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Cheng, Shuo, Cunxian Jia, and Yongjie Wang. "Only Children Were Associated with Anxiety and Depressive Symptoms among College Students in China." International Journal of Environmental Research and Public Health 17, no. 11 (June 5, 2020): 4035. http://dx.doi.org/10.3390/ijerph17114035.
Анотація:
This study explored the prevalence of anxiety and depressive symptoms among college students and analyzed the associations between only children and anxiety and depressive symptoms in college students in China. A total of 645 college students, from three universities in Jinan, Shandong, China, were investigated by questionnaire. The self-designed general information questionnaire was used to collect the demographic information such as gender, age, only children or not and so on. The Self-rating Anxiety Scale and Self-rating Depression Scale were used to reflect the psychological state of college students. Binary logistic regression analysis was applied to analyze associated factors of anxiety and depressive symptoms. We have found that there were 25.7% college students with anxiety symptom, 22.2% college students with depressive symptom, and 18.3% college students with a comorbidity of anxiety and depressive symptoms. The prevalence of anxiety symptom, depressive symptom, and comorbidity of anxiety and depressive symptoms in only children was higher than those among non-only children. There were no differences between males and females in anxiety symptom, depressive symptom, and comorbidity of anxiety and depressive symptoms among all college students, only child college students and non-only child college students. Only children were associated with anxiety symptom, depressive symptom, comorbidity of anxiety and depressive symptoms after adjusting potential important confounding factors, such as professional category, grade, parental relationship, parenting style, interpersonal relationship, activity participation enthusiasm, sleeping time, and eating habits. The prevalence of anxiety and depressive symptoms among college students was high. We should pay more attention to the mental health of college students, especially that of only child college students.
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Liu, Tianyin, Wen Zhang, Gloria Hoi-Yan Wong, and Terry Lum. "NETWORK ANALYSIS OF ANXIETY AND DEPRESSIVE SYMPTOMS AMONG OLDER ADULTS WITH DIFFERENTIAL MENTAL HEALTH RISKS." Innovation in Aging 7, Supplement_1 (December 1, 2023): 945. http://dx.doi.org/10.1093/geroni/igad104.3036.
Анотація:
Abstract Anxiety and depressive symptoms are common in older people, and network analysis may provide deeper characterization of symptom-symptom interactions to inform personalized care. The aim of this study was to elucidate characteristics of anxiety and depressive symptom networks of older adults with differential risks for depression and anxiety. A total of 4184 older adults (mean age = 77.3±8.8 years, 3245 women) were recruited from the community. Their anxiety and depressive symptom were measured using the Generalized Anxiety Disorder Scale 7-item (GAD-7) and Patient Health Questionnaire 9-item (PHQ-9), respectively. A cut-off score of 5 was used for both scales to differentiate people with mild or above anxiety/depressive symptoms; by this criterion, 1067 (25.5%) of the sample had no anxiety/depressive symptoms, 1690 (40.4%) had symptoms in one domain, and 1427 (34.1%) had symptoms in both domains. Central symptoms and bridge symptoms were identified via centrality indices and bridge centrality indices, respectively. Network stability was examined using the case-dropping procedure. Overall, Restlessness (GAD-7 item 5), Depressed mood (PHQ-9 item 2), and Fear (GAD-7 item 7) had the highest centrality values; two bridge symptoms, Restlessness and Psychomotor disturbances (PHQ-9 item 8), were also identified. Higher risks for depression and/or anxiety were positively associated with global strength; Restlessness and Depressed mood remained to be central symptoms, but in those with both depression and anxiety risks, Restlessness and Guilt/Self-blame (PHQ-9 item 6) bridged the two domains. Interventions designed to target central symptoms and bridge symptoms may be effective in alleviating co-occurring experiences of anxiety and depression.
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LeMoult, Joelle, Karen Rowa, Martin M. Antony, Susan Chudzik, and Randi E. McCabe. "Effect of Comorbid Depression on Cognitive Behavioural Group Therapy for Social Anxiety Disorder." Behaviour Change 31, no. 1 (February 27, 2014): 53–64. http://dx.doi.org/10.1017/bec.2013.32.
Анотація:
AbstractMany individuals seeking treatment for social anxiety disorder (SAD) also meet criteria for a comorbid depressive disorder. Little is known, however, about how a comorbid depressive disorder affects social anxiety treatment. This study examined 61 participants with SAD and 72 with SAD and a comorbid depressive disorder (SAD+D) before and after 12 weeks of cognitive behavioural group therapy (CBGT) for social anxiety. Although patients with SAD+D reported more severe symptoms of social anxiety and depression at pretreatment, treatment was similarly effective for individuals with SAD and SAD+D. However, individuals with SAD+D continued to report higher symptom severity at post-treatment. Interestingly, CBGT for social anxiety also led to improvements in depressive symptoms despite the fact that depression was not targeted during treatment. Improvement in social anxiety symptoms predicted 26.8% of the variance in improvement in depressive symptoms. Results suggest that depressive symptoms need not be in remission for individuals to benefit from CBGT for social anxiety. However, more than 12 sessions of CBGT may be beneficial for individuals with comorbid depression.
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Spinhoven, Philip, Karin Roelofs, Jacqueline GFM Hovens, Bernet M. Elzinga, Patricia van Oppen, Frans G. Zitman, and Brenda WJH Penninx. "Personality, Life Events and the Course of Anxiety and Depression." European Journal of Personality 25, no. 6 (November 2011): 443–52. http://dx.doi.org/10.1002/per.808.
Анотація:
Using data from the Netherlands Study of Depression and Anxiety, we examined among 1322 participants with a DSM–IV diagnosis of depression or anxiety: (i) whether positive and negative life events influence 1–year course of anxiety and depressive symptoms; (ii) whether personality traits (neuroticism and extraversion) predict symptom course and moderate the impact of life events on symptom course; and (iii) whether life events mediate relationships of neuroticism and extraversion with symptom course. Negative life events were predictive of both anxiety and depressive symptoms, while positive life events predicted the course of depressive symptoms only. Personality traits had significant predictive and moderating effects on symptom course, though these effects were rather small. Copyright © 2011 John Wiley & Sons, Ltd.
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Karsten, Julie, Catharina A. Hartman, Johannes H. Smit, Frans G. Zitman, Aartjan T. F. Beekman, Pim Cuijpers, A. J. Willem van der Does, Johan Ormel, Willem A. Nolen, and Brenda W. J. H. Penninx. "Psychiatric history and subthreshold symptoms as predictors of the occurrence of depressive or anxiety disorder within 2 years." British Journal of Psychiatry 198, no. 3 (March 2011): 206–12. http://dx.doi.org/10.1192/bjp.bp.110.080572.
Анотація:
BackgroundPast episodes of depressive or anxiety disorders and subthreshold symptoms have both been reported to predict the occurrence of depressive or anxiety disorders. It is unclear to what extent the two factors interact or predict these disorders independently.AimsTo examine the extent to which history, subthreshold symptoms and their combination predict the occurrence of depressive (major depressive disorder, dysthymia) or anxiety disorders (social phobia, panic disorder, agoraphobia, generalised anxiety disorder) over a 2-year period.MethodThis was a prospective cohort study with 1167 participants: the Netherlands Study of Depression and Anxiety. Anxiety and depressive disorders were determined with the Composite International Diagnostic Interview, subthreshold symptoms were determined with the Inventory of Depressive Symptomatology–Self Report and the Beck Anxiety Inventory.ResultsOccurrence of depressive disorder was best predicted by a combination of a history of depression and subthreshold symptoms, followed by either one alone. Occurrence of anxiety disorder was best predicted by both a combination of a history of anxiety disorder and subthreshold symptoms and a combination of a history of depression and subthreshold symptoms, followed by any subthreshold symptoms or a history of any disorder alone.ConclusionsA history and subthreshold symptoms independently predicted the subsequent occurrence of depressive or anxiety disorder. Together these two characteristics provide reasonable discriminative value. Whereas anxiety predicted the occurrence of an anxiety disorder only, depression predicted the occurrence of both depressive and anxiety disorders.
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Kouros, Chrystyna D., Susanna Quasem, and Judy Garber. "Dynamic temporal relations between anxious and depressive symptoms across adolescence." Development and Psychopathology 25, no. 3 (July 23, 2013): 683–97. http://dx.doi.org/10.1017/s0954579413000102.
Анотація:
AbstractSymptoms of anxiety and depression are prevalent among adolescents and associated with impairment in multiple domains of functioning. Moreover, anxiety and depression frequently co-occur, with estimated comorbidity rates as high as 75%. Whereas previous research has shown that anxiety symptoms predict increased depressive symptoms over time, the relation between depressive symptoms and later anxiety symptoms has been inconsistent. The present study examined dynamic relations between anxiety and depressive symptoms across adolescence and explored whether these longitudinal relations were moderated by maternal history of anxiety, family relationship quality, or children's attributional style. Participants included 240 children (M age = 11.86 years; 53.9% female) and their mothers, who were assessed annually for 6 years. Children reported on their depressive symptoms and mothers reported on their child's anxiety symptoms. Dynamic latent change score models indicated that anxiety symptoms predicted subsequent elevations in depressive symptoms over time. Depressive symptoms predicted subsequent elevations in anxiety symptoms among children who had mothers with a history of anxiety, reported low family relationship quality, or had high levels of negative attributions. Thus, whereas anxiety symptoms were a robust predictor of later depressive symptoms during adolescence, contextual and individual factors may be important to consider when examining relations between depressive symptoms and subsequent change in anxiety symptoms.
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Sharovsky, Lilian Lopes, and Bellkiss Wilma Romano. "Depressive and anxiety symptoms in patients with Metabolic Syndrome." Estudos de Psicologia (Campinas) 30, no. 4 (December 2013): 603–8. http://dx.doi.org/10.1590/s0103-166x2013000400013.
Анотація:
Depressive symptoms have been associated to the Metabolic Syndrome. Nevertheless, only a few studies have evaluated anxiety and depression concomitantly. The objective of the research was to evaluate the intensity of depressive and anxiety symptoms in patients with Metabolic Syndrome and their relation to demographic variables. A unicenter, transversal study was carried out. A social demographic questionnaire was used. Depressive symptoms were measured with Beck Depression Inventory and anxiety symptoms were measured with Hamilton Anxiety Scale Rate. A total of 103 ambulatory patients, 60 of them men, with mean age 55.4 years (±7,6) with a diagnosis of Metabolic Syndrome were included in the study. Anxiety symptoms of very severe intensity were present in 51.5% (n=53) while severe depressive symptoms in only 5.8% (n=6). Anxiety and depressive symptoms were significantly associated. In this sample, anxiety predominated in relation to the depressive symptoms. The anxiety symptoms were more intense in women and that had low level of education.
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CHEN, J. H., A. J. BIERHALS, H. G. PRIGERSON, S. V. KASL, C. M. MAZURE, and S. JACOBS. "Gender differences in the effects of bereavement-related psychological distress in health outcomes." Psychological Medicine 29, no. 2 (March 1999): 367–80. http://dx.doi.org/10.1017/s0033291798008137.
