Статті в журналах з теми "Crampon"

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1

Luo, Zhong Hua. "Optimization Design for Luffing Mechanism of Portal Slewing Crane." Applied Mechanics and Materials 577 (July 2014): 305–9. http://dx.doi.org/10.4028/www.scientific.net/amm.577.305.

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This paper conducts a comprehensive study on the optimization design for luffing mechanism of portal slewing crane. First, displacement formulae are derived of crampon hinge point of the luffing mechanism. Secondly, mathematical model is established for luffing mechanism optimization design of portal slewing crane, according to the mechanism characteristics, and, with an aim of making crampon hinge end point to move horizontally, and of satisfying the value of maximum and minimum amplitude, and of saving material, etc. Finally, program of optimization design is compiled for the luffing mechanism of portal slewing crane. The luffing mechanism of M4022 portal slewing crane is optimized, and the optimization result is satisfactory. This paper makes it possible to obtain not only each rod length and cross-section area, but also obtain the counterbalance weight and the each rod maximum force of the luffing mechanism.
2

Hawkins, J. David. "The Usage of the Hieroglyphic Luwian Sign “Crampon” (L.386)." Kadmos 49, no. 1 (January 2011): 1–10. http://dx.doi.org/10.1515/kadmos.2010.001.

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3

Maughan, Ronald J., and Susan M. Shirreffs. "Muscle Cramping During Exercise: Causes, Solutions, and Questions Remaining." Sports Medicine 49, S2 (November 6, 2019): 115–24. http://dx.doi.org/10.1007/s40279-019-01162-1.

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Abstract Muscle cramp is a temporary but intense and painful involuntary contraction of skeletal muscle that can occur in many different situations. The causes of, and cures for, the cramps that occur during or soon after exercise remain uncertain, although there is evidence that some cases may be associated with disturbances of water and salt balance, while others appear to involve sustained abnormal spinal reflex activity secondary to fatigue of the affected muscles. Evidence in favour of a role for dyshydration comes largely from medical records obtained in large industrial settings, although it is supported by one large-scale intervention trial and by field trials involving small numbers of athletes. Cramp is notoriously unpredictable, making laboratory studies difficult, but experimental models involving electrical stimulation or intense voluntary contractions of small muscles held in a shortened position can induce cramp in many, although not all, individuals. These studies show that dehydration has no effect on the stimulation frequency required to initiate cramping and confirm a role for spinal pathways, but their relevance to the spontaneous cramps that occur during exercise is questionable. There is a long history of folk remedies for treatment or prevention of cramps; some may reduce the likelihood of some forms of cramping and reduce its intensity and duration, but none are consistently effective. It seems likely that there are different types of cramp that are initiated by different mechanisms; if this is the case, the search for a single strategy for prevention or treatment is unlikely to succeed.
4

Khan, Serajul I., and John A. Burne. "Reflex Inhibition of Normal Cramp Following Electrical Stimulation of the Muscle Tendon." Journal of Neurophysiology 98, no. 3 (September 2007): 1102–7. http://dx.doi.org/10.1152/jn.00371.2007.

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Muscle cramp was induced in one head of the gastrocnemius muscle (GA) in eight of thirteen subjects using maximum voluntary contraction when the muscle was in the shortened position. Cramp in GA was painful, involuntary, and localized. Induction of cramp was indicated by the presence of electromyographic (EMG) activity in one head of GA while the other head remained silent. In all cramping subjects, reflex inhibition of cramp electrical activity was observed following Achilles tendon electrical stimulation and they all reported subjective relief of cramp. Thus muscle cramp can be inhibited by stimulation of tendon afferents in the cramped muscle. When the inhibition of cramp-generated EMG and voluntary EMG was compared at similar mean EMG levels, the area and timing of the two phases of inhibition (I1, I2) did not differ significantly. This strongly suggests that the same reflex pathway was the source of the inhibition in both cases. Thus the cramp-generated EMG is also likely to be driven by spinal synaptic input to the motorneurons. We have found that the muscle conditions that appear necessary to facilitate cramp, a near to maximal contraction of the shortened muscle, are also the conditions that render the inhibition generated by tendon afferents ineffective. When the strength of tendon inhibition in cramping subjects was compared with that in subjects that failed to cramp, it was found to be significantly weaker under the same experimental conditions. It is likely that reduced inhibitory feedback from tendon afferents has an important role in generating cramp.
5

Miller, Kevin C., and Kenneth L. Knight. "Initial Electrical Stimulation Frequency and Cramp Threshold Frequency and Force." Journal of Athletic Training 47, no. 6 (November 1, 2012): 643–47. http://dx.doi.org/10.4085/1062-6050-47.5.12.

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Context In the electrically induced cramp model, the tibial nerve is stimulated at an initial frequency of 4 Hz with increases in 2-Hz increments until the flexor hallucis brevis cramps. The frequency at which cramping occurs (ie, threshold frequency [TF]) can vary considerably. A potential limitation is that multiple subthreshold stimulations before TF might induce fatigue, which is operationally defined as a decrease in maximal voluntary isometric contraction (MVIC) force, thereby biasing TF. Objective To determine if TF is similar when initially stimulated at 4 Hz or 14 Hz and if MVIC force is different among stimulation frequencies or over time (precramp, 1 minute postcramp, and 5 minutes postcramp). Design Crossover study. Setting Laboratory. Patients or Other Participants Twenty participants (13 males: age = 20.6 ± 2.9 years, height = 184.4 ± 5.7 cm, mass = 76.3 ± 7.1 kg; 7 females: age = 20.4 ± 3.5 years, height = 166.6 ± 6.0 cm, mass = 62.4 ± 10.0 kg) who were prone to cramps. Intervention(s) Participants performed 20 practice MVICs. After a 5-minute rest, three 2-second MVICs were recorded and averaged for the precramp measurement. Participants were stimulated at either 4 Hz or 14 Hz, and the frequency was increased in 2-Hz increments from each initial frequency until cramp. The MVIC force was reevaluated at 1 minute and 5 minutes postcramp. Main Outcome Measure(s) The TF and MVIC force. Results Initial stimulation frequency did not affect TF (4 Hz = 16.2 ± 3.8 Hz, 14 Hz = 17.1 ± 5.0 Hz; t19=1.2, P = .24). Two participants had inaccurate TFs when initially stimulated at 14 Hz; they cramped at 10 and 12 Hz in the 4-Hz condition. The MVIC force did not differ between initial frequencies (F1,19 = 0.9, P = .36) but did differ over time (F2,38 = 5.1, P = .01). Force was lower at 1 minute postcramp (25.1 ± 10.1 N) than at precramp (28.7 ± 7.8 N; P < .05) but returned to baseline at 5 minutes postcramp (26.7 ± 8.9 N; P > .05). Conclusions The preferred initial stimulation frequency might be 4 Hz because it did not alter or overestimate TF. The MVIC force was lower at 1 minute postcramp, suggesting the induced cramp rather than the varying electrical frequencies affected force. A 1- to 5-minute rest should be provided postcramp induction if multiple cramps are induced.
6

Bhuvaneswari, P. G., S. Tamilselvi, J. Harini, J. Harshini, and R. Parameshwari. "A study to assess the effectiveness of Intradialytic Stretching Exercises on Leg Muscle Cramp among Hemo Dialysis." CARDIOMETRY, no. 23 (August 20, 2022): 97–102. http://dx.doi.org/10.18137/cardiometry.2022.23.97102.

