Книги з теми "Cover sequence"
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1
Artmann, Hans Carl. Under the cover of a hat ; Green-sealed Message: Montages and sequences ; 90 dreams [respectively]. London: Quartet Books, 1985.
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2
Gribskov, Michael, and John Devereux, eds. Sequence Analysis Primer. Oxford University Press, 1995. http://dx.doi.org/10.1093/oso/9780195098747.001.0001.
Повний текст джерелаАнотація:
Computerized sequence analysis is an integral part of biotechnological research, yet many biologists have received no formal training in this important technology. Sequence Analysis Primer offers the beginner the necessary background to enter this vital field and helps more seasoned researchers to fine-tune their approach. It covers basic data manipulation such as homology searches, stem-loop identification, and protein secondary structure prediction, and is compatible with most sequence analysis programs. A detailed example giving steps for characterizing a new gene sequence provides users with hands-on experience when combined with their current software. The book will be invaluable to researchers and students in molecular biology, genetics, biochemistry, microbiology, and biotechnology.
3
Under the Cover of a Hat: Montages and Sequences and Green-Sealed Message : 90 Dreams. Salem House Publishers, 1986.
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4
Keane, Adrian, and Paul McKeown. The Modern Law of Evidence. Oxford University Press, 2020. http://dx.doi.org/10.1093/he/9780198848486.001.0001.
Повний текст джерелаАнотація:
The Modern Law of Evidence is a comprehensive analysis of the law of criminal and civil evidence and the theory behind the law. It identifies all the key issues, emphasizes recent developments and insights from the academic literature, and makes suggestions for further reading. The work begins with a definition of evidence and the law of evidence and an outline of its development to date. It then describes and analyses the key concepts, such as the facts open to proof, the forms that evidence can take, relevance, admissibility, weight, and discretion. It then proceeds to cover in a logical sequence all aspects of the subject: the burden and standard of proof, proof of facts without evidence, witnesses, examination-in-chief, cross-examination and re-examination, corroboration and care warnings, visual and voice identification, documentary and real evidence, evidence obtained by illegal or unfair means, hearsay, confessions, adverse inferences from an accused’s silence, evidence of good and bad character, opinion evidence, public policy, privilege and judgments as evidence of facts on which they were based.
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Keane, Adrian, and Paul McKeown. The Modern Law of Evidence. 14th ed. Oxford University Press, 2022. http://dx.doi.org/10.1093/he/9780192855930.001.0001.
Повний текст джерелаАнотація:
The Modern Law of Evidence is a comprehensive analysis of the law of criminal and civil evidence and the theory behind the law. It identifies all the key issues, emphasizes recent developments and insights from the academic literature, and makes suggestions for further reading. The work begins with a definition of evidence and the law of evidence and an outline of its development to date. It then describes and analyses the key concepts, such as the facts open to proof, the forms that evidence can take, relevance, admissibility, weight, and discretion. It then proceeds to cover in a logical sequence all aspects of the subject: the burden and standard of proof, proof of facts without evidence, documentary and real evidence, witnesses, examination-in-chief, cross-examination and re-examination, corroboration and care warnings, visual and voice identification, evidence obtained by illegal or unfair means, hearsay, confessions, adverse inferences from an accused’s silence, evidence of good and bad character, opinion evidence, public policy, privilege, and the admissibility of previous verdicts.
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Keane, Adrian, and Paul McKeown. The Modern Law of Evidence. Oxford University Press, 2018. http://dx.doi.org/10.1093/he/9780198811855.001.0001.
Повний текст джерелаАнотація:
The Modern Law of Evidence is a comprehensive analysis of the law of criminal and civil evidence and the theory behind the law. It identifies all the key issues, emphasizes recent developments and insights from the academic literature, and makes suggestions for further reading. The work begins with a definition of evidence and the law of evidence and an outline of its development to date. It then describes and analyses the key concepts, such as the facts open to proof, the forms that evidence can take, relevance, admissibility, weight and discretion, including the discretion to exclude evidence obtained by illegal or unfair means. It then proceeds to cover in a logical sequence all aspects of the subject: the burden and standard of proof, witnesses, examination-in-chief, cross-examination and re-examination, corroboration and care warnings, documentary and real evidence, identification evidence, hearsay, confessions, adverse inferences from an accused’s silence, evidence of good and bad character, opinion evidence, public policy, privilege, judgments as evidence of facts on which they were based, and the proof of facts without evidence.
