Дисертації з теми "CoA ligases"
Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями
Ознайомтеся з топ-50 дисертацій для дослідження на тему "CoA ligases".
Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.
Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.
Переглядайте дисертації для різних дисциплін та оформлюйте правильно вашу бібліографію.
Lelievre, Chloé. "Formation de liaisons amides par réactions enzymatiques détournées ATP Regeneration System in Chemoenzymatic Amide Bond Formation with Thermophilic CoA Ligase." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASF026.
Повний текст джерелаThe amide function is widespread in nature and also in many synthetic products such as pharmaceuticals and polymers. Numerous approaches have been developed to provide reliable synthesis methods. The most common approach in conventional chemistry is the acylation of an amine by activated carboxylic acid. Activation requires the use of either coupling reagents resulting in low atom economy, or expensive catalysts sometimes used under drastic conditions. Biocatalytic approaches are therefore interesting alternatives for economic and environmental reasons. Different enzymes can be used such as hydrolases, nitrile hydratases and transglutaminases that activate the acid in acyl-enzyme form to promote the nucleophilic addition of the amine. In recent years, interest in ATP-dependent enzymes has increased.In this project, we focused on CoA ligases that catalyze the formation of activated acid as acyl-adenylate and then acyl-thioester. We have thus demonstrated that by diverting the reaction by scavenging activated intermediate with an amine, we obtain the amide. The use of thermophilic CoA ligases allows us to work at a high temperature and thus facilitate the uncatalyzed addition of the amine. This system therefore dispenses with the use of expensive HSCoA. For a better system, we have also successfully integrated an ATP regeneration system with a Polyphosphate Kinase 2 (Class III) and an inorganic pyrophosphatase. The efficiency of this cascade was illustrated by the lab-scale chemo-enzymatic synthesis of N-methylbutyrylamide in 77 % yield using low enzyme loading.Biodiversity exploration using a genomic approach based on sequence comparison allowed us to identify several thermophilic CoA ligases active towards ω-amino acid substrates. K6Q029 from Thermaerobacter subterraneus was further studied. In particular, this enzyme is active towards ω-amino acid substrates, functionalized or not, with more or less long carbon chains, as well as on various carboxylic acids such as aromatics.Thanks to the structural resolution of A4YDT1, a promiscuous CoA ligase from the literature, we have identified, in collaboration with a team of crystallographers from theUniversity of Groningen (Netherlands), the residues involved in its substrate specificity to modify them by a rational approach. Variants of this enzyme have thus allowed to obtain δ-valerolactam and Ɛ-caprolactam
Touré, Océane. "Approche biocatalytique pour la synthèse de lactames." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASF027.
Повний текст джерелаBiotechnology is now a well-established part of the chemical industry landscape. In the field of biocatalysis, there are numerous examples of the successful implementation of enzymatic steps in synthesis processes or the development of complete enzymatic pathways, particularly in the pharmaceutical industry.Lactams are compounds found in many natural and synthetic products, such as active pharmaceutical ingredients (APIs), and are precursors in polymer chemistry. To access lactams from simple omega-amino acid backbones, synthesis requires a two-step process: first, activation of the acid function, followed by intramolecular nucleophilic amine addition. For small lactams (5-7 members), intramolecular cyclization occurs spontaneously once the acid has been activated.As part of our work on enzymatic access routes to amides, we recently developed a synthesis involving activation by CoA ligases, in the absence of CoASH, and using only their ability to activate the acid by adenylation with ATP, introduced at only 5 mol% thanks to the implementation of a regeneration system.Until now, the type of lactams obtained by biocatalysis has been limited to bare, functionless rings. The aim of the project is to provide enzymes for the biocatalytic synthesis of 5- to 7-membered functionalized lactams. To achieve this, two approaches will be pursued:1) Exploration of biodiversity. A collection of CoA ligase enzymes, built up using a genomic approach based on sequence identity, is available in the laboratory. This collection, comprising around 250 enzymes, will be screened on lactam precursor substrates of interest. Adenylation enzymes other than CoA ligases have been identified and will also be tested.2) Rational design. In collaboration with the team of Prof. Dick Janssen and Dr. Andy-Mark Thunnissen (University of Groningen, Netherlands), structural data will be used to generate targeted libraries. Substrate docking experiments will be carried out to target mutations
Menzies, Sam. "Ubiquitin E3 ligase mediated regulation of HMG-CoA Reductase." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/273763.
Повний текст джерелаSouza, Clarice de Azevedo. "The Acyl-CoA ligase-like (ACLL) gene family in Arabidopsis and poplar." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/31283.
Повний текст джерелаScience, Faculty of
Botany, Department of
Graduate
Proctor, Lavinia M. "Pharmacological activity of C3a and C3a receptor ligands /." [St. Lucia, Qld.], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18423.pdf.
Повний текст джерелаRampersad, Marilyn Vena. "The development of N2S2 metal complexes as bidentate ligands for organometallic chemistry." Diss., Texas A&M University, 2005. http://hdl.handle.net/1969.1/4913.
Повний текст джерелаPrado, Rogilene Aparecida. "Clonagem gênica e caracterização de uma enzima tipoluciferase de coleópteros não bioluminescentes e sua relação com a origem da atividade luminescente." Universidade Federal de São Carlos, 2012. https://repositorio.ufscar.br/handle/ufscar/5399.
Повний текст джерелаUniversidade Federal de Minas Gerais
Bioluminescence in beetles is dependent on luciferase which evolved from AMP/CoA ligases. The cDNA of a luciferase-like enzime was cloned from the Malpighian tubules of Zophobas morio mealworm (Coleoptera: Tenebrionidae). The gene product of this cDNA displays weak luminescence and it is composed of 528 aminoacids residues with N-terminal and C-terminal sequences signal addressed to smooth endoplasmic reticulum membrane. Although having a low identity (26-32%) with beetle luciferases, this enzyme is a reasonable protoluciferase model to investigate the origin and evolution of beetle luciferases. The luciferin binding site is higly conserved among the beetle luciferases. However, in this protoluciferase of Z. morio, most of these residues of this motif are substituted by others. Using a site-directed mutagenesis survey some of aminoacids residues of this protoluciferase, which are located at correspondent luciferin binding site of luciferases, were replaced by the conserved residues of beetle luciferases. Most of the substitutions had negative effect on the luminescent activity, however, the substitution I327T, which is located in a β-hairpin motif close to the luciferin binding site, improved the luminescence activity. Such substitution indicates the importance of this motif for luciferase activity and indicates a possible route for the evolution of bioluminescence function of beetle luciferase. Since this enzyme is located in the Malpighian tubules, which are involved in excretion and metabolization of carboxylic substrates, this enzyme could be involved to excretion the some type of chemical compound. Regardless of the function the results show that the potential for bioluminescent activity is older and probably arose before the divergences of the Coleoptera bioluminescent families.
A bioluminescência em coleópteros é dependente das luciferases, enzimas que evoluíram das AMP-CoA ligases. O cDNA de uma enzima tipo-luciferase foi clonado dos túbulos de Malphighi de larvas de Zophobas morio (Coleoptera: Tenebrionidae). O produto gênico deste cDNA mostra naturalmente uma fraca luminescência na presença de MgATP e luciferina e possui 528 aminoácidos com sequências sinal na região N-terminal e C-terminal endereçadas a membrana do retículo endoplasmático liso. Apesar de ter uma baixa identidade (26-32%) com as luciferases de vaga-lumes, esta enzima é um modelo apropriado de protoluciferase para investigar a origem e evolução das luciferases de besouros. O sítio de ligação da luciferina é altamente conservado entre todas as luciferases de besouros; na protoluciferase de Z. morio porém, a maioria dos resíduos desta região é substituído por outros. Utilizando-se a técnica de mutagênese sitio-dirigida, alguns resíduos de aminoácidos desta protoluciferase, que são localizados na correspondente região do sítio ativo das luciferases, foram substituídos pelos resíduos conservados das luciferases. A maioria das substituições teve um efeito negativo sobre a atividade luminescente. Porém, a substituição I327T, cujo resíduo é localizado em um motivo grampo β, perto do sítio de ligação da luciferina, aumentou sua atividade luminescente. Tal substituição mostra a importância deste motivo para a atividade luciferásica e indica uma possível rota de evolução das luciferases de coleópteros. Uma vez que esta enzima foi extraída dos túbulos de Malpighi, é possível que esteja envolvida com a excreção de algum composto químico. Independente de sua função, os resultados do presente trabalho sugerem que o potencial para atividade bioluminescente é bem antigo nas ligases e provavelmente evoluíram antes da divergência das famílias de coleópteros bioluminescentes.
Wendt, Kerstin Sybille. "Zwei Untereinheiten aus Proteinkomplexen die Kristallstruktur der APC10-Untereinheit des humanen Anaphase-promoting-Complex und die Kristallstruktur der Carboxytransferase-Untereinheit der Glutaconyl-CoA-Decarboxylase aus Acidaminococcus fermentans /." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965479730.
Повний текст джерелаStudart-Guimarães, Claudia Rodriguez. "Functional analysis of the role of succinyl CoA ligase in the photosynthetic metabolism of tomato." [S.l.] : [s.n.], 2006. http://www.diss.fu-berlin.de/2006/409/index.html.
