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1
Clark, David A. Cognitive-Behavioral Therapy for OCD and Its Subtypes, Second Edition. Guilford Publications, 2019.
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2
Cognitive-Behavioral Therapy for OCD and Its Subtypes, Second Edition. Guilford Publications, 2019.
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3
Psychosocial dimensions of learning disabilities: External validation of (1) statistically-derived psychosocial subtypes and their relations to (2) cognitive and academic functioning. 1993.
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4
Hillbrand, Marc. Homicide-Suicide. Edited by Phillip M. Kleespies. Oxford University Press, 2015. http://dx.doi.org/10.1093/oxfordhb/9780199352722.013.22.
Повний текст джерелаАнотація:
Homicide-suicide entails a homicide followed by the perpetrator’s suicide within one week. The incidence of homicide-suicide in the US was 0.23% per 100,000 in 2013 (about 5% of all US homicides). In Western Europe and other low violence countries, such as Japan, homicide-suicides make up a much higher proportion of all homicides. Subtypes are filicidal, spousal (including jealous and declining health subtypes), familial, and extrafamilial homicide-suicide. Spousal homicide-suicides are the most common, yet extrafamilial homicide-suicides receive the most media attention, despite their rarity. Related phenomena include mass murder, victim-precipitated suicide (“suicide by cop”), politically motivated homicide-suicide, and suicide in violent offenders. We review several conceptual models of the etiology of homicide-suicide, namely developmental, dynamic, biological, and cognitive models, and draw implications from the current state of knowledge about homicide-suicide.
5
Thomas, Alan, and Tom Dening. The concept of dementia. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199644957.003.0029.
Повний текст джерелаАнотація:
Recent developments have led to earlier assessment of people with cognitive impairment and earlier diagnosis of dementia. This has renewed discussion about the boundaries of dementia and its major causes and their relationship to ageing and also resulted in the publication of new sets of diagnostic criteria for dementia in general and the subtypes of dementia, e.g. Alzheimer’s disease. This chapter therefore consists of four contributions bringing different perspectives on the concept of dementia and its recognition and diagnosis.
6
Rubia, Katya. ADHD brain function. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198739258.003.0007.
Повний текст джерелаАнотація:
ADHD patients appear to have complex multisystem impairments in several cognitive-domain dissociated inferior, dorsolateral, and medial fronto-striato-parietal and frontocerebellar neural networks during inhibition, attention, working memory, and timing functions. There is emerging evidence for abnormalities in motivation and affect control regions, most prominently in ventral striatum, but also orbital/ventromedial frontolimbic areas. Furthermore, there is an immature interrelationship between hypoengaged task-positive cognitive control networks and a poorly ‘switched off’ default mode network, both of which impact performance. Stimulant medication enhances the activation of inferior frontostriatal systems, while atomoxetine appears to have more pronounced effects on the dorsal attention network. More studies are needed to understand the neurofunctional correlates of the effects of age, gender, ADHD subtypes, and comorbidities with other psychiatric conditions. The use of pattern recognition analyses applied to imaging to make individual diagnostic or prognostic predictions are promising and will be the challenge over the next decade.
7
Brandeis, Daniel, Sandra K. Loo, Grainne McLoughlin, Hartmut Heinrich, and Tobias Banaschewski. Neurophysiology. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198739258.003.0009.
Повний текст джерелаАнотація:
Neurophysiology allows us to understand and modulate the neural mechanisms in ADHD with high time- and/or frequency-resolution. These non-invasive methods include electroencephalographic recordings at rest and during tasks, with spontaneous and event-related oscillations and potentials tracking covert processing and transcranial neuromodulation through magnetic or electric fields. The findings indicate consistent cognitive and neural deficits in ADHD related to impaired attention and deficient inhibition. Advanced signal processing and source imaging methods often converge with other imaging approaches. Neurophysiological findings also reveal considerable heterogeneity in ADHD regarding cognitive, affective, and genetic subtypes. This illustrates the importance of dimensional approaches and of pathophysiological mechanisms partly shared with other disorders. Although several potential neurophysiological markers of ADHD have been considered, a clinical use for individual diagnostics and classification is not supported to date. More research should clarify the clinical potential of multivariate multimodal classification and prediction of treatment outcome to advance individualized treatment.
