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1
Coltell, Oscar, Andrea Alvarez-Sala, Ignacio Gimenez-Alba, Edurne de la Camara, Rebeca Fernández-Carrión, José Sorlí, and Dolores Corella. "The Eveningness Chronotype and Lower Adherence to the Mediterranean Diet Are Associated With Depressive Symptoms in Older Subjects With Metabolic Syndrome." Current Developments in Nutrition 5, Supplement_2 (June 2021): 901. http://dx.doi.org/10.1093/cdn/nzab049_014.
Повний текст джерелаАнотація:
Abstract Objectives Studies have shown the importance of depression as a risk factor for several diseases. Likewise, currently there is great interest on the role of chronotype in depressive disorders. Similarly, associations between diet and depression have been reported. However, very few studies have analyzed the combined effect of diet and chronotype on depression. Our aim was to investigated the joint influence of the morning/evening chronotype and adherence to the Mediterranean diet (MeDiet) on depressive symptoms in older subjects with metabolic syndrome. Methods We analyzed 465 PREDIMED Plus-Valencia study participants (aged 55–75). We assessed depressive symptoms by the Beck Depression Inventory (BDI). A higher score indicated more severe depressive symptoms. Adherence to the MedDiet was evaluated by the 17-item MeDiet score. Chronotype was assessed with the Morningness-Eveningness Questionnaire (MEQ). A higher total score indicated morningness. The 5 MEQ cut-offs were: definitely morning type, moderately morning type, intermediate type, moderately evening type, and definitely evening type. Multivariable models with interaction terms were fitted. Results Depressive symptons were statistically higher in women (P = 1.5 × 10–8) and in type 2 diabetes participants (P < 0.01). Adherence to the MeDiet was inversely associated with depression in the whole population (P < 0.001) and no significant heterogeneity by sex or by diabetes status was detected (P-interactions < 0.05). The morningness-eveningness mean score was inversely associated with depression, being the association statistically higher when we used the 5-categories for chronotypes. In a multivariable regression model adjusted for sex, diabetes, age, body mass index and physical activity, both adherence to the MedDiet (beta = –0.28; P = 0.010) and the chronotype (beta = –0.90; P = 0.047) remained statistically associated with the BDI score, showing additive effects. When we tested the interaction terms between chronotype and MedDiet adherence (P = 0.498) no significant heterogeneity was found. Conclusions The eveningness chronotype was associated with higher depressive symptoms, but a higher adherence to the MeDiet (inversely related with depression) may counteract the chronotype risk in an additive effect. Funding Sources CIBEROBN 06/03/035, PROMETEO 17/2017, P1 1B201354.
2
Ayalon, Liat, and Michael A. Young. "A Comparison Of Depressive Symptons In African Americans And Caucasian Americans." Journal of Cross-Cultural Psychology 34, no. 1 (January 2003): 111–24. http://dx.doi.org/10.1177/0022022102239158.
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Sedysheva, Е. V., V. М. Levanov, А. В. Prokopenkova, and А. V. Gustov. "Psychological characteristics of patients with myotonia dystrophica and principles of their rehabilitation." Neurology Bulletin XXIX, no. 1-2 (March 15, 1997): 86–88. http://dx.doi.org/10.17816/nb79929.
Повний текст джерелаАнотація:
When testing psychological characteristics of personality in 20 patients with myotonia dystrophica using MMPI test, it was revealed forming of anxious-asthenic syndrome, typical for initial clinical symptons of the disease. With the main disease progression tendency to hypochondriac and depressive states is observed. Complex of medicamental and psychotherapeutic rehabilitation is offered.
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Martinez-cengotitabengoa, M., C. Bermudez-ampudia, M. P. Lopez, A. Garcia-alocen, I. Gonzalez-ortega, I. Zorrilla, and A. Gonzalez-pinto. "First bipolar episode and functionality: Relation with depressive symptoms and inflammation levels." European Psychiatry 33, S1 (March 2016): S122—S123. http://dx.doi.org/10.1016/j.eurpsy.2016.01.154.
Повний текст джерелаАнотація:
IntroductionIt is important to make an early and effective intervention from the first bipolar episode. The presence of depressive symptoms in the course of a manic episode could influence negatively the evolution and the prognosis of the patient. Inflammation and oxidative stress are also related with functionality.ObjectivesTo explore the relationship between depressive symptoms during a first episode of mania, inflammatory parameters and patient functionality during the follow-up.MethodWe included in the study 92 are patients with a first manic episode and 92 matched healthy controls. We compared 13 inflammatory/oxidative stress parameters measured at baseline (TFNα, IL6, PGE2, MCP1, TBARS, NO2, SOD, CAT, GSHTOT, GSSG, GSHfree, GPx, TAS) between both groups. Between patients, 46 presented pure mania (PM) (no depressive symptoms) and 46 mixed mania (MM) (with depressive symptoms). We explored the influence of inflammatory factors in functionality, exploring differences between PM and MM. To measure patients’ general functioning one year after illness onset, we used the Functional Assessment Short Test (FAST).ResultsWe found significant differences in TFNα, MCP1 and TBARS (higher in patients) and in SOD, GSHtot, GSSG, GSHfree, GPx and TAS levels (lower in patients). Only In MM group, there was a significant influence of SOD and GSHfree in FAST scores suggesting that a higher antioxidant levels at baseline the patient functionality improves one year after.ConclusionsSome parameters of oxidative stress at baseline are related with patient's functionality one year after the first episode of mania, but only when mania debuts with depressive symptons simultaneously.Disclosure of interestThe authors have not supplied their declaration of competing interest.
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Brokate, Barbara, Jens Reimer, and Helmut Hildebrandt. "Chrakteristik depressiver Symptome bei psychischen Erkrankungen und Multipler Sklerose – eine retrospektive Datenanalyse." Zeitschrift für Neuropsychologie 28, no. 3-4 (December 1, 2017): 197–205. http://dx.doi.org/10.1024/1016-264x/a000203.
Повний текст джерелаАнотація:
Zusammenfassung. In dieser retrospektiven Datenanalyse geht es um die Frage, ob depressiv Erkrankte, alkoholabhängige Patienten, schizophrene Patienten und Multiple-Sklerose-Patienten eine vergleichbare Struktur depressiver Symptome zeigen. Dabei sind die Identifikation spezifischer Symptome und die Möglichkeit der Gruppierung depressiver Symptome von besonderem Interesse. Weiter wird die Informationsverarbeitungsgeschwindigkeit als kognitiver Parameter in die Analysen einbezogen, da eine Verlangsamung bei vielen Erkrankungsgruppen zu erwarten ist. Bei 231 Patienten und 31 Kontrollpersonen zeigen sich signifikante Unterschiede in der Struktur depressiver Symptome zwischen den Gruppen, wobei die Intensität depressiver Symptome bei originär depressiven Patienten ausgesprochen hoch ist. Weiter sind depressive Patienten in der Informationsverarbeitungsgeschwindigkeit erheblich langsamer als alle anderen Gruppen. Die Ergebnisse werden mithilfe neuropsychologischer Konzepte der Depression und Multiple Sklerose erklärt.
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Mendes, M. S. "1941 – Depression and women's life cycle:comparative prevalence of depressive symptons in women along the life cycle in a portuguese community sample." European Psychiatry 28 (January 2013): 1. http://dx.doi.org/10.1016/s0924-9338(13)76884-6.
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Belbachir, S., M. Elkadiri, A. Ouanass, and Siham Belbachir. "LES SYMPTOMES RESIDUELS DANS LA DEPRESSION." International Journal of Advanced Research 9, no. 03 (March 31, 2021): 155–58. http://dx.doi.org/10.21474/ijar01/12568.
Повний текст джерелаАнотація:
Si la remission de la depression est lobjectif therapeutique principal, la frequence de remissions partielles reste elevee. Les symptomes les plus frequemment rapportes sont propres a la depression notamment lanxiete et lirritabilite, lhumeur depressive, lasthenie et les troubles du sommeil. Les etudes sur la depression avec symptomes residuels restent peu nombreuses et concernent surtout des populations de patients hospitalises ou a forme sevère de depression. La presence de symptomes residuels est associee a un taux de rechutes depressives plus eleve, jusqua 5 fois plus rapidement que chez les sujets en remission sans symptomes residuels, a une augmentation du taux de suicides, une consommation de soins importante et un handicap social prononce. Les symptomes residuels constitueraient un marqueur clinique pour le pronostic surtout en termes de rechute et chronicite et devraient faire lobjet de strategies therapeutiques specifiques. Il nous a paru pertinent de selectionner une population de patients deprimes suivi en consultation psychiatrique. Notre objectif principal etait danalyser la frequence des symptomes residuels après 8 a 12 semaines de traitement antidepresseur et detudier les caracteristiques cliniques et sociodemographiques de ces sujets. La persistance de symptomes residuels après traitement dun episode depressif majeur est retrouvee dans environ un tiers des cas. Il existe des liens etroits entre persistance de symptomes residuels a lissue dun episode depressif majeur, et risque de nouvel episode depressif, comme le soulignent a la fois les recommandations de groupes dexperts et de societes savantes, et les etudes cliniques menees sur ce sujet. Parmi les facteurs de risque de survenue dun episode ulterieur, le poids de la persistance de symptomes residuels pourrait même être superieur a celui du nombre depisodes depressifs anterieurs. Les propositions therapeutiques, en cas de symptomes residuels, sappuyant sur des outils pharmacologiques ou psychotherapiques, sont essentiellement de deux types : potentialisation non specifique du traitement antidepresseur anterieur et adjonction de traitement ciblant specifiquement les symptomes residuels retrouves chez chaque patient jusqua leur disparition. If the remission of depression is the main therapeutic objective, the frequency of partial remissions is high. The most commonly reported symptoms are specific to depression: anxiety and irritability, depressed mood, asthenia, and sleep disturbances. Studies on depression with residual symptoms are few and concern hospitalized patients or patients with severe forms of depression. The presence of residual symptoms is associated with a higher rate of depressive relapse, up to 5 times faster than in subjects in remission without residual symptoms, an increase in the suicide rate and social handicap pronounced. The residual symptoms would constitute a clinical marker for the prognosis especially in terms of relapse and chronicity and should be the subject of specific therapeutic strategies.It seemed appropriate to select a population of depressed patients followed by psychiatric consultation. Our main objective was to analyze the frequency of residual symptoms after 8 to 12 weeks of antidepressant treatment and to study the clinical and socio-demographic characteristics of these subjects. The persistence of residual symptoms after treatment of a major depressive episode is found in about a third of cases. There are close links between the persistence of residual symptoms after a major depressive episode, and the risk of a new depressive episode, as highlighted both by the recommendations of expert groups and learned societies, and clinical studies. The therapeutic proposals, in the event of residual symptoms, based on pharmacological or psychotherapeutic tools, are essentially of two types: non-specific potentiation of the previous antidepressant treatment and addition of treatment specifically targeting the residual symptoms found in each patient. There is an important consensus to continue therapeutic efforts until the disappearance of residual symptoms.
