Щоб переглянути інші типи публікацій з цієї теми, перейдіть за посиланням: DNA nanoarrays.

Статті в журналах з теми "DNA nanoarrays"

Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями

Оберіть тип джерела:

Ознайомтеся з топ-50 статей у журналах для дослідження на тему "DNA nanoarrays".

Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.

Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.

Переглядайте статті в журналах для різних дисциплін та оформлюйте правильно вашу бібліографію.

1

Yang, Yang, and Chenxiang Lin. "Directing reconfigurable DNA nanoarrays." Science 357, no. 6349 (July 27, 2017): 352–53. http://dx.doi.org/10.1126/science.aao0599.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
2

Hao, X., E. A. Josephs, Q. Gu, and T. Ye. "Molecular conformations of DNA targets captured by model nanoarrays." Nanoscale 9, no. 36 (2017): 13419–24. http://dx.doi.org/10.1039/c7nr04715k.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
3

NAKAO, Hidenobu, Futoshi IWATA, Hidenori KARASAWA, Hideki HAYASHI, and Kazushi MIKI. "Fabrication of Metallic Nanoarrays using DNA Templates." Hyomen Kagaku 28, no. 7 (2007): 372–77. http://dx.doi.org/10.1380/jsssj.28.372.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
4

Hawkes, William, Da Huang, Paul Reynolds, Linda Hammond, Matthew Ward, Nikolaj Gadegaard, John F. Marshall, Thomas Iskratsch, and Matteo Palma. "Probing the nanoscale organisation and multivalency of cell surface receptors: DNA origami nanoarrays for cellular studies with single-molecule control." Faraday Discussions 219 (2019): 203–19. http://dx.doi.org/10.1039/c9fd00023b.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
5

Piccone, Ashley. "DNA origami folds proteins into nanoarrays with precision." Scilight 2022, no. 34 (August 19, 2022): 341107. http://dx.doi.org/10.1063/10.0013751.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
6

Liu, Yan, Yonggang Ke, and Hao Yan. "Self-Assembly of Symmetric Finite-Size DNA Nanoarrays." Journal of the American Chemical Society 127, no. 49 (December 2005): 17140–41. http://dx.doi.org/10.1021/ja055614o.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
7

Mei, Qian, Xixi Wei, Fengyu Su, Yan Liu, Cody Youngbull, Roger Johnson, Stuart Lindsay, Hao Yan, and Deirdre Meldrum. "Stability of DNA Origami Nanoarrays in Cell Lysate." Nano Letters 11, no. 4 (April 13, 2011): 1477–82. http://dx.doi.org/10.1021/nl1040836.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
8

Ghosh, Sumana, and Eric Defrancq. "Metal-Complex/DNA Conjugates: A Versatile Building Block for DNA Nanoarrays." Chemistry - A European Journal 16, no. 43 (October 4, 2010): 12780–87. http://dx.doi.org/10.1002/chem.201001590.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
9

Cervantes-Salguero, K., M. Freeley, R. E. A. Gwyther, D. D. Jones, J. L. Chávez, and M. Palma. "Single molecule DNA origami nanoarrays with controlled protein orientation." Biophysics Reviews 3, no. 3 (September 2022): 031401. http://dx.doi.org/10.1063/5.0099294.

Повний текст джерела
Анотація:
The nanoscale organization of functional (bio)molecules on solid substrates with nanoscale spatial resolution and single-molecule control—in both position and orientation—is of great interest for the development of next-generation (bio)molecular devices and assays. Herein, we report the fabrication of nanoarrays of individual proteins (and dyes) via the selective organization of DNA origami on nanopatterned surfaces and with controlled protein orientation. Nanoapertures in metal-coated glass substrates were patterned using focused ion beam lithography; 88% of the nanoapertures allowed immobilization of functionalized DNA origami structures. Photobleaching experiments of dye-functionalized DNA nanostructures indicated that 85% of the nanoapertures contain a single origami unit, with only 3% exhibiting double occupancy. Using a reprogrammed genetic code to engineer into a protein new chemistry to allow residue-specific linkage to an addressable ssDNA unit, we assembled orientation-controlled proteins functionalized to DNA origami structures; these were then organized in the arrays and exhibited single molecule traces. This strategy is of general applicability for the investigation of biomolecular events with single-molecule resolution in defined nanoarrays configurations and with orientational control of the (bio)molecule of interest.
Стилі APA, Harvard, Vancouver, ISO та ін.
10

