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Статті в журналах з теми "Da peak"
1
Johnson, Rebecca A., Stephen M. Johnson, and Gordon S. Mitchell. "Catecholaminergic modulation of respiratory rhythm in an in vitro turtle brain stem preparation." Journal of Applied Physiology 85, no. 1 (July 1, 1998): 105–14. http://dx.doi.org/10.1152/jappl.1998.85.1.105.
Повний текст джерелаАнотація:
An in vitro brain stem preparation from adult turtles was used to determine effects of dopamine (DA) and norepinephrine (NE) on the pattern of respiratory motor output recorded from hypoglossal nerve roots (XII). Bath-applied DA (10–200 μM) increased the frequency of respiratory bursts (peaks) from 0.9 ± 0.2 to 2.4 ± 0.3 (SE) peaks/min, resulting in a 99 ± 9% increase in neural minute activity. R[+]-SCH-23390 (10 μM, D1 antagonist) and eticlopride (20 μM, D2 antagonist) attenuated the DA-mediated increase in peak frequency by 52 and 59%, respectively. On the other hand, the DA-receptor agonists apomorphine (D1, D2), quinelorane (D2), and SKF-38393 (D1) had no effect on peak frequency. Prazosin, an α1-adrenergic antagonist (250 nM) abolished the DA-mediated frequency increase. Although NE (10–200 μM) and phenylephrine (10–200 μM, α1-adrenergic agonist) increased peak frequency from 0.5 ± 0.1 to 1.2 ± 0.3 peaks/min and from 0.6 ± 0.1 to 1.0 ± 0.2 peaks/min, respectively, these effects were not as large as that with DA alone. The data suggest that both dopaminergic and adrenergic receptor activation in the brain stem increase respiratory frequency in turtles, but the DA receptor-mediated increase is dependent on coactivation of α1-adrenergic receptors.
2
Franciulli, Patricia, Renan Furlanetto, Ricardo Pultrini, Flavia Souza, Marcia Barbanera, and Luis Mochizuki. "Effect of Kinesio Taping on isokinetic knee peak torque." Revista Neurociências 23, no. 02 (June 30, 2015): 255–59. http://dx.doi.org/10.4181/rnc.2015.23.02.1009.5p.
Повний текст джерела
3
Terini, Ricardo Andrade, Maria da Penha Albuquerque Potiens, Silvio Bruni Herdade, Marco Aurélio Guedes Pereira, João dos Santos Justo Pires, and Heber Simões Videira. "A medição da grandeza practical peak voltage na prática radiológica." Radiologia Brasileira 42, no. 6 (December 2009): 389–94. http://dx.doi.org/10.1590/s0100-39842009000600013.
Повний текст джерелаАнотація:
OBJETIVO: O objetivo deste trabalho foi estudar a grandeza practical peak voltage (PPV), determinada a partir da forma de onda de tensão aplicada a tubos radiológicos, e compará-la com algumas definições de kVp para diferentes tipos de geradores: monofásico (onda completa, clínico), trifásico (seis pulsos, clínico) e potencial constante (industrial). MATERIAIS E MÉTODOS: O trabalho envolveu a comparação do PPV medido invasivamente (utilizando um divisor de tensão) com a resposta de dois medidores comerciais não invasivos, além dos valores de outras grandezas usadas para medição da tensão de pico aplicada ao tubo de raios X, e a análise da variação do PPV com a ondulação percentual da tensão (ripple). RESULTADOS: Verificou-se que a diferença entre o PPV e as definições mais comuns de tensão de pico aumenta com o ripple. Os valores de PPV variaram em até 3% e 5%, respectivamente, na comparação entre medições invasivas e não invasivas feitas com os equipamentos trifásico e monofásico. CONCLUSÃO: Os resultados demonstraram que a principal grandeza de influência que afeta o PPV é o ripple da tensão. Adicionalmente, valores de PPV obtidos com medidores não invasivos devem ser avaliados considerando que eles dependem da taxa de aquisição e da forma de onda adquirida pelo instrumento.
4
Freitas, Eduardo Pacheco. "O desenvolvimento da arquitetura gótica a partir da filosofia escolástica." Nuntius Antiquus 9, no. 2 (December 31, 2013): 201–20. http://dx.doi.org/10.17851/1983-3636.9.2.201-220.
Повний текст джерелаАнотація:
This paper aims to explore the onset and peak of the development of Gothic architecture, religious art and architecture eminently urban, between the twelfth and thirteenth centuries in the medieval West, in a socio-religious Catholic hegemony. The message sent to the faithful through the Gothic architecture, replacing Romanesque, indicates in this case a major change in mindset, since we consider the importance of semiotics in art, architecture and urban space.
5
Chao, Yapeng, Shaoxiang Xiong, Xiulan Cheng, and Shijun Qian. "Mass Spectrometric Evidence of Heparin Disaccharides for the Catalytic Characterization of a Novel Endolytic Heparinase." Acta Biochimica et Biophysica Sinica 36, no. 12 (December 1, 2004): 840–44. http://dx.doi.org/10.1093/abbs/36.12.840.
Повний текст джерелаАнотація:
Abstract Heparinase from different sources can eliminate heparin or/and heparan sulfate into various low-molecular weight heparins with different characteristics. Porcine intestinal mucosa heparin was degraded into a series of oligosaccharides by a novel heparinase from the species Sphingobacterium. Disaccharide components from the digests were separated and purified by ultrafiltration and HPLC. Five major peaks appeared as three types according to their retention time. The mass spectrometry of peak I mainly gave the non-sulfated disaccharide with the mass of 379 Da. Peak II and III were indicated as two major monosulfated disaccharides with molecular mass of 417 and 459 Da respectively. Moreover, the peak III represented an Nacetyl disaccharide. Both peak IV and V showed the same mass of 496 Da, hinting that they were disulfate-substituted disaccharides. No trisulfate-substituted disaccharides were detected in the mixture of the heparin digest though they were abundant in the heparin structure. The results revealed that the heparinase might specifically cut the sites with low sulfated domain in heparin.
6
Powell, Douglas W., Cora E. Scruggs, D. S. Blaise Williams, Songning Zhang, Brett A. Windsor, and John D. Willson. "Effect Of Gender And Increasing Treadmill Velocity On Peak Ankle Plantarflexor Powers During Level Walking." Medicine & Science in Sports & Exercise 46 (May 2014): 416. http://dx.doi.org/10.1249/01.mss.0000494422.09225.da.
Повний текст джерела
7
Zhao, Chenzi. "EFFECT OF SPORTS FATIGUE ON PLANTAR PRESSURE DISTRIBUTION OF HEALTHY MALE COLLEGE STUDENTS." Revista Brasileira de Medicina do Esporte 28, no. 5 (October 2022): 398–401. http://dx.doi.org/10.1590/1517-8692202228052021_0517.
Повний текст джерелаАнотація:
ABSTRACT Objective: To understand the influence of sports fatigue on plantar pressure distribution of healthy male college students and provide a theoretical basis for improving their awareness of foot health. Methods: Forty-nine ordinary male college students jogged along the 800-meter runway to moderate fatigue. All the subjects took off their shoes and socks and walked naturally with their usual gait. The dynamic plantar pressure of each foot was measured twice in one step. FootscanUSB2 Belgian flat-plate plantar pressure testing system was used for testing. Results: The average dynamic peak plantar pressure was (206.38 44.59) N for boys, and the changes of AA and CB walking speed in the arch did not change significantly. After fatigue, the peak pressure of FM, AA, RH5 in left foot and FM, AA, CB in right foot decreased significantly (P < 0.05, P < 0.01). The peak time of RH and CB in the left foot was significantly shorter than that before fatigue (P < 0.05, P < 0.01), while FMF, AA, C areas had no significant change but tended to be delayed. There were significant differences in peak force-time between boys’ left and right feet except for the fifth metatarsal bone (P < 0.05). There is a significant difference in the peak force-time between the second and fifth toes of the left foot (P< 0.01), and there is a gender difference in the peak force-time between the second metatarsal and the third metatarsal (P < 0.05). Conclusion: Sports fatigue leads to the decrease of physiological functions such as muscle strength of lower limbs, which leads to the corresponding changes in gait stages, plantar pressure distribution parameters, and foot balance. Level of evidence II; Therapeutic studies - investigation of treatment results.
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Plasilova, Magdalena, Robert Christner, Ronghzi Wu, and Jaroslaw P. Maciejewski. "A Pilot Application of SELDI Mass Spectrometry To Study Proteomic Patterns in Plasma from Patients with T-Cell Large Granular Lymphocyte Leukemia." Blood 104, no. 11 (November 16, 2004): 3869. http://dx.doi.org/10.1182/blood.v104.11.3869.3869.