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Tae, Bárbara, Elisabeth Rosa Pelaggi, Julia Guglielmi Moreira, Jaques Waisberg, Leandro Luongo de Matos, and Gilberto D'Elia. "Impact of bariatric surgery on depression and anxiety symptons, bulimic behaviors and quality of life." Revista do Colégio Brasileiro de Cirurgiões 41, no. 3 (June 2014): 155–60. http://dx.doi.org/10.1590/s0100-69912014000300004.
Повний текст джерелаАнотація:
OBJECTIVE: To assess psychiatric symptoms, substance use, quality of life and eating behavior of patients undergoing bariatric surgery before and after the procedure. METHODS: We conducted a prospective longitudinal study of 32 women undergoing bariatric surgery. To obtain data, the patients answered specific, self-administered questionnaires. RESULTS: We observed a reduction in depressive and anxious symptoms and also in bulimic behavior, as well as an improved quality of life in the physical, psychological and environmental domains. There was also a decrease in use of antidepressants and appetite suppressants, but the surgery was not a cessation factor in smoking and / or alcoholism. CONCLUSION: a decrease in psychiatric symptoms was observed after bariatric surgery, as well as the reduction in the use of psychoactive substances. In addition, there was an improvement in quality of life after surgical treatment of obesity.
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Kübler, Andrea, Susanne Winter, Jochen Kaiser, Niels Birbaumer, and Martin Hautzinger. "Das ALS-Depressionsinventar (ADI):." Zeitschrift für Klinische Psychologie und Psychotherapie 34, no. 1 (January 2005): 19–26. http://dx.doi.org/10.1026/1616-3443.34.1.19.
Повний текст джерелаАнотація:
Zusammenfassung. Theoretischer Hintergrund: Bei der amyotrophen Lateralsklerose (ALS) handelt es sich um eine fortschreitende degenerative Erkrankung, die zu vollständigem motorischen Funktionsausfall führen kann. Depressive Stimmung bei ALS-Patienten wirkt sich verkürzend auf die verbleibende Lebensspanne aus. Zur quantitativen Erfassung von Depression bei ALS-Patienten werden Fragebögen verwendet, die die spezifische Situation der zunehmenden körperlichen Beeinträchtigung bis hin zur vollständigen Lähmung und künstlicher Ernährung und Beatmung nicht berücksichtigen. Fragestellung: Die Entwicklung eines speziell auf diese Patientengruppe ausgerichteten Inventars zur Messung depressiver Symptomatik. Methode: Das neu entworfene Inventar wurde gesunden Personen (93), ALS-Patienten (76) und depressiven Patienten (56) vorgelegt. Anhand der Ergebnisse wurde das ursprüngliche Inventar auf 12 Items reduziert (ADI-12). Ergebnis: 75% der ALS-Patienten wiesen depressive Symptome auf. Patienten mit ALS waren signifikant weniger depressiv als Patienten mit Depression. Schlussfolgerungen: Bei ALS-Patienten ist mit depressiver Verstimmung zu rechnen. Mit dem ADI-12 kann Depression auch noch bei schwerstbeeinträchtigten ALS-Patienten gemessen werden.
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Feldmann, Lisa, Iris Landes, Gerd Schulte-Körne, and Ellen Greimel. "Zurückweisungsempfindlichkeit bei Jugendlichen mit Depression." Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie 46, no. 2 (March 1, 2018): 143–53. http://dx.doi.org/10.1024/1422-4917/a000525.
Повний текст джерелаАнотація:
Zusammenfassung. Fragestellung: Als Zurückweisungsempfindlichkeit (ZE) wird die Disposition bezeichnet, Zurückweisung ängstlich zu erwarten, als wahrscheinlicher wahrzunehmen und daraufhin überzureagieren. In Studien konnte bereits gezeigt werden, dass Zurückweisungsempfindlichkeit bei depressiv erkrankten Erwachsenen erhöht ist und depressive Symptome bei Jugendlichen begünstigt. Bisher liegen jedoch noch keine Befunde zu dispositionellen Unterschieden hinsichtlich der Zurückweisungsempfindlichkeit bei depressiv erkrankten Jugendlichen vor. Methodik: In der vorliegenden Studie wurde daher erstmals mittels eines Fragebogens zur Zurückweisungsempfindlichkeit für Kinder und Jugendliche (FZE-K) geprüft, ob sich zwischen depressiven Jugendlichen und gesunden Jugendlichen Unterschiede in der Zurückweisungsempfindlichkeit und den Handlungsintentionen nach einer Zurückweisungssituation finden. Eingeschlossen wurden n = 28 Jugendliche mit Depression sowie n = 32 gesunde Jugendliche im Alter von 12 bis 17 Jahren. Ergebnisse: Die Ergebnisse zeigten, dass depressive Jugendliche eine höhere ZE aufweisen, Zurückweisung ängstlicher erwarten und die Wahrscheinlichkeit, zurückgewiesen zu werden, als höher einschätzen. Zudem gaben depressive Jugendliche im Vergleich zu der Kontrollgruppe an, stärker mit Selbstattribution und Resignation auf eine Zurückweisung zu reagieren. Diskussion: Die Ergebnisse lassen sich gut in das klinische Bild und in kognitive Theorien der Depression einordnen. In zukünftigen Studien sollte untersucht werden, ob sich entsprechende Interventionen positiv auf den Verlauf depressiver Erkrankungen auswirken.
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Gander, Manuela, and Anna Buchheim. "Internalisierende Symptome bei depressiven Jugendlichen." Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie 41, no. 1 (January 2013): 11–22. http://dx.doi.org/10.1024/1422-4917/a000206.
Повний текст джерелаАнотація:
Fragestellung: Um die Effektivität von Lehrerausbildungsprogrammen zu verbessern, ist es wichtig die unterschiedlichen Manifestationsformen der Depression bei jugendlichen Schüler und Schülerinnen gründlicher zu analysieren. Diese Studie untersucht die Ausprägung und Häufigkeit internalisierender Auffälligkeiten bei Jugendlichen mit depressiver Symptomatik und deren Zusammenhang zu einem erhöhten Suizidrisiko. Methodik: Mit dem Reynolds Adolescent Depression Scale-2, dem Youth Self-Report und dem Suicide Probability Scale wurden 403 Jugendliche an österreichischen allgemeinbildenden höheren Schulen (212 Mädchen und 191 Buben) im Alter zwischen 16 und 18 Jahren untersucht. Ergebnisse: 35 %, also über ein Drittel der Jugendlichen mit depressiven Symptomen, liegen zwar im internalisierend auffälligen Bereich, jedoch zeigen sie keine Auffälligkeiten im externalisierenden Bereich. Anhand der Regressionsanalyse zeigte sich, dass im internalisierenden Bereich insbesondere körperliche Beschwerden, Angst und Depressivität ausgeprägt sind. Neben diesen deuten aber auch Aufmerksamkeitsprobleme und schizoid zwanghaftes Verhalten auf eine depressive Symptomatik hin. Hinsichtlich des Suizidrisikos sind Depressivität, Angst, schizoid zwanghaftes Verhalten, soziale Probleme und aggressives Verhalten prädiktiv. Schlussfolgerungen: Diese Studienergebnisse werden im Zusammenhang mit bereits bestehenden Studien zur Erkennung von Verhaltensauffälligkeiten im schulischen Kontext diskutiert. Durch die Integration der Ergebnisse in Aus- und Fortbildung von Lehrpersonen soll eine Sensibilisierung auf den Bereich depressiver Jugendlicher mit internalisierenden Symptomen ermöglicht und die Identifikation erleichtert werden.
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Sawhney, Manisha, Seth Kunen, and Ashum Gupta. "Depressive Symptoms and Coping Strategies Among Indian University Students." Psychological Reports 123, no. 2 (December 21, 2018): 266–80. http://dx.doi.org/10.1177/0033294118820511.
Повний текст джерелаАнотація:
Depression is now the leading cause of disability worldwide, and globally more than 300 million people of all ages suffer from depression. Depression, despite its major health consequences, frequently goes unnoticed among university students, since their lives are often filled with symptoms normally associated with depression (e.g., loss of sleep, low energy, anxiety, and sadness). Successful adaptation to depression depends on the use of adequate coping strategies. The extent to which university students in India with high and low levels of depressive symptoms use adequate or inadequate coping strategies has not been evaluated. Based on the Center for Epidemiological Scale for Depression score, students were assigned to either the high depressive symptoms or the low depressive symptoms group. We used the Coping Response Inventory-Adult to determine the dominant coping strategies used by the two depressive symptoms groups. The high depressive symptom group resorted to more avoidant coping strategies than the low depressive symptom group, and women were more likely to use avoidant coping strategies than men.
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Laederach-Hofmann, K., and H. U. Fisch. "Diagnose und Therapie der Depression beim herzkranken Patienten." Therapeutische Umschau 60, no. 11 (November 1, 2003): 703–7. http://dx.doi.org/10.1024/0040-5930.60.11.703.