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Lennon, Rachel, and Neil Turner. The molecular basis of glomerular basement membrane disorders. Edited by Neil Turner. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0320_update_001.
Повний текст джерелаАнотація:
The glomerular basement membrane (GBM) is a condensed network of extracellular matrix molecules which provides a scaffold and niche to support the function of the overlying glomerular cells. Within the glomerulus, the GBM separates the fenestrated endothelial cells, which line capillary walls from the epithelial cells or podocytes, which cover the outer aspect of the capillaries. In common with basement membranes throughout the body, the GBM contains core components including collagen IV, laminins, nidogens, and heparan sulphate proteoglycans. However, specific isoforms of these proteins are required to maintain the integrity of the glomerular filtration barrier.Across the spectrum of glomerular disease there is alteration in glomerular extracellular matrix (ECM) and a number of histological patterns are recognized. The GBM can be thickened, expanded, split, and irregular; the mesangial matrix may be expanded and glomerulosclerosis represents a widespread accumulation of ECM proteins associated with loss of glomerular function. Whilst histological patterns may follow a sequence or provide diagnostic clues, there remains limited understanding about the mechanisms of ECM regulation and how this tight control is lost in glomerular disease. Monogenic disorders of the GBM including Alport and Pierson syndromes have highlighted the importance of both collagen IV and laminin isoforms and these observations provide important insights into mechanisms of glomerular disease.
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Zook, Julie, and Kerstin Sailer, eds. The Covert Life of Hospital Architecture. UCL Press, 2022. http://dx.doi.org/10.14324/111.9781800080881.
Повний текст джерелаАнотація:
The Covert Life of Hospital Architecture addresses hospital architecture as a set of interlocked, overlapping spatial and social conditions. It identifies ways that planned-for and latent functions of hospital spaces work jointly to produce desired outcomes such as greater patient safety, increased scope for care provider communication and more intelligible corridors. By advancing space syntax theory and methods, the volume brings together emerging research on hospital environments. Opening with a description of hospital architecture that emphasizes everyday relations, the sequence of chapters takes an unusually comprehensive view that pairs spaces and occupants in hospitals: the patient room and its intervisibility with adjacent spaces, care teams and on-ward support for their work and the intelligibility of public circulation spaces for visitors. The final chapter moves outside the hospital to describe the current healthcare crisis of the global pandemic as it reveals how healthcare institutions must evolve to be adaptable in entirely new ways. Reflective essays by practicing designers follow each chapter, bringing perspectives from professional practice into the discussion. The Covert Life of Hospital Architecture makes the case that latent dimensions of space as experienced have a surprisingly strong link to measurable outcomes, providing new insights into how to better design hospitals through principles that have been tested empirically. It will become a reference for healthcare planners, designers, architects and administrators, as well as for readers from sociology, psychology and other areas of the social sciences.
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Bronner, Yigal, and Lawrence McCrea. First Words, Last Words. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780197583470.001.0001.
Повний текст джерелаАнотація:
First Words, Last Words charts an intense “pamphlet war” that took place in sixteenth-century South India. The book explores this controversy as a case study in the dynamics of innovation in early modern India, a time of great intellectual innovation. This debate took place within the traditional discourses of Vedic hermeneutics, or Mīmāṃsā, and its increasingly influential sibling discipline of Vedānta, and its proponents among the leading intellectuals and public figures of the period. At the heart of this dispute lies the role of sequence in the cognitive processing of textual information, especially of a scriptural nature. Vyāsatīrtha and his grand-pupil Vijayīndratīrtha, writers belonging to the camp of Dualist Vedānta, purported to uphold the radical view of their founding father, Madhva, who believed, against a long tradition of Mīmāṃsā interpreters, that the closing portion of a scriptural passage should govern the interpretation of its opening. By contrast, the Nondualist Appayya Dīkṣita ostensibly defended this tradition’s preference for the opening. But, as the book shows, the debaters gradually converged on a profoundly novel hermeneutic-cognitive theory in which sequence played little role, if any. In fact, they knowingly broke new ground and only postured as traditionalists. First Words, Last Words explores the nature of theoretical innovation in this debate and sets it against the background of comparative examples from other major scriptural interpretive traditions. The book briefly surveys the use of sequence in Jewish, Christian, and Islamic hermeneutics and also seeks out parallel cases of covert innovation in these traditions.
