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Автор: Grafiati
Опубліковано: 14 березня 2023

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Статті в журналах з теми "Dioxin-like Polychlorinated Biphenyl"

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Bhavsar, Satyendra, Alan Hayton, Eric Reiner, and Don Jackson. "Estimating dioxin-like polychlorinated biphenyl toxic equivalents from total polychlorinated biphenyl measurements in fish." Environmental Toxicology and Chemistry preprint, no. 2007 (2007): 1. http://dx.doi.org/10.1897/06-621.

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Bhavsar, Satyendra P., Alan Hayton, Eric J. Reiner, and Donald A. Jackson. "ESTIMATING DIOXIN-LIKE POLYCHLORINATED BIPHENYL TOXIC EQUIVALENTS FROM TOTAL POLYCHLORINATED BIPHENYL MEASUREMENTS IN FISH." Environmental Toxicology and Chemistry 26, no. 8 (2007): 1622. http://dx.doi.org/10.1897/06-621r.1.

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Mikołajczyk, Szczepan, Małgorzata Warenik-Bany, Sebastian Maszewski, and Marek Pajurek. "Farmed fish as a source of dioxins and PCBs for Polish consumers." Journal of Veterinary Research 64, no. 3 (August 28, 2020): 427–31. http://dx.doi.org/10.2478/jvetres-2020-0054.

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AbstractIntroductionThis paper reports polychlorinated dibenzo-p-dioxin (PCDD), polychlorinated dibenzofuran (PCDF), and polychlorinated biphenyl (PCB) concentrations in fish collected from Polish and Vietnamese farms and the related risk for consumers.Material and MethodsAltogether, 160 samples were analysed using an isotope dilution technique with high-resolution gas chromatography coupled with high-resolution mass spectrometry (HRGC-HRMS). To characterise the potential health risk associated with PCDD/F and dioxin-like polychlorinated biphenyl (DL-PCB) intake, doses ingested in two 100 g portions of fish by adults and children were calculated and expressed as the percentage of the tolerable weekly intake (TWI) newly established by the EFSA in November 2018 at 2 pg WHO-TEQ kg−1 b.w.ResultsGenerally, levels in fish muscles were low in relation to maximum limits (4), being in the range of 0.02–3.98 pg WHO-TEQ g−1 wet weight (w.w.) for PCDD/F/DL-PCBs and 0.05–24.94 ng g−1 w.w. for NDL-PCBs. The highest concentration was found in eel muscles. The least polluted were pangas and zanders and the levels were at the limits of quantification. Consumption of two portions of fish per week results in intakes of 9– 866% TWI by children and 4–286% TWI by adults.ConclusionFrequent consumption of some species (for example eel and bream) can pose a health risk to vulnerable consumers and especially children and pregnant women.
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Kawashima, Ayato, Misato Katayama, Noriko Matsumoto, and Katsuhisa Honda. "Physicochemical characteristics of carbonaceous adsorbent for dioxin-like polychlorinated biphenyl adsorption." Chemosphere 83, no. 6 (April 2011): 823–30. http://dx.doi.org/10.1016/j.chemosphere.2011.02.074.

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Demond, Avery, Timothy Towey, Peter Adriaens, Xiaobo Zhong, Kristine Knutson, Qixuan Chen, Biling Hong, et al. "Relationship between polychlorinated dibenzo-p-dioxin, polychlorinated dibenzofuran, and dioxin-like polychlorinated biphenyl concentrations in vegetation and soil on residential properties." Environmental Toxicology and Chemistry 29, no. 12 (October 20, 2010): 2660–68. http://dx.doi.org/10.1002/etc.344.

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Reindl, Andrzej R., and Lucyna Falkowska. "Food source as a factor determining birds' exposure to hazardous organic pollutants and egg contamination." Marine and Freshwater Research 71, no. 4 (2020): 557. http://dx.doi.org/10.1071/mf19159.