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INTRODUCTION: Hemodialysis is a continuous treatment that might result in problems such as hypotension, leg muscle cramps, disequilibrium syndrome, and nausea. The most effective treatment is passive stretching of the shortened muscle. Stretching has numerous health benefits, including increasing stamina, relaxing the body and mind, improving focus and concentration, and lowering the chance of injury. OBJECTIVE: The goals of this study were to determine the severity of leg muscle cramps in Hemodialysis patients before and after intradialytic stretching exercises, to assess the effectiveness of intradialytic stretching exercises on leg muscle cramps in Hemodialysis patients, and to link the severity of leg muscle cramps with selected demographic variables following intradialytic stretching exercises. MATERIALS AND METHODS: Qualitative research approach was conducted at Saveetha Medical College and Hospital by using quasi experimental research design, the Sample size was 30 patients with leg muscle cramps undergoing Hemodialysis by using Purposive sampling technique. The muscle cramp questionnaire scale was created to determine the severity of leg muscle cramps before and after Hemodialysis. Pain Scores ranged from 0 to 10 on a numerical scale. Before the individuals were given the intradialytic stretching exercise, demographic data, clinical variables and muscle cramp status were measured as a pre-test. Then, every day after the intervention, the posttest muscle cramp was measured. RESULTS: The demographic and clinical variables data was analysed using descriptive and inferential statistics. The majority of the patients 17(56.7%) reported no pain during the post-test. There was no correlation between the severity of leg muscle cramping and any of the demographic variables. Data were categorized and analysed using descriptive (mean, percentage, and standard deviation) and inferential statistics (independent paired t test’, chi-square analysis). CONCLUSION: This study showed that regular stretching exercises on legs during the hemodialysis can help alleviate the leg muscle cramps.
7

Srinubabu, K., L. Parimala, and P. Thenmozhi. "Effectiveness of Isotonic Exercise in Reduction of Muscle Cramps among Hemodialysis Patients in Dialysis Unit." CARDIOMETRY, no. 23 (August 20, 2022): 117–22. http://dx.doi.org/10.18137/cardiometry.2022.23.117122.

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Background: Kidney is a vital organ and the main function is to remove waste products and excess water from the blood. Different kidney pathogenesis challenges the function of human body and puts human life danger. Two such important pathogenesis is acute and chronic renal failure. The incidence of acute renal failure has been estimated to be 209 patients per million populations per year and 37% of patients treated in intensive care units. Muscle cramps also can occur when patients are below dry weight. The severe muscle cramping experienced near the end of the hemodialysis treatment and persisting for a time after hemodialysis often is due to dehydration. Treatment for cramping varies from unit to unit. When patients are having cramping and have low blood pressure, the staff may give normal saline. Aim of the study: The main aim of the study to assess effectiveness of isotonic exercise on muscle cramps among hemodialysis patients. Methods: Quantitative research design was adopted for the study with 60 samples which met the inclusion criteria were selected by convenience sampling technique. Demographic variables data were collected by using a multiple-choice questionnaire followed by Pretest was conducted by using muscle cramp assessment tool for both experimental group and control group. Isotonic exercise was given 10 to 15 minutes at one session for experimental group Post test was conducted by using muscle cramps assessment tool and for both experimental group and control group. Result: Out of 60 samples, The calculated student Independent ‘t’ test value of t = 2.500 was found to be statistically highly significant at p<0.05 level. This clearly infers that isotonic exercise on muscle cramps administered to hemodialysis patients in the experimental group was found to be effective in reducing the level of muscle cramps in the post test than the hemodialysis patients in the control group. Conclusion: There was a significant improvement in reduction of muscle cramps those who received isotonic exercise intervention than those who do not receive the isotonic exercise.
8

Stofan, John R., Jeffrey J. Zachwieja, Craig A. Horswill, Robert Murray, Scott A. Anderson, and E. Randy Eichner. "Sweat and Sodium Losses in NCAA Football Players: A Precursor to Heat Cramps?" International Journal of Sport Nutrition and Exercise Metabolism 15, no. 6 (December 2005): 641–52. http://dx.doi.org/10.1123/ijsnem.15.6.641.

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This observational study was designed to determine whether football players with a history of heat cramps have elevated fluid and sodium losses during training. During a “two-a-day” training camp, five Division I collegiate football players (20.2 ± 1.6 y, 113 ± 20 kg) with history of heat cramps (C) were matched (weight, age, race and position) with a cohort of teammates (19.6 ± 0.6 y, 110 ± 20 kg) who had never cramped (NC). Change in body weight (adjusted by fluid intake) determined gross sweat loss. Sweat samples (forearm patch) were analyzed for sodium and potassium concentrations. Adlibitum fluid intake was measured by recording pre- and post-practice bottle weights. Average sweat sodium loss for a 2.5-h practice was projected at 5.1 ± 2.3 g (C) vs. 2.2 ± 1.7 g (NC). When averaged across two practices within the day, fluid intake was similar between groups (C: 2.6 ± 0.8 L vs. NC: 2.8 ± 0.7 L), as was gross sweat loss (C: 4.0 ± 1.1 L vs. NC: 3.5 ± 1.6 L). There was wide variability in the fluid deficit incurred for both C and NC (1.3 ± 0.9 vs. 0.7 ± 1.2%) due to fluid intake. Sweat potassium was similar between groups, but sweat sodium was two times higher in C versus NC (54.6 ± 16.2 vs. 25.3 ± 10.0 mmol/L). These data indicate that sweat sodium losses were comparatively larger in cramp-prone football players than in NC. Although both groups consumed sodium-containing fluids (on-field) and food (off-field), both appeared to experience an acute sodium deficit at the end of practices based on sweat sodium losses. Large acute sodium and fluid losses (in sweat) may be characteristic of football players with a history of heat cramping.
9

Zichella, Lorena, Fiorenza Baudana, Giovanna Zanetti, and Paola Marini. "Vinyl-Asbestos Floor Risk Exposure in Three Different Simulations." International Journal of Environmental Research and Public Health 18, no. 4 (February 20, 2021): 2073. http://dx.doi.org/10.3390/ijerph18042073.

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Vinyl floors are widely used in public areas for their low cost and easy cleaning. From 1960 to 1980, asbestos was often added to improve vinyl floor performances. The Italian Ministerial Decree (M.D.) 06/09/94 indicates asbestos vinyl tiles as non-friable materials and, therefore, few dangerous to human health. This work aims to check through three different experimental tests if asbestos floor tiles, after decades of use, maintain their characteristics of compactness and non-friability. The effect of a small stone fragment stuck in the sole of rubber shoes was reproduced by striking the vinyl floor with a crampon. A vinyl tile was broken into smaller pieces with the aid of pliers to simulate what normally happens when workers replace the floors or sample it to verify the presence of asbestos. The third test reproduced the abrasion of the tile surface due to the dragging of furniture or heavy materials or sand grains that remain attached to the soles of shoes. The tests were carried out in safe conditions, working under an extractor hood with a glove box. Airborne sampling in the hood obtained the concentration of asbestos fibers produced in each test. The simulation tests performed confirms the possible release of fibers if the vinyl tiles are cut, abraded or perforated, as indicated by the Italian M.D.
10

Katzberg, Hans D., Vera Bril, Sarah Riaz, and Carolina Barnett. "Qualitative, Patient-Centered Assessment of Muscle Cramp Impact and Severity." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 46, no. 6 (August 27, 2019): 735–41. http://dx.doi.org/10.1017/cjn.2019.286.

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ABSTRACT:Background:There is an urgent need for new therapeutic options to treat muscle cramps; however, no patient-reported measures exist that capture the entire cramp experience. We conducted a qualitative study to assess the experience of patients suffering muscle cramps, aiming to understand what factors determine the impact cramps have in patients’ lives to guide the development of a patient-centered outcome measure of cramp severity and impact.Methods:We enrolled patients with cramps due to several etiologies, including motor neuron disease, pregnancy-induced cramps, cirrhosis and hemodialysis, and idiopathic and exercise-induced cramps. Patients participated in semistructured interviews about their experiences with muscle cramps and their responses were recorded and transcribed. Data were analyzed with content analysis using data saturation to determine the sample size. We subsequently developed a conceptual framework of cramp severity and overall cramp impact.Results:Ten patients were interviewed when data saturation was reached. The cramp experience was similar across disease and physiological states known to cause muscle cramps. The main themes that compose the overall cramp impact are cramp characteristics, sleep interference, daytime activities interference, and the effect on mental health.Conclusions:This framework will be used to develop a patient-reported outcome of cramp severity and impact.
11

Saito, Miyoko, Natasha J. Olby, Leticia Obledo, and Jody L. Gookin. "Muscle Cramps in Two Standard Poodles With Hypoadrenocorticism." Journal of the American Animal Hospital Association 38, no. 5 (September 1, 2002): 437–43. http://dx.doi.org/10.5326/0380437.