Повний текст джерелаTron, Cecile M. V. "Structural and functional studies of biotin protein ligase and its bacterial substrate acetyl-CoA carboxylase." Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/14582.
Повний текст джерелаLamm, Teresa Renée. "Redox modulation of acyl-CoA dehydrogenases (ACDs) and their ligands in several ACD-analog systems /." Diss., ON-CAMPUS Access For University of Minnesota, Twin Cities Click on "Connect to Digital Dissertations", 2001. http://www.lib.umn.edu/articles/proquest.phtml.
Повний текст джерелаMicheletto, Mariana Chaves. "Clorocatecol 1,2-dioxigenase e Proteína Ligante de Acil-CoA: caracterização estrutural e interações com ligantes." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/59/59135/tde-01122016-092008/.
Повний текст джерелаIn this study, we used a multi technique approach to understand the basic molecular interactions of two proteins that have quite different biological functions. The first, chlorocatechol 1,2- dioxygenase (Pp 1,2-CCD), has an environmental appeal due to it ability to catalyze the degradation of chlorocatechol, a common intermediate in the end of the decomposition of many polycyclic aromatic hydrocarbons. This characteristic of decontaminating polluted soils and waters suggest a great potential for applications in bioremediation mechanisms. Moreover, the presence of amphipathic molecules at the interface of the CCD monomers raised issues related to the ability of this enzyme family of binding to biological membranes. Such information broadens the knowledge of the basic mechanisms of enzyme action, increasing the possibility of interaction partners and may lead to other forms of control of the biological activity for use in biotechnological applications, such as biosensors development. The study of this enzyme is therefore, aimed at understanding their interactions with mimetic membrane and immobilization attempts of the protein in these structures. For this purpose, we make use of biophysical techniques such as circular dichroism, differential scanning calorimetry and optical spectroscopies and biomolecular techniques, such as development of primers, polymerase chain reaction and restriction analysis. The other aspect of this dissertation is focused on the study of acyl-CoA binding protein of Cryptococcus neoformans (CnACBP) cloned for first time in our laboratory. Homologues of ACBP were found in all organisms distributed in the four kingdoms of eukaryotes, with high sequence similarity (~ 48%). Its widespread presence and their involvement in several key metabolic pathways related to the acyl-CoA ester led to the conclusion that ACBP is a housekeeping protein and not a specific protein contained a specialized cell type. Here we present an initial characterization of CnACBP that seeks to relevant issues regarding the proteins function. Our goal was to increase the still vague knowledge on how electrical charges and the presence of the binding partner may influence the structure, stability and function through thermodynamic and spectroscopic techniques. This is an initial step toward the full understanding of the role of protein in the cell.
Allina, Sandra Mary. "Phenylpropanoid metabolism in poplar, characterization of the 4-coumarate:CoA ligase gene family and a putative hydroxycinnamoyl-CoA thioesterase." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ38847.pdf.
Повний текст джерелаHung, Laurence. "Etude d’un procédé d’extraction en milieu CO2 supercritique de l’uranium à partir de minerais." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM4310.
Повний текст джерелаThe research of clean and sustainable new processes to extract uranium from ores as an alternative to solvent extraction leads one to consider extraction processes using supercritical carbon dioxide. The aim of this work is to study the extraction feasibility of uranium ores by supercritical CO2, using suitable ligands. First, solubility measurements of selected ligands, trioctylamine and PC88A (2-ethylhexyl 2-ethylhexylphosphonic acid), and metal complexes formed between these ligands and molybdenum (uranium surrogate) or uranium, are performed in supercritical CO2. Supercritical CO2 extractions are then carried out on sulfuric aqueous solutions containing molybdenum and on molybdenum oxides powder. Solubilization of the extractant system (ligand/acid/oxidant) and solid leaching are the key steps which need to be controlled. Well-suited extractant system selection is therefore fundamental. The hypothetical mechanisms, describing supercritical carbon dioxide extraction, seem to be quite different from those usually observed in solvent extraction, especially in terms of selectivity and formed complex structure. Based on the results obtained with molybdenum, extraction trials on uranium ores were then conducted using PC88A in supercritical carbon dioxide with sulfuric acid and manganese oxide. More than 60% of uranium was recovered, which confirmed this new process feasibility. However, the influence of some operating parameters and the synthesis/selection of new suitable ligands remain to be further studied
Stromberger, Carmen [Verfasser]. "Screen for abnormal mitochondrial phenotypes in mouse embryonic stem cells identifies a model for succinyl-CoA ligase deficiency and mtDNA depletion / Carmen Stromberger." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2015. http://d-nb.info/1079840907/34.
Повний текст джерелаJin, Guanghua. "Coordination chemistry and catalysis at iron : from non-innocent ligands to CO2 transformation." Thesis, Toulouse 3, 2015. http://www.theses.fr/2015TOU30155/document.
Повний текст джерелаThere is an increasing interest in the use of iron in coordination chemistry and catalysis because it is an earth abundant metal which exhibits a low toxicity. The first chapter is a bibliographic study concerning two areas of applications for iron: the combination of iron with non-innocent ligands leading to highly active catalysts, and the use of iron complexes for CO2 transformations at the stoichiometric and catalytic levels. In chapter 2, the synthesis and characterization of iron complexes bearing a cooperative non-innocent ligand are presented. The highly reactive compound [Fe(N(TMS)2)2] has been chosen as a precursor for the study of the coordination of the bis(picolyl)phosphine ligand under mild conditions. As a result, a family of mono- and di-meric iron complexes has been isolated and the non-innocent behavior of the ligand has been observed. The combination of several techniques: X-ray diffraction, NMR (in solution and in the solid state), EPR, Mössbauer and infrared spectroscopy allows to clearly characterize both diamagnetic and paramagnetic complexes. Chapter 3 focuses on the transformation of CO2 catalyzed by an efficient iron-based system. In this system, iron hydride complexes [Fe(H)2(diphosphine)2] have been chosen to catalyze the reductive functionalization of CO2 through a one-pot two steps strategy under mild conditions. The first step concerns the iron-catalyzed reduction of CO2 by hydroboranes affording a bis(boryl)acetal compound. This intermediate is then used as a source of methylene in functionalization reactions, leading to a series of organic compounds containing not only C-N but also C-O, C-S, and C-C bonds in good yields
Ohleier, Alexia. "Nickel mediated negishi and oxidative couplings." Thesis, Toulouse 3, 2017. http://www.theses.fr/2017TOU30074/document.
Повний текст джерелаThe aim of this research project is to promote the formation of new C-C bonds and the production of valuable chemicals by using chelated nickel complexes. The first part of this thesis is dedicated to [nickel(bis-phosphine)] complexes employed as catalysts for Negishi cross coupling reactions. Designed Ni(0) precatalyst [(dcpp)Ni(n2-toluene)] (dcpp = 1,3-bis(dicyclohexylphosphino)propane) promotes efficiently the Negishi cross coupling between aryl chlorides and phenylzinc chloride derivatives at low catalyst loadings (down to 0.2 mol% - 1 mol%) under mild conditions (THF, 60°C). Mechanistic investigations relying on stoichiometric reactions and DFT calculations prove the involvement of Ni(0)/Ni(II) intermediates rather than Ni(I)/Ni(III) species during the catalysis. The second part of this work deals with the oxidative coupling between ethylene and CO2 at bis-phosphine and bis-NHC chelated nickel complexes for the production of value-added chemicals. The equilibrium between [(dcpp)Ni(C2H4)] and [(dcpp)nickelalactone] has been investigated by kinetic studies. The subsequent cleavage of [(dcpp) nickelalactone] by pinacolborane leads to its reductive functionalization into a propanol derivative. Preliminary mechanistic and catalytic investigations have been undertaken. Moreover, new methodologies are provided for the synthesis of the first [(bis-NHC)Ni(C2H4)] and [(bis-NHC)nickelalactone] complexes
Kreft, Gabriel Luiz. "Interação e clivagem de DNA por complexos de Co2+ com ligantes tripodais n-doadores." reponame:Repositório Institucional da UFSC, 2014. https://repositorio.ufsc.br/xmlui/handle/123456789/132964.