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Alimentary exposure is the main factor determining halogenated organic compound pollution of wildlife, with birds’ eggs recognised as bioindicators of these contaminants and often used as a non-invasive monitoring tool. Comparisons of bird species from two aquatic environments, namely a marine coastal area (Gdansk Bay) and an inland reservoir (Włocławek Dam on the Vistula River), indicated significant differences in egg contamination. Herring gull eggs from Włocławek Dam had high concentrations of highly chlorinated dioxin (i.e. octachlorodibenzodioxin, which accounted for 37% of all polychlorinated dibenzo-p-dioxins and polychlorinated dibenzo furans, PCDD/Fs). In contrast, eggs from terns feeding along the coastal area of the Southern Baltic contained high concentrations of lowly chlorinated furans (i.e. pentachlorodibezofuran, which accounted for 46 and 45% of all PCDD/Fs in eggs from the sandwich tern and common tern respectively). The congener patterns in terns’ eggs were similar to those reported previously for Baltic fish. Polychlorinated biphenyl congener 180 had the highest concentrations among the mono-ortho chlorinated biphenyls, whereas concentrations of non-dioxin-like chlorinated biphenyls were 10-fold higher than those of the other congeners analysed, but the congener pattern in eggs from both species (sandwich and common tern) was similar to that reported in other studies. Among the hexabromocyclododecane (HBCD) isomers, α-HBCD dominated in all eggs analysed (accounting for >97% of all HBCDs). The total HBCD concentration in gulls’ eggs from the inland reservoir was approximately half that in eggs from the common and sandwich terns (mean±s.d. 47.33±33.22v. 97.98±59.69 and 104.00±63.66ngg–1 lipid weight respectively).
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Kawashima, Ayato, Hideno Akihiro, Hidetaka Morita, Masayoshi Fukuoka, Katsuhisa Honda, and Masatoshi Morita. "Dioxin-like polychlorinated biphenyl adsorbent obtained from enzymatic saccharification residue of lignocellulose." Bioresource Technology 102, no. 7 (April 2011): 4682–87. http://dx.doi.org/10.1016/j.biortech.2011.01.033.

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Lee, Ching-Chang, Hsin-Tang Lin, Ya-Min Kao, Mei-Hua Chang, and Hsiu-Ling Chen. "Temporal trend of polychlorinated dibenzo-p-dioxin/polychlorinated dibenzofuran and dioxin like-polychlorinated biphenyl concentrations in food from Taiwan markets during 2004–2012." Journal of Food and Drug Analysis 24, no. 3 (July 2016): 644–52. http://dx.doi.org/10.1016/j.jfda.2016.02.006.

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Brankovič, Jana, Gregor Fazarinc, Maja Antanasova, Peter Jevnikar, Janja Jan, Ines Anders, Katarina Pavšič Vrtač, Breda Jakovac Strajn, David Antolinc, and Milka Vrecl. "Lactational exposure to dioxin-like polychlorinated biphenyl 169 and nondioxin-like polychlorinated biphenyl 155: Effects on rat femur growth, biomechanics and mineral composition." Ecotoxicology and Environmental Safety 180 (September 2019): 106–13. http://dx.doi.org/10.1016/j.ecoenv.2019.04.076.

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Holland, E. B., and I. N. Pessah. "Non-dioxin-like polychlorinated biphenyl neurotoxic equivalents found in environmental and human samples." Regulatory Toxicology and Pharmacology 120 (March 2021): 104842. http://dx.doi.org/10.1016/j.yrtph.2020.104842.

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Більше джерел

Дисертації з теми "Dioxin-like Polychlorinated Biphenyl"

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Liberatori, Giulia. "Environmental risk assessment approach based on ecotoxicological tools applied in industrialized and agricultural areas." Doctoral thesis, Università di Siena, 2021. http://hdl.handle.net/11365/1131804.

