Дисертації: "Crampon"

1

Fahey, Nicholas J. S. B. Massachusetts Institute of Technology. "A flexible crampon design." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/32975.

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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2005.
Includes bibliographical references (leaf 16).
The design of crampons is studied and a new, more comfortable, flexible crampon design is proposed. A brief history of crampons is provided and then the current state of crampon design is discussed. Two major problems in modern crampons were identified. The first big problem was that the crampons are extremely hard to use and adjust especially in cold, wet conditions. The second problem was the comfort of the crampons on the hikers feet. While this issue may seem somewhat trivial, when hikers are on a multi-day expedition they need to keep their feet in the best possible condition. Therefore, a crampon design that makes use of larger safety straps operable by a person wearing gloves is proposed. The center of the crampon itself is flexible, being made from spring steel. This allows the crampon to flex with a hiker's foot, thereby improving walking comfort.
by Nicholas Fahey.
S.B.

2

Karamanoukian, Alexandre. "Développement d'un outil de quantification de la charge mécanique en football à partir de crampons instrumentés de capteurs de force : vers une application à la prévention des blessures." Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASW009.

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La majorité des blessures en football interviennent sans contact avec un autre joueur, les lésions musculaires étant prépondérantes. La fatigue (et les perturbations neuromusculaires qu'elle induit) ainsi que la gestion de la charge d'entraînement ont été identifiées dans la littérature comme les principaux facteurs de risques de blessures, ces dernières étant plus nombreuses en fin de match et lors des semaines plus chargées en termes de compétition. Malgré le développement récent de nombreux outils de suivi, le maintien des blessures à un niveau important au cours des deux dernières décennies interroge l'efficacité des stratégies actuelles de prévention des blessures. Plus particulièrement, le manque d'outil valide permettant d'estimer les impacts et les forces endurées par les joueurs induit une estimation incomplète de la fatigue musculo-squelettique.Le développement d'une paire de chaussures dotée de crampons instrumentés permettant de mesurer les forces de réaction du sol représente donc une innovation pouvant permettre de dépasser ces limites.La première étape de ce travail avait pour objectif de valider scientifiquement cette nouvelle technologie, à la fois sur le terrain et en laboratoire. Les résultats ont démontré un très haut degré d'accord entre les données issues des crampons instrumentés et celle de la plateforme de force, permettant de valider scientifiquement cet outil.La deuxième étape de ces travaux avait pour but d'étudier les variations des paramètres dynamiques et spatio-temporels enregistrés à l'aide de la chaussure à crampons instrumentés sur le terrain lors d'une course à vitesse constante jusqu'à épuisement. Des variations significatives ont été relevées chez l'ensemble des sujets, démontrant ainsi l'utilité de cet outil pour détecter et quantifier la fatigue aigüe sur le terrain. De plus, l'amplitude et le sens de ces changements ont démontré une grande variabilité inter-individuelle.Enfin, la troisième étape de ces travaux consistait à mesurer ces variations de manière longitudinale, tout au long de la saison, chez un public professionnel. La nature de ces variations a ensuite été utilisée afin d'estimer la fatigue musculo-squelettique induite par un entraînement. La répétition de ce protocole, simple à mettre en œuvre, nous a ainsi permis de rendre plus précise la quantification de la fatigue musculo-squelettique au cours de l'année
The majority of injuries in football are non-contact injuries, with muscular strains being the most common. Fatigue and excessive training load are known risk factors, with injuries being most frequent at the end of matches and during overloaded weeks. Despite recent improvements in training load and fatigue monitoring, injury burden remained stable during the last two decades, raising questions about the efficiency of injury prevention strategies. More specifically, the lack of valid tools to estimate ground reaction forces (GRFs) and impacts sustained by players leads to an incorrect biomechanical load/fatigue estimation.The development of instrumented studs (IS) capable of recording on-field GRFs represent, therefore, a major breakthrough.The first step of this study was to assess the validity of a pair of football shoes fitted with IS. The results demonstrated that this tool is a highly valid device for obtaining on-field GRFs.The second aim of this study was to examine the kinetic and spatio-temporal parameters adaptations induced by an exhaustive on-field run at constant with the help of IS. Significant changes were found among all subjects, thus proving the usefulness of this tool to measure fatigue in situ. Results also demonstrated some large inter-individual variability.Finally, the third aim was to assess these changes among professional players throughout a competitive football season. The nature of these variations was then used to estimate biomechanical fatigue induced by training. Repeating this simple procedure throughout the year allowed us to better estimate players' biomechanical

3

Langbour, Nicolas. "Perturbations des processus d’intégration sensori-motrice dans la crampe de l’écrivain : une étude physiopathologique combinant imagerie par résonance magnétique fonctionnelle et électroencéphalographie-haute résolution." Thesis, Bordeaux 2, 2012. http://www.theses.fr/2012BOR21956/document.