Повний текст джерелаАнотація:
Abstract T-cell large granular lymphocyte (T-LGL) leukemia is a rare chronic lymphoproliferative disorder of cytotoxic T cells of unknown etiology. Chronic antigenic stimulation of T-lymphocytes in autoimmune diseases or viral infection has been postulated to play a role in the pathogenesis of this condition. Surface-enhanced laser desorption/ionization (SELDI) mass spectrometry of plasma and serum specimens was applied as a useful screening method to determine pathophysiologic protein/peptide markers, which may be useful in the diagnosis of occult malignancies. In contrast to traditional diagnostic principles, the SELDI method enables screening of protein patterns without knowing the identity of targets. Patterns of up- and down-modulation of peptides and proteins (resulting from the presence of abnormal products of diseased cells, pathogens or immunogenetic factors) may signal various clinical features and diagnostic clues. We used SELDI mass spectrometry to study proteomic patterns in the plasma of patients with T-LGL leukemia. After initial screening and optimization we selected a hydrophobic H4 ProteinChip surface for further systematic screening. Deviation of mass values and peak intensities were <0.5% and <20%, respectively. Reproducibility was monitored by random duplication of samples with an average of 70 peaks per spectrum (mass/charge ratio from 1500–50,000 Da). Our study included plasma samples from 28 LGL patients, 9 patients with idiopathic neutropenia (without the presence of LGL clone) and 36 healthy blood donors. The diagnosis of T-LGL leukemia included the presence of monoclonal TCR rearrangement and flow cytometric detection of abnormal CD8+CD3+CD57+ cell population. Spectra were analyzed using Biomarker Patterns Software, which allows for internal cross validation for the prediction of the accuracy in a blinded test set. To separate LGL patients from patients with chronic neutropenia, intensity cut-off for 2050 Da peak was found in 22/28 LGL patients, resulting in 100% specificity and 67% sensitivity. Based on the intensities of 3 mass peaks (2274, 5870, 2660 Da), the sensitivity and specificity of LGL distinction from healthy controls was 96% and 61%, respectively. By direct digestion with carboxypeptidase Y on the ProteinChip surface, the C-terminal sequence of the 2050 Da mass peak has been identified. From the sequencing analysis and the search in the ExPASy protein database, we concluded that the 2050 Da mass peak corresponded to the fragment of complement C3 precursor. Additional 2 kDa mass peaks may represent various other C3 fragments. Interestingly, the intensity of the mass peak corresponding to the C3 fragments decreased with the application of immunosuppressive therapy when plasma samples from 3 LGL patients were serially analyzed. The pathophysiologic significance of the identified peak remains unclear, but increased expression of the C3 receptor on LGL cells has been reported. Our data in LGL leukemia indicate that SELDI mass spectrometry can be used to identify immune biomarkers for malignant lymphoproliferations.
9
Su, An. "The Transmission Spectrum of Symmetrical Structured One-Dimensional Photonic Crystals of Positive and Negative Materials." Advanced Materials Research 904 (March 2014): 67–70. http://dx.doi.org/10.4028/www.scientific.net/amr.904.67.
Повний текст джерелаАнотація:
The transmission spectrum of symmetrically structured one-dimensional photonic crystal (AB)m(BA)m consisting of positive and negative materials was studied with transfer matrix method theory. The result shows that a single narrow transmission peak constantly appears at the frequency of uneven ω/ω0, while a broad transmission peak appears at the frequency of even ω/ω0. When periodicity m or refractive index nA of Layer A increase, the narrow transmission peaks in the spectrum become sharper and the broad peaks become narrower; as refractive index nB of Layer B rises, all the peaks in the spectrum become broader; and when the thickness dA of Layer A medium thicken, the transmitting peaks move towards alto frequency,while with the thickening of dB of Layer B medium, these peaks move inversely towards low frequency. Furthermore, in these two circumstances, the transmitting peaks at right alto frequency move faster; however, peaks remain unchanged when both dA and dB concurrently thicken. All these optical transmission characteristics of symmetrically structured one-dimensional photonic crystals can offer guidance to designing adjustable super-narrow optical filters, broad band filters and optical switches.
10
Motta, Andréa Rodrigues, Silvana Bommarito, and Brasília Maria Chiari. "Peak nasal inspiratory flow: uma possível ferramenta para a motricidade orofacial?" Revista da Sociedade Brasileira de Fonoaudiologia 15, no. 4 (December 2010): 609–14. http://dx.doi.org/10.1590/s1516-80342010000400023.
Повний текст джерелаАнотація:
Os fonoaudiólogos que atuam no campo da Motricidade Orofacial atendem com frequência, pacientes com obstrução nasal; entretanto, nem sempre o acesso ao profissional responsável pelo diagnóstico otorrinolaringológico é fácil. O Peak Nasal Inspiratory Flow é um instrumento barato, de fácil manuseio, amplamente citado na literatura internacional, que tem por objetivo avaliar a patência nasal. O objetivo do presente estudo foi realizar uma revisão da literatura acerca do Peak Nasal Inspiratory Flow, fornecendo subsídios para reflexões acerca de seu emprego nos distúrbios miofuncionais orofaciais e cervicais. Para tanto, foi realizada uma revisão da literatura nas bases de dados Medline, Cochrane Library, LILACS e SciELO empregando-se os descritores peak, inspiratory, nasal e flow. O Peak Nasal Inspiratory Flow mostrou-se uma técnica simples, barata, validada e com boa reprodutibilidade. Parece, portanto, tratar-se de um instrumento útil para avaliação da patência nasal, apesar de algumas limitações, fornecendo dados complementares ao diagnóstico miofuncional orofacial e cervical. Entretanto, estudos clínicos precisam ser conduzidos para que se comprove ou refute a hipótese.
Дисертації з теми "Da peak"
1
Favinha, Ana Carla Madeira. "Efeitos da aplicação de tape patelar na atividade muscular do quadricipete." Master's thesis, Universidade de Évora, 2013. http://hdl.handle.net/10174/10865.
Повний текст джерелаАнотація:
A aplicação de tape tem sido sugerida como um procedimento profilático nas lesões músculo esqueléticas, cujo efeito mecânico ou propriocetivo contribui para a limitação do movimento ou para o correto posicionamento de uma articulação.
Objetivo: Verificar os efeitos da aplicação de tape patelar em indivíduos assintomáticos ao nível da produção de força máxima (peak torque) e da atividade muscular do quadricipete.
Metodologia: A amostra foi constituída por 15 sujeitos, do género feminino, com média de idades de 20,8 anos e sem sintomas de síndromes patelo femurais. Foi medida a atividade eletromiográfica, através da aplicação de elétrodos de superfície ao nível das porções do reto femural, vasto lateral e vasto medial, com e sem tape ao nível do tendão patelar, durante a execução de 2 protocolos (isométrico com alternância dos graus de flexão do joelho 30º, 50º e 80º e ainda protocolo isocinético à velocidade de 60º/seg.).
Resultados: Não se verificaram diferenças significativas em relação aos valores de peak torque nem de atividade muscular do quadricipete, com a aplicação de tape patelar (p> 0,05) em qualquer dos protocolos estudados.
Conclusões: Estes resultados sugerem que a aplicação de tape patelar parece não ter efeitos em indivíduos assintomáticos; ### Abstract:
The application of tape has been suggested as a prophylactic procedure in musculoskeletal disorders, the effect of mechanical or proprioceptive contributes to the limitation of movement or for the correct positioning of a joint.
Objective: To investigate the effects of application of patellar tape in asymptomatic at the production of maximum strength (peak torque) and quadriceps muscle activity.
Methods: Young healthy women (20,8 years) without patellofemoral pain syndrome. Electromyographic activity was measured by applying surface electrodes at the level of the portions of the rectus femoris, vastus lateralis, vastus medialis with and without patellar tape tendon, while running two protocols (isometric with alternating degrees of flexion of 30 º , 50 º and 80 º knee isokinetic protocol and also the speed of 60 ° / sec. ) .
Results: There were no significant differences in the values of peak torque or quadriceps muscle activity with the application of patellar tape (p > 0.05 ) in any of the studied protocols .
Conclusions: These results suggest that the application of patellar tape performs to have no effects in asymptomatic subjects.
2
Santos, Joseph dos. "Avaliação do débito máximo da tosse (peak cough flow) na doença pulmonar obstrutiva crónica." Master's thesis, Faculdade de Ciências Médicas. Universidade Nova de Lisboa, 2009. http://hdl.handle.net/10362/4865.
Повний текст джерелаАнотація:
Resumo
Objectivos: Avaliação da Tosse em doentes com Doença Pulmonar
Obstrutiva Crónica (DPOC). Identificar e determinar a relação dos factores
preditivos que contribuem para a deterioração da capacidade de tosse nestes
indivíduos.
Tipo de estudo: Estudo observacional descritivo de natureza transversal.
Definição dos casos: Os critérios de diagnóstico da DPOC são o quadro
clínico e o Gold standard para diagnóstico da DPOC – a espirometria.
População-alvo: Todos os utentes com patologia primária de DPOC
diagnosticada que se desloquem ao serviço de função respiratória do Hospital
de Viseu, para realizar provas.
Método de Amostragem: Foi utilizada uma amostra aleatória constituída por
todos os indivíduos, que cumpriram os critérios de inclusão, conscientes e
colaborantes, que aceitaram participar neste estudo.
Dimensão da amostra: Uma amostra de 55 indivíduos que se deslocaram ao
serviço de função respiratória, entre Janeiro e Junho de 2009, para realizar
provas de função respiratória.
Condução do estudo: Os utentes que aceitaram participar neste estudo
foram sujeitos a um questionário de dados clínicos e realizaram 5 testes:
índice de massa corporal (IMC), estudo funcional respiratório e gasometria
arterial, avaliação da força dos músculos respiratórios (PImax e PEmax) e
avaliação do débito máximo da tosse (Peak Cough Flow).