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Environmental pollution is one of the most serious problems facing humanity and other life forms on our planet today. The characterization of chemicals spread in the environment, through the standard procedure of Environmental Risks Assessment (ERA) still evaluates the risk substance-by-substance. However, it is known that in the environment we are exposed to a mixture of chemicals coming from several different sources. In order to overcome such limitations of current ERA approach, more recently ERA highly recommended the usage of bioanalytical tools which is still emerging and not established in each European Member State. Within this thesis the suitability of bioanalytical tools in the ERA of industrial and agricultural areas, where mixtures of contaminants are present, has been demonstrated. In particular, the suitability of the in vitro cellular bioassay DR CALUX® (Dioxin Responsive, Chemically Activated LUciferase gene eXpression) has been evaluated. DR CALUX® were able to detect the biological toxicity of topsoils collected from Taranto municipality (Apulia Region). Through a combined approach of bioassay and chemical analysis, the occurrence and spatial distribution of polyhalogenated dioxins, furans and dl-PCBs in topsoil samples were assessed. This approach not only confirmed already known sources (e.g. industrial air emissions) but also new ones (e.g. illegal disposal of electric transformers containing Apirolio® and asbestos cement-fiber plates). Considering the extension of illegal landfills in the Taranto municipality area, it is an urgent need to investigate potential sources and impact of dioxin-like compounds. Here we evaluated the suitability of DR CALUX® to support their application in future monitoring surveys. The risk represented by the extensive use of soils for agricultural and food purposes in Taranto area, further underlines the need to apply monitoring tools that quickly and extensively highlight the hazard posed by dioxin-like compounds in terms of human and environmental health. The high costs associated to extensive monitoring surveys find in the application of bioassays a successful alternative, able to identify new and unexpected sources and their route of exposure that would require long times and huge investments if only based on analytical chemical analysis. The possibility to couple proteomics to the DR CALUX® cells bioassay was also investigated in the present thesis. A case study was thus designed and tested by using selected topsoil samples to extrapolate differentially abundant proteins by proteomics and thus monitor other chemicals including those of emerging concerns (CECs) present in the soil sample able to activate specific cellular pathways. Moreover, differently abundant proteins spots found will subjected to functional and pathway analysis, in order to highlight potentially altered molecular pathways and suggesting potential link to human pathologies. The differential proteins identified were related to an altered unfolded protein response (UPR) inducing Endoplasmic Reticulum (ER) stress, oxidative stress, and altered signal transduction, transforming growth factor beta (TGF-β) signaling alteration. All these mechanisms are reported to be related to carcinogenic mechanisms. The combined approach leads to estimate ecological and human risk by legacy and CECs as pharmaceuticals. The suitability of combining bioanalytical tools with chemical analyses in order to evaluate potential risks for both humans and environment, was demonstrated also in sewage sludge (SL) and hydrochar (HC) samples. A case study was designed to test urban SL and relative HC from six wastewater treatment plants (WWTPs), located in the Tuscany territory. DR CALUX® bioassay was able to detect the presence of dioxins and dioxin-like compounds in both SL and HC underlying differences probably related to hydrothermal carbonization process (HTC). Chemical analysis show that highly chlorinated congeners prevailed in SL compared to HC samples, in agreement with previous studies. HTC process seems responsible for such changes in the level of chlorinated congeners from high to low ones, which are more toxic. It can be assumed that the contamination of the HC is mainly due to a previous contamination of SL feedstock. The increase in the biological toxicity observed by DR CALUX® can be related to the de-chlorination of dioxins and dioxin-like compounds and the high loss of water which might affect their levels. DR CALUX® bioassay was able to screen the presence of dioxins and dioxin-like compounds in SL and HC, raising concern due to their possible applications as soil amendments. In the light of the above findings, it is possible to state that the DR CALUX® bioassay has been proven to be an effective and sensitive tool able to screen the presence of dioxins and dioxin-like compounds in various environmental matrices such as topsoil, sludge and hydrochar. Moreover, it has been proven to be an integrated state-of-the-art tool capable of assessing the real toxicity of complex mixtures of contaminants that occur in environmental samples. The combined application of DR CALUX® bioassay with chemical analysis and proteomics, opens new paths to the future of the Environmental Risk Assessment.
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Lundgren, Kjell. "Properties and analysis of dioxin-like compounds in marine samples from Sweden." Doctoral thesis, Umeå universitet, Kemiska institutionen, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-24.

