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1

Gowd, Anirudh K., Timothy Luchetti, Jacob Birlingmair, Nikhil N. Verma, Anthony A. Romeo, and Antonia Zaferiou. "Role of the Long Head of the Biceps During Active Pitching in Healthy Collegiate Athletes: An Electromyographic Evaluation." Orthopaedic Journal of Sports Medicine 7, no. 7_suppl5 (July 2019): 2325967119S0043. http://dx.doi.org/10.1177/2325967119s00438.

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Objectives: Supraphysiologic forces placed on the glenohumeral joint during pitching leads to a high incidence of bicipital-labral pathology in competitive pitchers. Heavy debate in operative management between biceps tenodesis, labral repair, and debridement warrants further study in the role of the biceps during pitching. The purpose of this study was to evaluate the recruitment of the long and short heads of the biceps utilizing electromyographic evaluation and correlate activity with pitch velocity. Methods: Seventeen healthy, competitive, pitchers were recruited and consented to pitch in a controlled laboratory setting, under electromyographic observation. Surface electromyography (sEMG) was performed via electrodes placed on either head of the biceps, deltoid, infraspinatus, and latissimus dorsi, band pass filtered between 10-500 Hz and sampled at a rate of 1500 Hz during the pitching motion. sEMG was normalized to maximal volumetric isometric contraction (MVIC) via manual muscle testing (MMT). Pitch velocity was measured using a Speedster III radar gun, and then correlated to sEMG readings. Results: Average age of recruited subjects was 19.8 ± 1.4 years old. Average number of years pitched was 10.3 ± 3.6 years. Fourteen players reported their highest level of play was college, while two reported semi-professional, and one reported high-school. Average pitch velocity from included pitches was 70.6 ± 4.0 (range: 61 - 79). sEMG signals were interpreted in three modalities: median signal, integral sum of all signals, and time spent (ms) above 10% MVIC. Pitch velocity did not correlate to any sEMG analysis (p>0.05) by bivariate linear regression. Coefficient of variation was greater between pitchers than within pitchers. Greater than 80% of pitchers demonstrated statistically different activation of the long head of biceps muscle (LHBM) versus short head of biceps muscle (SHBM) (Figure 1). Three players had significantly greater short head activation, while 12 players had significantly greater long head activation. Conclusion: The long and short heads of the biceps are consistently activated during pitching, suggested they have a role during the late cocking and deceleration phase of pitching, although not correlated to ball acceleration. Preferential recruitment of either long or short head biceps suggest variability in fast ball pitching styles, that warrant further research for clinical implications. [Figure: see text]
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2

Brüning, E. M., M. Baenitz, A. A. Gippius, A. M. Strydom, F. Steglich, and R. E. Walstedt. "119Sn NMR on the correlated semi-metal." Journal of Magnetism and Magnetic Materials 310, no. 2 (March 2007): 393–95. http://dx.doi.org/10.1016/j.jmmm.2006.10.100.

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3

Falsone, G., and D. Settineri. "Exact stochastic solution of beams subjected to delta-correlated loads." Structural Engineering and Mechanics 47, no. 3 (August 10, 2013): 307–29. http://dx.doi.org/10.12989/sem.2013.47.3.307.

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4

Liu, Chunhua, Ton-Lo Wang, and Dongzhou Huang. "Impact study for multi-girder bridge based on correlated road roughness." Structural Engineering and Mechanics 11, no. 3 (March 25, 2001): 259–72. http://dx.doi.org/10.12989/sem.2001.11.3.259.

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5

Han, Wanshui, Sujing Yuan, and Lin Ma. "Vibration of vehicle-bridge coupling system with measured correlated road surface roughness." Structural Engineering and Mechanics 51, no. 2 (July 25, 2014): 315–31. http://dx.doi.org/10.12989/sem.2014.51.2.315.

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6

Ben Chaouacha, H., N. Ben Nessib, and S. Sahal-Bréchot. "Semi-classical collisional functions in a strongly correlated plasma." Astronomy & Astrophysics 419, no. 2 (May 2004): 771–76. http://dx.doi.org/10.1051/0004-6361:20034093.

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7

Ben Chaouacha, H., N. Ben Nessib, and S. Sahal Bréchot. "Semi-classical collisional functions in a strongly correlated plasma." Astronomy & Astrophysics 433, no. 3 (March 29, 2005): 1153–54. http://dx.doi.org/10.1051/0004-6361:20034093e.

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8

Giacomin, M. "Does community care works? Evaluate the effectiveness of mental health services." European Psychiatry 33, S1 (March 2016): S631. http://dx.doi.org/10.1016/j.eurpsy.2016.01.2372.

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IntroductionImproving quality require the capability to evaluate clinical and operational processes and improve patients outcomes. Just in the view of evidence-based practise (EBP) it's used HONOS rating Scale, adopted since May 2012, by Mental Health Center of Villorba (Treviso-Italy) There are 3 package treatments: rehabilitative, territorial and clinical.ObjectivesTo identify which variables are positively correlated to HONOS improvement in patients group who frequented Mental Health Centre along 36 months. All patients present severe mental illness.AimsEvaluate the effectiveness of interventions and correlate to treatment package and individual feature. Analyze treatment process for quality improvement.MethodA psychiatric team (4 nurses, 1 psychiatrist) administered Honos Rating Scale along 3 years: on starting point and 6, 12 and 36 months later: T 0,1,2,3,4. Patients are also described by diagnosis, mental, social and autonomy skill, time, utilization of MHC and anagraphic information.ResultsAll 15 groups’ patients realize lower scoring, after 36 months’ treatment. Seven have got reliable improvement (i.e. = > 8-point lowering T3–T4) and positively correlate with: (1) 36 months’ treatment, at 12 months in rehabilitative Package; (2) days in residential/semi-residential community from 82 to 311 days. Related tables are included in paper.Discussion and conclusionHONOS score correlates directly with clinical and riabilitation improvement, i.e. mental, social capacity, and personal autonomy. It needs more investigation to clear which other factors are involved with improvement.Disclosure of interestThe author has not supplied his/her declaration of competing interest.
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9

Janevski, Goran, Predrag Kozic, and Ivan Pavlovic. "Moment Lyapunov exponents of the Parametrical Hill's equation under the excitation of two correlated wideband noises." Structural Engineering and Mechanics 52, no. 3 (November 10, 2014): 525–40. http://dx.doi.org/10.12989/sem.2014.52.3.525.