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La crampe de l'écrivain est la forme la plus fréquente de dystonies de fonction. Elle se caractérise par l’apparition de contractions musculaires involontaires et soutenues aboutissant à une perturbation sévère de l’écriture. Cette dernière est une tâche motrice séquentielle complexe nécessitant un contrôle continu des informations proprioceptives afin d’adapter la position du membre supérieur et la pression des doigts sur le stylo au cours de l’activité motrice. Dans ce travail de thèse nous avons postulé que l’élément fondamental de la physiopathologie de la crampe de l’écrivain est un trouble de l’intégration sensori-motrice. Pour tester cette hypothèse, nous avons utilisé deux tâches comportementales n’induisant pas de symptôme dystonique. Le sujet devait exécuter une séquence motrice, soit de façon spontanée (tâche SGT), soit sur la base d’une séquence de stimulation tactile précédemment apprise (ST). Les modifications d’activité cérébrale au cours de ces deux tâches ont été étudiées par couplage des techniques d’imagerie par résonance magnétique fonctionnelle (IRMf) et d’électroencéphalographie quantitative (EEGq). Nos résultats suggèrent qu’en l’absence de symptôme dystonique, les patients atteints de crampe de l’écrivain présentent une altération de leur performance motrice dans les deux tâches. Durant l’analyse des informations proprioceptives, l’IRMf montre qu’il existe une diminution du signal Bold au niveau du cortex somesthésique primaire, de l’aire motrice supplémentaire (AMS) et du cortex pariétal. Les données d’EEGq révèlent une diminution de la désynchronisation β (DLEβ) au niveau de l’AMS et celles de la cohérence intra-corticale des perturbations du fonctionnement des réseaux pariéto-prémoteurs. Durant la phase motrice, l’IRMf ne révèle aucune différence inter-groupe, mais l’EEGq montre une augmentation de la DLEβ dans les régions pariétales postérieures pour la situation SGT, associée à une augmentation de cohérence intra-corticale. Après l’exécution du mouvement, des anomalies de synchronisation β (SLEβ) sont également retrouvées dans les deux tâches. Ces données montrent qu’il existe chez les patients présentant une crampe de l’écrivain, des perturbations de l’analyse séquentielle des informations proprioceptives, ainsi que des anomalies de l’intégration sensori-motrice. Elles sont en rapport avec une altération des relations fonctionnelles entre les cortex pariétaux et prémoteurs. Ces éléments expliquent pourquoi ces patients au cours de l’écriture ont des difficultés à élaborer une réponse motrice adaptée sur la base d’information proprioceptive séquentielle
Writer's cramp is the most frequent form of task-specific dystonia. It is characterized by excessive and inappropriate muscle activation resulting in severe disturbance of writing. Writing is a complex sequential motor task requiring the on-line continuous monitoring of proprioceptive information to adjust the position of the upper limb and finger pressure on the pen. In this experimental work, we postulated that the main feature in the pathophysiology of writer's cramp is a sensorimotor integration disorder. To test this hypothesis, we used two behavioral tasks that does not induce dystonic symptoms. The subject performed a motor sequence, either spontaneously (SGT task), or on the basis of a sequence of proprioceptive stimuli previously presented (ST). Changes in brain activity during both tasks were studied by coupling functional magnetic resonance imaging (fMRI) with quantitative electroencephalography (qEEG). Our results show that writer's cramp patients had impaired motor performances in both tasks whereas they did not exhibit any dystonic symptoms. During the analysis of proprioceptive information, fMRI shows a Bold signal decrease in the primary somatosensory cortex, the supplementary motor area (SMA) and parietal cortex. EEGq data revealed a decrease of β desynchronization (βERD) in SMA and intra-cortical coherence a disruption of the functional connectivity of parieto-premotor networks. During the motor phase, fMRI reveals no between-group difference, but EEGq showed an increase of βERD in the posterior parietal regions for the SGT task associated with an increased intra-cortical coherence. During the post-movement period, abnormal β synchronization (βERS) is also found in both tasks. This data shows that writer's cramp patient exhibited a disruption in the sequential analysis of proprioceptive information, as well as abnormalities in sensorymotor integration during motor planning. These features are related to an alteration of the functional relationships between the parietal and premotor cortices. These phenomenons explain why writer's cramp patient fail to develop an appropriate motor response on the basis of sequential proprioceptive information, as in writing

4

Jamora, Nelissa [Verfasser], Stephan von [Akademischer Betreuer] Cramon-Taubadel, Bernhard [Akademischer Betreuer] Brümmer, and Rico [Akademischer Betreuer] Ihle. "Price transmission in international rice markets / Nelissa Jamora. Gutachter: Stephan von Cramon-Taubadel ; Bernhard Brümmer ; Rico Ihle. Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2014. http://d-nb.info/1058477242/34.

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5

Steinhübel, Linda [Verfasser], Stephan Von [Akademischer Betreuer] Cramon-Taubadel, Stephan Von [Gutachter] Cramon-Taubadel, and Thomas [Gutachter] Kneib. "Urbanization, agricultural intensification, and environmental services: A spatial analysis / Linda Steinhübel ; Gutachter: Stephan Von Cramon-Taubadel, Thomas Kneib ; Betreuer: Stephan Von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2019. http://d-nb.info/1200634365/34.

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6

Schulze, Bisping Christin [Verfasser], Stephan von [Akademischer Betreuer] Cramon-Taubadel, Stephan von [Gutachter] Cramon-Taubadel, Bernhard [Gutachter] Brümmer, and Tatyana [Gutachter] Krivobokova. "Schätzverfahren für individuelles Preissetzungsverhalten im Lebensmitteleinzelhandel / Christin Schulze Bisping ; Gutachter: Stephan von Cramon-Taubadel, Bernhard Brümmer, Tatyana Krivobokova ; Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2018. http://d-nb.info/1150959975/34.

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7

Bleton, Jean-Pierre. "Les dystonies focales : leurs dysfonctionnements sensori-moteurs et leurs conséquences sur l'organisation du mouvement." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM4099.

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L’identification des muscles responsables des dystonies focales est un prérequis à l’instauration des traitements par toxine botulique et exercices correcteurs. A partir de deux dystonies apparemment dissemblables: la crampe de l’écrivain et la dystonie cervicale, nous avons montré que la réponse aux traitements est tributaire de la distribution des muscles impliqués. L’enregistrement des mouvements du segment tête-cou dans la dystonie cervicale , au moyen de capteurs inertiels 3-D, a montré qu’au mouvement volontaire de la tête, dans un plan, s’associent des mouvements non physiologiques dans les deux autres plans. Pour déterminer les actions musculaires en cause, nous avons réalisé une modélisation numérique du segment tête-cou permettant d’associer le muscle responsable aux déformations. Par ailleurs, sachant l’importance des phénomènes sensitifs dans le contrôle du mouvement, nous avons, au cours de tâches d’ajustement de la force musculaire, montré que ce contrôle de la force est perturbé dans chacune des deux dystonies focales étudiées.Nos résultats devraient avoir une implication dans les traitements symptomatiques de ces dystonies
The identification of the muscles responsible for focal dystonia is a prerequisite to the introduction of botulinum toxin treatment and tailored exercises. From two apparently dissimilar dystonia: writer's cramp and cervical dystonia, we showed that the response to the treatments depends on the distribution of the muscles involved. Recording the movement of the head-neck segment in cervical dystonia, using 3-D inertial sensors, showed that voluntary head movement in a plane is associated with non-physiological movement in the two other planes. To determine the muscular actions involved, we performed a digital modeling of the head-neck segment which allows us to link the responsible muscle with abnormal postures.Therefore, knowing the importance of sensory phenomena in the control of movement, we have, during tasks of muscular force adjustment, demonstrated that force control is altered in both studied dystonia.Our results should have implications in the symptomatic treatment of these dystonias

8

Schütte, Rebekka [Verfasser], Stephan von [Akademischer Betreuer] Cramon-Taubadel, Stephan von [Gutachter] Cramon-Taubadel, and Tobias [Gutachter] Plieninger. "Supporting biodiversity in European vineyards: Possibilities for winegrowers and economic implications / Rebekka Schütte ; Gutachter: Stephan von Cramon-Taubadel, Tobias Plieninger ; Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2019. http://d-nb.info/1196347344/34.

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9

Araujo, Enciso [Verfasser], Stephan von [Akademischer Betreuer] Cramon-Taubadel, Bernhard [Akademischer Betreuer] Brümmer, and Xiaohua [Akademischer Betreuer] Yu. "Economic Theory and Econometric Methods in Spatial Market Integration Analysis / Enciso Araujo. Gutachter: Stephan von Cramon-Taubadel ; Bernhard Brümmer ; Xiaohua Yu. Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2012. http://d-nb.info/1043765816/34.

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10

Hernández-Villafuerte, Karla [Verfasser], Stephan von [Akademischer Betreuer] Cramon-Taubadel, José M. [Akademischer Betreuer] Gil, and Bernhard [Akademischer Betreuer] Brümmer. "Price Transmission within selected Agricultural Markets of Latin America / Karla Hernández-Villafuerte. Gutachter: Stephan von Cramon-Taubadel ; José M. Gil ; Bernhard Brümmer. Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2012. http://d-nb.info/1043717366/34.

