Увійти

Готові списки джерел за темами / DNA Effect of radiation on / Дисертації

Щоб переглянути інші типи публікацій з цієї теми, перейдіть за посиланням: DNA Effect of radiation on.

Дисертації з теми "DNA Effect of radiation on"

Автор: Grafiati

Опубліковано: 4 червня 2021

Оновлено: 1 лютого 2022

Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями

Оберіть тип джерела:

Ознайомтеся з топ-50 дисертацій для дослідження на тему "DNA Effect of radiation on".

Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.

Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.

Переглядайте дисертації для різних дисциплін та оформлюйте правильно вашу бібліографію.

1

MacPhail, Susan Helen. "Effect of intercellular contact on radiation-induced DNA damage." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/27986.

Повний текст джерела

Анотація:

Chinese hamster V79-171B cells grown for about 24 hours in suspension culture display increased resistance to cell killing by ionizing radiation compared with cells grown as monolayers, an observation originally termed the "contact effect". More recently, development of that resistance was shown to be accompanied by changes in the conformation of the DNA which reduce its denaturation rate in high salt/weak alkali. These changes in DNA conformation, mediated by the cellular micro-environment, appear to be responsible for the contact effect. The conditions necessary for the development of the e

Стилі APA, Harvard, Vancouver, ISO та ін.

2

Bajinskis, Ainars. "Studies of DNA repair strategies in response to complex DNA damages." Doctoral thesis, Stockholms universitet, Institutionen för genetik, mikrobiologi och toxikologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-72472.

Повний текст джерела

Анотація:

The main aim of this thesis was to study the role of the indirect actions of γ-rays and α-particles on the complexity of primary DNA damages and the repair fidelity of major DNA repair pathways: non-homologous end joining (NHEJ), homologous recombination repair (HRR) and base excision repair (BER). The complexity of radiation-induced damages increases and the proximity between damages decreases with increasing LET due to formation of ionization clusters along the particle track. The complexity of damages formed can be modified by the free radical scavenger dimethyl sulfoxide (DMSO). In additio

Стилі APA, Harvard, Vancouver, ISO та ін.

3

Morabito, Brian Joseph. "Quantitating radiation induced DNA breaks by capillary electrophoresis." Thesis, Georgia Institute of Technology, 1997. http://hdl.handle.net/1853/16339.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

4

Braddock, M. "Effects of radiation on DNA." Thesis, University of Salford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356177.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

5

Verma, Meera Mary. "On the effect of UV-irradiation on DNA replication in Escherichia coli." Title page, contents and summary only, 1985. http://web4.library.adelaide.edu.au/theses/09PH/09phv522.pdf.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

6

Byrne, Shaun Edward. "An investigation into the processing of ionising radiation induced clustered DNA damage sites using mammalian cell extracts." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670082.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

7

Roos, Wynand Paul. "The influence of DNA damage, DNA repair and chromatin structure on radiosensitivity." Thesis, Stellenbosch : Stellenbosch University, 2001. http://hdl.handle.net/10019.1/52540.

Повний текст джерела

Анотація:

Thesis (PhD)--Stellenbosch University, 2001.<br>ENGLISH ABSTRACT: The factors which control radiosensitivity are of vital importance for the understanding of cell inactivation and for cancer therapy. Cell cycle blocks, total induced DNA damage, DNA repair, apoptosis and chromatin structure are likely to playa role in the responses leading to cell death. I have examined aspects of irradiation-induced G2/M blocks in DNA damage and repair. In HT29, L132 and ATs4 cells the total amount of induced DNA damage by isodoses of 4.5 Gy, 5 Gy and 2 Gy was found to be 14 %, 14 % and 12 % respective

Стилі APA, Harvard, Vancouver, ISO та ін.

8

Starrs, Sharon Margaret. "Molecular mechanisms of DNA photodamage." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314222.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

9

Sweeney, Marion Carol. "The effects of gamma radiation on DNA." Thesis, University of Leicester, 1986. http://hdl.handle.net/2381/33943.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

10

Elsy, David. "The effects of gamma-radiation on DNA." Thesis, University of Leicester, 1991. http://hdl.handle.net/2381/33664.