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10

Sobol, R. W., H. Tawbi, D. M. Jukic, K. Mule, R. Mascari, and J. M. Kirkwood. "Mismatch repair (MMR) and base excision repair (BER) protein expression correlates with clinical response to dacarbazine (DTIC)/temozolomide (TMZ) therapy of patients with metastatic melanoma." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 8015. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.8015.

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8015 Background: The non-classical alkylators DTIC and TMZ exert their cytotoxic effect through methylation of DNA bases. DNA damage is repaired by direct reversal of the O6-MeG lesion by the protein O6-methylguanine-DNA methyltransferase (MGMT/AGT); recognition of alkylation-damage-induced replication errors by the MMR pathway and excision repair of alkylated bases (N7-MeG and N3-MeA) conducted by the BER pathway. We report the results of a study evaluating the correlation between MGMT, MMR and BER protein expression in tumor tissue of patients (pts) with metastatic melanoma and documented clinical response to chemotherapy. Methods: Frozen tumor tissue was obtained from 17 pts with metastatic melanoma treated with DTIC/TMZ. Tumors were classified as sensitive (S) if pts showed stable disease (SD), partial response (PR) or complete response (CR) by RECIST criteria; and resistant (R) if progressive disease (PD) was observed after 2 cycles of treatment with DTIC/TMZ. Immunohistochemical staining for MGMT, MLH1 (MMR), and DNA polymerase-ß (pol-ß, BER) was performed. Levels of expression were assessed by a pathologist blinded to response data. Fisher’s Exact and Wilcoxon Rank Sum statistical tests were used to assess correlations. Results: 9 tumors were considered to be sensitive (S) and 7 resistant (R). Clinical response was found to significantly correlate with functional MMR (increased MLH1 expression): 7 of 9 S tumors had high MLH1 expression as compared to 1 of 7 R (p-value=0.015). Clinical response was also found to be inversely correlated with pol-ß expression: 6 of 9 S tumors expressed low levels of pol-ß as compared to 1 of 7 R tumors (p-value=0.08). MGMT expression did not seem to correlate with response. Conclusions: The presence of a functional MMR pathway is a requirement for the cytotoxic effect of alkylating agents and was significantly correlated with clinical response. Decreased BER potential (pol-ß expression) was correlated with increased sensitivity to alkylator-based chemotherapy. These findings lend additional support to the view that DNA repair status correlates with response to alkylator-based chemotherapy for melanoma. No significant financial relationships to disclose.
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11

Jiang, J. Q., and L. J. McQuay. "Predicting Protein Function by Multi-Label Correlated Semi-Supervised Learning." IEEE/ACM Transactions on Computational Biology and Bioinformatics 9, no. 4 (July 2012): 1059–69. http://dx.doi.org/10.1109/tcbb.2011.156.

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12

Castellarin, A., D. H. Burn, and A. Brath. "Homogeneity testing: How homogeneous do heterogeneous cross-correlated regions seem?" Journal of Hydrology 360, no. 1-4 (October 2008): 67–76. http://dx.doi.org/10.1016/j.jhydrol.2008.07.014.

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13

GORAN, DEMBOSKI, JANKOSKA MAJA, and MIGUEL ANGELO CARVALHO. "Seam pucker detection through presser foot displacement monitoring." Industria Textila 73, no. 02 (April 30, 2022): 145–51. http://dx.doi.org/10.35530/it.073.02.202033.

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The paper investigates the relation between seam pucker, woven fabric formability, and the presser foot displacement during stitch formation. Superimposed seams of class 1 were sewn in warp and weft direction using woven fabrics for tailored garments. The presser foot height was continuously monitored during stitch formation for different sewing machine speeds. The foot displacement during the sewing cycle was correlated with seam pucker. The obtained results showed various patterns of pressure foot displacement regarding the sewing machine speeds. It was found that at a lower machine speed there is no bouncing of the presser foot and the ratio of the height of the presser foot before and after rising and declining movement versus double thickness of the fabric (h/T1), correlates significantly with the seam pucker percentage. The fabrics having a higher h/T1 ratio showed a higher percentage of seam pucker. The obtained results suggest that online monitoring of this parameter can be a useful indication of on-seam pucker appearance, providing reliable means to obtain a quality seam.
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14

Nugent, A., J. Gallagher, J. Dolan, N. O'Higgins, and M. J. Duffy. "Assay of the c-erbB-2 Oncogene Encoded Protein by ELISA and Immunocytochemistry in Human Breast Cancer." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 31, no. 2 (March 1994): 171–73. http://dx.doi.org/10.1177/000456329403100210.

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The c-erbB-2 gene is amplified in a wide variety of different adenocarcinomas. Generally, gene amplification correlates with increased expression of the c-erbB-2 oncoprotein. Previous assays for the c-erbB-2 oncoprotein have been qualitative or semi-quantitative. In this investigation using human breast cancers, c-erbB-2 oncoprotein levels as measured by enzyme-linked immunosorbent assay (ELISA) correlated significantly with semi-quantitation by immunocytochemistry ( r = 0·843, P<0·0001, n = 97). The cut-off point for the ELISA which gave the strongest agreement with immunocytochemistry was 15 units/μg protein. It is concluded that detection of c-erbB-2 oncoprotein by ELISA is quantitative and objective.
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15

Mirkin, Michael V., Sujoy Sarkar, Xiang Wang, and Je Hyun Bae. "(Invited) SECM and Photo-SECM on TEM Grids: Toward Correlated Electrochemical/TEM Imaging of Catalysts." ECS Meeting Abstracts MA2020-01, no. 39 (May 1, 2020): 1719. http://dx.doi.org/10.1149/ma2020-01391719mtgabs.

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16

Doua, S., R. Jérôme, B. Traverse, M. Zennadi, C. Boutet, A. Hammour, N. Germain, C. Massoubre, and B. Galusca. "Links between posterior pituitary activity, psychometric profile and other endocrine abnormalities in anorexia nervosa: a multimodal evaluation." European Psychiatry 65, S1 (June 2022): S148—S149. http://dx.doi.org/10.1192/j.eurpsy.2022.399.