Повний текст джерелаMade available in DSpace on 2015-05-19T04:05:41Z (GMT). No. of bitstreams: 1 333308.pdf: 2483116 bytes, checksum: 9bc13a8ec635182c0a3f52919af77c62 (MD5) Previous issue date: 2014
Muitos estudos têm sido realizados com o ácido desoxirribonucleico interagindo com pequenas moléculas, entre estas os compostos de coordenação que podem atuar como miméticos de enzimas presentes nos organismos vivos. Com essa finalidade, foram avaliados a clivagem e a interação do DNA com uma série de cinco compostos de Co2+ com ligantes N-doadores tetradentados: Co(TPA)Cl]ClO4, [Co(6-MeTPA)Cl]ClO4, [Co(6-Me2TPA)Cl]ClO4, [Co(BPQA)Cl]ClO4, e [Co(BQPA)Cl]ClO4. O DNA plasmidial pBSK II foi utilizado como modelo na técnica de eletroforese em gel de agarose. Foram realizados ensaios variando a concentração dos complexos para avaliar o efeito na atividade de clivagem, ensaios de cinética para comparar atividade com outros complexos da literatura, ensaios com inibidores de espécies reativas de oxigênio e ensaios com atmosfera de argônio com o intuito de verificar se o mecanismo de clivagem é hidrolítico ou oxidativo, ensaio com o ligante de sulco menor: distamicina e o ligante de sulco maior: verde de metila com o proposito de verificar a dependência da ligação com os sulcos e ensaios na presença de perclorato de lítio para verificar o efeito das interações eletrostáticas. Os cinco complexos são ativos frente a clivagem do DNA plasmidial, em concentrações na ordem de micromolar. Os complexos devem atuar por um mecanismo hidrolítico e são muito sensíveis ao efeito da força iônica. Nos ensaios cinéticos foram obtidos valores de kcat entre 0,98 h-1 a 6,02h-1, para pH 7,0 e valores de kcat entre 1,99 h-1 e 16,8 h-1 para pH 9,0, correspondendo a valores que aumentam a velocidade de reação na ordem de 108 a 109 comparados à hidrólise não catalisada do DNA. Também foram realizados ensaios com eletroforese com gel de poliacrilamida de alta resolução, como modelo utilizado foi uma sequência de 49 nucleotídeos. Foi verificado que os compostos [Co(6-MeTPA)Cl] e [Co(BPQA)Cl] clivam o DNA em todos os nucleotídeos formando produtos com terminal 3´-PO32-, sem gerar produtos típicos de mecanismos oxidativos.
Abstract: Many studies have been conducted with the deoxyribonucleic acid interacting with small molecules, within them coordination compounds which may act as enzyme mimics in living organisms.For this purpose cleavage and interaction with DNA were evaluated for a series of five Co(II) compounds with tetradentate N-donor ligands: [Co(TPA)Cl]+, [Co(6-MeTPA)Cl]+, [Co(6-Me2TPA)Cl]+ [Co(BPQA)Cl]+ and [Co(BQPA)Cl]+. The plasmid DNA pBSK II was used as substrate in gel electrophoresis assays were performed varying the concentration of the complex, kinetic assays to assess DNA cleavage, trials with inhibitors of reactive oxygen species, trials with argon, assays with DNA groove binders and assays in the presence of lithium perchlorate to verify the effect of electrostatic interactions. The five complexes are active against the cleavage of plasmid DNA at concentrations on the order of micromolar.Complexes may act by a hydrolytic mechanism, are very sensitive to ionic strength effect. In kinetic experiments were obtained values of kcatbetween0,98 h-1to 6,02 h-1for pH 7.0 and values of kcat between 1,99 h-1to 16,8 h-1for pH9.0, corresponding to values that increase the reaction rate about108 to 109compared to spontaneous hydrolysis of DNA. Assays using high resolution polyacrylamide gel electrophoresis were made, the model used was a sequence of 49 nucleotides, it has been found that the compounds [Co (6-MeTPA) Cl] and [Co (BPQA) Cl] cleave DNA at all nucleotides forming products with 3'-PO32- termini without generating products of oxidative mechanism.
Petriccone, Massimo. "Dendrimères spécifiquement fonctionnalisés pour la catalyse en médias spéciaux." Electronic Thesis or Diss., Université de Toulouse (2023-....), 2024. http://www.theses.fr/2024TLSES048.
Повний текст джерелаThe presented research represents a comprehensive exploration of phosphorhydrazone (PPH) dendrimers, delving into their synthesis, functionalization, and catalytic applications, with a specific focus on para-substituted phenols for surface functionalization. The synthesis process entails a meticulous two-step reaction sequence, initiating from chlorinated phosphorus atoms in the core and progressing through substitution with 4-hydroxybenzaldehyde, ultimately culminating in dendrimer generation through condensation with MMHP(S)Cl2. To enable subsequent metal introduction were synthesized different phenolic derivates, alongside a model molecule designed to emulate iminophosphine reactivity while addressing phosphine oxidation concerns. The synthesis of bidentate phenols was described in detail, emphasizing the challenges faced and optimizations made, with a particular focus on the scalability of the procedures. The research also explores the modification of dendrimer surfaces to enhance solubility, with a specific emphasis on integrating perfluorinated ligands. Despite challenges in overall yield, alternative synthetic pathways were considered, resulting in the successful synthesis of phenols functionalized in the para position with alkylpolyfluorinated chains of varying lengths. Moving on to the characterization of PPH dendrimers, the study begins with the preparation of (1-methylhydrazineyl)phosphonothioic dichloride (MMHP(S)Cl2). Model molecules were synthesized to simulate PPH dendrimer surfaces, progressing to higher dendrimer generations. Distinctive features of PPH dendrimers, including their identification through 31P-NMR, were highlighted. A significant challenge in this phase involved ensuring the scalability of PPH dendrimer synthesis, which was successfully overcome. The research then shifts its focus to the precise functionalization of PPH dendrimers with previously synthesized phenolic substituents. The objective was to minimize di-symmetric substitution during the precise di-functionalization of the P(S)Cl2 function. Catalyst synthesis involved ligands with metal complexation for stability. Both precisely and stochastically substituted PPH dendrimers were successfully scaled up to the gram scale. In the final segment, the research delves into the catalytic activity of dendrimeric catalysts in various coupling reactions, both in organic and non-conventional solvents. Stille cross-coupling, Heck cross-coupling, and Suzuki coupling reactions were explored. The dendrimeric catalyst exhibited heightened activity in the Stille cross-coupling, showcasing a positive multivalence and generation dendritic effect. Despite insolubility in scCO2, the catalyst demonstrated activity for the Stille cross-coupling in heterogeneous conditions, emphasizing a positive generation dendritic effect. Additionally, the dendrimeric catalyst showed activity for the Heck cross-coupling in a biphasic fluorous/organic system. The study also addresses challenges associated with catalyst recovery in both organic and non-conventional solvents. Comparisons between precisely and stochastically difunctionalized dendrimers underscore positive multivalence and generation dendritic effects in specific reactions. Notably, higher activity of precisely substituted dendrimers from generation 1 to 3 compared to stochastically substituted homologues was demonstrated in the Stille cross-coupling. In summary, this research provides a thorough examination of dendrimer synthesis, functionalization, and catalytic applications, offering valuable insights and suggesting avenues for future refinement in sustainable catalytic processes
Billodeaux, Damon Ray. "Investigations on the use of main group metal complexes of salen ligands as catalysts for the copolymerization of CO2 and epoxides." Texas A&M University, 2005. http://hdl.handle.net/1969.1/2425.
Повний текст джерелаFogeron, Thibault. "Synthèse de complexes inspirés des formiate déshydrogénases à Mo/W : application à la catalyse moléculaire de la réduction du CO2." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS132.
Повний текст джерелаIn the context of global warming, the development of new sources of energy, clean and sustainable, is a key challenge of our society. The reduction of CO2 could allow the storage of renewable energies and offer an answer to the dramatic increase of CO2 in the atmosphere. Development of molecular catalysts offers the possibility of studying the structure-reactivity relationships. However, the library of existing homogeneous catalysts in the literature is quite limited. In order to find new potential catalysts, we decided to take inspiration from the active site of formate dehydrogenases (FDH). The synthesis of molecules mimicking this active site is an interesting challenge. In this thesis, we described the synthesis of two ligands inspired from the molybdopterin (chapter I). The synthesis of CoCp(dithiolène) complexes allows us to better characterize these ligands (chapter II). Moreover, the observation of the reactivity of these ligands allows us to understand their behaviour during electrocatalysis. The [MoO(dithiolene)2]2- complexes obtained from the bio-inspired ligands are,so far, the best mimics of the active site of FDH in the literature (chapter III). In this chapter, the generalization of synthetic procedure was also explored. Finally, [Ni(dithiolene)2]- synthesize from the bio-inspired ligands are the first dithiolene complexes able to reduce CO2 (chapter IV). They are among the few non-nobles metal complexes catalyzing the reduction of CO2 into formate
Cardoso, Amanda da Silva. "Estudo da corrosão de ligas Fe-Cr-Mo em água artificial de tanque de armazenamento de petróleo saturada com CO2." reponame:Repositório Institucional da UFC, 2012. http://www.repositorio.ufc.br/handle/riufc/9602.