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Two standard poodles were evaluated for painful, episodic muscle cramps affecting their thoracic and pelvic limbs. Both dogs had been diagnosed with hypoadrenocorticism and were being treated with fludrocortisone acetate and prednisone when evaluated for muscle cramps. However, the muscle cramping started approximately 1 month prior to the diagnosis of hypoadrenocorticism. Findings on general physical examination included lethargy and dehydration. Neurological examination was normal between episodes. Serum biochemical abnormalities included hyperalbuminemia, azotemia, hyponatremia, hypochloremia, and hyperkalemia. Altering treatment to desoxycorticosterone pivalate resolved the electrolyte abnormalities and the episodes of muscle cramping in both dogs. The authors conclude that hypoadrenocorticism can be associated with episodes of painful muscle cramping in standard poodles.
12

Watanabe, Tomonobu M., Hiroshi Tokuo, Kosuke Gonda, Hideo Higuchi та Mitsuo Ikebe. "1P-141 Interaction between myosin-X and integrin-β acts as a crampon during filopodia protrusion(The 46th Annual Meeting of the Biophysical Society of Japan)". Seibutsu Butsuri 48, supplement (2008): S43. http://dx.doi.org/10.2142/biophys.48.s43_2.

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13

Achwan, Achwan, and Abdurahman B. B. Laksono. "Breathing And Stretching Exercises Affect The Decrease in The Intensity of Leg Cramp Pain." Jurnal Ilmu dan Teknologi Kesehatan 8, no. 2 (March 31, 2021): 182–92. http://dx.doi.org/10.32668/jitek.v8i2.539.

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Leg cramps are a common side effect of intradialysis CKD patients. Preventing intradialysis cramping pain can improve quality of life. Breathing and stretching exercises are non-pharmacological treatments for cramping pain. The purpose of this study was to prove the effect of breathing and stretching exercises on changes in the intensity of leg cramps in hemodialysis patients at the Haji Jakarta Hospital in 2018. This study was a quasi-experimental study with a two-group pre-post test research design. The sample was selected by purposive sampling, a sample of 34 patients. The intensity of muscle cramps was measured using the Numeric Rating Scale. The results of the analysis using the paired sample T-test. The results showed that the intervention group had a P-value = 0.01 and the control group had a P-value = 0.055, meaning that there was a difference in mean the intensity of cramping pain before and after breathing and stretching exercises was compared, so it was concluded that there was an effect of breathing and stretching exercises on the intensity of intradialysis leg cramps. Patients are advised to breathing and stretching exercises regularly, light exercise, eat and drink diet.
14

P, Sinthia, M. Malathi, S. Nagarajan, Anitha Juiette, and Nalini M. "Early Detection of Exercise - Associated Muscle cramp." YMER Digital 21, no. 01 (January 17, 2022): 251–60. http://dx.doi.org/10.37896/ymer21.01/23.

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One of the deep and painful involuntary contractions of skeletal muscle is muscle cramp which takes place during various other conditions. The origin for the cramps that occur during or soon after exercise and the appropriate remedies continue to prove uncertain. Soon after an implant process and forceful workout, past voluntary dehydration cramps occur at many sections. The process of identifying the type of cramp is time consuming and treatment process to cramps is also quite tedious. If not treated at the right time, Muscle cramps may cause vigorous side effects and worsening in day to day physiological activities. The main motive of this vest is to locate and identify the cramp and alert so that further injury can be detected. It would also be helpful in preventing the person from further muscular cramps and other complications. EMG signals which are obtained from adhesive electrodes are amplified by using IC741 (op-amp) with instrumentation amplifier configuration.LM35 temperature sensor is used to monitor the temperature at specified locations. Wherever the cramp occurring possibilities are high. Flex sensor is used to identify the abnormal contraction and relaxation muscles in upper limbs. The three input bio potential signals are fed to the micro controller (Arduino UNO). The main objective of this system is to provide a comfortable vest which would monitor the cramps occurring in athletes whenever it occurs. Therefore with the help of this wearable device muscle cramps occurring at upper limbs can be detected and further injuries, complications such as fractures can be reduced.
15

Goodman, Ashley, and Kevin A. Zwetsloot. "Voluntary Inducement of Triceps Surae Muscle Cramping." International Journal of Athletic Therapy and Training 18, no. 6 (November 2013): 40–43. http://dx.doi.org/10.1123/ijatt.18.6.40.

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Context:Exercise-associated muscle cramping (EAMC) is difficult to induce experimentally.Purpose:T o assess the reliability of a maximum voluntary contraction (MVC) procedure for inducement of a muscle cramp.Participants:Seventy-four healthy and physically active participants (23 ± 8 years of age; 49 males and 25 females); 63 who had previously experienced EAMC.Main Outcome Measure:Each participant’s triceps surae musculature was placed in a shortened and unloaded position. Participants were instructed to maximally contract the triceps surae musculature with the intent to induce a cramp within 60 seconds.Results:Cramping was induced in 31% of participants within 60 seconds, and 97% of participants who experienced cramping during the initial session and who returned for two subsequent testing sessions at one-week intervals reproduced cramping with the procedure.Conclusions:The MVC procedure consistently induced cramping in a subset of 18 cramp-prone participants during multiple testing sessions, which suggests that it may have value as a screening tool for identification of athletes with a predisposition for EAMC.
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Ghimire, Madhav, Sanjib Kumar Sharma, Romila Chimoriya, and Gopal Chandra Das. "Intradialytic Muscle Cramp and its Association with Peripheral Arterial Disease in End Stage Renal Disease Patients on Hemodialysis." Journal of Nepal Medical Association 52, no. 196 (December 31, 2014): 967–71. http://dx.doi.org/10.31729/jnma.2795.

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Introduction: Muscle cramp is a common intradialytic complication observed in hemodialysis patients. Similarly Peripheral arterial disease is a common condition in the hemodialysis population. No study on intradialytic muscle cramp and its association with Peripheral arterial disease is yet reported from Nepal. Methods: Fifty patients with a diagnosis of End Stage Renal Disease who were on hemodialysis were studied over a period of one year. Muscle cramp was defined clinically as contractions of a large muscle group and Peripheral arterial disease was diagnosed on the basis of the ankle –brachial index. Chi square (X2) test was used to determine the association between Intradialytic Muscle cramps and Peripheral Arterial Disease. Results: A total of 50 End Stage Renal Disease patients were analyzed. The mean age of the patient was 49.81±12.63 years. The major causes of End Stage Renal Disease in the study population was Chronic Glomerulonephritis 40 % (n=20). Muscle cramps were present in 26% (n=13) cases. Peripheral arterial disease was present in 30% (n=15) of patients. However there was no statistically significant association between the presence of Intradialytic Muscle cramps and peripheral arterial disease (p value =0.18) Conclusions: Intradialytic Muscle cramps and peripheral arterial disease were common occurrence in end stage renal disease patients on hemodialysis patients, however there was no association between the presence of intradialytic Muscle cramps and peripheral arterial disease. Keywords: end stage renal disease; intradialytic muscle cramps; peripheral arterial disease.
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Hinoshita, Fumihiko, Yosuke Ogura, Yoshio Suzuki, Shigeko Hara, Akira Yamada, Naoko Tanaka, Akira Yamashita, and Fumiaki Marumo. "Effect of Orally Administered Shao-Yao-Gan-Cao-Tang (Shakuyaku-kanzo-to) on Muscle Cramps in Maintenance Hemodialysis Patients: A Preliminary Study." American Journal of Chinese Medicine 31, no. 03 (January 2003): 445–53. http://dx.doi.org/10.1142/s0192415x03001144.

