Добірка наукової літератури з теми "Complex antioxidant"

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Статті в журналах з теми "Complex antioxidant"

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Yang, Hui, Li Li, Fu Xin Yang, Ying Yue Zhou, Li Juan Ou, and Shuai Feng Hu. "Preparation and Properties of Complex Antioxidants LDPE Antioxidant Film." Advanced Materials Research 989-994 (July 2014): 519–22. http://dx.doi.org/10.4028/www.scientific.net/amr.989-994.519.

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Low density polyethylene (LDPE) films contains BHA, BHT or BHA, BHT, TA were successfully produced by extrusion. Three types of antioxidant films that were L(LDPE), LBB(LDPE+0.5%BHA+0.5%BHT), and LBBT(LDPE+0.5%BHA+0.5%BHT+0.5%TA) was designed. The Mechanics, moisture permeability, scanning electron microscopy (SEM) and antioxidant activity of the film were detected. The results showed that antioxidant consisting of BHA, BHT and TA has a better compatibility with LDPE film. The antioxidant film has a better performance on mechanical strength and the rate of DPPH radical scavenging ability, but poor to water vapor transmission rate.
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Azizah, Rafida, Tintrim Rahayu, Ari Hayati, and Gatra Ervi Jayanti. "Scavenging activity nano complex compounds of kelor (Moringa oleifera Lamk.) leaves and seeds." Berkala Penelitian Hayati 26, no. 1 (December 24, 2020): 26–31. http://dx.doi.org/10.23869/bphjbr.26.1.20205.

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Moringa oleifera Lamk. is a good source of natural antioxidants because it contains various types of antioxidant compounds such as ascorbic acid, flavonoids, phenolics, and carotenoids. Those antioxidant components forming complex structure have transitional metal as central compound, which have free radical scavenging activity. This study aims to determine the active compounds that act as scavenger in leaves and seeds of M. oleifera. The possible compound found in leaves-seeds is elaborated by in silico analysis, using Dr. Dukes Phytochemical and Ethnobotanical Databases, by mean Pass online, and HitPick software. The results of in silico analysis 3 compounds identified in the leaves that had a high antioxidant role, namely beta-carotene, kaempferol, quercetin, and 2 compounds in seeds that had a high antioxidant role, namely alpha-tocopherol, beta-carotene. The results of this study indicate that the antioxidant activity of the 3 treatments had differences effectiveness of antioxidants. All of these antioxidants has ability to bind transitional metal to form free radical scavenger.
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Decker, Eric, and Ipek Bayram. "Why does lipid oxidation in foods continue to be such a challenge?" INFORM International News on Fats, Oils, and Related Materials 32, no. 5 (May 1, 2021): 18–23. http://dx.doi.org/10.21748/inform.05.2021.18.

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Lipid reactions are extremely complex because they involve numerous prooxidants, antioxidants, and lipid substrates whose reactivity is impacted by the physical properties of complex food systems. Understanding the interactions between the factors impacting lipid oxidation reactions is key to developing novel antioxidant strategies. Synergistic antioxidant combinations represent a promising approach to decreasing oxidative rancidity if how and where they work can be better understood.
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Ushakova, Nina A., Efim S. Brodsky, Olga V. Tikhonova, Alexander E. Dontsov, Maria V. Marsova, Andrey A. Shelepchikov, and Alexander I. Bastrakov. "Novel Extract from Beetle Ulomoides dermestoides: A Study of Composition and Antioxidant Activity." Antioxidants 10, no. 7 (June 30, 2021): 1055. http://dx.doi.org/10.3390/antiox10071055.

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A biologically active extract from the darkling beetle Ulomoides dermestoides was obtained using the electro-pulse plasma dynamic extraction method. The beetle water extract contained a complex of antioxidant substances such as antioxidant enzymes and nonprotein antioxidants, as well as a complex of heat shock antistress proteins. This determines the rather high antioxidant activity of the aqueous extract of the beetle, i.e., 1 mg of dry matter/mL of the extract has an equivalent antioxidant activity to 0.2 mM Trolox (a water-soluble analog of vitamin E). It was shown that the beetle extract can lead to a 25–30% increase in the average lifespan of nematode Caenorhabditiselegans, under normal conditions, and a 12–17% increase under conditions of oxidative stress (with paraquat), and significantly inhibits the fructosylation reaction of serum albumin. Therefore, the beetle aqueous extract shows promise as a biologically active complex exhibiting antioxidant activity.
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Viktorova, Jitka, Milena Stranska-Zachariasova, Marie Fenclova, Libor Vitek, Jana Hajslova, Vladimir Kren, and Tomas Ruml. "Complex Evaluation of Antioxidant Capacity of Milk Thistle Dietary Supplements." Antioxidants 8, no. 8 (August 18, 2019): 317. http://dx.doi.org/10.3390/antiox8080317.

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Numerous in vitro assays are used to characterize the antioxidant properties of natural-based matrices. However, many of them generate contradictory and non-compliant results. In our study, we focused on the characterization of traditionally used biochemical (2,2′-azino-bis-(3-ethylbenzothiazoline-6 sulfonic acid) (ABTS), Oxygen Radical Absorption Capacity (ORAC), and 2,2-diphenyl-1-picrylhydrazyl (DPPH)) and cellular (CAA) antioxidant tests on a broad set of milk thistle dietary supplements containing silymarin. In addition to 26 commercially available preparations, also the natural silymarin extract available from Sigma Aldrich, St. Louis, MI, USA, and a model mixture of pure flavonoid/flavonolignans mimicking the silymarin composition were investigated as control samples. Significant differences in the antioxidant capacity of the supplements were observed. Unlike the DPPH, the results of the ABTS and ORAC methods correlated with the silymarin components determined by U-HPLC-HRMS/MS. The responses in CAA were considerably lower than in other assays. Silymarin exhibited a significantly higher antioxidant capacity than the artificially prepared flavonoid/flavonolignans mixture in all tests, indicating possible presence of other antioxidants of natural origin. The follow-up U-HPLC-HRMS/MS screening revealed the presence of tens of non-silymarin compounds with reported antioxidant activity (not only in the silymarin extract, but also in the milk thistle preparations). The sum of the total phenolics and the sum of the simple phenolics correlated with CAA results more than silymarin.
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Nagamine, I., H. Sakurai, H. T T Nguyen, M. Miyahara, J. Parkányiová, Z. Réblová, and J. Pokorný. "Antioxidant activity of acerola extracts." Czech Journal of Food Sciences 22, SI - Chem. Reactions in Foods V (January 1, 2004): S155—S158. http://dx.doi.org/10.17221/10645-cjfs.

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West Indian cherries or acerola fruits (Malpighia glabra L.) are very rich in ascorbic acid, and also contain flavonoids and anthocyanins. Therefore, their antioxidant activity is interesting. Aqueous and methanolic acerola extracts increased the stability of β-carotene-linoleic acid emulsions against oxidation. Flavonoids and anthocyanins obviously enhanced the effect of ascorbic acid. The effect of natural acerola antioxidants was comparable to that of phenolic antioxidants, such as ferulic acid. During the determination of antioxidant activity in emulsions, carotene was destroyed following a complex kinetics in the beginning of oxidation, but the zeroth order kinetics in later stages of oxidation.
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Bazhenova, Bayana, Anastasia Burkhanova, Yuliya Zabalueva, and Roman Dobretsky. "Immobilization of Daurian Rosehip Antioxidants by Protein-Lipid Inclusion." Food Processing: Techniques and Technology 51, no. 2 (June 15, 2021): 301–11. http://dx.doi.org/10.21603/2074-9414-2021-2-301-311.

