Добірка наукової літератури з теми "Compétence pour la transformation par l'ADN"
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Статті в журналах з теми "Compétence pour la transformation par l'ADN":
Terré, Nicolas, Carole Sève, and Jacques Saury. "Une approche énactive du développement des compétences en milieu scolaire." Éducation et francophonie 44, no. 2 (February 20, 2017): 68–85. http://dx.doi.org/10.7202/1039022ar.
Lacasse, Miriam, Jean-Sébastien Renaud, Adrien Cantat, and Danielle Saucier. "Développement de compétences avancées dans la formation des futurs médecins : l’exemple de la médecine familiale au Canada." Éducation et francophonie 44, no. 2 (February 20, 2017): 126–51. http://dx.doi.org/10.7202/1039025ar.
Mili, Abdesselam. "La formation des enseignants et transformation des pratiques d'enseignement." Journal of Quality in Education 4, no. 5 (May 5, 2014): 17. http://dx.doi.org/10.37870/joqie.v4i5.57.
Otis, Ghislain. "La production du droit autochtone : comportement, commandement, enseignement." État et cultures juridiques autochtones : un droit en quête de légitimité 48, no. 1 (July 9, 2018): 67–89. http://dx.doi.org/10.7202/1049314ar.
Sheptycki, James. "The Accountability of Transnational Policing Institutions: The Strange Case of Interpol." Canadian journal of law and society 19, no. 1 (April 2004): 107–34. http://dx.doi.org/10.1017/s0829320100007973.
Vicente, Michaël. "La Grande École du Numérique : les paradoxes d’une politique de promotion des formations techniques centrées sur l’apprentissage du code informatique." Lien social et Politiques, no. 81 (February 19, 2019): 212–29. http://dx.doi.org/10.7202/1056312ar.
Jaubert, Martine, and Maryse Rebière. "Quels outils pour rendre compte du passage d’une langue quotidienne à une langue disciplinaire scolaire ?" Swiss Journal of Educational Research 42, no. 3 (December 23, 2020): 569–81. http://dx.doi.org/10.24452/sjer.42.3.4.
Namaste, Nina B. "Designing and Evaluating Students' Transformative Learning." Canadian Journal for the Scholarship of Teaching and Learning 8, no. 3 (December 4, 2017). http://dx.doi.org/10.5206/cjsotl-rcacea.2017.3.5.
Zerbib, romain, and romain zerbib. "LA TRANSFORMATION NUMÉRIQUE VA T-ELLE NOUS RENDRE OBSOLÈTES ?" Management & Data Science, 2023. http://dx.doi.org/10.36863/mds.a.25444.
Đurić, Ljiljana. "L’ŒUVRE LITTÉRAIRE AU CENTRE DE LA MÉDIATION LINGUISTIQUE AU NIVEAU UNIVERSITAIRE : REGARDS CROISÉS." Facta Universitatis, Series: Linguistics and Literature, January 6, 2020, 263. http://dx.doi.org/10.22190/full1902263d.
Дисертації з теми "Compétence pour la transformation par l'ADN":
Juillot, Dimitri. "Etude du mécanisme de l'arrêt de division pendant la transformation génétique naturelle chez streptococcus pneumoniae." Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASL153.
Streptococcus pneumoniae (the pneumococcus) is a commensal bacterium that can cause pneumonia, meningitis or septicemia under certain conditions. Control of pneumococcal infections is based on the use of antibiotics or vaccines. However, both of these approaches come up against the pneumococcus remarkable potential for genetic plasticity, which depends on its ability to uptake exogenous DNA through transformation. Transformation is a highly conserved DNA exchange mechanism in bacteria that contributes to their diversification, evolution and adaptation. The ability of bacteria to transform requires the development of a specific physiological state called 'competence'. In the pneumococcus, competence develops transiently in all cells of the population during their multiplication phase. It is accompanied by an arrest of the division process, which allows the cells to complete the final stages of transformation without compromising the integrity of their genome. ComM, a protein of unknown function synthesized during competence, appears necessary and sufficient to induce this inhibition of cell division. The goal of this PhD project was to decipher the mechanism of action of ComM. To measure the impact of ComM, and more generally the development of competence, on the dynamics of cell division proteins, I used total internal reflection fluorescence (TIRF) microscopy. Another strategy was to identify potential interactions between transformation and division proteins, using a yeast two-hybrid approach. My results show that the development of competence interferes with the mobility of the two key proteins of the septal peptidoglycan synthesizing machinery FtsW and PBP2x. Furthermore, two-hybrid experiments revealed several interactions between ComM and division proteins, in particular the MurA1 protein, involved in the synthesis of the precursor of the PG. On the basis of my results, I propose a model in which ComM could modulate MurA1 activity to decrease the septal PG synthesis. Ultimately, this project could inspire new strategies to block the growth of the pneumococcus and thus fight against this major human pathogen