Sathish, Shivani, Sébastien G. Ricoult, Kazumi Toda-Peters, and Amy Q. Shen. "Microcontact printing with aminosilanes: creating biomolecule micro- and nanoarrays for multiplexed microfluidic bioassays." Analyst 142, no. 10 (2017): 1772–81. http://dx.doi.org/10.1039/c7an00273d.

Повний текст джерела
Анотація:
Aqueous based microcontact printing (μCP) to create micro- and nanoarrays of (3-aminopropyl)triethoxysilane (APTES) on glass substrates of microfluidic devices for covalent immobilization of DNA aptamers and antibodies.
Стилі APA, Harvard, Vancouver, ISO та ін.
11

Burns, Jonathan R., Jurgita Zekonyte, Giuliano Siligardi, Rohanah Hussain, and Eugen Stulz. "Directed Formation of DNA Nanoarrays through Orthogonal Self-Assembly." Molecules 16, no. 6 (June 15, 2011): 4912–22. http://dx.doi.org/10.3390/molecules16064912.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
12

Noh, Hyunwoo, Albert M. Hung, Chulmin Choi, Ju Hun Lee, Jin-Yeol Kim, Sungho Jin, and Jennifer N. Cha. "50 nm DNA Nanoarrays Generated from Uniform Oligonucleotide Films." ACS Nano 3, no. 8 (July 14, 2009): 2376–82. http://dx.doi.org/10.1021/nn900559m.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
13

Tam, Jenny M., Linan Song, and David R. Walt. "DNA detection on ultrahigh-density optical fiber-based nanoarrays." Biosensors and Bioelectronics 24, no. 8 (April 2009): 2488–93. http://dx.doi.org/10.1016/j.bios.2008.12.034.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
14

Ghosh, Sumana, and Eric Defrancq. "ChemInform Abstract: Metal-Complex/DNA Conjugates: A Versatile Building Block for DNA Nanoarrays." ChemInform 42, no. 11 (February 17, 2011): no. http://dx.doi.org/10.1002/chin.201111265.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
15

Akbulut, Ozge, Jin-Mi Jung, Ryan D. Bennett, Ying Hu, Hee-Tae Jung, Robert E. Cohen, Anne M. Mayes, and Francesco Stellacci. "Application of Supramolecular Nanostamping to the Replication of DNA Nanoarrays." Nano Letters 7, no. 11 (November 2007): 3493–98. http://dx.doi.org/10.1021/nl0720758.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
16

Chhabra, Rahul, Jaswinder Sharma, Yonggang Ke, Yan Liu, Sherri Rinker, Stuart Lindsay, and Hao Yan. "Spatially Addressable Multiprotein Nanoarrays Templated by Aptamer-Tagged DNA Nanoarchitectures." Journal of the American Chemical Society 129, no. 34 (August 2007): 10304–5. http://dx.doi.org/10.1021/ja072410u.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
17

NAKAO, Hidenobu, Hideki HAYASHI, Hiroshi SHIIGI, and Kazushi MIKI. "Highly Localized Light Field on Metallic Nanoarrays Prepared with DNA Nanofibers." Analytical Sciences 25, no. 10 (2009): 1177–79. http://dx.doi.org/10.2116/analsci.25.1177.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
18