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Introduction. Antioxidant system is one of the main cellular mechanisms of adaptation. It is able to neutralize the destructive effect of free radicals, both external and internal. Functional products, especially of meat origin, can provide necessary antioxidant properties. Some types of plant raw materials possess a high content of polyphenol complexes with antioxidant properties. Therefore, introduction of phytonutrients into the composition of meat products can help to expand the range of foods with an antioxidant effect. Daurian rosehip is rich in biologically active substances and can increase their safety during processing. The research objective was to study the possibility of immobilization of Daurian rosehip antioxidants by protein-lipid inclusion. Study objects and methods. The research featured fruits of Daurian rosehip, its aqueous alcoholic extract, and protein-lipid complex. Results and discussion. The article presents experimental data on the chemical composition of Daurian rosehip. The optimal method with the best antioxidant results was a microwave phytoextraction by an aqueous alcoholic solution at a power of 800 W for 6–7 min. The antioxidants were immobilized by including the protein-lipid complex into the gel. The experiment demonstrated excellent functional and technological characteristics of the resulting system. Conclusion. The research revealed the optimal modes of microwave extraction of biologically active substances of Daurian rosehip. The rosehip extract was included into the protein-lipid complex and immobilized antioxidants, thus increasing their efficiency.
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Apak, Reşat, Shela Gorinstein, Volker Böhm, Karen M. Schaich, Mustafa Özyürek, and Kubilay Güçlü. "Methods of measurement and evaluation of natural antioxidant capacity/activity (IUPAC Technical Report)." Pure and Applied Chemistry 85, no. 5 (February 26, 2013): 957–98. http://dx.doi.org/10.1351/pac-rep-12-07-15.

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Анотація:
The chemical diversity of natural antioxidants (AOXs) makes it difficult to separate, detect, and quantify individual antioxidants from a complex food/biological matrix. Moreover, the total antioxidant power is often more meaningful to evaluate health beneficial effects because of the cooperative action of individual antioxidant species. Currently, there is no single antioxidant assay for food labeling because of the lack of standard quantification methods. Antioxidant assays may be broadly classified as the electron transfer (ET)- and hydrogen atom transfer (HAT)-based assays. The results obtained are hardly comparable because of the different mechanisms, redox potentials, pH and solvent dependencies, etc. of various assays. This project will aid the identification and quantification of properties and mutual effects of antioxidants, bring a more rational basis to the classification of antioxidant assays with their constraints and challenges, and make the results more comparable and understandable. In this regard, the task group members convey their own experiences in various methods of antioxidants measurement.
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Raksha, N., Ju Sokolovskaya, E. Manzhaliy, D. Dobryanskiy, and O. Savchuk. "Estimation of antioxidant properties of experimental poly-component complexes." Bulletin of Taras Shevchenko National University of Kyiv. Series: Biology 82, no. 3 (2020): 63–66. http://dx.doi.org/10.17721/1728_2748.2020.82.63-66.

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The involvement of free radicals appears to be the feature of most human diseases. The general mechanism of cell damage involves the excessive uncontrolled production of reactive oxygen species resulting in the intensification of lipid peroxidation processes and damaging of macromolecules. These processes are generally accompanied by a decrease in the concentration and/or activity of natural antioxidants. Moreover, the exhaustion of the antioxidant capacity of the organism is among the key reasons leading to the development of pathological states. The maintenance of the prooxidant-antioxidant balance by the systematic use of products or dietary supplements, the components of which exhibit antioxidant activity, can be considered as a part of a strategy for the prevention and control of diseases associated with oxidative stress. The current work aims to study the free radical scavenging activity of two experimental poly-component complexes. Antioxidant properties of complexes were determined in experiments in vitro. The estimation of total antioxidant activity, nitric oxide, hydrogen peroxide radical, and superoxide anion scavenging activity was performed. The results revealed that both complexes have the potentials to prevent the formation of free radicals and can be used as agents with antioxidant properties. It was established that the effect of complex 1 and 2 is complex and first of all aimed at the prevention of the formation of dangerous free radicals by reducing the level of hydrogen peroxide. The additional mechanism involves the chelating of metal ions, in particular ferrous iron. The antioxidant ability exhibited by complex 1 was found to be higher than the total antioxidant activity of complex 2. Complex 1 was more effective in the ability to neutralize superoxide anion-radicals while complex 2 showed a high percentage inhibition of Fe2+-induced lipid peroxidation.
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Angeli, Lucrezia, Sebastian Imperiale, Yubin Ding, Matteo Scampicchio, and Ksenia Morozova. "A Novel Stoichio-Kinetic Model for the DPPH• Assay: The Importance of the Side Reaction and Application to Complex Mixtures." Antioxidants 10, no. 7 (June 24, 2021): 1019. http://dx.doi.org/10.3390/antiox10071019.

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The 2,2-diphenyl-1-picrylhydrazyl (DPPH•) assay is widely used to determine the antioxidant activity of food products and extracts. However, the common DPPH• protocol uses a two-point measurement and does not give information about the kinetics of the reaction. A novel stoichio-kinetic model applied in this study monitors the consumption of DPPH• by common antioxidants following the second order reaction. The fitting of such decay yields the rate constant k1, which describes the main reaction between antioxidants and DPPH•, and the rate constant k2, which is attributed to a slower side reaction considering the products generated between the transient radicals (AO•) and another molecule of DPPH•. The model was first applied to antioxidant standards. Sinapic acid, Trolox and ascorbic and chlorogenic acids did not show any side reaction. Instead gallic, ferulic and caffeic acids achieved the best fitting with k2. The products of the side reaction for these compounds were confirmed and identified with high-resolution mass spectrometry. Finally, the kinetic model was applied to evaluate the antioxidant activity of eight herbal extracts. This study suggests a new kinetic approach to standardize the common DPPH• assay for the determination of antioxidant activity.
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Дисертації з теми "Complex antioxidant"

1

Liu, Zheng-Xian. "Antioxidant activity of Mn-salophen complex and its effects on antioxidant enzymes in Escherichia coli." Diss., Virginia Tech, 1994. http://hdl.handle.net/10919/40046.

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Mn-salophen complex with superoxide-scavenging activity was prepared from manganese(III) acetate dihydrate and salophen in ethanol. Visible absorption spectrum of the red-brown solution exhibited a broad absorption band at 430 - 450 nm with two shoulders between 500 and 600 nm which were absent with either salophen or manganic acetate alone. Titration of salophen with manganese(III) was consistent with a 1:1 Mn to salophen stoichiometry of the complex based on changes in the absorbance at 500 nm or of superoxide scavenging activity. The SOD-like activity of the complex in the xanthine-xanthine oxidase/cytochrome c assay was 1450 units/mg salophen. The SOD activity of the complex was suppressed 50% in the presence of EDTA (1 mM), but was not altered in the presence of bovine serum albumin (1 mg/ml) or crude protein extract of E. coli QC779 sodA sodB (1 mg/ml). E. coli QC779 sodA sodB grew scantily after an 8 hour lag phase in aerobic M63 glucose minimal medium.
Ph. D.
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Kim, Youngmok. "Factors influencing antioxidant phytochemical stability of teas." [College Station, Tex. : Texas A&M University, 2008. http://hdl.handle.net/1969.1/ETD-TAMU-3172.

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Killmukhametova, Yu H. "Concentration of general immune complexes in experimental animals with and without the local treatment of gingivitis with the complex antioxidant therapy." Thesis, БДМУ, 2020. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/17832.