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Weirich, Paul. Rational Responses to Risks. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190089412.001.0001.
Повний текст джерелаАнотація:
A philosophical account of risk, such as this book provides, states what risk is, which attitudes to it are rational, and which acts affecting risks are rational. Attention to the nature of risk reveals two types of risk, first, a chance of a bad event, and, second, an act’s risk in the sense of the volatility of its possible outcomes. The distinction is normatively significant because different general principles of rationality govern attitudes to these two types of risk. Rationality strictly regulates attitudes to the chance of a bad event and is more permissive about attitudes to an act’s risk. Principles of rationality governing attitudes to risk also justify evaluating an act according to its expected utility given that the act’s risk, if any, belongs to every possible outcome of the act. For a rational ideal agent, the expected utilities of the acts available in a decision problem explain the agent’s preferences among the acts. Maximizing expected utility is just following preferences among the acts. This view takes an act’s expected utility, not just as a feature of a representation of preferences among acts, but also as a factor in the explanation of preferences among acts. It takes account of an agent’s attitudes to an act’s risk without weakening the standard of expected-utility maximization. The view extends to evaluations of combination of acts, either simultaneous or in a sequence. Applications cover hedging, return-risk evaluation, professional advice, and government regulation.
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Hassan, Haslinda, Raja Haslinda Raja Mohd Ali, and Nurulhuda Ghazali. Audit Command Language (ACL) Analytics: A Practical Guide for Beginners. UUM Press, 2020. http://dx.doi.org/10.32890/9789672363446.
Повний текст джерелаАнотація:
Tired of performing an audit manually? This module provides a useful step-by-step approach to perform an audit using ACL. Easy to understand and follow. No such module in the market so far. This module is designed to assist users on how to use ACL as a powerful tool to audit. The module is divided into 8 Chapters. Chapter 1 introduces audit and information technology (IT) audit, audit assertions, audit procedures, and the relationship between audit assertions and audit procedures. Chapter 2 explains ACL in the audit, describing in brief its advantages and disadvantages. Chapter 3 assists users with using ACL. In this chapter, users will learn how to install ACL (version 9), and get familiar with the ACL menus and user interfaces. This module uses a step-by-step approach to guide users from creating a new project from ACL to viewing and modifying the table in ACL. Chapter 4 elaborates how to use ACL commands for data integrity verification. For this purpose, users will learn how to count records, total numeric fields or expression, and check for validity errors. Chapter 5 shows users how to analyse their data using the ACL command. The analyse include statistics, stratify, classify, examine the sequence, check for gaps, check for duplicates, ageing, and summarise commands. The remaining chapters cover three main accounting information systems (AIS) cycles, namely, sales and cash receipts (Chapter 6), purchase and cash payments (Chapter 7), and human resource (Chapter 8). For each cycle, cases are given for better assimilation.
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Foley, John Miles. Nodes in Alphabetical Order. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252037184.003.0008.
Повний текст джерелаАнотація:
This chapter contains the core of the oral tradition/Internet technology discussions, listed in alphabetical order albeit the reader is free to create their own node-sequences as they please. The myriad topics here cover various areas of the three agoras and can range from anecdotal insights into verbal marketplaces to more comprehensive definitions of the terms and concepts used in the Pathways Project to discussions and divergences of networking among the three Agoras to reintroductions of familiar topics cast in a new light. Alongside these are further articles relating to the Pathways Project and its website proper. It must be noted, however, that, as a previous chapter has indicated, the nodes here are subject to the limitations of the tAgora, and that the website contains further and continually updated information for those who have exhausted the insights presented in this chapter.
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Turnock, Bryan. Studying Horror Cinema. Liverpool University Press, 2019. http://dx.doi.org/10.3828/liverpool/9781911325895.001.0001.
Повний текст джерелаАнотація:
Aimed at teachers and students new to the subject, this book is a comprehensive survey of the genre from silent cinema to its twenty-first century resurgence. Structured as a series of thirteen case studies of easily accessible films, it covers the historical, production, and cultural context of each film, together with detailed textual analysis of key sequences. Sitting alongside such acknowledged classics as Psycho and Rosemary's Baby are analyses of influential non-English language films as Kwaidan, Bay of Blood, and Let the Right One In. The book concludes with a chapter on 2017's blockbuster It, the most financially successful horror film of all time, making this book the most up-to-date overview of the genre available.