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Hernández-Villafuerte, Karla Verfasser], Stephan von [Akademischer Betreuer] [Cramon-Taubadel, José M. Akademischer Betreuer] Gil, and Bernhard [Akademischer Betreuer] [Brümmer. "Price Transmission within selected Agricultural Markets of Latin America / Karla Hernández-Villafuerte. Gutachter: Stephan von Cramon-Taubadel ; José M. Gil ; Bernhard Brümmer. Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2012. http://nbn-resolving.de/urn:nbn:de:gbv:7-webdoc-3635-7.

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12

Foschi, Juan Pablo Osvaldo, Di Cesare María Emilia Iniesta, and Marisa Concepción Muñoz. "Valuación de la empresa en el cramdown." Bachelor's thesis, Universidad Nacional de Cuyo. Facultad de Ciencias Económicas - Universidad Nacional de Cuyo. Facultad de Ciencias Económicas, 2011. http://bdigital.uncu.edu.ar/4608.

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Fil: Foschi, Juan Pablo Osvaldo. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.
Fil: Iniesta Di Cesare, María Emilia. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.
Fil: Muñoz, Marisa Concepción. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.

13

Sulzer, Nicole Uschi. "Exercise associated muscle cramping : investigating a novel hypothesis." Master's thesis, University of Cape Town, 2003. http://hdl.handle.net/11427/26321.

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This thesis on Exercise Associated Muscle Cramping (EAMC) comprised three individual studies. The aims of this series of investigations were firstly to investigate the nature and prevalence of EAMC in a group of lronman triathletes with a past history of EAMC, secondly to compare the serum electrolyte concentrations in cramping and control Ironman triathletes as well as to record the baseline electromyography (EMG) of cramping lronman triathletes during recovery and thirdly to compare the EMG activity of cramping and control runners before, during and after a fatiguing bout of exercise.

14

Drew, Nichola. "Exercise-associated muscle cramping (EAMC) in Ironman triathletes." Master's thesis, University of Cape Town, 2006. http://hdl.handle.net/11427/7428.

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Includes bibliographical references (leaves 73-77).
Exercise-associated muscle cramping (EAMC) is a common condition of spontaneous, painful skeletal muscle spasms that occur in exercising muscles during exercise or in the immediate post-exercise period. There is a high prevalence in endurance athletes, including ultra-distance triathletes. The exact cause for this condition has not been defined but various hypotheses have been proposed. Over the last decade the ""fatigue hypothesis"" has received most of the support in the scientific literature. Evidence from animal experiments, clinical studies on endurance athletes and situational information, suggest that neuromuscular fatigue may precede the increased neuromuscular excitability leading to EAMC. The objective of this research study was to identify factors associated with EAMC in endurance triathletes in an attempt to further elucidate the aetiology. Triathletes competing in the 2006 South African lronman triathlon were recruited as subjects in a prospective cohort study. A total of 44 triathletes made up the cramping group and 166 the non-cramping group. A detailed questionnaire, including information on training, personal best performances and a cramping history was completed by both groups of triathletes. Full clinical data was also collected from both groups. This included pre-and post race body weights, and pre- and post-race serum electrolyte concentrations. The main findings of the study were that the two independent risk factors for EAMC in these triathletes were a faster overall race time (and cycling time), and a past history of cramping (in the last 10 races). Results showed that EAMC was correlated with faster overall and cycle section times. The athletes who had experienced cramps in this event not only achieved taster race times but also predicted faster times, despite similarly matched preparation and performance histories as those who did not cramp. A higher intensity of racing would thus be required by these athletes, predisposing them to premature fatigue. The results thus agree with the ""fatigue hypothesis"" as an aetiological mechanism for EAMC. This study also showed no correlation between EAMC and changes in hydration status or changes in serum electrolyte concentration. This study thus adds to the evidence against disturbances in hydration and electrolyte balance as causes for cramping in exercise and further focuses attention on neuromuscular fatigue as a possible primary factor.

15

Hundeshagen, Cordula [Verfasser], Stephan von [Akademischer Betreuer] Cramon-Taubadel, Ulf [Akademischer Betreuer] Liebe, and Till [Akademischer Betreuer] Dannewald. "Preferences for Ethical Product Components: The Example of Jointly Produced Israeli-Palestinian Peace Products / Cordula Hundeshagen, geb. Wendler. Gutachter: Stephan von Cramon-Taubadel ; Ulf Liebe ; Till Dannewald. Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2014. http://d-nb.info/1052136109/34.

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16

Gonchigsumlaa, Ganzorig [Verfasser], Stephan von [Akademischer Betreuer] [Gutachter] Cramon-Taubadel, Bernhard [Gutachter] Brümmer, and Eva [Gutachter] Schlecht. "Competitiveness of pastoral livestock production and sea buckthorn farming in Mongolia: Application of Policy Analysis Matrix / Ganzorig Gonchigsumlaa. Betreuer: Stephan von Cramon-Taubadel. Gutachter: Stephan von Cramon-Taubadel ; Bernhard Brümmer ; Eva Schlecht." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2016. http://d-nb.info/1109046553/34.

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17

Pohl, Carey. "Exercise Associated Muscle Cramps in Cyclists : Epidemiology, clinical characteristics and risk factors." Diss., University of Pretoria, 2020. http://hdl.handle.net/2263/78530.