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Muscle cramps are one of the most common complications of hemodialysis (HD), and often are a source of great pain in spite of various clinical measures. The traditional herbal medicine, Shao-Yao-Gan-Cao-Tang (Japanese name: Shakuyaku-kanzo-to), consists of equal amounts of paeony and licorice roots, and has been used in Japan and China for muscle pain or skeletal muscle tremors. To determine whether this medicine is able to prevent frequent and unendurable muscle cramps in patients undergoing HD, Shakuyaku-kanzo-to at 6 g per day was prospectively administered for 4 weeks to five patients on HD who were suffering from frequent muscle cramps. The frequency and severity of cramping before and after the treatment were carefully observed and compared. Skeletal muscle cramps completely disappeared in two of the treated patients after the start of oral administration of Shakuyaku-kanzo-to. Moreover, the frequency of cramping was significantly decreased in two of the remaining three patients after persistent administration. The severity of muscle cramps was also decreased by this treatment in the responsive patients. No serious side effects were detected during the treatment period. The inhibitory effect of Shakuyaku-kanzo-to on muscle contraction was also experimentally examined by using phrenic nerve-diaphragm preparations from male Wistar rats. Differences between the twitch responses were determined when the diaphragms and the nerves were stimulated in the presence and absence of the extract of Shakuyaku-kanzo-to. The results demonstrated that extracts of paeony and licorice roots inhibit contraction of skeletal muscles in rats. Taken together, we suggest that administration of Shakuyaku-kanzo-to is a safe, effective treatment for preventing muscle cramps in patients undergoing HD.
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Miller, Kevin C., Kenneth L. Knight, Steven R. Wilding, and Marcus B. Stone. "Duration of Electrically Induced Muscle Cramp Increased by Increasing Stimulation Frequency." Journal of Sport Rehabilitation 21, no. 2 (May 2012): 182–85. http://dx.doi.org/10.1123/jsr.21.2.182.

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Context:Electrically induced muscle cramps (EIMC) do not last long enough to study many cramp treatments. Increasing stimulation frequency lengthens cramp duration; it is unknown which frequency elicits the longest EIMC.Objective:To determine which stimulation frequency elicits the longest EIMC and whether cramp duration and stimulation frequency are correlated.Design:Randomized, crossover.Setting:Laboratory.Participants:20 participants (12 male, 8 female; age 20.7 ± 0.6 y; height 174.9 ± 1.9 cm; mass 76.6 ± 2.2 kg) with a self-reported history of muscle cramps in their lower extremities within the 6 mo before the study.Interventions:The dominant leg’s tibial nerve was percutaneously stimulated with 2-s-duration electrical stimuli trains starting at a frequency of 4 Hz. After 1 min of rest, stimulation frequency increased in 2-Hz increments until a cramp occurred in the flexor hallucis brevis. The stimulation frequency at which a cramp occurred was termed cramp threshold frequency (TF). Cramp duration was determined using strict clinical criteria (loss of hallux rigidity and return of hallux neutral). On the next 4 consecutive days, participants were stimulated at 5, 10, 15, or 20 Hz above TF, and cramp duration was reassessed.Main Outcome Measures:Cramp TF and duration.Results:Cramp TF was 16.9 ± 5.1 Hz. Cramp duration was longer at 15 and 20 Hz above TF (77.9 ± 37.6 s and 69.5 ± 36.9 s, respectively) than at TF (40.8 ± 34.0 s; P < .05). Cramp duration and TF were highly correlated (r = .90). Conclusions: Stimulating at 15 and 20 Hz above cramp TF produces the longest-lasting EIMC.
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Varghese, Akshay, Eduardo Lacson, Jessica M. Sontrop, Rey R. Acedillo, Ahmed A. Al-Jaishi, Sierra Anderson, Amit Bagga, et al. "A Higher Concentration of Dialysate Magnesium to Reduce the Frequency of Muscle Cramps: A Narrative Review." Canadian Journal of Kidney Health and Disease 7 (January 2020): 205435812096407. http://dx.doi.org/10.1177/2054358120964078.

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Purpose of review: Strategies to mitigate muscle cramps are a top research priority for patients receiving hemodialysis. As hypomagnesemia is a possible risk factor for cramping, we reviewed the literature to better understand the physiology of cramping as well as the epidemiology of hypomagnesemia and muscle cramps. We also sought to review the evidence from interventional studies on the effect of oral and dialysate magnesium-based therapies on muscle cramps. Sources of information: Peer-reviewed articles. Methods: We searched for relevant articles in major bibliographic databases including MEDLINE and EMBASE. The methodological quality of interventional studies was assessed using a modified version of the Downs and Blacks criteria checklist. Key findings: The etiology of muscle cramps in patients receiving hemodialysis is poorly understood and there are no clear evidence-based prevention or treatment strategies. Several factors may play a role including a low concentration of serum magnesium. The prevalence of hypomagnesemia (concentration of <0.7 mmol/L) in patients receiving hemodialysis ranges from 10% to 20%. Causes of hypomagnesemia include a low dietary intake of magnesium, use of medications that inhibit magnesium absorption (eg, proton pump inhibitors), increased magnesium excretion (eg, high-dose loop diuretics), and a low concentration of dialysate magnesium. Dialysate magnesium concentrations of ≤0.5 mmol/L may be associated with a decrease in serum magnesium concentration over time. Preliminary evidence from observational and interventional studies suggests a higher dialysate magnesium concentration will raise serum magnesium concentrations and may reduce the frequency and severity of muscle cramps. However, the quality of evidence supporting this benefit is limited, and larger, multicenter clinical trials are needed to further determine if magnesium-based therapy can reduce muscle cramps in patients receiving hemodialysis. In studies conducted to date, increasing the concentration of dialysate magnesium appears to be well-tolerated and is associated with a low risk of symptomatic hypermagnesemia. Limitations: Few interventional studies have examined the effect of magnesium-based therapy on muscle cramps in patients receiving hemodialysis and most were nonrandomized, pre-post study designs.
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Kumari, M. J., Kiruthika SR Kiruthika SR, Sreejith Parameswaran, and Arul Nisha. "Effect of Intradialytic Stretching Exercises on Lower Limbs Muscle Cramps among Patients Undergoing Regular Haemodialysis." Nursing Journal of India CXV, no. 02 (2024): 70–76. http://dx.doi.org/10.48029/nji.2024.cxv204.

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Many patients suffer with muscle cramps and discomfort during the haemodialysis procedure. Intradialytic stretching exercises are helpful in reducing the intensity of muscle cramps. The study objective was to evaluate the effect of intradialytic stretching exercises on lower limbs muscle cramps on the patients undergoing regular haemodialysis in study group when compared with control group. Experimental research design were adopted for the study; 126 patients undergoing regular haemodialysis in outpatient haemodialysis centre were randomly allotted for study and control groups i.e. 63 in each group. The patients’ muscle cramps was assessed using cramp questionnaire chart developed by Basemath SS Morris in both groups. Intradialytic stretching exercises were provided to the patients in the study group in each leg from their 3rd to 10th sitting. Post-assessment was carried out on their 4th, 7th, and 10th sitting in the study group and the control groups. The control group patients were received routine hospital care. The lower limb muscle cramps mean score was found improvement from pre-assessment lower limb muscle cramp mean score 4.11 to post-assessment 10th sitting means score 2.086 after intradialytic stretching exercise in the study group. The study result showed that in post-assessment the lower limb muscle cramps was much better among the patients in study group who received the intradialytic stretching exercise than the patients in the control group who received routine hospital care. Intradialytic stretching exercises are reducing the intensity of muscle cramps in patients undergoing haemodialysis
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Marotta, Paul J., Ivo W. Graziadei, and Cameron N. Ghent. "Muscle Cramps: A ‘Complication‘ of Cirrhosis." Canadian Journal of Gastroenterology 14, suppl d (2000): 21D—25D. http://dx.doi.org/10.1155/2000/214916.

