Дисертації з теми "CLUSTER VARIANCE"
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Akdemir, Deniz. "Components Of Response Variance For Cluster Samples." Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/1206044/index.pdf.
Повний текст джерелаYou, Zhiying. "Power and sample size of cluster randomized trials." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2009r/you.pdf.
Повний текст джерелаPark, Misook. "Design and Analysis Methods for Cluster Randomized Trials with Pair-Matching on Baseline Outcome: Reduction of Treatment Effect Variance." VCU Scholars Compass, 2006. http://hdl.handle.net/10156/2195.
Повний текст джерелаDunning, Allison. "Comparing Bootstrap and Jackknife Variance Estimation Methods for Area Under the ROC Curve Using One-Stage Cluster Survey Data." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/1849.
Повний текст джерелаRandriatsiferana, Rivo Sitraka A. "Optimisation énergétique des protocoles de communication des réseaux de capteurs sans fil." Thesis, La Réunion, 2014. http://www.theses.fr/2014LARE0019/document.
Повний текст джерелаTo increase the lifetime of wireless sensor networks, a solution is to improve the energy efficiency of the communication's protocol. The grouping of nodes in the wireless sensor network clustering is one of the best methods. This thesis proposes several improvements by changing the settings of the reference protocol LEACH. To improve the energy distribution of "cluster-heads", we propose two centralized clustering protocols LEACH and k-optimized version k-LEACH-VAR. A distributed algorithm, called e-LEACH, is proposed to reduce the periodic exchange of information between the nodes and the base station during the election of "cluster-heads". Moreover, the concept of energy balance is introduced in metric election to avoid overloading nodes. Then we presented a decentralized version of k-LEACH, which in addition to the previous objectives, integrates the overall energy consumption of the network. This protocol, called k-LEACH-C2D, also aims to promote the scalability of the network. To reinforce the autonomy and networks, both routing protocols "multi-hop" probability, denoted CB-RSM and FRSM build elementary paths between the "cluster-heads" and elected the base station. The protocol, CB-RSM, forms a hierarchy of "cluster-heads" during the training phase clusters, with an emphasis on self-scheduling and self-organization between "cluster-heads" to make the networks more scalable. These protocols are based on the basic idea that the nodes have the highest residual energy and lower variance of energy consumption become "cluster-head". We see the central role of consumption of the node in our proposals. This point will be the last part of this thesis. We propose a methodology to characterize experimentally the consumption of a node. The objectives are to better understand the consumption for different sequences of the node status. In the end, we propose a global model of the consumption of the node
Diaz, Acosta Beatriz. "Experiments in Image Segmentation for Automatic US License Plate Recognition." Thesis, Virginia Tech, 2004. http://hdl.handle.net/10919/9988.
Повний текст джерелаMaster of Science
Piana, Clause Fátima de Brum. "Regionalização para o cultivo do feijão no Rio Grande do Sul com base na interação genótipo x ambiente." Universidade Federal de Pelotas, 2009. http://repositorio.ufpel.edu.br/handle/ri/2081.