Shetty, Rishabh M., Sarah R. Brady, Paul W. K. Rothemund, Rizal F. Hariadi, and Ashwin Gopinath. "Bench-Top Fabrication of Single-Molecule Nanoarrays by DNA Origami Placement." ACS Nano 15, no. 7 (July 6, 2021): 11441–50. http://dx.doi.org/10.1021/acsnano.1c01150.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
19

Zhang, Guo-Jun. "A novel approach to Au nanoparticle-based identification of DNA nanoarrays." Frontiers in Bioscience 12, no. 8-12 (2007): 4773. http://dx.doi.org/10.2741/2425.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
20

Gopinath, Ashwin, and Paul W. K. Rothemund. "Optimized Assembly and Covalent Coupling of Single-Molecule DNA Origami Nanoarrays." ACS Nano 8, no. 12 (December 9, 2014): 12030–40. http://dx.doi.org/10.1021/nn506014s.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
21

Bano, Fouzia, Ljiljana Fruk, Barbara Sanavio, Maximilian Glettenberg, Loredana Casalis, Christof M. Niemeyer, and Giacinto Scoles. "Toward Multiprotein Nanoarrays Using Nanografting and DNA Directed Immobilization of Proteins." Nano Letters 9, no. 7 (July 8, 2009): 2614–18. http://dx.doi.org/10.1021/nl9008869.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
22

Drmanac, R., A. B. Sparks, M. J. Callow, A. L. Halpern, N. L. Burns, B. G. Kermani, P. Carnevali, et al. "Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays." Science 327, no. 5961 (November 5, 2009): 78–81. http://dx.doi.org/10.1126/science.1181498.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
23

Kannegulla, Akash, Ye Liu, Bo Wu, and Li-Jing Cheng. "Plasmonic Open-Ring Nanoarrays for Broadband Fluorescence Enhancement and Ultrasensitive DNA Detection." Journal of Physical Chemistry C 122, no. 1 (December 19, 2017): 770–76. http://dx.doi.org/10.1021/acs.jpcc.7b09769.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
24

Mei, Qian, Roger H. Johnson, Xixi Wei, Fengyu Su, Yan Liu, Laimonas Kelbauskas, Stuart Lindsay, Deirdre R. Meldrum, and Hao Yan. "On-chip isotachophoresis separation of functional DNA origami capture nanoarrays from cell lysate." Nano Research 6, no. 10 (July 27, 2013): 712–19. http://dx.doi.org/10.1007/s12274-013-0347-1.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
25

Ghosh, Sumana, Isabelle Pignot-Paintrand, Pascal Dumy, and Eric Defrancq. "Design and synthesis of novel hybrid metal complex–DNA conjugates: key building blocks for multimetallic linear DNA nanoarrays." Organic & Biomolecular Chemistry 7, no. 13 (2009): 2729. http://dx.doi.org/10.1039/b904758a.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
26

Numajiri, Kentaro, Takahiro Yamazaki, Mayumi Kimura, Akinori Kuzuya, and Makoto Komiyama. "Discrete and Active Enzyme Nanoarrays on DNA Origami Scaffolds Purified by Affinity Tag Separation." Journal of the American Chemical Society 132, no. 29 (July 28, 2010): 9937–39. http://dx.doi.org/10.1021/ja104702q.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
27

Choi, Youngeun, Lisa Kotthoff, Lydia Olejko, Ute Resch-Genger, and Ilko Bald. "DNA Origami-Based Förster Resonance Energy-Transfer Nanoarrays and Their Application as Ratiometric Sensors." ACS Applied Materials & Interfaces 10, no. 27 (June 19, 2018): 23295–302. http://dx.doi.org/10.1021/acsami.8b03585.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
28

Zhang, Zhiqing, Jie Ma, Guodong Zhang, Xiaoyan Ding, Ruyan Zhang, Ting Zhou, Xiufeng Wang, and Fang Wang. "Large-Scale DNA Nanoarrays with a Controllable Fluorescence Switch Constructed by RCA Simplified Origami." Langmuir 36, no. 37 (August 25, 2020): 10989–95. http://dx.doi.org/10.1021/acs.langmuir.0c01821.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
29

