Добірка наукової літератури з теми "CRISPRko Screening"
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Статті в журналах з теми "CRISPRko Screening"
Evers, Bastiaan, Katarzyna Jastrzebski, Jeroen P. M. Heijmans, Wipawadee Grernrum, Roderick L. Beijersbergen, and Rene Bernards. "CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes." Nature Biotechnology 34, no. 6 (April 25, 2016): 631–33. http://dx.doi.org/10.1038/nbt.3536.
Повний текст джерелаWatters, Kyle E., Christof Fellmann, Hua B. Bai, Shawn M. Ren, and Jennifer A. Doudna. "Systematic discovery of natural CRISPR-Cas12a inhibitors." Science 362, no. 6411 (September 6, 2018): 236–39. http://dx.doi.org/10.1126/science.aau5138.
Повний текст джерелаSelle, Kurt, Todd R. Klaenhammer, and Rodolphe Barrangou. "CRISPR-based screening of genomic island excision events in bacteria." Proceedings of the National Academy of Sciences 112, no. 26 (June 15, 2015): 8076–81. http://dx.doi.org/10.1073/pnas.1508525112.
Повний текст джерелаKampmann, Martin, Max A. Horlbeck, Yuwen Chen, Jordan C. Tsai, Michael C. Bassik, Luke A. Gilbert, Jacqueline E. Villalta, et al. "Next-generation libraries for robust RNA interference-based genome-wide screens." Proceedings of the National Academy of Sciences 112, no. 26 (June 15, 2015): E3384—E3391. http://dx.doi.org/10.1073/pnas.1508821112.
Повний текст джерелаGöttl, Vanessa L., Ina Schmitt, Kristina Braun, Petra Peters-Wendisch, Volker F. Wendisch, and Nadja A. Henke. "CRISPRi-Library-Guided Target Identification for Engineering Carotenoid Production by Corynebacterium glutamicum." Microorganisms 9, no. 4 (March 24, 2021): 670. http://dx.doi.org/10.3390/microorganisms9040670.
Повний текст джерелаGÜLER KARA, Hale, Buket KOSOVA, Eda DOĞAN, Vildan BOZOK ÇETİNTAŞ, and Şerif ŞENTÜRK. "CRISPR-Cas Functional Genetic Screening: Traditional Review." Turkiye Klinikleri Journal of Medical Sciences 42, no. 4 (2022): 311–22. http://dx.doi.org/10.5336/medsci.2022-88507.
Повний текст джерелаLanning, Bryan R., and Christopher R. Vakoc. "Single-minded CRISPR screening." Nature Biotechnology 35, no. 4 (April 2017): 339–40. http://dx.doi.org/10.1038/nbt.3849.
Повний текст джерелаHaswell, Jeffrey R., Kaia Mattioli, Chiara Gerhardinger, Philipp G. Maass, Daniel J. Foster, Paola Peinado, Xiaofeng Wang, Pedro P. Medina, John L. Rinn, and Frank J. Slack. "Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency." PLOS ONE 16, no. 11 (November 3, 2021): e0252848. http://dx.doi.org/10.1371/journal.pone.0252848.
Повний текст джерелаAncos-Pintado, Raquel, Irene Bragado-García, María Luz Morales, Roberto García-Vicente, Andrés Arroyo-Barea, Alba Rodríguez-García, Joaquín Martínez-López, María Linares, and María Hernández-Sánchez. "High-Throughput CRISPR Screening in Hematological Neoplasms." Cancers 14, no. 15 (July 25, 2022): 3612. http://dx.doi.org/10.3390/cancers14153612.
Повний текст джерелаSerebrenik, Yevgeniy V., and Ophir Shalem. "CRISPR mutagenesis screening of mice." Nature Cell Biology 20, no. 11 (October 8, 2018): 1235–37. http://dx.doi.org/10.1038/s41556-018-0224-y.
Повний текст джерелаДисертації з теми "CRISPRko Screening"
Erard, Nicolas Pascal Jean. "Optimization of molecular tools for high-throughput genetic screening." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/271895.
Повний текст джерелаSheel, Ankur. "Identification of Essential Genes in Hepatocellular Carcinomas using CRISPR Screening." eScholarship@UMMS, 2019. https://escholarship.umassmed.edu/gsbs_diss/1039.
Повний текст джерелаRubanova, Natalia. "MasterPATH : network analysis of functional genomics screening data." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCC109/document.