Повний текст джерела

Анотація:

In this study gamma-radiation-induced DNA strand breaks have been investigated using two systems: a plasmid-based assay, and a whole nuclei-, or whole cell-based, alkaline filter elution assay. Addition of alkali metal halides to DNA irradiated under frozen aqueous conditions were observed to have an effect on the radiosensitivity of the DNA. This, effect, which was not observed with DNA irradiated under fluid aqueous conditions, would appear to be due to two components; a physical component, and a chemical component which is dependent on the anions used. Addition of alkali metal halides appea

Стилі APA, Harvard, Vancouver, ISO та ін.

11

Alvarado, Chacón Fresia. "Ion induced radiation damage on the molecular level." [S.l. : Groningen : s.n. ; University Library of Groningen] [Host], 2007. http://irs.ub.rug.nl/ppn/305192396.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

12

Camacho, Inês Sofia Cortes Eusébio. "Effects of UV radiation exposure on DNA and DNA repair enzymes." Master's thesis, Faculdade de Ciências e Tecnologia, 2012. http://hdl.handle.net/10362/8263.

Повний текст джерела

Анотація:

Dissertação para obtenção do Grau de Mestre em Biotecnologia<br>DNA integrity in the cell is under constant threat from damaging agents of endogenous or exogenous origin, such as UV light, ionizing radiation and oxidative stress. Although the effects of these carcinogens on DNA have been extensively studied, very little is known about their effect on DNA repair enzymes. The aim of the present work was the study of the effect of UV radiation on E. coli Endonuclease III, a DNA glycosylase belonging to base excision repair system. This enzyme was homologously overexpressed and then purified wi

Стилі APA, Harvard, Vancouver, ISO та ін.

13

Kabilan, Usha. "Studying the Effect of Low Doses of Ionization Radiation on Senescence in Human Lung Fibroblasts." Thesis, Université d'Ottawa / University of Ottawa, 2020. http://hdl.handle.net/10393/40982.

Повний текст джерела

Анотація:

The exposure to high doses of ionizing radiation (>5Gy) is unequivocally associated with increased cancer risk. However, there is substantial experimental evidence showing that in response to low doses of ionizing radiation (LDR: <100mGy), cells and organisms are benefitted with delayed ageing, improved immunity and reduced cancer growth. These intriguing findings have proposed the “Radiation Hormesis” hypothesis. Herein, I studied the senescence effects of LDR exposure to normal human HFL1 cells and examined transcriptional changes. I found that HFL1 cells exposed to 10 mGy of gamma radiation

Стилі APA, Harvard, Vancouver, ISO та ін.

14

Bykov, Vladimir J. "UV-induced DNA damage in humans /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3345-6/.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

15

Malone, Mark E. "The effect of ionising radiation on DNA and its constituents : an EPR study." Thesis, University of Leicester, 1993. http://hdl.handle.net/2381/33797.

Повний текст джерела

Анотація:

This thesis was concerned with the effects of ?-radiation and UV-photoionisation on DNA an its constituents at 77 K. In particular, the work has concentrated on the radical-anion and radical-cation centres, with a view to obtaining a better understanding of the so-called direct mechanism of radiation damage. The ?-irradiation of DNA and its constituents in aqueous LiCl glasses suppresses radical cation formation and gives rise to well resolved radical anion spectra which can be readily studied by EPR spectroscopy. The nucleotides of adenine, cytosine, guanine and cytosine all yield base centre

Стилі APA, Harvard, Vancouver, ISO та ін.

16

Allman, Amy Jane. "Effects of UV radiation on Marfan syndrome cells in culture." Virtual Press, 1993. http://liblink.bsu.edu/uhtbin/catkey/879841.