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Bottari, Nathieli Bianchin. "RESVERATROL LIVRE E EM COMPLEXO DE INCLUSÃO ASSOCIADO AO SULFAMETOXAZOL-TRIMETROPIM EMCAMUNDONGOS INFECTADOS EXPERIMENTALMENTE COM Toxoplasma gondii." Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/11249.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
The Toxoplasma gondii is a protozoan of great clinical importance can cause functional and biochemical changes in the host cells mainly in the central nervous system. These changes are usually associated with the inflammatory response to tissue damage and cell oxidation in immunocompetent hosts. T. gondii infection stimulate the production of high levels of cytokines such as IL-12 and IFN-γ by cells of the immune system, consisting of a main point in parasite control and disease resistance. As a potent antioxidant, resveratrol has become an important research subject due to its antioxidant and anti-inflammatory properties. However, the mechanism by which resveratrol exerts its effects are hampered by the low solubility and bioavailability. Accordingly, one way to improve the bioavailability of resveratrol is to associate with inclusion complexes. Thus, this study aimed to investigate the benefits of resveratrol associated with sulfamethoxazole-trimethoprim (ST) in the treatment of experimentally infected mice with T. gondii. For the study, 60 mice were divided into two groups: non-infected (n = 24) and infected with T. gondii (n = 36). The two groups were divided into subgroups and treated with resveratrol (free and inclusion complex 2-hydroxypropyl-β-cyclodextrin) isolated and associated with ST. The groups A to D composed by healthy mice and groups E to J consisting of animals infected by T. gondii (VEG strain). The treatment started 20 days post-infection for 10 consecutive days with oral doses of 0.5 mg kg-1 of ST (groups B and F), 100 mg kg-1 of free resveratrol (groups C and G) and inclusion complex of resveratrol (inclusion complex containing resveratrol) (groups D and H), as well as with an association of both drugs (groups I and J). Groups A and E were used as control, untreated. Behavioral tests (memory, anxiety and locomotion) were performed after treatment. Blood samples, liver and brain fragments were collected to evaluate the cytokine profile, pathological changes, brain cysts counts, as well as oxidant/antioxidant profile. Infected animals showed behavioral changes such as anxiety and memory loss. The combination ST and resveratrol was able to restore time latência in passive avoidance task. A reduction of the number of brain cyst was observed on animals treated with the combination of drugs. Infected animals show an increase in pro-inflammatory cytokines and reduction of anti-inflammatory cytokine (IL-10), as well as increased protein oxidation in liver and brain tissue. The combination of resveratrol and ST with free inclusion complex in increased the total antioxidant capacity (TAC) and ferric reducing antioxidant power (FRAP) levels in liver and brain that can be interpreted by the protective effect of resveratrol. In addition, resveratrol in inclusion complex form when combined with ST improved therapeutic effect of ST reducing oxidative damage in liver and brain, reducing the number of cysts in the treatment of mice infected with T. gondii. Therefore, it is possible to suggest that the ST with resveratrol on treatment of infected mice can exerts a protective effect on host cells. The resveratrol in inclusion complex form was the best treatment option, for controlled tissue and serum immune responses, as well as oxidative stress in mice infected with T. gondii.
O Toxoplasma gondii é um protozoário de grande importância clínica capaz de ocasionar alterações bioquímicas e funcionais nas células do hospedeiro, principalmente no sistema nervoso central. Essas alterações, geralmente estão associadas à resposta inflamatória com danos teciduais e oxidação celular em hospedeiros imunocompetentes. A infecção por T. gondii estimula a produção de altos níveis de citocinas, tais como IL-12 e IFN-γ, pelas células do sistema imunológico, consistindo em um ponto principal no controle do parasito e resistência à doença. Como um potente antioxidante, o resveratrol tem se tornado um importante alvo de pesquisas graças a suas propriedades antioxidantes e anti-inflamatórias. No entanto, os mecanismos pelo qual o resveratrol exerce seu efeito são prejudicados pela baixa solubilidade e biodisponibilidade. Nesse sentido, uma forma de melhorar a biodisponibilidade do resveratrol é associá-lo a um complexo de inclusão. Desta maneira, os objetivos deste estudo foram investigar os benefícios do resveratrol associado a sulfamethoxazol-trimetropin (ST) no tratamento de camundongos infectados experimentalmente com T. gondii. Para o estudo, 60 camundongos foram divididos em dois grupos: não-infectados (n=24) e infectados com T.gondii (n=36). Os dois grupos foram subdivididos em subgrupos (n= 10) e tratados com resveratrol (livre e em complexo de inclusão 2- hidroxipropil-β-ciclodextrina) isolado e associado com ST. Os grupos A-D foram compostos por animais saudáveis; grupos E-J consistiram de animais infectados por T. gondii (cepa VEG). O tratamento foi iniciado 20 dias após a infecção e manteve-se por 10 dias consecutivos nas doses orais de 0.5 mg kg-1 de ST (grupos B e F), 100 mg kg-1 de resveratrol livre (grupos C e G) e na forma de complexo de inclusão (grupos D e H), bem como na associação de ambas drogas (grupos I e J). Grupos A e E foram usados como controles, não tratados. Testes comportamentais (memória, ansiedade e locomoção) foram avaliados após o tratamento. Amostras de sangue, fragmentos de fígado e cérebro foram coletados a fim de avaliar os níveis de citocinas, alterações histopatológicas, contagem de cistos cerebrais, como também perfil oxidativo/antioxidante. Animais infectados com T. gondii apresentaram alterações comportamentais como ansiedade e perda de memória. A combinação com ST e resveratrol foi capaz de restaurar o tempo de latência no teste de esquiva inibitória. Uma redução na contagem de cistos foi observada nos animais tratados com a associação de drogas assim como redução das lesões teciduais. Animais infectados apresentam aumento de citocinas pró-inflamatórias e redução da citocina anti-inflamatória (IL-10), assim como maior oxidação proteica em tecido hepático e cerebral. A combinação de ST com resveratrol livre e em complexo de inclusão aumentou os a capacidade antioxidante total (TAC) e os produtos de redução férrica (FRAP) em fígado e cérebro que pode ser interpretado pelo efeito protetor do resveratrol. Além disso, o resveratrol na forma de complexo de inclusão quando combinado à ST melhorou o efeito terapêutico da ST reduzindo os danos oxidativos, lesões hepáticas e número de cistos cerebrais no tratamento de camundongos infectados com T. gondii. Portanto, é possível sugerir que a combinação de ST com resveratrol em camundongos infectados parece exercer um efeito protetor nas células hospedeiras. O resveratrol na forma de complexo de inclusão foi a melhor opção terapêutica, pois controlou as respostas imunológicas séricas e teciduais, assim como o estresse oxidativo em camundongos infectados com T. gondii.
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Hyardin, Aude. "Étude de la fonctionnalité alimentaire de plats industriels." Thesis, Vandoeuvre-les-Nancy, INPL, 2008. http://www.theses.fr/2008INPL038N/document.

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Consommateurs, chercheurs et industriels cherchent de plus en plus à associer à la valeur nutritionnelle des aliments, un effet bénéfique pour la santé. Les aliments caractérisés par des pouvoirs antioxydants élevés semblent correspondre à cette demande. En effet, plusieurs travaux mentionnent les bénéfices santé de ces aliments. Pour répondre à cette demande les industriels mettent en avant ce critère. La fonctionnalité alimentaire, aux bénéfices prometteurs pour la santé publique, reste un concept néanmoins complexe dans la pratique. Ce travail met l’accent sur le fait que les propriétés fonctionnelles d’un aliment ne sont pas directement liées à la composition en ingrédients. L’évaluation du pouvoir antioxydant d'un aliment est dans la plupart des cas réalisée à partir des valeurs des différents ingrédients avant formulation et mise en œuvre des procédés. Pourtant, plusieurs phénomènes sont susceptibles de modifier le pouvoir antioxydant lors de la durée de vie d'un produit alimentaire. D’un point de vue industriel, il est nécessaire de développer une méthode de prédiction de cette activité. Les objectifs de ce travail étaient d’adapter une méthode reproductible et facile à réaliser de quantification du pouvoir antioxydant sur des aliments complexes et de comparer cet index d'un ensemble de produits contenant une large gamme de matières premières. Enfin, a été discuté l’intérêt que représente, dans le domaine des propriétés anti oxydantes, la quantification de l’index créé. Au moment où les industriels vont être amenés à proposer des allégations liées à l’effet bénéfique de l’aliment choisi parmi un échantillon de plus en plus ample
Consumers, researchers and industrialists try more and more to associate with the nutritional value of food, a beneficial effect for the health. Food characterized by high antioxidant powers seems to correspond to this demand. From an industrial point of view, it is necessary to develop methods of predicting this antioxidant capacity. The objectives of this work were to adapt a method reproducible and easy to realize of quantification of the antioxidant power on complex food and to compare this index of a set of products containing a wide range of raw materials. Until now, it has been considered that the use of raw materials characterized by a high antioxidant capacity also leads to a preparation with a high antioxidant activity. We evaluated many of the factors affecting the antioxidant activity of convenience foods (phenol content, effects of formulation, culinary reheating, and preservation) and to provide data on convenience foods consumed by the French population. The total antioxidant capacity of the ethanolic extracts was evaluated by the method of the equivalent Trolox (TEAC) using the radical cation ABTS•+. The concentration of the total phenolic compounds of the same extracts was determined by the Folin-Ciocalteu method. The results show that the food matrix is an important factor for the modulation of activities of antioxidants. A standardised testing protocol for evaluating antioxidative effects is necessary. Then, we discussed the interest of an index, as the industrialists are going to be brought to claim to the beneficial effect of the food chosen among a more and more ample sample
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Cottrell, Catherine E. "Genetic variation and complex disease: the examination of an X-linked disorder and a multifactorial disease." The Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=osu1196182829.