Повний текст джерелаSubmitted by José Jairo Viana de Sousa (jairo@ufc.br) on 2014-10-15T19:28:50Z No. of bitstreams: 1 2012_dis_ascardoso.pdf: 1550155 bytes, checksum: 52c246f369a8b1fdd15b0b9052264efa (MD5)
Approved for entry into archive by José Jairo Viana de Sousa(jairo@ufc.br) on 2014-10-30T19:08:30Z (GMT) No. of bitstreams: 1 2012_dis_ascardoso.pdf: 1550155 bytes, checksum: 52c246f369a8b1fdd15b0b9052264efa (MD5)
Made available in DSpace on 2014-10-30T19:08:30Z (GMT). No. of bitstreams: 1 2012_dis_ascardoso.pdf: 1550155 bytes, checksum: 52c246f369a8b1fdd15b0b9052264efa (MD5) Previous issue date: 2012
The objective of this work was to evaluate the influence of the percentage in mass of Mo in Fe-Cr-Mo alloys against CO2 corrosion in artificial water of oil storage tank and to propose an experimental alloy to be used in susceptible to this kind of corrosion pipes. They had been studied the 1020 carbon steel, for comparison, and two types of Fe-Cr-Mo alloys, one advertising, called P9 (Fe-9Cr-1Mo); and one experimental alloy, E (Fe-9Cr-5Mo). They had been made measurements of LSP with time of Eoc of 1 h. The curves had shown that, in 1020 steel, the dissolution of Fe occurs only, whereas, with the increase of the percentage of Mo, occurs passivation. Monitoring of the corrosion was made by electrochemical impedance spectroscopy, throughout 168 h of immersion. Nyquist diagrams had shown that the increase of Mo content increased the impedance of the studied alloys. Although, the Bode representations showed that there is only one process in the corrosion of 1020 steel, while there are two ones for P9 and E alloys. The characterization of the surface was made by SEM. The distribution of the corrosion products was homogeneous in the 1020 steel and heterogeneous one in the other alloys. The identification of the corrosion products was made by RAMAN spectroscopy, showing that there was protective corrosion products formation only to Fe-Cr-Mo alloys and that only the E alloy presented Mo-containing products. This is in agreement with the results obtained in polarization curves and in impedance diagrams, once Mo can stabilizes passivation films. So, experimental E alloy can be used in substitution of P9 alloy in oil exploration plants susceptible to CO2 corrosion.
O objetivo deste trabalho foi avaliar a influência da porcentagem em massa de Mo em ligas Fe-Cr-Mo frente à corrosão por CO2 em água artificial de tanque de armazenamento de petróleo e propor uma liga experimental para ser usada em dutos suscetíveis a esse tipo de corrosão. Foram estudados o aço carbono 1020, para comparação, e dois tipos de ligas Fe-Cr-Mo, uma comercial, denominada P9 (Fe-9Cr-1Mo); e uma liga experimental, E (Fe-9Cr-5Mo). Foram feitas medidas de PLP com tempo de Eca de 1 h. As curvas mostraram que, no aço 1020, ocorre apenas a dissolução do Fe, enquanto que, com o aumento da porcentagem de Mo, ocorre passivação. O monitoramento da corrosão foi feito por espectroscopia de impedância eletroquímica, ao longo de 168 h de imersão. Os diagramas de Nyquist mostraram que o aumento na quantidade de Mo aumenta a impedância das ligas estudadas. Já as representações de Bode mostraram que há apenas um processo na corrosão no aço 1020, enquanto que há dois para as ligas P9 e E. A caracterização da superfície foi feita por MEV. A distribuição dos produtos de corrosão foi homogênea no aço 1020 e heterogênea nas demais ligas. A identificação dos produtos de corrosão foi feita por espectroscopia RAMAN, mostrando que houve a formação de produtos de corrosão protetores apenas para as ligas Fe-Cr-Mo e que apenas a liga E apresentou produtos contendo Mo. Isso está em acordo com os resultados obtidos nas curvas de polarização e nos diagramas de impedância, uma vez que o Mo pode estabilizar filmes de passivação. Assim, a liga experimental E pode ser usada em substituição à liga comercial P9 em plantas de exploração de petróleo suscetíveis a corrosão por CO2.
Nambukara, Wellala Nadeesha P. "Synthesis and Catalytic Activities of Nickel Complexes Bearing Flexible Tridentate Ligands." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1491561548324255.
Повний текст джерелаChristophe, Thierry. "Etude de la régulation du récepteur de l'anaphylatoxine C5a : identification de ligands des récepteurs de la famille FPR." Université Joseph Fourier (Grenoble), 2000. http://www.theses.fr/2000GRE10229.
Повний текст джерелаBaffert, Mathieu. "Synthesis of ruthenium complexes having one or more N-heterocyclic carbene ligands supported on hybrid mesostructured silicas and their use in the hydrogenation of carbon dioxide." Phd thesis, Université Claude Bernard - Lyon I, 2011. http://tel.archives-ouvertes.fr/tel-00838661.
Повний текст джерелаDamineli, Bruno Luís. "Conceitos para formulação de concretos com baixo consumo de ligantes: controle reológico, empacotamento e dispersão de partículas." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/3/3146/tde-19092014-103459/.
Повний текст джерелаDue to the increasing demand of developing countries, cement production and related CO2 emissions increases steadily, putting industry under pressure due to global warming constraints. As decreasing production is not a sustainable option from social point of view, environmental loads need to be decreased even maintaining the increase of production. However, current strategies for reducing emissions clinker replacement by mineral additions, increase of kiln efficiency and the use of alternative fuels are not capable of a reduction which could compensate the increasing in production, even with the dissemination of highest industrial efforts due to technological and materials availability limits. Carbon capture and storage, by the time, could increase significantly cement cost, which could harm exactly the neediest countries. New alternatives are needed. One of them, few developed yet, is increasing the efficiency of binder use on cementitious materials, such as concretes. This thesis has the aim of exploring the potential of this strategy for contributing to the mitigation of CO2 emissions of concrete/cement chain. The success in this task is directly related to the use of tools of packing and dispersion of particles for allowing an adequate rheological behavior for the application but with a lower water content in the mixture. The thesis was divided in three main steps: 1) literature research for creating a benchmark of current concrete technology in terms of binder efficiency by two efficiency indexes Binder Intensity (BI) and CO2 Intensity (CI); 2) research of particles packing and dispersion theory; and 3) experimental planning for demonstrating how the binder use efficiency can be significantly increased by the use of concepts from step 2, a more precise rheological behavior control and the use of inert fillers for replacing clinker to obtain rheological parameters. It could be concluded that the potential of efficiency increase is higher than 50%. However, the implantation in commercial scale would depend on the increase of technological control in concrete designs, and also on deep changes in the productive chain and in the definitions of aggregates, fillers, cement and binders.
Gautier, Quentin, and Quentin Gautier. "Cinétiques de précipitation de minéraux carbonatés magnésiens, influence de ligands organiques et conséquences pour la séquestration minérale du CO2." Phd thesis, Université Paris-Est, 2012. http://pastel.archives-ouvertes.fr/pastel-00806512.
Повний текст джерелаGautier, Quentin. "Cinétiques de précipitation de minéraux carbonatés magnésiens, influence de ligands organiques et conséquences pour la séquestration minérale du CO2." Thesis, Paris Est, 2012. http://www.theses.fr/2012PEST1128/document.
Повний текст джерелаForming magnesium carbonate minerals through carbonation of magnesium silicates has been proposed as a safe and durable way to store carbon dioxide, with a possibly high potential to offset anthropogenic CO2 emissions. To date however, chemical reactions involved in this process are facing strong kinetic limitations, which originate in the low reactivity of both Mg-silicates and Mg-carbonates. Numerous studies have focused on the dissolution of Mg-silicates, under the questionable hypothesis that this step limits the whole process. This thesis work focuses instead on the mechanisms and rates of formation of magnesium carbonates, which are the final products of carbonation reactions. The first part of the work is dedicated to studying the influence on magnesite precipitation kinetics of three organic ligands known to accelerate Mg-silicates dissolution rates : oxalate, citrate and EDTA. With help of mixed-flow reactor experiments performed between 100 and 150°C, we show that these ligands significantly reduce magnesite growth rates, through two combined mechanisms: (1) complexation of Mg2+ cations in aqueous solution, which was rigorously estimated from a thermodynamic database established through a critical review of the literature, and (2) adsorption of ligands to a limited number of surface sites, leading to a decrease of the precipitation rate constant. The observed growth inhibition is maximal with citrate. We then used hydrothermal atomic force microscopy to probe the origin of the documented growth inhibition. Our observations show that citrate and oxalate interact with the crystal growth process on magnesite surface, modifying the shape of growth hillocks as well as the step generation frequency through spiral growth. We also show that the ligands adsorb preferentially on different kink-sites, which is probably related to their different structures and chemical properties. We propose that the stronger magnesite growth inhibition caused by citrate is related to a preferential interaction of the ligand with acute steps on the magnesite surface, which limit the spiral growth process through their low advancement rate. The description of these processes with an empirical rate law allows performing simple numerical simulations of forsterite carbonatation at 120°C in the presence of the ligands. We thus demonstrate that the use of the investigated ligands would clearly be detrimental to the carbonation of forsterite. The third and last part of this work deals with hydromagnesite solubility and growth kinetics between 25 and 75°C. The obtained results show that hydromagnesite growth rates largely exceed magnesite rates at comparable chemical affinity, while the activation energy of the process is much smaller than for magnesite. This original kinetic dataset thus confirms the long-standing hypothesis that Mg2+ dehydration is the rate-limiting step for Mg-carbonate precipitation from aqueous solution. However, due to its higher solubility, hydromagnesite may grow more quickly than magnesite only at low temperature and alkaline pH. Thus, it may not provide a solution to the sluggish precipitation kinetics of magnesite during Mg-silicates carbonation
Cardoso, Amanda da Silva. "Estudo da corrosÃo de ligas Fe-Cr-Mo em Ãgua artificial de tanque de armazenamento de petrÃleo saturada com CO2." Universidade Federal do CearÃ, 2012. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=8477.