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Kalinin, A. A., Ye E. Savchenko, and V. Yu Prokofiev. Mineralogy and genesis of the Oleninskoe gold deposit (Kola Peninsula). FRC KSC RAS, 2021. http://dx.doi.org/10.37614/978.5.91137.446.4.
Повний текст джерелаАнотація:
Data on geology of the Oleninskoe deposit, and results of mineralogical and geochemical investigations of ores and altered rocks are presented. Mineralization is connected with granite porphyry sills, an end member of gabbrodiorite-diorite-granodiorite complex of minor intrusions. The main alteration processes are diopsidization and biotitization, formation of quartz-muscovite-albite, quartz-aresenopyrite-tourmaline, and quartz metasomatic rocks. More than 50 ore minerals (sulfides, sulfosalts, tellurides, and native metals) were identified in the ore, including 20 minerals of silver and gold. Mineral associations in the ore and sequence of mineral formation are defined. Five generations of gold-silver alloys are identified, its composition covers spectrum from native silver to high-grade gold. Mineralized fluids in the deposit are of high salinity (sodium and calcium chlorides), and rich in As, Sb, Pb, Cu, Zn, and Ag. The Oleninskoe deposit is classified as an epithermal metamorphosed gold deposit.The book is of interest for specialists in economic geology, mineralogy and geochemistry of ore deposits.
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Clarke, Andrew. Temperature and reaction rate. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780199551668.003.0007.
Повний текст джерелаАнотація:
All other things being equal, physiological reaction rate increases roughly exponentially with temperature. Organisms that have adapted over evolutionary time to live at different temperatures can have enzyme variants that exhibit similar kinetics at the temperatures to which they have adapted to operate. Within species whose distribution covers a range of temperatures, there may be differential expression of enzyme variants with different kinetics across the distribution. Enzymes adapted to different optimum temperatures differ in their amino acid sequence and thermal stability. The Gibbs energy of activation tends to be slightly lower in enzyme variants adapted to lower temperatures, but the big change is a decrease in the enthalpy of activation, with a corresponding change in the entropy of activation, both associated with a more open, flexible structure. Despite evolutionary adjustments to individual enzymes involved in intermediary metabolism (ATP regeneration), many whole-organism processes operate faster in tropical ectotherms compared with temperate or polar ectotherms. Examples include locomotion (muscle power output), ATP regeneration (mitochondrial function), nervous conduction and growth.
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Wise, Matt, and Paul Frost. Nutritional support in the critically ill. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0334.
Повний текст джерелаАнотація:
Major injury evokes a constellation of reproducible hormonal, metabolic, and haemodynamic responses which are collectively termed ‘the adaptive stress response’. The purpose of the adaptive stress response is to facilitate tissue repair and restore normal homeostasis. If critical illness is prolonged, the adaptive stress response may become maladaptive, in essence exerting a parasitic effect leaching away structural proteins and impairing host immunity. Primarily therapy should be directed towards the underlying illness, as nutritional support per se will not reverse the stress response and its sequelae. Nonetheless, adequate nutritional support in the early stages of critical illness may attenuate protein catabolism and its adverse effects. This chapter covers nutritional assessment; detection of malnutrition; energy and protein requirements; monitoring the effectiveness of nutritional replacements; nutritional delivery; complications; and refeeding syndrome.
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Sætre, Glenn-Peter, and Mark Ravinet. Evolutionary Genetics. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198830917.001.0001.
Повний текст джерелаАнотація:
Evolutionary genetics is the study of how genetic variation leads to evolutionary change. With the recent explosion in the availability of whole genome sequence data, vast quantities of genetic data are being generated at an ever-increasing pace with the result that programming has become an essential tool for researchers. Most importantly, a thorough understanding of evolutionary principles is essential for making sense of this genetic data. This up-to-date textbook covers all the major components of modern evolutionary genetics, carefully explaining fundamental processes such as mutation, natural selection, genetic drift, and speciation, together with their consequences. In addition to the text, study questions are provided to motivate the reader to think and reflect on the concepts in each chapter. Practical experience is essential when it comes to developing an understanding of how to use genetic data to analyze and address interesting questions in the life sciences and how to interpret results in meaningful ways. Throughout the book, a series of online, computer-based tutorials serves as an introduction to programming and analysis of evolutionary genetic data centered on the R programming language, which stands out as an ideal all-purpose platform to handle and analyze such data. The book and its online materials take full advantage of the authors’ own experience in working in a post-genomic revolution world, and introduce readers to the plethora of molecular and analytical methods that have only recently become available.