Повний текст джерела

Анотація:

Ultraviolet radiation causes an alteration in DNA by modifying neighboring thymine bases resulting in the formation of a dimer. These dimers block the processes of transcription and translation and ultimately no protein is synthesized and the cell dies. However, DNA repair mechanisms correct this damage by excising the dimer from the DNA strand and inserting replacement bases which are joined to the original strand by DNA ligase. This allows transcription to resume and ultimately protein synthesis to take place.This research focused on determining the DNA damage and subsequent repair levels in

Стилі APA, Harvard, Vancouver, ISO та ін.

17

Fulford, Jonathan. "Quantification of complex DNA damage by ionising radiation : an experimental and theoretical approach." Thesis, Brunel University, 2000. http://bura.brunel.ac.uk/handle/2438/5782.

Повний текст джерела

Анотація:

Ionising radiation potentially produces a broad spectrum of damage in DNA including single and double strand breaks (ssb and dsb) and base damages. It has been hypothesised that sites of complex damage within cellular DNA have particular biological significance due to an associated decreased efficiency in repair. The aim of this study is to gain further understanding of the formation of complex DNA damage. Irradiations of plasmid DNA illustrate that an increase in ionising density of the radiation results in a decrease in ssb yields/Gy but an increase in dsb per ssb, indicative of an increase

Стилі APA, Harvard, Vancouver, ISO та ін.

18

Ladin, Loren Guerrero 1959. "Effect of ultraviolet light on reproduction in Hydra littoralis." Thesis, The University of Arizona, 1989. http://hdl.handle.net/10150/277085.

Повний текст джерела

Анотація:

The "DNA Damage Hypothesis" pertaining to the evolution of sex was tested using Hydra littoralis. DNA damage was produced by irradiating whole live hydra with ultraviolet light. A curve of uv light dosage vs. survival was constructed. Estimations of threshold fluence and LD50 were made from the survival curve. In four separate experiments, using various combinations of environmental temperatures, uv doses, and number of doses, frequencies of asexual and sexual reproduction were observed and compared. The hydra that received uv treatments did not show an increase in the consequent amount of sex

Стилі APA, Harvard, Vancouver, ISO та ін.

19

Baker, Mike, and University of Lethbridge Faculty of Arts and Science. "Role of epigenetic changes in direct and indirect radiation effects." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2008, 2008. http://hdl.handle.net/10133/650.

Повний текст джерела

Анотація:

For over 100 years, cancer radiation therapy has provided patients with increased survival rates. Despite this success, radiation exposure poses a threat to the progeny of exposed parents. It causes transgenerational genome instability that is linked to transgenerational carcinogenesis. The exact mechanisms in which this instability occurs have yet to be discovered. Current evidence points to their epigenetic nature, specifically changes in DNA methylation. Using mouse and rat models, this thesis investigated the transgenerational effects of radiation in the offspring from parents who received

Стилі APA, Harvard, Vancouver, ISO та ін.

20

Tamminga, Jan, and University of Lethbridge Faculty of Arts and Science. "Radiation-induced epigenome deregulation in the male germline." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2008, 2008. http://hdl.handle.net/10133/746.

Повний текст джерела

Анотація:

Approximately 45% of men will develop cancer during their lifetime; some of which will be of reproductive age (Canadian Cancer Society, 2008). Current advances in treatment regimens such as radiotherapy have significantly lowered cancer-related mortality rates; however, one major quality-of-life issue in cancer survivors is the ability to produce healthy offspring. Exposure to ionizing radiation (IR) leads to genomic instability in the germline, and further to transgeneration genome instability in unexposed offspring of preconceptionally exposed parents. The results presented in this thesis de

Стилі APA, Harvard, Vancouver, ISO та ін.

21

VALGODE, FLAVIA G. S. "Avaliação do dano radioinduzido, capacidade de reparo e morte celular em células humanas tumorais (T-47D e MCF-7) e nao tumorais (MCF-10) de mama." reponame:Repositório Institucional do IPEN, 2008. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11710.