Análise estatística: Foram obtidos dados caracterizadores da amostra em
estudo, sendo posteriormente correlacionado o valor de débito máximo da
tosse (Peak Cough Flow) com os resultados obtidos para as avaliações do
IMC, estudo funcional respiratório, PImax e PEmax, gasometria, avaliação da
capacidade de Tosse e número de internamentos no último ano por
agudização da DPOC. Tendo sido encontrados os valores de correlação entre
o Peak Cough Flow e os restantes parâmetros.
Resultados: Após análise dos resultados, foram obtidos os valores de Peak
Cough Flow para a população com DPOC e verificou-se valores diminuídos em
comparação com os valores normais da população, tendo-se verificado
maiores valores de PCF em indivíduos do sexo masculino, em comparação
aos valores do sexo feminino. Foi analisada a relação entre o PCF e a idade,
peso, altura e IMC, não tendo sido encontrada relação, dado que a tosse não
apresenta uma variação segundo os valores antropométricos, tal como a
relação com os valores espirométricos. Quanto aos parâmetros funcionais
respiratórios foram analisadas as relações com o PCF. Verificou-se relações
significativas entre o PCF e o FEV1, a FVC, o PEF, apresentando uma relação
positiva, onde maiores valores destes parâmetros estão correlacionados com
maiores picos de tosse. Quanto a RAW e RV, o PCF apresenta uma relação
negativa, onde uma maior resistência da via aérea ou doentes mais
hiperinsuflados leva a menores valores de PCF. Por outro lado não foi
encontrada relação entre o PCF e a FRC e o TLC. Quanto à força dos
músculos respiratórios, verificou-se relação significativa com o PImax e a
PEmax em que a fraqueza ao nível dos músculos respiratórios contribuem
para um menor valor de PCF. Relativamente aos valores da gasometria
arterial, verificou-se relação entre o PCF e a PaO2 de forma positiva, em que
doentes hipoxémicos apresentam menores valores de tosse, e a PaCO2, de
forma negativa, em que os doentes hipercápnicos apresentam menores
valores de PCF tendo sido verificada relação entre o PCF e o pH e sO2.
Quanto à relação entre o número de internamentos por agudização da DPOC
no último ano e o PCF verificou-se uma relação significativa, onde um menor
valor de PCF contribui para uma maior taxa de internamento por agudização
da DPOC.
Conclusão: Este conjunto de conclusões corrobora a hipótese inicialmente
formulada, de que o Peak Cough Flow se encontra diminuído nos indivíduos
com Doença Pulmonar Obstrutiva Crónica onde a variação do PCF se
encontra directamente relacionada com os parâmetros funcionais respiratórios,
com a força dos músculos respiratórios e com os valores de gasometria
arterial. ABSTRACT:
Aims: Cough evaluation in Chronic Obstructive Pulmonary Disease (COPD)
patients. Identify and determine the relation of the predictive factors that
contribute to the cough capacity degradation in this type of patients.
Type of study: Descriptive observational study of transversal nature.
Case definition: The COPD diagnosis criteria are the clinical presentation and
the gold standard to the COPD diagnosis- the Spirometry.
Target Population: Every patients, with primary pathology of COPD
diagnosed, who went to the respiratory function service of Viseu hospital to
perform tests.
Sampling Method: It was used a random sample constituted by all the,
conscious and cooperating individuals, who complied with the inclusion criteria
and who accepted to make part of this study.
Sample size: A sample of 55 individuals that went to the respiratory function
service between January and June 2009 to perform respiratory function tests.
Study: The patients who accepted to make part of this study were submitted to
a clinical data questionary and performed 5 tests: body mass index (BMI),
respiratory functional study, arterial blood gas level, evaluation of respiratory
muscles strength (maximal inspiratory pressure (MIP) and maximum expiratory
pressure (MEP)), and Peak Cough Flow evaluation.
Statistic Analysis: Were obtained characterizing data of the sample in study,
and later correlated the value of the Peak Cough Flow with the results from the
evaluation of the body mass index (BMI), the respiratory functional study the
MIP and MEP, the arterial blood gas level and also with the ability to cough
evaluation and the number of hospitalizations in the last year for COPD
exacerbations. The values of correlation between the Peak Cough Flow and
the other parameters were found.
Results: After analyzing the results, were obtained the values of Peak Cough
Flow for the population with COPD. There were decreased values compared with the population normal values, having been found higher values of PCF in males compared to female values. It was analyzed the relation between the PCF and the age, weight, height and BMI but no relation was found on account
of the fact that the cough does not show a variation according to anthropometric parameters, such as the relation with spirometric values. As for the respiratory functional parameters were analyzed relations with the PCF.
There were significant relations between the PCF and FEV1, the FVC, the PEF,
presenting a positive relation, where higher values of these parameters are
correlated with higher incidence of cough. Concerning the RAW and RV, the
PCF has a negative relation, in which a higher airway resistance or in more
hyperinflated patients, leads to lower values of PCF. On the other hand no
correlation was found between the PCF and the FRC and TLC. Regarding the
respiratory muscle strength, there was a significant relation with the MIP and
MEP, in which the weakness at the level of respiratory muscles contribute to a
lower value of PCF. For values of arterial blood gas level, there was no relation
between the PCF and PaO2, in a positive way, in which patients with hypoxemia present lower values of cough, and PaCO2, in a negative way in which hypercapnic patients had lower values of PCF, having being founded a relation between the PCF and the pH and sO2. As for the relation between the
number of hospitalizations for COPD exacerbation in the last year and the PCF
was found a significant relation, in which a smaller value of PCF contributes to a higher rate of hospitalization for COPD exacerbation.
Conclusion: This set of findings supports the hypothesis first formulated that
Peak Cough Flow is decreased in individuals with Chronic Obstructive Pulmonary Disease, in which the variation of the PCF is directly related to the respiratory function parameters, the strength of respiratory muscles and the values of arterial blood gases.
3
Weaver, Robin Bryn. "The Neolithic of the Peak District : a Lefebvrian social geography approach to spatial analysis." Thesis, University of Birmingham, 2013. http://etheses.bham.ac.uk//id/eprint/4632/.
Повний текст джерелаАнотація:
In this thesis I construct, implement and evaluate a Lefebvrian model of space and society suitable for archaeology, using the Neolithic Peak District as my case study. Archaeologists have largely overlooked the work of French Marxist philosopher and social theorist Henri Lefebvre or come to it second-hand, meaning that his dialectical model of the production of space has never been used to understand prehistoric society. My thesis demonstrates the value to archaeology of such an approach by applying Lefebvre’s three-part dialectical model of the production of space to the monuments and landscape of the Neolithic Peak. In doing so, it challenges simplistic binary readings of social space, replacing them with a Lefebvrian social geography approach to space. Not only does this reveal previously hidden facets of Neolithic society and architecture in the Peak, but my research also provides the first detailed study of this subject in some years. It highlights inter-regional connections between the Peak and other parts of the UK, and illustrates the sheer wealth and diversity of Neolithic monuments in the region, which until now have been sorely neglected. One of its central achievements is to introduce the ‘cross-fertilisation’ monument as a novel class of structure.
4
Lima, Manoel Carlos Spiguel. "Padronização do teste de corrida atada em velocistas : análise da relação entre potência e desempenho em corrida /." Rio Claro : [s.n.], 2007. http://hdl.handle.net/11449/87478.
Повний текст джерелаАнотація:
Orientador: Claudio Alexandre GobattoBanca: Sergio Augusto Cunha
Banca: Pedro Balikian Junior
Resumo: Dentro do âmbito do treinamento competitivo evidencia-se a necessidade de criar e aperfeiçoar testes que possam ser aplicados no próprio ambiente de treinamento, priorizando a busca da especificidade na avaliação e de variáveis que possam melhor explicar as alterações do desempenho do atleta. Então, surge uma problemática ao avaliar a aptidão anaeróbia em velocistas em função das metodologias e dos protocolos propiciarem difícil aplicação e inespecificidade, principalmente por não possuírem nenhum teste com o movimento específico para esse grupo. Entretanto, destaca-se na literatura alguns testes laboratoriais utilizados para avaliação da aptidão anaeróbia de corredores, dentre os quais estão o Máximo Déficit de Oxigênio Acumulado (MAOD), o teste de Wingate (TW) e os testes de salto vertical (SV). Com isso, o objetivo do estudo foi padronizar o teste de corrida atada (TCA) analisando a validade, reprodutibilidade e confiabilidade. O protótipo criado para o TCA proporciona a obtenção de valores de força e de velocidade durante o teste que, por sua vez, fornecerá parâmetros de potência pico do TCA (PPTCA), potência média do TCA (PMTCA) e do índice de fadiga do TCA (IFTCA). Para tanto, 10 velocistas do sexo masculino (22,0 l 2,8 anos; 68,1 l 8,9 kg; 1,76 l 0,09 m; 8,1 l 3,1 % Gordura) participaram do estudo. Todos os participantes foram submetidos a avaliação antropométrica, teste incremental para determinação do consumo máximo de oxigênio (VO2max) e do limiar anaeróbio (LAn), teste para determinação do MAOD, TW, dois TCA (teste e re-teste) e um esforço máximo na distância de 300 metros (D300m). Através de coletas sangüíneas retirada do lóbulo da orelha após os testes de TW, TCA e D300m, foram determinadas as concentrações pico de lactato sangüíneo ([Lac]p) para cada um dos testes, respectivamente... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: In the competitive training area, it is observed the necessity to create and improve tests that could be applied in its own training environment, prioritizing the search of the specificity in the evaluation and the variables that can explain the changes of the athletes performance better. So, we find a problem concerning the anaerobic fitness evaluation in sprinters due to the methodologies and the protocols, mainly because there are no tests with the specific movement for this particular group. However, it is possible to mention some laboratorial tests that are used to verify the anaerobic fitness performance of the runners, which are, the maximal deficit oxygen accumulated (MAOD), the Wingate test (TW) and the tests of vertical jump (VJ). Thereby, the aim of this study is to standardize the tied running test (TRT), analyzing the validity, reproducibility and reliability. The TRT prototype provides the instantaneous strength and speed values during the test that give peak power (PPTRT), mean power (PMTRT) and fatigue index (FITRT) parameters. Therefore, ten male runners (22.0l2.8 years old, 68.1l8.9 kg, 1.76l0.09 m; 8.1l3.1 % Fat) participated in this study. All the subjects were submitted into the anthropometric assessment, incremental test to determination the maximal consume of oxygen (VO2max) and anaerobic threshold (AT), the MAOD determination test, the TW, the two TRT (test and re-test) and maximum effort in 300 meters of distance (D300m). Through blood samples removed from the earlobe after the TW, TRT and D300m tests, the blood peak lactate concentration ([Lac]peak) was determined in each test, respectively, [Lac]peakTW, [Lac]peakTRT and [Lac]peakD300m. The tests were separated with intervals of 24 to 72 hours. The data were presented in mean and stand deviation (M l SD)...(Complete abstract click electronic access below)
Mestre
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Dicken, Craig Arthur. "Settlement, landscape and identity in medieval royal forests : the impact of forest law on Sherwood and the Peak, c. AD 650 to 1348." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/51926/.