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7

Koontz, John L. "Controlled Release of Natural Antioxidants from Polymer Food Packaging by Molecular Encapsulation with Cyclodextrins." Diss., Virginia Tech, 2008. http://hdl.handle.net/10919/26757.

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Synthetic antioxidants have traditionally been added directly to food products in a single initial dose to protect against oxidation of lipids and generation of free radicals. Natural antioxidants have been shown to undergo loss of activity and become prooxidants at high concentrations; therefore, a need exists to develop active packaging which can gradually deliver antioxidants in a controlled manner. The objectives of this research were to (1) form and characterize cyclodextrin inclusion complexes with the natural antioxidants, alpha-tocopherol and quercetin, (2) incorporate cyclodextrin inclusion complexes of natural antioxidants into linear low density polyethylene (LLDPE), and (3) measure the release kinetics of inclusion complexes of natural antioxidants from LLDPE into a model food system. Cyclodextrin inclusion complexes of alpha-tocopherol and quercetin were formed by the coprecipitation method and characterized in the solid state by NMR, IR spectroscopy, and thermal analyses. Solid inclusion complex products of alpha-tocopherol:beta-cyclodextrin and quercetin:gamma-cyclodextrin had molar ratios of 1.7:1 as determined by UV spectrophotometry, which were equivalent to 18.1% (w/w) alpha-tocopherol and 13.0% (w/w) quercetin. Free and cyclodextrin complexed antioxidant additives were compounded with a twin-screw mixer into two LLDPE resin types followed by compression molding into films. Release of alpha-tocopherol and quercetin from LLDPE films into coconut oil at 30 °C was quantified by HPLC during 4 weeks of storage. The total release of alpha-tocopherol after 4 weeks was 70% from the free form and 8% from the complexed form averaged across both LLDPE resins. The mechanism by which alpha-tocopherol was released was modified due to its encapsulation inside the beta-cyclodextrin cavity within the LLDPE matrix as indicated by its diffusion coefficient decreasing by two orders of magnitude. Molecular encapsulation of natural antioxidants using cyclodextrins may be used as a controlled release mechanism within polymer food packaging to gradually deliver an effective antioxidant concentration to a food product, thereby, limiting oxidation, maintaining nutritional quality, and extending shelf life.
Ph. D.
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Trombley, John D. "Polyphenols: Interactions with proteins and analytical methods." Miami University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=miami1322841396.

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Comunian, Talita Aline. "Microencapsulação de ácido ascórbico por coacervação complexa e dispositivos microfluídicos: estudo estrutural, estabilidade e aplicação das microcápsulas." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/74/74132/tde-03122013-162024/.

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Reações de oxidação lipídica são responsáveis pelo desenvolvimento de sabores e odores desagradáveis tornando os alimentos impróprios para consumo, sendo necessário o uso de antioxidantes. O ácido ascórbico (AA) é um antioxidante muito eficaz, que exibe função vitamínica, no entanto é relativamente instável. Com o objetivo de aumentar a estabilidade do AA e, consequentemente, facilitar sua aplicação em produtos alimentícios, os métodos de encapsulação por coacervação complexa e por dispositivos microfluídicos foram testados. Primeiramente foi apresentada a Revisão Bibliográfica no Capítulo 1, e em seguida, a encapsulação por coacervação complexa, como será visto no Capítulo 2. Neste caso, nove tratamentos foram obtidos utilizando-se gelatina e goma arábica como materiais de parede e analisados com relação à morfologia, por microscopia ótica e eletrônica de varredura, umidade, atividade de água, higroscopicidade, solubilidade, potencial zeta, espectroscopia no infravermelho por transformada de Fourier (Ftir), tamanho e distribuição de tamanho de partículas, cor instrumental, eficiência de encapsulação e estabilidade do material encapsulado. No capítulo 3 serão apresentados resultados obtidos na encapsulação do AA pelo método de dispositivos microfluídicos. Cinco tratamentos foram obtidos, sendo analisados com relação à morfologia, por microscopia ótica, eletrônica de varredura e confocal, eficiência de encapsulação, tamanho e distribuição de tamanho de partícula e estabilidade do material encapsulado. A obtenção das microcápsulas de AA pelos dois métodos citados foi viável uma vez que apresentaram altos valores de eficiência de encapsulação e ótima atuação em relação à proteção do AA durante estocagem. Comparando-se os dois métodos, as cápsulas obtidas por dispositivos microfluídicos conferiram melhor estabilidade ao ácido ascórbico, no entanto amostras obtidas por coacervação complexa foram aplicadas em salsicha devido a maior quantidade de AA presente em sua constituição. O efeito da aplicação das microcápsulas nas salsichas foi avaliado durante 40 dias de armazenamento refrigerado como será visto no Capítulo 4. Cinco tratamentos foram elaborados e analisados de acordo com a estabilidade da emulsão cárnea durante o processamento, umidade, atividade de água, alteração do pH, determinação da cor instrumental, perfil de textura instrumental, estabilidade oxidativa pelo método de substâncias reativas ao ácido tiobarbitúrico (TBARS) e aceitação sensorial. A aplicação das microcápsulas de AA em salsicha foi possível sem comprometer a qualidade do produto final. Todos os dados obtidos foram analisados estatisticamente por análise de variância ANOVA e teste de Tukey, ao nível de 5% de significância com auxílio do programa SAS. Os experimentos relacionados à encapsulação por coacervação complexa e aplicação das microcápsulas em salsicha foram realizados no Laboratório de Produtos Funcionais, nas dependências do Departamento de Engenharia de Alimentos da FZEA/USP. Os experimentos relacionados à utilização de dispositivos microfluídicos foram realizados nos laboratórios do professor David A. Weitz, da Escola de Engenharia e Ciências Aplicadas de Harvard, da Universidade de Harvard, Cambridge, Estados Unidos.
Lipid oxidation reactions are responsible for the development of unpleasant tastes and odors making food unfit for consumption. For this reason, the use of antioxidant is necessary. Ascorbic acid (AA) is a very effective antioxidant with vitamin function, however it is relatively unstable. With the aim of increasing the stability of AA and thus improve its application in food products, the methods of encapsulation by complex coacervation and microfluidic devices were tested. First of all the Literature Review is presented in Chapter 1. The encapsulation by complex coacervation can be seen in Chapter 2. For this methodology, nine treatments were obtained using gelatin and gum Arabic as encapsulant agent and analyzed regarding to morphology by optical and scanning electron microscopy, moisture, water activity, hygroscopicity, solubility, Zeta Potential, Fourier transform infrared Spectroscopy (FTIR), particle size and particle size distribution, instrumental color, encapsulation efficiency and stability of the encapsulated material. The results obtained for AA encapsulation by microfluidic device will be presented in Chapter 3. Five treatments were obtained and analyzed regarding to morphology by optical, scanning electron and confocal microscopy, encapsulation efficiency, particle size and particle size distribution and stability of the encapsulated material. The production of AA microcapsules by the two methods mentioned was feasible once that showed high levels of encapsulation efficiency and optimal performance regarding to the protection of AA during storage. Comparing the two methods, the microcapsules obtained by microfluidic device conferred better stability to AA, however samples obtained by complex coacervation were applied in sausage due to the greater amount of AA in its constitution. The effect of the application of microcapsules in sausages was evaluated during 40 days at refrigerated storage as it will be seen in Chapter 4. Five treatments were prepared and analyzed according to the stability of the meat emulsion during processing, moisture, water activity, pH changes, determination of instrumental color, instrumental texture profile, oxidative stability by the method of thiobarbituric acid reactive substances (TBARS) and sensory acceptance. The application of AA microcapsules in sausage was possible without compromising the quality of the final product. All data were statistically analyzed by ANOVA and Tukey test, at 5% of significance with the use of SAS software. The experiments related to encapsulation by complex coacervation and application of microcapsules in sausage were carried out at Laboratory of Functional Products, at Department of Food Engineering, FZEA / USP. The experiments related to the use of microfluidic devices were performed in the laboratories of Professor David A. Weitz, at School of Engineering and Applied Sciences of Harvard, at Harvard University, Cambridge, USA.
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Ferreira, Rafael de Queiroz. "Desenvolvimento e aplicação de um novo ensaio para a determinação eletroquímica da capacidade antioxidante de compostos modelo e de matrizes complexas." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/75/75132/tde-26082009-111616/.

