem cell-derived dopaminergic neurons in a unilateral 6-hydroxydopamine lesion rat model of Parkinson's disease characterisation of the fate of the engrafted cells and the host responses /." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=975112600.
Повний текст джерелаDong, Jing-fei. "Morphological and biochemical characterization of human second trimester foetal dopaminergic neurones and identification of factors influencing their survival and preservation in vitro : a study related to clinical neural transplantation for Parkinson's d." Thesis, University of Wolverhampton, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357198.
Повний текст джерелаCheng, Yun-Chih, and 鄭遠芝. "Transplantation of dopaminergic neurons derived from human umbilical mesenchymal stem cells into striatum of hemiparkinsonian rats." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/06771948236164021847.
Повний текст джерела國立陽明大學
解剖暨細胞生物學研究所
92
Transplantation of stem cells has been the foresight to rescue human neurodegenerative diseases in recent years. Embryonic stem cells are pluripotent. Transplantation of embryonic or fetus tissue is hindered by disputations in the aspects of religion, law and ethic, and therefore not available to all. Bone marrow has come into notice. Bone marrow contains heamatopoietic stem cells that provide a continuous source for progenitors of red blood cells, white blood cells and platelets. Moreover, bone marrow also contains nonheamatopoietic stem cells that have been referred to as bone marrow stromal cells or bone marrow mesenchymal stem cells. Bone marrow stromal cells are capable of differentiating into osteogenic, chondrogenic and neurogenic lineages in vitro. However, the number of bone marrow stromal cells significantly decreases with age (Rao and Mattson, 2001). Therefore, it is more urgent to find an alternative source of stem cells. Direct transplantation of stem cells, a relatively low percentage of cells differentiates into neurons with the majority into glia and thus cannot rescue the neurological disease (Azizi et al., 1998 ;McDonald et al.,1999). Therefore, transplantation of postmitosis neurons derived from stem cells has become an effective and direct treatment for the neurological diseases. We have shown a novel source of stem cells from Wharton’s jelly of human umbilical cord. The human umbilical mesenchymal stem cells (HUMSCs) were cultured and differentiated into dopaminergic neurons in vitro, and then transplanted into striatum of hemiparkinsonian rats. Here we showed quantities of HUMSCs that extrated from Wharton’s jelly of human umbilical cord. At the sixth-ninth day of cultured in neuronal condition medium (NCM), the percentage of HUMSCs expressed neurofilament could as high as 87%, and less than 5% of HUMSCs differentiated into astrocytes and microglia. Transplantation of neurons derived from HUMSCs into striatum of hemiparkinsonian rats, the cells survived in striatum after 4 months. However, the rotation behavior of hemiparkinsonian rats was still not improved. Differentiation of HUMSCs into dopaminergic neurons is necessary for success in behavioral recovery of hemiparkinsonian rats. HUMSCs were cultured in NCM for 6 days, and then Shh and FGF8 were added. 12.7% of HUMSCs differentiated into dopaminergic neurons after Shh and FGF8 treatment. The rotation behavior become alleviated, but could not back to normal after transplantation of dopaminergic neurons derived from HUMSCs into striatum of hemiparkinsonian rats. Our results suggest that HUMSCs have great potentialities for differentiation into dopaminergic neurons after Shh and FGF8 treatment. However, the low proportion of dopaminergic neurons generation may not be sufficient to recover from Parkinson’s disease. Now we are excusing a plan to transfect Nurr1 gene into human umbilical mesenchymal stem cells to generate dopaminergic neurons in quantity to rescue Parkinson’s disease efficiently.
Книги з теми "Dopaminergic neurons - Transplantation"
Triarhou, Lazaros C. Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson’s Disease. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0699-7.
Повний текст джерелаDong, Jing-fei. Morphological and biochemical characterization of human second trimester foetal dopaminergic neurones and identification of factors influencing their survival and preservation in vitro: A study related to clinical neural transplantation for Parkinson's disease. Wolverhampton: University of Wolverhampton, 1993.
Знайти повний текст джерелаTriarhou, Lazaros C. Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson's Disease. Springer, 2012.
Знайти повний текст джерелаDopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson's Disease. Springer, 2003.
Знайти повний текст джерелаTriarhou, Lazaros C. Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson's Disease (Advances in Experimental Medicine and Biology, 517). Kluwer Academic/Plenum Publishers, 2002.
Знайти повний текст джерелаЧастини книг з теми "Dopaminergic neurons - Transplantation"
Takahashi, Jun, Yasushi Takagi, and Hidemoto Saiki. "Transplantation of Embryonic Stem Cell-Derived Dopaminergic Neurons in MPTP-Treated Monkeys." In Methods in Molecular Biology, 199–212. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-060-7_13.
Повний текст джерелаSeiger, Ake, Lars Olson, Ingrid Stromberg, Marc Bygdeman, Menek Goldstein, and Barry Hoffer. "Transplantation of Human Dopaminergic Neurons in Parkinsonism: Experimental Reality and Future Clinical Feasibility." In Progress in Parkinson Research, 219–23. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0759-4_28.
Повний текст джерелаTriarhou, Lazaros C. "Introduction." In Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson’s Disease, 1–14. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0699-7_1.
Повний текст джерелаTriarhou, Lazaros C. "Biology and Pathology of the Weaver Mutant Mouse." In Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson’s Disease, 15–42. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0699-7_2.
Повний текст джерелаTriarhou, Lazaros C. "Histochemical Properties of Intrastriatal Mesencephalic Grafts." In Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson’s Disease, 43–61. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0699-7_3.
Повний текст джерелаTriarhou, Lazaros C. "Structural Correlates of Process Outgrowth and Circuit Reconstruction." In Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson’s Disease, 63–88. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0699-7_4.
Повний текст джерелаTriarhou, Lazaros C. "Neurochemical Indices of Functional Restoration." In Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson’s Disease, 89–105. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0699-7_5.
Повний текст джерелаTriarhou, Lazaros C. "Behavioral Recovery of Functional Responses." In Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson’s Disease, 107–25. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0699-7_6.
Повний текст джерелаTriarhou, Lazaros C. "Directions for Future Research." In Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson’s Disease, 127–42. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0699-7_7.
Повний текст джерелаChung, Sangmi, Jisook Moon, and Kwang-Soo Kim. "Improvement of Neurological Dysfunctions in Aphakia Mice, a Model of Parkinson’s Disease, after Transplantation of ES Cell-Derived Dopaminergic Neuronal Precursors." In Methods in Molecular Biology, 285–91. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1453-1_23.
Повний текст джерела