Повний текст джерелаАнотація:
This research looks to present a reinterpretation of medieval forests, the least well understood landscapes of medieval Western Europe. The thesis focuses on the Forest of High Peak and Sherwood Forest and seeks to address several key themes, including the diversity of forest landscapes, the long-term impact of Forest Law, and evidence for power-relations and social dynamics within the forests. A wide variety of sources are utilised within this research, including map analysis and regression techniques, analysis of material culture, documentary sources, place names, church architecture, and funerary monuments. Evidence is found for forests having had a dynamic landscape character, including not only woodland, but also moorland, farmland, industrial areas, and urban areas, as well as a range of human activities that included mining, glass and charcoal manufacture, ironworking, leatherworking, carpentry, construction, and intensive arable and pastoral farming. Far from being universally oppressive, it emerges that through its protection of woodland Forest Law also preserved common rights and areas of royal demesne, the impact of which was a high degree of peasant agency during the medieval period.
6
Murata, Helio Massaharu. "Aplicação do GEANT4 no estudo da influência da rugosidade da superfície de ânodos de tubos de raios X utilizados em radiologia diagnóstica." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/43/43134/tde-10062008-142734/.
Повний текст джерелаАнотація:
Estudos recentes utilizaram filtração com absorvedores de W para representar o efeito da rugosidade do ânodo. Para verificar a validade desta metodologia, neste trabalho, foram avaliados espectros de energia na faixa utilizada em radiologia diagnóstica convencional (40, 80 e 150 kV), gerados por tubos de raios X com ânodos rugosos por meio de simulações baseadas no Método de Monte Carlo. Para isto, foi desenvolvido um programa computacional com a ferramenta GEANT4, a qual simula a interação da radiação com a matéria. Neste programa, foram abordados: a modelagem geométrica do sistema, os processos físicos envolvidos e a aplicação de uma técnica de redução de variância baseada no fracionamento (splitting) de bremsstrahlung. Para a modelagem geométrica, as superfícies rugosas dos ânodos foram geradas a partir de um modelo estocástico de crescimento baseado na equação de Edwards-Wilkinson. Os ânodos foram modelados com um ângulo fixo de 16º e de material constituído de 95% de tungstênio e 5% de rênio. As superfícies dos ânodos foram geradas com rugosidades de 0,0; 0,5; 1,0; 2,0; 3,0; 4,0; 5,0 e 6,0 ?m. Também foi realizada a caracterização do feixe de radiação X pelos parâmetros da energia média e da camada semi-redutora (CSR). Estes parâmetros foram calculados numericamente a partir dos espectros de raios X gerados por simulação de Monte Carlo. Os valores das energias médias sofreram aumentos da ordem de 20 a 30% e as CSR\'s entre 11 a 25% aproximadamente, com o aumento das rugosidades, dependendo da energia máxima do espectro. A comparação entre os espectros produzidos com ânodo rugoso e os espectros gerados com a adição de filtração de W no feixe primário de radiação X mostraram que ambos alteram a forma da distribuição espectral, porém de modos distintos. Ou seja, o efeito da rugosidade é diferente do efeito da filtração.Recent studies employed the filtration with tungsten absorbers to represent the effect of the anode roughness. To verify the validity of this method, in this work, the Monte Carlo method was used to simulate the spectra of X rays employed in conventional radiodiagnostics (40, 80 and 150 kV), generated by anode roughness. To perform this task, a computational program was developed with the GEANT4 toolkit, which simulates the interaction of radiation with matter. In this program, the geometric modeling of the system, the relevant physical processes and the application of a variance reduction technique based on bremsstrahlung splitting were implemented. In the geometric modeling, the rough surfaces of the anodes were generated from a stochastic model of roughness growth based on the Edwards-Wilkinson equation. The anodes were modeled with a fixed angle of 16º and material consisting of 95% tungsten and 5% of rhenium. The anode surfaces were generated with roughness of 0.0, 0.5, 1.0, 2.0, 3.0, 4.0, 5.0 and 6.0 ?m. The X ray spectra were characterized by the half-value layers (HVL) and mean energies. These parameters were calculated numerically from X ray spectra generated by the Monte Carlo simulation. The increase in the mean energy values was of the order of 20 to 30% and in the HVLs between 11 and 25% approximately growing with the roughness, depending on maximum energy of the spectrum. Comparison between spectra from anodes with roughness and spectra generated by adding tungsten filtration on primary X ray beam showed that both change the shape of the spectral distribution, but in different ways. In other words, the roughness effect and the filtration effect are not equivalent.
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Vercese, Francine [UNESP]. "Efeito da temperatura sobre o desempenho e a qualidade dos ovos de codornas japonesas." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/95299.
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vercese_f_me_botfmvz.pdf: 499084 bytes, checksum: e9070bee19e12429c7bbf0b7cc0adb1f (MD5)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Universidade Estadual Paulista (UNESP)
Com o objetivo de avaliar o efeito da temperatura sobre o desempenho e qualidade de ovos de codornas japonesas foi realizado um experimento utilizando-se 480 aves na fase de pós-pico de produção. As aves foram alojadas em uma câmara bioclimática com controle automático de temperatura, contendo duas baterias compostas de cinco andares e dez gaiolas, com capacidade para 24 aves cada gaiola, divididas em dois grupos: 240 aves no grupo controle (21°C) e 240 aves no grupo experimental, com temperaturas contínuas de 24, 27, 30, 33 e 36°C em períodos de 14 dias. O período experimental, com duração de 105 dias, foi dividido em cinco ciclos de 21 dias (um ciclo para cada temperatura), sendo 14 dias na temperatura teste e sete dias na temperatura termoneutra. No final de cada ciclo experimental foi avaliado o desempenho e a qualidade dos ovos. Para todos os tratamentos, as rações foram isonutritivas e isocalóricas. Para a avaliação do desempenho e da qualidade dos ovos utilizou-se um delineamento inteiramente casualisado com dois tratamentos (temperatura termoneutra e temperatura teste) e dez repetições de 24 aves por parcela. A elevação da temperatura piora o consumo de ração, reduz o peso dos ovos, a produção e a massa de ovos. Em temperaturas superiores a 27°C houve piora na qualidade interna e externa dos ovos.
In order to evaluate the effect of temperature on performance and egg quality of Japanese quails was conducted an experiment using 480 birds in the post-peak production. The birds were housed in a climate chamber with automatic temperature control, with two batteries composed of five floors and ten cages for up to 24 birds in each cage, divided into two groups: 240 birds in the control group (21oC) and 240 birds in the experimental group, which temperatures of 24, 27, 30, 33 and 36°C. The experiment, lasting 105 days, was divided into five 21-day cycles (one cycle for each temperature), and 14 days at test and seven days a thermoneutral. At the end of each experimental cycle was evaluated performance and egg quality. For all treatments, the diets were isocaloric and isonutritives. For the evaluation of performance and quality of eggs used a completely randomized design with two treatments (temperature and thermoneutral temperature test) and ten replicates of 24 birds per plot. Elevated temperature worsens the feed intake, egg weight, production and egg mass. At temperatures above 27°C worsened the internal and external quality of eggs.
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Carvalho, Sérgio Manuel de Seixas. "Estudo comparativo da força muscular isocinética dos flexores e extensores do joelho em atletas praticantes de Futebol e Futsal." Bachelor's thesis, [s.n.], 2010. http://hdl.handle.net/10284/8365.
