Статті в журналах з теми "DNA Encoded Library"
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Hackler, Amber L., Forrest G. FitzGerald, Vuong Q. Dang, Alexander L. Satz, and Brian M. Paegel. "Off-DNA DNA-Encoded Library Affinity Screening." ACS Combinatorial Science 22, no. 1 (December 12, 2019): 25–34. http://dx.doi.org/10.1021/acscombsci.9b00153.
Повний текст джерелаBrunschweiger, Andreas. "A DNA-encoded library special issue." Bioorganic & Medicinal Chemistry 56 (February 2022): 116582. http://dx.doi.org/10.1016/j.bmc.2021.116582.
Повний текст джерелаCochrane, Wesley G., Marie L. Malone, Vuong Q. Dang, Valerie Cavett, Alexander L. Satz, and Brian M. Paegel. "Activity-Based DNA-Encoded Library Screening." ACS Combinatorial Science 21, no. 5 (March 18, 2019): 425–35. http://dx.doi.org/10.1021/acscombsci.9b00037.
Повний текст джерелаZhang, Y., and M. A. Clark. "Design concepts for DNA-encoded library synthesis." Bioorganic & Medicinal Chemistry 41 (July 2021): 116189. http://dx.doi.org/10.1016/j.bmc.2021.116189.
Повний текст джерелаShin, Min Hyeon, Kang Ju Lee, and Hyun-Suk Lim. "DNA-Encoded Combinatorial Library of Macrocyclic Peptoids." Bioconjugate Chemistry 30, no. 11 (October 30, 2019): 2931–38. http://dx.doi.org/10.1021/acs.bioconjchem.9b00628.
Повний текст джерелаCochrane, Wesley G., Patrick R. Fitzgerald, and Brian M. Paegel. "Antibacterial Discovery via Phenotypic DNA-Encoded Library Screening." ACS Chemical Biology 16, no. 12 (November 20, 2021): 2752–56. http://dx.doi.org/10.1021/acschembio.1c00714.
Повний текст джерелаShen, Yurong, Guanyu Yang, Wei Huang, Alex Shaginian, Qian Lin, Jinqiao Wan, Jin Li, Yun Deng, and Guansai Liu. "Photoredox Deaminative Alkylation in DNA-Encoded Library Synthesis." Organic Letters 24, no. 14 (April 1, 2022): 2650–54. http://dx.doi.org/10.1021/acs.orglett.2c00697.
Повний текст джерелаKómár, Péter, and Marko Kalinić. "Denoising DNA Encoded Library Screens with Sparse Learning." ACS Combinatorial Science 22, no. 8 (June 12, 2020): 410–21. http://dx.doi.org/10.1021/acscombsci.0c00007.
Повний текст джерелаDing, Yun, Jing Chai, Paolo A. Centrella, Chenaimwoyo Gondo, Jennifer L. DeLorey, and Matthew A. Clark. "Development and Synthesis of DNA-Encoded Benzimidazole Library." ACS Combinatorial Science 20, no. 5 (April 12, 2018): 251–55. http://dx.doi.org/10.1021/acscombsci.8b00009.
Повний текст джерелаOnda, Yuichi, Gabriele Bassi, Abdullah Elsayed, Franziska Ulrich, Sebastian Oehler, Louise Plais, Jörg Scheuermann, and Dario Neri. "A DNA‐Encoded Chemical Library Based on Peptide Macrocycles." Chemistry – A European Journal 27, no. 24 (March 18, 2021): 7160–67. http://dx.doi.org/10.1002/chem.202005423.
Повний текст джерелаGoodnow, Robert. "DNA-Encoded Library Technology (DELT) After a Quarter Century." SLAS DISCOVERY: Advancing the Science of Drug Discovery 23, no. 5 (May 21, 2018): 385–86. http://dx.doi.org/10.1177/2472555218766250.
Повний текст джерелаDawadi, Surendra, Nicholas Simmons, Gabriella Miklossy, Kurt M. Bohren, John C. Faver, Melek Nihan Ucisik, Pranavanand Nyshadham, Zhifeng Yu, and Martin M. Matzuk. "Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library." Proceedings of the National Academy of Sciences 117, no. 29 (July 8, 2020): 16782–89. http://dx.doi.org/10.1073/pnas.2005447117.
Повний текст джерелаEidam, Oliv, and Alexander L. Satz. "Analysis of the productivity of DNA encoded libraries." MedChemComm 7, no. 7 (2016): 1323–31. http://dx.doi.org/10.1039/c6md00221h.
