Дисертації з теми "Developmental biology/pattern formation"
Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями
Ознайомтеся з топ-50 дисертацій для дослідження на тему "Developmental biology/pattern formation".
Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.
Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.
Переглядайте дисертації для різних дисциплін та оформлюйте правильно вашу бібліографію.
Hunt, Gordon S. "Mathematical modelling of pattern formation in developmental biology." Thesis, Heriot-Watt University, 2013. http://hdl.handle.net/10399/2706.
Повний текст джерелаCruywagen, Gerhard C. "Tissue interaction and spatial pattern formation." Thesis, University of Oxford, 1992. http://ora.ox.ac.uk/objects/uuid:f242b785-9b46-4c21-a789-477b025ce4b3.
Повний текст джерелаBaker, Ruth E. "Periodic pattern formation in developmental biology : a study of the mechanisms underlying somitogenesis." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.418815.
Повний текст джерелаWilliamson, Carly Zoe. "A Computational Model of Divergent Pattern Formation in Caenorhabditis elegans and Caenorhabditis briggsae Vulval Development." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1460574181.
Повний текст джерелаSadeghi, Nazlie. "The N-cadherin prodomain: regulation of synpase formation «in vivo» and developmental expression pattern in the zebrafish central nervous system." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=19229.
Повний текст джерелаLe pro-domaine de la N-cadherin: Rôle dans la régulation de la synaptogenèse in vivo et expression pendant le développement du système nerveux central chez le poisson zébré. La formation de connections neuronales dans le système nerveux central (SNC) se produit lorsque des membranes pré et post-synaptiques nouvellement formées sont conditionnées à générer un complexe synaptique mature. Malgré notre compréhension limitée de la séquence précise d'évènements conduisant à la formation d'une synapse, la présence et le potentiel adhésif d'un petit nombre de molécules hautement spécialisées retrouvées sur certains sites pré et post-synaptiques semblent déterminer où et quand des synapses seront formées (Sperry et al, 1963; Fannon and Colman 1996; Craig et al, 2001). Selon les théories actuelles sur la synaptogenèse, un signalement intercellulaire par le biais de molécules adhésives présentes à certains sites de contact cellulaire conduit au recrutement graduel de constituants pré et post-synaptiques à ces sites, résultant ainsi en une maturation de la synapse. Dans la neurone pré-synaptique, il est conçu que les colis cellulaires (connus sous le nom de "piccolo-bassoon transport packets", "active zone precursor vesicles" ou tout simplement "transport packets" en anglais) livrent de grandes quantités de protéines aux synapses nouvellement générées (Zhai et al., 2001; Ziv and Garner 2004). Parce que la N-cadherin est une molécule adhésive prééminente de même qu'une constituante principale de ces colis cellulaires, nous avons émis l'hypothèse qu'elle pouvait jouer un rôle important aux origines du développement nerveux. En imageant des neurones "Rohon-Beard" de poissons zébrés à
Srivastava, Vinit. "Pattern formation in the mammalian striatum, the development of the thalamostriatal projection in the rodent." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0023/MQ50884.pdf.
Повний текст джерелаSaavedra, Pedro Almeida Dias Guedes. "Pattern formation and planar cell polarity in Drosophila larval development : insights from the ventral epidermis." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708010.
Повний текст джерелаCheesman, Sarah Emily. "Dorsal ventral patterning of the central nervous system : lessons from flies and fish /." view abstract or download file of text, 2003. http://wwwlib.umi.com/cr/uoregon/fullcit?p3113005.
Повний текст джерелаTypescript. Includes vita and abstract. Includes bibliographical references (leaves 95-102). Also available for download via the World Wide Web; free to University of Oregon users.
Schweickart, Robert Allen. "FRAZZLED PLAYS A ROLE IN THE FORMATION OF CELL DENSITY PATTERNS IN THE EARLY DROSOPHILA EMBRYO." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1545181299374722.
Повний текст джерелаMarín, de Mas Igor Bartolomé. "Development and application of novel model-driven and data-driven approaches to study metabolism in the framework of systems medicine." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/296313.