Повний текст джерелаАнотація:
Monografia apresentada à Universidade Fernando Pessoa para obtenção do grau Licenciado em FisioterapiaApesar das diversas similitudes inerentes ao futebol e ao futsal, cada modalidade apresenta características próprias em termos de habilidades e tipologia de esforço. Posto isto, o objectivo do presente estudo é traçar o perfil muscular de jogadores de ambas as modalidades relativamente aos músculos extensores (quadricipede) e flexores (isquio-tibiais) da articulação do joelho, através da análise do peak torque, trabalho e relação agonista/antagonista. Para tal, participaram no estudo 16 atletas, sendo 8 de futebol e 8 de futsal. A média de idade dos jogadores foi de 23,5 anos_ Os resultados encontrados neste estudo demonstram que não existem diferenças significativas entre membro inferior dominante e não dominante para cada das variáveis estudadas_ Observam-se diferenças significativas em termos de Peak torque aos 60°/s entre os atletas das duas modalidades estudadas, assim como do Total work do MID à mesma velocidade. Os resultados obtidos aos 180°/s sugerem superioridade em termos de Peak torque do MIE para os atletas de Futebol e, para a mesma velocidade, os atletas de Futebol também apresentam maior capacidade de produção de trabalho total. Para o RI/Q não é de salientar diferenças significativas, deste modo, todos os valores encontrados situam-se entre 50 a 60% a baixa velocidade angular, sendo considerados valores normais. Em termos globais, os atletas de futebol deste estudo parecem demonstrar uma relativa superioridade quando comparados com atletas de futsal no que concerne ao perfil muscular extensor e flexor do joelho.
Despite several similarities inherent to football and futsal, each modality has its own characteristics in terms of skills and type of effort. This way, the aim of this study is to perform a muscular profile of the players of both modalities for the extensor muscles (quadriceps) and flexors muscles (ischiotibialis) of the knee joint through the analysis of peak torque, total work and agonist / antagonist ratio, 16 athletes took part in the study, 8 of each modality. The mean age of the group was 23.5 years_ The results found in this study demonstrate that there are no significant differences between dominant and non-dominant leg for each of the studied variables. it was observed significant differences in terms of peak torque at 60 Vs between the athletes of the two modalities, as well as the total work of the right leg at the same speed. Results at 180°/s suggest some degree of superiority in terms of left leg peak torque for football athletes. Football athletes also seems to present better skills for total work production, at the same speed_ For the agonist/antagonist ratio, there is no significant differences, thus all values were found between 50-60%, at low angular velocity, what can be considered as normal. Overall, the soccer athletes in this study appear to demonstrate a relative superiority when compared to futsal players in relation to the muscle profile of the knee.
N/A
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Mahunguana, Manuel José. "Efeito da discretização espaço-temporal no manejo de águas pluviais." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2014. http://hdl.handle.net/10183/98147.
Повний текст джерелаАнотація:
Os custos econômicos e perdas potenciais de vidas humanas resultantes de falhas em sistemas de drenagem de águas pluviais podem ser enormes, aumentando a necessidade da busca de melhores métodos de dimensionamento destes. Os métodos baseados na precipitação de projeto são os mais usados para a estimativa do hidrograma de projeto em bacias urbanas, devido às facilidades que os mesmos apresentam em relação aos outros métodos. Entretanto, estes métodos têm suas limitações e incertezas, que podem influenciar as características do hidrograma de projeto resultante, incertezas que são, em consequência, transferidas ao dimensionamento hidráulico das obras propostas. No presente trabalho, foram avaliados os efeitos da discretização espacial da bacia, da discretização temporal e da posição do pico do hietograma de projeto, sobre as principais características do hidrograma de projeto. Esses efeitos foram ainda avaliados no dimensionamento hidráulico do sistema de macrodrenagem dos bairros de Mavalane “A” e Maxaquene “A”, localizados na cidade de Maputo em Moçambique. Para avaliar os referidos efeitos, a bacia foi discretizada em 1, 5, 7 e 12 sub-bacias. O intervalo de tempo do hietograma de projeto foi discretizado em 1, 2, 3, 4 e 5 minutos, sendo calculados para cada discretização e intervalo de tempo, hietogramas com pico no início, 25%, 50%, 75% e final do evento com duração correspondente a 90 minutos e 24 horas. Os hietogramas foram transformados em vazão no programa IPHS1, a qual foi propagada no sistema de macrodrenagem usando o modelo EPA SWMM 5.0, sendo obtidos os hidrogramas de projeto resultantes. O exutório da bacia e o trecho C19 localizado na região central da bacia foram escolhidos para análise dos resultados. Os resultados obtidos mostram uma influência importante dos efeitos avaliados nas características do hidrograma de projeto: vazão de pico, tempo de pico e volume parcial e, consequentemente, no dimensionamento da rede de macrodrenagem, sendo o efeito da discretização da bacia o mais influente, seguido dos efeitos da posição do pico da chuva e intervalo de tempo.The economic costs and potential losses of human lives due to failure in stormwater drainage systems can be significant, calling for an improvement in methods used for its design. The design storm approach, also known as “single-event design-storm” is widespread used in formulating design hydrograph from historical rainfall data in urban watersheds, due to its relative advantages when compared to other methods. Therefore, this approach has its uncertainties which can affect the resulted design hydrograph, and consequently affect the hydraulic design of proposed structures. In this study is presented an assessment of the adopted values in design criteria, during the estimation of design hydrograph used in hydraulic design of stormwater drainage systems. In particular, are assessed the effects of spatial discretization of the watershed, the temporal discretization and peak position of the design hyetograph, in the main features of the resulted design hydrograph. The same effects are then assessed in the hydraulic design of the major stormwater drainage system of Mavalane “A” and Maxaquene “A” neighborhoods, located in Maputo city in Mozambique. To assess these effects, the watershed was discretized into 1, 5, 7 and 12 sub-watersheds. The time step of the design hyetograph was discretized into 1, 2, 3, 4 and 5 minutes, and then computed for each discretization and time step, hyetographs with peak positioned in the beginning, 25%, 50%, 75% and the end of the duration of 90 minutes and 24 hours. The hyetographs were converted into runoff in IPHS1, wish was dynamically routed in the drainage system, using EPA SWMM 5.0. The watershed outlet and conduit C19 were used to analyze the results. The results show an important influence of the assessed effects on the design hydrograph features: hydrograph peak, time to peak and partial volume and, consequently, on the hydraulic design of the major stormwater drainage system, being the effect of spatial discretization of the watershed, the most important, followed by hyetograph peak position and time step.
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Lima, Manoel Carlos Spiguel [UNESP]. "Padronização do teste de corrida atada em velocistas: análise da relação entre potência e desempenho em corrida." Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/87478.
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lima_mcs_me_rcla.pdf: 2267744 bytes, checksum: 3e5de7b75b382e805164ebdf2da33ff5 (MD5)Dentro do âmbito do treinamento competitivo evidencia-se a necessidade de criar e aperfeiçoar testes que possam ser aplicados no próprio ambiente de treinamento, priorizando a busca da especificidade na avaliação e de variáveis que possam melhor explicar as alterações do desempenho do atleta. Então, surge uma problemática ao avaliar a aptidão anaeróbia em velocistas em função das metodologias e dos protocolos propiciarem difícil aplicação e inespecificidade, principalmente por não possuírem nenhum teste com o movimento específico para esse grupo. Entretanto, destaca-se na literatura alguns testes laboratoriais utilizados para avaliação da aptidão anaeróbia de corredores, dentre os quais estão o Máximo Déficit de Oxigênio Acumulado (MAOD), o teste de Wingate (TW) e os testes de salto vertical (SV). Com isso, o objetivo do estudo foi padronizar o teste de corrida atada (TCA) analisando a validade, reprodutibilidade e confiabilidade. O protótipo criado para o TCA proporciona a obtenção de valores de força e de velocidade durante o teste que, por sua vez, fornecerá parâmetros de potência pico do TCA (PPTCA), potência média do TCA (PMTCA) e do índice de fadiga do TCA (IFTCA). Para tanto, 10 velocistas do sexo masculino (22,0 l 2,8 anos; 68,1 l 8,9 kg; 1,76 l 0,09 m; 8,1 l 3,1 % Gordura) participaram do estudo. Todos os participantes foram submetidos a avaliação antropométrica, teste incremental para determinação do consumo máximo de oxigênio (VO2max) e do limiar anaeróbio (LAn), teste para determinação do MAOD, TW, dois TCA (teste e re-teste) e um esforço máximo na distância de 300 metros (D300m). Através de coletas sangüíneas retirada do lóbulo da orelha após os testes de TW, TCA e D300m, foram determinadas as concentrações pico de lactato sangüíneo ([Lac]p) para cada um dos testes, respectivamente...