Повний текст джерела

Анотація:

Made available in DSpace on 2014-10-09T12:54:58Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:07:14Z (GMT). No. of bitstreams: 0<br>Dissertacao (Mestrado)<br>IPEN/D<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP

Стилі APA, Harvard, Vancouver, ISO та ін.

22

Gonon, Géraldine. "Space radiation-induced bystander effect : kinetics of biologic responses, mechanisms, and significance of secondary radiations." Phd thesis, Université de Franche-Comté, 2011. http://tel.archives-ouvertes.fr/tel-00987717.

Повний текст джерела

Анотація:

Widespread evidence indicates that exposure of cell cultures to α particles results in significant biological changes in both the irradiated and non-irradiated bystander cells in the population. The induction of non-targeted biological responses in cell cultures exposed to low fluences of high charge (Z) and high energy (E) particles is relevant to estimates of the health risks of space radiation and to radiotherapy. Here, we investigated the mechanisms underlying the induction of stressful effects in confluent normal human fibroblast cultures exposed to low fluences of 1000 MeV/u iron ions (l

Стилі APA, Harvard, Vancouver, ISO та ін.

23

Logan, Ian D. "The effect of low intensity laser irradiation and low level, low LET ionising radiation on DNA within mammalian cells." Thesis, University of Ulster, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338280.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

24

Boon, P. J. "ESR studies on the effects of ionizing radiation on DNA plus additives." Thesis, University of Leicester, 1985. http://hdl.handle.net/2381/34020.

Повний текст джерела

Анотація:

In this study the direct effect of ionising radiation on DNA plus additives has been studied using both ESR spectroscopy and plasmid DMA (for strand break analysis). The primary radicals were identified as the thymine radical-anion, T', and guanine radical-cation, G'*'. Under normal conditions these were formed in approximately equal yields as defined by careful computer simulations. Certain additives such as oxygen, nitroimidazoles, silver ions and the rest of the nuclear complement (i.e. RNA and histone proteins) , were added to study their effects on the relative yields of T" and G". In all

Стилі APA, Harvard, Vancouver, ISO та ін.

25

Koturbash, Igor, and University of Lethbridge Faculty of Arts and Science. "Molecular mechanisms of radiation-induced bystander effects in vivo." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2008, 2008. http://hdl.handle.net/10133/664.

Повний текст джерела

Анотація:

Ionizing radiation (IR), along with being an important diagnostic and treatment modality, is a potent tumor-causing agent, and the risk of secondary radiation treatment-related cancers is a growing clinical problem. Now some studies propose to link secondary radiation-induced cancers to an enigmatic phenomenon of bystander effects, whereby the exposed cells send signal damage and distress to their naïve neighbors and result in genome destabilization and carcinogenesis. Yet, no data existed on the bystander effects in an organ other than an exposed one. With this in mind, we focused on the anal

Стилі APA, Harvard, Vancouver, ISO та ін.

26

Carpenter, Lucy. "DNA repair pathways involved in determining the level of cytotoxicity of environmentally relevant UV radiation." Thesis, Lancaster University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340566.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

27

Jones, George Donal Dransfield. "The direct effects of ionizing radiation on DNA and its higher ordered structures." Thesis, University of Leicester, 1987. http://hdl.handle.net/2381/9691.

Повний текст джерела

Анотація:

This thesis investigates the effects of ionizing radiation on frozen aqueous solutions of DNA using e.s.r. spectroscopy and a plasmid (pBR322) strand break assay. To elucidate the mechanisms subsequent to primary ionic radical formation (G˙+ and T˙¯), additives that influence the radiolytic processes were included prior to irradiation. The presence of hydrogen peroxide (Chapter Three) switched the mechanism from direct damage to a pathway in part mediated through oxygen centred radicals (˙OH, HO˙2) and resulted in a modest increase in the number of strand breaks (i.e. radiosensitization). E.s.

Стилі APA, Harvard, Vancouver, ISO та ін.