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Muscle cramps are a common complaint in clinical practice. They are associated with various metabolic, endocrine, neurological and electrolyte abnormalities. A variety of hypotheses have been generated to explain the cause of muscle cramping, yet none has been able to support a consistent pathophysiological mechanism. Muscle cramps are painful, involuntary contractions of skeletal muscle. They occur frequently in individuals with cirrhosis, regardless of the etiology, and are thought to be a symptom of cirrhotic-stage liver disease. The pathophysiology of these cramps remains elusive; hence, a specific therapy has not been identified. Many therapeutic approaches have been offered, yet their efficacy, safety and mechanism of action remain poorly defined. This review defines muscle cramps and illuminates its prevalence in the cirrhotic individual. Current theories relating to the pathogenesis of muscle cramps are reviewed, and an overview of the various pharmacological agents that have had therapeutic success for this distressing and frustrating symptom is provided.
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Garosi, Laurent, and Robert J. Harvey. "Scottie cramp and canine epileptoid cramping syndrome in Border terriers." Veterinary Record 170, no. 7 (February 18, 2012): 186.4–187. http://dx.doi.org/10.1136/vr.e1127.

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Bandkar, Archana, and Adwait Darshetkar. "WRITERS CRAMP - A MAJOR CONUNDRUM: REVIEW ARTICLE." International Journal of Advanced Research 11, no. 12 (December 31, 2023): 683–89. http://dx.doi.org/10.21474/ijar01/18032.

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Background: Writers cramp (WC) is commonly seen in professional workers where writing is the main part of their work. It shows bimodal age of distribution, affects both genders.WC has an incidence rate of approximately 2.7 per million population.WC is diagnosed basically on clinical presentation and history.Functional improvement is the main aim of treatment in the case of WC.Treatment strategies consist of Pharmacological, Surgical, and Non-pharmacological strategies. Objectives: This article highlights clinical features, epidemiology, etiology, available treatment and cure rate with respect to available treatment strategies, and the impact of the writers cramp on the social, economic, and psychological behavior of patients. Methods: This literature has been compiled after scrutinized analysis and consultation with various neurologists along with thorough research from trusted and verified sources. Results: It is observed that patients with writers cramps start using their non-dominant hands to get relief from dystonia. In severe cases, dystonia occurs in non-dominant hands also after some time. Patients with writers cramps experience difficulty with day-to-day activities like writing, combing hair, and sewing. Conclusion: Very few recent studies are available for writers cramps and the sample size is also small. Treat Writers cramp patient as handicapped, require a large sample size, case-control study, long-duration follow up period.
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Dinehart, Matthew S., Stacy McMurray, Scott M. Dinehart, and Mark Lebwohl. "L-Carnitine Reduces Muscle Cramps in Patients taking Vismodegib." SKIN The Journal of Cutaneous Medicine 2, no. 2 (March 9, 2018): 90–95. http://dx.doi.org/10.25251/skin.2.2.1.

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Vismodegib is an oral, small-molecule hedgehog pathway inhibitor (HHI) approved for the treatment of locally advanced and metastatic basal cell carcinoma. While an effective treatment option for these conditions, HHI therapy is associated with muscle cramps in a significant number of patients. This adverse effect negatively impacts patient quality of life and patient adherence to the prescribed treatment regimen.Levocarnitine (L-carnitine) is a trimethylated amino acid known to play a critical role in lipid metabolism. It has antioxidant properties, and several studies have illustrated its effectiveness in lessening the severity of muscle cramps in various disease processes.We present three patients who developed muscle cramping associated with vismodegib treatment for basal cell carcinoma. Each was started on L-carnitine therapy, and all three reported a significant decrease in the severity of their muscle cramps to the point that they were able to continue HHI therapy without taking a drug holiday. These cases illustrate a promising treatment option for the most common side effect associated with HHI treatment.
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Durand, Pierre-Yves, Carole Nicco, Didier Serteyn, David Attaf, and Marvin Edeas. "Microbiota Quality and Mitochondrial Activity Link with Occurrence of Muscle Cramps in Hemodialysis Patients using Citrate Dialysate: A Pilot Study." Blood Purification 46, no. 4 (2018): 301–8. http://dx.doi.org/10.1159/000490612.

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Background/Aims: Hemodialysis-associated muscle cramp (HAMC) is a common complication under citrate dialysate (CD) occurring in 30% of cases. Our objectives were to assess the gut microbiota quality, mitochondrial activity, and to investigate their possible relationship with HAMC. Methods: Ten end-stage renal disease patients (78.9 ± 2.1 years) treated by hemodialysis (HD) with CD were enrolled and then classified according to the frequency of HAMCs: “frequent HAMCs group” (n = 5) and “absence of HAMCs group” (n = 5). Gut microbiota quality, mitochondrial activity, and some markers of oxidative stress (OS) were investigated. Results: In patients with cramps, gut microbiota diversity seemed lower and some genera including Helicobacter, Lachnospira, Roseburia, and Haemophilus seemed over-expressed, a significant increase of citratemia and significant lowering mitochondrial function were observed. No difference was observed on the OS markers. Conclusion: This first clinical study revealed a possible dysbiosis of microbiota and a mitochondrial dysfunction into HD patients with cramps under CD compared to patients without cramp.
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Winderickx, Sofie, Katrijn De Brucker, Matthew J. Bird, Petra Windmolders, Els Meert, Bruno P. A. Cammue, and Karin Thevissen. "Structure-activity relationship study of the antimicrobial CRAMP-derived peptide CRAMP20-33." Peptides 109 (November 2018): 33–38. http://dx.doi.org/10.1016/j.peptides.2018.08.013.

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Ghalaut P S and Meenal Babra. "Writer’s Cramp or Focal Dystonia- Case report of a Rare Neurological Disorder." International Journal of Research in Pharmaceutical Sciences 10, no. 4 (November 13, 2019): 3560–62. http://dx.doi.org/10.26452/ijrps.v10i4.1735.

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There are various neurological disorders which are clinically diagnosed and treated every day. Focal dystonia's such as Writer’s cramps or musician’s cramps is one such neurological disorder that is not very common, but if remains undiagnosed or not treated appropriately causes severe disability and anxiety to the patient. It not only hampers them emotionally and socially but also leads to professional problems. There are various treatment modalities available. Patients complain of spasm or cramping of muscles, which is sometimes associated with pain and inability to write or play an instrument which he/she used to play perfectly some time ago. Identifying this disorder and treating it in time can benefit the patient to a great extent. Though not a single treatment has turned successful in all patients. Some patients get relieved by behavioural therapy, while others respond to medical treatment.
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Cleary, Michelle, Daniel Ruiz, Lindsey Eberman, Israel Mitchell, and Helen Binkley. "Dehydration, Cramping, and Exertional Rhabdomyolysis: A Case Report with Suggestions for Recovery." Journal of Sport Rehabilitation 16, no. 3 (August 2007): 244–59. http://dx.doi.org/10.1123/jsr.16.3.244.

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Objective:We present a case of severe dehydration, muscle cramping, and rhabdomyolysis in a high school football player followed by a suggested program for gradual return to play.Background:A 16-year-old male football player (body mass = 69.1 kg, height = 175.3 cm) reported to the ATC after the morning session on the second day of two-a-days complaining of severe muscle cramping.Differential Diagnosis:The initial assessment included severe dehydration and exercise-induced muscle cramps. The differential diagnosis was severe dehydration, exertional rhabdomyolysis, or myositis. CK testing revealed elevated levels indicating mild rhabdomyolysis.Treatment:The emergency department administered 8 L of intravenous (IV) fluid within the 48-hr hospitalization period, followed by gradual return to activity.Uniqueness:To our knowledge, no reports of exertional rhabdomyolysis in an adolescent football player exist. In this case, a high school quarterback with a previous history of heat-related cramping succumbed to severe dehydration and exertional rhabdomyolysis during noncontact preseason practice. We provide suggestions for return to activity following exertional rhabdomyolysis.
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Georgieva, Julia, Carly J. Brade, Kagan J. Ducker, Paul Davey, Angela Jacques, Masato Ohno, and Andrew P. Lavender. "Effectiveness of Mouth Rinsing versus Ingesting Pickle Juice for Alleviating Electrically Induced Cramp in Physically Active Adults." Applied Sciences 11, no. 24 (December 19, 2021): 12096. http://dx.doi.org/10.3390/app112412096.