Zeng, Yong, Mei He, and D. Jed Harrison. "Microfluidic Self-Patterning of Large-Scale Crystalline Nanoarrays for High-Throughput Continuous DNA Fractionation." Angewandte Chemie 120, no. 34 (August 11, 2008): 6488–91. http://dx.doi.org/10.1002/ange.200800816.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
30

Zeng, Yong, Mei He, and D. Jed Harrison. "Microfluidic Self-Patterning of Large-Scale Crystalline Nanoarrays for High-Throughput Continuous DNA Fractionation." Angewandte Chemie International Edition 47, no. 34 (August 11, 2008): 6388–91. http://dx.doi.org/10.1002/anie.200800816.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
31

Hager, Roland, Jonathan R. Burns, Martyna J. Grydlik, Alma Halilovic, Thomas Haselgrübler, Friedrich Schäffler, and Stefan Howorka. "Co-Immobilization of Proteins and DNA Origami Nanoplates to Produce High-Contrast Biomolecular Nanoarrays." Small 12, no. 21 (April 9, 2016): 2877–84. http://dx.doi.org/10.1002/smll.201600311.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
32

Zhou, Chensheng, Heng Luo, Xiaolu Feng, Xingwang Li, Jie Zhu, Lin He, and Can Li. "FOLDNA, a Web Server for Self-Assembled DNA Nanostructure Autoscaffolds and Autostaples." Journal of Nanotechnology 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/453953.

Повний текст джерела
Анотація:
DNA self-assembly is a nanotechnology that folds DNA into desired shapes. Self-assembled DNA nanostructures, also known as origami, are increasingly valuable in nanomaterial and biosensing applications. Two ways to use DNA nanostructures in medicine are to form nanoarrays, and to work as vehicles in drug delivery. The DNA nanostructures perform well as a biomaterial in these areas because they have spatially addressable and size controllable properties. However, manually designing complementary DNA sequences for self-assembly is a technically demanding and time consuming task, which makes it advantageous for computers to do this job instead. We have developed a web server, FOLDNA, which can automatically design 2D self-assembled DNA nanostructures according to custom pictures and scaffold sequences provided by the users. It is the first web server to provide an entirely automatic design of self-assembled DNA nanostructure, and it takes merely a second to generate comprehensive information for molecular experiments including: scaffold DNA pathways, staple DNA directions, and staple DNA sequences. This program could save as much as several hours in the designing step for each DNA nanostructure. We randomly selected some shapes and corresponding outputs from our server and validated its performance in molecular experiments.
Стилі APA, Harvard, Vancouver, ISO та ін.
33

Hu, Xiu Lan, Yoshitake Masuda, Tatsuki Ohji, and Kazumi Kato. "ZnO Nanoarrays Film Grown by Forced-Hydrolysis-Initiated-Nucleation Technique and its Photo-Induced Electrical Property." Key Engineering Materials 421-422 (December 2009): 83–86. http://dx.doi.org/10.4028/www.scientific.net/kem.421-422.83.

Повний текст джерела
Анотація:
Anhydrous zinc acetate pre-coated on the FTO substrate was served as a template layer, and ZnO nanowhisker arrays were simply and successfully fabricated by its forced-hydrolysis-initiated-nucleation of the layer in an aqueous solution at low temperature below 100 °C. The technique doesn’t need any expensive metal catalyst and high-temperature treatment. The density, diameter and length of whiskers were controllable by changing the deposition time. As-grown ZnO nanoarrays showed photo-induced electrical property. Enhanced photo-induced current (2.0~3.0  10-5 A) was detected under laser irradiation after DNA molecules labeled with dye molecules were loaded on the ZnO nanowhisker arrays.
Стилі APA, Harvard, Vancouver, ISO та ін.
34