Повний текст джерелаIn Brazil, common bean (Phaseolus vulgaris L.) is cultivated in a range of ecologically differentiated environments. For being a culture highly influenced by the environment variation, its average productivity in the Country is unstable and low. An origin of this variation of productivity is the genotype x environment interaction, which has been one of the largest impediments for obtaining genotypes that maintain consistently high yield in the growing environments. The methods proposed for the exploration of the genotype x environment interaction are directed to the stability of the yield of the genotypes or to the regionalization of the growing locations. Most of the common bean genotypes registered for cultivation in Rio Grande do Sul evidences yield instability. The present research explored data from Rio Grande do Sul Common Bean State Trial ("Ensaio Estadual de Feijão" - EEF), executed at 24 locations in the period from 1987/88 to 1994/95, with considerable variation of genotypes and locations among those years. This research had two main objectives: (1) to evaluate the magnitude and the nature of the genotype x environment interaction and (2) to identify possible stratification of the growing region of common bean in the State in sub-regions inside of which the genotypes have stable relative performance. The inferences about the components of the interaction genotype x environment were proceeded by the joint analysis of each one of the eight years and the analyses of two subsets of four years and of the set of eight years. Because of the intent of obtaining a long time regionalization, general for the growing location of the Rio Grande do Sul and for any collection of beans genotypes, the factors year, location and genotype were considered random. The maximum likelihood and the generalized minimum squares methods were used. This approach allowed taking into account the incomplete and unbalanced structure of the data and the heterogeneity of variance of the experimental error. The results of the annual analyses revealed high significance of the component of the interaction genotype x location in all of the years, indicating that the relative performance of the genotypes varies among locations. This interaction was also revealed significant in the analysis of the eight years, but was not significant in the analyses of the two subsets four years. In these three joint analyses of years the triple interaction genotype x location x year was highly significant. The indication of heterogeneous performance of the genotypes among the locations and the possibility that the pattern of performance have some consistence along the years justified the attempt to the grouping of the locations. Cluster analyses were performed for each one of the eight years and for the set of eight years by the method of Sokal and Michener, that uses the Euclidean distance as similarity measure. The cluster analysis of the set of eight years constituted subregions that are generally incoherent with the sub-regions formed by the annual analyses that, by they turn, were inconsistent amongst themselves. This incoherence and inconsistency of groupings disabled the characterization of a division of the State for the regionalization of the indication of cultivars. It should be observed, however, that these evidences might have been influenced by the considerable alterations of the genotypes and of the locations of execution of the EEF among the years of the period from 1987/88 to 1994/95 in whose data they are based. They can also have resulted, partly, of flaws of the experimental techniques adopted in that period of execution of EEF, particularly of the accentuated variations of the sowing date and of the stand by plot.
No Brasil, o feijão (Phaseolus vulgaris L.) é cultivado em uma gama de ambientes ecologicamente diferenciados. Por ser uma cultura altamente influenciada pela variação de ambiente, sua produtividade média no país é instável e baixa. Uma origem da oscilação da produtividade é a interação genótipo x ambiente, a qual tem sido um dos maiores entraves para a obtenção de genótipos que mantenham rendimentos consistentemente elevados nos diversos ambientes de cultivo. Os métodos propostos para a exploração da interação genótipo x ambiente são direcionados para a estabilidade do rendimento dos genótipos ou para a regionalização dos locais de cultivo. A maioria dos genótipos de feijão registrados para cultivo no Rio Grande do Sul evidencia instabilidade de rendimento. A presente pesquisa explorou dados do Ensaio Estadual de Feijão (EEF) do Rio Grande do Sul, conduzido em 24 locais no período de 1987/88 a 1994/95, com variação considerável de genótipos e de locais entre esses anos. Essa pesquisa teve dois objetivos principais: (1) avaliar a magnitude e a natureza da interação genótipo x ambiente e (2) identificar possível estratificação da região de cultivo do feijão no Estado em sub-regiões dentro das quais os genótipos tenham desempenho relativo estável. As inferências sobre os componentes da interação genótipo x ambiente foram procedidas pela análise conjunta de cada um dos oito anos e as análises de dois subconjuntos de quatro anos e do conjunto dos oito anos. Em razão de se pretender lograr uma regionalização de longo prazo, geral para os locais de cultivo do Rio Grande do Sul e para qualquer coleção de genótipos de