Анотація:
Background. This study examined whether traumatic grief, depressive and anxiety symptoms formed three distinct factors for widows and widowers. In addition, we examined whether high symptom levels of traumatic grief, depression and anxiety predicted different mental and physical health outcomes for widows and widowers.Method. Ninety-two future widows and 58 future widowers were interviewed at the time of their spouse's hospital admission and then at 6 weeks, 6, 13 and 25 month follow-ups. Principal axis factor analyses tested the distinctiveness of traumatic grief, depressive and anxiety symptoms, by gender. Repeated measures ANOVA tested for gender differences and changes over time in mean symptom levels of traumatic grief, depression and anxiety. Linear and logistic regression models estimated the effects of high symptom levels of traumatic grief, depression and anxiety at 6 months on health outcomes at 13 and 25 months post-intake by gender.Results. Three distinct symptom clusters (i.e. traumatic grief, depressive and anxiety symptoms) were found to emerge for both widows and widowers. Widows had higher mean levels of traumatic grief, depressive and anxiety symptoms. High symptom levels of traumatic grief measured at 6 months predicted a physical health event (e.g. cancer, heart attack) at 25 months post-intake for widows. High symptom levels of anxiety measured at 6 months predicted suicidal ideation at 25 months for widowers.Conclusions. The results suggest that there are gender differences in the levels of psychological symptoms resulting from bereavement and in their effects on subsequent mental and physical health for widows and widowers.
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Okun, Alex, Ruth E. K. Stein, Laurie J. Bauman, and Ellen Johnson Silver. "Content Validity of the Psychiatric Symptom Index, CES-Depression Scale, and State-Trait Anxiety Inventory from the Perspective of DSM-IV." Psychological Reports 79, no. 3 (December 1996): 1059–69. http://dx.doi.org/10.2466/pr0.1996.79.3.1059.
Анотація:
We compared the item content of three commonly used scales of psychiatric symptoms [the broad-band Psychiatric Symptom Index (Ilfeld) and two narrow-band scales, the Center for Epidemiologic Studies-Depression Scale (Radloff) and the State-Trait Anxiety Inventory (Spielberger)], with diagnostic criteria and criterion-based symptoms for Major Depressive Episode and Generalized Anxiety Disorder as they appeared in DSM-IV. The Psychiatric Symptom Index and the Center for Epidemiologic Studies—Depression Scale each measured 7 of 9 criterion-based symptoms of Major Depressive Episode. The Psychiatric Symptom Index and State-Trait Anxiety Inventory each measured 5 of 8 domains for Generalized Anxiety Disorder. The Psychiatric Symptom Index had comparable content validity to the narrow-band measures. All met a majority of DSM-IV criteria for depression and anxiety, supporting their applicability for current research.
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França, Alex Bacadini, Adam Lee Gordon, Rajvinder Samra, Evelise Saia Rodolpho Duarte, and Alessandro Ferrari Jacinto. "Symptoms of mood disorders in family carers of older people with dementia who experience caregiver burden: a network approach." Age and Ageing 49, no. 4 (February 24, 2020): 628–33. http://dx.doi.org/10.1093/ageing/afaa008.
Анотація:
Abstract Background informal carers of people with dementia are at greater risk of anxiety and depressive disorders if they find caregiving to be a burden. The aim of this study was to use a network analysis of cross-sectional data to investigate the relationships between anxiety and depressive symptoms in family carers of older people with dementia who experience burden. Methods sixty family carers exhibiting high levels of burden using the Zarit Burden Interview were included in the study. Participants completed the Hospital Anxiety and Depression Scale. The network analysis identified the depression and anxiety symptom network using features including a topological graph, network centrality metrics and community analysis. The network was estimated through the graphical LASSO technique in combination with a walktrap algorithm to obtain the clusters within the network and the connections between the nodes (symptoms). A directed acyclic graph was generated to model symptom interactions. Results the resulting network architecture shows important bridges between depression and anxiety symptoms. Lack of pleasure and loss of enjoyment were identified as potential gateway symptoms to other anxiety and depression symptoms and represent possible therapeutic targets for psychosocial interventions. Fear and loss of optimism were highly central symptoms, indicating their importance as warning signs of more generalised anxiety and depression. Conclusions this network analysis of depressive and anxiety symptoms in overburdened family carers provides important insights as to what symptoms may be the most important targets for behavioural interventions.
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McMahon, Grace E., Peter J. Anderson, Rebecca Giallo, Carmen C. Pace, Jeanie L. Cheong, Lex W. Doyle, Alicia J. Spittle, Megan M. Spencer-Smith, and Karli Treyvaud. "Mental Health Trajectories of Fathers Following Very Preterm Birth: Associations With Parenting." Journal of Pediatric Psychology 45, no. 7 (June 9, 2020): 725–35. http://dx.doi.org/10.1093/jpepsy/jsaa041.
Анотація:
Abstract Objective Mothers of infants born very preterm (VPT) are at high risk of mental health difficulties. However, less is known about the course of fathers’ depressive and anxiety symptoms over time, and the implications this may have for early parenting behaviors. Methods In total, 100 fathers of 125 infants born VPT (<30 weeks’ gestation) completed questionnaires assessing depressive and anxiety symptoms shortly after their infant’s birth, and when their infant reached term-equivalent age, 3 months, 6 months, and 12 months’ corrected age. At 12 months’ corrected age, fathers’ parenting behaviors were assessed using the Emotional Availability Scales. Longitudinal latent class analysis was used to identify trajectories of fathers’ depressive and anxiety symptoms, and linear regression equations examined relationships between these trajectories and fathers’ parenting behaviors. Results For both depressive and anxiety symptoms, two distinct trajectories were identified. For depression, most fathers were assigned to the persistently low symptom trajectory (82%), while the remainder were assigned to the persistently high symptom trajectory (18%). For anxiety, 49% of fathers were assigned to the persistently low symptom trajectory, while 51% were assigned to the trajectory characterized by moderate symptoms over the first postnatal year. There were no significant differences in parenting behaviors between fathers assigned to the different depressive and anxiety symptom trajectories. Conclusions Fathers of infants born VPT are at risk of chronic depressive and anxiety symptoms over the first postnatal year, highlighting the need for screening and ongoing support.
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Mcinerney, A., N. Lindekilde, A. Nouwen, N. Schmitz, and S. Deschenes. "Symptoms of diabetes distress, depression, and anxiety in people with type 2 diabetes: identifying central and bridge symptoms using network analysis." European Psychiatry 65, S1 (June 2022): S288. http://dx.doi.org/10.1192/j.eurpsy.2022.736.
Анотація:
Introduction People with diabetes are vulnerable to diabetes-related distress and are more likely to experience depressive and anxiety symptoms than the general population. Diabetes distress, depressive, and anxiety symptoms also tend to commonly co-occur. Objectives This study aimed to apply network analysis to explore the associations between diabetes distress, depressive, and anxiety symptoms in a cohort of adults with type 2 diabetes. Methods Data were from the baseline (2011) assessment of the Evaluation of Diabetes Insulin Treatment (EDIT) study (N = 1,796; 49% female; mean age = 60, SD = 8) from Quebec, Canada. A first network using the 17 items of the diabetes distress scale (DDS-17) was estimated. A second network was estimated using the 17 items of the DDS-17, the 9 depressive items of the PHQ-9, and the 7 anxiety items of the GAD-7. Symptom centrality, network stability, and bridge symptoms were examined. Results Regimen-related and physician-related distress symptoms were amongst the most central (highly connected) in the diabetes distress network. Worrying too much (anxiety), Not feeling motivated to keep up diabetes self-management (diabetes distress), and Feeling like a failure (depression) were the most central symptoms in the combined network. Feeling like a failure (depression) was highly connected to diabetes distress symptoms, representing a potential bridge between diabetes distress and depression. Conclusions Identifying central and bridge symptoms may provide new insights into diabetes distress, depressive, and anxiety symptom maintenance and comorbidity in people with type 2 diabetes. Disclosure No significant relationships.
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Washington, Jasmine, Nia Milligan, and Janeese Brownlow. "0963 An Investigation of Sleep Disturbance, Depression, and Anxiety Among Emerging Adults." SLEEP 47, Supplement_1 (April 20, 2024): A413. http://dx.doi.org/10.1093/sleep/zsae067.0963.
Анотація:
Abstract Introduction Sleep disturbances are highly comorbid with psychiatric disorders. Data indicates high comorbidity rates between insomnia and depression and anxiety disorders. However, limited data exist regarding whether sleep disturbance is an independent risk factor for or outcome of psychiatric disorders among emerging adults. This study explored relationships between insomnia, depression, and generalized anxiety. Methods Data were obtained from emerging adults (N=105; Mean age=20.28 (SD=1.9); 81% Female) who completed self-report measures. The Beck depression inventory (BDI-II) assessed for the presence and intensity of overall depressive symptoms. A cutoff score of greater than 20 was derived to determine probable depression. The Generalized Anxiety Disorder (GAD-7) scale assessed for severity and diagnosis of GAD. A cutoff score of 10 or greater was used to determine probable GAD. The Insomnia Severity Index assessed for the nature, severity, and impact of insomnia symptoms, with higher scores indicating greater symptom severity. All statistical analyses were conducted using IBM SPSS version 29. Results Approximately 36.2% of the sample had probable depression and 37.1% of the sample had probable generalized anxiety disorder. Data showed significant correlations between insomnia severity and probable depression (rpb=.316 p<.001) and generalized anxiety disorder (rpb=.449, p<.001), respectively. Linear regressions indicated that depressive symptoms (R2=.266, p<.001) and generalized anxiety symptoms (R2=.301, p<.001) were significant predictors for insomnia severity, respectively. Data also showed that insomnia severity significantly predicted depressive and generalized anxiety symptoms (R2=.355, p<.001), with insomnia being a stronger predictor for generalized anxiety symptoms (β=.374, p<.001) than depressive symptoms (β=.291, p=.004). Logistic regressions indicated that insomnia severity increased the odds of having both probable depression (X2=9.54, OR=1.14, p=.002) and generalized anxiety disorder (X2=17.30, OR=1.23, p<.001). Conclusion Findings suggest that insomnia severity is a risk factor for both depressive and generalized anxiety symptom severity and probable diagnoses. Data also indicated that depressive and generalized anxiety symptoms were independent risk factors for insomnia severity. Given the results, longitudinal studies are needed to understand whether there is a bidirectional relationship between sleep disturbance, depression, and generalized anxiety among emerging adults. Support (if any) This study was funded by a Center Grant from the National Institutes of General Medical Sciences (Grant # P20GM103653).
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Luo, Xiaomin, Yu Zhou, Ruimin Zheng, Xin Li, Yue Dai, Anuradha Narayan, Xiaona Huang, et al. "Association of health-risk behaviors and depressive symptoms and anxiety symptoms: a school-based sample of Chinese adolescents." Journal of Public Health 42, no. 3 (October 22, 2019): e189-e198. http://dx.doi.org/10.1093/pubmed/fdz115.