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Background: Exercise associated muscle cramping (EAMC) is a common medical condition encountered by endurance athletes, yet information regarding EAMC in cyclists in lacking. Aim of the study: To determine the epidemiology, clinical characteristics, and independent risk factors associated with EAMC in cyclists participating in a mass participation cycling event. Design: Cross-sectional study Setting: 2016 Cape Town Cycle Tour (CTCT), South Africa Participants: 22560 consenting cycle race entrants Methods: Epidemiological data (lifetime prevalence and annual incidence) and clinical characteristics (main muscle groups affected, timing of onset, severity [mild - severe] and frequency of serious forms of EAMC [sEAMC]) in cyclists with a history of EAMC (hEAMC) are reported on. A multiple regression analysis was applied in order to determine if the following factors were associated risk factors for EAMC in cyclists with a hEAMC: chronic disease composite score, cycling training / racing history (years of recreational cycling, years of participation in distance cycling events > 2 hours, average number of training sessions per week, average weekly cycling distance in the last 12 months, and average training speed), history of chronic disease (history of cardiovascular disease [CVD], risk factors for CVD, symptoms of CVD, metabolic/hormonal disease, respiratory disease, gastrointestinal disease, nervous system/psychiatric disease, kidney/bladder disease, haematological/immune system disease, and cancer) and allergies, and history of cycling injuries. Results: A total of 35914 cyclists entered the race, 27349 completed the online pre-race medical screening questionnaire, and 22560 gave informed consent for the use of their data in this study (62.82% of all race entrants). The lifetime prevalence of EAMC was 30.6%, with an annual incidence of 18.7%. The quadriceps muscle group was the most commonly affected muscle group (47.7%), the most common time period for the onset of EAMC was during the fourth quarter of the race (63.0%), and mild (less than 5 minutes) EAMC occurred more frequently (67.0%) than other forms of EAMC. Serious EAMC was reported by 5.6% of the study population, and included whole body EAMC (3.2%) and EAMC associated with dark urine (2.2%). Novel independent risk factors associated with an increased risk of hEAMC in cyclists were: a higher chronic disease composite score (PR=1.34 per 2 unit increase; p<0.0001), a history of any allergies (PR=1.17; p<0.0001), a history of an acute onset injury (PR=1.31; p<0.0001), a history of a gradual onset injury (PR=1.29; p<0.0001), and increased number of years participating in cycling events of > 2 hours (PR=1.34 per 2 unit increase, p<0.0001). Increased number of years as a recreational cyclist (PR=0.96 per 5 unit increase, p=0.0012) and increased average weekly training/racing frequency in the last 12 months (PR=0.95 per 2 unit increase, p=0.0015) were associated with a decreased risk of EAMC. From the univariate analysis, we identified a significantly higher prevalence of lifetime hEAMC in male cyclists (PR=2.16; p<0.0001), and a higher prevalence of hEAMC in the ≥51-year age category (37.6%). Conclusion: One in three cyclists report a lifetime hEAMC. In cyclists with a hEAMC, the quadriceps muscle group is the most commonly affected muscle group, EAMC commonly occurs in the last quarter of the race, most EAMC cases are reported as mild, and sEAMC is not common. The results from this study could influence the future prevention and management programmes of EAMC in recreational cyclists, and assist medical personnel in the planning and implementation of medical care at mass participation cycling events. A higher chronic disease composite score, a history of allergies, a history of injury (acute onset or gradual onset) and training / racing variables are novel independent risk factors associated with a hEAMC in cyclists taking part in a mass participation cycling event. Risk factors for EAMC need to be taken into consideration when implementing prevention and management programmes of EAMC in cyclists. Clinicians should also consider that in some cases, EAMC may be associated with underlying chronic diseases or allergies, and/or the medications used to treat such conditions. In addition, injury history and training variables need to be considered in the prevention and management of EAMC in cyclists. Keywords: muscle cramping, exercise associated muscle cramping, EAMC, cyclists, clinical characteristics, epidemiology, risk factors, chronic disease
Dissertation (MPhysiotherapy)--University of Pretoria, 2020.
Physiotherapy
MPhysiotherapy
Restricted

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AURRENS, MOURENS VERONIQUE. "Circonstances de survenue d'une dystonie de fonction a type de crampe de l'ecrivain : a propos de 50 cas." Aix-Marseille 2, 1990. http://www.theses.fr/1990AIX20289.

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19

Mengel, Carolin Simone [Verfasser], Stephan von [Akademischer Betreuer] Cramon-Taubadel, Bernhard [Akademischer Betreuer] Brümmer, and Sebastian [Akademischer Betreuer] Heß. "Determinants of price transmission / Carolin Simone Mengel. Gutachter: Bernhard Brümmer ; Sebastian Heß. Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2014. http://d-nb.info/1058250442/34.

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20

Garrison, Scott Russel. "An exploration of new therapeutic options for nocturnal leg cramps." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/42957.

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THE PROBLEM: Rest cramps (also known as nocturnal leg cramps) are painful muscle contractions, typically in the legs or feet, that occur during prolonged rest - most often while in bed at night. Although common in older adults, safe and effective treatment options are lacking. OPPORTUNITY AND METHOD #1: Magnesium supplements are readily available and widely marketed to consumers for cramp prophylaxis. However the efficacy of magnesium for this indication is unclear and existing clinical trials are limited by the well recognized poor bioavailability of oral magnesium. To better assess the potential efficacy of magnesium in cramp prophylaxis I conducted a (N=46) double-blind, placebo-controlled RCT on community-dwelling rest cramp sufferers to determine whether a more reliable delivery method (5 consecutive days intravenous infusion of 20 mmol magnesium sulfate) could reduce the frequency of rest cramps. I additionally determined whether the response to treatment varied with the extent to which infused magnesium was retained (as measured by 24-hr urinary magnesium excretion) and performed a Cochrane Systematic Literature Review to find and synthesize all relevant randomised trials. OPPORTUNITY AND METHOD #2: Anecdotal evidence suggested several medications might promote muscle cramping. If true, cramp sufferers using these drugs could potentially gain cramp relief through therapeutic substitution or reduction of these agents. To investigate this potential cramp link I searched BC Ministry of Health databases containing diagnostic and prescribing information on the 4.2 million residents of British Columbia to determine, using sequence symmetry methods, whether quinine starts (i.e. new cramp treatment) increased in the year following introduction of the three most commonly prescribed medications with a link to muscle cramps (diuretics, statins and inhaled long-acting beta2-agonists). CONCLUSION: Although its role in pregnancy-associated rest cramps remains unclear, magnesium supplementation does not meaningfully reduce the frequency of rest cramps in older adults. Alternatively, for some cramp sufferers, reduction or discontinuation of select cramp promoting medications (inhaled long-acting beta2-agonists, potassium-sparing diuretics and thiazides) may be a useful therapeutic maneuver. Over a 13 year period 60.3% of quinine users (cramp sufferers) received at least one of these medications. In contrast, statin and loop-diuretic cramp associations were clinically unimportant.

21

Hallissey, Hannah Marie. "The Use of Bananas in Preventing Exercise Associated Muscle Cramps." Thesis, North Dakota State University, 2014. https://hdl.handle.net/10365/27535.

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Bananas have been consumed by athletes in the belief that they prevent muscle cramping. However, there are no studies in the literature that test plasma potassium concentration as a prevention technique for exercise associated muscle cramps. The purpose of this study was to determine if potassium in bananas increased threshold frequency (TF) of an electrically induced muscle cramp (EIMC) in young adults who have a history of muscle cramps. On the day of testing, subjects had a baseline blood sample and baseline EIMC, then ate 2 servings (300g) of bananas. After 60 minutes of rest, a final blood sample was drawn and a final EIMC was induced. Plasma potassium concentration did significantly increase, whereas cramp TF did not. Potassium in bananas does not affect cramp TF one hour after ingestion.

22

Hedin, Andreas. "CRAMO : Continuously Rendered Aerial Maps with Open Data." Thesis, Linnéuniversitetet, Institutionen för datavetenskap och medieteknik (DM), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-85290.