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(1) Background: Stimulating oropharyngeal transient receptor potential (TRP) channels inhibits muscle cramping by triggering a supraspinal reflex to reduce α-motor neuron hyperexcitability. This study investigated whether the longer stimulation of the TRP channels via mouth rinsing with PJ is more effective than drinking PJ at inhibiting an electrically induced muscle cramp (EIMC). Both conditions were compared to the control (water). (2) Methods: The tibial nerves in 11 cramp-prone adults were percutaneously stimulated to elicit an EIMC of the flexor hallucis brevis in three trials that took place one week apart from each other. At cramp onset, the participants received mouth rinsing and expelling PJ (25 mL), ingesting PJ (1 mL∙kg−1 body-mass (BM)), or ingesting water (1 mL∙kg−1 BM). Cramp onset and offset were induced by electromyography, and the severity of discomfort was recorded using a visual analogue scale (VAS). (3) Results: The median time to cramp cessation as a percentage of water was 82.8 ± 14.63% and 68.6 ± 47.78% for PJ ingestion and PJ mouth rinsing, respectively. These results had large variability, and no statistically significant differences were observed. There were also no differences in perceived cramp discomfort between conditions, despite the hazard ratios for the time taken to reach VAS = 0, which was higher than water (control) for PJ ingestion (22%) and mouth rinsing (35%) (p = 0.66 and 0.51, respectively). (4) Conclusions: The data suggest no difference in cramp duration and perceived discomfort between PJ and water.
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Jogindra, Vati. "Effectiveness of intradialytic leg stretching exercises to reduce muscle cramps among patients undergoing hemodialysis." i-manager’s Journal on Nursing 11, no. 4 (2022): 16. http://dx.doi.org/10.26634/jnur.11.4.18325.

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Muscle cramp is one of the most frequent problems experienced by patients during hemodialysis who have low functional capacity, decreased muscle strength, and fatigue and are associated with poor health-related quality of life. Providing exercises reduce muscle cramps by improving muscle strength and flexibility. Workouts also increase blood flow and open capillary surface areas, thereby increasing waste removal. To evaluate the effectiveness of intradialytic exercises to reduce the frequency and intensity of muscle cramps among patients undergoing hemodialysis, a preexperiment, one group pre-test, and a post-test study were conducted on 60 patients who confirmed the inclusion and exclusion criteria recruited consecutively. A structured interview schedule, self-developed muscle cramps assessment proforma, and visual analogue scale were used after getting approved by the ethical committee and taking permission from hospital authorities. Intradialytic active and passive leg exercises were performed as per the developed protocol. A post-test was conducted after a follow-up period of 6 weeks. Data analysis was done using descriptive and inferential statistics. The result shows a significant decrease in the frequency and pain intensity of muscle cramps after exercise. There was no significant association of muscle cramps with the selected socio-demographic and clinical variables, except in post-intervention with sedentary lifestyles. The muscle cramps were more among patients with sedentary lifestyles than non-sedentary. Intradialytic stretching leg exercises were highly effective in reducing muscle cramps' frequency and pain intensity. Nurses must include this program as a part of routine care for all patients after assessing risks subjected to hemodialysis.
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Ramos-Daguman, Krizia Mari Anne, Ed Jico Conde, Henry Angelo Go, Vince Bryan Viscayno, Monalisa Lim Dungca, and Marissa Elizabeth Lim. "Intradialytic massage for leg cramps among hemodialysis patients: A single-center, randomized crossover trial." SciEnggJ 17, Supplement (April 24, 2024): 131–38. http://dx.doi.org/10.54645/202417supejr-14.

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Background: Leg cramps are commonly experienced by hemodialysis patients, and its persistence may lead to treatment noncompliance. Limited studies are available examining the efficacy of intradialytic massage on reducing leg cramps. Objectives: To determine the efficacy of intradialytic leg massage on reducing leg cramps among patients undergoing maintenance hemodialysis at the East Avenue Medical Center. Methodology: This is a single-center, randomized crossover trial. A total of 44 adult patients were randomized in a 1:1 ratio into two groups—Group A (intradialytic massage followed by control) and Group B (control followed by intradialytic massage). Each patient underwent the first assigned intervention for 2 weeks, followed by a washout period of 4 weeks, then the second intervention was performed for another 2 weeks. The primary outcomes were the change in frequency, duration, and intensity of cramps. The secondary outcome was patient quality of life. Results: A higher proportion of patients during the intervention period did not experience cramps post-intervention than during the control period; however, the results were not statistically significant (p=0.2059). The median change in frequency, duration, and intensity of leg cramps did not significantly differ between intervention and control (p>0.05). Moreover, quality of life measures were not significantly different between the two groups (p>0.05). Conclusion: Intradialytic massage alone is not efficacious in reducing leg cramp frequency, duration, and intensity. Moreover, intradialytic massage failed to improve the quality of life of patients undergoing hemodialysis treatment. Underlying factors that lead to leg cramps should be addressed through comprehensive and individualized interventions.
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Weller, J. "Gillian Mary Crampton." BMJ 349, no. 24 9 (November 24, 2014): g6857. http://dx.doi.org/10.1136/bmj.g6857.

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Jobe, Ronald A. "Profile: Patricia Crampton." Language Arts 65, no. 4 (April 1, 1988): 410–14. http://dx.doi.org/10.58680/la198825037.

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Panza, Gino, Justin Stadler, Donal Murray, Nicholas Lerma, Tomas Barrett, Ryan Pettit-Mee, and Jeffrey E. Edwards. "Acute Passive Static Stretching and Cramp Threshold Frequency." Journal of Athletic Training 52, no. 10 (October 1, 2017): 918–24. http://dx.doi.org/10.4085/1062-6050-52.7.03.

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Context: Exercise-associated muscle cramps are a common clinical problem for athletes. Objective: To determine whether acute passive static stretching altered cramp threshold frequency (CTF) of electrically induced muscle cramps. Design: Crossover study. Setting: Laboratory. Patients or Other Participants: Seventeen healthy college-aged individuals. Intervention(s): Stretching or no stretching. Main Outcome Measure(s): The independent variable was the static stretch versus the no-stretch condition, and the dependent variable was the CTF. Results: The CTF increased in both the control (pretest: 18.12 ± 6.46 Hz, posttest: 19.65 ± 7.25 Hz; P = .033) and stretching (pretest: 18.94 ± 5.96 Hz, posttest: 20.47 ± 7.12 Hz; P = .049) groups. No difference between the groups was found (t15 = 0.035, P = .97). Conclusions: Acute passive static stretching did not seem to increase the CTF.
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Finsterer, Josef, and Marlies Frank. "Low-Glycemic-Index Diet Relieving Migraine but Inducing Muscle Cramps." Journal of Neurosciences in Rural Practice 10, no. 03 (July 2019): 552–54. http://dx.doi.org/10.1055/s-0039-1698034.