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Polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (PCBs) have been assigned toxic equivalency factors (TEFs). These compounds are today routinely analysed with sophisticated analytical techniques. In a near future, there might be other dioxinlike compounds such as polychlorinated naphthalenes (PCNs), alkyl-polychlorodibenzofurans (R-PCDFs), and polychlorinated dibenzothiophenes (PCDTs) added to this list of toxic dioxin-like compounds. It is therefore important to have a readiness to analyse these new compounds in environmental samples. In this study, a multi-residue non-destructive analytical method for the analyses of these planar dioxin-like compound classes was developed. The use of HPLC PX-21 carbon column fractionation enabled the separation of interfering PCBs from coplanar PCBs and other planar dioxin-like compounds of interest. The obtained planar fraction containing the dioxin-like compounds was analysed using high-resolution GC-MS. Levels of PCNs in surface sediments and settling particulate matter in the northern Baltic Sea were determined. The concentrations of PCNs in background surface sediments were approximately 1 ng/g dw and the estimated PCN fluxes were similar to the pre-industrial levels determined in Europe. The PCN congener patterns in the surface sediments suggest that the PCNs deposited in the Baltic Sea originate from similar sources. Bioaccumulation of PCNs in a benthic food chain (sediment, amphipod, isopod, and four-horned sculpin) from the Gulf of Bothnia was studied. The results indicated that only a few PCN congeners biomagnified. The highest biomagnification factors (BMFs) were found for 2,3,6,7-substituted congeners and those lacking adjacent hydrogen-substituted carbon atoms. The calculated biota to sediment accumulation factors (BSAFs) showed that the tetra- and penta- CNs exhibited BSAF values higher than one, while BSAFs for the more chlorinated PCNs were less than one. A general difference between the northern and southern parts of the Gulf of Bothnia could be seen in the samples, with the lowest PCN and total PCB concentrations being found in the north and the highest in the south. This gradient is related to distance from the more industrialised and populated regions in the southern parts of Sweden and Finland, and central Europe. Analysis of R-PCDFs in crustacean samples from the Swedish west coast was performed using HRGC-MS/MS. The ΣR-PCDFs in these samples were present at concentrations up to 10 times higher than the ΣPCDFs. The relatively high concentrations of R-PCDFs in the crab samples demonstrate that these compounds bioaccumulate. The fate of a pollutant in the environment and the toxicity of a compound are governed by its physicochemical properties. The information found in a data set of properties can predict a compound’s mode of action. The following physicochemical properties for 87 PCDFs were measured: ultra-violetadsorption, relative retention times on two common gas chromatographic stationary phases, and relative mass spectrometric response factors using EI- and NCI- modes.
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Nieuwoudt, Claudine. "The determination of dioxin-like POPs in sediments and fish of the Vaal Triangle region, Gauteng, South Africa / Claudine Nieuwoudt." Thesis, North-West University, 2006. http://hdl.handle.net/10394/1619.

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Öberg, Mattias U. L. "Health risk assessment of dioxin-like compounds in complex samples /." Stockholm : Karolinska inst, 2003. http://diss.kib.ki.se/2003/91-7349-692-8.

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Ardzivian, Elnar Arpiné [Verfasser], and Alexandra K. [Akademischer Betreuer] Kiemer. "Short and long term neurotoxic effects following lactational exposure to the sum of the six non-dioxin-like polychlorinated biphenyls (∑6 NDL-PCBs) at low levels in offspring mice / Arpiné Ardzivian Elnar. Betreuer: Alexandra K. Kiemer." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2013. http://d-nb.info/1052781217/34.

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Hu, Shu-Chuan, and 胡淑娟. "A Survey Study on the Concentrations of Polychlorinated Dibenzo-p-dioxins, Dibenzofurans, and Dioxin-like polychlorinated Biphenyls in the Baby Formulas in Taiwan." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/8mqvqv.

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碩士
國立成功大學
環境醫學研究所
90
Polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) are important persistent organic pollutants. They were reported to cause reproductive and developmental effects in human and the infant is more vulnerable than the adult. Over 90% of human exposure to PCDD/PCDF/PCBs is due to food consumption. In Taiwan, less than 30% of mothers breast-feed their babies. For those infants without breast-feeding, the baby formula is their major exposure source. The objectives of this study are to measure the concentrations of 7 PCDD, 10 PCDF, and 12 dioxin-like PCB congeners in the major baby formulas consumed in Taiwan and to assess the first 6-month exposure of PCDD/PCDF/PCBs from baby formulas consumption for infants. The list of top-ten baby formula products was obtained by questionnaires answered by nursing mothers. The 17 PCDD/PCDF and 12 dioxin-like PCB congeners are analyzed according to the US EPA Method 1613B and 1668A, respectively, using high-resolution gas chromatography with high-resolution mass spectrometry. The mean toxic equivalent concentrations of PCDD/PCDFs and dioxin-like PCBs for these baby formula products were 0.73(±0.18) and 0.33(±0.05) pg WHO98-TEQ/g-lipid, respectively. The first 6-month exposure to PCDD/PCDFs and dioxin-like PCBs for infants via formula consumption are 19 and 9 pg WHO98-TEQ/day, respectively. These are equal to 2.5 and 1.5 pg WHO98-TEQ/kg/day, respectively. The accumulated intake of PCDD/PCDFs and dioxin-like PCBs in the 6-month period are 3.3 and 1.6 ng WHO98-TEQ, respectively.
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Santoro, Anna. "LEVELS OF POLYCHLORINATED BIPHENYLS (PCBs) AND ORGANOCHLORINE PESTICIDES (OCPs) IN BIOINDICATOR SPECIES AND EVALUATION OF TOXIC EFFECTS OF NON-DIOXIN LIKE PCBs 101, 153 AND 180 ON IMMUNE AND ENDOCRINE SYSTEMS." Tesi di dottorato, 2014. http://www.fedoa.unina.it/9831/1/tesi%20dottorato%20anna%20santoro.pdf.