8
Stewart, S. Evelyn, and Clare Bleakley. Treatment of Pediatric OCD. Edited by Christopher Pittenger. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228163.003.0042.
Повний текст джерелаАнотація:
Appropriate OCD treatment has the potential to reverse negative impacts on the developmental trajectory of youth with this disease. First-line treatments for pediatric OCD have been well established, including cognitive behavior therapy (CBT), serotonin reuptake inhibitors (SRI), and the combination thereof. However, a significant proportion of OCD-affected youth do not achieve response or remission following initial treatment, and access to OCD-focused CBT treatment is often limited. Knowledge of CBT and SRI response predictors, mechanisms of action, and augmentation strategies for pediatric OCD should be exploited to guide individual clinical decision making. Further investigation is required to identify specific management approaches in treatment-resistant cases and putative OCD subtypes. This chapter summarizes proven first-line pharmacological and psychological treatments, discusses potential augmentation strategies, and suggests practical management tips for use in pediatric OCD.
9
Whittal, Maureen. Cognitive Therapy for OCD. Edited by Christopher Pittenger. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228163.003.0038.
Повний текст джерелаАнотація:
Cognitive treatment of obsessive compulsive disorder (OCD) offers an alternative to exposure-based treatments. This chapter explicates the theory underpinning the treatment, along with the belief domains targeted. Cognitive treatment of OCD should be seen as a modular treatment, with strategies varying according to the subtype presentations (i.e., cognitive treatment for a primary obsessional can look quite different from cognitive treatment for a doubter/checker). This chapter introduces the various treatment strategies and reviews outcome research using cognitive protocols.
10
Nuyts, Jan, and Johan Van Der Auwera, eds. The Oxford Handbook of Modality and Mood. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199591435.001.0001.
Повний текст джерелаАнотація:
This handbook offers an in depth and comprehensive state of the art survey of the linguistic domains of modality and mood and examines the full range of methodological and theoretical approaches to the phenomena involved. Following an opening section that provides an introduction and historical background to the topic, the volume is divided into five parts. Parts 1 and 2 present the basic linguistic facts about the systems of modality and mood in the languages of the world, covering the semantics and the expression of different subtypes of modality and mood respectively. The authors also examine the interaction of modality and mood, mutually and with other semantic categories such as aspect, time, negation, and evidentiality. In Part 3, authors discuss the features of the modality and mood systems in five typologically different language groups, while chapters in Part 4 deal with wider perspectives on modality and mood: diachrony, areality, first language acquisition, and sign language. Finally, Part 5 looks at how modality and mood are handled in different theoretical approaches: formal syntax, functional linguistics, cognitive linguistics and construction grammar, and formal semantics.
11
Chee, Min-Na. The performance of subtypes of learning disabled children on an inductive reasoning task. 1987.
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12
Barsky, Valerie E. The speed factor and WISC-R performance I.Q.: Effects on subtypes of learning disabled children. 1986.
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13
Steketee, Gail, and Brian H. McCorkle. Future Research on Obsessive Compulsive and Spectrum Conditions. Edited by Gail Steketee. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780195376210.013.0108.