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One issue with a lot of the free aerial satellite maps that exists is the actuality of the acquired images in terms of the acquisition date. A lot of times the images are a few years old and will not represent the current reality. This project will try and mitigate this by using free open data from the Copernicus directive supplied by the European Space Agency ESA and use that to create maps. By doing this the ability to have daily updated aerial satellite maps occurs and that could be really interesting for scientific and commercial purposes. To make this work an automated process was created that downloaded the images from Copernicus and processed them with GDAL to create the maps. The process deals with the issues of mosaicing, reprojection and unattended downloads amongst other things. In the results, there is a comparison between three different maps to give a comparison and an idea of how big of a map the process can handle in a reasonable time.

23

Schmidt, Lukas [Verfasser], Marc Oliver [Gutachter] Bettzüge, and Peter [Gutachter] Cramton. "On Market Designs for Emission Reduction - Interplay of Carbon and Power Markets / Lukas Schmidt ; Gutachter: Marc Oliver Bettzüge, Peter Cramton." Köln : Universitäts- und Stadtbibliothek Köln, 2021. http://d-nb.info/1236341171/34.

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CHIBA, Bruce Fabini Franco. "Verificação experimental do modelo efetivo de Hudson-Crampin para meios anisotrópicos fissurados cujo o meio de fundo apresenta isotropia transversal." reponame:Repositório Institucional da CPRM, 2017. http://rigeo.cprm.gov.br/xmlui/handle/doc/17851.

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Submitted by Teresa Cristina Rosenhayme (teresa.rosenhayme@cprm.gov.br) on 2017-07-13T17:27:58Z No. of bitstreams: 1 Dissertação de BRUCE F. F. CHIBA.pdf: 3620420 bytes, checksum: 6d15ebae53bb30f9fc3b7afecd429c86 (MD5)
Approved for entry into archive by Flasleandro Oliveira (flasleandro.oliveira@cprm.gov.br) on 2017-07-14T09:57:27Z (GMT) No. of bitstreams: 1 Dissertação de BRUCE F. F. CHIBA.pdf: 3620420 bytes, checksum: 6d15ebae53bb30f9fc3b7afecd429c86 (MD5)
Made available in DSpace on 2017-07-14T09:57:27Z (GMT). No. of bitstreams: 1 Dissertação de BRUCE F. F. CHIBA.pdf: 3620420 bytes, checksum: 6d15ebae53bb30f9fc3b7afecd429c86 (MD5) Previous issue date: 2017-03

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Pelka, Niels [Verfasser], Oliver [Akademischer Betreuer] Mußhoff, Stephan von [Akademischer Betreuer] Cramon-Taubadel, and Ludwig [Akademischer Betreuer] Theuvsen. "Wetterrisiken in der landwirtschaftlichen Produktion / Niels Pelka. Gutachter: Oliver Mußhoff ; Stephan Von Cramon-Taubadel ; Ludwig Theuvsen. Betreuer: Oliver Mußhoff." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://d-nb.info/1067626433/34.

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Pelka, Niels Verfasser], Oliver [Akademischer Betreuer] Mußhoff, Stephan von [Akademischer Betreuer] Cramon-Taubadel, and Ludwig [Akademischer Betreuer] [Theuvsen. "Wetterrisiken in der landwirtschaftlichen Produktion / Niels Pelka. Gutachter: Oliver Mußhoff ; Stephan Von Cramon-Taubadel ; Ludwig Theuvsen. Betreuer: Oliver Mußhoff." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://nbn-resolving.de/urn:nbn:de:gbv:7-11858/00-1735-0000-0022-5DBB-4-9.

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27

Fliessbach, Astrid [Verfasser], Stephan von [Akademischer Betreuer] Cramon-Taubadel, Rico [Gutachter] Ihle, and Bernhard [Gutachter] Brümmer. "Price cycles and synchronization in South America / Astrid Fliessbach ; Gutachter: Rico, Ihle; Bernhard, Brümmer ; Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2020. http://d-nb.info/1205544747/34.

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Müller, Martin Verfasser], Jörg [Akademischer Betreuer] [Kröger, Stefan [Gutachter] Krischok, and Simon [Gutachter] Crampin. "Single-atom junctions and novel electron confinement mechanism on Pb(111) / Martin Müller ; Gutachter: Stefan Krischok, Simon Crampin ; Betreuer: Jörg Kröger." Ilmenau : TU Ilmenau, 2017. http://d-nb.info/117814156X/34.

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Müller, Martin [Verfasser], Jörg [Akademischer Betreuer] Kröger, Stefan [Gutachter] Krischok, and Simon [Gutachter] Crampin. "Single-atom junctions and novel electron confinement mechanism on Pb(111) / Martin Müller ; Gutachter: Stefan Krischok, Simon Crampin ; Betreuer: Jörg Kröger." Ilmenau : TU Ilmenau, 2017. http://d-nb.info/117814156X/34.

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30

Murase, Nagako. "Abnormal premovement gating of somatosensory input in writer's cramp." Kyoto University, 2001. http://hdl.handle.net/2433/151458.

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31

Pegoraro, Roger V. "Electrical train stimulation to assess exercise associated muscle cramp." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2010. https://ro.ecu.edu.au/theses/1845.