Повний текст джерелаLa presente tesis doctoral se centra en el desarrollo de herramientas computacionales que permitan el estudio de los mecanismos moleculares que ocurren dentro de la célula. Mas específicamente estudia el metabolismo celular desde diferentes puntos de vista usando y desarrollando métodos computacionales basados en diversas metodologías. Así pues en un primer capitulo se desarrolla un método basado en el analista de los flujos metabólicos en estado no estacional isotópico utilizando modelos cinéticos para estudiar el fenómeno de la canalización metabólica en hepatocitos. Este fenómeno modifica la topología metabólica alterando el fenotipo. Nuestro método nos permitió discriminar varios modelos con distintas topología prediciendo la existencia de canalización metabólica en la glucólisis. En el segundo capitulo se desarrolló un método para analizar el metabolismo tumoral teniendo en cuenta la heterogeneidad de poblaciones. En concreto estudiamos dos subpoblaciones extraídas de una linea celular de cáncer de próstata. Para ello utilizamos un modelo a gran escala de todo el metabolismo celular humano. El análisis reflejó la existencia de diferencias notables a nivel de vías metabólicas concretas, confiriendo a cada subpoblacion sensibilidades distintas a diferentes fármacos. En esta linea se demostró que mientras las células PC-3M eran sensibles al etomoxir e insensibles al calcitriol, las PC-3S presentaban una sensibilidad opuesta. En el tercero y ultimo capitulo de la tesis desarrollamos un nuevo método computacional que integra aproximaciones probabilísticas y mecanicistas para integrar diferentes tipos de datos en un análisis basado en modelos discretos. Para ello utilizamos como caso de concepto el estudio de la adaptación anómala al entrenamiento de pacientes con EPOC. El análisis reveló diferencias importantes a nivel de metabolismo energético en comparación con el grupo control.
Reed, Robert Dale Jr. "The evolution of pattern formation in butterfly wings." Diss., The University of Arizona, 2004. http://hdl.handle.net/10150/290156.
Повний текст джерелаYang, Xige. "MATHEMATICAL MODELS OF PATTERN FORMATION IN CELL BIOLOGY." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1542236214346341.
Повний текст джерелаCrawford, David Michael. "Analysis of biological pattern formation models." Thesis, University of Oxford, 1989. http://ora.ox.ac.uk/objects/uuid:aaa19d3b-c930-4cfa-adc6-8ea498fa5695.
Повний текст джерелаRen, Xiaojing. "Modeling pattern formation of swimming E.coli." Click to view the E-thesis via HKUTO, 2010. http://sunzi.lib.hku.hk/hkuto/record/B43704001.
Повний текст джерелаTewari, Aneesha G. (Aneesha Ghanhi). "Pattern formation and essential responses for regeneration in planarians." Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/122068.
Повний текст джерелаThesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2019
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references.
The fundamental requirements for regeneration are poorly understood. Planarians can robustly regenerate all tissues after injury, involving stem cells, patterning cues and a set of cellular and molecular responses collectively called the "missing tissue" or "regenerative" response. The missing tissue response has long been considered a fundamental requirement of planarian regeneration. follistatin, which encodes an extracellular Activin inhibitor, is required for the missing tissue response after head amputation, and for subsequent regeneration. We found that follistatin is required for the missing tissue response regardless of the wound context, but only causes regeneration failure after head amputation. This head regeneration failure involves follistatin-mediated regulation of Wnt signaling at wounds, and is not a consequence of a diminished missing tissue response.
We found that all tested contexts of regeneration, including head regeneration, could occur with a defective missing tissue response, however, at a slower pace. Our findings suggest that in the absence of major cellular and molecular programs induced by large injuries, regulation of wound-induced Wnt signaling to enable regenerative re-patterning along with continuous tissue turnover can mediate successful regeneration in essentially any wound context. Wnt signaling regulates primary body axis formation across the Metazoa, with high Wnt signaling specifying posterior identity. Whether a common Wnt-driven transcriptional program accomplishes this broad role is poorly understood. We identified genes acutely affected after Wnt signaling inhibition in the posterior of two regenerative species, the planarian Schmidtea mediterranea and the acoel Hofstenia miamia, which are separated by >550 million years of evolution.