Повний текст джерелаConselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico
O objetivo deste trabalho foi avaliar a influÃncia da porcentagem em massa de Mo em ligas Fe-Cr-Mo frente à corrosÃo por CO2 em Ãgua artificial de tanque de armazenamento de petrÃleo e propor uma liga experimental para ser usada em dutos suscetÃveis a esse tipo de corrosÃo. Foram estudados o aÃo carbono 1020, para comparaÃÃo, e dois tipos de ligas Fe-Cr-Mo, uma comercial, denominada P9 (Fe-9Cr-1Mo); e uma liga experimental, E (Fe-9Cr-5Mo). Foram feitas medidas de PLP com tempo de Eca de 1 h. As curvas mostraram que, no aÃo 1020, ocorre apenas a dissoluÃÃo do Fe, enquanto que, com o aumento da porcentagem de Mo, ocorre passivaÃÃo. O monitoramento da corrosÃo foi feito por espectroscopia de impedÃncia eletroquÃmica, ao longo de 168 h de imersÃo. Os diagramas de Nyquist mostraram que o aumento na quantidade de Mo aumenta a impedÃncia das ligas estudadas. Jà as representaÃÃes de Bode mostraram que hà apenas um processo na corrosÃo no aÃo 1020, enquanto que hà dois para as ligas P9 e E. A caracterizaÃÃo da superfÃcie foi feita por MEV. A distribuiÃÃo dos produtos de corrosÃo foi homogÃnea no aÃo 1020 e heterogÃnea nas demais ligas. A identificaÃÃo dos produtos de corrosÃo foi feita por espectroscopia RAMAN, mostrando que houve a formaÃÃo de produtos de corrosÃo protetores apenas para as ligas Fe-Cr-Mo e que apenas a liga E apresentou produtos contendo Mo. Isso està em acordo com os resultados obtidos nas curvas de polarizaÃÃo e nos diagramas de impedÃncia, uma vez que o Mo pode estabilizar filmes de passivaÃÃo. Assim, a liga experimental E pode ser usada em substituiÃÃo à liga comercial P9 em plantas de exploraÃÃo de petrÃleo suscetÃveis a corrosÃo por CO2.
The objective of this work was to evaluate the influence of the percentage in mass of Mo in Fe-Cr-Mo alloys against CO2 corrosion in artificial water of oil storage tank and to propose an experimental alloy to be used in susceptible to this kind of corrosion pipes. They had been studied the 1020 carbon steel, for comparison, and two types of Fe-Cr-Mo alloys, one advertising, called P9 (Fe-9Cr-1Mo); and one experimental alloy, E (Fe-9Cr-5Mo). They had been made measurements of LSP with time of Eoc of 1 h. The curves had shown that, in 1020 steel, the dissolution of Fe occurs only, whereas, with the increase of the percentage of Mo, occurs passivation. Monitoring of the corrosion was made by electrochemical impedance spectroscopy, throughout 168 h of immersion. Nyquist diagrams had shown that the increase of Mo content increased the impedance of the studied alloys. Although, the Bode representations showed that there is only one process in the corrosion of 1020 steel, while there are two ones for P9 and E alloys. The characterization of the surface was made by SEM. The distribution of the corrosion products was homogeneous in the 1020 steel and heterogeneous one in the other alloys. The identification of the corrosion products was made by RAMAN spectroscopy, showing that there was protective corrosion products formation only to Fe-Cr-Mo alloys and that only the E alloy presented Mo-containing products. This is in agreement with the results obtained in polarization curves and in impedance diagrams, once Mo can stabilizes passivation films. So, experimental E alloy can be used in substitution of P9 alloy in oil exploration plants susceptible to CO2 corrosion.
Juvenal, Frank. "Polymères de coordination luminescents 1D et 2D avec des ligands rigides contenant du Pt(II) montrants des propriétés d’adsorption du CO2." Mémoire, Université de Sherbrooke, 2017. http://hdl.handle.net/11143/10578.
Повний текст джерелаAbstract: The design of new functional materials has a long history. For the past two decades, the field of organic and inorganic polymers has attracted attention of researchers. More importantly, porous materials such as Metal Organic Frameworks (MOFs), Covalent Organic Frameworks (COFs) as well as porous coordination polymers are now being intensively studied due to their potential applications including gas storage, gas separations, catalyst and sensing. On another hand, Pt-containing polymers have shown potential applications in solar cells and light emitting diodes. The masters’ thesis is mainly divided into three main sections presenting new results. In the first section; Chapter 2 mainly discusses the formation of coordination polymers with CuX salts (X= Cl, Br, I) and trans-[p-MeSC6H4C≡C-Pt(PMe3)2-C≡CC6H4SMe] (L1), in either PrCN or PhCN. The resulting polymers obtained were 2D (bidimensional) CPs or 1D (unidimensional) CPs in all cases. However, 2D CPs obtained when CuBr salt is used by either using PrCN or PhCN did not incorporate the solvents in their cavities. On the other hand, the 2D CP and the rest of 1D CPs obtained had either the crystallization molecules in the cavities or coordinated to the copper cluster. The copper-halide clusters were either the rhomboids Cu2X2 fragments or the step cubane Cu4I4. The photophysical measurements in the presence and absence of solvent crystallization molecules were performed. In addition, the porosity of the CPs was evaluated by adsorption isotherms. The vapochromism of the solvent-free 2D and 1D CPs were investigated as well as CO2 sorption measurements were perfomed. Furthermore, we then attempted to use CuCN and L1 in MeCN which is reported in the second section as Chapter 3. The obtained CP was unexpected as L1 broke and a cyanide (CN‾) ion coordinated to the Pt atom leading to the formation of zigzag 1D CP. The coordination bonds Cu-S or/and Cu([eta]2-C≡C) were generally observed with L1, but not in the CuCN case. Instead a 1D chain of (CuCN)n was made and the broken L1 now binds the chain via a Cu-N bond. The photophysical and thermal stability properties were studied. Lastly, the third section, Chapter 4 deals with a potential predictability of CP formation by using CuX salts (X= Cl, Br, I) and either trans-[p-MeSC6H4C≡C-Pt(PMe3)2-C≡CC6H4SMe] (L1) or trans-[p-MeSC6H4C≡C-Pt(PEt3)2-C≡CC6H4SMe] (L2) in MeCN as the solvent. The use of L1 resulted in either 2D or 1D CPs with the MeCN trapped inside of the cavities while L2 resulted in 1D CPs without MeCN being present in their cavities. The thermogravimetric, photophysical as well as gas sorption measurements (only for those with crystalisation molecules) were perfomed.
Eckstein, Ilton Isandro. "Tipificação dos fatores ligados ao manejo de ordenha e avaliação do seu impacto sobre a qualidade sanitária do leite." Universidade Estadual do Oeste do Paraná, 2012. http://tede.unioeste.br:8080/tede/handle/tede/1645.
Повний текст джерелаCoordenação de Aperfeiçoamento de Pessoal de Nível Superior
Knowing the factors that affect the composition and quality of milk in Dairy Production Systems (SPL) is of utmost importance to the producer. The objective was to evaluate the characteristics of 32 SPL in the city of Toledo, together in partnership with a dairy. We performed the data collection of properties, with the aid of a semi-structured questionnaire, which collected information on the production traits, milk composition and quality, besides the technical and management practices carried out, mainly related to hygiene and management health of milking. Milk samples were analyzed for their composition (fat, protein, lactose and total solids), Somatic Cell Count (SCC), Total Bacterial Count (TBC), and also to the presence of total coliforms and fecal coliforms. Subsequently, data collection, the variables were selected and analyzed using multivariate techniques, using the principal component analysis (PCA) and analysis of Ascendant Hierarchical Classification (AHC). We analyzed variables related to production and milk quality, techniques and practices used at the time of milking, feeding management, milking system and socio-cultural variables related to the producer. The variables that best explained the differences in the PCA were related to the hygienic and sanitary practices (pre and post-dipping, use of detergents in alkaline and acid cleaning, testing for mastitis) held for milking, with the composition of milk and linked to the producer (age, education, length of service). It was found that the use of these practices can help to improve production and milk quality, ensuring a raw material with high commercial value. The grouping of production systems has shown that there is great diversity among the forms of production, allowing identifying the factors that can influence it, in order to form strategies that may result from gains in production and milk quality
Conhecer os fatores que afetam a composição e qualidade do leite em Sistemas de Produção Leiteiros (SPL) é de extrema importância ao produtor. Objetivou-se avaliar as características de 32 SPL, na cidade de Toledo, juntamente em parceria com um laticínio. Foi realizada a coleta de dados das propriedades, com o auxílio de um questionário semi-estruturado, onde se colheu informações acerca das características de produção, composição e qualidade do leite, além das técnicas e práticas de manejo realizadas, principalmente relacionadas ao manejo higiênico-sanitário de ordenha. As amostras de leite foram analisadas em relação a sua composição (gordura, proteína, lactose e sólidos totais), Contagem de Células Somáticas (CCS), Contagem Bacteriana Total (CBT), e também para presença de coliformes totais e coliformes termotolerantes. Posteriormente, a coleta de dados, as variáveis foram selecionadas e analisadas por meio de técnicas multivariadas, sendo utilizada a análise de Componentes Principais (ACP) e a análise de Classificação Hierárquica Ascendente (CHA). Foram analisadas variáveis relacionadas à produção e qualidade do leite, técnicas e práticas utilizadas no momento da ordenha, manejo alimentar, sistema de ordenha e variáveis sócio-culturais relacionadas ao produtor. As variáveis que melhor explicaram as diversidades das ACP foram as relacionadas com as práticas higiênico-sanitária (pré e pós-dipping, utilização dos detergentes alcalino e ácido na higienização, testes para detecção de mastite) realizadas na ordenha, com a composição de leite e vinculadas ao produtor (idade, escolaridade, tempo na atividade). Foi verificado que o uso destas práticas podem auxiliar para melhorar a produção e qualidade do leite, assegurando uma matéria-prima com maior valor comercial. O agrupamento dos sistemas de produção permitiu verificar a existência de grande diversidade entre as formas de produção, possibilitando identificar os fatores que podem influenciá-lo, a fim de formar estratégias que possam resultar ganhos em produção e qualidade do leite
Cheng, Chin-Min. "Leaching of coal combustion products field and laboratory studies /." Columbus, Ohio : Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1133195856.