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Este trabalho descreve o desenvolvimento e aplicações práticas de uma nova e simples metodologia eletroquímica para a determinação da capacidade antioxidante de moléculas modelo específicas e/ou algumas amostras complexas de alimentos normalmente consumidas no Brasil. Outros sistemas de interesse teórico ou tecnológico também foram investigados. O método se baseia no uso de uma quantidade conhecida de um íon inorgânico como oxidante e na determinação cronoamperométrica de sua concentração remanescente após reação com as espécies antioxidantes de interesse. Contudo, testes iniciais para diferentes marcas comerciais de sucos de laranjas usando Fe3+ como oxidante (ensaio FRAP modificado), só obtiveram êxito quando o antioxidante apresenta um comportamento eletroquímico totalmente irreversível como, por exemplo, o ácido ascórbico. Para superar esse problema, o ensaio foi então desenvolvido usando o Ce4+ como oxidante (ensaio CRAC) uma vez que sua redução após reação pode ser realizada em 0,8 V vs Ag/AgCl, uma região de potencial na qual não ocorre a redução das espécies formadas pela oxidação reversível ou quase reversível do antioxidante. Devido ao elevado potencial anódico requerido quando o Ce4+ é usado, foi necessário um filme de diamante dopado com boro como eletrodo de trabalho. Após uma rigorosa caracterização do sistema eletroquímico, foram realizadas determinações da capacidade antioxidante de oito compostos padrões (ácido ascórbico, ácido gálico, ácido tânico, BHA, catequina, quercetina, rutina e trolox), usando o ensaio CRAC. Os resultados mostraram uma correlação satisfatória com ensaios mais complexos reportados na literatura e foram aplicados em um conjunto de sucos de frutas industrializados, mostrando valores máximos com quase uma ordem de grandeza superior ao apresentado pelo composto de referência (trolox), com a seguinte seqüência de capacidade antioxidante: caju > goiaba > uva > manga > laranja > maracujá. Considerando a busca da indústria local de \"cachaça\" por madeiras alternativas em contrapartida aos tonéis de carvalho, o ensaio CRAC foi realizado usando quatro extratos etanólicos de madeiras brasileiras [Pequi (Caryocar brasiliense), Imbuia (Octea porosa), Cabreúva (Myrocarpus frondosus) e Cabreúva-vermelha (Myroxylon balsamum)] assim como um extrato de Carvalho (Quercus sp), para comparação. Os resultados indicaram um aumento na capacidade antioxidante na ordem apresentada acima e, apesar da melhor amostra (Cabreúva-vermelha) ter apenas 60% da capacidade antioxidante apresentada pelo carvalho, sua disponibilidade e preço despertam o interesse por pesquisas futuras. Uma avaliação comparativa dos resultados obtidos usando os ensaios CRAC e DPPH foi realizado para extratos metanólicos de cana-de-açúcar e polpa de maracujá. Essa comparação revelou uma diferença quantitativa entre os valores dos ensaios, porém, a hierarquia foi mantida para cada conjunto de resultado. Esse efeito foi atribuído às diferenças nos mecanismos dominantes para a desativação radicalar, bem como para as condições experimentais de cada ensaio. A correlação entre a estrutura e a atividade antioxidante de moléculas modelo de flavonóides sob investigação foi relatada devido à presença de certos grupos substituintes na estrutura de difenilpirano. A atividade hierárquica para tais grupos foi estabelecida como: OH(C2´C4´) > OH(C4´) ~ OH(C3´C4´) > C2=C3 + 4-oxo > OH(C3,C5) + 4-oxo > OH(C3) + 4-oxo > OH(C5) + 4-oxo > OH(C3,C5). A formação de complexos entre flavonóides e íons metálicos, tal como o Fe2+, tem um forte efeito sobre a capacidade antioxidante e o ensaio CRAC mostrou que para a morina, quercetina e fisetina, esse aumento foi de 15,3; 31,8 e 27,9%, respectivamente. Por outro lado, para a catequina e crisina, o aumento foi de apenas 1,8 e 7,8%, respectivamente. Esses aumentos foram relatados devido à presença de, pelo menos, um dos três tipos de sítios ativos na molécula polifenólica que interage com íons metálicos. Todos esses resultados confirmam que o ensaio CRAC é uma ferramenta simples e viável para a determinação da capacidade antioxidante de uma variedade de sistemas práticos e moléculas modelo.
This work describes the development and practical applications of a novel and simple electrochemical methodology for the determination of the antioxidant capacity of specific model molecules and/or some complex food samples currently consumed in Brazil. Other systems having either theoretical or technological interest were also investigated. The method is based on the use of a known amount of an inorganic ion as the oxidant and in the chronoamperometric determination of its remaining concentration after reaction with the chosen antioxidant species. However, initial tests for different commercial brands of orange juices using Fe3+ as the oxidant (modified FRAP assay) were only successful when the antioxidant has a totally irreversible electrochemical behavior as, for example, ascorbic acid. To overcome this problem, the assays were then performed using Ce4+ as the oxidant (the CRAC assay) since its reduction after reaction can be carried out at 0.8 V vs Ag/AgCl, a potential region where the reduction of species formed by the reversible or quasi-reversible oxidation of the antioxidant does not occur. Due to the high anodic potentials required when using Ce4+, it was necessary to have a boron-doped diamond film as the working electrode. After a rigorous characterization of the electrochemical systems, measurements of the antioxidant capacity of eight standard compounds (ascorbic acid, gallic acid, tannic acid, BHA, catechin, quercetin, rutin and trolox) were carried out using the CRAC assay. The results showed a satisfactory correlation with those reported in the literature using other more complex assays and these studies were then applied to a set of industrialized fruit juices showing maximum values almost one order of magnitude higher than that of the reference compound (trolox) and following the antioxidant capacity sequence: cashew>guava>grape>mango>orange>passion fruit. Considering that the local \"cachaça\" industry is looking for alternative woods to the use of oak barrels, CRAC assays were carried out using four ethanol extracts of Brazilian woods [Pequi (Caryocar brasiliense), Imbuia (Octea porosa), Cabreúva (Myrocarpus frondosus) e Cabreúva-vermelha (Myroxylon balsamum)] as well as an Oak (Quercus sp) extract, for comparison. The results indicate an increasing antioxidant capacity in the order presented above and, although the best sample (Cabreúva-vermelha) has only 60% of the capacity shown by oak, its local availability and price makes it interesting for further research. A comparative evaluation of the results obtained using the CRAC and the DPPH assays was carried out for methanol extracts of sugar cane juice and passion fruit pulp. That comparison revealed a quantitative difference between the assay values but the hierarchy was maintained for each set of results. Such effect was attributed to differences in the prevailing mechanism for radical deactivation, as well as, the experimental conditions used for each assay. The correlation between structure and antioxidant activity of model flavonoid molecules under investigation was related to the presence of certain groups in the diphenilpyrene structure. The activity hierarchy for them was established as: OH(C2´C4´) > OH(C4´) ~ OH(C3´C4´) > C2=C3 + 4-oxo > OH(C3,C5) + 4-oxo > OH(C3) + 4-oxo > OH(C5) + 4-oxo > OH(C3,C5). The complex formation between flavonoids and metal ions, such as Fe2+, has a strong effect on the antioxidant capacity and CRAC assay showed that for morin, quercetin and fisetin the increase was 15.3, 31.8 and 27.9%, respectively. On the other hand, for catechin and chrysin the increase was only 1.8 and 7.8%, respectively. These increases were related to the presence of, at least, one of three types of active sites in the polyphenolic molecule that can interact with metal ions. All these findings confirm that the CRAC assay is simple and convenient tool for the determination of the antioxidant capacity of a variety of practical systems and model molecules.
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Книги з теми "Complex antioxidant"

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Kovtun, G. A. Metallokompleksnye ingibitory okislenii͡a︡. Kiev: Nauk. dumka, 1993.