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During my PhD course, the residue levels of Polychlorinated biphenyls (PCBs) and Organochlorine pesticides (OCPs) in the edible tissues of two bivalve species (Mytilus galloprovincialis and Ensis siliqua) from Tyrrhenian Sea (Mediterranean Sea) were measured. Factors explaining differences in bioaccumulation levels were also considered and an evaluation of the health risk for human consumer was provided. A gas chromatography–electron capture detection (GC-ECD) was used for the analysis; the concentration levels of five OCPs—among which the 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)-ethane (p,p’-DDT)—and twenty PCBs, including the seven indicator-PCBs, were determined. Differences in residue levels were revealed between the two examined species; in some cases they were statistically significant. PCBs were the most abundant pollutants (mean values of 422.19 ng g-1 and 399.33 ng g-1, respectively, for mussels and clams on fat weight), followed by DDTs, Dieldrin and hexachlorobenzene (HCB). In particular, the PCBs nos. 101, 118, 138 and 153 were the dominant congeners, accounting for 66% and 56% of the total residue levels of PCBs in mussels and clams, respectively. From the human health point of view, OCPs residue levels were below the national limits established for fish and aquatic products. Conversely, the mean concentrations of PCBs exceeded the limits set by the EU for terrestrial foods in both species. Non-dioxin-like (NDL)-PCBs are stable and lipophilic chemicals that persist in the environment and tend to bioaccumulate in the food chain. Epidemiological studies show that PCB exposure is associated with modifications of innate and adaptive immunity, including effects on immune cells and signalling molecules involved in the response against foreign antigens. It is noteworthy that no in vitro studies are available regarding the impairment of immune innate response due to NDL-PCB exposure. Therefore, here we investigated the effects of NDL-PCBs 101, 153, and 180, alone or differently associated, on lipopolysaccharide (LPS)-activated J774A.1 murine macrophages. Interestingly, concentrations of the aforesaid NDL-PCBs inactive by themselves induced immunesoppression when NDL-PCBs were differently combined. In particular, the exposure to NDL-PCB mixture caused a significative suppression of LPS-induced cytokine synthesis, as well as nitrite (NO-2) production and proinflammatory enzyme expression. The involvement and role of nuclear factor-kB (NF-kB) in the effects of these pollutants was also demonstrated. Western blot analysis of NF-kB showed that LPS-induced NF-kB activation was significantly decreased by the exposure of macrophages to NDL-PCB associations. These results demonstrated the impaired capability of macrophages to respond properly to noxious stimuli, such as LPS, mimicking the environmental co-exposure to these compounds. In conclusion, our findings suggest that, although less toxic than dioxin like (DL) congeners, the NDL-PCBs tested are equally dangerous as well as immunotoxic pollutants, also considering their presence as mixtures and at higher levels than DL-PCBs in biotic and abiotic matrices. Interestingly, NDL PCBs tend to accumulate in adipose tissue. Therefore, we evaluated the alteration of the mature 3T3-L1 adipocyte metabolism induced by PCB 101, 153 and 180 alone or associated two by two or all together. We observed an increase in lipid content and leptin gene expression and a concomitant reduction of hormone receptor expression and activity. These modifications support the induction of leptin-resistance, a typical metabolic complication of obesity. Consequently, we investigated how these PCBs affect the expression of important proteins involved in the signalling of leptin receptor. In particular, the phosphatase PTP1B and the suppressor of cytokine signalling (SOCS) 3, two negative regulators of leptin signalling, were induced by the association of the PCB 153 with the 180 or of all PCBs. Conversely, the same associations caused a significant decrease in the phosphorylation of STAT3, a downstream activator of the transcription of leptin gene targets. This effect has been also associated to the inactivation of AMPK/ACC pathway through the reduction of the phosphorylation of these enzymes, and hence the increase in lipid content. Furthermore, it was highlighted the ability of these pollutants to increase the transcription of inflammatory cytokines, such as IL-6 and TNF alpha. Interestingly, it is important to highlight that PCB concentrations used in this study are comparable to levels detectable in human adipose tissue. Our data strongly support the hypothesis that these substances may interfere with the lipid metabolism contributing to the development of obesity and related diseases. Obesity is a clear risk factor for Osteoarthitis (OA). Adipokines are factors, dysregulated in obesity and that play an increasing pathogenic role in OA. Apoptosis is involved in extracellular matrix (ECM) degradation, thus the identification of inductors of this process is important for the understanding pathogenesis/progression of OA. We also evaluated the adverse effect of PCBs 101, 153 and 180 on human and murine chondrocytes by assessing apoptosis pathways. Murine chondrogenic ATDC5 cell line and human T/C-28a2 immortalized chondrocytes were exposed to NDL-PCBs 101, 153 and 180. Cell viability was examined using MTT assay. Necrosis was evaluated by LDH assay and Annexin V flow cytometric assay. Expression of apoptotic related proteins, such as caspase 3, Bcl-2 and Bax, was assessed by Western blot analysis. Oxidative stress was evaluated by malondialdehyde (MDA) assay and the Oxidative Stress Index (OSI). Exposure to examined PCBs caused the loss of cell viability and accelerated apoptosis in a concentration-dependent manner both in murine and human chondrocytes. Data from Annexin V and LDH assays showed necrosis induction. Caspase 3 activation, as well as, altered Bcl-2/Bax ratio and p38 phosphorylation suggested apoptosis induction. Finally, MDA levels and OSI revealed that PCBs drive chondrocytes towards oxidative stress. Our results indicate that the activity of PCBs on cell viability is likely to be mediated by alterations in the mechanisms of regulation of apoptosis and necrosis. Overall, these data highlight a novel role of environmental pollutants in the pathophysiology of chondrocytes.
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Книги з теми "Dioxin-like Polychlorinated Biphenyl"