Повний текст джерелаАнотація:
This chapter reviews comments raised by authors of 25 chapters of the Handbook of Obsessive Compulsive and Spectrum Disorders. Among the challenges raised are those within the areas of diagnosis and features of the several OC spectrum conditions, including revisions to the diagnostic nomenclature for DSM-V under consideration, especially with regard to the possible addition of hoarding disorder to distinguish this more clearly from OCD. Research on clinical versus nonclinical samples, and controversies regarding possible subtypes of OCD and of some of its spectrum conditions like BDD and hoarding, are examined. Relationships among OCD and the spectrum conditions are examined with attention to the general lack of information about this issue. Several authors in the handbook comment on personality features and their association with outcomes following treatment, with a general consensus that assessing features rather than disorders will be most useful. The impact of culture on expression of OC spectrum conditions is clearly under-studied. Causes and mechanisms underlying OCD and spectrum conditions are examined, including neurological and genetic underpinnings, information processing, beliefs and cognitive models, as well as social and familial factors. Concerns about assessment are raised with regard to OCD and its expression in older adults, in hoarding and in BDD, and the impact of culture on assessment. With regard to treatment, chapters focus on research needs concerning mechanisms of action and predictors of change, and the need to improve treatments to enhance their effects. Improvement of outcomes in a variety of areas (e.g., hoarding, children, culturally sensitive treatments) is noted, including outcomes for medications and combined CBT plus medication regimens. Special issues are raised with regard to BDD, tic disorders, and trichotillomania.
14
Harding, Kelli Jane K., and Brian A. Fallon. Somatic Symptom and Related Disorders. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199326075.003.0010.
Повний текст джерелаАнотація:
This chapter discusses the somatic symptom disorders, which are a heterogeneous group unified by physical symptoms or concerns that are associated with prominent distress or impairment. Somatic symptom disorders are estimated to account for 1 in 10 primary care patient visits. The relative prominence of somatic symptoms is essential to the difference between illness anxiety disorder, which is an example of the obsessional/cognitive subtype (not prominent) and somatic symptom disorder,, in which the somatic symptoms are prominent. Patients with body dysmorphic disorder, also an Obsessional/Cognitive subtype, are preoccupied with a perceived defect in physical appearance. Patients with conversion disorder (functional neurological symptom disorder) (dissociative sub-type) present with neurological symptoms that cannot be fully explained physiologically. Patients with factitious disorder consciously simulate illness for psychological purposes rather than practical gain.
15
Ellenstein, Aviva, Christina Prather, and Mikhail Kogan. Neurodegenerative Diseases: Parkinson’s and Alzheimer’s Diseases. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190466268.003.0020.
Повний текст джерелаАнотація:
Neurodegenerative diseases increase in prevalence with aging. This chapter begins with a discussion of Parkinson’s disease. Optimally individualized treatment includes dopaminergic medications, physiotherapy, and multidisciplinary care. Evidence for integrative approaches is limited. Advances in genetics and biomarkers hold promise for subtype-specific, precision treatment in the near future. The second part of this chapter focuses on Alzheimer’s disease. Standard evaluation includes assessment for possible contributing factors that may worsen cognition, and management includes optimizing factors that may improve cognitive function. No disease-modifying medical approaches yet exist, but increasing emphasis on interventions to limit chronic inflammation and optimize brain metabolism remain fundamental in the integrative approach to Alzheimer’s disease. The new metabolic approach first described by Dr. Dale Bredesen is summarized and the importance of multidisciplinary care, with emphasis on early transition to palliative care when appropriate, is reviewed.
16
Sprigings, David. Delirium (acute confusional state). Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0041.
Повний текст джерелаАнотація:
Delirium is a functional brain disorder characterized by disturbances of consciousness, attention, and cognition. The term ‘acute confusional state’ is often used synonymously with ‘delirium’. Delirium may be associated with a range of associated clinical features including increased or decreased psychomotor activity (hyperactive and hypoactive variants), hallucinations and delusions, and efferent sympathetic hyperactivity. Delirium with pronounced psychomotor and sympathetic hyperactivity is more often seen in younger patients with alcohol or substance intoxication/withdrawal (delirium tremens), but no cause is specific to a clinical subtype. Delirium is distinguished from dementia (with which it may coexist, as dementia is a major risk factor for delirium) by its speed of onset (over hours or days) and reversibility with correction of the underlying cause. In some patients, however, delirium may be followed by long-term cognitive impairment, suggesting that the pathophysiology of delirium overlaps with that of dementia.
17
van den Boogaard, Mark, and Paul Rood. Delirium in Critically Ill Patients. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199398690.003.0002.