feijão, os fatores ano, local e genótipo foram considerados aleatórios. Foram utilizadas as metodologias de máxima verossimilhança e quadrados mínimos generalizados. Essa abordagem permitiu levar em conta a estrutura incompleta e não balanceada dos dados e a heterogeneidade da variância do erro experimental. Os resultados das análises anuais revelaram alta significância do componente da interação genótipo x local em todos os anos, indicando que o desempenho relativo dos genótipos se altera entre os locais. Essa interação também se revelou significativa na análise dos oito anos, mas não significativa nas análises dos dois subconjuntos de quatro anos. Nessas três análises conjuntas de anos a interação tripla genótipo x local x ano foi altamente significativa. A indicação de desempenho heterogêneo dos genótipos entre os locais e a possibilidade do padrão desse desempenho ter alguma consistência ao longo dos anos justificou a tentativa de agrupamento desses locais. Foram efetuadas análises de agrupamento para cada um dos oito anos e para o conjunto dos oito anos, pelo método de Sokal e Michener, que utiliza a distância euclidiana como medida de similaridade. A análise de agrupamento do conjunto dos oito anos constituiu sub-regiões incoerentes com as sub-regiões formadas pelas análises anuais que, por sua vez, foram inconsistentes entre si. Essa incoerência e inconsistência de agrupamentos impossibilitaram a caracterização de uma divisão do Estado para a regionalização da indicação de cultivares. Observe-se, entretanto, que essas evidências podem ter sido influenciadas pelas consideráveis alterações dos genótipos e dos locais de condução do EEF no período de 1987/88 a 1994/95 em cujos dados elas se baseiam. Também podem ter decorrido, em parte, de falhas das técnicas experimentais adotadas nesse período de execução do EEF, particularmente das acentuadas variações da data de semeadura e do estande por parcela.
Sartorio, Simone Daniela. "Aplicações de técnicas de análise multivariada em experimentos agropecuários usando o software R." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/11/11134/tde-06082008-172655/.
Повний текст джерелаThe use of the techniques of multivariate analysis is restricted to large centers of research, the higher companies and the academic environment. These techniques are very inte- resting because of the use of all answers variables simultaneously in theoretical interpretation of the data set, considering the correlations between them. One of the main obstacle to the usage of these techniques is that researchers interested in the quantitative research do not know them. The other di±culty is that most of the software that allow this type of analysis (SAS, MINITAB, BMDP, STATISTICA, S-PLUS, SYSTAT etc.) are not in public domain. Publishing the use of Multivariate techniques can improve the quality of the research, decrease the time spend and the cost, and make easy the interpretation of the structures of the data without cause damage of the information. In this report, were con¯rmed some advantages of the multivariate techniques in a univariate analysis for data of agricultural experiments. The analysis were taken with R software, a open software, \"friendly\" and free, with many statistical resources available.
Dimitrakopoulou, Vasiliki. "Bayesian variable selection in cluster analysis." Thesis, University of Kent, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.594195.
Повний текст джерелаRastelli, Riccardo, and Nial Friel. "Optimal Bayesian estimators for latent variable cluster models." Springer Nature, 2018. http://dx.doi.org/10.1007/s11222-017-9786-y.
Повний текст джерелаMcClelland, Robyn L. "Regression based variable clustering for data reduction /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/9611.
Повний текст джерелаOrr, Anton D. "Improving cluster analysis with automatic variable selection based on trees." Thesis, Monterey, California: Naval Postgraduate School, 2014. http://hdl.handle.net/10945/44639.
Повний текст джерелаClustering is an algorithmic technique that aims to group similar objects together in order to give users better understanding of the underlying structure of their data. It can be thought of as a two-step process. The first step is to measure the distances among the objects to determine how dissimilar they are. The second, clustering, step takes the dissimilarity measurements and assigns each object to a cluster. We examine three distance measures proposed by Buttrey at the Joint Statistical Meeting in Seattle, August 2006 based on classification and regression trees to address problems with determining dissimilarity. Current algorithms do not simultaneously address the issues of automatic variable selection, independence from variable scaling, resistance to monotonic transformation and datasets of mixed variable types. These "tree distances" are compared with an existing dissimilarity algorithm and two newer methods using four well-known datasets. These datasets contain numeric, categorical and mixed variable types. In addition, noise variables are added to test the ability of each algorithm to automatically select important variables. The tree distances offer much improvement for the problems they aimed to address, performing well against competitors amongst numerical datasets, and outperforming in the cases of categorical and mixed variable type datasets.