Wnt signaling was found to maintain positional information in muscle and regional gene expression in multiple differentiated cell types. sp5, Hox genes, and Wnt pathway components are down-regulated rapidly after [beta]-catenin RNAi in both species. brachyury, a vertebrate Wnt target, also displays Wnt-dependent expression in Hofstenia. Planarian sp5 inhibits Wnt-dependent expression of trunk genes in the tail, promoting separate tail-trunk body domains. We propose that common regulation of a small gene set - Hox, sp5, and brachyury - might underlie the widespread utilization of Wnt signaling in primary axis patterning across the Bilateria.
by Aneesha G. Tewari.
Ph. D.
Ph.D. Massachusetts Institute of Technology, Department of Biology
Lewis, Mark A. "Analysis of dynamic and stationary biological pattern formation." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.276976.
Повний текст джерелаThomson, J. Ross. "Models of pattern formation on the primate visual cortex." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=55635.
Повний текст джерелаMarshall, Heather. "Retinoic acid and the developmental regulation of the Hoxb-1 gene during embryogenesis." Thesis, Open University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282309.
Повний текст джерелаRen, Xiaojing, and 任晓晶. "Modeling pattern formation of swimming E.coli." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B43704001.
Повний текст джерелаDuran, Nebreda Salvador 1987. "Artificial multicellularity and pattern formation." Doctoral thesis, Universitat Pompeu Fabra, 2016. http://hdl.handle.net/10803/403584.
Повний текст джерелаThis project has tackled unanswered questions regarding the origins of multicellular life and cooperation using artificial approaches, namely: artificial evolution and synthetic biology. These offer unique opportunities to watch the evolution of complexity unfold and complement the extensively used methods of characterization of extant multicellular systems and theoretical biology. In particular we have proposed new mechanisms to create periodical structures in synthetic systems and how differentiated multicellularity might arise from Darwinian entities.
Schrader, Jarmo. "Developmental biology of wood formation : finding regulatory factors through functional genomics /." Umeå : Dept. of Forest Genetics and Plant Physiology, Swedish Univ. of Agricultural Sciences, 2003. http://epsilon.slu.se/s292.pdf.
Повний текст джерелаFerguson, James. "THE SPATIAL AND TEMPORAL ROLE OF EZH2 IN SKULL BONE FORMATION." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1530898825341447.
Повний текст джерелаFregoso, Santiago. "Pattern and Mechanism of Calcium Mobilization During Embryonic Development in a Viviparous Snake, Virginia striatula." Digital Commons @ East Tennessee State University, 2010. https://dc.etsu.edu/etd/1712.
Повний текст джерелаJoy, Ryan Mears. "Dcbld2/esdn Is Essential For Proper Optic Tract Formation And Retinal Lamination." ScholarWorks @ UVM, 2016. http://scholarworks.uvm.edu/graddis/563.
Повний текст джерелаLiu, Chenli, and 刘陈立. "Formation of novel biological patterns by controlling cell motility." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46541913.
Повний текст джерелаpublished_or_final_version
Biochemistry
Doctoral
Doctor of Philosophy
Uygur, Aysu N. "Evolution of Morphology: Modifications to Size and Pattern." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11609.
Повний текст джерелаFu, Xiongfei, and 傅雄飞. "Quantitative study of pattern formation on a density-dependent motility biological system." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48199424.
Повний текст джерелаpublished_or_final_version
Physics
Doctoral
Doctor of Philosophy
So, Young Lee. "Initiation of Innate Immune Responses in the Freshwater Crayfish Pacifastacus leniusculus." Doctoral thesis, Uppsala University, Department of Evolutionary Biology, 2001. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-623.
Повний текст джерелаProphenoloxidase (proPO) is a key enzyme for generation of melanin and is activated by the proPO activating enzyme (ppA) to its active form, PO. The active ppA was purified and cloned from crayfish hemocytes and it is a typical serine proteinase containing a clip, a proline-rich, and a glycine-rich domain. A recombinant protein containing the clip-domain, with homology to horseshoe crab big defensin and mammalian â-defensin, had antibacterial activity in vitro against gram-positive bacteria.
The proPO activating system (proPO system) is triggered by lipopolysaccharides (LPS) or â-1,3-glucans. An LPS and â-1,3-glucan binding protein (LGBP) was characterized from crayfish hemocytes. The results of an LGBP antibody inhibition assay suggest that LGBP is directly involved in the proPO system.
