Статті в журналах з теми "Dihydroxypyrimidines"
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Powdrill, Megan H., Jerome Deval, Frank Narjes, Raffaele De Francesco, and Matthias Götte. "Mechanism of Hepatitis C Virus RNA Polymerase Inhibition with Dihydroxypyrimidines." Antimicrobial Agents and Chemotherapy 54, no. 3 (December 22, 2009): 977–83. http://dx.doi.org/10.1128/aac.01216-09.
Повний текст джерелаGuo, Di-Liang, Xing-Jie Zhang, Rui-Rui Wang, Yu Zhou, Zeng Li, Jin-Yi Xu, Kai-Xian Chen, Yong-Tang Zheng, and Hong Liu. "Structural modifications of 5,6-dihydroxypyrimidines with anti-HIV activity." Bioorganic & Medicinal Chemistry Letters 22, no. 23 (December 2012): 7114–18. http://dx.doi.org/10.1016/j.bmcl.2012.09.070.
Повний текст джерелаNovais, H. M., and S. Steenken. "Reactions of oxidizing radicals with 4,6-dihydroxypyrimidines as model compounds for uracil, thymine, and cytosine." Journal of Physical Chemistry 91, no. 2 (January 1987): 426–33. http://dx.doi.org/10.1021/j100286a034.
Повний текст джерелаTelvekar, Vikas N., and Kavitkumar N. Patel. "Pharmacophore Development and Docking Studies of the HIV-1 Integrase Inhibitors Derived from N-methylpyrimidones, Dihydroxypyrimidines, and Bicyclic Pyrimidinones." Chemical Biology & Drug Design 78, no. 1 (May 25, 2011): 150–60. http://dx.doi.org/10.1111/j.1747-0285.2011.01130.x.
Повний текст джерелаAstrat'ev, A. A., D. V. Dashko, A. Yu Mershin, A. I. Stepanov, and N. A. Urazgil'deev. "ChemInform Abstract: Some Specific Features of Acid Nitration of 2-Substituted 4,6-Dihydroxypyrimidines. Nucleophilic Cleavage of the Nitration Products." ChemInform 32, no. 51 (May 23, 2010): no. http://dx.doi.org/10.1002/chin.200151070.
Повний текст джерелаWinterbourn, Christine C., and Rex Munday. "Concerted Action Of Reduced Glutathione And Superoxide Dismutase In Preventing Redox Cycling Of Dihydroxypyrimidines, And Their Role In Antioxidant Defence." Free Radical Research Communications 8, no. 4-6 (January 1990): 287–93. http://dx.doi.org/10.3109/10715769009053361.
Повний текст джерелаJansa, Petr, Antonín Holý, Martin Dračínský, Viktor Kolman, Zlatko Janeba, Petra Kostecká, Eva Kmoníčková, and Zdeněk Zídek. "5-Substituted 2-amino-4,6-dihydroxypyrimidines and 2-amino-4,6-dichloropyrimidines: synthesis and inhibitory effects on immune-activated nitric oxide production." Medicinal Chemistry Research 23, no. 10 (May 9, 2014): 4482–90. http://dx.doi.org/10.1007/s00044-014-1018-9.
Повний текст джерелаShi, Daqing, Lihui Niu, and Qiya Zhuang. "Clean synthesis of pyrido[2,3-d]pyrimidines in aqueous media." Journal of Chemical Research 2005, no. 10 (October 2005): 648–50. http://dx.doi.org/10.3184/030823405774663048.
Повний текст джерелаKufelnicki, Aleksander, Jan Jaszczak, Urszula Kalinowska-Lis, Cecylia Wardak, and Justyn Ochocki. "Complexes of Uracil (2,4-Dihydroxypyrimidine) Derivatives." Journal of Solution Chemistry 35, no. 5 (May 2006): 739–51. http://dx.doi.org/10.1007/s10953-006-9017-1.
Повний текст джерелаNovais, H. M., and S. Steenken. "ESR studies of electron and hydrogen adducts of thymine and uracil and their derivatives and of 4,6-dihydroxypyrimidines in aqueous solution. Comparison with data from solid state. The protonation at carbon of the electron adducts." Journal of the American Chemical Society 108, no. 1 (January 1986): 1–6. http://dx.doi.org/10.1021/ja00261a001.