Анотація:
Abstract Background Depressive symptoms and anxiety symptoms of adolescents not only affect youth but also have wide-ranging impacts on the health of adults. The study was carried out to determine the epidemiological characteristics of depressive symptoms and anxiety symptoms and the associations between the two and health-risk behaviors in Chinese adolescents. Methods Participants were recruited from the junior and senior high schools in China. Data were collected by self-designed questionnaires. The questionnaires included questions about demographic characteristics, depressive symptom scales, anxiety symptom scales and nine categories of health-risk behaviors. Descriptive analysis and binary logistic regression were performed by SPSS 21.0 software. Results There were 4.4% of the participants with depressive symptoms. Approximately 32.0% of the participants had anxiety symptoms. Girls and general senior school students were risk factors for depressive symptoms and anxiety symptoms. Multiple health-risk behaviors were associated with depressive symptoms and anxiety symptoms in Chinese adolescents. Conclusion Depressive symptoms and anxiety symptoms were prevalent in Chinese adolescents. Their distribution was affected by certain health-risk behaviors. Multiple health-risk behaviors were associated with depressive symptoms and anxiety symptoms in Chinese adolescents.
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Zimmerman, Mark, Caroline Balling, Iwona Chelminski, and Kristy Dalrymple. "Understanding the severity of depression: do nondepressive symptoms influence global ratings of depression severity?" CNS Spectrums 25, no. 4 (November 12, 2019): 557–60. http://dx.doi.org/10.1017/s1092852919001548.
Анотація:
AbstractObjective.Almost all depression measures have been developed without discussing how to best conceptualize and assess the severity of depression. It is therefore not surprising that measures differ in both how items are rated and item content. The question that we address in the present report from the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project is whether a measure of depression severity should include symptoms that are frequent in depressed patients but are defining features of other disorders (eg, anxiety, irritability)Methods.Patients were evaluated with a semi-structured interview and severity ratings were made of each symptom of major depressive disorder (MDD) as well as anxiety, irritability, and somatization. Patients were also rated on the Clinical Global Index of severity (CGI).Results.Three of the 5 nondepressive symptoms (psychic anxiety, somatic anxiety, and subjective anger) were significantly correlated with the CGI. The correlation between the sum of all 5 nondepressive symptoms and the CGI was significantly lower than the correlation between the sum of the depressive symptom severity ratings (0.12 vs 0.52, z = 11.0, p < .001). The partial correlation between the CGI and the nondepressive symptom severity ratings (after controlling for the total depressive symptom ratings) was nonsignificant.Discussion.After accounting for the severity of depressive symptoms, the severity of the nondepressive symptoms was not associated with global ratings of depressive severity. These findings raise questions regarding the appropriateness of including ratings of anxiety, irritability, and somatization on a measure that purportedly assesses the severity of depression.
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Honeycutt, Lucy, Jean-François Gagnon, Amélie Pelletier, Jacques Y. Montplaisir, Geneviève Gagnon, and Ronald B. Postuma. "Characterization of Depressive and Anxiety Symptoms in Idiopathic REM Sleep Behavior Disorder." Journal of Parkinson's Disease 11, no. 3 (August 2, 2021): 1409–16. http://dx.doi.org/10.3233/jpd-212625.
Анотація:
Background: Depression and anxiety are common in synucleinopathies and often present during prodromal stages, including idiopathic/isolated REM sleep behavior disorder (iRBD). However, the specific profiles of depression/anxiety and their predictive values for phenoconversion remain unclear. Objective: To assess the predominant manifestations, predictive value, and changes over time in depressive and anxiety symptoms in iRBD. Methods: Patients with polysomnography-confirmed iRBD (n = 114) and healthy controls (n = 44) were recruited. The Beck Depression Inventory and Beck Anxiety Inventory were administered at baseline, which was repeated prospectively over follow-up. Factor solutions were generated to delineate symptom clusters within the scales, and to help disentangle primary mood symptoms from other neurodegenerative confounds. Total scores, individual scale items, and factors were evaluated to 1) compare patients and controls, 2) assess progression of symptoms over time, and 3) assess predictive value for phenoconversion. Results: At baseline, iRBD patients had more severe depressive (9.0 = 6.7 vs 5.8 = 4.8) and anxiety (7.0 = 7.9 vs 4.5 = 6.0) symptoms than controls. Increased scores were seen in numerous individual scale items and most scales’ factors. For depressive symptoms, there was no progression of total scores or factors over time. However, anxiety scores worsened slightly over prospective follow-up (annual slope = 0.58 points, p < 0.05). Over an average 2.4 = 3.1-year follow-up, 37 patients phenoconverted and 72 remained disease-free. Neither baseline depressive nor anxiety symptoms predicted phenoconversion to clinical neurodegenerative disease. Conclusions: Depressive and anxiety symptoms are common in iRBD. However, they do not predict phenoconversion and show only modest progression over time, solely for anxiety.
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Zhai, Yusen, Mahmood Almaawali, and Xue Du. "The Moderating Role of Anxiety and Depressive Symptoms in Protective Effects of Health Behaviors among Clients Using Mental Health Services." Journal of Clinical Medicine 13, no. 6 (March 18, 2024): 1753. http://dx.doi.org/10.3390/jcm13061753.
Анотація:
College-student clients using mental health services contend with increased anxiety and depressive symptoms, and their vulnerability to infectious respiratory diseases and severe clinical outcomes rises. To mitigate severe outcomes, health behaviors serve as essential protective tools to reduce the risk of infectious diseases, including COVID-19. Considering the escalating prevalence of anxiety and depression among college-student clients, little is known about how anxiety and depressive symptoms could potentially attenuate the protective effects of COVID-19 health behaviors (i.e., masking, social distancing, and hygiene practice). This study aims to examine the interactive effects of anxiety/depression and health behaviors in predicting COVID-19 infection. Methods: We analyzed data from the 2020–2021 Healthy Mind Study including a random sample of 9884 college-student clients in mental health services across 140 higher education institutions in the United States. We performed multivariable logistic regression to assess whether and to what extent the associations between COVID-19 health behaviors and infection depended on severity of anxiety or depressive symptoms. Results: Anxiety symptom severity negatively moderated the protective effects of social distancing against infection after adjusting for demographic characteristics and pre-existing chronic health conditions. Depressive symptom severity negatively moderated the protective effects of masking, social distancing, or hygiene practices against infection. Conclusion: The associations between certain COVID-19 health behaviors and infection were conditional on anxiety and depressive symptom severity. Findings suggest a potential public health benefit of mental health clinicians’ efforts in assessing and treating clients’ anxiety and depressive symptoms, namely reducing their vulnerability to COVID-19 infection and perhaps other infectious respiratory diseases.
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Masuya, Jiro, Chihiro Morishita, Motoki Higashiyama, Ayaka Deguchi, Yoshitaka Ishii, Miki Ono, Mina Honyashiki, Yoshio Iwata, and Takeshi Inoue. "Depressive rumination and trait anxiety mediate the effects of childhood victimization on adulthood depressive symptoms in adult volunteers." PLOS ONE 18, no. 5 (May 23, 2023): e0286126. http://dx.doi.org/10.1371/journal.pone.0286126.
Анотація:
Background Prior studies have reported that childhood victimization experiences substantially augment the risk of depression and suicide in adulthood. Several of our previous studies suggested that childhood experiences of victimization interact with the quality of parenting experienced in childhood, childhood experiences of abuse, neuroticism, and other factors to influence depressive symptoms in adulthood. In this study, it was hypothesized that “childhood victimization” worsens “trait anxiety” and “depressive rumination”, and that “trait anxiety” and “depressive rumination” are mediators that worsen “depressive symptoms in adulthood”. Subjects and methods The following self-administered questionnaires were completed by 576 adult volunteers: Patient Health Questionnaire-9, State–Trait Anxiety Inventory form Y, Ruminative Responses Scale, and Childhood Victimization Rating Scale. Statistical analyses were performed by Pearson correlation coefficient analysis, t-test, multiple regression analysis, path analysis, and covariance structure analysis. Results Path analysis demonstrated that the direct effect was statistically significant for the paths from childhood victimization to trait anxiety, depressive rumination, and depressive symptom severity. Moreover, the indirect effect of childhood victimization on depressive rumination mediated by trait anxiety was statistically significant. The indirect effects of childhood victimization on depressive symptom severity mediated by trait anxiety and depressive rumination were statistically significant. Furthermore, the indirect effect of childhood victimization on depressive symptom severity mediated by both trait anxiety and depressive rumination was statistically significant. Conclusions We found that childhood victimization directly and adversely influenced each of the above factors, and indirectly worsened adulthood depressive symptoms with trait anxiety and depressive ruminations as mediating factors. The present study is the first to clarify these mediation effects. Therefore, the results of this study suggest the importance of preventing childhood victimization and the importance of identifying and addressing childhood victimization in patients with clinical depression.
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Kornetov, N., O. Yarosh, and E. Sitnikova. "Depressive and anxiety disorders among women with obesity." European Psychiatry 64, S1 (April 2021): S339. http://dx.doi.org/10.1192/j.eurpsy.2021.909.
Анотація:
IntroductionAbdominal obesity is currently a growing problem in public health and has a high comorbidity with depressive and anxiety disorders. Obesity significantly decreases life quality, causes disability and decreases life expectancy.ObjectivesThe objective of this study was to examine anxiety and depressive symptoms among women, who received individual or group psychotherapy sessions due to obesity control.Methods577 women aging from 18 to 65 were examined. Height and weight were measured, Body mass index (BDI) was calculated based on received data. Depressive symptoms were determined with the PHQ-9 questionnaire [Kroenke K, Spitzer RL, Williams JB]. Anxiety symptoms were determined with the GAD-7 questionnaire. The level of social adaptation was examined.ResultsThe prevalence of mild depression in our sample of women with obesity was 31.5%, 19.1% - moderate depression, 1% - severe depression, 48.4% had no depression symptoms. Anxiety symptoms were found in 38.2% of examined women, 61.8% showed no anxiety symptoms. Furthermore, when patients were divided into subgroups accordingly to BMI, anxiety was mostly registered among ones with normal BMI. An average correlation between indicators of anxiety and depressive symptoms was identified (r=0,62, p<0,05). Average correlation between indicators of anxiety and depression and the level of social adaptation (r=0,59 and r=0,48 relatively, p<0,05). Anxiety and depressive symptoms’ dependency on BMI was not established.ConclusionsThe received data showed that anxiety and depression have high prevalence among women with obesity. The study will help medical specialists draw attention to high comorbidity between abdominal obesity and anxiety-depressive disorders.