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Muscle cramp is a forceful, involuntary contraction of skeletal muscle, but its underlying mechanisms are not well understood. Our limited understanding of muscle cramp may be due to its unreliable occurrence. Electrical train stimulation (ETS) has been reported to induce cramp in the small flexor muscles of the foot, and a relationship exists between the threshold frequency (TF) of ETS to induce cramp and muscle cramp susceptibility. The use of ETS to induce muscle cramp in the calf muscles however may be challenging, and the test-retest reliability of this method has not been examined in the calf muscles. Since athletes can experience muscle cramp in the calf muscles, in turn affecting their athletic performance, it is necessary to establish a method to assess calf muscle cramp. The first purpose of this study therefore was to determine the usefulness of the ETS application to the calf muscles, along with its reliability. Using a Compex 2 stimulator, ETS was applied to the calf muscles of both dominant and non-dominant legs in 10 men (33.5 ± 8.4 y) who reported experiencing cramp during training or competition. Each leg was treated separately in a counterbalanced order, with subjects in the supine position and legs supported by a bench that fixed the ankle at maximal plantarflexion. ETS consisted of 2 s (including 500 ms ramp time) of 300 μs square pulsed waves followed by 30 s rest. ETS commenced with two bouts of stimulation at 10 Hz during which the stimulation intensity was increased to the maximum tolerated, with values of 46.9 ± 6.5 and 45.4 ± 7.7 mA for the dominant and non-dominant legs, respectively. Subsequent stimulation trains increased by 3 Hz until cramp occurred, as confirmed by a spontaneous electromyograph (EMG) signal. The protocol was repeated 30 min after the first test, with the entire testing procedure repeated seven days later. Muscle cramp was induced in all subjects, but the TF varied amongst subjects (13-55 Hz). Mean TF value to induce muscle camp for the dominant leg was 25.0 ± 7.6 Hz for the first test and 23.7 ± 5.0 Hz for the second test. The non-dominant leg also showed similar values. Test-retest reliability, as indicated by the intraclass correlation coefficient (ICC), limits of agreement (LOA) and coefficient of variation (CV), were 0.94, 5.4 % and 9.2 %, respectively for the dominant leg, and 0.72, 9.8 % and 15.4 %, respectively for the non-dominant leg. These results show that ETS can induce muscle cramp in the calf muscles and that the TF of ETS was a reliable measure to assess the calf muscle cramp susceptibility. The second purpose of this thesis was to examine the influence of fatigue on the TF of ETS-induced muscle cramp in the calf muscles of 10 men (35.8 ± 9.2 y) who reported experiencing cramp during sporting activity. The previously described methods were used to assess muscle cramp in the calf muscles of the subject’s dominant leg with a stimulation intensity of 49.3 ± 4.9 mA before, immediately after, and 30 min after exercise. Exercise consisted of uphill treadmill walking, standing calf raises, skipping, drop jumps and cycling to fatigue, which was completed in 82.9 ± 2.0 min at an average heart rate of 141.7 ± 6.0 bpm. An isokinetic dynamometer was used to measure plantarflexor muscle torque of the dominant leg before and immediately after exercise, and following 30 mins of passive recovery. Blood and urine samples were obtained to assess electrolyte concentrations and hydration status before and immediately after exercise. Plantarflexor muscle torque decreased significantly (p < 0.05) approximately 20 % from the baseline (42.4 ± 17.1 Nm) immediately post exercise (34.6 ± 14.9 Nm), and was still significantly lower at 30 min post-exercise (37.4 ± 15.9 Nm). Serum (4.32 ± 0.35 vs 4.66 ± 0.38 mmol/L) and urine (56.3 ± 38.6 vs 87.2 ± 40.8 mmol/L) potassium concentrations, urine osmolality (551.1 ± 306.6 vs 683.9± 236.6 mmol/L), and urine specific gravity (1.014 ± 0.008 vs 1.022 ± 0.009) changed significantly from pre to post exercise, but serum osmolality, serum sodium and urine sodium concentrations remained unchanged. No significant changes in TF were evident before (23.2 ± 6.0 Hz), immediately after (22.6 ± 5.1 Hz) and 30 min post-exercise (25.3 ± 7.4 Hz). These results suggest that neither fatigue nor mild changes in hydration status affect the TF. Nevertheless, the duration of exercise used in this study might not have been sufficient to cause the physiological changes that may occur during training or racing. As muscle cramp can reliably be assessed by ETS, future investigations should use this method to uncover potential mechanisms related to muscle cramp, such as body temperature, hydration status and electrolyte concentrations.

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Vidot, Marie Helen. "Nutrition Interventions and Chronic Liver Disease." Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/21592.

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Background The liver has an integral role in all metabolic processes Hypothesis Identification of nutritional abnormalities in patients with CLD facilitates targeted nutrition intervention to improve patient outcomes Aim To investigate specific nutritional features and interventions in patients with CLD Methods The population was adults with CLD All investigations were approved by the Sydney Local Health District Research Ethics and Governance Office Studies included: Retrospective analysis of subjective global assessment (SGA), obesity, malnutrition and muscle wasting in patients with CLD Retrospective review of continuous nasogastric feeding in malnourished individuals with CLD and refractory ascites Randomised, placebo-controlled, observer-blinded study of supplementation with Synbiotics, BCAAs in hepatic encephalopathy (HE) Retrospective review of the relationship between 25-hydroxy vitamin D and HE Systematic review of treatments for muscle cramps in CLD Randomised, placebo-controlled, double-blinded, cross-over study of taurine supplementation for cramps in patients with CLD A number of novel methodologies were utilised: Computer tomography (CT) to measure psoas, anterior and lateral abdominal muscles at the 3rd lumbar vertebra The Inhibitory Control Test (ICT) and Trail Making Test (TMT) to assess HE DASS-21 (Depression, Anxiety and Stress Score, short form) to assess negative emotional states of participants with HE Synbiotics Forte™ Taurine supplements for muscle cramps in CLD Results The liver specific SGA fails to identify muscle wasting in obese patients with CLD Continuous nasogastric feeding reduces paracentesis requirements and increases muscle mass in malnourished patients with CLD There was a significant improvement in cognition in patients taking combined synbiotics and BCAAs The prevalence of HE was significantly higher in individuals with low concentrations of 25-OH vit D independent of disease severity There was lack of evidence for physician prescribed treatments for muscle cramps in CLD 2g taurine/day reduces frequency, duration and intensity of cramps in CLD Conclusion Targeted nutritional interventions improves patient symptoms and outcomes

33

Murendo, Conrad [Verfasser], Meike [Akademischer Betreuer] Wollni, Matin [Akademischer Betreuer] Qaim, and Stephan von [Akademischer Betreuer] Cramon-Taubadel. "Mobile money adoption and household welfare in Uganda / Conrad Murendo. Betreuer: Meike Wollni. Gutachter: Matin Qaim ; Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://d-nb.info/1080361588/34.

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34

Abdul, Fatah Fazleen [Verfasser], Stephan von [Akademischer Betreuer] Cramon-Taubadel, Bernhard [Gutachter] Brümmer, and Reimund [Gutachter] Roetter. "Competitiveness and Efficiency of Rice Production in Malaysia / Fazleen Abdul Fatah ; Gutachter: Bernhard Brümmer, Reimund Roetter ; Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2017. http://d-nb.info/1126724726/34.

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35

Cimatti, Zoé. "Caractérisation des oscillations hautes fréquences en magnétoencéphalographie : application à la crampe de l'écrivain." Paris 6, 2007. http://www.theses.fr/2007PA066317.

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Le rôle fonctionnel des oscillations hautes fréquence est largement inconnu, mais il semble qu'elles aient une fonction dans le traitement de l'information sensorielle. Nous proposons deux approches permettant une meilleure compréhension de ces oscillations : (1) une approche clinique, avec des patients atteints de crampe de l'écrivain, (2) un protocole d'apprentissage sensorimoteur. En utilisant une méthode d'analyse temps-fréquence, nous avons caractériser les HFO chez le sujet sains. Nous avons montré que les patients présentaient des HFO diminuées et une perte du profil asymétrique physiologique en relation avec la manualité. Ainsi, les HFO seraient en relation avec des désordres sensoriels, et pourraient être impliquées dans des pathologies comme la dystonie. Par ailleurs, les HFO semblent fortement impliquées dans le traitement de l'information somatosensorielle, et leur modulation reflèterait la mise en place de phénomènes de plasticité au cours de l'apprentissage sensorimoteur.

36

Braulick, Kyle William. "The Effect of 5% Hypohydration on Muscle Cramp Threshold Frequency." Thesis, North Dakota State University, 2012. https://hdl.handle.net/10365/26557.