Kim, Shin Ae, Kyung Min Byun, Kyujung Kim, Sung Min Jang, Kyungjae Ma, Youngjin Oh, Donghyun Kim, Sung Guk Kim, Michael L. Shuler, and Sung June Kim. "Surface-enhanced localized surface plasmon resonance biosensing of avian influenza DNA hybridization using subwavelength metallic nanoarrays." Nanotechnology 21, no. 35 (August 9, 2010): 355503. http://dx.doi.org/10.1088/0957-4484/21/35/355503.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
35

Kim, Shin Ae, Kyung Min Byun, Kyujung Kim, Sung Min Jang, Kyungjae Ma, Youngjin Oh, Donghyun Kim, Sung Guk Kim, Michael L. Shuler, and Sung June Kim. "Surface-enhanced localized surface plasmon resonance biosensing of avian influenza DNA hybridization using subwavelength metallic nanoarrays." Nanotechnology 22, no. 28 (June 6, 2011): 289501. http://dx.doi.org/10.1088/0957-4484/22/28/289501.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
36

Kielar, Charlotte, Francesco V. Reddavide, Stefan Tubbenhauer, Meiying Cui, Xiaodan Xu, Guido Grundmeier, Yixin Zhang, and Adrian Keller. "Pharmacophore Nanoarrays on DNA Origami Substrates as a Single-Molecule Assay for Fragment-Based Drug Discovery." Angewandte Chemie 130, no. 45 (October 9, 2018): 15089–93. http://dx.doi.org/10.1002/ange.201806778.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
37

Bae, Dong Geun, Ji-Eun Jeong, Seok Hee Kang, Myunghwan Byun, Dong-Wook Han, Zhiqun Lin, Han Young Woo, and Suck Won Hong. "A Nonconventional Approach to Patterned Nanoarrays of DNA Strands for Template-Assisted Assembly of Polyfluorene Nanowires." Small 12, no. 31 (June 28, 2016): 4254–63. http://dx.doi.org/10.1002/smll.201601346.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
38

Kielar, Charlotte, Francesco V. Reddavide, Stefan Tubbenhauer, Meiying Cui, Xiaodan Xu, Guido Grundmeier, Yixin Zhang, and Adrian Keller. "Pharmacophore Nanoarrays on DNA Origami Substrates as a Single-Molecule Assay for Fragment-Based Drug Discovery." Angewandte Chemie International Edition 57, no. 45 (October 9, 2018): 14873–77. http://dx.doi.org/10.1002/anie.201806778.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
39

Chen, Wen, and Gary B. Schuster. "DNA-Programmed Modular Assembly of Cyclic and Linear Nanoarrays for the Synthesis of Two-Dimensional Conducting Polymers." Journal of the American Chemical Society 134, no. 2 (December 21, 2011): 840–43. http://dx.doi.org/10.1021/ja210007f.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
40

Huang, Da, Ketan Patel, Sandra Perez-Garrido, John F. Marshall, and Matteo Palma. "DNA Origami Nanoarrays for Multivalent Investigations of Cancer Cell Spreading with Nanoscale Spatial Resolution and Single-Molecule Control." ACS Nano 13, no. 1 (December 27, 2018): 728–36. http://dx.doi.org/10.1021/acsnano.8b08010.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
41

Kuzuya, Akinori, Mayumi Kimura, Kentaro Numajiri, Naohiro Koshi, Toshiyuki Ohnishi, Fuminori Okada, and Makoto Komiyama. "Precisely Programmed and Robust 2D Streptavidin Nanoarrays by Using Periodical Nanometer-Scale Wells Embedded in DNA Origami Assembly." ChemBioChem 10, no. 11 (June 27, 2009): 1811–15. http://dx.doi.org/10.1002/cbic.200900229.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
42