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Introduction Opioid system activity was found disturbed in several reward circuit areas in restrictive anorexia nervosa (AN) patients but also at the pituitary level. The role of this specific abnormality in AN physiopathology remains unknown.O Objectives We aimed to evaluate the relationship of upper mentioned AN abnormality with its classical pituitary features and eating behavior traits. Methods PET [11C] diprenorphin binding potential (BPND) were processed for each pituitary part in three groups of young women: 12 AN, 11 recovered AN patients (ANrec), and 12 Controls. Anterior pituitary hormones and neurohypophysis (NH) 12 points circadian profile including copeptin and oxytocin, psychological scores were evaluated in these subjects as well as in 13 bulimic (BN) patients. Results [11C] diprenorphin pituitary binding was found to be fully localized in NH. Only AN patients’ NH present lower [11C] diprenorphin BPND than Controls, interpreted as a higher opioid tone. Both AN and ANrec show lower copeptin/24h than in Controls but no difference in oxytocin. BN showed increased copeptin and low oxytocin. In AN patients copeptin inversely correlate with Restrained Eating while oxytocin correlate with the External Eating score. NH [11C] diprenorphin BPND correlated with leptin but not with copeptin or oxytocin. Conclusions Neurohypopysis opioid tone in anorexia nervosa seem not to impact the vasopressin or oxytocin release but still may interfere in gonadal axis regulation. Copeptin, a good indicator of hydration state, may be a good tool to detect hidden restrictive or purging behaviors. Specific correlates with AN psychologic features still suggest a physiopathological involvement. Disclosure No significant relationships.
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17

Augustine, Dominic, Roopa S. Rao, Lakshminarayana Surendra, Shankargouda Patil, Thuckanaickenpalayam Ragunathan Yoithapprabhunath, Sarah Albogami, Shaheen Shamsuddin, Sulphi Abdul Basheer, and Shan Sainudeen. "Histopathologic Feature of Hyalinization Predicts Recurrence of Conventional/Solid Multicystic Ameloblastomas." Diagnostics 12, no. 5 (April 29, 2022): 1114. http://dx.doi.org/10.3390/diagnostics12051114.

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The histologic properties of tumors seem to affect their biological behavior, and the same holds good for solid multicystic ameloblastoma (SMA), a benign, locally destructive lesion. Hyalinization is one such histological factor that has been demonstrated to correlate with the biological behavior of neoplasms. The present study aimed to analyze the correlation between the severity of hyalinization (SOH) and the recurrence potential of SMAs. The study was performed on formalin-fixed, paraffin-embedded (FFPE) diagnosed archival cases of SMA, follicular SMA (n = 35) and plexiform SMA (n = 25). The cases were evaluated for SOH and scored from 0–3, and the correlation between SOH and recurrence was analyzed for statistical significance. The clinical parameters of the lesion were analyzed for statistical correlation with recurrence. The SOH significantly correlated with the recurrence of SMA (p = 0.001). The histologic type did not influence the biological behavior of SMA. The location of SMA in the body of the mandible (p = 0.036), multilocular radiolucency (p = 0.001) and root resorption (p = 0.002) also showed strong statistical correlation with recurrence. It is evident from the present study that hyalinization strongly correlates with the biological behavior of SMA. Future studies with advanced investigations could validate the presence of hyalinization and identify the origin of the hyalinized product in SMAs.
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18

Kiy, Gevrey, Pia Lehmann, Horst K. Hahn, Paul Eling, Andreas Kastrup, and Helmut Hildebrandt. "Decreased hippocampal volume, indirectly measured, is associated with depressive symptoms and consolidation deficits in multiple sclerosis." Multiple Sclerosis Journal 17, no. 9 (May 5, 2011): 1088–97. http://dx.doi.org/10.1177/1352458511403530.

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Background: The human hippocampus plays a role in episodic memory and depression. Recently, it has been shown, using manual tracings, that the hippocampus is smaller in volume in MS patients compared with healthy controls, and that, at least for depression, hippocampal atrophy correlates with symptom severity. Methods: Because manual tracing of the hippocampus is time consuming, we used a semi-automatic procedure for temporal horn volumetry in 72 multiple sclerosis (MS) patients and 16 control subjects as an indirect measure of hippocampal volume. We analysed memory performance with the California Verbal Learning Test (using separate indices for encoding, consolidation and retrieval) and depressive mood with the Beck’s Depression Inventory (distinguishing between psychic and somatic aspects). Results: MS patients had significantly larger temporal horn volumes and volume correlated with psychic symptoms of depressive mood. Temporal horn volume was also associated with consolidation, in particular in the most impaired group. Conclusions: Temporal horn volume can be measured relatively easily and appears to correlate with two major clinical problems in MS patients: memory performance and depressive mood. The link between temporal horn volume, consolidation and depression may be hippocampal atrophy, as suggested by their adjacent neuroanatomical localization, and by the similarity in functional loss following impairment of these two structures.
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19

Ben-Sheetrit, Joseph, Mika Zurawel, Abraham Weizman, and Iris Manor. "Symptoms Versus Impairment in Adults With ADHD: Intercorrelations of the BRIEF-A, CAARS, and TOVA." Journal of Attention Disorders 23, no. 13 (December 19, 2016): 1557–66. http://dx.doi.org/10.1177/1087054716682334.

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Objective: The aim of this study is to explore the connections within and between three measures of adult ADHD: the Behavior Rating Inventory of Executive Function–Adult Version (BRIEF-A)–Self-Report, Conners’ Adult ADHD Rating Scale–Investigator-Rated (CAARS-Inv), and Test of Variables of Attention (TOVA). Method: Data of 89 adults with ADHD (ages = 18-54, 46% females) who were assessed using these measures during pretreatment visits of a randomized study of metadoxine XR were analyzed. Results: The CAARS-Inv and TOVA did not correlate. The BRIEF-A correlated extensively with both the CAARS-Inv and TOVA, primarily via its Behavioral Regulation Index (BRI). The BRIEF-A Metacognition Index correlated with the CAARS-Inv inattentive score, while the BRI correlated with the CAARS-Inv hyperactive-impulsive score. Within the CAARS and TOVA, inattention and hyperactivity-impulsivity correlated weakly. Conclusion: The measures seem to capture different aspects of adult ADHD. While the CAARS-Inv addresses mainly the domain of symptoms, and the TOVA that of impairment, the BRIEF-A captures aspects of both.
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Ferrari, Cristina, Giulia Santo, Nunzio Merenda, Alessia Branca, Paolo Mammucci, Pamela Pizzutilo, Cosmo Damiano Gadaleta, and Giuseppe Rubini. "Immune Checkpoint Inhibitors in Advanced NSCLC: [18F]FDG PET/CT as a Troubleshooter in Treatment Response." Diagnostics 11, no. 9 (September 15, 2021): 1681. http://dx.doi.org/10.3390/diagnostics11091681.