Повний текст джерелаАнотація:
Obwohl Depressionen und depressive Symptome bei medizinischen Patienten häufig beobachtet werden, wird die Depression bei diesen Patienten oft nicht diagnostiziert und nicht behandelt. Im Einzelfall mag ein depressiver Zustand leicht zu diagnostizieren sein; häufig ist dies aber nicht einfach. Der Begriff der normalen Stimmung lässt sich nicht quantifizieren, und für die Diagnose der Depression gibt es nur das klinische Urteil des untersuchenden Arztes und den Bericht des Patienten, nicht aber einen externen Goldstandard. Depression ist keine Diagnose, sondern ein Syndrom, das nicht primär nach Behandlung, sondern nach Differentialdiagnose ruft. Noch schwieriger ist die Diagnose der depressiven Komorbidität beim medizinisch kranken Patienten, weil sich die Symptome der Depression und Begleitsymptome der medizinischen Erkrankung wie zum Beispiel Energielosigkeit überschneiden. Obwohl depressive Zustände als Risikofaktor für die Prognose von Patienten mit koronarer Herzkrankheit respektive als Risikofaktor für einen Reinfarkt seit längerer Zeit bekannt sind, gibt es wenig Therapiestudien. Dies hängt damit zusammen, dass trizyklische Antidepressiva beim herzkranken Patienten kardiotoxische Effekte haben können. Erst die Serotonin-Reuptake-Hemmer erlauben eine Behandlung der Depression beim herzkranken Patienten mit niedrigem Risiko. Viele Befunde weisen darauf hin, dass die Prognose anderer medizinischer Erkrankungen, besonders der kardiovaskulären, durch depressive Komorbidität negativ beeinflusst wird. Die adäquate Diagnose und Behandlung der Depression wird, trotz der Komplexität der Diagnose der Depression, zunehmend von Bedeutung für die Innere Medizin und speziell die Kardiologie werden.
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Franche, Renée-Louise, Nancy Carnide, Sheilah Hogg-Johnson, Pierre Côté, F. Curtis Breslin, Ute Bültmann, Colette N. Severin, and Niklas Krause. "Course, Diagnosis, and Treatment of Depressive Symptomatology in Workers following a Workplace Injury: A Prospective Cohort Study." Canadian Journal of Psychiatry 54, no. 8 (August 2009): 534–46. http://dx.doi.org/10.1177/070674370905400806.
Повний текст джерелаАнотація:
Objectives: To estimate prevalence, incidence, and course of depressive symptoms and prevalence of mental health treatment following a workplace injury, and to estimate the association between depressive symptoms and return-to-work (RTW) trajectories. Method: In a prospective cohort study, workers filing a lost-time compensation claim for a work-related musculoskeletal disorder of the back or upper extremity were interviewed 1 month ( n = 599) and 6 months ( n = 430) postinjury. A high level of depressive symptoms was defined as 16 or more on the self-reported Center for Epidemiologic Studies—Depression (CES-D) Scale. The following estimates are reported: prevalence of high depressive symptom levels at 1 and 6 months postinjury; incidence, resolution, and persistence of high depressive symptom levels between 1 and 6 months; and prevalence of self-reported mental health treatment and depression diagnosis at 6 months postinjury. Results: Prevalence of high depressive symptom levels at 1 month and 6 months postinjury were 42.9% (95% CI 38.9% to 46.9%) and 26.5% (95% CI 22.3% to 30.7%), respectively. Among participants reporting high depressive symptom levels at 1 month postinjury, 47.2% (95% CI 39.9% to 54.5%) experienced a persistence of symptoms 6 months postinjury. By 6 months, 38.6% of workers who never returned to work or had work disability recurrences had high depressive symptom levels, compared with 17.7% of those with a sustained RTW trajectory. At 6–month follow-up, 12.9% (95% CI 5.8% to 20.1%) of participants with persistently high depressive symptom levels self-reported a depression diagnosis since injury and 23.8% (95% CI 14.7% to 32.9%) were receiving depression treatment. Conclusions: Depressive symptoms are pervasive in workers with musculoskeletal injuries, but transient for some, and seldom diagnosed as depression or treated.
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Begum, Musammet Rasheda, and Soma Chowdhury Biswas. "Changes in Depressive Symptoms During the Antenatal Period: A Cohort Study from Bangladesh." Indian Journal of Psychological Medicine 42, no. 6 (October 20, 2020): 519–24. http://dx.doi.org/10.1177/0253717620954337.
Повний текст джерелаАнотація:
Background: Antenatal depressive symptoms adversely affect the health and well-being of women, babies, and their families. This study aimed to explore the prevalence and probable associated factors of depressivse symptoms. Methods: A prospective cohort approach was adopted, and 435 pregnant women were assessed longitudinally at an antenatal clinic in the first, second, and third trimesters. Edinburgh Postnatal Depression Scale (EPDS) was used to measure self-reported depressive symptoms. The multivariate approach of the general linear model was used to evaluate the mean differences of depression scores among the trimesters. To investigate the associated factors of depressive symptoms, generalized estimating equation (GEE) was used to take into account the clustering effect. Results: More than half (58.13%) of the pregnant women had antenatal depressive symptoms in at least one trimester. Depressive symptoms decreased throughout the pregnancy; they were higher in the first trimester and declined toward the third trimester. Significant mean differences were found in depression scores among the three trimesters. GEE showed that trimester, education, family income, and body mass index (BMI) are significantly associated with antenatal depressive symptoms. Conclusions: First trimester is the most critical period for identification of depressive symptoms. At-risk women need to be treated. Proper education achievement, economic solvency, and adequate nutrition could reduce the depressive symptoms.
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WICHERS, M. C., G. H. KOEK, G. ROBAEYS, A. J. PRAAMSTRA та M. MAES. "Early increase in vegetative symptoms predicts IFN-α-induced cognitive-depressive changes". Psychological Medicine 35, № 3 (12 листопада 2004): 433–41. http://dx.doi.org/10.1017/s0033291704003526.
Повний текст джерелаАнотація:
Background. The vegetative symptoms of depression resemble the symptoms of malaise associated with activation of the inflammatory response system (IRS), and can be regarded as an expression of a central motivational state that resets the organism's priorities to promote recovery from infection. Early vegetative symptoms, however, may also contribute to the high rates of depression seen later in the course of immune activation. We hypothesized that the onset of vegetative-depressive symptoms early in the treatment with the pro-inflammatory cytokine IFN-α in chronic hepatitis C patients would increase the risk for subsequent depressive cognitions.Method. Sixteen patients eligible for IFN-α treatment and free of psychiatric disorders were recruited. The DSM-IV, the Multidimensional Fatigue Inventory, and the Montgomery–Asberg Depression Rating Scale (MADRS) were administered at baseline and 1, 2, 4, 8, 12 and 24 weeks after treatment was initiated. Cognitive-depressive and vegetative-depressive symptom clusters were constructed.Results. Fatigue and depression scores increased significantly during IFN-α treatment. Depression scores were highest at week 8 of treatment. First week increase in vegetative-depressive symptom score predicted cognitive-depressive symptom score at week 8 and at week 24.Conclusions. During IFN-α treatment, vegetative symptoms of depression appear earlier than, and are predictive of, their cognitive counterparts. This finding suggests that low mood state may in part be driven by the increase in early vegetative-depressive symptoms in the course of IFN-α-induced immune activation.
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Jungehülsing, G. J., K. Rossnagel, S. Roll, S. N. Willich, A. Villringer, J. Müller-Nordhorn, and C. H. Nolte. "Schlaganfallnachsorge wird von Hausärzten erbracht." Nervenheilkunde 28, no. 03 (2009): 135–37. http://dx.doi.org/10.1055/s-0038-1628586.
Повний текст джерелаАнотація:
ZusammenfassungHintergrund/Ziel: Die Post-Schlaganfall-Depression (PSD) ist die häufigste psychiatrische Komplikation. Wie die Versorgungssituation fern der akuten Behandlung des Schlaganfalls aussieht und von wem die Patienten betreut werden, ist bisher wenig untersucht. Ziel war es, die Versorgungssituation von Patienten vier Jahre nach einem Schlaganfall mit bleibenden Defiziten zu erfassen und speziell das Mitwirken von neurologischen und psychiatrischen Fachärzten und das Auftreten depressiver Symptome zu untersuchen.Methoden: Die Befragung wurde an Patienten der Berliner Akuter Schlaganfall Studie (BASS)-Einschlusskohorte durchgeführt. Es wurden nur Patienten mit erstmaligem, ischämischem, manifestem Schlaganfall berücksichtigt, die bleibende Defizite davontrugen.Ergebnisse: Die Rücklaufrate betrug 88%. Die primäre ärztliche Versorgung der Patienten lag mehrheitlich in der Hand von Hausärzten, selten bei Neurologen oder Kardiologen/Angiologen. Die Prävalenz berichteter mittelbis schwergradiger depressiver Symptome lag bei 15%, die der leichtgradigen depressiven Symptome bei 21%. Nur etwa ein Drittel der Patienten, die schwere depressive Symptome aufwiesen, erhielt eine medikamentöse, antidepressive Therapie.
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Kowalski, Jens T., Yvonne Radtke, Franziska Falkenhagen, Peter Kropp, Peter Zimmermann, Wolf Dieter Gerber, and Uwe Niederberger. "Verlaufsuntersuchung depressiver Symptomatik nach akuter Traumatisierung." Zeitschrift für Klinische Psychologie und Psychotherapie 41, no. 3 (October 2012): 211–18. http://dx.doi.org/10.1026/1616-3443/a000151.
Повний текст джерелаАнотація:
Hintergrund: Der Zusammenhang zwischen Akuter Belastungsstörung (ASD) und der Posttraumatischen Belastungsstörung (PTSD) ist vielfach untersucht. Wenige Erkenntnisse liegen über den klinischen Verlauf depressiver Symptome nach ASD vor. Fragestellung: Unterscheiden sich Patienten nach akuter Traumatisierung hinsichtlich der Entwicklung depressiver Symptome von Nicht-Traumatisierten? Methode: 39 akut Traumatisierte wurden mit einer gesunden Kontrollgruppe (KG, N=38) verglichen. Die ASD und die depressiven Symptome wurden mit standardisierten Verfahren (SKID, ASDS, DS) zu verschiedenen Messzeitpunkten untersucht. Ergebnisse: ASD-Patienten waren initial signifikant depressiver als die KG. Nach anfänglicher Beschwerderemission nahmen die depressiven Symptome bei der Gruppe der späteren PTSD-Patienten wieder zu. Schlussfolgerung: Depressive Symptome nach ASD sind sowohl bei Patienten mit als auch ohne nachfolgende PTSD häufig. Nach anfänglicher Remission der depressiven Beschwerden kann es zu einer Reexazerbation kommen.
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Fortinsky, Richard H., and Dorothy Wakefield. "CAREGIVER DEPRESSIVE SYMPTOM SEVERITY AMONG OLDER ADULTS WITH COGNITIVE VULNERABILITY." Innovation in Aging 3, Supplement_1 (November 2019): S385—S386. http://dx.doi.org/10.1093/geroni/igz038.1416.