Bae, Dong Geun, Ji-Eun Jeong, Seok Hee Kang, Myunghwan Byun, Dong-Wook Han, Zhiqun Lin, Han Young Woo, and Suck Won Hong. "Nanowires: A Nonconventional Approach to Patterned Nanoarrays of DNA Strands for Template-Assisted Assembly of Polyfluorene Nanowires (Small 31/2016)." Small 12, no. 31 (August 2016): 4160. http://dx.doi.org/10.1002/smll.201670154.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
43

Sinensky, Asher K., and Angela M. Belcher. "Label-free and high-resolution protein/DNA nanoarray analysis using Kelvin probe force microscopy." Nature Nanotechnology 2, no. 10 (September 23, 2007): 653–59. http://dx.doi.org/10.1038/nnano.2007.293.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
44

Li, Ming, Scott K. Cushing, Hongyan Liang, Savan Suri, Dongling Ma, and Nianqiang Wu. "Plasmonic Nanorice Antenna on Triangle Nanoarray for Surface-Enhanced Raman Scattering Detection of Hepatitis B Virus DNA." Analytical Chemistry 85, no. 4 (January 30, 2013): 2072–78. http://dx.doi.org/10.1021/ac303387a.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
45

Mao, Qing, Robert Chin, Weiwei Xie, Yuqing Deng, Wenwei Zhang, Huixin Xu, Rebecca Y. u. Zhang, et al. "Advanced Whole-Genome Sequencing and Analysis of Fetal Genomes from Amniotic Fluid." Clinical Chemistry 64, no. 4 (April 1, 2018): 715–25. http://dx.doi.org/10.1373/clinchem.2017.281220.

Повний текст джерела
Анотація:
Abstract BACKGROUND Amniocentesis is a common procedure, the primary purpose of which is to collect cells from the fetus to allow testing for abnormal chromosomes, altered chromosomal copy number, or a small number of genes that have small single- to multibase defects. Here we demonstrate the feasibility of generating an accurate whole-genome sequence of a fetus from either the cellular or cell-free DNA (cfDNA) of an amniotic sample. METHODS cfDNA and DNA isolated from the cell pellet of 31 amniocenteses were sequenced to approximately 50× genome coverage by use of the Complete Genomics nanoarray platform. In a subset of the samples, long fragment read libraries were generated from DNA isolated from cells and sequenced to approximately 100× genome coverage. RESULTS Concordance of variant calls between the 2 DNA sources and with parental libraries was >96%. Two fetal genomes were found to harbor potentially detrimental variants in chromodomain helicase DNA binding protein 8 (CHD8) and LDL receptor-related protein 1 (LRP1), variations of which have been associated with autism spectrum disorder and keratosis pilaris atrophicans, respectively. We also discovered drug sensitivities and carrier information of fetuses for a variety of diseases. CONCLUSIONS We were able to elucidate the complete genome sequence of 31 fetuses from amniotic fluid and demonstrate that the cfDNA or DNA from the cell pellet can be analyzed with little difference in quality. We believe that current technologies could analyze this material in a highly accurate and complete manner and that analyses like these should be considered for addition to current amniocentesis procedures.
Стилі APA, Harvard, Vancouver, ISO та ін.
46

Wei, Shih-Chung, Chia-Chen Chang, Tsung-Liang Chuang, Kung-Bin Sung, and Chii-Wann Lin. "Rapid Detection of Virus Nucleic Acid via Isothermal Amplification on Plasmonic Enhanced Digitizing Biosensor." Biosensors 12, no. 2 (January 28, 2022): 75. http://dx.doi.org/10.3390/bios12020075.