28

McClymont, John Douglas. "ESR studies of the effects of complexing agents on radiation damage in DNA." Thesis, University of Leicester, 1990. http://hdl.handle.net/2381/33802.

Повний текст джерела

Анотація:

The effects of a range of complexing agents on the radiation damage routes in frozen aqueous DNA have been analyzed by ESR techniques in a semi-quantitative way. Establishment of additive-free DNA standards for this study revealed an ESR pattern different from the four elementary shapes which contributed &sim; 13X of the total spin seen after annealing to 210 K. It is proposed that this represents a population of sugar radicals; hitherto unseen intermediates in additive-free systems between secondary base radicals and strand breaks. The intercalating aminoanthraquinones, mitoxantrone and ameta

Стилі APA, Harvard, Vancouver, ISO та ін.

29

Valente, Marco. "Signalling detection of DNA damage induced by low doses of ionizing radiation in human lymphocytes." Versailles-St Quentin en Yvelines, 2011. http://www.theses.fr/2011VERS0021.

Повний текст джерела

Анотація:

Etude du lien entre radiosensibilité clinique d’un patient et de ses lymphocytes irradiés in vitro dans le but de faire un test prédictif de la radiosensibilité individuelle. La radiosensibilité clinique est quantifiée par les effets secondaires d’une radiothérapie et la sensibilité cellulaire est mesurée grâce à la cinétique d’apparition/disparition des doubles cassures de l’ADN radio-induites (marquées par des foyers gamma-H2AX). Pour rendre ce protocole utilisable en application clinique, on a amélioré la viabilité de l'échantillon et augmenté la vitesse d’analyse. Enfin, nous nous sommes c

Стилі APA, Harvard, Vancouver, ISO та ін.

30

Jones, Matthew Dunford. "Effects of radiation on the Gâ†2/M checkpoint in human tumour cells of differing radiosensitivities." Thesis, University of Liverpool, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.387452.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

31

AQUINO, SIMONE. "Efeitos da radiacao gama no crescimento de Aspergillus flavus produtor de aflatoxinas e no emprego da tecnica da Reacao em Cadeia da Polimerase (PCR) em amostras de graos de milho inoculadas artificialmente." reponame:Repositório Institucional do IPEN, 2003. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11253.

Повний текст джерела

Анотація:

Made available in DSpace on 2014-10-09T12:49:58Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:02:55Z (GMT). No. of bitstreams: 0<br>Dissertacao (Mestrado)<br>IPEN/D<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP

Стилі APA, Harvard, Vancouver, ISO та ін.

32

McRae, Dorothy A., and University of Lethbridge Faculty of Arts and Science. "Radiation induced epigenetic dysregulation in rat mammary gland tissue / Dorothy A. McRae." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2010, 2010. http://hdl.handle.net/10133/2615.

Повний текст джерела

Анотація:

Most breast cancer patients undergo radiation diagnostics and are also treated with radiotherapy. In addition to being an important treatment modality, ionizing radiation (IR) is a potent tumour-causing agent that has been linked to breast cancer development. However, the exact molecular etiology of IR-induced mammary gland carcinogenesis remains unknown. We set out to analyze the role of DNA methylation in mammary gland responses to low dose IR using a well-established rat model. We also studied low dose IR effects on global gene expression and microRNAome. We found that exposure to low, mamm

Стилі APA, Harvard, Vancouver, ISO та ін.

33

Curwen, Gillian B. "G₂ chromosomal radiosensitivity in childhood and adolescent cancer survivors and their offspring." Thesis, St Andrews, 2008. http://hdl.handle.net/10023/425.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

34

Ralph, Emma Louise. "The effects of UV radiation on meiotic DNA replication and Cdt1 stability in fission yeast." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436991.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

35

Bellamy, Michael Bruce. "A double strand DNA break model of photon and electron relative biological effectiveness." Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/47711.