Повний текст джерелаYu, Deyue. "Identification, caractérisation, et expression de nouveaux gènes chez Arabidopsis thaliana." Université Joseph Fourier (Grenoble), 1994. http://www.theses.fr/1994GRE10102.
Повний текст джерелаDias, Rogério de Matos. "Um modelo informacional para gestão de operações: o caso da Cia. Vale do Rio Doce - Depto. de Manganês e Ferro-Ligas." reponame:Repositório Institucional do FGV, 2003. http://hdl.handle.net/10438/3880.
Повний текст джерелаThis research aims to theoretically develop an informationaI modeI able to provide a fully integrated supply chain management for multiplant manufacturing companies, as well as to prove its feasibility in the field, using a combined action-research and case study investigation methodology for a representative mining&metals company - Cia. Vale do Rio Doce, Manganese and Ferroalloys Departament. The study also intends to describe how the proposed model can provide planning and control capabilities for the operational, tactical and strategic decision making leveIs, as result of the transational and managerial processes automatization, data analysis agility and increasing in the quality decision making processes. Moreover, the study also intends to describe the contributions of that informationaI model for the supply chain management in similar companies as well as to generalize the model's application for similar multiplant manufacturing companies.
Esta pesqUisa objetiva desenvolver, testar e demonstrar a aplicabilidade de um modelo infonnacional que possibilite a gestão integrada das operações da cadeia de suprimentos para indústrias geograficamente dispersas, também denominadas indústrias multi planta. Para tanto, serão aplicadas metodologias de estudo de caso e pesquisa-ação, em uma empresa representativa dos setores mineral e metalúrgico, o Departamento de Manganês e Ferro-Ligas da CVRD - Cia. Vale do Rio Doce. A pesquisa pretende demonstrar que o modelo de sistema infonnacional proposto, por meio da automatização dos processos transacionais e gerenciais, é capaz de prover recursos de planejamento e controle nos níveis operacional, tático e estratégico, devido a sua capacidade de incrementar a velocidade e a qualidade dos processos de análise e decisão. A pesquisa pretende conduzir, após análise dos resultados e avaliação das contribuições à empresa estudada, a um modelo informacional adequado para gerir as operações de outras empresas de mineração e metalurgia com características semelhantes.
Abrão, Pedro Cesar Rodrigues Alves. "O uso de pozolanas como materiais cimentícios suplementares: disponibilidade, reatividade, demanda de água e indicadores ambientais." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/3/3146/tde-26032019-084557/.
Повний текст джерелаThe cement is one of the most used materials in the modern world and its production should grow in the next 40 years. This growing production will be responsible for issuing a large volume of CO2 on the atmosphere, nowadays the cement industry is responsible worldwide for 10% of the total emissions of CO2 and it can reach 30% in 2050. Therefore, academia and industry are developing strategies to reduce this environmental impact, one of these strategies is the substitution of clinker by supplementary cementitious materials (SCMs). For this strategy to be effective it is necessary that these materials possess: (i) economic viability; (ii) availability and; (iii) technical feasibility. Today the most used supplementary materials are the blast furnace slag and fly ash, but the increase in the production of cement was not accompanied by the supply of these materials. Therefore, other supplementary materials are being used by the industry, as is the case of natural and artificial pozzolans. So, the aim of this work is to estimate the availability and geographic distribution of some supplementary cementitious materials in Brazil and evaluate the efficiency of six Portland pozzolan blended cements and compare them with a cement with high clinker content as to reactivity, water demand and environmental indicators. All materials were physically and chemically characterized; pastes and mortars were analyzed in terms of reactivity, water demand and mechanical strength; finally, environmental and efficiency indicators were estimated. For pastes and mortars without dispersant the cement with high content of clinker and those with the addition of diatomaceous earth ordered more water than the others to achieve the same spread, already with the addition of superplasticizer the cement REF was the one that ordered more water than the others. The cement with high clinker content was the most reactive in all ages and presented the best results of the binder efficiency indicator and binder intensity indicator. For the carbon intensity indicator, the best results were obtained for cements with high replacement content. However, the study shows that the reduction of the clinker content is not directly related to the reduction of the environmental impact of the cement in its use, this reduction is also associated with the binder efficiency in means of reactivity and water demand.
Galand, Nicolas. "Extraction liquide-liquide de cations par des molécules complexantes : Simulations des ligands et des complexes à l'interface entre l'eau et une phase organique ou le CO2 supercritique." Université Louis Pasteur (Strasbourg) (1971-2008), 2007. http://www.theses.fr/2007STR13191.
Повний текст джерелаBehm, Mariana Boneberger. "Síntese e avaliação de arranjos supramoleculares de triazenos monocatenados e complexos com os cátions Co3+, Cu2+, Ag+ e Au+." Universidade Federal de Santa Maria, 2010. http://repositorio.ufsm.br/handle/1/4196.
Повний текст джерелаTriazenes ligands substituted by terminal aryl groups in the diazoamine chain [ N=N N(H) ] containing NO2 group substituted in different position and ortho C(O)NH2 on aryl ring was evaluated on the occurrence of intermolecular interactions through hydrogen links. The research was based primarily on X-ray diffraction in single crystal to analyze structurally the occurrence of self-assembles supramolecular architectures on solid state. This work presents the synthesis and investigation of molecular and crystal structure of eleven new compounds. The pre-ligands 1-(2-amidofenil)-3-(2-nitrofenil)triazeno (I), 1-(2-amidofenil)-3-(4-nitrofenil)triazeno (II) e 1-(2-amidofenil)-3-(3-nitrofenil)triazeno (III), the cobalt(III) complexes: {Co[C(O)NHC6H4NNNC6H4NO2](C2H8N2)2}{Cl}.CH3OH (1), {Co[C(O)NHC6H4NNNC6H4NO2](C2H8N2)2}{Cl}.H2O (2) and {Co[C(O)NHC6H4NNNC6H4NO2](NH3)4}{NO3}.H2O (3), and silver(I) complexes: {Ag[C(O)NH2C6H4NNNC6H4NO2](C2H8N2)}{[C(O)NH2C6H4NNN(H)C6H4NO2]} (4) and {Ag[C(O)NH2C6H4NNNC6H4NO2](C2H8N2)]} (5), and cupper(II) complexes: {Cu4[C(O)NHC6H4NNNC6H4NO2]2[(OCH3)4]} (6) and gold(I) complexes: {Au[C(O)NH2C6H4NNNC6H4NO2](PC18H15)}{C5H5N} (7) e Au[C(O)NH2C6H4NNNC6H4NO2](PC18H15)] (8). Other complementary techniques were used to characterize the compounds, such as: infrared spectroscopy, 1H nuclear magnetic resonance spectroscopy, ultraviolet-visible spectroscopy, mass spectrometry, Raman spectroscopy and thermogravimetric analysis.
Ligantes triazenos substituídos nos grupos arilas terminais na cadeia diazoamínica [ N=N N(H) ] contendo os substituintes NO2 em diferentes posições e o grupo C(O)NH2 orto substituído ao anel foram avaliados quanto à ocorrência de interações intermoleculares através de ligações de hidrogênio. A investigação baseou-se principalmente na difração de raios-X em monocristal para analisar estruturalmente a formação de arranjos supramoleculares no estado sólido. Este trabalho apresenta a síntese e a investigação da estrutura cristalina e molecular de onze compostos inéditos: os pré-ligantes 1-(2-amidofenil)-3-(2-nitrofenil)triazeno (I), 1-(2-amidofenil)-3-(4-nitrofenil)triazeno (II) e 1-(2-amidofenil)-3-(3-nitrofenil)triazeno (III), os complexos de cobalto (III): {Co[C(O)NHC6H4NNNC6H4NO2](C2H8N2)2}{Cl}.CH3OH (1), {Co[C(O)NHC6H4NNNC6H4NO2](C2H8N2)2}{Cl}.H2O (2) e {Co[C(O)NHC6H4NNNC6H4NO2](NH3)4}{NO3}.H2O (3), os de prata (I): {Ag[C(O)NH2C6H4NNNC6H4NO2](C2H8N2)}{[C(O)NH2C6H4NNN(H)C6H4NO2]} (4) e {Ag[C(O) NH2C6H4NNNC6H4NO2](C2H8N2)]} (5), o de cobre (II): {Cu4[C(O)NHC6H4NNNC6H4NO2]2[(OCH3)4]} (6) e os de ouro (I): {Au[C(O)NH2C6H4NNNC6H4NO2](PC18H15)}{C5H5N} (7) e Au[C(O)NH2C6H4NNNC6H4NO2](PC18H15)] (8). Outras técnicas complementares foram utilizadas para caracterizar os compostos, como: espectroscopia de infravermelho, ressonância magnética nuclear 1H, espectroscopia do ultravioleta visível, espectrometria de massa, espectroscopia Raman e análise termogravimétrica.