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Cheng, Ching-Yu, Yu-Hua Chou, Chia-Hao Chang, and Shwu-Ru Liou. "Trends of Perinatal Stress, Anxiety, and Depression and Their Prediction on Postpartum Depression." International Journal of Environmental Research and Public Health 18, no. 17 (September 3, 2021): 9307. http://dx.doi.org/10.3390/ijerph18179307.
Анотація:
Perinatal stress, anxiety, and depression impacts not only women but also their child(ren). The purpose of this longitudinal study is to explore trends of stress, anxiety, and depressive symptoms from pregnancy to postpartum and understand predictions of stress and anxiety on postpartum depression. One-hundred-fifty-six women at 23–28 weeks gestation (T1), 147 at 32–36 weeks gestation (T2), 129 at over 36 weeks gestation (T3), and 83 at postpartum (T4) completed study surveys. The Perceived Stress Scale, Center for Epidemiologic Studies Depression scale, and State-Trait Anxiety Inventory were used to measure stress, depressive symptoms, and anxiety. Descriptive statistics, Pearson and Spearman’s correlation, and Generalized Estimating Equation were applied to analyze the data. Results showed that levels of anxiety and depressive symptoms increased from 24 weeks gestation to postpartum, whereas stress levels decreased during pregnancy but increased in postpartum. Over half of women experienced anxiety symptoms, especially during late pregnancy and postpartum. Stress, anxiety, and depressive symptoms were inter-correlated. Notably, women at late pregnancy and postpartum were prone to stress, anxiety, and depression. Prenatal anxiety could predict postpartum depressive symptoms. Active assessment and management of stress, anxiety, and depression is needed and should begin from early pregnancy and continue until postpartum.
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Mohamed Saini, Suriati, Susan Tan Mooi Koon, Mohamad Adam Bujang, Gerard Lim Chin Chye, Shalisah Sharip, Suzaily Wahab, Nik Ruzyanei Nik Jaafar, Chan Lai Fong, and Azlin Baharudin. "Effect of Anxiety and Depression on Survival of Cancer Patients, a 13 Year Follow-up." Asian Pacific Journal of Cancer Care 6, no. 1 (March 26, 2021): 9–13. http://dx.doi.org/10.31557/apjcc.2021.6.1.9-13.
Анотація:
Introduction: Anxiety and depression occur at a high rate in cancer patients. However, debate remains regarding the effect of anxiety and depression on cancer survival. Objective: This study aimed to determine the effect of anxiety and depressive symptoms on the survival of cancer patients. Methods: The subjects consisted of 112 cancer patients who attended the Oncology and Radiotherapy outpatient clinic Hospital Kuala Lumpur, Malaysia, in 1999. Anxiety and depressive symptoms were measured using the Hospital Anxiety and Depression Scale (HADS) questionnaire at inception. Information on patients’ mortality status for extended 13 years follow-up (in 2011) was obtained from the National Registration Department death records. Overall survival for each anxiety and depressive symptoms scores in HADS at 13 years was calculated using Cox proportional hazards regression analysis. Results: Cancer patients experienced more anxiety (83%) compared to depressive symptoms (40.2%). The mean (S.D.) HADS scores for depressive symptoms were 9.9 (2.5), and the anxiety symptoms score was 12.6 (2.1). At 13 years, half of the patients (50.9%) had died. No significant effect of anxiety (p=0.399, 95% C.I.= 6.2-8.4) or depressive symptoms at inception (p=0.749, 95% C.I.= 5.9-8.4) towards cancer patients’ survival was found at 13 years follow-up. Conclusion: The occurrence of anxiety symptoms among cancer patients in this study was 2-folds higher than depressive symptoms. However, no significant increased risk of death was found in cancer patients with anxiety or depressive symptoms at 13 years follow-up. It may imply that as time extended, survival in cancer patients may be related to various interacting elements, and intervening health factors are of importance.
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Brown, Hannah M., Richard Meiser-Stedman, Harriet Woods, and Kathryn J. Lester. "Cognitive Vulnerabilities for Depression and Anxiety in Childhood: Specificity of Anxiety Sensitivity and Rumination." Behavioural and Cognitive Psychotherapy 44, no. 1 (November 11, 2014): 30–42. http://dx.doi.org/10.1017/s1352465814000472.
Анотація:
Background: Childhood anxiety and depression frequently co-occur. Exploring specificity in cognitive processes for anxiety and depression in childhood can provide insight into cognitive vulnerabilities contributing to the development of anxiety and depressive disorders and inform targeted psychological interventions. Anxiety sensitivity and rumination are robust cognitive vulnerabilities for anxiety and depression, respectively. However, despite conceptual similarities, they are rarely considered together within a single study. Aims: The current study explored specific and shared associations between anxiety sensitivity subscales and rumination and anxiety and depressive symptoms in unselected children. Method: Multiple regression analyses explored to what extent specific self-reported anxiety sensitivity subscales (physical, social and mental concerns) and rumination predicted anxiety and depressive symptoms in 147 unselected children, aged 7–11 years. Results: Physical and social concern subscales of anxiety sensitivity were specifically associated with anxiety, whilst rumination was specifically associated with depressive symptoms. The mental concerns subscale of anxiety sensitivity was independently associated with both anxiety and depressive symptoms. These associations were only partially mediated by rumination. Conclusions: Anxiety and depression in young people are characterized by specific and shared cognitions. Evidence for shared and specific associations between the cognitive vulnerabilities of anxiety sensitivity and rumination, and anxiety and depression highlight the utility of transdiagnostic research and confirm that cognitive therapies may benefit from targeting cognitive concerns relating specifically to the patient's presenting symptoms.
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Brombach, Ruth, Jessica Dietch, John Sy, Tracy Trevorrow, and Eric Zhou. "0626 Type of screen time and the relationship between anxiety, depressive and insomnia symptoms in college students." SLEEP 46, Supplement_1 (May 1, 2023): A275. http://dx.doi.org/10.1093/sleep/zsad077.0626.
Анотація:
Abstract Introduction Limited and conflicting evidence examines associations between screen time, depression, anxiety and insomnia in adolescents. Surprisingly few studies focus on college students who face unique sleep-related challenges, frequent media use and elevated rates of mental health problems. Therefore, the goal of the present study was to examine the influence of different types of screen time on the relationship between anxiety/depressive symptoms and insomnia symptoms in college students. Methods Participants (N = 1,085 college students with a mean age of M = 21.15 [SD = 5.51]) completed questionnaires of demographics, anxiety, depression, insomnia, and daily screen time. Type of screen time was classified as: (1) social, (2) non-social, or (3) productivity. We conducted correlations and used Model 1 of the PROCESS macro version 3.5 was used to determine whether type of screen time moderated the relationship between depressive or anxiety symptoms and insomnia. Results Insomnia symptoms were moderately correlated with anxiety (r = .49, p = <.001) and depressive symptoms (r = .60, p = <.001). Anxiety symptoms were correlated with social screen time (r = .09, p = <.01); depressive symptoms were correlated with non-social screen time (r = .13, p = <.001). Social screen time moderated the relationship between anxiety symptoms and insomnia symptoms (b = -.03, SE = .01, p = .01) and the relationship between depressive symptoms and insomnia symptoms (b = -.02, SE = .01, p = .02). Productivity and non-social screen time were not significant moderators. Conclusion Anxiety symptoms were only correlated with social screen time whereas depressive symptoms were only correlated with using non-social screen time. Moderation analyses revealed social screen time moderated the relationship between anxiety/depressive symptoms and insomnia symptoms. Elevated social screen time was associated with elevated insomnia symptoms among participants with less anxiety/depressive symptoms. Distinguishing between non-social and social screen time may be relevant when examining the influence of screen time on depressive/anxiety symptoms and their relationship with insomnia symptoms. Further research could address these findings in a clinical sample and examine whether intervening on specific types of screen time impacts the relationship between depression/anxiety and insomnia. Support (if any) None
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Rothenbacher, Dietrich, Harry Hahmann, Bernd Wüsten, Wolfgang Koenig, and Hermann Brenner. "Symptoms of anxiety and depression in patients with stable coronary heart disease: prognostic value and consideration of pathogenetic links." European Journal of Cardiovascular Prevention & Rehabilitation 14, no. 4 (August 2007): 547–54. http://dx.doi.org/10.1097/hjr.0b013e3280142a02.
Анотація:
Background We evaluated the association of symptoms of anxiety and depression with fatal and non-fatal cardiovascular disease events among patients with coronary heart disease and considered several potential underlying pathogenetic links. Design This was a prospective cohort study. Methods In this study, including coronary heart disease patients undergoing an in-patient rehabilitation program, symptoms of anxiety and depression were evaluated with the Hospital Anxiety and Depression Scale (HADS). Fatal and non-fatal cardiovascular disease events were determined during a 3-year follow-up. Results Of the 1052 patients with CHD 16.1% showed a borderline and 8.3% a manifest anxiety symptoms score, whereas 11.8 and 5.9% showed a borderline and manifest depressive symptoms score, respectively. During the 3-year follow-up fatal and non-fatal cardiovascular disease events were observed in 73 (6.9%) patients. After adjustment for covariates, patients having manifest anxiety symptoms had a statistically significant hazard ratio (HR) of 2.32 [95% confidence interval (CI) 1.14-4.74] for a cardiovascular disease event, and patients with depressive symptoms had an HR of 1.47 (95% CI 0.62-3.51) compared to other patients. In a model considering anxiety and depressive symptom scores simultaneously, the hazard ratio for a cardiovascular disease event associated with anxiety symptoms increased to 3.31 (95% CI 1.32-8.27), whereas the hazard ratio associated with depressive symptoms decreased (HR 0.62; 95% CI 0.20-1.87). We found a positive association of increased anxiety scores with body mass index and systolic blood pressure. Conclusions The study suggests an important role especially for symptoms of anxiety for long-term prognosis of patients with known coronary heart disease. It furthermore suggests that several pathogenetic links may partly explain the increased risk.
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Ayano, G., K. Betts, R. Tait, B. Dachew, A. Lin, and R. Alati. "The risk of attention deficit hyperactivity disorder symptoms in the adolescent offspring of mothers with anxiety and depressive symptoms. Findings from the raine study." European Psychiatry 64, S1 (April 2021): S88. http://dx.doi.org/10.1192/j.eurpsy.2021.261.
Анотація:
IntroductionWhile there exist some studies that explored the association between maternal anxiety and depressive symptoms and the risk of attention-deficit/hyperactivity disorder (ADHD) in early and late childhood, studies exploring the risk in late adolescence are however lacking.ObjectivesThis is the first study that aimed to investigate the association between maternal anxiety, depressive, as well as comorbid anxiety and depressive symptoms, and the risk of ADHD symptoms in late adolescence.MethodsWe used data from the Raine Study, a birth cohort in Western Australia. The Depression, Anxiety, and Stress Scale (DASS) was used to assess maternal depressive and anxiety symptoms when the child was aged 10. Whereas, the DSM-oriented scales of the child behavior checklist (CBCL) was used to assess ADHD symptoms offspring in adolescents aged 17. Log-binomial regression model was used to explore the associations.ResultsAfter adjusting for relevant covariates, we found an increased risk of ADHD symptoms in the adolescent children of mothers with anxiety [RR 2.84 (95%CI 1.18-6.83)] as well as comorbid anxiety and depressive symptoms [RR 5.60 (95%CI 3.02-10.37)]. No association was seen with maternal depressive symptoms.ConclusionsThis study suggested that adolescent offspring of mothers with anxiety as well as comorbid anxiety and depressive symptoms had an increased risk of ADHD symptoms. Early detection and management for ADHD symptoms in children of mothers with anxiety and comorbid anxiety and depressive symptoms are needed.DisclosureNo significant relationships.