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AbstractLow-glycemic-index diet (LGID) has been shown to exhibit a beneficial effect in patients with epilepsy, exercise-induced dyskinesia, writer's cramp, migraine, and in myopathic mice. A 57-year-old female with classical migraine with and without aura since 14 years of age and a frequency of 8 to 12 attacks per month experienced some relief using a nasal spray of zolmitriptan since 10 years. Occasionally, she developed a status migrainosus lasting up to 5 days. At the age of 57 years, she started an LGID and recognized a significant decline of frequency and intensity of her migraine attacks but also of other abnormalities shortly after starting the diet. After 8 weeks on the LGID muscle cramps of the left calve, which radiated to the thighs, buttocks, and from there to the right leg, accompanied by fasciculations developed. The slight modification of the LGID, naproxen, and novaminsulfon relieved the cramps. LGID may have a beneficial effect on classical migraine but may induce muscle cramps, which require modification of the LGID.
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Scahill, Shane. "Potion or Poison? Magnesium for muscle cramps." Journal of Primary Health Care 5, no. 3 (2013): 253. http://dx.doi.org/10.1071/hc13253.

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SUMMARY MESSAGE: The literature is conflicting with regard to the effectiveness of magnesium in the setting of pregnancy-related cramps at rest. Based on supporting data, it is unlikely that magnesium supplementation provides clinically meaningful cramp prophylaxis to older adults. There is no more than anecdotal evidence to support combination magnesium and other vitamins and minerals available over the counter. Magnesium supplementation is generally well tolerated in therapeutic doses, except in renal impairment.
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Prier, Jillian, Kristin Phipps, and Maha Alattar. "1223 REM-related Leg Cramps." SLEEP 47, Supplement_1 (April 20, 2024): A521. http://dx.doi.org/10.1093/sleep/zsae067.01223.

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Abstract Introduction Nocturnal leg cramps are common in the general population and is reported in 30% of adults. It is described under sleep related movement disorders in the International Classification of Sleep Disorders. It is a painful sensation in the legs that occurs during sleep or out of sleep but is not necessarily associated with a particular stage of sleep, relieved by stretching. We present a case of nocturnal leg cramps occurring during REM sleep. Report of case(s) Patient is a 53-year-old female reporting a history of waking from sleep with leg cramps. She underwent a CPAP titration study at our facility for a previously documented obstructive sleep apnea (AHI of 28, REM AHI of 74.1). On video, she was seen to wake abruptly out of each of the three REM sleep episodes, sitting and rubbing her calves, and reporting to the technician that she was having leg cramps. She would then get up and walk around to relieve the cramps but was able to return to sleep. Each episode lasted 3-5 minutes and was only relieved with movements or massage. No leg cramps were reported from non-REM sleep during this study. She denied symptoms of restless legs syndrome. Her periodic limb movements of sleep indices during her diagnostic and CPAP polysomnograms were 2.0 and 5.1 respectively and occurred during non-REM sleep. Medical history includes asthma and COPD (oxygen supplementation as needed), heart disease, prior polysubstance use disorder, and treated infective endocarditis in 2011. Conclusion Our case characterizes nocturnal leg cramps that occurred at a particular sleep stage, in this case strictly during REM sleep. Nocturnal leg cramps have been reported in the literature in association with various medical comorbidities including vascular disease and OSA. Further, it has been reported that CPAP therapy for OSA results in near or total elimination of leg cramp burden. It is unclear what is the mechanism of REM-related leg cramps, but it could be the REM OSA. To our knowledge, this is the first documented case of REM-related nocturnal leg cramps. We hope to add to the present literature on the mechanism of this disorder. Support (if any)
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Pal, Rashmi Saxena, Yogendra Pal, Pranay Wal, Nikita Saraswat, and Ankita Wal. "A Novel Approach on Review of Herbal Menstrual Cramps Relievers." Current Women s Health Reviews 15, no. 3 (April 1, 2019): 179–87. http://dx.doi.org/10.2174/1573404815666190110102659.

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Background: Menstrual cramps is the occurrence of labor-like pain in the lower abdomen, accompanied by symptoms like nausea, vomiting, diarrhea, headache and dizziness. A natural approach towards the treatment of painful menstruation is the need of the hour to be imparted in mind/body practices to be considered for long-term relief from the pain of menstrual cramp forever. Objective: The current research is aimed at the review of the various aspects of plant alternates serving in different ways to relieve the cramps occurring in menstruation. Materials and Methods: The herbal alternates as relievers were categorized on the basis of the respective role being played by them as nutritional supplements, analgesics, anti-inflammatory and as aromatherapy agents. Results: There are various plant sources which are mild as well as effective relievers of menstrual cramps. This review highlights the various plants which have been proven to be useful in dealing with the various issues of painful menstruation. They deal with all the complications and issues, arising during this time. Conclusion: These herbs are a potent source of active medicaments that strengthens the body to overcome the cramps and pain occurring in menstruation. The demand of the present hour is to rely on the beneficial effects of various herbs, which relieve these complications in the most soothing and efficacious manner.
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Bolla, Rishi, Cynthia Bodkin, Marwan Ghabril, Naga Chalasani, and Raj Vuppalanchi. "Investigation of Muscle Cramps in Patients With Cirrhosis Using Electrical Stimulation Cramp Threshold Frequency." American Journal of Gastroenterology 113, Supplement (October 2018): S577—S579. http://dx.doi.org/10.14309/00000434-201810001-01021.

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Miller, Kevin C., and Kenneth L. Knight. "Electrical stimulation cramp threshold frequency correlates well with the occurrence of skeletal muscle cramps." Muscle & Nerve 39, no. 3 (March 2009): 364–68. http://dx.doi.org/10.1002/mus.21170.

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Lau, Wing Yin, Haruyasu Kato, and Kazunori Nosaka. "Water intake after dehydration makes muscles more susceptible to cramp but electrolytes reverse that effect." BMJ Open Sport & Exercise Medicine 5, no. 1 (March 2019): e000478. http://dx.doi.org/10.1136/bmjsem-2018-000478.

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ObjectiveNo previous study has compared water and oral rehydration solution (ORS) intake after dehydration induced by exercise in the heat for the effect on muscle cramps. The present study tested the hypothesis that water ingestion after dehydration would increase muscle cramp susceptibility, but this would be prevented by ORS ingestion.MethodsTen men performed two bouts of downhill running (DHR; −5%) in the heat (35°C–36 °C) until their body mass was reduced by 2%. Ten minutes after DHR, either spring water or electrolyte water similar to ORS (OS-1®) was ingested in a counter-balanced order on two different days separated by a week. Muscle cramp susceptibility was assessed by a threshold frequency (TF) of electrical train stimulation to induce cramp before, immediately after (0), and 30 and 60 min after the ingestion. Blood samples were taken before, immediately and 80 min after DHR to measure serum electrolyte concentrations.ResultsMuscle cramp susceptibility assessed by TF did not change from baseline to immediately after DHR for both conditions (water: 24.6 ± 2.1 Hz, OS-1®: 24.7 ± 1.4 Hz). TF decreased after water intake by 4.3 Hz (30 min) and 5.1 Hz (60 min post-ingestion), but increased after OS-1®intake by 3.7 and 5.4 Hz, respectively. Serum sodium and chloride concentrations decreased after water intake but maintained after OS-1®intake.ConclusionThese results suggest that water intake after dehydration makes muscles more susceptible to electrical simulation-induced muscle cramp, probably due to dilution of electrolytes, and when OS-1®is consumed, the susceptibility to muscle cramp decreases.
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Fukaya, Chikashi, Yoichi Katayama, Toshikazu Kano, Takafumi Nagaoka, Kazutaka Kobayashi, Hideki Oshima, and Takamitsu Yamamoto. "Thalamic deep brain stimulation for writer's cramp." Journal of Neurosurgery 107, no. 5 (November 2007): 977–82. http://dx.doi.org/10.3171/jns-07/11/0977.