The primary structure of a crayfish masquerade-like (mas) protein has homology to serine proteinases except for a substitution within the catalytic triad, which renders it without proteinase activity. The crayfish mas-like protein has also binding activity to various gram-negative bacteria and yeast. When the mas-like protein binds to microorganisms, it is processed by a proteolytic enzyme. The mas-like protein exhibited cell adhesion and opsonic activities suggesting that it plays a role in defense against parasites.
Karam, Sana. "Mechanisms of pattern formation in the developing cerebellum : role for Eph receptor gene family /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/10557.
Повний текст джерелаMelville, Heather. "Spatiotemporal analysis of apoptosis patterns in the developing brain of the Brd2-knockdown zebrafish embryo." Click here for download, 2009. http://proquest.umi.com/pqdweb?did=1851609811&sid=1&Fmt=2&clientId=3260&RQT=309&VName=PQD.
Повний текст джерелаNodine, Michael. "The Analysis of Two Receptor-like Kinases Redundantly Required for Pattern Formation during Arabidopsis Embryogenesis." Diss., The University of Arizona, 2007. http://hdl.handle.net/10150/194199.
Повний текст джерелаKershner, Leah. "RACK1 regulates point contact formation and local translation in neuronal growth cones." Kent State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=kent1524159362714285.
Повний текст джерелаConner, Rebecca. "The Effects of Adjacent Cell Fusion and Ultraviolet Radiation Exposure on Viral Plaque Formation with Herpes Simplex Virus Type I." TopSCHOLAR®, 1986. http://digitalcommons.wku.edu/theses/1906.
Повний текст джерелаKendall, Bruce Edward. "Spatial structure and transient periodicity in biological dynamics." Diss., The University of Arizona, 1996. http://hdl.handle.net/10150/187496.
Повний текст джерелаEasley-Neal, Courtney Nichelle 1981. "Synapse Formation in the Zebrafish Spinal Cord." Thesis, University of Oregon, 2011. http://hdl.handle.net/1794/12028.
Повний текст джерелаThis dissertation describes research to elucidate the early steps in the process of synapse formation in the zebrafish spinal cord. One question is how presynaptic proteins are trafficked and recruited to nascent synapses. Previous work has suggested two possible models of presynaptic transport, either (1) most presynaptic proteins are transported together or (2) two types of transport packets, synaptic vesicle (SV) protein transport vesicles (STVs) and Piccolo-containing active zone precursor transport vesicles (PTVs), transport the necessary components separately. We tested these models using in vivo imaging in zebrafish spinal cord and found that the recruitment of at least three distinct transport packets during presynaptic assembly of a glutamatergic synapse occurs in an ordered sequence. First, STVs are stabilized at future synaptic sites, then PTVs, followed by a third transport packet type carrying Synapsin, a cytosolic protein that can tether SVs to actin. These results identify an order to the assembly of the presynaptic terminal in vivo, suggesting that a single synaptogenic interaction may precipitate the cascade of recruitment steps. We next examined the Cadm/SynCAM family of cell adhesion molecules, a family of proteins that has been shown to be able to induce synapse formation in vitro and was thought to play a role in recruitment of presynaptic proteins. As the role of these proteins in vivo was not well understood, we chose to examine the role of the cadms in zebrafish spinal cord. We found that zebrafish possess six cadm genes, and all are expressed throughout the nervous system both during development and in the adult. We then looked at the role of one of the Cadms, Cadm2a, in vivo in the zebrafish spinal cord. We found that knockdown of cadm2a significantly decreases the ability of zebrafish embryos to respond to touch. We also found that there is a significant reduction in the number of synapses, as shown by immunohistochemistry, formed between Rohon-Beard and CoPA neurons, the first two cell types in the touch response circuit. These data suggest that Cadm2a plays an important role in synapse formation in vivo. This dissertation contains both my previously published and unpublished co-authored material.
Committee in charge: Monte Westerfield Chairperson; Philip Washbourne, Advisor; Judith Eisen, Member; Tory Herman, Member; Mike Wehr, Outside Member
Song, Yuntao. "Epigenetic repression of retinoic acid responsive genes for cardiac outflow tract formation." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1563295948947138.
Повний текст джерелаHatem, Iyad. "Hybrid multivariate classification technique and its application in tissue image analysis /." free to MU campus, to others for purchase, 2003. http://wwwlib.umi.com/cr/mo/fullcit?p3091929.