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Albuquerque, Luciana, Ana Rita S. Valente, António Teixeira, Daniela Figueiredo, Pedro Sa-Couto, and Catarina Oliveira. "Association between acoustic speech features and non-severe levels of anxiety and depression symptoms across lifespan." PLOS ONE 16, no. 4 (April 8, 2021): e0248842. http://dx.doi.org/10.1371/journal.pone.0248842.
Анотація:
Background Several studies have investigated the acoustic effects of diagnosed anxiety and depression. Anxiety and depression are not characteristics of the typical aging process, but minimal or mild symptoms can appear and evolve with age. However, the knowledge about the association between speech and anxiety or depression is scarce for minimal/mild symptoms, typical of healthy aging. As longevity and aging are still a new phenomenon worldwide, posing also several clinical challenges, it is important to improve our understanding of non-severe mood symptoms’ impact on acoustic features across lifetime. The purpose of this study was to determine if variations in acoustic measures of voice are associated with non-severe anxiety or depression symptoms in adult population across lifetime. Methods Two different speech tasks (reading vowels in disyllabic words and describing a picture) were produced by 112 individuals aged 35-97. To assess anxiety and depression symptoms, the Hospital Anxiety Depression Scale (HADS) was used. The association between the segmental and suprasegmental acoustic parameters and HADS scores were analyzed using the linear multiple regression technique. Results The number of participants with presence of anxiety or depression symptoms is low (>7: 26.8% and 10.7%, respectively) and non-severe (HADS-A: 5.4 ± 2.9 and HADS-D: 4.2 ± 2.7, respectively). Adults with higher anxiety symptoms did not present significant relationships associated with the acoustic parameters studied. Adults with increased depressive symptoms presented higher vowel duration, longer total pause duration and short total speech duration. Finally, age presented a positive and significant effect only for depressive symptoms, showing that older participants tend to have more depressive symptoms. Conclusions Non-severe depression symptoms can be related to some acoustic parameters and age. Depression symptoms can be explained by acoustic parameters even among individuals without severe symptom levels.
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Liukkonen, T., P. Räsänen, J. Jokelainen, M. Leinonen, M. R. Järvelin, V. B. Meyer-Rochow, and M. Timonen. "The association between anxiety and C-reactive protein (CRP) levels: Results from the Northern Finland 1966 Birth Cohort Study." European Psychiatry 26, no. 6 (September 2011): 363–69. http://dx.doi.org/10.1016/j.eurpsy.2011.02.001.
Анотація:
AbstractBackgroundAnxiety frequently accompanies low-grade inflammation-associated conditions like depression, insulin resistance, coronary heart disease and metabolic syndrome. The association between anxiety and low-grade inflammation is, unlike between depression and low-grade inflammation, a very sparsely studied area in general populations. The aim of the present study was to investigate whether anxiety symptoms as well as comorbid anxiety and depressive symptoms are associated with low-grade inflammation at population level.MethodsThe general population-based Northern Finland 1966 Birth Cohort was followed until age 31 (n = 2688 males and 2837 females), when the highly sensitive CRP concentrations were measured. Anxiety and depressive symptoms were defined by Hopkins Symptom Checklist-25 (HSCL-25).ResultsAfter adjusting for confounders, logistic regression analyses showed that anxiety symptoms alone increased the probability for elevated hs-CRP levels (> 3.0 mg/L) in males over two-fold (2.19 CI 95% 1.08–4.46), while comorbid anxiety and depressive symptoms caused a 1.7-fold (1.76 CI 95% 1.13–2.74) increase in the probability for elevated hs-CRP levels (1.0–3.0 mg/L).ConclusionsOur results support the hypothesis that anxiety as well as comorbid anxiety and depression can be associated with an increased risk for low-grade inflammation in males at population level.
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Francis, Benedict, Jesjeet Gill, Ng Yit Han, Chiara Petrus, Fatin Azhar, Zuraida Ahmad Sabki, Mas Said, Koh Ong Hui, Ng Chong Guan, and Ahmad Sulaiman. "Religious Coping, Religiosity, Depression and Anxiety among Medical Students in a Multi-Religious Setting." International Journal of Environmental Research and Public Health 16, no. 2 (January 17, 2019): 259. http://dx.doi.org/10.3390/ijerph16020259.
Анотація:
Medical students are vulnerable to depression and anxiety due to the nature of their academic life. This study aimed to determine the prevalence of depressive and anxiety symptoms among medical students and the association between religious coping, religiosity and socio-demographic factors with anxiety and depressive symptoms. A cross sectional design was used for this study. Scales used were the Malay version of the Duke Religious Index (DUREL-M), the Malay version of the Brief Religious Coping Scale (Brief RCOPE) and the Malay version Hospital and Anxiety Depression Scale (HADS-M). 622 students participated in this study. They scored moderately on the organized (mean: 3.51) and non-organized religious (mean: 3.85) subscales of the DUREL, but had high intrinsic religiosity (mean: 12.18). The prevalence of anxiety and depressive symptoms were 4.7% and 17.4% respectively, which is lower than local as well as international data. Islam, negative religious coping and the presence of depressive symptoms were significantly associated with anxiety symptoms. Only the presence of anxiety symptoms was significantly associated with depressive symptoms. Negative religious coping, rather than positive religious coping, has significant association with depressive and anxiety symptoms. Redirecting focus towards negative religious coping is imperative to boost mental health outcomes among medical students.
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McGuinn, Laura A., Iván Gutiérrez-Avila, Maria José Rosa, Allan Just, Brent Coull, Itai Kloog, Marcela Tamayo Ortiz, et al. "Association between prenatal and childhood PM2.5 exposure and preadolescent anxiety and depressive symptoms." Environmental Epidemiology 8, no. 1 (December 15, 2023): e283. http://dx.doi.org/10.1097/ee9.0000000000000283.
Анотація:
Background: Fine particulate matter (PM2.5) exposure has been linked to anxiety and depression in adults; however, there is limited research in the younger populations, in which symptoms often first arise. Methods: We examined the association between early-life PM2.5 exposure and symptoms of anxiety and depression in a cohort of 8–11-year-olds in Mexico City. Anxiety and depressive symptoms were assessed using the Spanish versions of the Revised Children’s Manifest Anxiety Scale and Children’s Depression Inventory. Daily PM2.5 was estimated using a satellite-based exposure model and averaged over several early and recent exposure windows. Linear and logistic regression models were used to estimate the change in symptoms with each 5-µg/m3 increase in PM2.5. Models were adjusted for child’s age, child’s sex, maternal age, maternal socioeconomic status, season of conception, and temperature. Results: Average anxiety and depressive symptom T-scores were 51.0 (range 33–73) and 53.4 (range 44–90), respectively. We observed consistent findings for exposures around the fourth year of life, as this was present for both continuous and dichotomized anxiety symptoms, in both independent exposure models and distributed lag modeling approaches. This window was also observed for elevated depressive symptoms. An additional consistent finding was for PM2.5 exposure during early pregnancy in relation to both clinically elevated anxiety and depressive symptoms, this was seen in both traditional and distributed lag modeling approaches. Conclusion: Both early life and recent PM2.5 exposure were associated with higher mental health symptoms in the child highlighting the role of PM2.5 in the etiology of these conditions.
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Zhang, Chenxi, Shufei Zeng, Yan Xu, Shuai Liu, Shixu Du, Leqin Fang, Zhihong Lv, Lili Zhang, and Bin Zhang. "Baseline symptoms of depression and anxiety negatively impact the effectiveness of CBTi in treating acute insomnia among young adults." General Psychiatry 36, no. 3 (May 2023): e101013. http://dx.doi.org/10.1136/gpsych-2023-101013.
Анотація:
BackgroundCognitive–behavioural therapy for insomnia (CBTi) is the first-line treatment for those with this sleep disorder. However, depressive and anxiety symptoms often co-occur with acute insomnia, which may affect the effectiveness of CBTi treatment.AimsThis study aimed to determine the impact of depressive and anxiety symptoms on the efficacy of CBTi in treating acute insomnia.MethodsA single-arm clinical trial was conducted among individuals who have acute insomnia. Participants underwent self-guided CBTi for 1-week. Their insomnia, depressive symptoms and anxiety symptoms were evaluated using the Insomnia Severity Index and the Hospital Anxiety and Depression Scale at baseline, post-treatment and 3-month follow-up. Repeated measures analysis of variance was used to assess the effectiveness of CBTi in treating insomnia, depressive symptoms and anxiety symptoms. A multivariate Cox regression model was used to determine the impact of depressive and anxiety symptoms on insomnia.ResultsThe study found significant reductions in insomnia, depressive symptoms and anxiety symptoms at both post-treatment and 3-month follow-up (F=17.45, p<0.001; F=36.37, p=0.001; and F=81.51, p<0.001, respectively). The duration of CBTi treatment had a positive impact on insomnia recovery (hazard ratio (HR)=0.94, p=0.018). However, baseline depressive symptoms (HR=1.83, p=0.004) and baseline anxiety symptoms (HR=1.99, p=0.001) had significant negative effects on insomnia recovery.ConclusionsThe study showed that a 1-week self-guided CBTi treatment is effective in treating acute insomnia and comorbid depressive and anxiety symptoms. However, baseline depressive and anxiety symptoms negatively impact treatment effectiveness. Therefore, clinicians should assess for depressive and anxiety symptoms before treating acute insomnia with monotherapy CBTi.
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Adams, Kiera Louise, Kate E. Saunders, Charles Donald George Keown-Stoneman, and Anne C. Duffy. "Mental health trajectories in undergraduate students over the first year of university: a longitudinal cohort study." BMJ Open 11, no. 12 (November 30, 2021): e047393. http://dx.doi.org/10.1136/bmjopen-2020-047393.
