Дисертації з теми "Chemokine"
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Hua, Renyi. "The role of chemokines/chemokine receptors in labour." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/9847.
Повний текст джерелаWong, Jeffrey K. W. "Chemokines and chemokine receptors in islet xenograft rejection." Thesis, The University of Sydney, 2006. https://hdl.handle.net/2123/28055.
Повний текст джерелаMowafi, Frida. "Chemokines and chemokine receptors during viral infections in man /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-420-4/.
Повний текст джерелаDavis, Christopher Nathan. "Mammalian and viral chemokines provide insight into the mechanism of chemokine receptor activation." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0006481.
Повний текст джерелаWang, Jixin. "Bioinformatic analysis of chicken chemokines, chemokine receptors, and Toll-like receptor 21." Texas A&M University, 2006. http://hdl.handle.net/1969.1/4212.
Повний текст джерелаTeleshova, Natalia. "Studies on co-stimulatory molecules, chemokines and chemokine receptors in neuroimmunological diseases /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4781-3/.
Повний текст джерелаMaru, Seema V. "The role of chemokines and chemokine receptors in astrocytes and astrocytoma biology." Thesis, Open University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427496.
Повний текст джерелаBrozyna, Sheree. "The role of chemokines and chemokine receptors in chronic obstructive pulmonary disease (COPD) /." Title page and abstract only, 2005. http://web4.library.adelaide.edu.au/theses/09SB/09sbb8859.pdf.
Повний текст джерелаSchweneker, Marc. "Identification and characterization of two novel proteins interacting with the chemokine- and HIV-1 co-receptor CCR5." [S.l.] : [s.n.], 2004. http://www.diss.fu-berlin.de/2004/22/index.html.
Повний текст джерелаFouillet, Antoine. "Cytokines regulation of chemokine and chemokine receptor in relation to multiple sclerosis." Thesis, Sheffield Hallam University, 2008. http://shura.shu.ac.uk/19675/.
Повний текст джерелаWaters, Victoria Hannah. "The chicken chemokine repertoire." Thesis, Royal Veterinary College (University of London), 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572437.
Повний текст джерелаLalani, Alshad Sadrudin. "Poxvirus chemokine binding proteins." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0019/NQ46868.pdf.
Повний текст джерелаRahimpour, Rahbar. "Regulation of chemokine and chemokine receptor expression and function during the inflammatory response." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0028/NQ31108.pdf.
Повний текст джерелаTopping, Joanna Ruth. "Regulation of circulating chemokine concentrations and bioactivity by glycosaminoglycans and chemokine binding proteins." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407377.
Повний текст джерелаMoyano, Clara. "Elucidating the signalling mechanisms of the CC chemokine receptor 5 upon chemokine stimulation." Thesis, University of East Anglia, 2011. https://ueaeprints.uea.ac.uk/33333/.
Повний текст джерелаSimmons, Graham. "Human immunodeficiency syndrome virus type 1 cell tropism and inhibition by chemokines and chemokine analogues." Thesis, Institute of Cancer Research (University Of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368041.
Повний текст джерелаGaspar, Maria Manuela Carvalho. "Expression of chemokine and chemokine receptor networks during rejection and induction of transplantation tolerance." Thesis, University of Oxford, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413973.
Повний текст джерелаCavalcante, GalylÃia Menezes. "Study of expression of systems CXCR4-CXCL12/SDF-1, CCR7-CCL21 and Ki-67 in the oral squamous cell carcinoma and their association with clinicopathological factors,nodal metastases and survival." Universidade Federal do CearÃ, 2013. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11989.