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H, Smith Allan. Evaluation of the toxicity of dioxins nd dioxin-like PCBs: A health risk appraisal for the Nw Zealand population. Wellington, N.Z: Ministry for the Environment = Manatu Mo Te Taiao, 2001.

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Частини книг з теми "Dioxin-like Polychlorinated Biphenyl"

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Koss, Günter, and Detlef Wölfle. "Dioxin and Dioxin-like Polychlorinated Hydrocarbons and Biphenyls." In Toxicology, 699–728. Elsevier, 1999. http://dx.doi.org/10.1016/b978-012473270-4/50088-2.

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2

Rose, Martin. "Dioxins, Furans, and Dioxin-Like Polychlorinated Biphenyls (Update)." In Reference Module in Food Science. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-12-822521-9.00081-2.

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Rose, M. "Environmental Contaminants: Dioxins, Furans, and Dioxin-like Polychlorinated Biphenyls." In Encyclopedia of Food Safety, 315–22. Elsevier, 2014. http://dx.doi.org/10.1016/b978-0-12-378612-8.00197-9.

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Olanca, Burcu. "Polychlorinated Dibenzo-p-Dioxins, Polychlorinated Dibenzofurans, and Dioxin-Like Polychlorinated Biphenyls in Chicken Eggs." In Egg Innovations and Strategies for Improvements, 485–98. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-800879-9.00046-9.

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Elabbas, L. E., E. Westerholm, R. Roos, K. Halldin, M. Korkalainen, M. Viluksela, and H. Håkansson. "Non-dioxin-like polychlorinated biphenyls (NDL-PCBs) in foods: exposure and health hazards." In Persistent Organic Pollutants and Toxic Metals in Foods, 215–60. Elsevier, 2013. http://dx.doi.org/10.1533/9780857098917.2.215.

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"Hudson River Fishes and their Environment." In Hudson River Fishes and their Environment, edited by Isaac Wirgin and R. Christopher Chambers. American Fisheries Society, 2006. http://dx.doi.org/10.47886/9781888569827.ch19.