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Introduction: The aim of this study was to investigate whether [18F]FDG PET/CT-derived semi-quantitative parameters can predict immunotherapy treatment response in non-small cell lung cancer (NSCLC) patients. Secondly, immune-related adverse events (irAEs) and lymphoid cell-rich organs activation were evaluated. Materials and Methods: Twenty-eight patients who underwent [18F]FDG PET/CT scans before and at first restaging therapy with immuno-checkpoint inhibitors (ICIs) were retrospectively analyzed. PET-based semi-quantitative parameters extracted from both scans were respectively: SUVmax and SUVpeak of the target lesion, whole-body metabolic tumor volume (MTVWB), and whole-body total lesion glycolysis (TLGWB), as well as their interval changes (ΔSUVmaxTL, ΔSUVpeakTL, ΔMTVWB, ΔTLGWB). These PET-derived parameters were correlated to controlled disease (CD) assessed by RECIST 1.1. IrAEs, if present, were also described and correlated with clinical benefit (CB). SUVmax of the spleen and bone marrow at restaging scans were also correlated to CB. Results: The CD was achieved in 54% of patients. Out of 28 eligible patients, 13 (46%) experienced progressive disease (PD), 7 showed SD, 7 had PR, and only in one patient CR was achieved. ΔSUVmaxTL (p = 0.002) and ΔSUVpeakTL (p < 0.001) as well as ΔMTVWB (p < 0.001) and ΔTLGWB (p < 0.005) were significantly associated with PD vs. non-PD. IrAEs and lymphoid cell-rich organs activation did not correlate with CB. Conclusions: [18F]FDG PET/CT by using interval changes of PET-derived semi-quantitative parameters could represent a reliable tool in immunotherapy treatment response evaluation in NSCLC patients.
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Z., Rezaei Ghahroodi. "Analysis of mixed correlated semi-continuous and β-inflated Poisson responses". Communications in Statistics - Simulation and Computation 47, № 10 (6 грудня 2017): 2992–3007. http://dx.doi.org/10.1080/03610918.2017.1367804.

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Koustourakis, Gerasimos S., Anna Asimaki, and Georgia Spiliopoulou. "Cultural capital and educational expectations of native and immigrant parents of primary school students: a qualitative study." International Journal of Sociology of Education 5, no. 3 (October 25, 2016): 166–89. http://dx.doi.org/10.17583/rise.2016.1892.

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This paper uses the concept of ‘cultural capital’ from the theory of Pierre Bourdieu and it aims on the one hand to investigate the similarities and differences between the institutionalized and objectified cultural capital of native and immigrant parents of state primary school students in Greece and on the other hand to correlate these two forms of cultural capital with their expectations for the educational future of their children. The research was conducted during the spring semester of 2014 with the use of semi-structured interviews, in which 20 parents (10 native and 10 immigrant) of children in the 6th grade of primary schools in the city of Patras participated. The results of this study showed that there were more differences than similarities between these two categories of parents and they are mainly focused on cultural goods which exist in their house as well as on cultural activities of family members during their spare time. The educational expectations of the sum total of parents of students regardless of national origin and educational level seem to be very high. It also emerged that educational level and occupation of parents is correlated to their specific expectations for the educational future of their children.
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23

Le Bihan, Y., and P. Lessard. "Influence of operational variables on enzymatic tests applied to monitor the microbial biomass activity of a biofilter." Water Science and Technology 37, no. 4-5 (February 1, 1998): 199–202. http://dx.doi.org/10.2166/wst.1998.0620.

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Enzymatic assays were used to monitor the biomass of a biofilter working under different operational conditions. In backwash waters used as biomass source, many hydrolytic enzymes as well as dehydrogenase expressed in volumetric units seem to correlate with volatile suspended solids (VSS) and with the volumetric feeding mass. However, only the specific concentration of β-Glucuronidase correlates negatively with this volumetric feeding mass. The influent temperature affects simultaneously the specific concentration of β-Glucosidase, the headloss behaviour and the total sugars/VSS ratio. For the properties of the biomass, the sludge volume index (SVI) of the backwash waters correlates with Leu-aminopeptidase, suggesting that this enzyme could have been produced by filamentous organisms.
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Pöttler, Marina, Andrea Aaitel, Manuela Schmidinger, Christoph Zielinski, and Gerald Prager. "CD98hc (SLC3A2), a novel biomarker correlating with grade of malignancy in renal cell cancer." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): e15083-e15083. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e15083.

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e15083 Background: In a variety of malignant diseases certain malignant markers either predict treatment response towards systemic therapies or have a prognostic impact for cancer patients. While a variety of such actionable as well as treatable targets have been characterized, although only in certain cancers, in renal cell cancer (RCC) no prognostic markers have so far been identified. Thus, grading according to the S.A. Fuhrman grading system from 1982 is the only prognostic feature and currently widely considered for treatment assessment. Methods: Paraffin-embedded tumor tissue sections derived from clear cell RCCs were immuno-histochemically analyzed for expression of embryonic transmembrane antigen CD98hc (SLC3A2). Expression levels were semi-quantitative analyzed and results were correlated with grade of differentiation, using the widely accepted Fuhrman classification. Results: We found that grade of malignancy of ccRCCs were directly correlated with high CD98hc expression levels. Semi-quantivative analyses revealed that 0 % (0/2) of grade 1 ccRCC, 70.0 % of grade 2 ccRCC (14/20), 86.6 % of grade 3 (26/30) and 100 % of grade 4 (10/10) were CD98hc positive. (p < 0.01, Qui-Quadrat Pearson test, n = 62). In contrast, tumor stage as determined by the WHO TNM system did not correlate with CD98hc levels (p > 0.05). Conclusions: From these data, we conclude that CD98hc is expressed in RCCs, whereby the extent of expression is likely to correlate directly with grade of malignancy. In ccRCCs, CD98hc might represent a novel and reliable marker for more aggressive and less differentiated subtypes.
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Cao, Jay J., Leah D. Whigham, and Lisa Jahns. "Depletion and repletion of fruit and vegetable intake alters serum bone turnover markers: a 28-week single-arm experimental feeding intervention." British Journal of Nutrition 120, no. 5 (July 19, 2018): 500–507. http://dx.doi.org/10.1017/s0007114518001642.