In the competitive training area, it is observed the necessity to create and improve tests that could be applied in its own training environment, prioritizing the search of the specificity in the evaluation and the variables that can explain the changes of the athlete s performance better. So, we find a problem concerning the anaerobic fitness evaluation in sprinters due to the methodologies and the protocols, mainly because there are no tests with the specific movement for this particular group. However, it is possible to mention some laboratorial tests that are used to verify the anaerobic fitness performance of the runners, which are, the maximal deficit oxygen accumulated (MAOD), the Wingate test (TW) and the tests of vertical jump (VJ). Thereby, the aim of this study is to standardize the tied running test (TRT), analyzing the validity, reproducibility and reliability. The TRT prototype provides the instantaneous strength and speed values during the test that give peak power (PPTRT), mean power (PMTRT) and fatigue index (FITRT) parameters. Therefore, ten male runners (22.0l2.8 years old, 68.1l8.9 kg, 1.76l0.09 m; 8.1l3.1 % Fat) participated in this study. All the subjects were submitted into the anthropometric assessment, incremental test to determination the maximal consume of oxygen (VO2max) and anaerobic threshold (AT), the MAOD determination test, the TW, the two TRT (test and re-test) and maximum effort in 300 meters of distance (D300m). Through blood samples removed from the earlobe after the TW, TRT and D300m tests, the blood peak lactate concentration ([Lac]peak) was determined in each test, respectively, [Lac]peakTW, [Lac]peakTRT and [Lac]peakD300m. The tests were separated with intervals of 24 to 72 hours. The data were presented in mean and stand deviation (M l SD)...(Complete abstract click electronic access below)
Книги з теми "Da peak"
1
Hobbin, Agnes. A peerie peek at da past. Lerwick: Shetland Times, 2000.
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2
Zašto mislim da je danas petak. Zagreb: Sarajevo, 2019.
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3
Da Twin Peaks a Twin Peaks: Piccola guida pratica al mondo di David Lynch. Sesto San Giovanni (MI): Mimesis, 2015.
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4
Marino, Matteo. Il mio primo dizionario delle serie TV cult: Da Twin peaks a Big band theory. Padua]: BeccoGiallo, 2016.
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5
Estes, Ricardo. Asthma Journal - Eat Sleep Crush Crohn's Disease Repeat Survivor Family: Crush Crohn's Disease, Asthma Symptoms Tracker with Medication,Peak Flow Meter Section and Exercise Tracker Organizer, Triggers,Symptoms Tracker for People with Asthma ,Da. Independently Published, 2021.
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6
Hubbard, Karla. Asthma Journal - Eat, Sleep, Fix Stuff, Repeat! Gift for Repairman, Handyman Pretty: Fix Stuff, Asthma Symptoms Tracker with Medication,Peak Flow Meter Section and Exercise Tracker Organizer, Triggers,Symptoms Tracker for People with Asthma ,Da. Independently Published, 2021.
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7
Charles, Watkins. Asthma Journal - Eat Sleep Buy Crypto Repeat Bitcoin Blockchain Crypto Defi Saying: Buy Crypto, Asthma Symptoms Tracker with Medication,Peak Flow Meter Section and Exercise Tracker Organizer, Triggers,Symptoms Tracker for People with Asthma ,Da. Independently Published, 2021.
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Bonilla, Maysa. Asthma Journal - Eat Sleep Car Tuning Repeat Car Mechanics Gift Car Tuning Graphic: Car Tuning, Asthma Symptoms Tracker with Medication,Peak Flow Meter Section and Exercise Tracker Organizer, Triggers,Symptoms Tracker for People with Asthma ,Da. Independently Published, 2021.
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9
Manual De Publicaciones De La American Psychological Association Traduccin Puesta Al Da Por Miroslava Guerra Fras Revisin Y Adaptacin Lingistica Silvia Rosa Pea Alfaro Gonzlez Editor Responsable Santiago Viveros Fuentes. American Psychological Association (APA), 2010.
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1
Albin, Roger L. "Pharmacology I." In Parkinson Disease, 223–36. Oxford University PressNew York, 2022. http://dx.doi.org/10.1093/med/9780190843014.003.0012.
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Abstract Pharmacotherapy is the cornerstone of management for Parkinson disease (PD). Pharmacotherapy is the most impactful intervention, and other treatment modalities generally work best in conjunction with judicious pharmacotherapy. Pharmacotherapy is primarily symptomatic dopamine (DA) replacement therapy (DRT) with L-dopa preparations, adjuncts to L-dopa preparations, and/or DA agonists. L-dopa preparations continue to be the best treatment for PD. This chapter reviews the fundamentals of dopaminergic neurotransmission, and L-dopa pharmacokinetics and pharmacodynamics. The potential mechanism of peak dose dyskinesias is reviewed, as are the interactions of disease progression with L-dopa pharmacokinetics and pharmacodynamics.
2
Lousada, Sérgio António Neves, Leonardo Gonçalves, and Erdem Kaya. "Hydraulic Planning in Insular Urban Territories." In Analyzing Sustainability in Peripheral, Ultra-Peripheral, and Low-Density Regions, 81–103. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-6684-4548-8.ch005.
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This study aims to examine the flood propensity of the main watercourse of Porto da Cruz drainage basin and, if relevant, to propose two methodologies to alleviate the impacts (i.e., detention basin sizing and riverbed roughness coefficient adjustment). Geomorphological data were obtained from the watershed characterization process and used through the SIG ArcGIS software for the flood propensity assessment and then for the calculation of the expected peak flow rate for a return period of 100 years through the Gumbel Distribution. Subsequently, the drainage capacity of the river mouth was verified using the Manning‐Strickler equation in order to establish whether the river mouth of the watershed has the capacity to drain the entire volume of rainwater in a severe flood event. In conclusion, the results demonstrate that the river mouth of the Porto da Cruz watershed does not have the capacity to drain the rain flow for the predetermined return period; thus, the detention basin was sized through the Dutch method and the simplified triangular hydrograph method.
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Praxedes, Jomilto. "O USO DA AVALIAÇÃO MORFOLÓGICA E MOTORA PARA O PLANEJAMENTO DE EXERCÍCIOS FÍSICOS DE CRIANÇAS." In EDUCAÇÃO E FORMAÇÃO EM SAÚDE: PRÁTICAS PARA CONSTRUÇÃO DE UM CONHECIMENTO EDIFICANTE. Literacia Cientifica Editora & Cursos, 2022. http://dx.doi.org/10.53524/lit.edt.978-65-995572-3-1/04.
Повний текст джерелаАнотація:
OBJECTIVE: The present study aims to present the relevance of anthropometric and motor assessment in the development of a physical exercise program for school-age children. MATERIALS AND METHODS: The present research was carried out through a narrative literature review, with an electronic search of complete scientific articles, written in Portuguese and English. RESULTS AND DISCUSSION: Regarding the anthropometric assessment, variables such as body mass index and peak growth velocity can be used to monitor children's health status, growth process and development. In motor assessment, tests such as the Körperkoordination Test fur Kinder (KTK), Motorische Basiskompetenzen (MOBAKs), Test of Gross Motor Development (TGMD), Movement Assessment Battery for Children Test (MABC), are used to determine the level of motor competence of the children. children. It is understood that the assessment is not just to measure or classify children, but a case of public health. FINAL CONSIDERATIONS: Information from the assessments allows for greater physical, motor and maturational knowledge of each child, which will be important for the development of physical exercise programs aimed at improving motor competence, reducing the risk of childhood obesity and increasing quality of life.
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Mello, Mariana Neves Cruz, Andreza Lima Araújo, and Carolina do Socorro Ferreira Magalhães. "FORÇA, RAÇA E GANA SEMPRE! O PAPEL DA LIDERANÇA E DO PROTAGONISMO FEMININO PARA A CONSOLIDAÇÃO DO MOVIMENTO POPULAR MOEDA VERDE EM IGARAPÉ AÇU (PA)." In Política, ecologia e (re)existência na Amazônia brasileira: um outro (des)envolvimento é possível, 110–29. Editora Itacaiúnas, 2021. http://dx.doi.org/10.36599/itac-peam.0006.
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Matos, Jefferson David Melo de, Ana Larisse Carneiro Pereira, Leonardo Jiro Nomura Nakano, Guilherme da Rocha Scalzer Lopes, John Eversong Lucena de Vasconcelos, Renato Sussumu Nishioka, Marco Antonio Bottino, and Manoela Capla de Vasconcellos dos Santos da Silva. "POLI-ÉTER-ÉTER-CETONA MODIFICADA (PEEK) COMO OPÇÃO DE BIOMATERIAL PARA AS REABILITAÇÕES ORAIS." In Ciências da Reabilitação, 60–72. Atena Editora, 2019. http://dx.doi.org/10.22533/at.ed.4371906117.
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Silva, Franciele Matos, Danilo Belchior Costa Silva, Luiz Felipe Alves Barcelo, and Edson Alves Figueira Júnior. "PEAD REFORÇADO COM FIBRA DE BAMBU." In Força, Crescimento e Qualidade da Engenharia Civil no Brasil 4, 72–81. Atena Editora, 2021. http://dx.doi.org/10.22533/at.ed.8132109046.
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Assumpção, Willian Rodrigues, and Fabiana Rocha Pinto. "ESTUDO DA PRATICIDADE DE USO: TUBOS PEAD E TUBOS DE CONCRETO EM OBRAS DE DRENAGEM PLUVIAL URBANA." In Da Ferramenta SWOT à Plataforma BIM: Soluções da Engenharia, 71–83. Editora Amazônia Et. Al., 2022. http://dx.doi.org/10.29327/574107.1-6.
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Ramos, Roberto Carlos, Francine Abreu Guerra, and Wanderson Frigotto Fernandes. "IMPACTOS DOS PROJETOS EDUCACIONAIS DA UNESCO (PEA) NO LA SALLE CARMO." In Educação Lassalista: Saberes da prática educativa, 78–89. Atena Editora, 2022. http://dx.doi.org/10.22533/at.ed.2952207019.