Повний текст джерелаReddavide, Francesco V., Meiying Cui, Weilin Lin, Naiqiang Fu, Stephan Heiden, Helena Andrade, Michael Thompson, and Yixin Zhang. "Second generation DNA-encoded dynamic combinatorial chemical libraries." Chemical Communications 55, no. 26 (2019): 3753–56. http://dx.doi.org/10.1039/c9cc01429b.
Повний текст джерелаGoodnow Jr., Robert A., and Christopher P. Davie. "2015 First Boston Symposium of Encoded Library Platforms." MedChemComm 7, no. 7 (2016): 1268–70. http://dx.doi.org/10.1039/c6md90023b.
Повний текст джерелаShi, Ying, Yan-ran Wu, Jian-qiang Yu, Wan-nian Zhang, and Chun-lin Zhuang. "DNA-encoded libraries (DELs): a review of on-DNA chemistries and their output." RSC Advances 11, no. 4 (2021): 2359–76. http://dx.doi.org/10.1039/d0ra09889b.
Повний текст джерелаDumelin, Christoph E., Jörg Scheuermann, Samu Melkko, and Dario Neri. "Selection of Streptavidin Binders from a DNA-Encoded Chemical Library." Bioconjugate Chemistry 17, no. 2 (March 2006): 366–70. http://dx.doi.org/10.1021/bc050282y.
Повний текст джерелаSatz, Alexander L. "DNA Encoded Library Selections and Insights Provided by Computational Simulations." ACS Chemical Biology 10, no. 10 (July 27, 2015): 2237–45. http://dx.doi.org/10.1021/acschembio.5b00378.
Повний текст джерелаZhu, Zhengrong, Alex Shaginian, LaShadric C. Grady, Thomas O’Keeffe, Xiangguo E. Shi, Christopher P. Davie, Graham L. Simpson, et al. "Design and Application of a DNA-Encoded Macrocyclic Peptide Library." ACS Chemical Biology 13, no. 1 (December 4, 2017): 53–59. http://dx.doi.org/10.1021/acschembio.7b00852.
Повний текст джерелаFaver, John C., Kevin Riehle, David R. Lancia, Jared B. J. Milbank, Christopher S. Kollmann, Nicholas Simmons, Zhifeng Yu, and Martin M. Matzuk. "Quantitative Comparison of Enrichment from DNA-Encoded Chemical Library Selections." ACS Combinatorial Science 21, no. 2 (January 23, 2019): 75–82. http://dx.doi.org/10.1021/acscombsci.8b00116.
Повний текст джерелаDumelin, Christoph E, Sabrina Trüssel, Fabian Buller, Eveline Trachsel, Frank Bootz, Yixin Zhang, Luca Mannocci, et al. "A Portable Albumin Binder from a DNA-Encoded Chemical Library." Angewandte Chemie 120, no. 17 (April 14, 2008): 3240–45. http://dx.doi.org/10.1002/ange.200704936.
Повний текст джерелаStress, Cedric J., Basilius Sauter, Lukas A. Schneider, Timothy Sharpe, and Dennis Gillingham. "A DNA‐Encoded Chemical Library Incorporating Elements of Natural Macrocycles." Angewandte Chemie International Edition 58, no. 28 (July 8, 2019): 9570–74. http://dx.doi.org/10.1002/anie.201902513.
Повний текст джерелаEdwards, Paul. "Design and synthesis of a novel DNA-encoded chemical library." Drug Discovery Today 15, no. 15-16 (August 2010): 690–91. http://dx.doi.org/10.1016/j.drudis.2010.06.013.
Повний текст джерелаDumelin, Christoph E, Sabrina Trüssel, Fabian Buller, Eveline Trachsel, Frank Bootz, Yixin Zhang, Luca Mannocci, et al. "A Portable Albumin Binder from a DNA-Encoded Chemical Library." Angewandte Chemie International Edition 47, no. 17 (April 14, 2008): 3196–201. http://dx.doi.org/10.1002/anie.200704936.
Повний текст джерелаPrice, Alexander K., and Brian M. Paegel. "Considerations for Achieving Maximized DNA Recovery in Solid-Phase DNA-Encoded Library Synthesis." ACS Combinatorial Science 22, no. 11 (August 6, 2020): 649–55. http://dx.doi.org/10.1021/acscombsci.0c00101.
Повний текст джерелаXia, Bing, G. Joseph Franklin, Xiaojie Lu, Katie L. Bedard, LaShadric C. Grady, Jennifer D. Summerfield, Eric X. Shi, et al. "DNA-Encoded Library Hit Confirmation: Bridging the Gap Between On-DNA and Off-DNA Chemistry." ACS Medicinal Chemistry Letters 12, no. 7 (June 3, 2021): 1166–72. http://dx.doi.org/10.1021/acsmedchemlett.1c00156.