Повний текст джерелаRostkowska, Hanna, Anna Luchowska, Leszek Lapinski, and Maciej J. Nowak. "Photochemical transformations of 4,6-dihydroxypyrimidine and 2-methyl-4,6-dihydroxypyrimidine isolated in low-temperature Ar, Ne and H2 matrices." Chemical Physics Letters 745 (April 2020): 137263. http://dx.doi.org/10.1016/j.cplett.2020.137263.
Повний текст джерелаKeerthi Kumar, Chinnagiri T., Jathi Keshavayya, Tantry N. Rajesh, Sanehalli K. Peethambar, and Angadi R. Shoukat Ali. "Synthesis, Characterization, and Biological Activity of 5-Phenyl-1,3,4-thiadiazole-2-amine Incorporated Azo Dye Derivatives." Organic Chemistry International 2013 (August 18, 2013): 1–7. http://dx.doi.org/10.1155/2013/370626.
Повний текст джерелаVu, Tuan Q., Nikolai V. Yudin, Alexander A. Kushtaev, Thanh X. Nguyen, and Sergey A. Maltsev. "Spectroscopic Study of the Basicity of 4,6-Dihydroxypyrimidine Derivatives." ACS Omega 6, no. 22 (May 24, 2021): 14154–63. http://dx.doi.org/10.1021/acsomega.1c00671.
Повний текст джерелаKapoor, Bharat, EzzedinA Luhishi, AndrewKK Chung, and JakobusC Pauw. "Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency." Indian Journal of Ophthalmology 56, no. 4 (2008): 336. http://dx.doi.org/10.4103/0301-4738.41422.
Повний текст джерелаMalancona, Savina, Mattia Mori, Paola Fezzardi, Marisabella Santoriello, Andreina Basta, Martina Nibbio, Lesia Kovalenko, et al. "5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein." ACS Medicinal Chemistry Letters 11, no. 5 (March 19, 2020): 766–72. http://dx.doi.org/10.1021/acsmedchemlett.9b00608.
Повний текст джерелаBoyd, Vincent A., John Mason, Parimala Hanumesh, Jeanine Price, Charles J. Russell, and Thomas R. Webb. "2-Substituted-4,5-Dihydroxypyrimidine-6-Carboxamide Antiviral Targeted Libraries." Journal of Combinatorial Chemistry 11, no. 6 (November 9, 2009): 1100–1104. http://dx.doi.org/10.1021/cc900111u.
Повний текст джерелаShennara, Khaled A., Ray J. Butcher та Frederick T. Greenaway. "Crystal structure of tetraaquabis(pyrimidin-1-ium-4,6-diolato-κO4)manganese(II)". Acta Crystallographica Section E Crystallographic Communications 73, № 4 (31 березня 2017): 620–22. http://dx.doi.org/10.1107/s2056989017004649.
Повний текст джерелаZhang, Xiao-Min, Hui-Liang Zhou, and Qi-Lin Hu. "N-(2-Amino-4,6-dihydroxypyrimidin-5-yl)acetamide dihydrate." Acta Crystallographica Section E Structure Reports Online 67, no. 9 (August 31, 2011): o2526. http://dx.doi.org/10.1107/s1600536811034441.
Повний текст джерелаMetwally, Mohamed Abbas, and Hassan Ali Etman. "The Synthesis of Indeno[l,2:4,5]pyrimido[l,2-a]benzimidazole-13-ones, Indeno[l,2-b]pyrazolo[4,3-e]pyridine-3,5-dione and Related Compounds*." Zeitschrift für Naturforschung B 41, no. 4 (April 1, 1986): 486–88. http://dx.doi.org/10.1515/znb-1986-0413.
Повний текст джерелаOtutu, O. J., and A. K. Asiagwu. "Synthesis and Application to Polyester and Nylon 6 Fabrics of Hetaryl Bis-Azo Disperse Dyes Based on 6-Amino-2,4-Dihydroxypyrimidine and 4-Methoxy-2-Nitroaniline Moieties." Journal of Scientific Research 11, no. 2 (May 1, 2019): 215–24. http://dx.doi.org/10.3329/jsr.v11i2.38734.
Повний текст джерелаTang, Jing, Kasthuraiah Maddali, Yves Pommier, Yuk Y. Sham, and Zhengqiang Wang. "Scaffold rearrangement of dihydroxypyrimidine inhibitors of HIV integrase: Docking model revisited." Bioorganic & Medicinal Chemistry Letters 20, no. 11 (June 2010): 3275–79. http://dx.doi.org/10.1016/j.bmcl.2010.04.048.