Повний текст джерела

Анотація:

The ICRP recommends a radiation weighting factor of one for all low-LET radiation. However, many experimental studies find inconsistencies between low-LET RBE and the ICRP's current radiation weighting factor. Generally, there is evidence that dependence exists between radiation energy and radiation RBE where lower energy radiations tend to have a greater biological effect than higher energy radiation. Specifically, the radiations of tritium and carbon K-shell x-rays have been studied in numerous experiments and the biological effects of both of these radiations are consistently greater than

Стилі APA, Harvard, Vancouver, ISO та ін.

36

Aquino, Simone. "Efeitos da radiação gama no crescimento de aspergillus flavus produtor de aflatoxinas e no emprego da técnica da reação em cadeia da polimerase (PCR) em amostras de grãos de milho inoculadas artificialmente." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-16042012-105910/.

Повний текст джерела

Анотація:

O presente trabalho teve como objetivos verificar os efeitos da radiação gama em grãos de milho contaminados artificialmente com Aspergillus flavus Link produtor de aflatoxinas; demonstrar a aplicação da técnica da Reação em Cadeia da Polimerase (PCR) no diagnóstico de A. flavus, bem como verificar o efeito da radiação no perfil das bandas de DNA. Vinte amostras de grãos de milho com 200 g cada foram irradiadas individualmente com 20 kGy, para eliminar a contaminação microbiana. Em seguida, as amostras foram inoculadas com A. flavus toxigênico (1 x 106 esporos / ml), incubadas por 15 dias a 25

Стилі APA, Harvard, Vancouver, ISO та ін.

37

Playle, Laura Charlotte. "Radiation-induced apoptosis and cell cycle checkpoints in human colorectal tumour cell lines." Thesis, University of Bristol, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341501.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

38

Milián, Félix Más. "Estudo in vitro dos efeitos radiobiológicos no DNA plasmidial com radiações ionizantes de baixo LET." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/43/43134/tde-04122006-150637/.

Повний текст джерела

Анотація:

O estudo da interação da radiação com moléculas de DNA tem se intensificado nos últimos anos, determinando avanços nas técnicas experimentais e na compreensão teórica desse fenômeno. No entanto, falta ainda um estudo sistemático e com boa precisão da interação de diferentes radiações com o DNA em condições controladas. Neste trabalho desenvolveu-se uma técnica experimental que permite o estudo daquela interação com diferentes radiações, permitindo uma análise quantitativa dos efeitos da radiação sobre o DNA, mais especificamente, da produção de single- e double strand breaks em moléculas de DN

Стилі APA, Harvard, Vancouver, ISO та ін.

39

Gulston, Melanie Katharine. "The effects of the sunscreen chemicals Padimate-O and 2-ethylhexyl-P-methoxycinnamate on DNA." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301520.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

40

Sirzén, Florin. "Molecular aspects of cellular radiosensitivity in small cell lung carcinoma /." Stockholm, 1998. http://diss.kib.ki.se/1998/19981204sirz/.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

41

Saul, Alison Nicole. "Psycho-physiological stress and its effects on ultraviolet light induced inflammation, DNA damage, and skin carcinogenesis." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1172850801.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

42

Terry, Samantha Y. A. "A role for topoisomerase II alpha in chromosome damage in human cell lines." Thesis, University of St Andrews, 2010. http://hdl.handle.net/10023/873.

Повний текст джерела

Анотація:

Human response to ionising radiation (IR) shows a wide variation. This is most clearly seen in the radiation-response of cells as measured by frequencies of chromosomal aberrations. Different frequencies of IR-induced aberrations can be conveniently observed in phytohaemagglutin-stimulated peripheral blood T-lymphocytes from both normal individuals and sporadic cancer cases, in either metaphase chromosomes or as micronuclei in the following cell cycle. Metaphase cells show frequent chromatid breaks, defined as chromatid discontinuities or terminal deletions, if irradiated in the G 2 -phase of

Стилі APA, Harvard, Vancouver, ISO та ін.

43

Valgôde, Flávia Gomes Silva. "Avaliação do dano radioinduzido, capacidade de reparo e morte cecular em células humanas tumorais (T-47D e MCF-7) e não tumorais (MCF-10) de mama." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-16052012-141727/.