Повний текст джерелаАнотація:
Abstract While caregivers of older adults with dementia often report considerable levels of depressive symptoms, much less is known about depressive symptoms among family members of older adults with depression or recent delirium. As part of an ongoing randomized clinical trial testing an in-home multidisciplinary team intervention for older adults with cognitive vulnerability due to dementia, depression, and/or delirium (care recipients, or CR) and their caregivers, in this presentation we report baseline data from the first 211 dyads enrolled in the trial to determine how caregiver depressive symptom severity is related to: CR diagnoses; CR cognitive impairment severity; and CR depressive symptom severity. CR diagnostic groups: Depression Only (n=49); Dementia Only (n=61); Depression and Dementia Only (n=47); Delirium Plus (n=54). Depressive symptom severity was measured using the Center for Epidemiologic Studies Depression Scale; CR cognitive symptom severity was measured using the Telephone Interview for Cognitive Status. Among CR, 57% were female, mean/sd age=77/6.9, 93% White; among caregivers, 64% were female, mean/sd age=66/13.7, 91% White, 55% spouses, 25% daughters, 9% sons. In multivariate linear regression models, which included covariates caregiver gender, relationship to CR, and number of hours/week providing care, we found that caregiver depressive symptom severity was less severe among caregivers of CR with Dementia Only compared to CR with Depression Only (b=-3.32; p=0.06); not associated with CR cognitive symptom severity; and significantly associated with CR depressive symptom severity (b=0.14; p<0.01). We conclude that family members of older adults with depression deserve greater attention to address their own depressive symptoms.
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Schmidt-Gies, Ulrike, and Reinhold Laessle. "Stressbezogene Symptome und Stressverarbeitung bei depressiven Mädchen." Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie 41, no. 6 (November 2013): 383–91. http://dx.doi.org/10.1024/1422-4917/a000254.
Повний текст джерелаАнотація:
Fragestellung: Depressive Störungen bei Kindern und Jugendlichen zeigen hohe Prävalenzraten. Für die Entstehung und Aufrechterhaltung von Depressionen in der Adoleszenz spielen unter anderem Stressfaktoren eine Rolle. Methodik: In der vorliegenden Studie wurde untersucht, welche Stresssymptome und welche Stressbewältigungsstrategien bei Mädchen mit einer Depression vorliegen. Nach DSM-IV diagnostizierte depressive Mädchen (n = 74) wurden mit einer nicht depressiven Kontrollgruppe bezüglich ihres Stresserlebens und ihrer Stressbewältigungsstrategien verglichen. Diese Variablen wurden anhand validierter Fragebögen zum Stresserleben und zur Stressverarbeitung erfasst. Resultate: Depressive Mädchen waren im Vergleich zur Kontrollgruppe durch eine signifikant stärkere Stressbelastung sowohl auf körperlicher als auch psychologischer Ebene charakterisiert. Auf den Skalen zur Messung der Stressverarbeitung hatten depressive Mädchen signifikant schlechtere Werte als die Kontrollgruppe. Schlussfolgerungen: Diese Querschnittsdaten legen nahe, dass bei depressiven Mädchen eine vorhandene Stressbelastung durch unzureichende Stressverarbeitung weiter bestehen bleibt oder sogar verstärkt wird. Inwieweit Stress eine depressive Erkrankung bei Jugendlichen auslöst oder erst in deren Folge auftritt, kann jedoch erst durch Längsschnittstudien geklärt werden.
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Lincke, Lena, and Michael Kölch. "Emotionale und depressive Störungen bei Kindern und Jugendlichen." Kinder- und Jugendmedizin 21, no. 02 (April 2021): 103–8. http://dx.doi.org/10.1055/a-1404-6527.
Повний текст джерелаАнотація:
ZUSAMMENFASSUNGBei depressiven Störungen im Kindes- und Jugendalter handelt es sich um ernstzunehmende Erkrankungen. Sie treten häufig gemeinsam mit anderen psychischen Störungen auf, neigen zur Chronifizierung und können die Funktionsfähigkeit und Teilhabechancen der Betroffenen langfristig beeinträchtigen. Alterstypische Symptome, wie eine gereizte Stimmung oder anhaltende Lustlosigkeit werden häufig nicht erkannt, da sie sich von den aus dem Erwachsenenalter bekannten Symptomen unterscheiden. Gerade in der Pubertät können depressive Symptome zudem schwer von alterstypischem Verhalten abzugrenzen sein. Das Auftreten depressiver Störungen lässt sich nicht auf eine einzige Ursache zurückführen. Neben neurobiologischen Faktoren tragen insbesondere schwere, belastende Lebensereignisse zu einem erhöhten Risiko bei, im Kindes- und Jugendalter an einer Depression zu erkranken. Die Behandlung depressiver Störungen orientiert sich am Schweregrad der Erkrankung und umfasst zumeist verhaltenstherapeutische Interventionen, teils in Kombination mit einer Medikation. Ergänzende Behandlungsansätze, wie Lichttherapie oder spezifische Ernährungszusätze werden auf ihre Wirksamkeit überprüft.
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Sapkota, N., B. Khadka, A. Tiwari, and A. Poudel. "Prevalence of Depression among Residents of old age homes in Eastern Nepal." Journal of Psychiatrists' Association of Nepal 8, no. 1 (November 14, 2019): 39–44. http://dx.doi.org/10.3126/jpan.v8i1.26335.
Повний текст джерелаАнотація:
Introduction: Geriatric depression is emerging mental disorder with old age. The present study was carried out to estimate the prevalence of depression among residents of elderly homes in Eastern Nepal and to measure the severity of the symptoms of depressive disorders.
Material And Method: This study involved residents of old age homes in four different districts of Eastern Nepal, the participants were heterogeneous with diverse cultural background and ethnicity. All elderly people of age 60 years and above living in the old age homes were at first informed about the rationale of our study, we took the informed verbal(as most of the subjects were illiterate) or written consent before going through our questionnaire which was translated into Nepali language by a panel of translators using repeated “forward backward procedure.” General Health questionnaire was applied to all subjects. Geriatric Depression scale (GDS) was then applied to those subjects whose score on GHQ-12 was ≥6 and the categorization of the subjects as normal, mild depressives or severe depressives was done.
Results: A total of 62 elderly people of 60 years and above from aforementioned old age homes were enrolled in our study, out of which, 48.38% of the respondents belong to age group of 60-69 years , 27.4% belong to the age group 70-79 and 24.2 % were 80 years and above. Out of total respondents, 56.46% showed normal mental status on our GHQ scale while 43.54% were screened to have some sorts of psychological problems. The GDS detected them with mild and severe depressive symptoms. Out of which, 81.48% had mild depressive symptoms while 18.52% were severe depressive symptoms. Prevalence of depression was found to be significantly related to family history of mental illness.
Conclusion: Most of the people living in the old age home in Eastern Nepal are found to have depressive symptoms among which majority have mild depressive symptoms and few have severe depressive symptoms. It depicts the miserable mental health of the elderly people in old age home.
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Heath, Nancy Lee, and Shana Ross. "Prevalence and Expression of Depressive Symptomatology in Students with and without Learning Disabilities." Learning Disability Quarterly 23, no. 1 (February 2000): 24–36. http://dx.doi.org/10.2307/1511097.
Повний текст джерелаАнотація:
The present study compared girls and boys with and without learning disabilities (LD) on mean reports of depressive symptoms, prevalence of depression and type of depressive symptoms reported. One hundred children with LD (46 girls, 54 boys) ana 104 children without LD (50 girls, 54 boys) were compared on the Children's Depression Inventory's (Kovacs, 1992) overall score, percent meeting the cutoff for depression (19) and subscale factor scores indicating symptom patterns. Results revealed that (a) mean level of depressive symptoms between students with and without LD did not differ but prevalence of depression was marginally different; (b) girls with LD reported higher mean levels of depressive symptoms and higher prevalence of depression than girls without LD, whereas there was no difference in mean levels of depressive symptoms or prevalence of depression for boys with or without LD; (c) students with LD reported more symptoms of ineffectiveness; (d) girls reported more negative mood and less interpersonal problems than boys; and (e) girls with LD reported more symptoms indicative of a loss of pleasure, negative self-esteem and interpersonal problems relative to their peers without LD, while boys with or without LD did not differ in their symptom type reports. Implications and limitations of the results are discussed with reference to previous research and directions for future investigation.
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Schennach, R., M. Riedel, M. Obermeier, F. Seemüller, M. Jäger, M. Schmauss, G. Laux, et al. "What are depressive symptoms in acutely ill patients with schizophrenia spectrum disorder?" European Psychiatry 30, no. 1 (January 2015): 43–50. http://dx.doi.org/10.1016/j.eurpsy.2014.11.001.
Повний текст джерелаАнотація:
AbstractBackground:Aim was to examine depressive symptoms in acutely ill schizophrenia patients on a single symptom basis and to evaluate their relationship with positive, negative and general psychopathological symptoms.Methods:Two hundred and seventy-eight patients suffering from a schizophrenia spectrum disorder were analysed within a naturalistic study by the German Research Network on Schizophrenia. Using the Calgary Depression Scale for Schizophrenia (CDSS) depressive symptoms were examined and the Positive and Negative Syndrome Scale (PANSS) was applied to assess positive, negative and general symptoms. Correlation and factor analyses were calculated to detect the underlying structure and relationship of the patient’s symptoms.Results:The most prevalent depressive symptoms identified were depressed mood (80%), observed depression (62%) and hopelessness (54%). Thirty-nine percent of the patients suffered from depressive symptoms when applying the recommended cut-off of a CDSS total score of > 6 points at admission. Negligible correlations were found between depressive and positive symptoms as well as most PANSS negative and global symptoms despite items on depression, guilt and social withdrawal. The factor analysis revealed that the factor loading with the PANSS negative items accounted for most of the data variance followed by a factor with positive symptoms and three depression-associated factors.Limitations:The naturalistic study design does not allow a sufficient control of study results for the effect of different pharmacological treatments possibly influencing the appearance of depressive symptoms.Conclusion:Results suggest that depressive symptoms measured with the CDSS are a discrete symptom domain with only partial overlap with positive or negative symptoms.