Повний текст джерелаPace, Paola, M. Emilia Di Francesco, Cristina Gardelli, Steven Harper, Ester Muraglia, Emanuela Nizi, Federica Orvieto, et al. "Dihydroxypyrimidine-4-carboxamides as Novel Potent and Selective HIV Integrase Inhibitors." Journal of Medicinal Chemistry 50, no. 9 (May 2007): 2225–39. http://dx.doi.org/10.1021/jm070027u.
Повний текст джерелаXu, Xue-Jiao, Peng Zheng, Gao-Ping Ren, Mei-Ling Liu, Jun Mu, Jing Guo, Du Cao, Zhao Liu, Hua-Qing Meng, and Peng Xie. "2,4-Dihydroxypyrimidine is a potential urinary metabolite biomarker for diagnosing bipolar disorder." Molecular BioSystems 10, no. 4 (2014): 813. http://dx.doi.org/10.1039/c3mb70614a.
Повний текст джерелаde Melo, Eduardo Borges, and Márcia Miguel Castro Ferreira. "Multivariate QSAR study of 4,5-dihydroxypyrimidine carboxamides as HIV-1 integrase inhibitors." European Journal of Medicinal Chemistry 44, no. 9 (September 2009): 3577–83. http://dx.doi.org/10.1016/j.ejmech.2009.03.001.
Повний текст джерелаOfitserova, E. S., A. A. Shklyarenko, I. P. Yakovlev, and E. V. Fedorova. "Vilsmeier–Haack formylation of ethyl [(4,6-dihydroxypyrimidin-2-yl)sulfanyl]acetate." Russian Journal of Organic Chemistry 52, no. 9 (September 2016): 1374–76. http://dx.doi.org/10.1134/s1070428016090256.
Повний текст джерелаBoyle, Timothy J., Mark A. Rodriguez, and Todd M. Alam. "4,6-Dihydroxypyrimidine: a selective bridging ligand for controlled Group IV metal alkoxide structures." Dalton Transactions, no. 24 (2003): 4598. http://dx.doi.org/10.1039/b310087a.
Повний текст джерелаPacini, Barbara, Salvatore Avolio, Caterina Ercolani, Uwe Koch, Giovanni Migliaccio, Frank Narjes, Laura Pacini, Licia Tomei, and Steven Harper. "2-(3-Thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acids as inhibitors of HCV NS5B RdRp." Bioorganic & Medicinal Chemistry Letters 19, no. 21 (November 2009): 6245–49. http://dx.doi.org/10.1016/j.bmcl.2009.06.106.
Повний текст джерелаMOSKVIN, A. V., N. M. PETROVA, E. A. SEMENOVA, M. SHOPOVA, V. A. GINDIN, and B. A. IVIN. "ChemInform Abstract: Azines and Azoles. Part 88. Condensation of 4,6-Dihydroxypyrimidine with Aromatic Aldehydes." ChemInform 25, no. 27 (August 19, 2010): no. http://dx.doi.org/10.1002/chin.199427164.
Повний текст джерелаKaren, Pavel, Richard L. Harlow, Zhigang Li, Paul Meenan, Patti A. Parziale, Kirsi Ranta, and Teófilo Rojo. "The Crystal Structure of 2-Amino-4,6-dihydroxypyrimidine Determined from Powder X-Ray Synchrotron Diffraction." Acta Chemica Scandinavica 52 (1998): 1051–55. http://dx.doi.org/10.3891/acta.chem.scand.52-1051.
Повний текст джерелаHe, Tianyu, Tiffany C. Edwards, Jiashu Xie, Hideki Aihara, Robert J. Geraghty, and Zhengqiang Wang. "4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease." Journal of Medicinal Chemistry 65, no. 7 (April 4, 2022): 5830–49. http://dx.doi.org/10.1021/acs.jmedchem.2c00203.
Повний текст джерелаYazdanbakhsh, M. R., H. Yousefi, M. Mamaghani, E. O. Moradi, M. Rassa, H. Pouramir, and M. Bagheri. "Synthesis, spectral characterization and antimicrobial activity of some new azo dyes derived from 4,6-dihydroxypyrimidine." Journal of Molecular Liquids 169 (May 2012): 21–26. http://dx.doi.org/10.1016/j.molliq.2012.03.003.
Повний текст джерелаPetrocchi, Alessia, Uwe Koch, Victor G. Matassa, Barbara Pacini, Kara A. Stillmock, and Vincenzo Summa. "From dihydroxypyrimidine carboxylic acids to carboxamide HIV-1 integrase inhibitors: SAR around the amide moiety." Bioorganic & Medicinal Chemistry Letters 17, no. 2 (January 2007): 350–53. http://dx.doi.org/10.1016/j.bmcl.2006.10.054.