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Guerreiro, Rita, and Vanda Cabrinha Pires. "Monitoring Agricultural Drought in Mainland Portugal." In Monitoring and Predicting Agricultural Drought. Oxford University Press, 2005. http://dx.doi.org/10.1093/oso/9780195162349.003.0023.
Повний текст джерелаАнотація:
Mainland Portugal (37°–42°Nlatitude) is located in the transitional region between the subtropical anticyclone and the subpolar depression zones. In addition to latitude, its orography and the effect of the Atlantic Ocean are the major factors affecting the climate of the mainland Portugal. The highest altitudes vary from 1000 m to 1500 m, with the exception of the Serra da Estrela range, whose peak is just below 2000 m. The regions farthest from the Atlantic Ocean are around 220 km away. Portugal has a total area of 9.2 million ha, 41% of which is devoted to cropland. Although agricultural practices in some regions are still traditional and not competitive, they are slowly becoming more and more industrialized and employ about 20% of the active population, which includes employment in agricultural industries as well. The inclusion of Portugal to the European Community in 1986, on the one hand, provided financial resources, but, on the other hand, caused agricultural policy to become more dependent on community policies. Farm size has doubled since the 1970s with increased mechanization. Wine production is the most important agricultural activity, which contributes significantly to Portugal’s economy (GPPAA, 1999). Among fruit trees, apples and citrus fruit have the highest productions, about 250,000 tons and 230,000 tons per year, respectively. Olive trees produce about 40,000 tons of olive oil per year (GPPAA, 1999). Food grain production is relatively low and not enough for domestic use. This is mainly due to the prevailing climate. The Portuguese climate is classified as Mediterranean, with some variations depending on orography and latitude. The annual cycles of monthly mean precipitation and temperature (minimum and maximum) reveal that warm and dry summers are more pronounced in the southern regions. This type of climate presents several drawbacks to agriculture, the major one being insufficient rainfall during the summer or spring seasons (Pinto and Brandão, 2002). Most of the rainfall occurs during winter season, from November until March. The majority of soils in Portugal are badly drained and suffer from water logging during the rainy season. A significant decrease in spring precipitation has been observed for last two decades.
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Sá, Mayelli Dantas de, José William de Lima Souza, Michele Dayane Rodrigues Leite, José Filipe Bacalhau Rodrigues, Hermano de Vasconcelos Pina, and Marcus Vinicius Lia Fook. "AVALIAÇÃO QUÍMICA E BIOLÓGICA DE COMPÓSITOS OBTIDOS A PARTIR DE PEEK/CaCO3." In A Produção do Conhecimento nas Ciências da Saúde, 86–97. Atena Editora, 2019. http://dx.doi.org/10.22533/at.ed.98219300449.
Повний текст джерелаТези доповідей конференцій з теми "Da peak"
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Gao, Weijun, Yi Chen, Chong Han, and Zhi Chen. "Distance-Adaptive Absorption-Peak Hopping (DA-APH) Modulation for Terahertz Covert Communications." In GLOBECOM 2019 - 2019 IEEE Global Communications Conference. IEEE, 2019. http://dx.doi.org/10.1109/globecom38437.2019.9013380.
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Martins, Bruna Nery, Allane C. C. Rodrigues, Arsênio P. V. Neto, Ademir J. Camargo, and Heibbe C. B. de Oliveira. "Estudo dos efeitos da solvatação aquosa na norepinefrina usando Dinâmica Molecular de Car-Parrinello." In VIII Simpósio de Estrutura Eletrônica e Dinâmica Molecular. Universidade de Brasília, 2020. http://dx.doi.org/10.21826/viiiseedmol2020104.
Повний текст джерелаАнотація:
Norepinephrine, synthesized from tyrosine, is a neurotransmitter of sympathetic post-ganglion neurons. Norepinephrine regulates many critical functions which include attention, memory, learning and cardiovascular functions. This neurotransmitter has several pharmacological uses, such as adrenergic stimulants, widely used in the treatment of hypertension, cardiac surgery and in myocardial infarction. It is extremely important to study the interaction between drugs and water molecules, for a better understanding of absorption, transport and biological action. Within this context, the Car-Parrinello Molecular Dynamics, by treating the solvent explicitly, becomes ideal for the study of solvated media. In this sense, the objective of this work is to analyze the effects of aqueous solvation on the geometric and electronic parameters of norepinephrine using the Molecular Dynamics of Car-Parrinelo. The solvation dynamics was performed using the CPMD program package (version 4.1). The Radial Distribution Function of the hydrogen and oxygen atoms of the water molecules in the first solvation shell were performed for the O1, O2, O3, N7, H4, H5, H6, H8 and H9 atoms of the norepinephrine. The Radial Distribution Function analyzes indicate that most sites have a well-defined peak (N7, O1, O3, H4, H5 and H6). For the O2, H8 e H9 atoms, there are no well-defined peaks, suggesting that these sites do not interact with the atoms of the water molecules, or even the possibility of intra-molecular interactions. These criteria were considered for the next stages of this work, which are already being carried out, and they are analyzes of possible interactions of hydrogen with these sites.
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DeMarco, Paul J., Joel Pokorny, and Vivanne C. Smith. "Full-spectrum cone sensitivity functions for anomalous trichromats." In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1990. http://dx.doi.org/10.1364/oam.1990.fm7.
Повний текст джерелаАнотація:
From color matching, subjects with protanomalous (PA) and deuteranomalous (DA) trichromacy appear to have three functional classes of cone photopigment, but the peak absorption of one photopigment, either the M-cone (DA) or the L-cone (PA), occurs at a different wavelength than for normal subjects. Pokorny, Smith and Katz (1973) derived absorption spectra for anomalous photopigments of 500-700 nm by using Schmidt’s (1955) anomaloscope matching data for normal subjects with anomalous trichroma.
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Khan, Tariq Amin, and Wei Li. "Numerical Study on the Performance of a Tube With Inserted Porous Media of Various Thermal Conductivities." In ASME 2016 Heat Transfer Summer Conference collocated with the ASME 2016 Fluids Engineering Division Summer Meeting and the ASME 2016 14th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/ht2016-7056.
Повний текст джерелаАнотація:
Numerical study is performed on the effect of thermal conductivity of porous media (k) on the Nusselt number (Nu) and performance evaluation criteria (PEC) of a tube. Two-dimensional axisymmetric forced laminar and fully developed flow is assumed. Porous medium partially inserted in the core of a tube is investigated under varied Darcy number (Da), i.e., 10−6 ≤ Da ≤ 10−2. The range of Re number used is 100 to 2000 and the conductivity of porous medium is 1.4 to 202.4 W/(m.K) with air as the working fluid. The momentum equations are used to describe the fluid flow in the clear region. The Darcy-Forchheimer-Brinkman model is adopted for the fluid transport in the porous region. The mathematical model for energy transport is based on the one equation model which assumes a local thermal equilibrium between the fluid and the solid phases. Results are different from the conventional thoughts that porous media of higher thermal conductivity can enhance the performance (PEC) of a tube. Due to partial porous media insertion, the upstream parabolic velocity profile is destroyed and the flow is redistributed to create a new fully develop velocity profile downstream. The length of this flow redistribution to a new developed laminar flow depends on the Da number and the hydrodynamic developing length increases with increasing Da number. Moreover, the temperature profile is also readjusted within the tube. The Nu and PEC numbers have a nonlinear trend with varying k. At very low Da number and at a lower k, the Nu number decreases with increasing Re number while at higher k, the Nu number first increases to reach its peak value and then decreases. At higher Re number, the results are independent of k. However, at a higher Da number, the Nu and PEC numbers significantly increases at low Re number while slightly increases at higher Re number. Hence, the change in Nu and PEC numbers neither increases monotonically with k, nor with Re number. Investigation of PEC number shows that at very low Da number (Da = 10−6), inserting porous media of a low k is effective at low Re number (Re ≤ 500) while at high Re number, using porous material is not effective for the overall performance of a tube. However, at a relatively higher Da number (Da = 10−2), high k can be effective at higher Re number. Moreover, it is found that the results are not very sensitive to the inertia term at lower Da number.
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Doryan Hilton Filgueira Bezerra, João Telésforo Nóbrega de Medeiros, Moisés Vieira de Melo, Neil de Oliveira Lima Filho, Danyel Ribeiro Araújo, and Silvio Romero de Melo. "Caracterização do alongamento e da área da seção transversal em PEAD submetido a solicitação axial." In IX Congresso Nacional de Engenharia Mecânica. Rio de Janeiro, Brazil: ABCM Associação Brasileira de Engenharia e Ciências Mecânicas, 2016. http://dx.doi.org/10.20906/cps/con-2016-1327.
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Cezar, Aline, Joyce Azevedo, Carolina Carvalho Simões de Oliveira Motta, and Luciano Pisanu. "Avaliação da Influência da Temperatura e Tempo de Secagem da Casca de Arroz nas Propriedades Mecânicas de Compósitos Poliméricos com PEAD." In X Congresso Nacional de Engenharia Mecânica. ABCM, 2018. http://dx.doi.org/10.26678/abcm.conem2018.con18-0423.