Повний текст джерелаJi, Yue, Dongliang Dai, Huadong Luo, Simin Shen, Jing Fan, Zhao Wang, Min Chen, et al. "C–S Coupling of DNA-Conjugated Aryl Iodides for DNA-Encoded Chemical Library Synthesis." Bioconjugate Chemistry 32, no. 4 (March 15, 2021): 685–89. http://dx.doi.org/10.1021/acs.bioconjchem.1c00076.
Повний текст джерелаReiher, Christopher A., David P. Schuman, Nicholas Simmons, and Scott E. Wolkenberg. "Trends in Hit-to-Lead Optimization Following DNA-Encoded Library Screens." ACS Medicinal Chemistry Letters 12, no. 3 (February 11, 2021): 343–50. http://dx.doi.org/10.1021/acsmedchemlett.0c00615.
Повний текст джерелаGuasch, Laura, Michael Reutlinger, Daniel Stoffler, and Moreno Wichert. "Augmenting Chemical Space with DNA-encoded Library Technology and Machine Learning." CHIMIA International Journal for Chemistry 75, no. 1 (February 28, 2021): 105–7. http://dx.doi.org/10.2533/chimia.2021.105.
Повний текст джерелаKrumb, Matthias, Lisa Marie Kammer, Shorouk O. Badir, María Jesús Cabrera-Afonso, Victoria E. Wu, Minxue Huang, Adam Csakai, Lisa A. Marcaurelle, and Gary A. Molander. "Photochemical C–H arylation of heteroarenes for DNA-encoded library synthesis." Chemical Science 13, no. 4 (2022): 1023–29. http://dx.doi.org/10.1039/d1sc05683b.
Повний текст джерелаPark, Jun Hyung, Hee Myeong Wang, Min Hyeon Shin, and Hyun‐Suk Lim. "Synthesis of a DNA‐Encoded Library of Pyrrolo[2,3 ‐d ]pyrimidines." Bulletin of the Korean Chemical Society 42, no. 4 (February 8, 2021): 691–98. http://dx.doi.org/10.1002/bkcs.12243.
Повний текст джерелаZhou, Yu, Chen Li, Jianzhao Peng, Liangxu Xie, Ling Meng, Qingrong Li, Jianfu Zhang, et al. "DNA-Encoded Dynamic Chemical Library and Its Applications in Ligand Discovery." Journal of the American Chemical Society 140, no. 46 (November 2018): 15859–67. http://dx.doi.org/10.1021/jacs.8b09277.
Повний текст джерелаAhn, Seungkirl, Alem W. Kahsai, Biswaranjan Pani, Qin-Ting Wang, Shuai Zhao, Alissa L. Wall, Ryan T. Strachan, et al. "Allosteric “beta-blocker” isolated from a DNA-encoded small molecule library." Proceedings of the National Academy of Sciences 114, no. 7 (January 27, 2017): 1708–13. http://dx.doi.org/10.1073/pnas.1620645114.
Повний текст джерелаMacConnell, Andrew B., Alexander K. Price, and Brian M. Paegel. "An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening." ACS Combinatorial Science 19, no. 3 (February 22, 2017): 181–92. http://dx.doi.org/10.1021/acscombsci.6b00192.
Повний текст джерелаGötte, Katharina, Silvia Chines, and Andreas Brunschweiger. "Reaction development for DNA-encoded library technology: From evolution to revolution?" Tetrahedron Letters 61, no. 22 (May 2020): 151889. http://dx.doi.org/10.1016/j.tetlet.2020.151889.
Повний текст джерелаPhelan, James P., Simon B. Lang, Jaehoon Sim, Simon Berritt, Andrew J. Peat, Katelyn Billings, Lijun Fan, and Gary A. Molander. "Open-Air Alkylation Reactions in Photoredox-Catalyzed DNA-Encoded Library Synthesis." Journal of the American Chemical Society 141, no. 8 (February 12, 2019): 3723–32. http://dx.doi.org/10.1021/jacs.9b00669.
Повний текст джерелаKunig, Verena, Marco Potowski, Anne Gohla, and Andreas Brunschweiger. "DNA-encoded libraries – an efficient small molecule discovery technology for the biomedical sciences." Biological Chemistry 399, no. 7 (June 27, 2018): 691–710. http://dx.doi.org/10.1515/hsz-2018-0119.
Повний текст джерелаGironda-Martínez, Adrián, Dario Neri, Florent Samain, and Etienne J. Donckele. "DNA-Compatible Diazo-Transfer Reaction in Aqueous Media Suitable for DNA-Encoded Chemical Library Synthesis." Organic Letters 21, no. 23 (November 20, 2019): 9555–58. http://dx.doi.org/10.1021/acs.orglett.9b03726.