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Morais, Selene Maia de, and Ícaro Gusmão Pinto Vieira. Introdução à Prospecção de Produtos Naturais. Editora Poisson, 2021. http://dx.doi.org/10.36229/978-65-5866-110-8.

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A prospecção de produtos naturais de plantas se faz através de metodologias que estão inseridas na linha de estudo denominada fitoquímica, essencial para o seu aproveitamento. A investigação de substâncias presentes em plantas e outros organismos vivos exige o desenvolvimento de procedimentos padronizados para a preparação de extratos de forma reprodutível e eficiente e a determinação da sua composição química. As principais técnicas envolvidas nesta investigação constituem as metodologias como cromatografia em fase gasosa (CG), cromatografia líquida de alta eficiência (CLAE), cromatografia em camada delgada (CCD) e técnicas de fracionamento de extratos de composição complexa. Este livro está dividido em sete capítulos em que será feita a apresentação dos diversos tipos de metabólitos secundários presentes em plantas, preparação de extratos das várias partes das plantas por diversas metodologias, isolamento e caracterização destes constituintes por métodos cromatográficos de análise, testes fitoquímicos, utilizando reagentes específicos com formação de precipitados ou mudança de coloração para a caracterização das principais classes de compostos e testes espectrofotométricos para prospecção de compostos fenólicos e determinação de suas atividades antioxidantes. Os vários métodos de extração e de cromatografia permitem o desenvolvimento do estudo de extratos de plantas, resultando o acesso a substâncias importantes como os compostos denominados de flavonoídes, alcaloides, acetogeninas, terpenoides, taninos, polissacarídeos, lipídeos, dentre outros. Este livro foi elaborado inicialmente para consulta na disciplina de Química de Produtos Naturais ministrada no Curso de Química, bem como nas disciplinas de Prospecção de Recursos Naturais do Programa de Pós-graduação em Ciências Naturais e da disciplina Processos de Extração, Purificação e Quantificação de Produtos Naturais do Doutorado em Biotecnologia da RENORBIO da Universidade Estadual do Ceará.
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Peña, Aris Verdecia. Tópicos nas Ciências da Saúde Volume III. Pantanal Editora, 2020. http://dx.doi.org/10.46420/9786588319253.

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A Editora Pantanal em seu 3º Volume do E-book “Tópicos nas ciências da saúde”, com seis capítulos traz novos temas no atuar da medicina. A obra, vem a materializar o anseio da Editora Pantanal na divulgação de resultados, que contribuem de modo direto no desenvolvimento e saúde humana. No primeiro capitulo o trabalho nos apresenta uma patologia que, embora muitos pensem que não é comum, tem grande impacto em nossa população mundial. A frequência desta patologia na década de 80 - 90 foi de 2 - 4 x 10.000 habitantes, porém com estudos atuais e levando em consideração não apenas o transtorno autista, mas todos os transtornos generalizados do desenvolvimento ou TEA (sigla em inglês), nesse novo cenário as estimativas aumentam de 21 para 35 x 10.000 habitantes. Com uma intervenção comportamental intensiva precoce, terapia cognitivo-confuctual e treinamento em habilidades sociais, obteve-se que em alguns casos leves os sintomas desaparecem, razão pela qual o diagnóstico precoce e o apoio incondicional da família são necessários; tudo isso refletido em nosso primeiro tópico. Em seguida, nosso pequeno volume faz uma incursão no campo das vitaminas que, como muitos estudiosos sabem, há um total de 13 vitaminas classificadas em dois grupos, solúveis em água (8 do complexo B e vitamina C) e quatro solúveis em gordura; A; D; E e K, que desempenham um papel fundamental no nosso organismo porque participam nos processos e reações que nele ocorrem e é importante não só tomá-los na forma de comprimidos, mas também incorporá-los através de uma alimentação equilibrada, saudável e saudável, para mim sobretudo a fonte da juventude porque atrasa o envelhecimento devido à sua ação antioxidante, aqui mostramos vários deles nas suas diferentes funções. Por fim, encerramos nosso livro com a apresentação de um caso onde mostramos que não é importante apenas tratar o somático, mas fazer um diagnóstico psicossocial do indivíduo se quisermos obter bons resultados em nossa prática profissional. Agradecemos aos autores pela dedicação e os encorajamos a continuar colaborando em nosso projeto. Aos autores dos capítulos, pela dedicação e esforços sem limites, que viabilizaram esta obra que retrata os recentes avanços científicos e tecnológicos na área de Ciências da Saúde, os agradecimentos da Organizadora e da Pantanal Editora. Por fim, esperamos que este e-book possa colaborar e instigar mais estudantes e pesquisadores na constante busca de novas tecnologias e avanços para a medicina. Assim, garantir uma difusão de conhecimento fácil, rápido para a sociedade. Aris Verdecia Peña
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Частини книг з теми "Complex antioxidant"

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Carini, R., A. Comoglio, H. Basaga, E. Albano, and G. Poli. "Antioxidant and Hepatoprotective Properties of IdB 1016, A New Flavanolignan Complex." In Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury, 111–13. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-3520-1_25.

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Ali, Mamdouh M. "Germanium l-Cysteine Alpha-Tocopherol Complex as Stimulator to Antioxidant Defense System." In Encyclopedia of Metalloproteins, 836–41. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-1533-6_125.

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Laguta, I. V., P. O. Kuzema, O. N. Stavinskaya, and O. A. Kazakova. "Supramolecular Complex Antioxidant Consisting of Vitamins C, E and Hydrophilic–Hydrophobic Silica Nanoparticles." In Nanomaterials and Supramolecular Structures, 269–79. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-2309-4_22.

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Riedl, Ken M., Stephane Carando, Helaine M. Alessio, Mark McCarthy, and Ann E. Hagerman. "Antioxidant Activity of Tannins and Tannin-Protein Complexes: Assessment In Vitro and In Vivo." In ACS Symposium Series, 188–200. Washington, DC: American Chemical Society, 2002. http://dx.doi.org/10.1021/bk-2002-0807.ch014.

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Doctrow, Susan R., Michel Baudry, Karl Huffman, Bernard Malfroy, and Simon Melov. "Salen Manganese Complexes: Multifunctional Catalytic Antioxidants Protective in Models for Neurodegenerative Diseases of Aging." In ACS Symposium Series, 319–47. Washington, DC: American Chemical Society, 2005. http://dx.doi.org/10.1021/bk-2005-0903.ch018.

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Kanarovskii, E. Yu, O. V. Yaltychenko, and N. N. Gorinchoy. "Theoretical Model of Lipid Peroxidation Kinetics for Complexes of Cytochrome c and Cardiolipin with Participation of Antioxidants." In IFMBE Proceedings, 561–65. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-31866-6_100.