Анотація:
ObjectiveThis study examined the association between candidate psychosocial and lifestyle variables and the trajectories of clinically significant anxiety and depressive symptoms from entry to completion of first-year university.DesignA longitudinal cohort studyParticipantsFirst-year undergraduate studentsMethodsWe analysed the responses of 1686 first-year undergraduate students attending Queen’s University who completed electronic surveys at both the beginning and completion of their academic year. Predictors of change in positive anxiety and depressive symptom screens (based on exceeding validated symptom threshold scores) were identified using logistic regression.ResultsIncreased university connectedness reduced the odds of emergent significant depressive and anxiety symptoms in healthy students and increased the odds of recovery in students who screened positive at the start of university. Students who screened positive for depression or anxiety at university entry were less likely to recover if they had a lifetime history of internalising disorders. Healthy students who increased their drug use over their first year had higher odds of developing significant levels of both anxiety and depressive symptoms by completion of the academic year.ConclusionsModerate to severe levels of anxiety and depressive symptoms are common among students at entry to university and persist over the first year. University connectedness may mitigate the risk of persistent or emergent symptoms, whereas drug use appears to increase these risks. Findings have implications for university well-being initiatives.
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Safiah, Mhd Homam, Khaled Kalalib Al Ashabi, Tasnim Haj-Abow, Mhd Obai Alchallah, Naram Khalayli, and Maysoun Kudsi. "Exploring associations with depressive and anxiety symptoms among Syrian patients with ankylosing spondylitis undergoing biological treatment: A cross-sectional study." Medicine 103, no. 14 (April 5, 2024): e37708. http://dx.doi.org/10.1097/md.0000000000037708.
Анотація:
People with ankylosing spondylitis (AS) are vulnerable group to experience mood disorders. It is crucial to identify factors that contribute to depression and anxiety in order to improve outcomes. This study seeks to determine the rates of depression and anxiety in Syrian AS patients, as well as identify potential predictors for these conditions. This cross-sectional study was conducted using convenience sampling at the Biological Treatment Unit of the Rheumatology Department of the Damascus Hospital. Data were collected from face-to-face interviews with patients using validated structural questionnaire. A multivariate linear regression model was used to investigate potential predictive factors of depressive and anxiety symptoms. Of the 103 patients, 49.5% showed clinically significant depressive symptoms, and 36.9 % showed clinically significant anxiety symptoms. Multivariate linear regression indicated that depressive and anxiety symptoms were predicted by job layoff, hip pain, positive history of mental distress, poor quality of life, severe fatigue, and high frequency of sleep disturbance with relatively high explanatory powers. depressive and anxiety symptoms were predicted by disease activity scores but with low explanatory power. This study demonstrated high levels of that depressive and anxiety symptoms among Syrian patients with AS undergoing biological treatment. Poor quality of life, severe fatigue, and high-frequency sleep disturbances are major predictive factors for depressive and anxiety symptoms. Screening for depression and anxiety holds significant importance in the comprehensive management of ankylosing spondylitis even in the context of concurrent biological treatment administration.
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Brown, H. M., M. A. Waszczuk, H. M. S. Zavos, M. Trzaskowski, A. M. Gregory, and T. C. Eley. "Cognitive content specificity in anxiety and depressive disorder symptoms: a twin study of cross-sectional associations with anxiety sensitivity dimensions across development." Psychological Medicine 44, no. 16 (April 16, 2014): 3469–80. http://dx.doi.org/10.1017/s0033291714000828.
Анотація:
Background.The classification of anxiety and depressive disorders has long been debated and has important clinical implications. The present study combined a genetically sensitive design and multiple time points to investigate cognitive content specificity in anxiety and depressive disorder symptoms across anxiety sensitivity dimensions, a cognitive distortion implicated in both disorders.Method.Phenotypic and genetic correlations between anxiety sensitivity dimensions, anxiety and depressive disorder symptoms were examined at five waves of data collection within childhood, adolescence and early adulthood in two representative twin studies (n pairs = 300 and 1372).Results.The physical concerns dimension of anxiety sensitivity (fear of bodily symptoms) was significantly associated with anxiety but not depression at all waves. Genetic influences on physical concerns overlapped substantially more with anxiety than depression. Conversely, mental concerns (worry regarding cognitive control) were phenotypically more strongly associated with depression than anxiety. Social concerns (fear of publicly observable symptoms of anxiety) were associated with both anxiety and depression in adolescence. Genetic influences on mental and social concerns were shared to a similar extent with both anxiety and depression.Conclusions.Phenotypic patterns of cognitive specificity and broader genetic associations between anxiety sensitivity dimensions, anxiety and depressive disorder symptoms were similar at all waves. Both disorder-specific and shared cognitive concerns were identified, suggesting it is appropriate to classify anxiety and depression as distinct but related disorders and confirming the clinical perspective that cognitive therapy is most likely to benefit by targeting cognitive concerns relating specifically to the individual's presenting symptoms across development.
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Tassi, S., G. Rioli, G. Mattei, S. Ferrari, and G. M. Galeazzi. "Impact of anxiety-depressive symptoms on outpatients’ quality of life: Preliminary results from an Italian observational study." European Psychiatry 41, S1 (April 2017): S319. http://dx.doi.org/10.1016/j.eurpsy.2017.02.237.
Анотація:
IntroductionSeveral studies have shown an association between the Short-Form 36 (SF36) scores and anxiety-depressive symptoms, suggesting that depression in particular could reduce Quality of Life (QoL) to the same, and even greater, extent than chronic non-communicable diseases, such as diabetes and hypertension.AimsTo explore the relationship among QoL and anxiety, depressive and anxiety-depressive symptoms in an outpatient sample.MethodsCross-sectional study. Inclusion criteria: outpatients aged ≥40 years, without history for cancer, attending colonoscopy after positive faecal occult blood test. Collected data: blood pressure, blood glucose, lipid profile. Psychometric test: Hospital Anxiety and Depression Scale (HADS). QoL was assessed with SF36. Statistics performed with STATA13.Results54 patients enrolled (27 females). Sixteen patients (30.2%) were positive for anxiety symptoms, ten (18.9%) for depressive symptoms and five (9.4%) for anxiety-depressive symptoms. The perceived QoL was precarious in twelve subjects (22.2%): eight (15.9%) had low score (≤ 42) at “Mental Component Summary” (MCS) subscale, three (5.7%) at the “Mental Health” item and one patient (1.9%) at the “Vitality” one. At the multiple regression analysis, depressive (OR = 28.63; P = 0.01) and anxiety-depressive symptoms (OR = 11.16; P = 0.02) were associated with MCS.ConclusionsThe association emerging from the present study between depressive/anxiety symptoms and the MCS component of SF36 is consistent with available literature. Study design and small sample size do not allow to generalize results, that need further studies to be confirmed.Disclosure of interestThe authors have not supplied their declaration of competing interest.
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Nikolaeva, P. V., Y. S. Fofanova, I. A. Nikiforov, P. V. Aronov, and G. N. Belskaya. "Atypical depression: frequency of symptoms." Meditsinskiy sovet = Medical Council, no. 21 (November 19, 2022): 106–11. http://dx.doi.org/10.21518/2079-701x-2022-16-21-106-111.
Анотація:
Introduction. The relevance of the study is determined by the increase of atypical forms of depression, which is especially characteristic of outpatient affective disorders. In this case, the frequency of occurrence of individual atypical depressive symptoms requires clarification.Aim. To determinate the prevalence of atypical symptoms in patients with depressive disorder.Materials and methods. Patients (87 subjects) with depressive disorder, aged 18–70, who gave inform consent. The selection criterion was the result of psychometric research using The Hospital Anxiety and Depression Scale (HADS): the study included patients who scored more than 7 points. Patients with severe organic insufficiency and neurological diseases, alcohol and substance abuse were excluded. The study used clinical psychometric and statistical methods. The main examination tool is stimulus material in the form of a table with a list of atypical depressive symptoms.Results. Based on the psychometric assessment, patients were divided into two groups: patients with subclinical depression included 19 patients, patients with clinically severe depression included 68 patients. Among patients with subclinical depression, increased anxiety (89.5%), mood reactivity (84.2%), hypersonium (78.9%), hyperphagia (73.7%) and somatized symptoms (73.7%) were most often recorded. Among patients with clinically pronounced depression, increased anxiety (91.2%), somatized symptoms (80.9%), hypersonium (79.4%) and inverted daily rhythm (72.1%) were most common.Conclusion. The data obtained confirm the high prevalence of symptoms of atypical depression among patients with depressive spectrum disorders. The frequent occurrence of anxious and somatized symptoms in the structure of depression, as well as hypersomnia, was demonstrated. It seems relevant to further study the prevalence of separate symptoms of atypical depression.
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Izuka, EO, TO Iyidobu, CE Obiora-Izuka, JT Enebe, AD Onyeabochukwu, PO Nkwo, and UI Nwagha. "Evaluation of Anxiety and Depression among Pregnant Women in Enugu, Nigeria." Nigerian Journal of Clinical Practice 26, no. 9 (September 2023): 1368–76. http://dx.doi.org/10.4103/njcp.njcp_196_23.
Анотація:
ABSTRACT Background: Maternal depression and anxiety during pregnancy are public health concerns. They are commonly reported among pregnant women from all over the world. Maternal mental health has not been prioritized, especially in low- and middle-income countries. Aim: To evaluate depression and anxiety among pregnant women who receive antenatal care in four randomly selected hospitals in Enugu, Nigeria. Materials and Methods: A multicenter questionnaire-based cross-sectional survey of 434 pregnant women was conducted at four selected health institutions offering antenatal services in Enugu, Enugu State. The prevalence of anxiety and depression was assessed using the hospital anxiety and depression scale (HADS). Factors associated with anxiety and depression were determined using logistic regression. P <0.05 was taken as significant. Results: The mean age of study participants was 30.09 ± 5.12 years. The proportion of participants with depressive symptoms and borderline depressive symptoms was 9.7% and 11.1%, respectively. The proportion of participants with anxiety symptoms and borderline anxiety symptoms was 10.1% and 15.7%, respectively. Husband’s employment status (P = 0.033, odds ratios (OR) =0.354, 95% confidence intervals (CI) =0.137–0.918) and gestational age (P = 0.042, OR = 2.066, 95% CI = 1.028–4.151) were the only factors associated with depressive symptoms, while only educational level (P = 0.001, OR = 3.552, 95% CI = 1.674–7.537) and husband’s employment status (P = 0.013, OR = 0.295, 95% CI = 0.113–0.772) were the only factors associated with anxiety symptoms. Conclusions: Anxiety and depressive symptoms are relatively common in antenatal women in Enugu. The factors associated with depressive and anxiety symptoms were the respondent’s educational level, gestational age, and the employment status of the husband.
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Dong, Fanghong, and Nancy Hodgson. "ASSESSING SYMPTOM NETWORKS OF DEPRESSIVE SYMPTOMS IN OLDER ADULTS: A CROSS-NATIONAL POPULATION-BASED STUDY." Innovation in Aging 7, Supplement_1 (December 1, 2023): 752. http://dx.doi.org/10.1093/geroni/igad104.2432.