Olson, Christopher. "Entropy as a Criterion for Variable Reduction in Cluster Data." Thesis, North Dakota State University, 2012. https://hdl.handle.net/10365/26760.
Повний текст джерелаCall, Scott. "Long-Period Variable Stars in the Globular Cluster NGC 6553." Bowling Green State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1626973295690519.
Повний текст джерелаHodder, Philip Jeremy Crichton. "A search for faint variable stars in the globular cluster M71." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/28830.
Повний текст джерелаScience, Faculty of
Physics and Astronomy, Department of
Graduate
Weldrake, David Thomas Fredrick, and weldrake@mpia-hd mpg de. "Giant Planets and Variable Stars in Globular Clusters." The Australian National University. Research School of Astronomy and Astrophysics, 2005. http://thesis.anu.edu.au./public/adt-ANU20050616.191315.
Повний текст джерелаWeldrake, David Thomas Frederick. "Giant planets and variable stars in globular clusters /." View thesis entry in Australian Digital Theses Program, 2005. http://thesis.anu.edu.au/public/adt-ANU20050616.191315/index.html.
Повний текст джерелаSmitka, Michael Thomas. "Analysis of the Halo Globular Cluster M30 and its Variable Stars." Bowling Green State University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1182382804.
Повний текст джерелаPellegrin, Kyle S. "Long Period Variable Stars in the Globular Cluster M5 (NGC 5904)." Bowling Green State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1595605798891894.
Повний текст джерелаCameli, Cinzia <1988>. "Investigation of genetic risk variants for nicotine dependence and cluster headache." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amsdottorato.unibo.it/8583/1/Cinzia_Cameli_PhD_Thesis.pdf.
Повний текст джерелаAbdel-Rasoul, Mahmoud Hisham. "A Variance Estimator for Cohen’s Kappa under a Clustered Sampling Design." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1308329295.
Повний текст джерелаXue, Jianhong. "What drives a knowledge-based industry to cluster? : a latent variable analysis /." free to MU campus, to others for purchase, 2004. http://wwwlib.umi.com/cr/mo/fullcit?p1426116.
Повний текст джерелаKager, Elisabeth. "Pulsation Properties of Long Period Variable Stars in Globular Cluster NGC 6553." Bowling Green State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1277148078.
Повний текст джерелаCardona, Velasquez Gustavo Adolfo. "Properties of Bright Variable Stars in Unusual Metal Rich Cluster NGC 6388." Bowling Green State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1308577583.
Повний текст джерелаAl-Trad, Anas. "Optimized Composition of Parallel Components on a Linux Cluster." Thesis, Linköpings universitet, Institutionen för datavetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-86204.
Повний текст джерелаAbbas, Mohamad. "A search for Long-Period Variable Stars in the Globular Cluster NGC 6496." Bowling Green State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1308597257.
Повний текст джерелаHusband, Paul W. Jr. "Identification and Characterization of Long Period Variable Stars in the Globular Cluster M69." Bowling Green State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1499418711065308.
Повний текст джерелаDrury, Jason Andrew. "Observing variable stars and open clusters in the nominal Kepler superstamps." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/24143.
Повний текст джерелаIbberson, Mark Robert. "Genomic organisation and polymorphism of the human T cell receptor variable alpha gene cluster." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321749.
Повний текст джерелаLipkovich, Ilya A. "Bayesian Model Averaging and Variable Selection in Multivariate Ecological Models." Diss., Virginia Tech, 2002. http://hdl.handle.net/10919/11045.
Повний текст джерелаPh. D.
De, Marchi Fabrizio. "Variable stars and planetary transit search in super metal-rich open clusters." Doctoral thesis, Università degli studi di Padova, 2008. http://hdl.handle.net/11577/3427100.