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Neyer, Sabrina, Michael Witthöft, Mark Cropley, Markus Pawelzik, Ricardo Gregorio Lugo, and Stefan Sütterlin. "Reduction of depressive symptoms during inpatient treatment is not associated with changes in heart rate variability." PLOS ONE 16, no. 3 (March 23, 2021): e0248686. http://dx.doi.org/10.1371/journal.pone.0248686.
Повний текст джерелаАнотація:
Vagally mediated heart rate variability (HRV) is a psychophysiological indicator of mental and physical health. Limited research suggests there is reduced vagal activity and resulting lower HRV in patients with Major Depressive Disorder (MDD); however little is actually known about the association between HRV and symptoms of depression and whether the association mirrors symptom improvement following psychotherapy. The aim of this study was to investigate the association between antidepressant therapy, symptom change and HRV in 50 inpatients (68% females; 17–68 years) with a diagnosis of MDD. Severity of depressive symptoms was assessed by self-report (Beck Depression Inventory II) and the Hamilton Rating Scale of Depression. Measures of vagally mediated HRV (root mean square of successive differences and high-frequency) were assessed at multiple measurement points before and after inpatient psychotherapeutic and psychiatric treatment. Results showed an expected negative correlation between HRV and depressive symptoms at intake. Depressive symptoms improved (d = 0.84) without corresponding change in HRV, demonstrating a de-coupling between this psychophysiological indicator and symptom severity. To our knowledge, this study is the first to examine an association between HRV and depressive symptoms before and after psychotherapy. The observed de-coupling of depression and HRV, and its methodological implications for future research are discussed.
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von Känel, Roland, Sonja Weilenmann, and Tobias R. Spiller. "Loneliness Is Associated with Depressive Affect, But Not with Most Other Symptoms of Depression in Community-Dwelling Individuals: A Network Analysis." International Journal of Environmental Research and Public Health 18, no. 5 (March 1, 2021): 2408. http://dx.doi.org/10.3390/ijerph18052408.
Повний текст джерелаАнотація:
There is a strong relationship between loneliness and depression, but depression is a heterogeneous disorder. We examined the profile of depressive symptoms most strongly related to loneliness. Study participants were 2007 community-dwelling individuals (median age 31 years, 70.4% women) who completed an online survey on loneliness (single-item question: “never”, “sometimes”, “often”), depressive symptoms (Patient Health Questionnaire-9) and demographics. The relationship between loneliness and depressive symptoms was evaluated with linear regression and network analyses. The prevalence of loneliness (sometimes or often) and of moderate depression was 47.1% and 24.0%, respectively. Loneliness explained 26% of the variance in the total depressive symptom score (p < 0.001), independent of covariates. This result was almost exclusively explained by the relationship with a single depression symptom (“feeling down, depressed, or hopeless”), irrespective of whether loneliness was treated as a nominal or continuous variable. The findings of our study suggest that the role of loneliness in depression should not only be investigated at the syndrome level, but also at the symptom level. Studies are warranted to test whether targeted treatment of depressive affect is particularly effective against loneliness.
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Sireling, L. I., P. Freeling, E. S. Paykel, B. M. Rao, and S. P. Patel. "Depression in General Practice:." British Journal of Psychiatry 147, no. 2 (August 1985): 119–26. http://dx.doi.org/10.1192/bjp.147.2.119.
Повний текст джерелаАнотація:
SummaryGeneral practice (GP) depressives prescribed an antidepressant were compared with those given other treatment, and with antidepressant-treated psychiatric out-patient depressives. GP depressives were considerably less severely ill than out-patients, with fewer depressive symptoms and shorter illness, as well as less primary and less endogenous depression. The two groups of GP depressives differed less, but those receiving other treatment tended to have less severe depression than those receiving antidepressants and were less likely to satisfy diagnostic criteria for depression. Depressives in GP differ considerably in clinical characteristics from psychiatric out-patient depressives, and clinical features influence the GP's decision to treat with antidepressants.
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Mulholland, Ciaran, and Stephen Cooper. "The symptom of depression in schizophrenia and its management." Advances in Psychiatric Treatment 6, no. 3 (May 2000): 169–77. http://dx.doi.org/10.1192/apt.6.3.169.
Повний текст джерелаАнотація:
Depression is a frequently occurring symptom in schizophrenia. While today it is often underrecognised and under-treated, historically such symptoms were the focus of much attention. Affective symptoms were used by Kraepelin as an important criterion with which to separate dementia praecox from manic–depressive illness. Kraepelin also recognised the importance of depression as a symptom in schizophrenia and identified several depressive subtypes of the illness. Mayer-Gross emphasised the despair that often occurs as a psychological reaction to acute psychotic episodes and Bleuler considered depression to be one of the core symptoms of schizophrenia.
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Gump, Brooks B., Jacki Reihman, Paul Stewart, Ed Lonky, Tom Darvill, Douglas A. Granger, and Karen A. Matthews. "Trajectories of maternal depressive symptoms over her child's life span: Relation to adrenocortical, cardiovascular, and emotional functioning in children." Development and Psychopathology 21, no. 1 (January 2009): 207–25. http://dx.doi.org/10.1017/s0954579409000133.
Повний текст джерелаАнотація:
AbstractMaternal depression has a number of adverse effects on children. In the present study, maternal depressive symptoms were assessed (using the Center for Epidemiological Studies Depression Scale) when their child was 3 months, 6 months, 1 year, 2 years, 4.25 years, 6 years, 7 years, 8 years, and 10 years of age. At 9.5 years of age, children's (94 females, 82 males) depressive symptoms as well as cardiovascular and cortisol levels during baseline and two psychologically stressful tasks were measured. Using multilevel modeling, maternal depressive symptom trajectories were considered in relation to their child's adrenocortical and cardiovascular responses to acute stress. Our goal was to determine maternal depressive symptom trajectories for children with elevated cardiovascular and cortisol reactivity to acute stress and elevated depressive symptoms. In general, those mothers with chronically elevated depressive symptoms over their child's life span had children with lower initial cortisol, higher cardiac output and stroke volume in response to acute stress, lower vascular resistance during acute stress tasks, and significantly more depressive symptoms at 9.5 years of age. These results are discussed in the context of established associations among hypothalamic–pituitary–adrenal axis dysregulation, depression, and cardiovascular disease.
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Morawski Mew, Andea, Diane Holditch-Davis, Michael Belyea, Margaret Shandor Miles, and Anne Fishel. "Correlates of Depressive Symptoms in Mothers of Preterm Infants." Neonatal Network 22, no. 5 (January 2003): 51–60. http://dx.doi.org/10.1891/0730-0832.22.5.51.
Повний текст джерелаАнотація:
Purpose: To identify factors related to depressive symptoms in mothers of preterm infants and to changes in depressive symptoms between hospitalization and when the infant was six months corrected age and to determine whether these factors differentiate mothers at high risk for depression from mothers at low risk for depression.Design: Correlational.Sample: During hospitalization, 39 mothers of preterm infants and, at six months corrected infant age, 34 mothers of preterm infants.Main Outcome Variable: Depressive symptoms as measured on the Center for Epidemiological Studies Depression scale.Results: At enrollment, 19 mothers (48.7 percent) had elevated depressive symptom scores. When the infants were six months corrected age, mean scores had decreased by 36 percent, and only 20 percent of the mothers had elevated scores. During hospitalization, the correlates of depressive symptoms were similar to the factors that differentiated between mothers at high risk and those at low risk for depression. However, the correlates of depressive symptoms during hospitalization were different from correlates of changes in depressive symptoms between hospitalization and six months corrected infant age. Identifying correlates of maternal depressive symptoms may lead to earlier identification and treatment of women at risk for depression, thereby decreasing the negative effects on infant development.
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Moon, Hye-Ri, Jingnan Zhang, Su-In Yoon, and Jin-Ah Cho. "Gastrointestinal Symptoms in Korean Adults with Depressive Symptoms." Research Institute of Human Ecology 26, no. 2 (August 31, 2022): 27–35. http://dx.doi.org/10.36357/johe.2022.26.2.27.
Повний текст джерелаАнотація:
Background/Objectives: Recent research has revealed gastrointestinal (GI) symptoms are one of the most prominent clinical manifestations of depression. The goal of this study is to find out the link between GI symptoms and depressive symptoms in a population of individuals who have not yet diagnosed with depression.
Methods: A total of 179 research participants were recruited offline and online, with 134 in the normal group and 45 in the group with depressive symptoms. The subjects' GI function and symptoms were evaluated with a validated GI questionnaire, and depressive symptoms were assessed with the Hamilton Depression Rating Scale (HDRS). The statistics were examined using SPSS version 26.
Results: Those with depressive symptoms were significantly more likely to be single, have a higher level of education, and engage in significantly fewer physical activities than those in the control group. In addition, the depressive symptom group experienced significantly more stomach discomfort, heartburn, regurgitation, abdominal rumbling, bloating, empty feeling, nausea, vomiting, loss of appetite, postprandial fullness, worsening stool issues, and GI pain compared to the normal group.
Conclusion/Implications: In this study, we discovered an intriguing lifestyle phenotype within the depressive symptom group as well as a link between depressive symptoms and GI symptoms. This research indicates that psychological variables play a substantial impact in the presence of gastrointestinal problems.
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Spinhoven, Philip, Karin Roelofs, Jacqueline GFM Hovens, Bernet M. Elzinga, Patricia van Oppen, Frans G. Zitman, and Brenda WJH Penninx. "Personality, Life Events and the Course of Anxiety and Depression." European Journal of Personality 25, no. 6 (November 2011): 443–52. http://dx.doi.org/10.1002/per.808.
Повний текст джерелаАнотація:
Using data from the Netherlands Study of Depression and Anxiety, we examined among 1322 participants with a DSM–IV diagnosis of depression or anxiety: (i) whether positive and negative life events influence 1–year course of anxiety and depressive symptoms; (ii) whether personality traits (neuroticism and extraversion) predict symptom course and moderate the impact of life events on symptom course; and (iii) whether life events mediate relationships of neuroticism and extraversion with symptom course. Negative life events were predictive of both anxiety and depressive symptoms, while positive life events predicted the course of depressive symptoms only. Personality traits had significant predictive and moderating effects on symptom course, though these effects were rather small. Copyright © 2011 John Wiley & Sons, Ltd.