Анотація:
Abstract Introduction Older adults often experience elevated sleep disturbances, depressive and anxiety symptoms. However, the role of sleep disturbances in explaining individual variability in depressive and anxiety symptoms among older adults is poorly understood. Methods The sample was derived from the National Social Life, Health, and Aging Project, a nationally representative longitudinal study among American older adults. MCI was defined as Montreal Cognitive Assessment scored less than 23. Subjective insomnia symptoms and objective sleep measures (total sleep time, wake after sleep onset, percentage sleep) obtained from actigraphy were used. Validated measures on depressive and anxiety symptoms were collected both at round 2(N=645) and round 3(N=456). Multiple regressions were conducted to establish cross-sectional and longitudinal associations between sleep disturbances, depressive and anxiety symptoms. Results Cross-sectionally, compared to cognitively intact older adults, severe insomnia symptoms were associated with poorer depressive symptoms(B=0.40, p< 0.01) in older adults with MCI. Severe insomnia symptoms were associated with poorer anxiety symptoms(B=0.13, p< 0.01) in older adults, and no interaction effects were found by MCI groups. Longitudinally, insomnia symptoms at round 2 were associated with poorer depressive symptoms and poorer anxiety symptoms in older adults at round 3, but no interaction effects were found by MCI groups. No significant relationships were found between objective sleep disturbances and depressive/anxiety symptoms both cross-sectionally and longitudinally. Conclusions The findings provide further insight into insomnia symptoms that may be associated with increased risks for developmental depressive and anxiety symptoms. These data suggest that targeting insomnia treatment may confer long-term mental health benefits.
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Chaplin, Tara M., Jane E. Gillham, and Martin E. P. Seligman. "Gender, Anxiety, and Depressive Symptoms." Journal of Early Adolescence 29, no. 2 (June 11, 2008): 307–27. http://dx.doi.org/10.1177/0272431608320125.
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TUCKER, MIRIAM E. "Chamomile Eases Anxiety, Depressive Symptoms." Clinical Psychiatry News 38, no. 5 (May 2010): 29. http://dx.doi.org/10.1016/s0270-6644(10)70240-x.
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Noël, Ingrid, Sylvie Dodin, Stéphanie Dufour, Marie-Ève Bergeron, Jessica Lefebvre, and Sarah Maheux-Lacroix. "Evaluation of predictor factors of psychological distress in women with unexplained infertility." Therapeutic Advances in Reproductive Health 16 (January 2022): 263349412110680. http://dx.doi.org/10.1177/26334941211068010.
Анотація:
Objective: The objective of this study was to establish the frequency of anxiety and depressive symptoms among women diagnosed with unexplained infertility and to identify risk factors. Methods: We conducted a descriptive cross-sectional study. Forty-two women from the CHU de Quebec fertility clinic were recruited. Women completed the ‘Hospital Anxiety and Depression Scale’ (HADS) self-administered questionnaire, used to estimate prevalence of anxiety and depressive symptoms (score ≥ 8). Results: Overall, 55% ( n = 23) of participants were identified with anxiety or depressive symptoms according to the HADS questionnaire. Anxiety symptoms were more frequent (55%) compared with depressive symptoms (10%). According to a logistic regression model, being under 35 years old [odds ratio (OR) = 16.6, confidence interval (CI): 1.9–25.0], never had a previous spontaneous abortion (OR = 5.6, CI: 1.1–43.5) and never sought fertility treatment (OR = 5.5, CI: 1.1–45.4) were associated with a higher risk of anxiety and depressive symptoms. Conclusion: Anxiety and depressive symptoms are common among women with unexplained infertility, and strategies should be developed to better support and treat this high-risk population.
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Sharma, Rachit, Harpreet Singh, Kaushik Chatterjee, Pookala Shivaram Bhat, Kalpana Srivastava, and Rajiv Kumar Saini. "Anxiety and Depression in Parents of Children and Adolescents with Intellectual Disability." Annals of Indian Psychiatry 7, no. 4 (2023): 334–38. http://dx.doi.org/10.4103/aip.aip_197_22.
Анотація:
Abstract Background: Parents of the children and adolescents with intellectual disability (ID) are prone to psychological distress than as compared to parents of normally developing children and adolescents. Various biopsychosocial factors affect the perception and manifestation of this stress and influences difference in quality and severity in psychological outcomes. When a couple faces stress of caregiving as a unit, it is worthwhile to know and assess distribution pattern amongst the primary care giver and the other parent. Aim: The aim of the study is to evaluate the proportional distribution of depression and anxiety in primary care giver and the other parent in parents of children and adolescents with ID. Materials and Methods: Using a Cross-sectional observational study design, 99 parents (99 fathers and 98 mothers) of 99 children and adolescents (up to 18 yrs of age) with Intellectual Disability were assessed for Depressive and Anxiety symptoms using Hospital Anxiety and Depression Scale (HADS). Comparison of proportional distribution of psychiatric morbidity among fathers and mothers (primary care giver) was done using 2 independent sample proportion tests. Results: The mothers were found to be the primary care givers. 35.4% of fathers and 66.3% of mothers had significant depressive symptoms. 57.6% of fathers and 91.8% of mothers had significant anxiety symptoms. In 33 couples, fathers did not report anxiety or depressive symptoms but corresponding 27 mothers reported significant anxiety or depressive symptoms or both. In rest of the couples in whom fathers reported anxiety and/or depressive symptoms, the corresponding mothers also reported. In six couples where mothers did not report anxiety or depression, the fathers also did not report any anxiety or depressive symptoms. Conclusion: Depressive and Anxiety symptoms are very prevalent in parents of children with ID. Their proportion is significantly high in primary care giver (mother) as comparedto corresponding other parent (father). There is unequal distribution of anxiety and depression in these parents with a skew towards mother.
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Bakuleva, N. I., O. Yu Shiryaev, V. A. Zemskova, O. N. Choporov, A. M. Zemskov, N. A. Ermolenko, and E. V. Dorokhov. "A correlation between anxiety-depressive symptoms and immune-metabolic parameters in patients with mixed anxiety and depressive disorder." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 2 (February 22, 2024): 173–83. http://dx.doi.org/10.33920/med-01-2402-01.
Анотація:
According to literature data, anxiety and depressive disorders are the most common mental diseases worldwide. Currently, a hypothesis of possible immune metabolic regulation of the central nervous system was put forward. The authors evaluated the indicators of humoral, cellular, and metabolic immunity in patients suffering from mixed anxiety and depressive disorder, who were under the supervision of a psychiatrist at the day hospital of the Voronezh Regional Clinical Psychoneurological Dispensary. Indicators of anxiety and depression were assessed by means of psychometric method, clinical interview, and clinical psychopathological examination, and the indicators of immune and metabolic status were examined. It was found that symptoms of anxiety and depression were accompanied by changes in immune and metabolic status. It is supposed that variations in clinical, immunological, and metabolic parameters are coordinated elements of a single pathogenetic mechanism for the formation of anxiet y-depressive spectrum disorders.
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Klingbeil, Julian, Max-Lennart Brandt, Max Wawrzyniak, Anika Stockert, Hans R. Schneider, Petra Baum, Karl-Titus Hoffmann, and Dorothee Saur. "Association of Lesion Location and Depressive Symptoms Poststroke." Stroke 52, no. 3 (March 2021): 830–37. http://dx.doi.org/10.1161/strokeaha.120.031889.
Анотація:
Background and Purpose: Poststroke depression is a common stroke sequel, yet its neurobiological substrates are still unclear. We sought to determine whether specific lesion locations are associated with depressive symptoms after stroke. Methods: In a prospective study, 270 patients with first ever stroke were repeatedly tested with the depression subscale of the Hospital Anxiety and Depression Scale within the first 4 weeks and 6 months after stroke. Voxel-based lesion behavior mapping based on clinical imaging was performed to test for associations between symptoms of depression and lesion locations. Results: Frequency of poststroke depression (Hospital Anxiety and Depression Scale-D score >7) after 6 months was 19.6%. Higher Hospital Anxiety and Depression Scale-D scores for depression within the first 4 weeks were the only independent predictor for poststroke depression after 6 months in a multiple logistic regression also including age, sex, lesion volume, stroke severity, Barthel-Index, and the anxiety subscale of the Hospital Anxiety and Depression Scale. Nonparametric permutation-test based voxel-based lesion behavior mapping identified a cluster of voxels mostly within the left ventrolateral prefrontal cortex where lesions were significantly associated with more depressive symptoms after 6 months. No such association was observed within the right hemisphere despite better lesion coverage. Conclusions: Lesions in the left ventrolateral prefrontal cortex increase the risk of depressive symptoms 6 months poststroke. Lesions within the right hemisphere are unrelated to depressive symptoms. Recognition of left frontal lesions as a risk factor should help in the early diagnosis of poststroke depression through better risk stratification. The results are in line with evidence from functional imaging and noninvasive brain stimulation in patients without focal brain damage indicating that dysfunction in the left lateral prefrontal cortex contributes to depressive disorders.
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Sawhney, Manisha, Seth Kunen, and Ashum Gupta. "Depressive Symptoms and Coping Strategies Among Indian University Students." Psychological Reports 123, no. 2 (December 21, 2018): 266–80. http://dx.doi.org/10.1177/0033294118820511.
Анотація:
Depression is now the leading cause of disability worldwide, and globally more than 300 million people of all ages suffer from depression. Depression, despite its major health consequences, frequently goes unnoticed among university students, since their lives are often filled with symptoms normally associated with depression (e.g., loss of sleep, low energy, anxiety, and sadness). Successful adaptation to depression depends on the use of adequate coping strategies. The extent to which university students in India with high and low levels of depressive symptoms use adequate or inadequate coping strategies has not been evaluated. Based on the Center for Epidemiological Scale for Depression score, students were assigned to either the high depressive symptoms or the low depressive symptoms group. We used the Coping Response Inventory-Adult to determine the dominant coping strategies used by the two depressive symptoms groups. The high depressive symptom group resorted to more avoidant coping strategies than the low depressive symptom group, and women were more likely to use avoidant coping strategies than men.
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Salih Joelsson, L., T. Tydén, K. Wanggren, M. K. Georgakis, J. Stern, A. Berglund, and A. Skalkidou. "Anxiety and depression symptoms among sub-fertile women, women pregnant after infertility treatment, and naturally pregnant women." European Psychiatry 45 (September 2017): 212–19. http://dx.doi.org/10.1016/j.eurpsy.2017.07.004.
Анотація:
AbstractBackground:Infertility has been associated with psychological distress, but whether these symptoms persist after achieving pregnancy via assisted reproductive technology (ART) remains unclear. We compared the prevalence of anxiety and depressive symptoms between women seeking for infertility treatment and women who conceived after ART or naturally.Methods:Four hundred and sixty-eight sub-fertile non-pregnant women, 2972 naturally pregnant women and 143 women pregnant after ART completed a questionnaire in this cross-sectional study. The Anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A≥8) and Edinburgh Postnatal Depression Scale (EPDS≥12) were used for assessing anxiety and depressive symptoms, respectively. Multivariate Poisson regression models with robust variance were applied to explore associations with anxiety and depressive symptoms.Results:The prevalence of anxiety and depressive symptoms among sub-fertile, non-pregnant women (57.6% and 15.7%, respectively) were significantly higher compared to women pregnant after ART (21.1% and 8.5%, respectively) and naturally pregnant women (18.8% and 10.3%, respectively). History of psychiatric diagnosis was identified as an independent risk factor for both anxiety and depressive symptoms. The presence of at least one unhealthy lifestyle behavior (daily tobacco smoking, weekly alcohol consumption, BMI≥25, and regular physical exercise < 2 h/week) was also associated with anxiety (Prevalence Ratio, PR: 1.24; 95%CI: 1.09–1.40) and depressive symptoms (PR: 1.25; 95%CI: 1.04–1.49).Conclusions:Women pregnant after ART showed no difference in anxiety and depressive symptoms compared to naturally pregnant women. However, early psychological counseling and management of unhealthy lifestyle behaviors for sub-fertile women may be advisable, particularly for women with a previous history of psychiatric diagnosis.