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ANA, MARCIO DE FREITAS SANTA. "FORMAÇÃO DE MEMBRANA PROTÔNICA COM NANOCOMPÓSITOS SULFONADOS DE PS / PEEK / ARGILA MMT E AGENTE INTERFACIAL MB APLICADAS A CÉLULA COMBUSTÍVEL TIPO PEM." In Brazilian Congress. brazco, 2020. http://dx.doi.org/10.51162/brc.dev2020-00022.
Повний текст джерелаАнотація:
Este artigo visa a utilizacao de fontes energeticas sustentaveis tendo como foco a preservacao dos recursos naturais, visando atender a demanda energetica com o minimo de danos ao Meio Ambiente com a obtencao de Nanocompositos a partir da conjugacao dos polimeros comerciais sulfonados PS (poliestireno) PEEK (poli-eter- cetona) com o reforco da argila sulfonada para que a membrana tenha as caracteristicas necessarias para ser aplicadas na PEMFC. A justificativa desta proposta esta baseada na investigacao de que a sulfonacao previa tanto das bases polimericas quanto da argila mineral (Montmorilonita-MMT), utilizados para preparar o nanocomposito pode ser uma alternativa para se conjugar as propriedades que tanto se almeja encontrar nas membranas, isto e, elevada permeabilidade protonica e resistencias termica e mecanica. Em termos economicos, a justificativa esta vinculada a necessidade de reduzir custos de producao e ao mesmo tempo obter membranas com elevadas condutividade e resistencias termicas e mecanicas em linhas gerais, a proposta do artigo tem o objetivo preparar blendas polimericas de alto desempenho baseadas em PEEK e PS com adicao de agente compatibilizante durante o preparo da solucao polimerica de mostrar o desenvolvimento de uma materia-prima alternativa para substituir a membrana utilizada comercialmente. Garantindo a homogeneidade e analisar a confiabilidade das membranas do tipo PEM para utilizacao em celulas combustiveis, baseadas em PEKK E PS com adicao de agente compatibilizante durante o preparo da solucao polimerica, garantindo a homogeneidade, uma vez que requisitos de durabilidade e custo passaram a ser fundamentais a esta tecnologia. A metodologia proposta para o preparo da mistura polimerica foi solubilizar os polimeros SPEEK (poli (eter-eter-cetona) sulfonado), SPS (Poliestireno sulfonado) e 22298-CN - MB (Agente Interfacial) no solvente DMF (Dimetilformamida) em sistema fechado acoplado a um condensador de refluxo, para evitar a evaporacao do solvente, e promover a mistura das bases polimericas e do agente compatibilizante MB no teor de 3 % em peso em relacao a mistura. Os resultados preliminares do grupo de pesquisa indicaram que a mistura sPS/sPEEK apresentou boas caracteristicas protonicas e termicas ,
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Prakash, Raghu V., and Dhinakaran Sampath. "Effect of Hold-Time Interspersed With Cyclic Loading on Corrosion Fatigue Crack Growth Rate of a Steel in Sodium Chloride Solution." In ASME 2018 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/imece2018-86417.
Повний текст джерелаАнотація:
Corrosion fatigue growth behavior of structural steels at low cyclic frequency is characterized by an increase in crack growth rate in the threshold and Paris regions, due to the simultaneous action of cyclic mechanical load (fatigue) and corrosive environment. Knowledge on the effect of load sequence on corrosion fatigue crack growth is important to set out the realistic design and prognosis criteria for components operating under corrosive environments. In this study, the corrosion fatigue crack growth rate under the effect of hold-time (1000s), at a maximum stress intensity factor (Kmax), interspersed during cyclic load on was studied experimentally on a Mn-Ni-Cr steel under 3.5% NaCl solution at a constant stress intensity factor range (ΔK) of 15 MPa √m; the corrosion crack growth rate was evaluated for three different frequencies of: 0.01, 0.1 and 1 Hz. As a result of hold time at the peak load, the exposure time for the crack-tip to interact with the environment increased, which could enhance the corrosion crack growth rates. To verify if this corrosion effect can be contained, electrode potential of (−) 850 mV and (−) 950 mV SCE was applied to the specimen to reduce the extent of corrosion contribution to crack growth rate. The fatigue crack growth rate (da/dN) increased when the frequency was decreased from 1 to 0.01 Hz at all electrode potentials. However, the crack growth rate at 0.01 Hz increased by an order of magnitude with a tensile hold at Kmax for 1000 s compared with the crack growth rate during continuous cyclic load for a given electrode potential. The crack growth rate reduced when the electrode potential was decreased to −950 mV SCE. The enhancement of corrosion fatigue crack growth rate with the introduction of a hold-time is explained using crack-tip strain rate assisted anodic dissolution.
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Mendes, Adriana Cristina dos Santos, SANDRA DE FÁTIMA BARBOZA FERREIRA, CLAUDIA SANTOS GONÇALVES BARRETO BEZERRA, ERICA YAMAUCHI TORRES, and MÍRIAM DO ROCIO GUADAGNINI. "PROGRAMA DE ESTIMULAÇÃO DA ATENÇÃO – PEA NO SUPORTE A ALUNOS COM TDAH." In I Congresso Brasileiro On-line de Pesquisas e Inovação em Educação. Revista Multidisciplinar de Educação e Meio Ambiente, 2022. http://dx.doi.org/10.51189/cinped/13543.
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MARSON, Luigi, and Marcelo MASSARANI. "Estudo da mudança na interface metal-metal para metal - PEEK (Poli-eter-eter-cetona) em componentes de transmissões mecânicas manuais visando o aumento da resistência ao desgaste." In XXV Simpósio Internacional de Engenharia Automotiva. São Paulo: Editora Blucher, 2017. http://dx.doi.org/10.5151/engpro-simea2017-40.
Повний текст джерелаЗвіти організацій з теми "Da peak"
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Kutlu, İhsan. Türki̇ye’de Sağlıkta Özelleşmenin Sonuçları Sağlık Hı̇zmetlerı̇nı̇n Değişen Arz ve Talep Yapısı. İLKE İlim Kültür Eğitim Vakfı, March 2021. http://dx.doi.org/10.26414/pn018.
Повний текст джерелаАнотація:
1980 yılı sonrasında dünyada ve Türkiye’de ağırlık kazanmaya başlayan neoliberal politikalar sağlık sistemini de kapsayacak şekilde hayatın pek çok alanına nüfuz etmiştir. Bu bağlamda tarihsel kökleri daha eski yıllara dayanmakla birlikte ülkemizde özellikle Sağlıkta Dönüşüm Programı çerçevesinde bu politikalar uygulamaya konulmuş ve zaman içerisinde önemli değişimler yaşanmıştır. Sağlık alanında özel sektörün giderek yaygınlık kazanması da yaşanan bu değişimlerden biri olmuştur. Sağlık sisteminin özelleşmesinin rekabete dayalı olarak sağlık hizmeti kalitesinin artması gibi olumlu bazı sonuçları olsa da bu eğilim tekelleşme gibi birtakım riskler de barındırmaktadır. Bu çalışmada sağlık hizmeti verilen kurumlar (hastane sayıları vb.), personel durumu (he-kim-hemşire sayıları) ve sağlık hizmetinin kullanımıyla (müracaat, ameliyat sayıları vb.) ilgili veriler üzerinden sağlıkta özelleşme eğilimi incelenmiş olup seçilen bu göstergelere dayanarak mevcut/muhtemel riskler dile getirilmiş ve bazı somut politika önerileri takdim edilmiştir.
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Braga, Kesia, Andrej Slivnik, Flávia Carvalho, Maria Netto, Rafael Cavazzoni Lima, and Rodrigo Pereira Porto. Brasil: Fundos de aval como mecanismos de garantia para micro, pequenas e medias empresas. Banco Interamericano de Desenvolvimento, January 2023. http://dx.doi.org/10.18235/0004601.
Повний текст джерелаАнотація:
Este trabalho investiga a atuaço dos fundos de aval no Brasil para viabilizar o acesso ao crédito das micro, pequenas e médias empresas (MPMEs), com destaque para o uso das garantias como instrumento anticíclico em resposta aos efeitos da crise da Covid-19. A análise desenvolvida com base nos estatutos e regulamentos, dados de desempenho e de liçes aprendidas dos principais fundos garantidores nacionais, especialmente o Fundo Garantidor de Investimentos (FGI), administrado pelo Banco Nacional de Desenvolvimento Econmico e Social (BNDES), e o Fundo de Garantia de Operaçes (FGO), administrado pelo Banco do Brasil, o Fundo de Aval às Micro e Pequenas Empresas (FAMPE), gerido pelo Serviço Brasileiro de Apoio às Micro e Pequenas Empresas (Sebrae), e os programas garantidores criados na crise da Covid-19, o Programa Emergencial de Acesso a Crédito (FGI PEAC) e o Programa Nacional de Apoio às Microempresas e Empresas de Pequeno Porte (FGO Pronampe). O estudo argumenta que os fundos analisados viabilizaram o acesso ao financiamento por empresas que estariam impedidas pela falta de garantias. Além disso, identifica na saúde financeira dos próprios fundos o elemento fundamental para a sua eficácia, pois ela reflete a capacidade de honrar suas garantias e, consequentemente, afeta a confiança dos agentes financeiros e sua disposiço para fornecer crédito às empresas.