Timmers, Luís Fernando Saraiva Macedo. "Estudos cristalográficos e aplicação da técnica de triagem virtual de ligantes para a busca de novos inibidores contra a enzima Citidina Deaminase (CDA; EC 3.5.4.5) de Mycobacterium tuberculosis H37Rv." Pontifícia Universidade Católica do Rio Grande do Sul, 2011. http://hdl.handle.net/10923/1295.
Повний текст джерелаThe consumption has been a scourge of mankind since ancient times. This illness have been charged a high price in human lives, so many efforts have been made in order to defeat the Mycobacterium tuberculosis. The complete genomics sequence of Mycobacterium tuberculosis opened a new era and had a major impact in our understanding of this pathogen and also in research for microbial drugs. The researches could identify genes and later validate the metabolic pathways. The better understanding of metabolic pathways present in Mycobacterium tuberculosis corresponds to a first step and configures a possibility of identification of new molecular targets that could be derail the bacilli. However, there is much more to do, since of the discovery of rifampicin, a first-line drug used effectively against TB, none new chemotherapy has been released. TB is nowadays responsible for two million of deaths/year and is a global emergency which needs to be urgently repressed. The present work aim to realize structural analysis of the enzyme Cytidine Deaminase (CDA; EC 3. 5. 4. 5) from Mycobacterium tuberculosis associated with substrates and products, allying techniques such as molecular docking and dynamics simulations.
A tuberculose tem sido um flagelo da humanidade desde os tempos antigos. Esta doença tem cobrado um preço alto em vidas humanas, por esta razão muitos esforços tem sido feitos com o intuito de derrotar o Mycobacterium tuberculosis. A sequência genômica do Mycobacterium tuberculosis deu início a uma nova era e foi de grande impacto para o presente conhecimento deste patógeno como também na pesquisa de drogas anti-microbiais. Com estes avanços foi possível identificar genes e mais tarde validar vias metabólicas. O melhor entendimento das vias metabólicas presentes no Mycobacterium tuberculosis corresponde ao primeiro passo e configura uma possibilidade de identificação de novos alvos moleculares que possam erradicar o bacilo. Entretanto, ainda há muito a fazer, desde a descoberta da Rifampicina, a droga de primeira linha efetivamente utilizada contra TB, nenhuma nova droga quimioterápica foi identificada. Nos dias de hoje, a TB é responsável pela morte de dois milhões de pessoas por ano, sendo considerada uma emergência global, a qual precisa ser urgentemente erradicada. O presente projeto tem o objetivo de realizar a análise estrutural da enzima Citidina Deaminase (CDA; EC 3. 5. 4. 5) de Mycobacterium tuberculosis associada com seus substratos e produtos, aliando técnicas de Dinâmica e Docagem molecular.
Timmers, Lu?s Fernando Saraiva Macedo. "Estudos cristalogr?ficos e aplica??o da t?cnica de triagem virtual de ligantes para a busca de novos inibidores contra a enzima Citidina Deaminase (CDA; EC 3.5.4.5) de Mycobacterium tuberculosis H37Rv." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2011. http://tede2.pucrs.br/tede2/handle/tede/5413.
Повний текст джерелаA tuberculose tem sido um flagelo da humanidade desde os tempos antigos. Esta doen?a tem cobrado um pre?o alto em vidas humanas, por esta raz?o muitos esfor?os tem sido feitos com o intuito de derrotar o Mycobacterium tuberculosis. A sequ?ncia gen?mica do Mycobacterium tuberculosis deu in?cio a uma nova era e foi de grande impacto para o presente conhecimento deste pat?geno como tamb?m na pesquisa de drogas anti-microbiais. Com estes avan?os foi poss?vel identificar genes e mais tarde validar vias metab?licas. O melhor entendimento das vias metab?licas presentes no Mycobacterium tuberculosis corresponde ao primeiro passo e configura uma possibilidade de identifica??o de novos alvos moleculares que possam erradicar o bacilo. Entretanto, ainda h? muito a fazer, desde a descoberta da Rifampicina, a droga de primeira linha efetivamente utilizada contra TB, nenhuma nova droga quimioter?pica foi identificada. Nos dias de hoje, a TB ? respons?vel pela morte de dois milh?es de pessoas por ano, sendo considerada uma emerg?ncia global, a qual precisa ser urgentemente erradicada. O presente projeto tem o objetivo de realizar a an?lise estrutural da enzima Citidina Deaminase (CDA; EC 3.5.4.5) de Mycobacterium tuberculosis associada com seus substratos e produtos, aliando t?cnicas de Din?mica e Docagem molecular.
Buzolin, Ricardo Henrique. "Mechanical properties and corrosion behaviours of the as-cast ZK40 alloys modified with individual additions of CaO, Gd, Nd and Y." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/18/18158/tde-13012017-093623/.
Повний текст джерелаO efeito da adição individual de óxido de cálcio (CaO), Gd, Nd e Y foi investigado na microestrutura, propriedades mecânicas e resistência à corrosão de ligas ZK40 fundidas. As características microestruturais foram analisadas via microscopia óptica, microscopia eletrônica de varredura, microscopia eletrônica de transmissão, difração de Raios-X e \"Scanning Kelvin Atomic Probe Force Microscopy\". O comportamento à compressão e à tração das ligas à temperatura ambiente foi investigado. Espectroscopia eletroquímica de impedância, evolução de hidrogênio e ensaios de imersão em solução de 0.5% em peso de NaCl foram utilizados para avaliar a resistência à corrosão. Os resultados dos ensaios mecânicos e corrosão foram relacionados com a microestrutura. A adição de 2% em peso de Gd melhorou a ductilidade, ao passo que a adição de Nd resultou na piora das propriedades mecânicas. A adição de 2% em peso de Gd e 1% em peso de Y resultou na melhora da ductilidade. A adição de 1% em peso de Y causou uma melhora na ductilidade e a adição de CaO não teve impacto benéfico nas propriedades mecânicas. A resistência à corrosão foi melhorada com a adição de CaO e Gd. A modificação da liga ZK40 com a adição de Gd abre novas perspectivas no desenvolvimento de ligas Mg-Zn.
Shokouhfar, Nasrin. "Synthèse et caractérisation de nouvelles armatures métal-organique à base de zirconium à partir de ligands carboxylates et étude de leur application dans l'adsorption et la détection des pollutions de l'eau et la capture et la conversion du CO2 et N2." Electronic Thesis or Diss., Université de Lille (2022-....), 2023. http://www.theses.fr/2023ULILN058.
Повний текст джерелаThis thesis investigates the synthesis and characterization of Zr-based metal-organic frameworks (MOFs) and their applications in water treatment and solar fuel production. MOFs are porous materials composed of metal ions and organic linkers that exhibit tuneable structures and functionalities. These properties make them suitable for various applications, such as gas storage, catalysis, sensing, drug delivery, etc.Water treatment is the process of removing contaminants from water to make it safe and clean for human use. One of the main contaminants in water are dyes, which are widely used in the textile, paper, and leather industries. Dye pollution can cause serious problems for aquatic life, human health, and aesthetic quality of water. To remove dyes from water, we synthesized a new Zr-MOF called TMU-66, which has a hollow sphere shape and an N-oxide functional group. TMU-66 can efficiently and selectively adsorb dye molecules through various interactions, such as electrostatic attraction, π-π stacking, and coordination bonding. TMU-66 exhibited and adsorption capacity of 472 mg/g for Congo red dye at pH 6.8 and 25 °C, one of the highest values achieved for MOF-based adsorbents so far.Solar fuel production is the process of converting solar energy into chemical fuels that can be stored and used later. One of the most promising fuels is ammonia (NH3), which can be produced from nitrogen (N2) and water (H2O) using sunlight as the energy source. This process is called N2 photoreduction or photocatalytic nitrogen fixation. However, this process is challenging because N2 is very stable and difficult to break apart. We modified another Zr-MOF called MOF-808 by adding a nitro group to its linker. The modified framework is able to absorb visible light and transfer electrons to N2 molecules. We also combined MOF-808/NIP with another material called g-C3N4, which can enhance light absorption and electron transfer. The resulting composite, MOF-808/NIP@g-C3N4, can produce up to 490 μmol ammonia per gram of composite per hour under visible light and ambient conditions.In summary, the objectives of this thesis work were to investigate the potential of MOFs for two distinct applications, utilizing a conceptual design approach that incorporated bandgap engineering, structure modulation, and heterojunction composite materials. The findings revealed that MOFs can absorb water impurities and function as photocatalysts to achieve ammonia production through solar-powered N2 photoreduction. This breakthrough has the potential to foster the creation of more effective and environmentally conscious technologies that tackle worldwide water pollution and ammonia production issues. These technologies are crucial in safeguarding our planet and guaranteeing a stable future
Brunel, Paul. "Complexes pince et cooperativité métal/ligand : application en catalyse." Thesis, Toulouse 3, 2018. http://www.theses.fr/2018TOU30275/document.