Повний текст джерелаAljassim, Mohammad A. "A 6-Year Study of Long Period Variable Stars in the Globular Cluster NGC 6388." Bowling Green State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1499442952467274.
Повний текст джерелаMachin, Graham. "Cataclysmic variables in globular clusters and low mass X-ray binaries." Thesis, University of Oxford, 1990. http://ora.ox.ac.uk/objects/uuid:9cddbf39-034d-4d33-ad98-eecbe9bd60a7.
Повний текст джерелаJacunov, Vít. "Využití vícekriteriálního hodnocení variant pro obnovu (zajištění) serverové infrastruktury ve vybraném podniku." Master's thesis, Vysoká škola ekonomická v Praze, 2016. http://www.nusl.cz/ntk/nusl-203820.
Повний текст джерелаDean, Nema. "Variable selection and other extensions of the mixture model clustering framework /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/8943.
Повний текст джерелаAsvany, Oskar. "Experiments with Ions and Clusters in a variable temperature 22-pole ion trap." Doctoral thesis, Universitätsbibliothek Chemnitz, 2004. http://nbn-resolving.de/urn:nbn:de:swb:ch1-200400785.
Повний текст джерелаIm Rahmen dieser Arbeit wurden zwei Apparaturen mit 22-Pol-Ionenfallen benutzt, um protonierte Wassercluster H+(H2O)n (n=4..10) und kleine ionische Kohlenwasserstoffe CHn+ (n=2..5) bei tiefen Temperaturen zu untersuchen. Die in einer Koronaentladungsquelle erzeugten Cluster H+(H2O)n wurden kinetisch und spektroskopisch untersucht. Dazu wurden sie in einem 22-Pol-Speicher mithilfe eines He-Puffergases auf einer Temperatur zwischen 80K und 350K thermalisiert. Die Bestimmung der Bindungsenergien fuer Cluster der Groesse n=4..10 wird ermoeglicht durch die Messung der temperaturabhaengigen Dissoziationsraten und durch die Ermittlung der inneren Energien mittels berechneter Schwingungsfrequenzen. Temperaturabhaengige IR-Spektren im Bereich der freien OH-Streckschwingung wurden aufgenommen. Die Austausch- und Abstreifreaktionen von ionischen Kohlenwasserstoffen CHn+ (n=2..5) mit H2, HD und D2 und die darauffolgenden Assoziationsprozesse wurden im Temperaturbereich 15K bis 300K untersucht. Es stellt sich z.B. heraus, dass der H-D-Austauschprozess zwischen CH5+ und HD bei 15K sehr langsam ist, wogegen CH3+ mit jeder Kollision einen Austausch ausfuehrt. In der Abstreifreaktion von CH4+ mit Wasserstoffmolekuelen beobachtet man eine inverse Temperaturabhaengigkeit. Dies wird vorlaeufig mit einer laengeren Komplexlebensdauer bei tiefen Temperaturen erklaert
Barry, Amanda Nell. "Spectroscopic studies of the human copper chaperone for superoxide dismutase : probing the active cluster with selenocysteine variants." Full text open access at:, 2007. http://content.ohsu.edu/u?/etd,258.
Повний текст джерелаColman, Isabel Lily. "Pixels, photometry, and population studies: variable stars across four years of Kepler data." Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/22429.
Повний текст джерелаPeng, Wei. "Improving Nitrogen Management in Corn- Wheat-Soybean Rotations Using Site Specific Management in Eastern Virginia." Diss., Virginia Tech, 2001. http://hdl.handle.net/10919/29485.
Повний текст джерелаPh. D.
Aigner, Johanna 1981. "Genetical, structural and functional characterization of the human BTNL gene cluster." Doctoral thesis, Universitat Pompeu Fabra, 2013. http://hdl.handle.net/10803/127222.