Повний текст джерелаVasanthi, G. "Hormones and Cuscuta Development Abscisic Acid And Its Conjugates-Endogenous Levels And Metabolism During Growth And Haustoria Formation." Thesis, Indian Institute of Science, 1994. http://hdl.handle.net/2005/102.
Повний текст джерелаKuerbitz, Jeffrey S. "Formation and Function of Amygdala Circuitry: Differentiation and Migration of Intercalated Cells (ITCs) and their Role in Fear, Depression and Social Behavior." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1535457845286194.
Повний текст джерелаZhang, Xinghao. "A Comprehensive Structure-Function Study of Neurogenin3 during Human Endocrine Cell Formation in the Pancreas and Intestine." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1583155296519998.
Повний текст джерелаVithayathil, Joseph. "Developmental and Post-natal Roles for ERK1/2 Signaling in the Hippocampus." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1435760090.
Повний текст джерелаDdumba, Hassan. "Repulsive-attractive models for the impact of two predators on prey species varying in anti-predator response." Thesis, Nelson Mandela Metropolitan University, 2011. http://hdl.handle.net/10948/d1010995.
Повний текст джерелаBury, Luke Andrew Dascenzo. "Examining Dynamic Aspects of Presynaptic Terminal Formation via Live Confocal Microscopy." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1435336355.
Повний текст джерелаLee, Jin. "How fast can we see? : the latency development in human infants to pattern, orientation, and direction-reversal visual evoked potentials." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:09c7d3e8-7031-43e4-b03a-fe2dba219ceb.
Повний текст джерелаPantazis, Periklis. "Role of endocytic trafficking during Dpp gradient formation." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2004. http://nbn-resolving.de/urn:nbn:de:swb:14-1106665288062-25959.
Повний текст джерелаPegg, Timothy Joseph. "Cell Wall Carbohydrate Modifications during Flooding-Induced Aerenchyma Formation in Fabaceae Roots." Miami University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=miami1626443795433208.
Повний текст джерелаPeralta, Angela. "Generation of A L. Hesperus embryonic cDNA library for the isolation of genes involved in early pattern formation." Scholarly Commons, 2010. https://scholarlycommons.pacific.edu/uop_etds/755.
Повний текст джерелаHu, Jimmy Kuang-Hsien. "Diverse Roles of Cell Signaling during Early and Late Phases of Limb Development." Thesis, Harvard University, 2011. http://dissertations.umi.com/gsas.harvard:10015.
Повний текст джерелаBentaya, Souhila. "Etude de la fonction de la protéine de liaison à l'ARN XSEB4R dans la formation de l'ectoderme chez le xénope." Doctoral thesis, Universite Libre de Bruxelles, 2013. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209490.
Повний текст джерелаDes travaux récents du laboratoire ont montré que le gène XSeb4R, codant pour une protéine de liaison à l'ARN à motif RRM, présente maternellement de manière ubiquitaire dans la blastula, interagit directement avec la région 3'UTR de l'ARNm VegT, stabilisant et stimulant sa traduction. La déplétion de XSEB4R inhibe la formation de l'endoderme et du mésoderme et sa surproduction produit l’effet inverse. Ces observations ont montré que XSeb4R joue un rôle essentiel via VegT dans la formation de l'endoderme et du mésoderme.
Dans cette étude, nous avons testé l’hypothèse selon laquelle XSeb4R jouerait également un rôle au pôle animal dans la spécification de l’ectoderme. Nos résultats montrent que la protéine XSEB4R lie les régions 3’UTR des transcrits Sox3, Zic2a et Zic2b. Nous avons observé que la surexpression de XSeb4R stabilise les transcrits maternels Sox3 et Zic2 a et b, et qu’elle active la traduction des transcrits Zic2b mais pas celle de Sox3 ou Zic2a. Enfin, nous avons montré que la perte de fonction de XSeb4R induit une expansion du mésoderme vers l’ectoderme dans l’embryon au stade blastula. Ces résultats démontrent que XSeb4R joue un rôle important dans la spécification de l’ectoderme chez l’embryon de xénope.
Doctorat en Sciences
info:eu-repo/semantics/nonPublished
Gogia, Neha. "Drosophila Eye Model to Study Dorso-Ventral (DV) Patterning and Neurodegenerative Disorders." University of Dayton / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1572279564626749.
Повний текст джерела