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Анотація:
<em>Abstract.</em>—Despite recent successes in eliminating or reducing many point sources of chemical contaminants, sediments in the Hudson River Estuary are still highly contaminated with lipophilic and highly persistent polychlorinated biphenyls (PCBs), polychlorinated dibenzo-<em>p</em>-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polycyclic aromatic hydrocarbons (PAHs). These have been shown to bioaccumulate to high levels in resource species and other key ecological components of the Hudson River food web. Resource managers and stewards must consider the possible toxic effects of these pollutants on the Hudson River biota, including its fish community; however, few studies have directly investigated these effects. A series of toxicological studies on Atlantic tomcod <em>Microgadus tomcod </em>from the Hudson River Estuary have demonstrated profound and broad-based changes in response to local contaminants. Levels of contaminants in the tissues of different life stages of tomcod from the Hudson River Estuary far exceed those in tomcod from other Atlantic Coast estuaries. More importantly, a combination of field and laboratory studies has demonstrated molecular to population level perturbations in tomcod from the Hudson River, all of which are consistent with chemical exposures and many of which appear to be mechanistically linked. These effects include induction of hepatic expression of cytochrome P4501A1 mRNA, high levels of hepatic DNA damage, somatic mutations at an oncogene locus critical to the initiation of chemical carcinogenesis, elevated prevalence of gross and histologically defined hepatic tumors, truncated age structure, and dramatic resistance at the molecular and organismal levels to halogenated aromatic hydrocarbons (HAHs). Resistance, a population level effect, was observed in the toxic responses of tomcod embryos and larvae to 2,3,7,8-tetrachlorodibenzo-<em>p</em>-dioxin (TCDD) and TCDD-like PCBs, but not PAHs. Because young of the year tomcod are a critical node in the Hudson River food chain, their evolved resistance to HAHs and high body burden of these and related contaminants has likely resulted in the trophic transfer of these contaminants to secondary and tertiary consumers of the Hudson River, including important resource species, and an elevated tissue burden of these contaminants in those consumers. In total, these studies are consistent with the hypothesis that exposure to Hudson River-borne contaminants has significantly altered its tomcod population and perhaps evoked broad change in the Hudson River fish community.
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7

"Hudson River Fishes and their Environment." In Hudson River Fishes and their Environment, edited by Isaac Wirgin and R. Christopher Chambers. American Fisheries Society, 2006. http://dx.doi.org/10.47886/9781888569827.ch19.

Повний текст джерела
Анотація:
<em>Abstract.</em>—Despite recent successes in eliminating or reducing many point sources of chemical contaminants, sediments in the Hudson River Estuary are still highly contaminated with lipophilic and highly persistent polychlorinated biphenyls (PCBs), polychlorinated dibenzo-<em>p</em>-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polycyclic aromatic hydrocarbons (PAHs). These have been shown to bioaccumulate to high levels in resource species and other key ecological components of the Hudson River food web. Resource managers and stewards must consider the possible toxic effects of these pollutants on the Hudson River biota, including its fish community; however, few studies have directly investigated these effects. A series of toxicological studies on Atlantic tomcod <em>Microgadus tomcod </em>from the Hudson River Estuary have demonstrated profound and broad-based changes in response to local contaminants. Levels of contaminants in the tissues of different life stages of tomcod from the Hudson River Estuary far exceed those in tomcod from other Atlantic Coast estuaries. More importantly, a combination of field and laboratory studies has demonstrated molecular to population level perturbations in tomcod from the Hudson River, all of which are consistent with chemical exposures and many of which appear to be mechanistically linked. These effects include induction of hepatic expression of cytochrome P4501A1 mRNA, high levels of hepatic DNA damage, somatic mutations at an oncogene locus critical to the initiation of chemical carcinogenesis, elevated prevalence of gross and histologically defined hepatic tumors, truncated age structure, and dramatic resistance at the molecular and organismal levels to halogenated aromatic hydrocarbons (HAHs). Resistance, a population level effect, was observed in the toxic responses of tomcod embryos and larvae to 2,3,7,8-tetrachlorodibenzo-<em>p</em>-dioxin (TCDD) and TCDD-like PCBs, but not PAHs. Because young of the year tomcod are a critical node in the Hudson River food chain, their evolved resistance to HAHs and high body burden of these and related contaminants has likely resulted in the trophic transfer of these contaminants to secondary and tertiary consumers of the Hudson River, including important resource species, and an elevated tissue burden of these contaminants in those consumers. In total, these studies are consistent with the hypothesis that exposure to Hudson River-borne contaminants has significantly altered its tomcod population and perhaps evoked broad change in the Hudson River fish community.
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8