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Geras'kin, Stanislav, Roman Churyukin, Polina Volkova, and Sofiya Bitarishvili. "Using ionizing radiation for improving the development and yield of agricultural crops." In Mutation breeding, genetic diversity and crop adaptation to climate change, 424–32. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789249095.0043.

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Abstract The response of barley seedlings was studied after gamma irradiation of seeds with doses in the range of 2-50 Gy. It was shown that stimulation of plant growth occurred in the dose range of 16-20 Gy. The influences of the dose rate, the quality of seeds and their moisture on the manifestation of radiation effects were investigated. We studied, under controlled conditions, the activities of metabolic and antioxidant enzymes and observed an increase in their activity in the range of doses that cause stimulation of seedling growth. We showed that changes in the balance among different classes of phytohormones were probably involved in the acceleration of plant growth after irradiation of seeds using stimulating doses. Gamma irradiation of barley seeds significantly influenced the development of plants during the growing season. After irradiation with stimulating doses, we observed a reduction in the duration of the initial stages of ontogenesis; the phase of full ripeness occurred 5-7 days earlier than in the controls. The manifestation of the effect of irradiation depended on the conditions in which the plants developed. During the growing season of 2014, which was a dry year, plants originating from the irradiated seeds showed an increase in the number of productive stems, which led to an increase in yield by 34-38%; during the optimal 2015 season, an increase in the number of grains per spike caused an increase in yield by 8-29%. Therefore, our field study has shown that at least some hormetic effects can occur in the field. Irradiation of seeds can increase field germination, stimulate the growth and development of plants and increase their resistance to unfavourable environmental conditions. A more complete understanding of the underlying mechanisms of hormesis is needed to exploit its potential benefits in crop production.
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"Germanium Complex as Antioxidant." In Encyclopedia of Metalloproteins, 836. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-1533-6_100541.

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Sen, Saikat, and Raja Chakraborty. "Food in Health Preservation and Promotion." In Food Science and Nutrition, 392–426. IGI Global, 2018. http://dx.doi.org/10.4018/978-1-5225-5207-9.ch017.

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Association between food and health is complex. Healthy food can promote and maintain good human health. Healthy food and nutrition is a key regulating factor for boosting the immunity and therapeutic effectiveness of a treatment strategy. Oxidative stress is well involved in the pathogenesis of diverse diseases and aging. Food always considered as good source of nutrients, protein, fat, carbohydrates, vitamins, minerals and antioxidants. Consumed as part of a normal diet, phytochemicals present in food like vitamins (vitamin C & E), minerals (like, zinc, selenium), phytoconstituents (phenolic compounds, flavonoids, carotenoids) confer additional health benefits, by virtue of their antioxidant property. A diet rich that rich in antioxidant molecule reduces the risk of several oxidative stress related diseases. Numerous antioxidant molecules isolated from food showed the curative and health promotion effect. This chapter majorly deals with the role antioxidant/pro-oxidant substances present in different foods on human body.
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Sen, Saikat, and Raja Chakraborty. "Food in Health Preservation and Promotion." In Advances in Environmental Engineering and Green Technologies, 265–300. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-0591-4.ch013.

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Association between food and health is complex. Healthy food can promote and maintain good human health. Healthy food and nutrition is a key regulating factor for boosting the immunity and therapeutic effectiveness of a treatment strategy. Oxidative stress is well involved in the pathogenesis of diverse diseases and aging. Food always considered as good source of nutrients, protein, fat, carbohydrates, vitamins, minerals and antioxidants. Consumed as part of a normal diet, phytochemicals present in food like vitamins (vitamin C & E), minerals (like, zinc, selenium), phytoconstituents (phenolic compounds, flavonoids, carotenoids) confer additional health benefits, by virtue of their antioxidant property. A diet rich that rich in antioxidant molecule reduces the risk of several oxidative stress related diseases. Numerous antioxidant molecules isolated from food showed the curative and health promotion effect. This chapter majorly deals with the role antioxidant/pro-oxidant substances present in different foods on human body.
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Тези доповідей конференцій з теми "Complex antioxidant"

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Hu, Jian-Qiang, Xian-Yong Wei, Yan Fu, and Jun-Bing Yao. "Study on Synergistic Antioxidance Properties of Organic Molybdenum Complex With Arylamine Antioxidant." In STLE/ASME 2006 International Joint Tribology Conference. ASME, 2006. http://dx.doi.org/10.1115/ijtc2006-12021.

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Zhang, Yi, Yan Luo, Jian-Qiang Hu, Tao Zhang, and Yun-Yun Xu. "Study on Antioxidation Properties of the Complex of Dithiocarbamate With Tolutriazole Antioxidant." In ASME/STLE 2007 International Joint Tribology Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/ijtc2007-44020.

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The antioxidation properties of methylene bis(di-n-butyldithiocarbamate) (V 7723) - and tolutriazole derivative (V 887) - containing poly-a-olefin (PAO)-derived lubricants were evaluated by differential scanning calorimetry (DSC) and modified penn state micro-oxidation test (PMOT). DSC test measures incipient oxidation temperature (OT) and oxidation induction time (IT) of the lubricant at high temperatures and the oxidation stability of oil weight loss is measured by PMOT test. DSC test shows that OT and IT of V 7723-containing PAO were improved significantly by V 887 addition. PMOT test indicates that when combining with V 7723 antioxidants, V 887 can also effectively reduce the increase in weight loss of PAO. In addition, FTIR results from PMOT test confirm that addition of V 887 can significantly enhance the oxidation induction time of oils. These results suggest that the V 7723 shows a good oxidative synergism with V 887 antioxidant.
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LI, Qiang-Guo, Wei ZHENG, and Si-Zhu WU. "The Antioxidant Effect of Lanthanum Complex in Natural Rubber." In 3rd International Conference on Material Engineering and Application (ICMEA 2016). Paris, France: Atlantis Press, 2016. http://dx.doi.org/10.2991/icmea-16.2016.30.

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Belov, V. P., and E. A. Vinokurova. "Perioperative period in the radical treatment of uterine cancer: features of management." In Наука России: Цели и задачи. НИЦ "LJournal", 2021. http://dx.doi.org/10.18411/sr-10-08-2021-06.

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Purpose of the study is to characterize the state of coagulation and state of lipid peroxidation and antioxidant potential in cases of women with uterine cancer during surgery, to evaluate the effectiveness of the of antioxidants used in order to correct changes in the hemostatic system. 104 women were examined. Women were separated into 3 groups: healthy, receiving standard therapy and standard therapy + selmevitum. the patients showed a change in hemostasis which was mostly prevented by using additional vitamin and mineral complex – selmevitum before and after operation.
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Shamray, Lev V. "Antioxidant Agents In Complex Pre-Competition Training Of Boxer Students." In 18th PCSF 2018 - Professional Сulture of the Specialist of the Future. Cognitive-Crcs, 2018. http://dx.doi.org/10.15405/epsbs.2018.12.02.116.

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Jin, Liming, Fangning Guo, Ai-Li Jiang, and Wenzhong Hu. "Preparation and Antioxidant Activity of Lycium barbarum Polysaccharide Iron Complex." In 2015 3rd International Conference on Advances in Energy and Environmental Science. Paris, France: Atlantis Press, 2015. http://dx.doi.org/10.2991/icaees-15.2015.175.

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Khalid Saeed, M., Z. Iqbal, S. Mehmud, N. Ejaz, and Waqar-u-Nisa. "Antioxidant activity of Zingiber officinale Roscoe's extract, oleoresin and essential oil from Pakistan." In 2009 IEEE/ICME International Conference on Complex Medical Engineering - CME 2009. IEEE, 2009. http://dx.doi.org/10.1109/iccme.2009.4906679.

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Jianqiang, Hu, Peng Zhuliang, Ji Feng, and Hu Jianqiang. "Evaluation of Organic molybdenum Complex as a Synergist for Arylamine Antioxidant in Synthetic Lubricants." In Powertrain & Fluid Systems Conference & Exhibition. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2005. http://dx.doi.org/10.4271/2005-01-3824.