Повний текст джерелаIn this thesis, we undertook a broad genomic, evolutionary, transcriptomic and functional analysis of a cluster containing three BTNL genes, namely BTNL8, BTNL3 and BTNL9, located on human chromosome 5q35.3. In the first chapter we report the identification of a 56 kb deletion copy number variant (CNV), which results in the formation of a novel chimeric gene, BTNL8*3, and leads to an upregulation in the expression-level of the third gene in the cluster, BTNL9. Next, we developed a genotyping assay and undertook a population analysis of this variant in several Hap Map and human diversity panel (HGDP-CEPH) populations. With this genotyping assay we could identify clear differences in the stratification of the BTNL8_BTNL3-del allele amongst major continental ethnic groups. In addition we report tagging SNPs in several population, facilitating the genotyping process of the BTNL8-BTNL3 deletion variant in the future. Moreover, we show an influence of the deletion CNV in the expression-level of several genes involved in cancer and immune response, suggesting an involvement of this CNV in specific biological pathways. In the second chapter we look for functional consequences of this CNV and found an upregulation of BTNL9 in acute lymphoblastic leukemia (ALL) after glucocorticoid (GC) treatment. Previously, it was shown that high-level BTNL9 correlates with high-risk in MLL-AF4 rearranged acute lymphoblastic leukemia (ALL) patients. To check whether this might be due to in involvement of BTNL9 in GC-induced apoptosis, we analyzed several pre-B ALL cell-lines and found a clear correlation between BTNL9 expression-level and resistance to GC in MLL rearranged ALL and at a lower level in MLL germ-line ALL. These results suggest a completely new and unexpected role for a BTNL protein and may led to the development of specific BTNL9 inhibitors to improve outcome of MLL rearranged ALL. Overall, we provide a comprehensive analysis of a BTNL gene cluster. We identified a new BTNL8*3 fusion-gene with potential implication in genetic pathways involved in immune regulation and proliferation, and show a clear function for BTNL9 in GC-resistance in MLL rearranged leukemia. This knowledge sheds more light on the BTNL family and may provide the basis for novel approaches using BTNL9 in MLL rearranged ALL therapy.
Hillwig, Todd C. "Analysis of the radial profile emissivity of accretion disks in cataclysmic variables." Virtual Press, 1995. http://liblink.bsu.edu/uhtbin/catkey/941346.
Повний текст джерелаLamertz, Larissa [Verfasser], and Jürgen [Gutachter] Scheller. "Klassisches, trans- und cluster-signaling durch HIL-6 und membrangebundene HIL-6 (mbHIL-6) Varianten und Identifizierung von neuen konstitutiven gp130 Varianten / Larissa Lamertz ; Gutachter: Jürgen Scheller." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2019. http://d-nb.info/1176806807/34.
Повний текст джерелаMilne, Peter. "The Variable Pronunciations of Word-final Consonant Clusters in a Force Aligned Corpus of Spoken French." Thèse, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31139.
Повний текст джерелаFiguera, Jaimes Roberto Jose. "High-precision time-domain astrophysics in crowded star-fields with ground based telescopes : globular clusters and the mitigation of the atmospheric turbulence." Thesis, University of St Andrews, 2018. http://hdl.handle.net/10023/13673.
Повний текст джерелаJohnson, Jay. "Identification of National Survey of Student Engagement (NSSE) socialization variable clusters that predict private midwestern college persistence." Diss., Columbia, Mo. : University of Missouri-Columbia, 2008. http://hdl.handle.net/10355/5513.
Повний текст джерелаThe entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on July 27, 2009) Includes bibliographical references.
Corradin, Olivia G. "Impact of DNA Variants in the Regulatory Circuitry of Gene Expression inHuman Disease." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1427988486.
Повний текст джерелаGomes, Kátia Regina Maruyama. "Padrão de expressão gênica e localização tecidual no rato de um novo membro do Cluster gênico da enzima conversora da angiotensina I: variante-4." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-28012009-162314/.