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Many clinicians believe exercise associated muscle cramps (EAMC) occur because of dehydration and electrolyte losses. Experimental research supporting this theory is lacking. Mild hypohydration (3% body mass loss) does not alter cramp threshold frequency (TF), a measure of cramp susceptibility, when fatigue and exercise intensity are controlled. No experimental research has examined TF following significant (3-5% body mass loss) or serious hypohydration (>5% body mass loss). TF and blood variables of ten subjects were measured pre-post exercise. Subjects exercised in an environmental heat chamber alternating between upper arm ergometry and non-dominant leg cycling every 15 minutes until they lost 5% of their body mass or were too exhausted to continue. Significant (n=5) or serious hypohydration (n=5) did not alter cramp TF, cramp intensity, or cramp EMG amplitude. Significant and serious hypohydration with moderate electrolyte losses does not alter cramp susceptibility when fatigue and exercise intensity are controlled.

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Pagel, Max Marvin. "The Effects of Caffeine Ingestion on Muscle Cramp Threshold Frequency." Thesis, North Dakota State University, 2014. https://hdl.handle.net/10365/27359.

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Context: The effects of caffeine on muscle cramp threshold frequency were investigated. Objective: To determine the effect of caffeine on muscle cramp threshold frequency. Design: Randomized Trial. Experimental Design Setting: Institutional Research Laboratory. Participants: 11 males, 6 females. Intervention: Each subject ingested different caffeine doses over three testing days. Main Outcome Measures: Muscle cramp threshold frequency, hemoglobin, hematocrit, plasma sodium concentration, plasma potassium concentration, plasma chloride concentration, and osmolality were recorded. Results: There was a significant difference between baseline and post ingestion threshold frequency as well as significant differences between 0 mg to 500 mg and 250 mg to 500 mg. Hemoglobin, plasma potassium concentration, and osmolality were significantly different from pre to post ingestion. Conclusions: There was a significant difference from pre to post muscle cramp threshold frequency. Hemoglobin, plasma potassium concentration, and osmolality were significantly different pre to post ingestion. The significance of these findings requires further study.

38

Simon, Etienne. "Etude des récepteurs dopaminergiques dans l'inhibition des crampes abdominales induites par la phenylbenzoquinone chez la souris." Rouen, 1986. http://www.theses.fr/1986ROUE0049.

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39

Saucedo, Lucio Alberto [Verfasser], Bernhard [Akademischer Betreuer] Brümmer, Olaf [Gutachter] Korn, and Stephan von [Gutachter] Cramon-Taubadel. "Volatile agricultural markets, how much is oil to blame? / Lucio Alberto Saucedo. Betreuer: Bernhard Brümmer. Gutachter: Olaf Korn ; Stephan Von Cramon-taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2016. http://d-nb.info/1105760170/34.

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ACOSTA, ALEJANDRO [Verfasser], Stephan von [Akademischer Betreuer] Cramon-Taubadel, Rico [Gutachter] Ihle, and Alberto [Gutachter] Valdés. "Combining Industrial Organization and Econometric Methods in Price Transmission Analysis / Alejandro Acosta ; Gutachter: Rico Ihle, Alberto Valdés ; Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2017. http://d-nb.info/112571297X/34.

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41

Ebata, Ayako [Verfasser], Stephan von [Akademischer Betreuer] Cramon-Taubadel, Bernhard [Akademischer Betreuer] Brümmer, and Meike [Akademischer Betreuer] Wollni. "Policy Interventions and Smallholder Market Linkage: Case Study from Nicaragua / Ayako Ebata. Gutachter: Bernhard Brümmer ; Meike Wollni. Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://d-nb.info/1075642388/34.

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Brenes, Muñoz Thelma [Verfasser], Stephan von [Akademischer Betreuer] Cramon-Taubadel, Bernhard [Akademischer Betreuer] Brümmer, and Stephan [Akademischer Betreuer] Klasen. "Empirical investigations into performance and dynamics of agricultural firms / Thelma Brenes Muñoz. Gutachter: Bernhard Brümmer ; Stephan Klasen. Betreuer: Stephan von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://d-nb.info/1072820420/34.

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März, Alexander [Verfasser], Oliver [Akademischer Betreuer] [Gutachter] Mußhoff, Stephan von [Gutachter] Cramon-Taubadel, and Martin [Gutachter] Odening. "Applications of modern regression techniques in empirical economics / Alexander März. Betreuer: Oliver Mußhoff. Gutachter: Oliver Mußhoff ; Stephan Von Cramon-Taubadel ; Martin Odening." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2016. http://d-nb.info/1109046529/34.

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März, Alexander Verfasser], Oliver [Akademischer Betreuer] [Gutachter] Mußhoff, Stephan von [Gutachter] [Cramon-Taubadel, and Martin [Gutachter] Odening. "Applications of modern regression techniques in empirical economics / Alexander März. Betreuer: Oliver Mußhoff. Gutachter: Oliver Mußhoff ; Stephan Von Cramon-Taubadel ; Martin Odening." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2016. http://nbn-resolving.de/urn:nbn:de:gbv:7-11858/00-1735-0000-0028-87DE-4-2.

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45

Saucedo, Lucio Alberto Verfasser], Bernhard [Akademischer Betreuer] [Brümmer, Olaf [Gutachter] Korn, and Stephan von [Gutachter] Cramon-Taubadel. "Volatile agricultural markets, how much is oil to blame? / Lucio Alberto Saucedo. Betreuer: Bernhard Brümmer. Gutachter: Olaf Korn ; Stephan Von Cramon-taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2016. http://d-nb.info/1105760170/34.

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Guzman, Moya Rodney Ramiro, Robles Alejandra Liendo, Rodríguez Ammy Kiersthen Pariasca, Villegas Reyna Luz Rengifo, and Bobadilla Paola Julissa Zea. "Proyecto de parche para cólicos menstruales: HERPATCH." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/651756.

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El presente proyecto de un parche hecho con fibras naturales y aceites esenciales de eucalipto, mentol y uña de gato muestra su viabilidad en base a una investigación hecha a mujeres limeñas de los niveles socioeconómicos A y B. De esta manera, el análisis permitió identificar un grupo de mujeres que sufren de cólicos menstruales intensos y a quienes las pastillas, y demás métodos usuales para combatirlos, no les funcionan. Asimismo, se identificó que habría disponibilidad a cambiar los medicamentos tradicionales por un producto natural que sea de fácil uso y que les permita realizar sus actividades cotidianas sin problema. Por último, se vio que el público objetivo identificado prefiere ahorrar tiempo al momento de adquirir los medicamentos o cualquier otro método que use para combatir los cólicos, por lo que mostraron interés en comprarlo y recibirlo en su casa directamente. Para poner en marcha el proyecto, se procedió a hacer una investigación de mercado, industria, consumidor, competidores, así como de proveedores. Adicionalmente, se elaboraron planes estratégicos para desarrollar el proyecto: Plan Estratégico, Plan de Marketing, Plan de Operaciones, Plan de Recursos Humanos, Plan Financiero y Plan de Responsabilidad Social, los cuales contienen estrategias y objetivos concisos para poder encaminar el proyecto. Como resultado de lo descrito anteriormente, con una inversión inicial de S/. 49,149, se obtendrán utilidades netas de S/. 39,990 para el primer año, S/. 129,811 para el segundo y S/. 304,186 para el tercero.
The present project of a patch made of natural fibers and three essential oils: eucalyptus, menthol and cat’s claw, shows its viability based on our research on women who live in Lima and belong to socioeconomic status A and B. In this way, the analysis allowed us to identify a group of women who suffer from intense menstrual cramps and whom pills and other traditional methods don’t help to ease the pain. Likewise, we identified that women are willing to change usual medicine to an easy-to-use product which allows them to continue doing their daily activities. Finally, we noticed the target segment prefers to save time when buying their usual medicine or any other method they use to ease menstrual cramps. That is why they showed interest in buying our product online and getting it delivered to their houses. To begin with the project, we carried out a market research, industry, consumer, competitors and suppliers research. Additionally, we elaborated strategic plans to develop our project: Strategic Plan, Marketing Plan, Operations Plan, Human Resources Plan, Finances Plan and Social Responsibility Plan, which contain precise strategies and objectives to lead the project. As a result of what’s been described previously, investing S/. 49,149, we will get net profits of S/. 39,990 for the first year, S/. 129,811 for the second year, and S/. 304,186 for the third year.
Trabajo de investigación