Повний текст джерелаIn this work we developed a new exploratory network analysis method, that works on an integrated network (the network consists of protein-protein, transcriptional, miRNA-mRNA, metabolic interactions) and aims at uncovering potential members of molecular pathways important for a given phenotype using hit list dataset from “omics” experiments. The method extracts subnetwork built from the shortest paths of 4 different types (with only protein-protein interactions, with at least one transcription interaction, with at least one miRNA-mRNA interaction, with at least one metabolic interaction) between hit genes and so called “final implementers” – biological components that are involved in molecular events responsible for final phenotypical realization (if known) or between hit genes (if “final implementers” are not known). The method calculates centrality score for each node and each path in the subnetwork as a number of the shortest paths found in the previous step that pass through the node and the path. Then, the statistical significance of each centrality score is assessed by comparing it with centrality scores in subnetworks built from the shortest paths for randomly sampled hit lists. It is hypothesized that the nodes and the paths with statistically significant centrality score can be considered as putative members of molecular pathways leading to the studied phenotype. In case experimental scores and p-values are available for a large number of nodes in the network, the method can also calculate paths’ experiment-based scores (as an average of the experimental scores of the nodes in the path) and experiment-based p-values (by aggregating p-values of the nodes in the path using Fisher’s combined probability test and permutation approach). The method is illustrated by analyzing the results of miRNA loss-of-function screening and transcriptomic profiling of terminal muscle differentiation and of ‘druggable’ loss-of-function screening of the DNA repair process. The Java source code is available on GitHub page https://github.com/daggoo/masterPATH
Li, Meng. "Genetic dissection of the exit of pluripotency in mouse embryonic stem cells by CRISPR-based screening." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/277552.
Повний текст джерелаKaemena, Daniel Fraser. "CRISPR/Cas9 genome-wide loss of function screening identifies novel regulators of reprogramming to pluripotency." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31184.
Повний текст джерелаPetrucci, Teresa. "Building a platform for flexible and scalable testing of genetic editors." Doctoral thesis, Università di Siena, 2021. http://hdl.handle.net/11365/1143160.
Повний текст джерелаSczakiel, Henrike Lisa [Verfasser]. "Identifizierung Pathogenese-relevanter Kandidatengene im Hodgkin-Lymphom durch CRISPR/Cas9-basiertes knockout-Screening / Henrike Lisa Sczakiel." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2021. http://d-nb.info/1228859523/34.
Повний текст джерелаLam, Phuong T. "Crispr/cas9-mediated genome editing of human pluripotent stem cells to advance human retina regeneration research." Miami University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=miami1575372014701457.
Повний текст джерелаCresson, Marie. "Study of chikungunya virus entry and host response to infection." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE1050.
Повний текст джерелаAlphaviruses are a group of enveloped, positive-sense RNA viruses which are distributed almost worldwide and are responsible for a considerable number of human and animal diseases. Among these viruses, the Chikungunya virus (CHIKV) has recently re-emerged and caused several outbreaks on all continents in the past decade. Despite many studies, molecular mechanisms of chikungunya virus replication and virus-host interactions remain poorly understood. The aim of my project was to better understand and characterize the CHIKV entry and the host factors involved during replication steps in mammals. Several different approaches have been used in this work. As a first step, we have demonstrated a decrease of CHIKV infection after iron treatment in form of ferric ammonium citrate and we have studied the potential role in viral entry of NRAMP2 and TFRC, two proteins involved in iron transport and known receptors for other viruses. On the other hand, we have also focused on two proteins, CD46 and TM9SF2, identified through an RNAi screen in collaboration, in order to determine if they are required as entry factors for chikungunya virus. In a last axis, we have set up and carried out a genome-wide loss of function screen with the CRISPR/Cas9 technology in order to identify host factors important for chikungunya virus entry, replication or virus-induced cell death. Although it appears that screen conditions should be optimized, we have identified potential candidates required for CHIKV infection and we are currently testing them
Mohammad, Jiyan Mageed. "Therapeutic Potential of Piperlongumine for Pancreatic Ductal Adenocarcinoma." Diss., North Dakota State University, 2019. https://hdl.handle.net/10365/31347.
Повний текст джерелаNIH
Книги з теми "CRISPRko Screening"
Barilan, Y. Michael, Margherita Brusa, and Aaron Ciechanover, eds. Can precision medicine be personal; Can personalized medicine be precise? Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780198863465.001.0001.
Повний текст джерелаЧастини книг з теми "CRISPRko Screening"
Henriksson, Johan. "CRISPR Screening in Single Cells." In Methods in Molecular Biology, 395–406. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9240-9_23.
Повний текст джерелаNishiga, Masataka, Lei S. Qi, and Joseph C. Wu. "CRISPRi/a Screening with Human iPSCs." In Methods in Molecular Biology, 261–81. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1484-6_23.