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Escafit-Schülke, M. L., and H. P. Volz. "Effekte von Agomelatin bei depressiven Patienten im Praxisalltag." Nervenheilkunde 34, no. 10 (2015): 809–17. http://dx.doi.org/10.1055/s-0038-1627629.
Повний текст джерелаАнотація:
ZusammenfassungGegenstand und Ziel: Die nicht interventionelle Studie VIVRE (Valdoxan® ImproVes depRession with anxiEty symptoms) untersuchte, inwieweit das Antidepressivum Agomelatin (Valdoxan®) unter Praxisbedingungen auch soziale Funktionsfähigkeit und Angstsymptome depressiver Patienten beeinflusst. Methoden: 1 891 depressive Patienten wurden mit Agomelatin von 616 Ärzten drei Monate behandelt. Clinical-Global-Impressions (CGI) Skala, Patient-Global-Impressions (PGI) Skala, COVIAngst-Skala und Sheehan-Disability-Scale (SDS) wurden eingesetzt. Ergebnisse: Laut CGI und PGI lag die Responderrate jeweils bei 82,1% bzw. 73,1%, die Remissionrate jeweils bei 39,9% bzw. 47,6%. Angstsymptome der Depression verbesserten sich in allen COVIItems bei über 80% der Patienten. Die soziale Funktionsfähigkeit verbesserte sich in den SDSBereichen Arbeit/Schule, soziale Kontakte und Familienleben/Häusliche Verpflichtungen bei über 90% der Patienten. Die Verträglichkeit von Agomelatin wurde bei 98,2% der Patienten als “sehr gut/gut” bewertet. UAWs traten bei 2,6% der Patienten auf. Schlussfolgerung: Agomelatin zeigte im Praxisalltag eine umfassende Wirkung auf depressive Symptome, Angstsymptome der Depression und soziale Funktionsfähigkeit bei guter Verträglichkeit.
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Desmet, Mattias, Stijn Vanheule, and Paul Verhaeghe. "DEPENDENCY, SELF-CRITICISM, AND THE SYMPTOM SPECIFICITY HYPOTHESIS IN A DEPRESSED CLINICAL SAMPLE." Social Behavior and Personality: an international journal 34, no. 8 (January 1, 2006): 1017–26. http://dx.doi.org/10.2224/sbp.2006.34.8.1017.
Повний текст джерелаАнотація:
Several theorists have suggested that interpersonal dependency and excessive self-criticism are characteristics of personalities prone to depression. Here the results of a study are presented in which the hypothesis that these personality styles are connected to specific depressive symptoms in a sample of depressed outpatients (N = 163) was evaluated. Hypotheses were that dependency is specifically associated with the somatic symptom cluster of the Beck Depression Inventory-II (Beck, Steer, & Brown, 1996) and that self-criticism is specifically associated with the cognitive symptom cluster. In measuring the personality styles, the Depressive Experiences Questionnaire (Blatt, D'Affliti, & Quinlan, 1976) was used. No evidence suggesting that dependency is specifically connected to somatic depressive symptoms was found. Self-criticism was specifically associated with cognitive depressive symptoms. However, the results suggest that content overlap might explain the relationship between self-criticism and cognitive depressive symptoms.
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Luoma, I., M. Korhonen, and R. Salmelin. "Maternal Depressive Symptom Trajectories and Psychosocial Functioning in Young Adults: A 27-year Longitudinal Study." European Psychiatry 41, S1 (April 2017): S144. http://dx.doi.org/10.1016/j.eurpsy.2017.01.1984.
Повний текст джерелаАнотація:
IntroductionMaternal depression is a well-known risk factor for child development. Longitudinal studies extending from pregnancy to adulthood, however, are rare.ObjectivesThe aim of the study was to investigate whether maternal high depressive symptom trajectories (chronic or intermittent depressive symptom patterns) from pregnancy to the adolescence of the children predict lower adaptive functioning or higher levels of emotional or behavioural symptoms in young adults.MethodsThe sample comprised 329 first-time mothers from maternity centres in Tampere, Finland. Maternal depressive symptoms were assessed with the Edinburgh Postnatal Depression Scale (EPDS) antenatally and at two months, six months, 4–5 years, 8–9 years and 16–17 years after delivery. A model including four symptom trajectories (very low, low-stable, high-stable and intermittent) was selected to describe the symptom patterns over time. Adaptive functioning and problems of the children (n = 144) were assessed by the Adult Self Report forms (Achenbach & Rescorla) at the age of 27 years.ResultsHigh maternal depressive symptom trajectories did not predict self-reported lower adaptive functioning of the children in adulthood. However, children of mothers with chronic or intermittent depressive symptom patterns reported higher levels of internalising problems as well as symptoms of depression and anxiety in young adulthood than the children of mothers with very low or low stable symptom patterns.ConclusionsHigh maternal depressive symptom trajectories predict higher levels of emotional symptoms of children in young adulthood. The mechanisms of intergenerational transmission are important topics for further research.Disclosure of interestThe authors have not supplied their declaration of competing interest.
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Martens, E. J., O. R. F. Smith, J. Winter, J. Denollet, and S. S. Pedersen. "Cardiac history, prior depression and personality predict course of depressive symptoms after myocardial infarction." Psychological Medicine 38, no. 2 (September 17, 2007): 257–64. http://dx.doi.org/10.1017/s0033291707001377.
Повний текст джерелаАнотація:
BackgroundAlthough many studies have focused on post-myocardial infarction (MI) depression, there is limited information about the evolution and determinants of depressive symptoms in the first year post-MI. Therefore we examined (1) the course of depressive symptoms during the first year post-MI and (2) the predictors of these symptom trajectories.MethodTo assess depressive symptoms, 287 patients completed the Beck Depression Inventory during hospitalization for MI, and 2, and 12 months post-MI. Personality was assessed with the Type-D scale during hospitalization. We used latent class analysis to examine the evolution of depressive symptoms over a 1-year period and multinomial logit regression analyses to examine predictors of these symptom trajectories.ResultsThe course of depressive symptoms was stable during the first year post-MI. Four groups were identified and classified as non-depressed [40%, intercept (IC) 2.52], mildly depressed (42%, IC 6.91), moderately depressed (14%, IC 13.73) or severely depressed (4%, IC 24.54). In multivariate analysis, cardiac history (log ORsevere 2.93, p=0.02; log ORmoderate 1.81, p=0.02; log ORmild 1.46, p=0.01), history of depression (log ORsevere 4.40, p<0.001; log ORmoderate 1.97, p=0.03) and Type-D personality (log ORsevere 4.22, p<0.001; log ORmoderate=4.17, p<0.001; log ORmild 1.66, p=0.02) were the most prominent risk factors for persistence of depressive symptoms during the first year post-MI.ConclusionsSymptoms of depression tend to persist during the first year post-MI. Cardiac history, prior depression and Type-D personality were identified as independent risk factors for persistence of depressive symptoms. The results of this study strongly argue for routine psychological screening during hospitalization for acute MI in order to identify patients who are at risk for chronicity of depressive symptoms and its deleterious effects on prognosis.
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Althaus, A., T. Kanis, A. Spottke, K. Eggert, I. Liepelt, D. Berg, F. Schneider, and R. Dodel. "Benchmarking in der Patientenversorgung." Nervenheilkunde 26, no. 04 (2007): 277–80. http://dx.doi.org/10.1055/s-0038-1626859.
Повний текст джерелаАнотація:
ZusammenfassungDepression ist die häufigste psychische Begleiterkrankung der Parkinson-Erkrankung mit einer Prävalenz von 40 bis 50% und führt zu einer deutlichen Minderung der Lebensqualität der Patienten. Die adäquate Versorgung der Patienten ist als unzureichend einzustufen. Ziel der Studie im Rahmen des Modellvorhabens „Benchmarking im Gesundheitswesen” (gefördert vom Bundesministerium für Gesundheit) ist, die Behandlung und Versorgung von Parkinson-Patienten mit Depression zu verbessern. Das Vorhaben ist in drei Abschnitte gegliedert: 1. Pilotstudie: Erhebung der Häufigkeit der Depression und Beschreibung der Versorgung dieser Patienten sowie die Entwicklung eines validen und praktikablen Fragebogens. 2. Hauptstudie: Qualitätsmessung der Versorgung mittels Benchmarking an 20 Zentren (Kliniken, niedergelassene Neurologen) und Entwicklung eines Verhaltenstherapiemoduls. 3. Abschlussphase: Entwicklung eines Versorgungsalgorithmus für die tägliche Praxis. Die Pilotstudie wurde mit 70 Patienten durchgeführt. Das Vorkommen depressiver Symptome variierte erwartungsgemäß mit den eingesetzten Depressionsinventaren: Die Häufigkeit depressiver Symptome unabhängig von ihrem Schweregrad variierte von 40,6% (BDI) über 47,1% (MADRS) bis 52,2% (PHQ-D). Gemäß dem BDI wiesen 24,6% der untersuchten Patienten milde bis mäßige und 15,9% schwere depressive Symptome auf. 24,3% der Patienten erhielten eine medikamentöse antidepressive Therapie: 10,0% wurden mit tri- oder tetrazyklischen Antidepressiva, 8,6% mit SSRIs und 5,7% erhielten andere Antidepressiva. Von den Patienten mit gemäß dem BDI schwerer depressiver Symptomatik (n = 11) wurden nur 54,5% antidepressiv behandelt.Die Daten der Pilotstudie zeigen, dass die Versorgung von Parkinson-Patienten mit depressiven Symptomen nicht ausreichend ist.
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Bus, B. A. A., R. M. Marijnissen, S. Holewijn, B. Franke, N. Purandare, J. de Graaf, M. den Heijer, J. K. Buitelaar, and R. C. Oude Voshaar. "Depressive symptom clusters are differentially associated with atherosclerotic disease." Psychological Medicine 41, no. 7 (December 10, 2010): 1419–28. http://dx.doi.org/10.1017/s0033291710002151.