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Kurniawan, Dede Indra. "Statin-induced myopathy and the benefit of oral administration of coenzyme Q10." Thesis, Curtin University, 2007. http://hdl.handle.net/20.500.11937/1014.

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Background. Muscle cramps are one of the adverse affects suffered by hypercholesterolemia patients who are treated with statins. Besides reducing cholesterol levels, statins also reduce coenzyme Q10 (CoQ10) blood levels. One of several hypotheses of pathophysiology for statin-induced muscle cramps is reduced level of CoQ10. Besides being a very important antioxidant, CoQ10 also functions as a transmembrane proton conductor and an electron carrier between NADH and succinate dehydrogenases and the cytochrome system, which is needed for phosphorylation of ADP into ATP. Therefore, a decrease in the CoQ10 tissue levels, as reflected in its reduced blood levels, may contribute to the muscle function impairment. Researchers have proven that statins, drugs used to lower cholesterol, are able to reduce CoQ10 blood levels.Null Hypothesis. The administration of CoQ10 will have no effect on the frequency, severity and/or duration of muscle cramps amongst statin users.Aims. This study aimed to assess factors that might influence the development of statininduced myopathy manifested as muscle cramps, including the respondent’s age and sex; the dose and duration of their statin therapy; muscle symptoms (nature, duration and whether or not they have changed with statin use); other medicines consumed; and, other diseases suffered and to investigate the efficacy of oral CoQ10 supplements in reducing muscle cramps in statin users and non-users.Methods. The Study was comprised of two phases: Phase 1 the Muscle Adverse Effect Survey and Phase 2 the Coenzyme Q10 for Muscle Cramps Study. Data collection for Phase 1 took place from January 2006 to April 2006 in 45 community pharmacies throughout Western Australia. The second phase of the study, the clinical trial, took place through School of Pharmacy, Curtin University of Technology, from May 2006 to December 2006.Results. In the first phase of the study, the Muscle Adverse Effect Survey, it was found that the prevalence of myopathy amongst statin users was 22.3% (205/920). Amongst the respondents with muscle symptoms, 73/205 (35.6%) reported their muscle symptoms had worsened on using statins. Assuming non-respondents did not suffer from muscle problems reduced the overall incidence of potential statin-induced myopathy to 73/920 or 7.93%. It was found that atorvastatin was the most commonly prescribed statin (59.3%), followed by simvastatin (29.8%), then pravastatin (10.4%) and fluvastatin (0.6%). Despite the high use of atorvastatin, the incidence rate of myopathy by atorvastatin users was found to be similar with other statins. The most common muscle symptoms were night cramps (54.6%), muscle aching (52.7%), and fatigue (49.3%), while the most commonly affected area of the body was the calves (62%).Statistical analysis with multiple logistic regression showed increasing age, heart failure and the use of cortisone-like drugs increased the risk of muscle symptoms among statin users. It was found that, for every 1-year increase in age, the odds of suffering from muscle symptoms increased 1.039 (95% CI 1.019 – 1.061). Furthermore, taking cortisone-like medication increased the odds of suffering muscle symptoms 16.4 times (95% CI; 2.2 – 124.3), while participants with heart failure were 9.3 times (95% CI 1.2 – 73.2) more likely to develop muscle symptoms when prescribed statins.The second phase of the study, the Coenzyme Q10 for Muscle Cramps Study, was a single blind, placebo-controlled, cross over, 6-week evaluation of the benefits CoQ10 in reducing muscle cramps amongst statin users and non-users. It was found that on average, that statin users experienced a significant reduction in the severity of their muscle cramps, as indicated by lower average pain scores, during the period they were on CoQ10 (6.36 ± 0.75) compared with placebo (7.37 ± 0.85; p = 0.028). Furthermore, patients also experienced significantly shorter cramp duration when they were on CoQ10 (4.88 ± 0.84) than on placebo (5.84 ± 0.84; p = 0.001). In contrast, amongst non-statin users (who were used as controls), there were no significant differences between CoQ10 and placebo efficacy in all assessed variables.Conclusion. This study revealed that muscle symptoms were common among statin users, particularly those suffering from heart failure, taking corticosteroids, and increasing age. Furthermore, the administration of CoQ10 100 mg per day was safe and effective in reducing severity and duration of muscle cramps amongst statin users. However, these later findings need to be confirmed by larger, double blind, placebo controlled studies.

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Ullah, Sami [Verfasser], Bernhard [Akademischer Betreuer] Brümmer, Matin [Gutachter] Qaim, and Stephan von [Gutachter] Cramon-Taubadel. "Efficiency Measurement of Dairy Farmers under Integrated Cropping Sytems in Pakistan / Sami Ullah. Betreuer: Bernhard Brümmer. Gutachter: Matin Qaim ; Stephan Von Cramon-Taubadel." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2016. http://d-nb.info/1110148267/34.

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Prehn, Sören [Verfasser], Bernhard [Akademischer Betreuer] Brümmer, and Stephan von [Akademischer Betreuer] Cramon-Taubadel. "Agriculture & New New Trade Theory : Theoretical, Methodological, and Empirical Issues / Sören Prehn. Gutachter: Bernhard Brümmer ; Stephan von Cramon-Taubadel. Betreuer: Bernhard Brümmer." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://d-nb.info/1044414103/34.

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Beber, Caetano Luiz [Verfasser], Ludwig [Akademischer Betreuer] Theuvsen, Stephan von [Gutachter] Cramon-Taubadel, and Achim [Gutachter] Spiller. "The Dairy Supply Chain in Southern Brazil: Structure – Efficiency – Competitiveness / Caetano Luiz Beber ; Gutachter: Stephan von Cramon-Taubadel, Achim Spiller ; Betreuer: Ludwig Theuvsen." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2019. http://d-nb.info/1184573301/34.

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