Повний текст джерелаPort, Fillip, and Michael Boutros. "Tissue-Specific CRISPR-Cas9 Screening in Drosophila." In Methods in Molecular Biology, 157–76. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2541-5_7.
Повний текст джерелаDeLuca, Sophia, and Nenad Bursac. "CRISPR Library Screening in Cultured Cardiomyocytes." In Methods in Molecular Biology, 1–13. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2261-2_1.
Повний текст джерелаCarstens, Carsten P., Katherine A. Felts, and Sarah E. Johns. "Construction of CRISPR Libraries for Functional Screening." In Synthetic Biology, 139–50. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7795-6_7.
Повний текст джерелаWebster, Daniel E., Sandrine Roulland, and James D. Phelan. "Protocols for CRISPR-Cas9 Screening in Lymphoma Cell Lines." In Methods in Molecular Biology, 337–50. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9151-8_16.
Повний текст джерелаHaney, Steven A. "High-Content Screening Approaches That Minimize Confounding Factors in RNAi, CRISPR, and Small Molecule Screening." In Methods in Molecular Biology, 113–30. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7357-6_8.
Повний текст джерелаKlann, Tyler S., Gregory E. Crawford, Timothy E. Reddy, and Charles A. Gersbach. "Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing." In Methods in Molecular Biology, 447–80. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7774-1_25.
Повний текст джерелаCarlini, Valentina, Kristjan H. Gretarsson, and Jamie A. Hackett. "Genome-Scale CRISPR Screening for Regulators of Cell Fate Transitions." In Methods in Molecular Biology, 91–108. New York, NY: Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0958-3_7.
Повний текст джерелаShang, Wanjing, Fei Wang, Qi Zhu, Liangyu Wang, and Haopeng Wang. "CRISPR/Cas9-Based Genetic Screening to Study T-Cell Function." In Methods in Molecular Biology, 59–70. New York, NY: Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0266-9_5.
Повний текст джерелаТези доповідей конференцій з теми "CRISPRko Screening"
le Sage, Carlos, Prince Panckier, and Bendict CS Cross. "Abstract A186: Dual CRISPRi and CRISPRa screening reveals phenotypic switches in response to BRAF inhibition." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; October 26-30, 2017; Philadelphia, PA. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1535-7163.targ-17-a186.
Повний текст джерелаCross, Benedict CS, Steffen Lawo, Tim ME Scales, Caroline Archer, Jessica Hunt, Alessandro Riccombeni, Leigh Brody, et al. "Abstract B163: Genetic screening with CRISPR-Cas9: Proof and principles." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; November 5-9, 2015; Boston, MA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1535-7163.targ-15-b163.
Повний текст джерелаTedesco, Donato, Paul Diehl, Mikhail Makhanov, Sylvain Baron, Dmitry Suchkov, and Alex Chenchik. "Abstract C161: CRISPR/Cas9 genome-wide gRNA library screening platform." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; November 5-9, 2015; Boston, MA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1535-7163.targ-15-c161.
Повний текст джерелаTan, Jenille M., and Scott E. Martin. "Abstract 73: Exploring arrayed synthetic CRISPR for functional genomic screening." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-73.
Повний текст джерелаLi, Wanji. "Development and Application of CRISPR-Mediated Genetic Screening in Oncology." In ICBBE '20: 2020 7th International Conference on Biomedical and Bioinformatics Engineering. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3444884.3444909.
Повний текст джерелаWei, Yiliang, and Christopher Vakoc. "Abstract 5161: Probing leukemia vulnerabilitiesin vivousing domain-focused CRISPR screening." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-5161.
Повний текст джерелаWei, Yiliang, and Christopher Vakoc. "Abstract 5161: Probing leukemia vulnerabilitiesin vivousing domain-focused CRISPR screening." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-5161.
Повний текст джерелаGrassian, Alexandra R., Julian Fowler, Igor Feldman, Thomas Riera, Darren Harvey, Allison E. Drew, Richard Chesworth, et al. "Abstract B78: CRISPR pooled screening identifies differential dependencies on epigenetic pathways." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; November 5-9, 2015; Boston, MA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1535-7163.targ-15-b78.
Повний текст джерелаVakoc, Christopher. "Abstract IA07: Cancer drug target identification using domain-focused CRISPR screening." In Abstracts: Advances in Sarcomas: From Basic Science to Clinical Translation; May 16-19, 2017; Philadelphia, PA. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1557-3265.sarcomas17-ia07.
Повний текст джерелаBehan, F., F. Iorio, E. Stronach, C. Beaver, R. Moita Santos, J. Saez-Rodriguez, K. Yusa, and M. Garnett. "SPOT-012 Large-scale CRISPR screening to identify actionable cancer drug targets." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.45.
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