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AbstractThis study was designed to evaluate the effects of elevated fruit and vegetable intake on bone turnover markers. In all, twenty-nine subjects (nine male and twenty female, with a mean age of 32·1 (sem2·5) years) participated in a 28-week single-arm experimental feeding intervention trial and consumed a prescribed low-fruit and vegetable diet for 6 weeks (depletion-1), a provided high-fruit and vegetable diet for 8 weeks (fruit: 360–560 g; vegetables: 450–705 g), another prescribed low-fruit and vegetable diet for 6 weeks (depletion-2) and then their usual diets for 8 weeks (repletion). Serum bone-related biomarkers were analysed with commercial ELISA kits. Plasma carotenoid levels decreased as a result of the depletion phase and increased with the high-fruit and vegetable diet. Compared with the baseline, depletion-1 resulted in higher serum bone resorption marker C-terminal telopeptide of type 1 collagen (CTX) and lower bone formation marker alkaline phosphatase (BAP) (CTX, 0·68 (sem0·05)v. 0·97 (sem0·08) ng/ml and BAP, 10·7 (sem0·7)v. 9·5 (sem0·8) µg/l for the baseline and the depletion-1, respectively,P<0·05). High intake of fruit and vegetables decreased serum CTX (P<0·05) to 0·60 (sem0·04) ng/ml and increased serum BAP to 11·3 (sem0·7) µg/l (P<0·05), compared with the depletion-1 phase. Serum concentrations of CTX were inversely correlated and those of BAP were positively correlated with blood lycopene. These data show that increased fruit and vegetable consumption at or above federal dietary guidance may be beneficial to bone health.
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Ishaq, Muhammad Aakif, and Filippo Giustozzi. "Correlation between Rheological Fatigue Tests on Bitumen and Various Cracking Tests on Asphalt Mixtures." Materials 14, no. 24 (December 17, 2021): 7839. http://dx.doi.org/10.3390/ma14247839.

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Accurate characterisation and appropriate binder selection are essential to increase the load-induced cracking resistance of asphalt mixtures at an intermediate temperature. Hence, the primary goal of this study was to correlate the cracking resistance exerted by the binder with the cracking performance of asphalt mixtures. The laboratory-based experimental plan covered various types of laboratory tests specified by various agencies and road authorities to study the correlation of a neat bitumen and five polymer-modified binders with their corresponding asphalt mixtures. The fatigue life of the binders was assessed through a Linear Amplitude Sweep (LAS) test and statistically correlated with various load-induced cracking parameters from the indirect tensile test, semi-circular bending (SCB) test, and four points bending beam test (FPBB) of asphalt mixtures at 25 °C. Binders and mixes were further grouped depending on their polymeric family (i.e., modified with a particular type of polymer) to validate their statistical correlation. The indicator that mostly correlated the binder properties with the asphalt mixture properties is the secant modulus from the SCB test. Fatigue parameters obtained through LAS better explain the asphalt fatigue performance obtained through FPBB; specifically, asphalt tests at high strain levels (e.g., 400 micro strain) better correlate to the LAS fatigue parameter (Nf).
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27

Takahashi, Takashi, and Yoshiyuki Kabashima. "Semi-analytic approximate stability selection for correlated data in generalized linear models." Journal of Statistical Mechanics: Theory and Experiment 2020, no. 9 (September 3, 2020): 093402. http://dx.doi.org/10.1088/1742-5468/ababff.

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28

Abukawa, T., and S. Kono. "Semi-direct method for surface structure analysis using correlated thermal diffuse scattering." Progress in Surface Science 72, no. 1-4 (June 2003): 19–51. http://dx.doi.org/10.1016/s0079-6816(03)00002-9.

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29

Ciftja, O. "Semi-Classical Model of Strongly Correlated Coulomb Systems in Weak Magnetic Field." Contributions to Plasma Physics 51, no. 4 (May 2011): 401–4. http://dx.doi.org/10.1002/ctpp.201010109.

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30

Jorm, A. F., and P. Duncan-Jones. "Neurotic symptoms and subjective well-being in a community sample: different sides of the same coin?" Psychological Medicine 20, no. 3 (August 1990): 647–54. http://dx.doi.org/10.1017/s0033291700017165.

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SynopsisCommunity survey data on neurotic symptoms and subjective well-being scales were examined with principal components analysis. The two types of scales were found to load on separate, but negatively correlated, factors. Furthermore, some differential correlates of the two types of scale were found, but the differences were not great. It was concluded that neurotic symptom and well-being scales do largely measure different ends of a single continuum, but well-being scales seem to have an extraversion component not shared by neurotic symptom scales. Subjective well-being measures may be useful in epidemiological surveys where it is desirable to discriminate among low symptom scorers.
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31

Abdul Aziz, Ahmad Hazim, Nor Faadila Mohd Idrus, Nicky Rahmana Putra, Mohd Azrie Awang, Zuhaili Idham, Hasmadi Mamat, and Mohd Azizi Che Yunus. "Solubility of Rosmarinic Acid in Supercritical Carbon Dioxide Extraction from Orthosiphon stamineus Leaves." ChemEngineering 6, no. 4 (August 1, 2022): 59. http://dx.doi.org/10.3390/chemengineering6040059.

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Rosmarinic acid (RA) is present in a broad variety of plants, including those in the Lamiaceae family, and has a wide range of pharmacological effects, particularly antioxidant activity. To extract RA from Orthosiphon stamineus (OS) leaves, a Lamiaceae plant, a suitable extraction process is necessary. The present study used a green extraction method of supercritical carbon dioxide (SCCO2) extraction with the addition of ethanol as a modifier to objectively measure and correlate the solubility of RA from OS leaves. The solubility of RA in SCCO2 was determined using a dynamic extraction approach, and the solubility data were correlated using three density-based semi-empirical models developed by Chrastil, del Valle-Aguilera, and Gonzalez. Temperatures of 40, 60, and 80 °C and pressures of 10, 20, and 30 MPa were used in the experiments. The maximum RA solubility was found at 80 °C and 10 MPa with 2.004 mg of rosmarinic acid/L solvent. The RA solubility data correlated strongly with the three semi-empirical models with less than 10% AARD. Furthermore, the fastest RA extraction rate of 0.0061 mg/g min−1 was recorded at 80 °C and 10 MPa, and the correlation using the Patricelli model was in strong agreement with experimental results with less than 15% AARD.
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32

Hay, Phillipa J., Anne Hall, John W. Delahunt, Guy Harper, Alex W. Mitchell, and Clare Salmond. "Investigation of Osteopaenia in Anorexia Nervosa." Australian & New Zealand Journal of Psychiatry 23, no. 2 (June 1989): 261–68. http://dx.doi.org/10.3109/00048678909062144.