Повний текст джерелаАнотація:
This chapter addresses delirium in critically ill patients in the intensive care unit (ICU), especially the mixed subtype (alternating hyperactivity and hypoactivity). The Confusion Assessment Method for the ICU and the Intensive Care Delirium Screening Checklist are discussed as useful delirium assessment tools in this setting. Several neurotransmitter pathways have been implicated in delirium, including cholinergic, GABAergic, and serotonergic pathways; cytokines and glucocorticoids also appear relevant. Risk factors for delirium in the ICU include older age, prior cognitive impairment, worse illness severity, recent delirium or coma, mechanical ventilation, admission category (especially trauma or neurological/neurosurgical admission), infection, metabolic acidosis, morphine and sedative administration, urea concentration, respiratory failure, and admission urgency. Prevention and treatment of delirium are discussed, including nonpharmacological interventions (frequent reorientation, providing eyeglasses and hearing aids if needed, promoting nighttime sleep, and early mobilization) and judicious use of opiate, sedative, and antipsychotic medications.
18
Del Giudice, Marco. Evolutionary Psychopathology. Oxford University Press, 2018. http://dx.doi.org/10.1093/med-psych/9780190246846.001.0001.
Повний текст джерелаАнотація:
This book presents a unified approach to evolutionary psychopathology, and advances an integrative framework for the analysis and classification of mental disorders based on the concepts of life history theory. The framework does not aim to replace existing evolutionary models of specific disorders—which are reviewed and critically discussed in the book—but to connect them in a broader perspective and explain the large-scale patterns of risk and comorbidity that characterize psychopathology. The life history framework permits a seamless integration of mental disorders with normative individual differences in personality and cognition, and offers new conceptual tools for the analysis of developmental, genetic, and neurobiological data. The concepts synthesized in the book are used to derive a new taxonomy of mental disorders, the fast-slow-defense (FSD) model. The FSD model is the first classification system explicitly based on evolutionary concepts, a biologically grounded alternative to transdiagnostic models based on empirical correlations between symptoms. The book reviews a wide range of common mental disorders, discusses their classification in the FSD model, and identifies functional subtypes within existing diagnostic categories.
19
Leys, Didier, Charlotte Cordonnier, and Valeria Caso. Stroke. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0067.
Повний текст джерелаАнотація:
Stroke is a major public health issue. Many are treatable in the acute stage, provided patients are admitted soon enough. The overall incidence of stroke in Western countries is approximately 2400 per year per million inhabitants, and 80% are due to cerebral ischaemia. The prevalence is approximately 12 000 per million inhabitants. Stroke is associated with increased long-term mortality, handicap, cognitive and behavioural impairments, recurrence, and an increased risk of other types of vascular events. It is of major interest to take the heterogeneity of stroke into account, because of differences in the acute management, secondary prevention, and outcomes, according to the subtype and cause of stroke. In all types of stroke, early epileptic seizures, delirium, increased intracranial pressure, and non-specific complications are frequent. In ischaemic strokes, specific complications, such as malignant infarcts, spontaneous haemorrhagic transformation, early recurrence, and a new ischaemic event in another vascular territory, are frequent. In haemorrhagic strokes, the major complication is the subsequent increased volume of bleeding. There is strong evidence that stroke patients should be treated in dedicated stroke units; each time 24 patients are treated in a stroke unit, instead of a conventional ward, one death and one dependence are prevented. This effect does not depend on age, severity, and the stroke subtype. For this reason, stroke unit care is the cornerstone of the treatment of stroke, aiming at the detection and management of life-threatening emergencies, stabilization of most physiological parameters, and prevention of early complications. In ischaemic strokes, besides this general management, specific therapies include intravenous recombinant tissue plasminogen activator, given as soon as possible and before 4.5 hours, otherwise aspirin 300 mg, immediately or after 24 hours in case of thrombolysis, and, in a few patients, decompressive surgery. In intracerebral haemorrhages, blood pressure lowering and haemostatic therapy, when needed, are the two targets, but surgery does not seem effective to reduce death and disability.