Повний текст джерелаThis Ph.D. work deals with organometallic chemistry of indenyl/indenediide palladium and platinum pincer complexes and their applications in metal-ligand cooperative catalysis. The first chapter of this manuscript compiled a non-exhaustive bibliographic survey of the field of metal-ligand cooperation, from Noyori's system applied to the asymmetric hydrogenation, to the recent examples described by Milstein involving non-aromatic pincer ligands. Pincer ligands are also presented. Starting from the first example, in which Shaw shed light a PCP pincer, to the contemporary CNC pincer reported by Bezuidenhout. The versatility of those ligands is illustrated through few modulations allowing originals reactivities or stabilisation of highly unstable species. The second chapter is focused on the development of a new catalytic reaction with the indenediide palladium pincer complex. This reaction entail, for the first time, two substrates, the CO2 as a C1 source and propargylamines/homopropargylamines. The mechanistic studies turn out the importance of the metal-ligand cooperativity. Then, the third chapter concerns exploratory chemistry. New reactivities have been studied with the platinum complexes. The activation of low polar bond such as H-H and H-Si allowed the reduction of unsatured C-C bond. The mechanistic propositions, that remain to be confirmed, seem to indicate the feasibility of ? bond metathesis and migratory insertions. Finally, the last chapter is dedicated to the development of a new ligand. The latter showed the distinctive characteristic to be hemilabile, leading the way of new reactivities. His coordination to palladium, followed by his deprotonation to give rise to the non-innocent nature of the complex is presented, as well as the application of the resulting complex in the context of a cycloisomerisation. Those results are reflecting the importance of the indenyl and indenediide pincer ligands besides the metal-ligand cooperativity in catalysis
Imolorhe, Ijeme. "FUNCTIONAL CHARACTERIZATION OF TWO PHENYLACETYL-COA LIGASES IN BURKHOLDERIA CENOCEPACIA." 2012. http://hdl.handle.net/1993/5081.
Повний текст джерелаAllina, Sandra Mary. "Phenylpropanoid metabolism in poplar : characterization of the 4-coumarate: CoA ligase gene family and a putative hydroxycinnamoyl-CoA thioesterase." Thesis, 1999. http://hdl.handle.net/2429/9827.
Повний текст джерелаHung, Mao-Sen, and 洪茂森. "Phylogeography of Abies kawakamii (Hayata) Ito based on 4-coumarate CoA ligase gene." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/76773225149029429005.
Повний текст джерела國立臺灣大學
植物科學研究所
92
Population genetic structure and phylogeographical relationships of Abies kawakamii (Hayata) Ito in Taiwan were studied by analyzing the DNA sequence of 4- coumarate CoA: ligase (4CL, 1174 bp). Samples were collected from eight alpine populations: Kuanshan, Yushan, Chilaishan, Hohuanshan, Nanhutashan, Tapachienshan, Tahsuenshan, and Wumingshan. Two clones of 4CL gene from each individual were sequenced. From a total of 135 DNA sequences of 68 individuals, 4CL can be separated into two gene family: 4CL1 and 4CL2. One of the gene, 4CL1 containing 88 sequences was further studied. The DNA fragment of 4CL1 consisted of five exons and four introns. The total length of intron was 380 bp, and contained 65 polymorphic sites: 60 point mutations and five insertions, giving a total of 71 haplotypes. The genealogical trees generated from these four introns showed similar pattern. Most of the sequences of each intron belonged to ancestral haplotype and derived haplotype, and many unique terminal haplotypes. Populations shared ancestral haplotype, derived haplotype, and the unique terminal haplotypes. These populations were retreating to higher altitude, experiencing an effect of bottleneck and genetic drift resulting in the composition of haplotype mentioned above that could characterize the refuge populations. Based on the average values of parameters of population differentiation, FST and KST, and population divergence DXY, we found that Tahsuenshan, Yushan, Wumingshan, and Chilaishan had the highest values indicating the possible major region of refugia for Abies kawakamii. According to 4CL1 DNA sequence and the morphology of seed, neither A. homolepis nor A. mariesii of Japan is ancestral to A. kawakamii. In terms of number of loci of 4CL1 gene, we found six loci among 16 in the gametophyte. These 4CL1 DNA sequences were very similar and only exhibited single nucleotide polymorphism.
Cukovic, Daniela. "Cloning and expression of genes encoding divergent 4-coumarate : CoA ligase in poplar." Thesis, 1999. http://hdl.handle.net/2429/9442.
Повний текст джерелаLaw, Adrienne. "Structural and functional characterization of PaaK1 & PaaK2: phenylacetate CoA ligase paralogs from Burkholderia cenocepacia J2315." Thesis, 2010. http://hdl.handle.net/1828/3613.
Повний текст джерелаGraduate
Rodriguez, Studart-Guimarães Claudia [Verfasser]. "Functional analysis of the role of succinyl CoA ligase in the photosynthetic metabolism of tomato / by Claudia Rodriguez Studart-Guimarães." 2006. http://d-nb.info/982292066/34.
Повний текст джерелаTsai, Hui-Ju, and 蔡蕙如. "Molecular Cloning and Expression of Resveratrol -related Biosynthesis of cinnamate 4-hydroxylase, 4-coumaroyl-CoA ligase and stilbene synthase from Vitis vinifera." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/w2q7dg.
Повний текст джерелаChien-Te, Ho, and 何建德. "Synthesis and Characterization of Coordination Polymers via the Self-assembly of Metal Ions (Co2+, Zn2+, Cd2+), Anionic Ligands (fumarate, isonicotinate, (+, -)tartrate) and Neutral Ligands (4,4-bipy, trans-bpe)." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/64329972598420078519.
Повний текст джерела國立中正大學
化學研究所
89
Seven novel organic-inorganic coordination polymers: Zn(fumarate)(4,4’-bipy)2 (1), [Co(4,4’-bipy)(H2O)4](fumarate)‧4H2O (2), Cd(fumarate)(4,4’-bipy) (3), Cd(isonicotinate)2(trans-bpe)0.5(H2O) (4), [Co(L(+)-tartrate)(4,4’-bipy)(H2O)]2‧(4,4’-bipy) (5) , [Co(D(-)-tartrate)(4,4’-bipy)(H2O)]2‧(4,4’-bipy) (6) and Cd3(NO3)2(isonicotinate)4(4,4’-bipy)2(H2O)2 (7) ( 4,4’-bipy = 4,4’-bipyridine, trans-bpe = trans-1,2-bis(4-pyridyl)-ethylene), were synthesized by pseudo -hydrothermal synthesis and characterized by X-ray crystallographic techniques. (1) crystallizes in monoclinic space group C2/c with a = 18.802(3) Å, b = 10.091(2) Å, c = 14.371(4) Å, β= 125.91(1)°,V = 2208.4(8) Å3. (2) crystallizes in triclinic space group P-1 with a = 7.060(1) Å, b =7.851(2) Å, c = 9.803(1) Å, α= 79.51(1)°, β= 86.63(1)°, γ= 72.59(2)°, V=507.5(2) Å3. (3) crystallizes in monoclinic space group C2/c with a =11.693(1) Å, b = 15.594(2) Å, c = 15.591(1) Å, β= 90.07(1)°, V = 2901.9(5) Å3. (4) crystallizes in triclinic space group P-1 with a = 9.647(1) Å, b = 9.664(1) Å, c = 11.143(2) Å, α= 104.79(1)°, β= 104.75(2)°, γ= 98.30(1)°, V=946.7(2) Å3. (5) crystallizes in monoclinic space group P21 with a = 11.4939(13) Å, b =9.6599(11) Å, c = 18.173(2) Å, β= 107.759(9)°, V = 1921.6(4) Å3. (6) crystallizes in monoclinic space group P21 with a = 11.495(2) Å, b = 9.6654(14) Å, c = 18.170(2) Å, β=107.724(10)°, V =1923.0(5) Å3. (7) crystallizes in monoclinic space group P21/n with a = 9.838(2) Å, b = 12.891(4) Å, c = 19.302(2) Å, β=90.57(2)°, V =2447.8(9) Å3. (1) consists of zigzag chains built up by [Zn(4,4’-bipy)2]2+ moieties linked by fumarate. The structure of (2) consists of one-dimensional chains built up by [Co(H2O)4]2+ units bridged by 4,4’-bipy, with one equivalent of fumarate located between the chains to balance the charge and four equivalents of uncoordinated water molecules. (3) adopts a three-dimensional framework, formed by Cd(fumarate) sheets cross-linked by 4,4’-bipy ligands. (4) is a three-dimensional framework, formed by [Cd(isonicotinate)2(H2O)] motifs cross-linked by 4,4’-bipy ligands. (5) and (6) are enantiomers, consisting of two-dimensional framework, formed by [Cd(tartrate)(H2O)] motifs linked by (4,4’-bipy) ligands, with one equivalent of uncoordinated 4,4’-bipy located between the two-dimensional framework. (7) has two Cd centers. Cd(1) is in a distorted pentagonal bipyrimidal coordination sphere while Cd(2) is in an octahedral environment. Cd(1) and Cd(2) are bridged by 4,4’-bipy and isonicotinate ligands, forming a three-dimensional framework. Their thermal stabilities and spectroscopic data are also reported in the thesis.