Повний текст джерелаAs quimiocinas sÃo citocinas quimiotÃticas responsÃveis pela migraÃÃo direcionada de leucÃcitos, coordenando o movimento celular durante a inflamaÃÃo e o transporte de cÃlulas hematopoiÃticas. AlÃm dos leucÃcitos, os receptores de quimiocinas tambÃm sÃo encontrados em cÃlulas neoplÃsicas e em tumores associados com cÃlulas estromais. Dentre as quimiocinas, os sistemas CXCR4/CXCL12 e CCR7/CCL21 tÃm sido demonstrado no envolvimento de metÃstases linfonodais ou à distÃncia em diferentes tipos de cÃncer. Dessa forma, foi objetivo desse trabalho avaliar a expressÃo de CXCR4, CXCL12, CCR7, CCL21 e Ki-67 em carcinoma de cÃlulas escamosas orais (CEC) e correlacionar estes marcadores com indicadores clÃnicopatolÃgicos, metÃstase linfonodal e sobrevida. Realizou-se um levantamento de laudos e blocos parafinados de biopsias excisionais de pacientes portadores de CEC tratados no Hospital Haroldo JuaÃaba (2001 a 2009). Foram coletados dados sobre localizaÃÃo anatÃmica da lesÃo, sexo, idade, sobrevida do paciente, grau de diferenciaÃÃo histopatolÃgica do tumor, estadiamento tumoral e presenÃa ou ausÃncia de metÃstase linfonodal, invasÃo linfovascular e perineural, grau nuclear e profundidade de invasÃo. Para reaÃÃo de imunohistoquÃmica, seguiu-se a tÃcnica da estreptavidina-biotina-peroxidase, utilizando os anticorpos anti-CXCR4, anti-CXCL12, anti-CCR7, anti-CCL21 e Ki-67. As secÃÃes histolÃgicas foram fotomicrografadas em 10 campos escolhidos aleatoriamente e quantificadas quanto ao nÃmero de cÃlulas tumorais marcadas e determinado o percentual de marcaÃÃo de cada anticorpo. A marcaÃÃo de CXCR4 foi detectada em citoplasma e nÃcleo, CXCL12, CCR7 e CCL21 tiveram marcaÃÃo apenas citoplasmÃtica, sendo observada suas expressÃes em 18 (60%), 8 (22,66%), 16 (53,3%) e 3 (12%) casos, respectivamente. Encontrou-se uma associaÃÃo significativa positiva entre a invasÃo linfovascular e a imunomarcaÃÃo do CXCR4 (p=0.007) e CCR7 (p=0.01) e dentre esses casos a metÃstase esteve presente em 62,5% e 37,5%, respectivamente. Quando em associaÃÃo com o Ki67, encontrou-se uma correlaÃÃo positiva significante entre o CXCR4 (p=0.0086), CXCL12 (p=0.036) e CCR7 (p=0.04). Dentre os pacientes CXCR4+, ao longo de 111 meses, apenas 38,4% estavam vivos (p=0.845), ao passo que tanto para pacientes CCR7+ (p = 0.398), quanto CXCR4+ e CCR7+ (p = 0.441), apÃs 62 meses, todos haviam ido a Ãbito. Conclui-se que essas quimiocinas estÃo associadas com a invasÃo linfovascular e proliferaÃÃo celular, talvez favorecendo o desenvolvimento de metÃstases e um pior prognÃstico.
Kanazawa, Nobuo. "Fractalkine and macrophage-derived chemokine : T cell attracting chemokines expressed in T cell area dendritic cells." Kyoto University, 2000. http://hdl.handle.net/2433/180886.
Повний текст джерелаEltayeb, Sana. "Chemokine receptor expression and function in experimental autoimmune neuroimflammation /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-197-5/.
Повний текст джерелаDalton, Richard S. J. "Chemokine and chemokine receptor gene expression in human PBMCs in the early renal post-transplant period." Thesis, University of Southampton, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.418008.
Повний текст джерелаSubileau, Eva-Anne. "Chemokine and chemokine receptor expression by human brain endothelium : an 'in vitro' and 'in situ' study." Thesis, Open University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434967.
Повний текст джерелаArnatt, Christopher Kent. "DEVELOPMENT OF ANTAGONISTS TARGETING CHEMOKINE RECEPTOR CCR5 AND THE CHEMOKINE RECEPTOR CCR5 – MU OPIOID RECEPTOR HETERODIMER." VCU Scholars Compass, 2013. http://scholarscompass.vcu.edu/etd/517.
Повний текст джерелаFranciszkiewicz, Katarzyna. "The role of chemokines and chemokine receptors in shaping the effector phase of anti-tumor immune response." Paris 7, 2010. http://www.theses.fr/2010PA077015.
Повний текст джерелаThe immune system-mediated eradication of cancer cells requires effector mechanisms associated with the presence of tumor-specific T cells. However, the successful generation of tumor-specific effector cells does not necessarily result in tumor regression. Cytotoxic T lymphocytes (CTL) must first be able to migrate to tumor sites, traverse the interstitial space and fmally interact with their target resulting in triggering of effector fonctions. Chemokines are involved in circulation of immunocompetent cells. Although some of them are known to contribute to tumor progression, others are responsible for changes in the tumor microenvironment that allow the infiltration of lymphocytes. In this study, we demonstrate that CTLs can be efficiently recruited into the tumor in a CCR5-dépendent manner. Once in the TGF-pl-rich autologous tumor site, they undergo an intratumoral adaptation process resulting in upregulation of the chemokine receptor CCR6 and the integrin aEß7 as well as the enhancement of T-cell receptor (TCR)-mediated cytotoxicity. The engagement of aEβ₇ leads to CCR5 recruitment at the IS and reduced T-cell responsiveness to a CCR5 ligand chemotactic gradient, suggesting a role of aEß7 in T-cell rétention at the tumor by a CCR5-dépendent mechanism. Altogether, these results show an important role of the chemokine/chemokine receptor network at multiple levels of CTL-mediated antitumor immune response. In consequence, the identification of chemokine-medjated molecular mechanisms can be important for the development of innovative immunotherapeutic approaches and may offer new opportunities to optimize existing protocols of cancer therapy
Law, Yuet Ching. "Specific Compartmentalization of IgA ASCs in Mouse Salivary Glands via Differential Expression of Chemokines and Chemokine Receptors." BYU ScholarsArchive, 2008. https://scholarsarchive.byu.edu/etd/1952.