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Fedorova, A. M. "Obtaining an antioxidant complex of bas extracted from Thymus Vulgaris L. and Panax Ginseng S.A. Meu." In Agrobiotechnology-2021. Publishing house RGAU-MSHA, 2021. http://dx.doi.org/10.26897/978-5-9675-1855-3-2021-129.

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The article presents a chromatographic study of a complex of BAS obtained by water-alcohol extraction of medicinal plants of the Siberian Federal District. Medicinal plants Thymus vulgaris D. and Panax ginseng S.A. Menu were selected as BAS analysis
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Tomenko, D., E. Aksenov, and Lyudmila Novikova. "PHENOLIC COMPOUNDS OF CONIFEROUS TREES." In Modern machines, equipment and IT solutions for industrial complex: theory and practice. FSBE Institution of Higher Education Voronezh State University of Forestry and Technologies named after G.F. Morozov, 2021. http://dx.doi.org/10.34220/mmeitsic2021_351-356.

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The paper discusses the classification, structure and properties of natural phenolic compounds found in conifers wood species of Russia. The reasons for the variety of detected phenolic compounds (more than 2000) are considered, including the type and conditions of plant growth, environmental factors, as well as methods for extraction of substances. Coniferous extractives include monomeric, dimeric and polymeric phenolic compounds in bound and free form, and their content differs significantly for various species and parts of a woody plant. Depending on the polarity of the solvent used (water, petroleum ether, dimethyl ether, ethyl acetate, acetone, etc.), the yield, chemical composition and structure of the extracted phenolic compound change. It was shown that bark extracts of Larch and Fir contain the most phenolic acids and extractive substances than Pine, Cedar and Spruce, while the content of polar substances is higher in needles, and non- polar substances in plant shoots. Phenolic compounds are secondary plant metabolites, exhibiting fungicidal, virucidal and strong antioxidant effects, that make them a valuable basis for the creation of drugs.
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Звіти організацій з теми "Complex antioxidant"

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Poltavtsev, A. M., and E. I. Zaraisky. Assessment of the quality and biosafety of Shogaol nanoparticles in ginger, used in complex oncotherapy as an antioxidant. Sputnik+, 2018. http://dx.doi.org/10.18411/nts_2018n10.

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Kanner, Joseph, Edwin Frankel, Stella Harel, and Bruce German. Grapes, Wines and By-products as Potential Sources of Antioxidants. United States Department of Agriculture, January 1995. http://dx.doi.org/10.32747/1995.7568767.bard.

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Several grape varieties and red wines were found to contain large concentration of phenolic compounds which work as antioxidant in-vitro and in-vivo. Wastes from wine production contain antioxidants in large amounts, between 2-6% on dry material basis. Red wines but also white wines were found to prevent lipid peroxidation of turkey muscle tissues stored at 5oC. The antioxidant reaction of flavonoids found in red wines against lipid peroxidation were found to depend on the structure of the molecule. Red wine flavonoids containing an orthodihydroxy structure around the B ring were found highly active against LDL and membrane lipid peroxidation. The antioxidant activity of red wine polyphenols were also found to be dependent on the catalyzer used. In the presence of H2O2-activated myoglobin, the inhibition efficiency was malvidin 3-glucoside>catechin>malvidin>resveratol. However, in the presence of an iron redox cycle catalyzer, the order of effectiveness was resveratol>malvidin 3-glucoside = malvidin>catechin. Differences in protein binding were found to affect antioxidant activity in inhibiting LDL oxidation. A model protein such as BSA, was investigated on the antioxidant activity of phenolic compounds, grape extracts, and red wines in a lecithin-liposome model system. Ferulic acid followed by malvidin and rutin were the most efficient in inhibiting both lipid and protein oxidation. Catechin, a flavonal found in red-wines in relatively high concentration was found to inhibit myoglobin catalyzed linoleate membrane lipid peroxidation at a relatively very low concentration. This effect was studied by the determination of the by-products generated from linoleate during oxidation. The study showed that hydroperoxides are catalytically broken down, not to an alcohol but most probably to a non-radical adduct. The ability of wine-phenolics to reduce iron and from complexes with metals were also demonstrated. Low concentration of wine phenolics were found to inhibit lipoxygenase type II activity. An attempt to understand the bioavailability in humans of antocyanins from red wine showed that two antocyanins from red wine were found unchanged in human urine. Other antocyanins seems to undergo molecular modification. In hypercholesterolemic hamsters, aortic lipid deposition was significantly less in animals fed diets supplemented with either catechin or vitamin E. The rate of LDL accumulation in the carotid arteries was also significantly lower in the catechin and vitamin E animal groups. These results suggested a novel mechanism by which wine phenolics are associated with decreased risk of coronary heart diseases. This study proves in part our hypothesis that the "French Paradox" could be explained by the action of the antioxidant effects of phenolic compounds found at high concentration in red wines. The results of this study argue that it is in the interest of public health to increase the consumption of dietary plant falvonoids. Our results and these from others, show that the consumption of red wine or plant derived polyphenolics can change the antioxidant tone of animal and human plasma and its isolated components towards oxidative reactions. However, we need more research to better understand bioavailability and the mechanism of how polyphenolics affect health and disease.
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Pell, Eva J., Sarah M. Assmann, Amnon Schwartz, and Hava Steinberger. Ozone Altered Stomatal/Guard Cell Function: Whole Plant and Single Cell Analysis. United States Department of Agriculture, December 2000. http://dx.doi.org/10.32747/2000.7573082.bard.

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Original objectives (revisions from original proposal are highlighted) 1. Elucidate the direct effects O3 and H2O2 on guard cell function, utilizing assays of stomatal response in isolated epidermal peels and whole cell gas exchange. 2. Determine the mechanistic basis of O3 and H2O2 effects on the plasma membrane through application of the electrophysiological technique of patch clamping to isolated guard cells. 3. Determine the relative sensitivity of Israeli cultivars of economically important crops to O3 and determine whether differential leaf conductance responses to O3 can explain relative sensitivity to the air pollutant: transfer of technological expertise to Israel. Background to the topic For a long time O3 has been known to reduce gas exchange in plants; it has however been unclear if O3 can affect the stomatal complex directly. Ion channels are essential in stomatal regulation, but O3 has never before been shown to affect these directly. Major conclusions, solution, achievements 1. Ozone inhibits light-induced stomatal opening in epidermal peels isolated from Vicia faba, Arabidopsis thaliana and Nicotiana tabacum in V. faba plants this leads to reduced assimilation without a direct effect on the photosynthetic apparatus. Stomatal opening is more sensitive to O3 than stomatal closure. 2. Ozone causes inhibition of inward K+ channels (involved in stomatal opening) while no detectable effect is observed o the outward K+ channels (stomatal closure). 3. Hydrogen peroxide inhibits stomatal opening and induces stomatal closure in epidermal peels isolated from Vicia faba. 4. Hydrogen peroxide enhances stomatal closure by increasing K+ efflux from guard cells via outward rectifying K+ channels. 5. Based on epidermal peel experiments we have indirectly shown that Ca2+ may play a role in the guard cell response to O3. However, direct measurement of the guard cell [Ca2+]cyt did not show a response to O3. 6. Three Israeli cultivars of zucchini, Clarita, Yarden and Bareqet, were shown to be relatively sensitive to O3 (0.12 ml1-1 ). 7. Two environmentally important Israeli pine species are adversely affected by O3, even at 0.050 ml1-1 , a level frequently exceeded under local tropospheric conditions. P. brutia may be better equipped than P. halepensis to tolerate O3 stress. 8. Ozone directly affects pigment biosynthesis in pine seedlings, as well as the metabolism of O5 precursors, thus affecting the allocation of resources among various metabolic pathways. 9. Ozone induces activity of antioxidant enzymes, and of ascorbate content i the mesophyll and epidermis cells of Commelina communis L. Implications, both scientific and agricultural We have improved the understanding of how O3 and H2O2 do affect guard cell and stomatal function. We have shown that economical important Israeli species like zucchini and pine are relatively sensitive to O3.
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