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Rayner, Mike, Kremlin Wickramasinghe, Julianne Williams, Karen McColl, and Shanthi Mendis, eds. An Introduction to Population-level Prevention of Non-Communicable Diseases. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198791188.001.0001.
Повний текст джерелаАнотація:
This book is based on the content covered during the non-communicable disease (NCD) prevention short course at the University of Oxford. It provides theoretical background and ‘real life case studies’ helping readers to apply the learnings to their day-to-day work. It covers case studies from both high-income countries and low- and middle-income countries. This book is structured around the four stages of the policy cycle: (1) problem definition; (2) solution generation; (3) resource mobilization and implementation; and (4) evaluation. Chapters 2–7 focus on problem definition, which involves understanding the burden of NCDs, its risk factors, the sociopolitical landscape, the role of advocacy, and screening and surveillance. Chapters 8–10 are about solution generation, which involves examining the evidence for potential costs and benefits of interventions, while also considering contextual factors, including the ethical and political dimensions of different solutions. Chapters 11–13 are on implementation and the mobilization of resources, both the money needed for material aspects of the interventions and the people required to plan for and carry out the interventions. Chapter 14 is about evaluation and monitoring, which may be designed to assess whether interventions met their aims and objectives. Given the cyclical nature of the policy cycle, the final chapter is about returning to the various stages. NCD prevention does not always follow the stages of the policy cycle in a strict sequence and often, NCD interventions will need revisiting in light of the experiences and lessons learned from earlier stages.
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Elliott, Doug, and Linda Denehy. Post-ICU Rehabilitation. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199653461.003.0051.
Повний текст джерелаАнотація:
More than three-quarters of patients who experience a critical illness and intensive care unit admission survive their initial physiological insult and are subsequently discharged from hospital. Some of these survivors have physical, psychological, or cognitive deficits that persist and delay optimal recovery in the following months and, in some instances, years. A range of generic screening and functional assessment strategies has been used with post-ICU cohorts, but methodological limitations were evident. Further research is therefore required, possibly using a battery of instruments to cover a broad range of function across the recovery period, to explore optimal screening times. Commencing or continuing rehabilitation strategies for patients after ICU discharge in both hospital and post-hospital environments have their own set of challenges. A key step is to improve awareness and understanding of the sequelae of critical illness among rehabilitation specialists, primary care practitioners, and the broader health community. Coordination and optimal use of scarce resources in hospital and community settings is required. Evidence supporting post-ICU rehabilitation interventions is mixed. Studies are needed to discern which patients likely to respond and the optimal amount, type, and timing of interventions. Innovative use of wearable technologies and smartphone or tablet applications may offer some solutions for monitoring, motivation, compliance, and optimal recovery for survivors of a critical illness who have identified functional deficits.
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Bakhtiar, Syeda Marriam, and Erum Dilshad, eds. Omics Technologies for Clinical Diagnosis and Gene Therapy: Medical Applications in Human Genetics. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/97898150795171220101.
Повний текст джерелаАнотація:
Genetic disorders have been the focus of scientists for a long time. The emergence of next-generation sequencing techniques has ushered a new era in genetics and several developments have occurred in human genetics. The scientific perspective has also been widened with omics technologies that allow researchers to analyze genetic sequences and their expression products. An integrated approach is being used not only for diagnosis but also for disease management and therapeutic purposes. This book highlights emerging areas of omics technology and its application in the diagnosis and management of human genetic disorders. The book covers three areas of research and implementation: 1) Diagnosis (covering conventional strategies to next-generation platforms). This section focuses on the role of in silico analysis, databases and multi-omics of single-cell which will help in designing better management strategies. 2) Disease Management and therapeutic interventions. This section starts with genetic counselling and progresses to more specific techniques such as pharmacogenomics and personalized medicine, gene editing techniques and their applications in gene therapies and regenerative medicine. 3) Case studies. This section discusses the applications and success of all the above-mentioned strategies on selected human disorders. This book serves as a handy reference for students and academics studying advanced omics techniques in biochemistry and molecular genetics as part of courses in life sciences, pharmacology and medicine.