Повний текст джерелаMuhammad, Munira Taj, Khalid Mohammed Khan, Arshia, Ajmal Khan, Fiza Arshad, Bibi Fatima, M. Iqbal Choudhary, Naima Syed, and Syed Tarique Moin. "Syntheses of 4,6-dihydroxypyrimidine diones, their urease inhibition, in vitro, in silico, and kinetic studies." Bioorganic Chemistry 75 (December 2017): 317–31. http://dx.doi.org/10.1016/j.bioorg.2017.08.018.
Повний текст джерелаWang, Kuan, Jian-Gang Chen, Bozhou Wang, Yueping Ji, Fengyi Liu, Zhao-Tie Liu, Wenliang Wang, Zhong-Wen Liu, Zhengping Hao, and Jian Lu. "Insight into the acidic group-induced nitration mechanism of 2-methyl-4,6-dihydroxypyrimidine (MDP) with nitronium." RSC Advances 6, no. 83 (2016): 80145–57. http://dx.doi.org/10.1039/c6ra18842g.
Повний текст джерелаKrishnakumar, V., and N. Prabavathi. "DFT simulations and vibrational analysis of FTIR and FT-Raman spectra of 2-amino-4,6-dihydroxypyrimidine." Journal of Raman Spectroscopy 39, no. 5 (February 13, 2008): 679–84. http://dx.doi.org/10.1002/jrs.1916.
Повний текст джерелаHoti, Ramiz, Hamit Ismaili, Veprim Thaçi, Gjyle Mulliqi-Osmani, Malësore Pllana-Zeqiri, and Agon Bytyqi. "An Efficient Synthesis of Novel 3-[(Heteroaryl-2-ylimino)-methyl]-4-hydroxy-chromen-2-ones and Analogue of Tetrazole Derivatives and Their Antibacterial Activity." Molbank 2021, no. 4 (December 2, 2021): M1303. http://dx.doi.org/10.3390/m1303.
Повний текст джерелаXiao, Bo, and et al. "Crystal structure of aqua-[(2,2’-bipyridine)]-[(2,4-dihydroxypyrimidine- 5-carboxylato)] perchloratocopper(II), Cu(H2O)(C10H8N2)(C5H3N2O4)(ClO4), C15H13ClCuN4O9." Zeitschrift für Kristallographie - New Crystal Structures 227, no. 3 (September 2012): 365–66. http://dx.doi.org/10.1524/ncrs.2012.0176.
Повний текст джерелаStansfield, Ian, Salvatore Avolio, Stefania Colarusso, Nadia Gennari, Frank Narjes, Barbara Pacini, Simona Ponzi, and Steven Harper. "Active site inhibitors of HCV NS5B polymerase. The development and pharmacophore of 2-thienyl-5,6-dihydroxypyrimidine-4-carboxylic acid." Bioorganic & Medicinal Chemistry Letters 14, no. 20 (October 2004): 5085–88. http://dx.doi.org/10.1016/j.bmcl.2004.07.075.
Повний текст джерелаSumma, Vincenzo, Alessia Petrocchi, Victor G. Matassa, Cristina Gardelli, Ester Muraglia, Michael Rowley, Odalys Gonzalez Paz, Ralph Laufer, Edith Monteagudo, and Paola Pace. "4,5-Dihydroxypyrimidine Carboxamides andN-Alkyl-5-hydroxypyrimidinone Carboxamides Are Potent, Selective HIV Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species." Journal of Medicinal Chemistry 49, no. 23 (November 2006): 6646–49. http://dx.doi.org/10.1021/jm060854f.
Повний текст джерелаLi, Xianghong, Shuduan Deng, Xiaoguang Xie, and Guanben Du. "Synergistic inhibition effect of 5-aminotetrazole and 4,6-dihydroxypyrimidine on the corrosion of cold rolled steel in H 3 PO 4 solution." Materials Chemistry and Physics 181 (September 2016): 33–46. http://dx.doi.org/10.1016/j.matchemphys.2016.06.031.