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Ingeborgrud, Christine Baalsrud, Beate Oerbeck, Svein Friis, Pål Zeiner, Are Hugo Pripp, Heidi Aase, Guido Biele, Søren Dalsgaard, and Kristin Romvig Overgaard. "Anxiety and depression from age 3 to 8 years in children with and without ADHD symptoms." Scientific Reports 13, no. 1 (September 16, 2023). http://dx.doi.org/10.1038/s41598-023-42412-7.
Анотація:
AbstractChildhood anxiety and depressive symptoms may be influenced by symptoms of attention deficit/hyperactivity disorder (ADHD). We investigated whether parent- and teacher-reported anxiety, depressive and ADHD symptoms at age 3 years predicted anxiety disorders and/or depression in children with and without ADHD at age 8 years. This study is part of the longitudinal, population-based Norwegian Mother, Father and Child Cohort Study. Parents of 3-year-olds were interviewed, and preschool teachers rated symptoms of anxiety disorders, depression and ADHD. At age 8 years (n = 783), Child Symptom Inventory-4 was used to identify children who fulfilled the diagnostic criteria for anxiety disorders and/or depression (hereinafter: Anx/Dep), and ADHD. Univariable and multivariable logistic regression analyses were used. In the univariable analyses, parent-reported anxiety, depressive and ADHD symptoms, and teacher-reported anxiety symptoms at age 3 years all significantly predicted subsequent Anx/Dep. In the multivariable analyses, including co-occurring symptoms at age 3 years and ADHD at 8 years, parent-reported anxiety and depressive symptoms remained significant predictors of subsequent Anx/Dep. At age 3 years, regardless of ADHD symptoms being present, asking parents about anxiety and depressive symptoms, and teachers about anxiety symptoms, may be important to identify children at risk for school-age anxiety disorders and/or depression.
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Bugajski, Andrew, Hailey Morgan, Walter Wills, Kellcee Jacklin, Shirley Alleyne, Bishoy Kolta, Alexander Lengerich, and Kaitlyn Rechenberg. "Anxiety and Depressive Symptoms in Patients with COPD: Modifiable Explanatory Factors." Western Journal of Nursing Research, October 16, 2022, 019394592211299. http://dx.doi.org/10.1177/01939459221129949.
Анотація:
Anxiety and depressive symptoms affect up to 80% of people with chronic obstructive pulmonary disease (COPD). To reduce this symptom burden, clinicians should target modifiable explanatory factors while accounting for nonmodifiable explanatory factors of these symptoms. The purpose of this secondary data analysis was to examine which modifiable factors explain anxiety and depressive symptoms in COPD. This secondary data analysis of 1,760 COPD patients used multiple regression to explain anxiety and depressive symptoms from sets of modifiable patient characteristics and demographic controls. Clinically significant symptoms of anxiety or depression presented in 29.6% ( n = 526) of participants, and 20.6% ( n = 363) had both. Significant modifiable explanatory factors of both disorder symptoms were perceived functional status, functional capacity, psychosocial impact, symptom self-management, and significant symptoms for the other. Somatic symptom burden and dyspnea explained anxiety and depressive symptoms, respectively. Addressing these modifiable factors may reduce anxiety and depressive symptoms in patients with COPD.
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Thomas, Garrett A., Kaitlin E. Riegler, Erin T. Guty, and Peter A. Arnett. "Relationship Between Self-Reported Concomitant Depressive and Anxiety Symptoms and the Post-Concussion Symptoms Scale (PCSS)." Journal of the International Neuropsychological Society, December 13, 2021, 1–11. http://dx.doi.org/10.1017/s135561772100134x.
Анотація:
ABSTRACT Objectives: The current study explored how affective disturbances, particularly concomitant anxiety and depressive symptoms, impact baseline symptom self-reporting on the Post-Concussion Symptoms Scale (PCSS) in college athletes. Methods: Athletes were separated into four groups (Healthy Control (HC) (n = 581), Depression Only (n = 136), Anxiety Only (n = 54), Concomitant Depression/Anxiety (n = 62)) based on their anxiety and depression scores. Groups were compared on Total PCSS Score as well as 5 PCSS Symptom Cluster scores (Cognitive, Physical, Affective, Sleep, and Headache). Results: The three affective groups reported significantly greater symptomatology than HCs, with the Concomitant group showing the highest symptomatology scores across all clusters. The depressive symptoms only group also reported significantly elevated symptomatology, compared to HCs, on every symptom cluster except headache. The anxiety symptoms only group differed from HCs on only the cognitive symptoms cluster. Additionally, the Concomitant group reported significantly increased PCSS symptomatology, in terms of total scores and all 5 symptom clusters, compared to the depressive symptoms only and anxiety symptoms only groups. Conclusions: Our findings suggest that athletes experiencing concomitant depressive/anxiety symptoms report significantly greater levels of symptomatology across all 5 PCSS symptom clusters compared to HCs. Further, results suggest that athletes experiencing concomitant affective disturbance tend to report greater symptomatology than those with only one affective disturbance. These findings are important because, despite the absence of concussion, the concomitant group demonstrated significantly elevated symptomatology at baseline. Thus, future comparisons with post-concussion data should account for this increased symptomatology, as test results may be skewed by affective disturbances at baseline.
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Kong, Zhifei, Ximei Zhu, Suhua Chang, Yanping Bao, Yundong Ma, Wenwen Yu, Ran Zhu, et al. "Somatic symptoms mediate the association between subclinical anxiety and depressive symptoms and its neuroimaging mechanisms." BMC Psychiatry 22, no. 1 (December 29, 2022). http://dx.doi.org/10.1186/s12888-022-04488-9.
Анотація:
Abstract Background Subclinical anxiety, depressive and somatic symptoms appear closely related. However, it remains unclear whether somatic symptoms mediate the association between subclinical anxiety and depressive symptoms and what the underlying neuroimaging mechanisms are for the mediating effect. Methods Data of healthy participants (n = 466) and participants in remission of major depressive disorder (n = 53) were obtained from the Human Connectome Project. The Achenbach Adult Self-Report was adopted to assess anxiety, depressive and somatic symptoms. All participants completed four runs of resting-state functional magnetic resonance imaging. Mediation analyses were utilized to explore the interactions among these symptoms and their neuroimaging mechanisms. Results Somatic symptoms partially mediated the association between subclinical anxiety and depressive symptoms in healthy participants (anxiety→somatic→depression: effect: 0.2785, Boot 95% CI: 0.0958–0.3729; depression→somatic→anxiety: effect: 0.0753, Boot 95% CI: 0.0232–0.1314) and participants in remission of MDD (anxiety→somatic→depression: effect: 0.2948, Boot 95% CI: 0.0357–0.7382; depression→somatic→anxiety: effect: 0.0984, Boot 95% CI: 0.0007–0.2438). Resting-state functional connectivity (FC) between the right medial superior frontal gyrus and the left thalamus and somatic symptoms as chain mediators partially mediated the effect of subclinical depressive symptoms on subclinical anxiety symptoms in healthy participants (effect: 0.0020, Boot 95% CI: 0.0003–0.0043). The mean strength of common FCs of subclinical depressive and somatic symptoms, somatic symptoms, and the mean strength of common FCs of subclinical anxiety and somatic symptoms as chain mediators partially mediated the effect of subclinical depressive symptoms on subclinical anxiety symptoms in remission of MDD (effect: 0.0437, Boot 95% CI: 0.0024–0.1190). These common FCs mainly involved the insula, precentral gyri, postcentral gyri and cingulate gyri. Furthermore, FC between the triangular part of the left inferior frontal gyrus and the left postcentral gyrus was positively associated with subclinical anxiety, depressive and somatic symptoms in remission of MDD (FDR-corrected p < 0.01). Conclusions Somatic symptoms partially mediate the interaction between subclinical anxiety and depressive symptoms. FCs involving the right medial superior frontal gyrus, left thalamus, triangular part of left inferior frontal gyrus, bilateral insula, precentral gyri, postcentral gyri and cingulate gyri maybe underlie the mediating effect of somatic symptoms.
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Zhang, Yajuan, Yi Cui, Yijun Li, Hongliang Lu, He Huang, Jiaru Sui, Zhihua Guo, and Danmin Miao. "Network analysis of depressive and anxiety symptoms in older Chinese adults with diabetes mellitus." Frontiers in Psychiatry 15 (January 29, 2024). http://dx.doi.org/10.3389/fpsyt.2024.1328857.
Анотація:
BackgroundThe move away from investigating mental disorders as whole using sum scores to the analysis of symptom-level interactions using network analysis has provided new insights into comorbidities. The current study explored the dynamic interactions between depressive and anxiety symptoms in older Chinese adults with diabetes mellitus (DM) and identified central and bridge symptoms in the depression-anxiety network to provide potential targets for prevention and intervention for depression and anxiety.MethodsThis study used a cross-sectional design with data from the 2017–2018 wave of the Chinese Longitudinal Healthy Longevity Survey (CLHLS). A regularized partial correlation network for depressive and anxiety symptoms was estimated based on self-reported scales completed by 1685 older adults with DM aged 65 years or older. Depressive and anxiety symptoms were assessed using the 10-item Center for Epidemiologic Studies Depression Scale (CESD-10) and the Seven-Item Generalized Anxiety Disorder Scale (GAD-7), respectively. Expected influence (EI) and bridge expected influence (BEI) indices were calculated for each symptom.ResultsAccording to cutoff scores indicating the presence of depression and anxiety, the prevalences of depression and anxiety in our sample were 52.9% and 12.8%, respectively. The comorbidity rate of depression and anxiety was 11.5%. The six edges with the strongest regularized partial correlations were between symptoms from the same disorder. “Feeling blue/depressed”, “Nervousness or anxiety”, “Uncontrollable worry”, “Trouble relaxing”, and “Worry too much” had the highest EI values. “Nervousness or anxiety” and “Everything was an effort” exhibited the highest BEI values.ConclusionCentral and bridge symptoms were highlighted in this study. Targeting these symptoms may be effective in preventing the comorbidity of depressive and anxiety symptoms and facilitate interventions in older Chinese adults with DM who are at risk for or currently have depressive and anxiety symptoms.