Повний текст джерелаThe renin-angiotensin system (RAS) is essential to maintain the cardiovascular homeostasis. The angiotensin-converting enzyme (ACE) is a critical point in the biochemical activation of several active substances, notably angiotensin II. Evidence obtained in our laboratory using comparative genomic analysis and confirmed by cDNA cloning suggests that this protein family is incomplete and point to the existence of two new isoforms of ACE that from now on are denominated Variant-3 (Var-3) and Variant-4 (Var-4), located within the same ACE locus. In the present work we simultaneously analyzed the expression pattern of the 4 ACE gene variants in 30 different tissues of rats. The variant 4, whose mechanism of action remains unknown and it is being presently investigated in our laboratory is mainly expressed in testis and in relatively low quantity in left ventricle. Using in situ hybridization technique in testis, we verified that positive labeling of Var-4 is distinct from Var-2, suggesting that they may play distinct functions during the spermatogenesis process. Taking together, we provide direct evidence that the ACE gene locus contain, 4 variants instead of 2 and they show a specific cell tissue pattern of expression. Mostly important, the Var-4 is primarily expressed in testis and the data suggest that it may be involved with spermatogenesis control, and in cardiac processes presently unknown
Azevedo, Bárbara Brzezinski. "Agrupamento de trabalhadores com perfis semelhantes de aprendizado utilizando técnicas multivariadas." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/96638.
Повний текст джерелаManufacturing of customized products relies on a large menu choice, reduced batch sizes and frequent alternation of tasks performed by workers. In this context, manual tasks are especially affected by workers’ adaptation to new product models. This learning process takes place in different paces within a group of workers. This thesis aims at grouping workers with similar learning process tailored to avoid bottlenecks in production lines due to learning dissimilarities among workers. For that matter, we present a method for clustering workers based on parameters derived from Learning Curve (LC) modeling. Such parameters are processed through Principal Component Analysis (PCA), and the PCA scores are used as clustering variables. Next, Kernel transformations are also used to improve clustering quality. The data is clustered using K-Means and Fuzzy C-Means techniques, and the quality of resulting clusters is measured by the Silhouette Index. Finally, we suggest a variable importance index based on parameters derived from PCA to select the most relevant variables for clustering. The proposed approaches are applied in a footwear process, yielding satisfactory results when compared to clustering on original data or without variable selection.
Gay, Emilie. "Détection d'agrégats spatiaux dans le cas d'une variable continue : application à un indicateur de l'infection mammaire chez les bovins." Clermont-Ferrand 1, 2006. http://www.theses.fr/2006CLF1MM03.
Повний текст джерелаCluster detection is an important field of investigation in epidemiology. Methods of cluster detection had mainly been developed for diseases described through dichotomic variables (case/control). But cattle intramammary infections are evaluated by the somatic cell score, a continuous variable expressing milk leukocyte count. Consequently, the thesis objective was to develop methods of spatial cluster detection, dealing with continuous variables, to analyse the spatial distribution of somatic cell score in French bovine dairy herds. The first approach developed, which is non parametric, is based on the Hellinger distance between spatial distributions. The measure of the distance between farm distribution, at different levels of somatic cell score, and the global farm density allowed to highlight a progressive concentration in some specific areas, and thus to detect clusters. The second approach, which is parametric, uses a model quantifying spatialised survival risk for increasing score levels. It integrates known risk factors for the cellular score, aswell as a "foci-effect" with a Gaussian form. The clusters detected with this method were the same as the ones highlighted by the method based on the Hellinger distance. The two methods are new flexible and generic tools for spatial cluster detection. They show several advantages : 1) they deal with diseases measured by continuous or discrete variables, 2) they account for known risk factors of the disease, and focus on unexplained clusters, and 3) they take into account the spatial heterogeneity of background population
ANGINO, SIRIA. "The importance of being clustered." Doctoral thesis, Luiss Guido Carli, 2017. http://hdl.handle.net/11385/201133.
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