Повний текст джерелаZhou, Yu, Jianzhao Peng, Wenyin Shen, and Xiaoyu Li. "Psoralen as an interstrand DNA crosslinker in the selection of DNA-Encoded dynamic chemical library." Biochemical and Biophysical Research Communications 533, no. 2 (December 2020): 215–22. http://dx.doi.org/10.1016/j.bbrc.2020.04.033.
Повний текст джерелаTian, Xia, Gregory S. Basarab, Nidhal Selmi, Thierry Kogej, Ying Zhang, Matthew Clark, and Robert A. Goodnow Jr. "Development and design of the tertiary amino effect reaction for DNA-encoded library synthesis." MedChemComm 7, no. 7 (2016): 1316–22. http://dx.doi.org/10.1039/c6md00088f.
Повний текст джерелаArico-Muendel, Christopher C. "From haystack to needle: finding value with DNA encoded library technology at GSK." MedChemComm 7, no. 10 (2016): 1898–909. http://dx.doi.org/10.1039/c6md00341a.
Повний текст джерелаLee, Kang Ju, Geul Bang, Yong Wook Kim, Min Hyeon Shin, and Hyun-Suk Lim. "Design and synthesis of a DNA-encoded combinatorial library of bicyclic peptoids." Bioorganic & Medicinal Chemistry 48 (October 2021): 116423. http://dx.doi.org/10.1016/j.bmc.2021.116423.
Повний текст джерелаChen, Qiuxia, Xuemin Cheng, Lifang Zhang, Xianyang Li, Purui Chen, Jian Liu, Lanjun Zhang, Hong Wei, Zhonghan Li, and Dengfeng Dou. "Exploring the Lower Limit of Individual DNA-Encoded Library Molecules in Selection." SLAS DISCOVERY: Advancing the Science of Drug Discovery 25, no. 5 (December 20, 2019): 523–29. http://dx.doi.org/10.1177/2472555219893949.
Повний текст джерелаMelkko, Samu, Yixin Zhang, Christoph E Dumelin, Jörg Scheuermann, and Dario Neri. "Isolation of High-Affinity Trypsin Inhibitors from a DNA-Encoded Chemical Library." Angewandte Chemie 119, no. 25 (June 18, 2007): 4755–58. http://dx.doi.org/10.1002/ange.200700654.
Повний текст джерелаMelkko, Samu, Yixin Zhang, Christoph E Dumelin, Jörg Scheuermann, and Dario Neri. "Isolation of High-Affinity Trypsin Inhibitors from a DNA-Encoded Chemical Library." Angewandte Chemie International Edition 46, no. 25 (June 18, 2007): 4671–74. http://dx.doi.org/10.1002/anie.200700654.
Повний текст джерелаWen, Xin, Xinyuan Wu, Rui Jin, and Xiaojie Lu. "Privileged heterocycles for DNA-encoded library design and hit-to-lead optimization." European Journal of Medicinal Chemistry 248 (February 2023): 115079. http://dx.doi.org/10.1016/j.ejmech.2022.115079.
Повний текст джерелаChan, Alix I., Lynn M. McGregor, Tara Jain, and David R. Liu. "Discovery of a Covalent Kinase Inhibitor from a DNA-Encoded Small-Molecule Library × Protein Library Selection." Journal of the American Chemical Society 139, no. 30 (July 20, 2017): 10192–95. http://dx.doi.org/10.1021/jacs.7b04880.
Повний текст джерелаŠkopić, M. Klika, O. Bugain, K. Jung, S. Onstein, S. Brandherm, T. Kalliokoski, and A. Brunschweiger. "Design and synthesis of DNA-encoded libraries based on a benzodiazepine and a pyrazolopyrimidine scaffold." MedChemComm 7, no. 10 (2016): 1957–65. http://dx.doi.org/10.1039/c6md00243a.
Повний текст джерелаPetersen, L. K., P. Blakskjær, A. Chaikuad, A. B. Christensen, J. Dietvorst, J. Holmkvist, S. Knapp та ін. "Novel p38α MAP kinase inhibitors identified from yoctoReactor DNA-encoded small molecule library". MedChemComm 7, № 7 (2016): 1332–39. http://dx.doi.org/10.1039/c6md00241b.
Повний текст джерелаOttl, Johannes, Lukas Leder, Jonas V. Schaefer, and Christoph E. Dumelin. "Encoded Library Technologies as Integrated Lead Finding Platforms for Drug Discovery." Molecules 24, no. 8 (April 25, 2019): 1629. http://dx.doi.org/10.3390/molecules24081629.
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