Повний текст джерелаАнотація:
BackgroundDepression increases the risk of subsequent vascular events in both cardiac and non-cardiac patients. Atherosclerosis, the underlying process leading to vascular events, has been associated with depression. This association, however, may be confounded by the somatic-affective symptoms being a consequence of cardiovascular disease. While taking into account the differentiation between somatic-affective and cognitive-affective symptoms of depression, we examined the association between depression and atherosclerosis in a community-based sample.MethodIn 1261 participants of the Nijmegen Biomedical Study (NBS), aged 50–70 years and free of stroke and dementia, we measured the intima–media thickness (IMT) of the carotid artery as a measure of atherosclerosis and we assessed depressive symptoms using the Beck Depression Inventory (BDI). Principal components analysis (PCA) of the BDI items yielded two factors, representing a cognitive-affective and a somatic-affective symptom cluster. While correcting for confounders, we used separate multiple regression analyses to test the BDI sum score and both depression symptom clusters.ResultsWe found a significant correlation between the BDI sum score and the IMT. Cognitive-affective, but not somatic-affective, symptoms were also associated with the IMT. When we stratified for coronary artery disease (CAD), the somatic-affective symptom cluster correlated significantly with depression in both patients with and patients without CAD.ConclusionsThe association between depressive symptoms and atherosclerosis is explained by the somatic-affective symptom cluster of depression. Subclinical vascular disease thus may inflate depressive symptom scores and may explain why treatment of depression in cardiac patients hardly affects vascular outcome.
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Shin, Dayeon, Nitin Shivappa, James R. Hébert, and Kyung Won Lee. "Examining Regional Differences of Dietary Inflammatory Index and Its Association with Depression and Depressive Symptoms in Korean Adults." International Journal of Environmental Research and Public Health 17, no. 9 (May 5, 2020): 3205. http://dx.doi.org/10.3390/ijerph17093205.
Повний текст джерелаАнотація:
The relationship between the dietary inflammatory index (DII®) and depression and depressive symptoms in South Korean adults remains unclear. This study aimed to examine the overall relationship between the DII and depression in South Korea and to evaluate the association between the DII and depressive symptoms and depression across regions among Korean adults aged ≥19 years. A total of 15,929 study participants were selected from the Korea National Health and Nutrition Examination Survey (KNHANES) 2014–2017. Energy-adjusted (E-DII) scores were calculated using 24-h dietary recall data. Depression and depressive symptoms were measured on the basis of the Korean version of the Patient Health Questionnaire 9-item scale, a doctor’s diagnosis of depression, and self-reported depressive symptom-related questionnaire. Overall, 4.2% of the participants had depression, with notable gender differences (i.e., 2.4% in men and 6.2% in women). Korean adults residing in the Capital area, Chungcheong-do and Jeju-do, and with diets in the highest tertile of the E-DII (most pro-inflammatory diet) had significantly increased odds of having depression and depressive symptoms compared with those in the lowest tertile of the E-DII (most anti-inflammatory diet) after controlling for covariates (adjusted odds ratio (AOR): 1.44, 95% confidence interval (CI): 1.04–1.99; AOR 2.97, 95% CI 1.36–6.52; AOR 4.06, 95% CI 1.56–10.53, respectively). No association between the E-DII and depression/depressive symptoms was found in other regions of South Korea. A pro-inflammatory diet is associated with greater odds of depression and depressive symptoms, with distinct regional differences. The present study provides evidence regarding existing regional differences in the association of the E-DII with depression and depressive symptoms.
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Zimmerman, Mark, Caroline Balling, Iwona Chelminski, and Kristy Dalrymple. "Understanding the severity of depression: do nondepressive symptoms influence global ratings of depression severity?" CNS Spectrums 25, no. 4 (November 12, 2019): 557–60. http://dx.doi.org/10.1017/s1092852919001548.
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AbstractObjective.Almost all depression measures have been developed without discussing how to best conceptualize and assess the severity of depression. It is therefore not surprising that measures differ in both how items are rated and item content. The question that we address in the present report from the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project is whether a measure of depression severity should include symptoms that are frequent in depressed patients but are defining features of other disorders (eg, anxiety, irritability)Methods.Patients were evaluated with a semi-structured interview and severity ratings were made of each symptom of major depressive disorder (MDD) as well as anxiety, irritability, and somatization. Patients were also rated on the Clinical Global Index of severity (CGI).Results.Three of the 5 nondepressive symptoms (psychic anxiety, somatic anxiety, and subjective anger) were significantly correlated with the CGI. The correlation between the sum of all 5 nondepressive symptoms and the CGI was significantly lower than the correlation between the sum of the depressive symptom severity ratings (0.12 vs 0.52, z = 11.0, p < .001). The partial correlation between the CGI and the nondepressive symptom severity ratings (after controlling for the total depressive symptom ratings) was nonsignificant.Discussion.After accounting for the severity of depressive symptoms, the severity of the nondepressive symptoms was not associated with global ratings of depressive severity. These findings raise questions regarding the appropriateness of including ratings of anxiety, irritability, and somatization on a measure that purportedly assesses the severity of depression.
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Brenne, Elisabeth, Jon Håvard Loge, Stein Kaasa, Ellen Heitzer, Anne Kari Knudsen, and Elisabet Wasteson. "Depressed patients with incurable cancer: Which depressive symptoms do they experience?" Palliative and Supportive Care 11, no. 6 (February 7, 2013): 491–501. http://dx.doi.org/10.1017/s1478951512000909.
Повний текст джерелаАнотація:
AbstractObjective:Diagnosing depressive disorders in palliative care is challenging because of the overlap between some depressive symptoms and cancer-related symptoms, such as loss of appetite and fatigue. In order to improve future assessment of depression in palliative care, depressive symptoms experienced by patients receiving pharmacological treatment for depression were assessed and compared to the American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV) criteria for major depressive disorder.Method:Thirty Norwegian (n = 20) and Austrian (n = 10) patients with advanced cancer were included. Semistructured interviews on symptom experiences were conducted and transcribed verbatim. By the phenomenographic method, patients' symptom experiences were extracted and sorted by headings, first individually and then across patients. The patients subsequently rated 24 symptoms numerically including the DSM-IV depression criteria.Results:Lowered mood and a diminished motivational drive were prominent and reflected the two main DSM-IV symptom criteria. A relentless focus on their actual situation, restlessness, disrupted sleep, feelings of worthlessness, feelings of guilt, and thoughts of death as a solution were variably experienced. Appetite and weight changes, fatigue and psychomotor retardation were indistinguishable from cancer symptoms. All these symptoms reflected DSM-IV symptom criteria. Some major symptoms occurred that are not present in the DSM-IV symptom criteria: despair, anxiety, and social withdrawal. The numerical ratings of symptoms were mainly in accordance with the findings from the qualitative analysis.Significance of results:Despair, anxiety, and social withdrawal are common symptoms in depressed patients with incurable cancer, and, therefore, hypothesized as candidate symptom criteria. Other symptom criteria might need adjustment for improvement of relevance in this group of patients.
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Sanner, Jennifer, Megan L. Grove, Erica Yu, F. Gerard Moeller, Stanley G. Cron, Eric Boerwinkle, Alanna C. Morrison, and Lorraine Frazier. "Effects of Gender-Specific Differences, Inflammatory Response, and Genetic Variation on the Associations Among Depressive Symptoms and the Risk of Major Adverse Coronary Events in Patients With Acute Coronary Syndrome." Biological Research For Nursing 20, no. 2 (January 3, 2018): 168–76. http://dx.doi.org/10.1177/1099800417751662.
Повний текст джерелаАнотація:
Depressive symptoms independently contribute to major adverse coronary events (MACEs), with the biological immune response to depression being a likely mediator of this relationship. To determine whether genetic- and/or gender-specific phenotypic differences contribute to associations among depressive symptoms, inflammatory response, and risk of MACE in patients with acute coronary syndrome (ACS), we conducted a prospective study of 1,117 ACS patients to test a gender-specific model in which depressive symptoms (Beck Depression Inventory-II [BDI-II]) are associated with risk of MACE. Cox proportional hazards models were used to model time to incident MACE and determine whether single-nucleotide polymorphisms (SNPs) in specific inflammatory protein-coding genes and depressive symptoms interact to influence levels of inflammatory proteins or risk of MACE. Females had significantly higher high-sensitivity C-reactive protein and monocyte chemoattractant protein-1 levels. Depression status differed by gender (29.9% of females and 21.1% of males had BDI-II scores indicative of depression [ p = .0014]). Depressive symptoms were associated with MACE; however, the interaction between these symptoms and gender was not significant. SNPs and depressive symptoms did not interact to influence inflammation or MACE. More females than males had BDI-II scores indicative of depression, yet the association between positive depressive symptom status and MACE did not vary by gender. Nor did the SNPs interact with depressive symptoms to influence inflammation or MACE. It remains of interest to identify a high-risk subgroup of ACS patients with genetic polymorphisms that result in immunoinflammatory dysregulation in the presence of depressive symptoms.
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Okun, Alex, Ruth E. K. Stein, Laurie J. Bauman, and Ellen Johnson Silver. "Content Validity of the Psychiatric Symptom Index, CES-Depression Scale, and State-Trait Anxiety Inventory from the Perspective of DSM-IV." Psychological Reports 79, no. 3 (December 1996): 1059–69. http://dx.doi.org/10.2466/pr0.1996.79.3.1059.
Повний текст джерелаАнотація:
We compared the item content of three commonly used scales of psychiatric symptoms [the broad-band Psychiatric Symptom Index (Ilfeld) and two narrow-band scales, the Center for Epidemiologic Studies-Depression Scale (Radloff) and the State-Trait Anxiety Inventory (Spielberger)], with diagnostic criteria and criterion-based symptoms for Major Depressive Episode and Generalized Anxiety Disorder as they appeared in DSM-IV. The Psychiatric Symptom Index and the Center for Epidemiologic Studies—Depression Scale each measured 7 of 9 criterion-based symptoms of Major Depressive Episode. The Psychiatric Symptom Index and State-Trait Anxiety Inventory each measured 5 of 8 domains for Generalized Anxiety Disorder. The Psychiatric Symptom Index had comparable content validity to the narrow-band measures. All met a majority of DSM-IV criteria for depression and anxiety, supporting their applicability for current research.
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Vanheule, Stijn, Mattias Desmet, and Reitske Meganck. "What the Heart Thinks, the Tongue Speaks: A Study on Depression and Lexical Choice." Psychological Reports 104, no. 2 (April 2009): 473–81. http://dx.doi.org/10.2466/pr0.104.2.473-481.