Ylitalo, Gina, Jon Buzitis, Daryle Boyd, David Herman, Karen Tilbury, and Margaret Krahn. "Improvements to high-performance liquid chromatography/photodiode array detection (HPLC/PDA) method that measures dioxin-like polychlorinated biphenyls and other selected organochlorines in marine biota." In Techniques in Aquatic Toxicology, Volume 2. CRC Press, 2005. http://dx.doi.org/10.1201/9780203501597.ch25.

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Тези доповідей конференцій з теми "Dioxin-like Polychlorinated Biphenyl"

1

Stancheva, Mona, Mona Stancheva, Stanislava Georgieva, Stanislava Georgieva, Zlatina Peteva, Zlatina Peteva, Lubomir Makedonski, and Lubomir Makedonski. "POLYCHLORINATED BIPHENYLS IN EDIBLE FISH FROM BLACK SEA, BULGARIA." In Managing risks to coastal regions and communities in a changing world. Academus Publishing, 2017. http://dx.doi.org/10.31519/conferencearticle_5b1b93b39d6a08.20094934.

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Анотація:
Polychlorinated biphenyls (PCBs) can still be a problem for the aquatic environment. Fish species are a suitable indicator for the environmental pollution monitoring because they concentrate pollutants in their tissues directly from water. Concentrations of PCBs were measured in marine fish, collected from Bulgarian Black Sea coast in order to monitor the dynamics of these pollutants in 2007, 2010 and 2015. The fish species: goby (Neogobius melanostomus), sprat (Sprattus sprattus sulinus), horse mackerel (Trachurus Mediterraneus ponticus) and grey mullet (Mugil cephalus) were chosen because of their characteristic feeding behavior. The PCBs were determined by gas chromatography system with mass spectrometry detection. The Total PCBs ranged from 93.8 to 513.3 ng/g lipid weight (in grey mullet and goby, respectively). Levels of PCBs in goby and grey mullet decreased in 2010 and 2015. In order to assess the safety of fish as food were calculated TEQ. They are determined by the results of dioxin - like (dl) PCBs. TEQs were calculated from 0.01 to 0.04 pg TEQ/g ww and did not exceed the EC limit of 3 pg TEQ/g ww. The levels of PCBs in fish from Bulgarian Black Sea were comparable to those found in neighboring seas.
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2

Stancheva, Mona, Mona Stancheva, Stanislava Georgieva, Stanislava Georgieva, Zlatina Peteva, Zlatina Peteva, Lubomir Makedonski, and Lubomir Makedonski. "POLYCHLORINATED BIPHENYLS IN EDIBLE FISH FROM BLACK SEA, BULGARIA." In Managing risks to coastal regions and communities in a changing world. Academus Publishing, 2017. http://dx.doi.org/10.21610/conferencearticle_58b4315bdce00.

Повний текст джерела
Анотація:
Polychlorinated biphenyls (PCBs) can still be a problem for the aquatic environment. Fish species are a suitable indicator for the environmental pollution monitoring because they concentrate pollutants in their tissues directly from water. Concentrations of PCBs were measured in marine fish, collected from Bulgarian Black Sea coast in order to monitor the dynamics of these pollutants in 2007, 2010 and 2015. The fish species: goby (Neogobius melanostomus), sprat (Sprattus sprattus sulinus), horse mackerel (Trachurus Mediterraneus ponticus) and grey mullet (Mugil cephalus) were chosen because of their characteristic feeding behavior. The PCBs were determined by gas chromatography system with mass spectrometry detection. The Total PCBs ranged from 93.8 to 513.3 ng/g lipid weight (in grey mullet and goby, respectively). Levels of PCBs in goby and grey mullet decreased in 2010 and 2015. In order to assess the safety of fish as food were calculated TEQ. They are determined by the results of dioxin - like (dl) PCBs. TEQs were calculated from 0.01 to 0.04 pg TEQ/g ww and did not exceed the EC limit of 3 pg TEQ/g ww. The levels of PCBs in fish from Bulgarian Black Sea were comparable to those found in neighboring seas.
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