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Sixty-nine female patients, mean age 27.5 years (range 20-40), with a past or current history of anorexia nervosa (DSM Ill-R) had spinal trabecular bone density assessed by single energy quantitative CT scan. Current exercise and dietary calcium levels were assessed by detailed questionnaires and categorized. A semi-structured interview was used to record weight, menstruation, exercise and dietary calcium intake histories from early adolescence. Serum sex hormones and total calcium assays were measured. Bone density was significantly lower in the patients compared to 31 controls. Bone density was significantly positively correlated with body mass index, and negatively correlated with illness duration and duration of amenorrhoea. Exercise levels, dietary calcium intake and taking an oestrogen pill did not correlate significantly with bone density. Recovered patients did not have osteopaenia but they had shorter illness histories than non-recovered patients. Management to minimise bone loss should focus on weight gain and resumption of normal menstruation.
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33

Boyle-Makowski, R. M. D., and B. J. R. Philogène. "POLLINATOR ACTIVITY AND ABIOTIC FACTORS IN AN APPLE ORCHARD." Canadian Entomologist 117, no. 12 (December 1985): 1509–21. http://dx.doi.org/10.4039/ent1171509-12.

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AbstractThe activity of native and domestic insect pollinators was studied for 3 consecutive years, during the blossom period in a semi-dwarf apple orchard of the Niagara Peninsula. Insect numbers and activity were correlated with apple cultivars (Empire, McIntosh, Golden Delicious, Red Delicious) located on the east and west slopes of the orchard and with temperature, humidity, and light intensity fluctuations. The physical factors, especially temperature, were mainly responsible for the variation in the numbers of honeybees. Factors such as cultivar, east and west slopes, and year were more significant for native pollinators. Native pollinators less affected by adverse conditions seem to compensate for reduced honeybee activity during unfavorable years.
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34

Xiang, Xiaoling, and Jessica Brooks. "Correlates of Depressive Symptoms among Homebound and Semi-Homebound Older Adults." Journal of Gerontological Social Work 60, no. 3 (January 27, 2017): 201–14. http://dx.doi.org/10.1080/01634372.2017.1286625.

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35

dos Santos Costa, Adriana, Juliana Stropp, Nicolli Albuquerque de Carvalho, Fernanda Alves-Martins, Richard J. Ladle, and Ana C. M. Malhado. "Environmental correlates of seed weight of tropical semi-arid woody species." Plant and Soil 446, no. 1-2 (November 23, 2019): 369–78. http://dx.doi.org/10.1007/s11104-019-04341-1.

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36

Schmidt, R. S. "Neural correlates of frog calling: production by two semi-independent generators." Behavioural Brain Research 50, no. 1-2 (September 1992): 17–30. http://dx.doi.org/10.1016/s0166-4328(05)80284-0.

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37

Wang, Wei, Long Liang, Yaoli Peng, and Maria Holuszko. "Surface Chemical Heterogeneity of Low Rank Coal Characterized by Micro-FTIR and Its Correlation with Hydrophobicity." Minerals 11, no. 3 (February 25, 2021): 239. http://dx.doi.org/10.3390/min11030239.

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Micro-Fourier transform infrared (micro-FTIR) spectroscopy was used to correlate the surface chemistry of low rank coal with hydrophobicity. Six square areas without mineral impurities on low rank coal surfaces were selected as testing areas. A specially-designed methodology was applied to conduct micro-FTIR measurements and contact angle tests on the same testing area. A series of semi-quantitative functional group ratios derived from micro-FTIR spectra were correlated with contact angles, and the determination coefficients of linear regression were calculated and compared in order to identify the structure of the functional group ratios. Finally, two semi-quantitative ratios composed of aliphatic carbon hydrogen, aromatic carbon hydrogen and two different types of carbonyl groups were proposed as indicators of low rank coal hydrophobicity. This work provided a rapid way to predict low rank coal hydrophobicity through its functional group composition and helped us understand the hydrophobicity heterogeneity of low rank coal from the perspective of its surface chemistry.
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38

Chen, Jiajie, Anthony Hou, and Thomas Y. Hou. "A pseudo knockoff filter for correlated features." Information and Inference: A Journal of the IMA 8, no. 2 (July 17, 2018): 313–41. http://dx.doi.org/10.1093/imaiai/iay012.

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Abstract In Barber & Candès (2015, Ann. Statist., 43, 2055–2085), the authors introduced a new variable selection procedure called the knockoff filter to control the false discovery rate (FDR) and proved that this method achieves exact FDR control. Inspired by the work by Barber & Candès (2015, Ann. Statist., 43, 2055–2085), we propose a pseudo knockoff filter that inherits some advantages of the original knockoff filter and has more flexibility in constructing its knockoff matrix. Moreover, we perform a number of numerical experiments that seem to suggest that the pseudo knockoff filter with the half Lasso statistic has FDR control and offers more power than the original knockoff filter with the Lasso Path or the half Lasso statistic for the numerical examples that we consider in this paper. Although we cannot establish rigourous FDR control for the pseudo knockoff filter, we provide some partial analysis of the pseudo knockoff filter with the half Lasso statistic and establish a uniform false discovery proportion bound and an expectation inequality.
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39

Fernandez, M. Fernandez, B. Fernandez Llana, P. Fernandez Raigoso, M. C. Roiz, M. T. Allende, and A. Ruibal. "CAM26 Cytosol Levels Seem to be Correlated with pS2 Expression in Breast Cancer." International Journal of Biological Markers 8, no. 1 (January 1993): 25–26. http://dx.doi.org/10.1177/172460089300800105.

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40

Dhakal, Sunil, Philippa A. Martin, and Peter Smith. "Hybrid zero-forcing for correlated and semi-orthogonal multi-user MU-MIMO channels." IET Communications 13, no. 20 (December 19, 2019): 3575–81. http://dx.doi.org/10.1049/iet-com.2019.0167.

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41

Ng, Yin Hoe, Ai Hui Tan, and Teong Chee Chuah. "Iterative channel estimation for multiuser fibre‐wireless uplink exploiting semi‐correlated ternary signals." IET Signal Processing 10, no. 4 (June 2016): 395–403. http://dx.doi.org/10.1049/iet-spr.2015.0419.