Повний текст джерелаАнотація:
The present study examined symptom-specificity in depression, testing the hypothesis that affective, cognitive, and somatic dimensions in depressive symptoms, as measured with the Beck Depression Inventory–II, cohere, respectively, with the use of affective-, cognitive-, and somatic-related words in natural language, as measured with the Linguistic Inquiry and Word Count. Based on questionnaire and interview data from 32 mental health outpatients, analyses indicate scores for affective depressive symptoms correlate significantly with affective word use, cognitive depressive symptoms are related to cognitively oriented word use combined with affective word use, and the presence of somatic depressive symptoms correlates significantly with words referring to physical states and functions. These results indicate that different facets of depression have specific correlates and that natural word use serves as a psychological marker. From a psychometric point of view, this study substantiates the concurrent validity of the Linguistic Inquiry and Word Count (LIWC2001) categories under study and the Beck Depression Inventory-II subscales for affective, cognitive, and somatic symptoms.
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Eßl-Maurer, Roland, Maria Flamm, Katharina Hösl, Jürgen Osterbrink, and Antje van der Zee-Neuen. "Absenteeism and associated labour costs according to depressive symptom severity in the German general population: why preventive strategies matter." International Archives of Occupational and Environmental Health 95, no. 2 (October 18, 2021): 409–18. http://dx.doi.org/10.1007/s00420-021-01788-7.
Повний текст джерелаАнотація:
Abstract Purpose Depression is a highly prevalent mental health condition with substantial individual, societal and economic consequences. This study focussed on the association of depressive symptom severity with absenteeism duration and employer labour costs. Methods Using cross-sectional data from the German Health Update 2014/2015, multivariable zero-inflated Poisson regression (ZIP) models explored the association of depressive symptom severity (8-item depression patient health questionnaire—PHQ-8), with absenteeism weeks during 12 months in men and women working full- or part-time. The predicted sick leave weeks were multiplied by mean average labour costs. Results The sample consisted of 12,405 persons with an average sick leave of 1.89 weeks (SD 4.26). Fifty-four % were women and 57% were between 40 and 59 years of age. In men and women, mild, moderate, moderately severe and severe depressive symptoms were associated with a significant factor increase in sick leave weeks compared to persons with no or minimal symptoms. Labour costs increased with increasing symptom severity from € 1468.22 for men with no or minimal depressive symptoms to € 7190.25 for men with severe depressive symptoms and from € 1045.82 to € 4306.30 in women, respectively. Conclusion The present results indicate that increasing depressive symptom severity is associated with increasing absenteeism and employer costs. They emphasize the need for implementation, realignment or extension of professional work-site health promotion programmes aiming at the improvement and maintenance of employee health and the reduction of labour costs associated with depression-related sick leave.
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Huh, Hyu Jung, Soon Young Lee, Soo Sang Lee, and Jeong-Ho Chae. "A Network Model of Positive Resources, Temperament, Childhood Trauma, and Comorbid Symptoms for Patient with Depressive Disorders." Psychiatry Investigation 18, no. 3 (March 25, 2021): 214–24. http://dx.doi.org/10.30773/pi.2020.0187.
Повний текст джерелаАнотація:
Objective Temperament, positive resources, childhood trauma, and other clinical comorbid symptoms are related to depressive symptom severity. Here, we used network analysis to examine the interrelations between these clinical factors in patients with depressive disorders.Methods Patients with depressive disorders (n=454) completed self-report questionnaires evaluating clinical symptoms, childhood trauma, temperament, and positive resources. To identify network pattern and the most central aspect, we performed network analysis and centrality analyses. First, we analyzed the network pattern in total participants. Second, we established two groups of those with severe depressive symptoms and those with mild depressive symptoms and compared their network patterns.Results Deficient optimism and depression were the central factors in the network of total participants. In the group with severe depressive symptoms, lack of social support and childhood emotional trauma showed high centrality. Deficient social support and other positive resources played central roles in the group with mild depressive symptoms.Conclusion Network pattern of psychological factors was different between those with mild or severe depression. Lack of positive resources is an important factor in psychological processes in both mild and severe depression. However, childhood emotional trauma may play a relatively important role in patients with severe depressive symptoms.
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Chang, Jae Seung, Yong Min Ahn, Han Young Yu, Hye Jean Park, Kyu Young Lee, Se Hyun Kim, and Yong Sik Kim. "Exploring Clinical Characteristics of Bipolar Depression: Internal Structure of the Bipolar Depression Rating Scale." Australian & New Zealand Journal of Psychiatry 43, no. 9 (January 1, 2009): 830–37. http://dx.doi.org/10.1080/00048670903107666.
Повний текст джерелаАнотація:
Objective: Due to its pleomorphic phenomenology, the clinical features of bipolar depression are difficult to assess. The objective of the present study was therefore to explore the internal structure of the Bipolar Depression Rating Scale (BDRS) in terms of the phenomenological characteristics of bipolar depression. Methods: Sixty patients with DSM-IV bipolar depression completed the BDRS, depression and excitement subscales of the Positive and Negative Syndrome Scale (PANSS-D and PANSS-E), 17-item Hamilton Depression Rating Scale, Montgomery–Äsberg Depression Rating Scale, Young Mania Rating Scale (YMRS), and the Drug-Induced Extrapyramidal Symptoms Scale. The internal structure of the BDRS was explored through hierarchical cluster analysis (HCA) using Ward's method and multidimensional scaling (MDS). Results: From 20-item BDRS data, the HCA yielded two symptom clusters. The first cluster included 12 items of conventional depressive symptoms. The second cluster included eight items of mixed symptoms. The MDS identified a depressive–mixed dimension. The depressive symptom cluster showed a more cohesive and conglomerate cluster structure on the MDS map compared to the mixed symptom cluster. After controlling for the effects of treatment-emergent extrapyramidal symptoms, strong positive correlations were observed between the BDRS and other depression rating scales, and the BDRS also weakly correlated with the YMRS and the PANSS-E. Conclusions: The internal structure of BDRS appears to be sensitive to complex features of bipolar depression. Hence, the BDRS may have an advantage in evaluating clinical changes in patients with bipolar depression within the therapeutic process.
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Scott, B. Patten, V. A. Williams Jeanne, and J. Love Edgar. "Self-Reported Depressive Symptoms in Association with Medication Exposures among Medical Inpatients: A Cross-Sectional Study." Canadian Journal of Psychiatry 40, no. 5 (June 1995): 264–69. http://dx.doi.org/10.1177/070674379504000508.
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Objective To evaluate associations between exposure to three classes of medications (angiotensin converting enzyme inhibitors, calcium channel blockers, and corticosteroids) and self-reported depressive symptoms. Method The study utilised a cross-sectional study design in a sample of medical inpatients. Results Associations between self-reported depressive symptoms and exposure to angiotensin converting enzyme inhibitors or calcium channel blockers were not observed. However, an association between self-reported depressive symptoms and corticosteroid exposure was identified. The association was strongest in subjects reporting apast history of depression or a family history of depression. The strength of the corticosteroid-depressive symptom association was comparable with that of associations observed for age, poverty and psychosocial stress. Conclusions Depressive symptoms among medical inpatients have a biopsychosocial etiology. Corticosteroid exposure may be a biological risk factor for depressive symptoms in this population.
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Costa, Ana Cláudia Maia Mendonça da, Lara Gomes Nery, Gabriela Ramos Ribeiro, Gustavo Silva Oliveira, Rodolfo Lopes Vaz, and Jalsi Tacon Arruda. "Fatores que influenciam a ocorrência do transtorno depressivo em crianças e adolescentes." Research, Society and Development 11, no. 7 (May 19, 2022): e16911729281. http://dx.doi.org/10.33448/rsd-v11i7.29281.
Повний текст джерелаАнотація:
A depressão afeta todas as faixas etárias e vem sendo cada vez mais observada em crianças e adolescentes. Os sintomas mais observados nessa população são a queda do rendimento escolar, tristeza e isolamento, que se intensificam prejudicando o desenvolvimento e contribuindo para a incapacidade humana. Dessa forma, o presente estudo tem como objetivo identificar os principais fatores para a ocorrência do transtorno depressivo infantil, buscando fatores influenciadores, tanto intrínsecos quanto extrínsecos a criança e ao adolescente. Para isso, foi realizada uma revisão integrativa, realizada a partir de dados disponíveis no PubMed, SciELO e Google Acadêmico, utilizando os termos MeSH do PubMed: “Depressive disorder”, “Depressive symptoms”, “Children”, “Adolescents” na qual foram selecionados 23 artigos. Existem diversos fatores de riscos que podem levar a criança e o adolescente a desenvolver o transtorno depressivo. A falta de afeto dos familiares, convivência com um dos pais depressivos, os estressores ambientais, como o abuso sexual e o físico e a perda de um ente querido são alguns desses fatores. Identificar a síndrome depressiva infantil é fundamental devido à necessidade de intervenções, emprego de técnicas de tratamentos e prevenção de problemas posteriores possibilitando assim, uma qualidade de vida maior para esse futuro adulto.
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Bechdolf, Andreas, Frauke Schultze-Lutter, and Joachim Klosterkötter. "Self-experienced vulnerability, prodromal symptoms and coping strategies preceding schizophrenic and depressive relapses." European Psychiatry 17, no. 7 (November 2002): 384–93. http://dx.doi.org/10.1016/s0924-9338(02)00698-3.
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SummaryFor the first time, the present study explores pre-episodic disturbances, i.e. self-experienced vulnerability and prodromal symptoms, and related coping strategies preceding schizophrenic and depressive relapses. After complete recovery from the acute episode, 27 patients with recurrent schizophrenic and 24 patients with recurrent depressive episodes were assessed retrospectively for pre-episodic disturbances and related coping strategies with the “Bonn scale for the assessment of basic symptoms—BSABS”. All (100%) of the schizophrenic and 23 (96%) of the depressive patients showed pre-episodic disturbances. Patients with schizophrenia showed significantly more often an increased emotional reactivity and certain perception and thought disturbances. Depressive patients reported significantly more often an impaired tolerance to certain stress and disorders of emotion and affect. Sixty-three percent of the schizophrenics and 87% of the depressives reacted to pre-episodic disturbances with coping strategies. The pre-episodic disturbances in patients with schizophrenia could be described in terms of mild psychotic productivity, those in depressives in terms of mild depressive syndrome. Future studies will have to show if these findings can be replicated in first episode or initial prodromal state samples and if the assessment of mild psychotic productivity and mild depressive syndrome can be used for early diagnosis and early intervention in schizophrenia and depression.