20
Leys, Didier, Charlotte Cordonnier, and Valeria Caso. Stroke. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0067_update_001.
Повний текст джерелаАнотація:
Stroke is a major public health issue. Many are treatable in the acute stage, provided patients are admitted soon enough. The overall incidence of stroke in Western countries is approximately 2400 per year per million inhabitants, and 80% are due to cerebral ischaemia. The prevalence is approximately 12 000 per million inhabitants. Stroke is associated with increased long-term mortality, handicap, cognitive and behavioural impairments, recurrence, and an increased risk of other types of vascular events. It is of major interest to take the heterogeneity of stroke into account, because of differences in the acute management, secondary prevention, and outcomes, according to the subtype and cause of stroke. In all types of stroke, early epileptic seizures, delirium, increased intracranial pressure, and non-specific complications are frequent. In ischaemic strokes, specific complications, such as malignant infarcts, spontaneous haemorrhagic transformation, early recurrence, and a new ischaemic event in another vascular territory, are frequent. In haemorrhagic strokes, the major complication is the subsequent increased volume of bleeding. There is strong evidence that stroke patients should be treated in dedicated stroke units; each time 24 patients are treated in a stroke unit, instead of a conventional ward, one death and one dependence are prevented. This effect does not depend on age, severity, and the stroke subtype. For this reason, stroke unit care is the cornerstone of the treatment of stroke, aiming at the detection and management of life-threatening emergencies, stabilization of most physiological parameters, and prevention of early complications. In ischaemic strokes, besides this general management, specific therapies include intravenous recombinant tissue plasminogen activator, given as soon as possible and before 4.5 hours, otherwise aspirin 300 mg, immediately or after 24 hours in case of thrombolysis, and, in a few patients, decompressive surgery. In intracerebral haemorrhages, blood pressure lowering and haemostatic therapy, when needed, are the two targets, but surgery does not seem effective to reduce death and disability.
21
Leys, Didier, Charlotte Cordonnier, and Valeria Caso. Stroke. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0067_update_002.
Повний текст джерелаАнотація:
Stroke is a major public health issue. Many are treatable in the acute stage, provided patients are admitted soon enough. The overall incidence of stroke in Western countries is approximately 2400 per year per million inhabitants, and 80% are due to cerebral ischaemia. The prevalence is approximately 12 000 per million inhabitants. Stroke is associated with increased long-term mortality, handicap, cognitive and behavioural impairments, recurrence, and an increased risk of other types of vascular events. It is of major interest to take the heterogeneity of stroke into account, because of differences in the acute management, secondary prevention, and outcomes, according to the subtype and cause of stroke. In all types of stroke, early epileptic seizures, delirium, increased intracranial pressure, and non-specific complications are frequent. In ischaemic strokes, specific complications, such as malignant infarcts, spontaneous haemorrhagic transformation, early recurrence, and a new ischaemic event in another vascular territory, are frequent. In haemorrhagic strokes, the major complication is the subsequent increased volume of bleeding. There is strong evidence that stroke patients should be treated in dedicated stroke units; each time 24 patients are treated in a stroke unit, instead of a conventional ward, one death and one dependence are prevented. This effect does not depend on age, severity, and the stroke subtype. For this reason, stroke unit care is the cornerstone of the treatment of stroke, aiming at the detection and management of life-threatening emergencies, stabilization of most physiological parameters, and prevention of early complications. In ischaemic strokes, besides this general management, specific therapies include intravenous recombinant tissue plasminogen activator, given as soon as possible and before 4.5 hours, mechanical thrombectomy in case of proximal occlusion (middle cerebral artery, intracranial internal carotid artery, basilar artery), on top of thrombolysis in the absence of contraindication or alone otherwise, aspirin 300 mg, immediately or after 24 hours in case of thrombolysis, and, in a few patients, decompressive surgery. In intracerebral haemorrhages, blood pressure lowering and haemostatic therapy, when needed, are the two targets, while surgery does not seem effective to reduce death and disability.