Повний текст джерела

Анотація:

Câncer de mama é considerado uma das malignidades mais comuns que acometem as mulheres, representando cerca de uma em cada três de todas as neoplasias femininas. Aproximadamente, 90% dos casos de câncer de mama são esporádicos, atribuíveis aos eventos somáticos e cerca de 10% estão associados com a história familial e destes somente 4-5% são decorrentes de fatores hereditários. Em clínica, a radiação ionizante é a principal ferramenta utilizada no controle do crescimento tumoral, além da intervenção cirúrgica e quimioterapia. Há, no entanto, poucas infomnações no que diz respeito a resposta ce

Стилі APA, Harvard, Vancouver, ISO та ін.

44

Mahee, Durude. "Numerical Simulation and Graphical Illustration of Ionization by Charged Particles as a Tool toward Understanding Biological Effects of Ionizing Radiation." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1535381068931831.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

45

MELO, ANA M. M. de A. "Estudos dos efeitos da radiacao gama de sup60Co sobre larvas de Biomphalaria glabrata (Say,1818)." reponame:Repositório Institucional do IPEN, 1998. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9270.

Повний текст джерела

Анотація:

Made available in DSpace on 2014-10-09T12:25:31Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:02:48Z (GMT). No. of bitstreams: 1 06217.pdf: 3764177 bytes, checksum: 349bd4c7037b4ee83bdc4f4c94ef76e5 (MD5)<br>Tese (Doutoramento)<br>IPEN/T<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP

Стилі APA, Harvard, Vancouver, ISO та ін.

46

Connelly, Sandra J. "Effects of Ultraviolet Radiation (UVR) Induced DNA Damage and Other Ecological Determinants on cryptosporidium Parvum, Giardia Lamblia, and Daphnia spp. in Freshwater Ecosystems." Oxford, Ohio : Miami University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=miami1196353326.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

47

Fourie, Hein. "Microdosimetric studies of Auger electrons from DNA-incorporated 123-I using the micronucleus assay and the Geant4 Monte Carlo simulation tookit." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/95801.

Повний текст джерела

Анотація:

Thesis (MSc)--Stellenbosch University, 2014.<br>ENGLISH ABSTRACT: This study’s focus is on the determination and quantization of radiation damage on a cellular level due to the decay of the Auger electron-emitting 123I and the replication of this energy deposition using Geant4 Monte Carlo simulations. The relatively short half-life of 123I (13.2 hours) makes it ideal for studies of Auger electrons which induce biological damage similar to that of high linear energy transfer radiations, when permitted to deposit their energy in close proximity to DNA. Due to small cellular dimensions, direct do

Стилі APA, Harvard, Vancouver, ISO та ін.

48

von, Koschembahr Anne M. "Endothelin-1 Protects Human Melanocytes from the Photodamaging Effects of Ultraviolet Radiation by Activating the MAP Kinases JNK and p38." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1418909421.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

49

Gould, Richard. "An investigation of scatter removal techniques in paediatric cardiac catheterisation imaging: effects upon radiation dose, image quality DNA integrity and cancer risk." Thesis, Ulster University, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.680142.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

50

TALLARICO, LENITA de F. "Avaliacao dos efeitos toxicos e mutagenicos de amostras ambientais do Rio Tiete na regiao de Suzano em Biomphalaria glabrata (SAY, 1818)." reponame:Repositório Institucional do IPEN, 2009. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9382.

Повний текст джерела

Анотація:

Made available in DSpace on 2014-10-09T12:26:23Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:04:24Z (GMT). No. of bitstreams: 0<br>Tese (Doutoramento)<br>IPEN/T<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP

Стилі APA, Harvard, Vancouver, ISO та ін.

Ми пропонуємо знижки на всі преміум-плани для авторів, чиї праці увійшли до тематичних добірок літератури. Зв'яжіться з нами, щоб отримати унікальний промокод!