Повний текст джерелаDobner, Bianca Carola [Verfasser]. "Chemokine bei Aderhautmelanomen / Bianca Carola Dobner." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2008. http://d-nb.info/1023232022/34.
Повний текст джерелаLanati, Silvia. "Chemokine-mediated metastasis in malignant melanoma." Thesis, University of Bristol, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.654112.
Повний текст джерелаMills, Shirley. "Chemokine signalling in malignant cell migration." Thesis, University of East Anglia, 2018. https://ueaeprints.uea.ac.uk/69973/.
Повний текст джерелаKhan, Abid. "CXCR4 chemokine receptor antagonists : new metallodrugs." Thesis, University of Hull, 2009. http://hydra.hull.ac.uk/resources/hull:10418.
Повний текст джерелаBarker, Catriona. "Modulation of chemokine function during inflammation." Thesis, University of Newcastle upon Tyne, 2014. http://hdl.handle.net/10443/2754.
Повний текст джерелаWavre, Silene Tuija. "Endocytic regulation of chemokine receptor expression." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1446114/.
Повний текст джерелаPetersen, Desiree C. "The role of chemokine and chemokine receptor genes in genetic susceptibility to HIV infection in South Africa." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/53158.
Повний текст джерелаEscher, Sylvia E. "Untersuchungen zur Struktur, Aktivitätsbeziehung des humanen CC-Chemokins HCC-2." [S.l.] : [s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=958876290.
Повний текст джерелаCornelissen, Gesine. "Integrierte Bioprozessentwicklung zur Herstellung pharmakologischer wirksamer Proteine mit Pichia pastoris /." Düsseldorf : VDI-Verl, 2004. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=012990697&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Повний текст джерелаNüßeler, Elke. "Charakterisierung des Chemokinrezeptor-ähnlichen orphan-Rezeptors CXCR1-like der Maus." [S.l. : s.n.], 2006. http://nbn-resolving.de/urn:nbn:de:bsz:289-vts-55569.
Повний текст джерелаPopović, Milan. "Expression and function of thrombin receptors (PAR1, PAR3 and PAR4) in human umbilical vein endothelial cells: thrombin-mediated CX3CL1 expression." [S.l. : s.n.], 2008. http://nbn-resolving.de/urn:nbn:de:bsz:289-vts-63323.
Повний текст джерелаThapa, Manoj. "Chemokines and chemokine receptors that mediate immune defense to genital herpes simplex virus type 2 (HSV-2) infection." Oklahoma City : [s.n.], 2008.
Знайти повний текст джерелаDuchesnes, Cecile Emmanuelle. "Molecular characterisation of the chemokine receptor CCR3." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407171.
Повний текст джерелаMartinelli, Roberta. "Molecular characterisation of the chemokine receptor CCR2." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398841.
Повний текст джерелаWilson, Shirley Risk. "Oligomerisation of chemokine receptors CXCR1 and CXCR2." Thesis, University of Glasgow, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.418346.
Повний текст джерелаSherwood, Joanna. "ELR+ CXC chemokine signalling in cartilage homeostasis." Thesis, Queen Mary, University of London, 2011. http://qmro.qmul.ac.uk/xmlui/handle/123456789/2447.
Повний текст джерелаCAGLIANI, ROBERTA. "NANOBIOINTERACTIONS: CHEMOKINE MEDIATED SELECTIVE TARGETING OF NANOPARTICLES." Doctoral thesis, Università degli studi di Genova, 2020. http://hdl.handle.net/11567/1000880.
Повний текст джерелаKhan, Nouman Ullah. "The effect of chemokines on T regulatory cells following heart transplantation." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/the-effect-of-chemokines-on-t-regulatory-cellsfollowing-heart-transplantation(6b5b194d-f2fd-4869-9b22-95ce099ac3ed).html.
Повний текст джерелаJansma, Ariane L. "Structural and functional analysis of the chemokine CCL27 and the expression and purification of silent chemokine receptors D6 and DARC." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p3386768.
Повний текст джерелаTitle from first page of PDF file (viewed February 4, 2010). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 196-206).
González, Motos Víctor [Verfasser]. "Discovery and characterization of a novel chemokine binding protein of varicella zoster virus that enhances chemokine activity / Víctor González Motos." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2017. http://d-nb.info/1150192194/34.
Повний текст джерелаMcClure, Charles Patrick. "HIV-1 in the genital tract." Thesis, University of Nottingham, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275163.
Повний текст джерелаLipfert, Jana. "Die Rolle und Funktionsweise der Chemokinrezeptoren CXCR4 und CXCR7 in Mikroglia und Astrozyten." Doctoral thesis, Universitätsbibliothek Leipzig, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-118858.
Повний текст джерелаChu, Sok-fan. "Association between [beta]-Chemokine gene polymorphisms and tuberculosis." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B35736136.
Повний текст джерелаBöcker, Sophia. "GPI-verankerte Chemokine als Adjuvantien in der Tumortherapie." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-158566.
Повний текст джерелаMillette, Roxanne. "The effect of chemokine CCL19 on B lymphocytes /." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=79051.
Повний текст джерела