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42

Ramezani, Mahdi, Mahdi Hajiaghayi, Chintha Tellambura, and Masoud Ardakani. "Receive antenna selection for unitary space-time modulation over semi-correlated Ricean channels." IEEE Transactions on Communications 58, no. 2 (February 2010): 521–30. http://dx.doi.org/10.1109/tcomm.2010.02.080664.

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43

Sterman, M. B., C. A. Mann, H. R. Eriksen, M. Olff, and H. Ursin. "Electroencephalographic Correlates of Psychological Defense." Proceedings of the Human Factors Society Annual Meeting 36, no. 1 (October 1992): 76–80. http://dx.doi.org/10.1177/154193129203600119.

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The Kragh tachistoscopic method for measuring psychological defense mechanisms (“Defense Mechanism Test” - DMT) has been claimed to be valid for selection of personnel for really dangerous tasks. The method consists of presenting a stimulus picture at initial exposure times that are too short for perception. To test whether this perceptual disturbance arises from an aberrant cognitive response to the situation, we studied the magnitude, topographic distribution, and temporal modulation of spectral density in the 8–12 Hz EEG frequency band during DMT testing in 22 male and 2 female active duty US Air Force personnel. Personnel with high defense mechanisms had significantly more attenuation of the 8–12 Hz activity during stimulus exposure than low defenders, implying an increased level of cortical activation. Personnel with low defense scores relax faster than those with high scores. The differences seem to occur even before threat is reported. High defense seems to require more and longer lasting data processing which may be too costly in dangerous situations.
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44

Paes, T. A. S. V., I. A. S. Costa, A. P. C. Silva, and E. M. Eskinazi-Sant’Anna. "Can microcystins affect zooplankton structure community in tropical eutrophic reservoirs?" Brazilian Journal of Biology 76, no. 2 (March 8, 2016): 450–60. http://dx.doi.org/10.1590/1519-6984.21014.

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Abstract The aim of our study was to assess whether cyanotoxins (microcystins) can affect the composition of the zooplankton community, leading to domination of microzooplankton forms (protozoans and rotifers). Temporal variations in concentrations of microcystins and zooplankton biomass were analyzed in three eutrophic reservoirs in the semi-arid northeast region of Brazil. The concentration of microcystins in water proved to be correlated with the cyanobacterial biovolume, indicating the contributions from colonial forms such as Microcystis in the production of cyanotoxins. At the community level, the total biomass of zooplankton was not correlated with the concentration of microcystin (r2 = 0.00; P > 0.001), but in a population-level analysis, the biomass of rotifers and cladocerans showed a weak positive correlation. Cyclopoid copepods, which are considered to be relatively inefficient in ingesting cyanobacteria, were negatively correlated (r2 = – 0.01; P > 0.01) with the concentration of cyanotoxins. Surprisingly, the biomass of calanoid copepods was positively correlated with the microcystin concentration (r2 = 0.44; P > 0.001). The results indicate that allelopathic control mechanisms (negative effects of microcystin on zooplankton biomass) do not seem to substantially affect the composition of mesozooplankton, which showed a constant and high biomass compared to the microzooplankton (rotifers). These results may be important to better understand the trophic interactions between zooplankton and cyanobacteria and the potential effects of allelopathic compounds on zooplankton.
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45

Dénarié, Delphine, Elodie Constant, Thierry Thomas, and Hubert Marotte. "Could Biomarkers of Bone, Cartilage or Synovium Turnover Be Used for Relapse Prediction in Rheumatoid Arthritis Patients?" Mediators of Inflammation 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/537324.

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Objective. The aim of this review is to clarify the usefulness of bone, cartilage, and synovial biomarker in the management of rheumatoid arthritis (RA) therapy in remission.Synovial Biomarkers. High MMP-3 levels are associated with joint progression in RA patients, but there is no data about their utility in clinical remission. IIINys and Glc-Gal-PYD seem to be more specific to synovium, but more studies are required.Cartilage Biomarkers. Unbalance between cartilage break-down biomarkers (urinary CTX II and COMP) and cartilage formation biomarker (PIIANP) was described. This unbalance is also associated with joint destruction and prognosis of destruction. No data are available on patients in remission.Bone Biomarkers. RA activity is correlated with an increase of bone resorption markers such as CTX I, PYD, and TRACP 5b and a decrease of bone formation markers such as OC and BALP. RA therapies seem to improve bone turnover in limiting bone resorption. There is no study about bone marker utility in remission.Conclusion. Biomarkers seem to correlate with RA activity and progression. They also could be used to manage RA therapies, but we need more data on RA remission to predict relapse.
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46

Hsiao, Cheng, Qi Li, Zhongwen Liang, and Wei Xie. "Panel Data Estimation for Correlated Random Coefficients Models." Econometrics 7, no. 1 (February 1, 2019): 7. http://dx.doi.org/10.3390/econometrics7010007.

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This paper considers methods of estimating a static correlated random coefficient model with panel data. We mainly focus on comparing two approaches of estimating unconditional mean of the coefficients for the correlated random coefficients models, the group mean estimator and the generalized least squares estimator. For the group mean estimator, we show that it achieves Chamberlain (1992) semi-parametric efficiency bound asymptotically. For the generalized least squares estimator, we show that when T is large, a generalized least squares estimator that ignores the correlation between the individual coefficients and regressors is asymptotically equivalent to the group mean estimator. In addition, we give conditions where the standard within estimator of the mean of the coefficients is consistent. Moreover, with additional assumptions on the known correlation pattern, we derive the asymptotic properties of panel least squares estimators. Simulations are used to examine the finite sample performances of different estimators.
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47

Miley, William M., Sonia V. Gonsalves, and Alan Arcuri. "Types of College Student-to-Student Learning: Correlated Interactions." Psychological Reports 94, no. 1 (February 2004): 257–58. http://dx.doi.org/10.2466/pr0.94.1.257-258.