Повний текст джерелаSumma, Vincenzo, Alessia Petrocchi, Victor G. Matassa, Marina Taliani, Ralph Laufer, Raffaele De Francesco, Sergio Altamura та Paola Pace. "HCV NS5b RNA-Dependent RNA Polymerase Inhibitors: From α,γ-Diketoacids to 4,5-Dihydroxypyrimidine- or 3-Methyl-5- hydroxypyrimidinonecarboxylic Acids. Design and Synthesis". Journal of Medicinal Chemistry 47, № 22 (жовтень 2004): 5336–39. http://dx.doi.org/10.1021/jm0494669.
Повний текст джерелаCushman, Mark, Jeffrey T. Mihalic, Klaus Kis, and Adelbert Bacher. "Design and synthesis of 6-(6-D-ribitylamino-2,4-dihydroxypyrimidin-5-yl)-1-hexylphosphonic acid, a potent inhibitor of lumazine synthase." Bioorganic & Medicinal Chemistry Letters 9, no. 1 (January 1999): 39–42. http://dx.doi.org/10.1016/s0960-894x(98)00687-8.
Повний текст джерелаLi, Xin-yang, Jing-wei Liang, Kamara Mohamed O, Ting-jian Zhang, Guo-Qing Lu, and Fan-hao Meng. "Design, synthesis and biological evaluation of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido)benzoyl hydrazide derivatives as thymidylate synthase (TS) inhibitors and as potential antitumor drugs." European Journal of Medicinal Chemistry 154 (June 2018): 267–79. http://dx.doi.org/10.1016/j.ejmech.2018.05.020.
Повний текст джерелаCushman, Mark, Jeffrey T. Mihalic, Klaus Kis, and Adelbert Bacher. "ChemInform Abstract: Design and Synthesis of 6-(6-D-Ribitylamino-2,4-dihydroxypyrimidin-5-yl)-1-hexylphosphonic Acid, a Potent Inhibitor of Lumazine Synthase." ChemInform 30, no. 19 (June 16, 2010): no. http://dx.doi.org/10.1002/chin.199919169.
Повний текст джерелаKobayashi, Satoshi, Makoto Ueno, Gakuto Ogawa, Akira Fukutomi, Masafumi Ikeda, Takuji Okusaka, Tosiya Sato, et al. "Impact of renal function on the efficacy and safety of S-1 with concurrent radiotherapy for locally advanced pancreatic cancer." Journal of Clinical Oncology 37, no. 4_suppl (February 1, 2019): 301. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.301.
Повний текст джерелаFestus, Chioma, Anthony C. Ekennia, Aderoju A. Osowole, Lukman O. Olasunkanmi, Damian C. Onwudiwe, and Oguejiofo T. Ujam. "Synthesis, experimental and theoretical characterization, and antimicrobial studies of some Fe(II), Co(II), and Ni(II) complexes of 2-(4,6-dihydroxypyrimidin-2-ylamino)naphthalene-1,4-dione." Research on Chemical Intermediates 44, no. 10 (June 13, 2018): 5857–77. http://dx.doi.org/10.1007/s11164-018-3460-7.
Повний текст джерелаNOVAIS, H. M., and S. STEENKEN. "ChemInform Abstract: Reactions of Oxidizing Radicals with 4,6-Dihydroxypyrimidines as Model Compounds for Uracil, Thymine, and Cytosine." ChemInform 18, no. 21 (May 26, 1987). http://dx.doi.org/10.1002/chin.198721086.
Повний текст джерелаNOVAIS, H. M., and S. STEENKEN. "ChemInform Abstract: ESR Studies of Electron and Hydrogen Adducts of Thymine and Uracil and Their Derivatives and of 4,6-Dihydroxypyrimidines in Aqueous Solution." Chemischer Informationsdienst 17, no. 19 (May 13, 1986). http://dx.doi.org/10.1002/chin.198619054.
Повний текст джерела-, V. M. Sherekar, N. S. Padole -, and K. P. Kakade -. "Synthesis, Characterization and Biological Evaluation of 6-(5-Chloro-8-Hydroxynapthalene-2-yl)-4(4-Hydroxyphenyl)-4-5-Dihydroxypyrimidin-2(1h)-One." International Journal For Multidisciplinary Research 4, no. 6 (December 28, 2022). http://dx.doi.org/10.36948/ijfmr.2022.v04i06.1240.
Повний текст джерелаBeylkin, Diane, Gyanendra Kumar, Wei Zhou, Jaehyeon Park, Trushar Jeevan, Chandraiah Lagisetti, Rhodri Harfoot, Richard J. Webby, Stephen W. White, and Thomas R. Webb. "Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease." Scientific Reports 7, no. 1 (December 2017). http://dx.doi.org/10.1038/s41598-017-17419-6.
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