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Object Writer's cramp is a type of idiopathic focal hand dystonia characterized by muscle cramps that accompany execution of the writing task specifically. In this report, the authors describe the clinical outcome after thalamic deep brain stimulation (DBS) therapy in patients with writer's cramp and present an illustrative case with which they compare the effects of pallidal and thalamic stimulation. In addition to these results for the clinical effectiveness, they also examine the best point and pattern for therapeutic stimulation of the motor thalamus, including the nucleus ventrooralis (VO) and the ventralis intermedius nucleus (VIM), for writer's cramp. Methods The authors applied thalamic DBS in five patients with writer's cramp. The inclusion criteria for the DBS trial in this disorder were a diagnosis of idiopathic writer's cramp and the absence of a positive response to medication. The exclusion criteria included significant cognitive dysfunction, active psychiatric symptoms, and evidence of other central nervous system diseases or other medical disorders. In one of the cases, DBS leads were implanted into both the globus pallidus internus and the VO/VIM, and test stimulation was performed for 1 week. The authors thus had an opportunity to compare the effects of pallidal and thalamic stimulation in this patient. Results Immediately after the initiation of thalamic stimulation, the neurological deficits associated with writer's cramp were improved in all five cases. Postoperatively all preoperative scale scores indicating the seriousness of the writer's cramp were significantly lower (p < 0.001). In the patient in whom two DBS leads were implanted, the clinical effect of thalamic stimulation was better than that of pallidal stimulation. During the thalamic stimulation, the maximum effect was obtained when stimulation was applied to both the VO and the VIM widely, compared with being applied only within the VO. Conclusions The authors successfully treated patients with writer's cramp by thalamic DBS. Insofar as they are aware, this is the first series in which writer's cramp has been treated with DBS. Thalamic stimulation appears to be a safe and valuable therapeutic option for writer's cramp.
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Bagchi, Ipsita. "Effectiveness of Intradialytic Stretching Exercise on Pain due to Muscle Cramps among Patients Undergoing Haemodialysis at a Selected Tertiary Care Hospital Bhubaneswar, Odisha." Nursing Journal of India CXI, no. 02 (2020): 85–90. http://dx.doi.org/10.48029/nji.2020.cxi207.

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Among the patients undergoing haemodialysis, complication of muscle cramps, commonly occurs in calf muscles, feet, toes and thigh. Stretching exercises are the best measure to reduce or prevent cramps from occurring during haemodialysis among chronic renal failure patients. In this study to evaluate the effectiveness of intra dialytic stretching exercise on pain due to muscle cramps among haemodialysis patient, randomised controlled clinical trial design was adopted; 162 patients, undergoing dialysis at Pradyumna Bal Memorial Hospital, Bhubaneswar were selected by consecutive sampling technique and according to randomisation table, divided into (1) control group (n=81) receiving only standard institutional protocol with 0.9% normal saline, at the onset of muscle cramps, during haemodialysis and (2) experimental group (n=81) receiving passive intradialytic stretching exercises, at the onset of pain, during haemodialysis for 15 minutes, once per sitting and the same was repeated for 3 such sittings. Pre-test pain score and post-test pain score at the end of each sitting, for both the group was recorded. Statistical ndings (independent t-test) revealed that in day 3 post-test mean score of pain due to muscle cramp in experimental group and control group were 1.74 & 4.15 respectively with difference of pre-test and post-test score in experimental group and control group were 7.04 & 4.87 respectively which was found to be statistically signi cant (p<0.05). After intra dialytic stretching exercise, a signi cant level of reduction in pain due to muscle cramps was noticed among patients undergoing haemodialysis. Participants felt comfortable and also expressed high level of satisfaction towards administration of stretching exercise.
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Steichen, O., and A. Ameri. "Crampes." EMC - Traité de médecine AKOS 5, no. 3 (January 2010): 1–8. http://dx.doi.org/10.1016/s1634-6939(10)49845-2.

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45

Kalsoom, Hira, Haseeb Mukhtar, and Rizwana Kilchew Latif. "Exercise induced muscle weakness in a young adult: McArdle’s disease unusual presentation." Journal of the Pakistan Medical Association 73, no. 12 (November 28, 2023): 2473–75. http://dx.doi.org/10.47391/jpma.8401.

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McArdle’s disease (Glycogen storage disease type V) is a rare inherited autosomal recessive disease involving defect in enzyme, glycogen phosphorylase (PYGM) which results in accumulation of glycogen mainly affecting skeletal muscles. It commonly presents in childhood and rarely in adults with symptoms like exercise intolerance, muscle weakness, cramps and fatigue. Herein, we report an unusual case of a 22 years old male in Pakistan with probable McArdle’s Disease presenting with repeated episodes of generalized cramping muscle pain, exercise intolerance and haematuria. The diagnostic approach to identifying this disease as well as the differentials of other rare types of skeletal muscle disorders that should be kept in mind while dealing with a similar clinical picture, irrespective of the age of presentation, have been discussed. Keywords: Glycogen Storage Disease Type V, Myoglobinuria.
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Zeng, Xue Lei, Bao Sou Sun, Xue Dao Shu, Wen Fei Peng, and Pei Sun. "Crampoon Parametrization Design Based on Further Development of SolidWorks." Applied Mechanics and Materials 201-202 (October 2012): 317–20. http://dx.doi.org/10.4028/www.scientific.net/amm.201-202.317.

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SolidWorks is a popular 3D design software.The characteristics and developing methods of SolidWorks which 3D design software are introduced, and studies the process of parametric design on SolidWorks software by using VB programming language, as well as the technologies of elaborating the program with API functions. And then combine with the crampoon elaborating the principle of process-driven method. When designing the large crampoon, we use the parametric design method to auto-form the 3D target crampoon model by constructing a interface software protype with which the crampoon demension parameters can be converted into some related program variables. That method not only improves the crampoon design efficiency and accuracy, but also provides some useful referenced experience to parametrical system design of other parts. Parametrization design has a wide application prospect in the field of mechanical parts designing.
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Berrick, Jill Duerr. "A Response to David Crampton." Social Service Review 81, no. 2 (June 2007): 347–49. http://dx.doi.org/10.1086/513116.

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GOLDSTEIN, ROBERT JUSTIN. "Bulgaria By R. J. Crampton." History 93, no. 311 (July 2008): 451–52. http://dx.doi.org/10.1111/j.1468-229x.2008.431_55.x.

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Lloyd, Lewis E. "Earle Wilcox Crampton (1895–1983)." Journal of Nutrition 115, no. 2 (February 1, 1985): 151–58. http://dx.doi.org/10.1093/jn/115.2.151.

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50

Stojakovic, Natasa, and Rajko Igic. "Simvastatin-induced nocturnal leg pain disappears with pravastatin substitution." Srpski arhiv za celokupno lekarstvo 141, no. 5-6 (2013): 387–89. http://dx.doi.org/10.2298/sarh1306387s.

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Introduction. Statins have similar side effects that do not always occur at the same rate among the various statins. We present a case of simvastatin-induced muscle toxicity that disappeared when pravastatin was substituted for the original drug. Case Outline. A 74-year-old male, a nonsmoker, complained of severe nocturnal leg cramps. The patient also complained that similar painful cramping occurred when he walked rapidly or jogged. Because some components of his lipid panel exceeded the ?desirable? range, and as he had a history of myocardial infarction, his family physician prescribed simvastatin (40 mg/day). The patient had taken this medication for the past eight years. The painful nocturnal episodes started two years ago and affected either one or the other leg. Four months ago we discontinued his simvastatin and prescribed pravastatin (80 mg/day). At a follow-up visit six weeks later, the patient reported that his leg pains at night and the pain experienced after brisk walking had disappeared. Four months after the substitution of pravastatin for simvastatin, the patient reported that his complete lack of symptoms had continued. Conclusion. These painful muscle cramps were probably caused by an inadequate vascular supply to the calf and foot muscles. Perhaps a combination of advanced age and atherosclerotic changes created a predisposition for the simvastatin-induced leg cramps. Pravastatin differs from simvastatin in several ways. It is not metabolized by cytochrome P450 (CYP) 3A4 oxidases, and thus is not influenced by CYP 3A4 inhibitors like simvastatin. Also, simvastatin is associated with single-nucleotide polymorphisms located within the SLCO1B1 gene on the chromosome 12 and established myopathy, while pravastatin lacks this association. These differences may contribute to increased tolerance to pravastatin in this particular case.

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