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209 college men and 327 college women took a 20-item Likert survey to assess the types of education-related information students may learn from other students during their informal interactions. Students were very likely to ask other students low level questions such as which professors were good and which classes to take. They were less likely to ask other students about concepts discussed in class and how to solve problems generated in class. If students asked about test taking, these students were also likely to ask about study skills and writing skills for the class. Other research suggests these higher level help-seeking behaviors seem to be related to classroom mastery and achievement.
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48

Adler, Jeremy, Richard Colletti, Lenore Noonan, Laurie Conklin, Kim Hung Lo, Yongling Xiao, and Sheri Volger. "VALIDATION OF THE SIMPLIFIED ENDOSCOPIC MUCOSAL ASSESSMENT OF CROHN’S DISEASE (SEMA-CD) A NOVEL ENDPOINT TO ASSESS ENDOSCOPIC IMPROVEMENT WITH REAL WORLD DATA." Inflammatory Bowel Diseases 28, Supplement_1 (January 22, 2022): S35—S36. http://dx.doi.org/10.1093/ibd/izac015.053.

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Abstract BACKGROUND To demonstrate treatment efficacy in Crohn’s disease (CD), regulatory authorities require that trials include an endoscopic remission endpoint. However, standardized endoscopic assessment of mucosal improvement, such as the simple endoscopic score of CD (SES-CD), is not typically recorded by clinicians in practice or outside of clinical trials. A previous study demonstrated the Simplified Endoscopic Mucosal Assessment of CD (SEMA-CD) correlates strongly with SES-CD and that SEMA-CD is a score that can be easily used by clinicians in routine practice (Adler et al., 2021). The objective of this current study was to validate the SEMA-CD scored colonoscopy videos in additional populations and to examine the reliability of SEMA-CD over a range of mucosal disease severity in pediatric and adult participants and to evaluate sensitivity to change over time. METHODS We compared SEMA-CD and SES-CD scores in 110 patients with existing pre- and post-treatment colonoscopy videos from two ustekinumab clinical trials (UNISTAR, pediatric, n=36; SEAVUE, adult, n=74; Figure 1). Videos were separately scored with the SEMA-CD and SES-CD by different central readers, blinded to each other’s scores and to clinical history. Spearman’s rank correlation coefficient was used to evaluate correlation between scores, under different settings by study population (pediatric, adult), disease severity, and video quality. Inter- and intra-rater reliability were assessed with interclass correlation coefficient (ICC). Readers also rated ease of SEMA-CD scoring on a 7-point Likert scale. RESULTS SEMA-CD was highly correlated (rho [95% CI]) with the SES-CD, 0.89 (0.86, 0.92; Figure 2). Pre-to post-treatment changes in SEMA-CD scores compared with SES-CD scores were highly correlated 0.84 (0.77, 0.89). The positive relationship remained strong between scores when comparing total scores in pediatric 0.94 (0.90, 0.96) and adult 0.86 (0.80, 0.89) participants; across SES-CD disease severity categories (inactive, mild, moderate, severe; rho range 0.69-0.85); and in “optimal” 0.90 (0.86, 0.93) and “less than optimal” quality videos 0.88 (0.83, 0.91). Intra- and inter-reader reliability (ICC [95%CI]) were high, 0.93 (0.88, 0.96) and 0.89 (0.85, 0.91), respectively. SEMA-CD was rated as the same as, or easier than SES-CD 99.6% of the time. CONCLUSION This study demonstrated the SEMA-CD is feasible, reliable, reproducible, and sensitive to change in both adult and pediatric patients with CD. SEMA-CD should serve as an easy score for clinicians to record mucosal improvement and provide quality real world evidence for research using data from clinical registries.
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49

Nagel, Frederik, Reinhard Kopiez, Oliver Grewe, and Eckart Altenmüller. "Psychoacoustical correlates of musically induced chills." Musicae Scientiae 12, no. 1 (March 2008): 101–13. http://dx.doi.org/10.1177/102986490801200106.

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Music listening is often accompanied by the experience of emotions, sometimes even by so-called “strong experiences of music” (SEMs). SEMs can include such pleasurable reactions as shivers down the spine or goose pimples, which are referred to as “chills”. In the present study, the role of psychoacoustical features was investigated with respect to the experience of chills. Psychoacoustical parameters of short musical segments (total duration: 20 s), characterized as chill- inducing, were analyzed and compared with musical excerpts which did not induce chill responses. A significant increase of loudness in the frequency range between 8 and 18 Bark (920–4400 Hz) was found in those excerpts for which chills were reported. Frequency-dependent changes of loudness seem to play an important role in the induction of chills.
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50

Fichna, Marta, Agata Czarnywojtek, Anna Sowińska, Maria Gryczyńska, Paweł Gut, and Marek Ruchała. "Serum Visfatin does not seem to be a Useful Marker to Guide Glucocorticoid Substitution in Adrenal Insufficiency." Hormone and Metabolic Research 52, no. 05 (April 6, 2020): 322–28. http://dx.doi.org/10.1055/a-1135-9715.

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AbstractPrimary adrenal insufficiency (Addison’s disease, AD) requires lifelong steroid substitution. Excess exogenous glucocorticoids promote abdominal obesity, insulin-glucose imbalance, and hypertension. Reliable markers of the adequate glucocorticoid replacement are lacking. Visfatin is a pro-inflammatory adipokine, with enzymatic activity of nicotinamide phosphoribosyltransferase. It enhances leukocyte function and synthesis of tumour necrosis factor α (TNFα) and interleukin-6 (IL-6). Serum visfatin is elevated in autoimmunity, but also in obesity, insulin resistance, and metabolic syndrome. This study was aimed to investigate whether serum visfatin could guide the glucocorticoid substitution in AD. Biochemical analyses were performed in 96 patients with AD (mean age 43.3±14.9 years) and 91 controls (43.5±12.5 years). Visfatin level was significantly elevated in patients with AD compared to controls (p<0.0001). Higher circulating IL-6 was also detected among subjects with AD (p=0.006). In AD, visfatin level was positively correlated with IL-6 (p=0.014), TNFα (p=0.001), body mass (p=0.015), fasting insulin (p=0.001) and HOMA-IR (p=0.001). No relationship was noticed with daily hydrocortisone (p=0.096) and urinary free cortisol excretion (p=0.499). Only the correlations with IL-6 and fasting insulin survived multiple regression analysis (p=0.049 and p=0.005, respectively). Additionally, positive correlation between visfatin and autoantibodies to 21-hydroxylase was noted (p=0.005). In the control group serum visfatin was correlated with IL-6 (p=0.009) and TNFα (p=0.0002). The current study reveals elevated serum visfatin in autoimmune AD. Visfatin does not seem a useful marker of the glucocorticoid replacement, although it correlates with fasting insulin and pro-inflammatory molecules. Further functional analyses are warranted to elucidate the role of visfatin in autoimmunity.
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