Повний текст джерела
Анотація:
Rapid detection for infectious diseases is highly demanded in diagnosis and infection prevention. In this work, we introduced a plasmonic enhanced digitizing biosensor for the rapid detection of nucleic acids. The sensor successfully achieved the detection of loop-mediated isothermal amplification for the hepatitis virus in this work. The sensor comprised a nanodisc array and Bst polymerases conjugated on the rough surface of a nanodisc. The rough surface of the nanodisc provided plasmonic hot spots to enhance the fluorescence signal. The virus DNA was detected by conducting a modified loop-mediated isothermal amplification with fluorescence resonance energy transfer reporter conjugated primers on the sensor. The modified isothermal amplification improved the signal contrast and detection time compared to the original assay. By integrating the modified amplification assay and plasmonic enhancement sensor, we achieved rapid detection of the hepatitis virus. Nucleic acid with a concentration of 10−3 to 10−4 mg/mL was detected within a few minutes by our design. Our digitizing plasmonic nanoarray biosensor also showed 20–30 min earlier detection compared to conventional loop-mediated isothermal amplification sensors.
Стилі APA, Harvard, Vancouver, ISO та ін.
47

Wei, Guoke, Jinliang Wang, and Yu Chen. "Electromagnetic enhancement of ordered silver nanorod arrays evaluated by discrete dipole approximation." Beilstein Journal of Nanotechnology 6 (March 9, 2015): 686–96. http://dx.doi.org/10.3762/bjnano.6.69.

Повний текст джерела
Анотація:
The enhancement factor (EF) of surface-enhanced Raman scattering (SERS) from two-dimensional (2D) hexagonal silver nanorod (AgNR) arrays were investigated in terms of electromagnetic (EM) mechanism by using the discrete dipole approximation (DDA) method. The dependence of EF on several parameters, i.e., structure, length, excitation wavelength, incident angle and polarization, and gap size has been investigated. “Hotspots” were found distributed in the gaps between adjacent nanorods. Simulations of AgNR arrays of different lengths revealed that increasing the rod length from 374 to 937 nm (aspect ratio from 2.0 to 5.0) generated more “hotspots” but not necessarily increased EF under both 514 and 532 nm excitation. A narrow lateral gap (in the incident plane) was found to result in strong EF, while the dependence of EF on the diagonal gap (out of the incident plane) showed an oscillating behavior. The EF of the array was highly dependent on the angle and polarization of the incident light. The structure of AgNR and the excitation wavelength were also found to affect the EF. The EF of random arrays was stronger than that of an ordered one with the same average gap of 21 nm, which could be explained by the exponential dependence of EF on the lateral gap size. Our results also suggested that absorption rather than extinction or scattering could be a good indicator of EM enhancement. It is expected that the understanding of the dependence of local field enhancement on the structure of the nanoarrays and incident excitations will shine light on the optimal design of efficient SERS substrates and improved performance.
Стилі APA, Harvard, Vancouver, ISO та ін.
48

Keller, Adrian, Jenny Rackwitz, Emilie Cauët, Jacques Liévin, Thomas Körzdörfer, Alexandru Rotaru, Kurt V. Gothelf, Flemming Besenbacher, and Ilko Bald. "Sequence dependence of electron-induced DNA strand breakage revealed by DNA nanoarrays." Scientific Reports 4, no. 1 (December 9, 2014). http://dx.doi.org/10.1038/srep07391.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
49

Huang, Da, Mark Freeley, and Matteo Palma. "DNA-Mediated Patterning of Single Quantum Dot Nanoarrays: A Reusable Platform for Single-Molecule Control." Scientific Reports 7, no. 1 (March 28, 2017). http://dx.doi.org/10.1038/srep45591.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
50

Mao, Miao, Zhun Lin, Liang Chen, Zhengyu Zou, Jie Zhang, Quanhao Dou, Jiacheng Wu, et al. "Modular DNA-Origami-Based Nanoarrays Enhance Cell Binding Affinity through the “Lock-and-Key” Interaction." Journal of the American Chemical Society, February 22, 2023. http://dx.doi.org/10.1021/jacs.2c13825.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
Ми пропонуємо знижки на всі преміум-плани для авторів, чиї праці увійшли до тематичних добірок літератури. Зв'яжіться з нами, щоб отримати унікальний промокод!

До бібліографії