Книги з теми "Cellular RNAs"

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1

Mallick, Bibekanand. Regulatory RNAs: Basics, Methods and Applications. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012.

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2

Pitre, Liisa K. The application of RNA interference to cellular biotechnology. Sudbury, Ont: Laurentian University, 2003.

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3

Brasier, Allan R., Adolfo García-Sastre, and Stanley M. Lemon, eds. Cellular Signaling and Innate Immune Responses to RNA Virus Infections. Washington, DC, USA: ASM Press, 2008. http://dx.doi.org/10.1128/9781555815561.

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4

R, Brasier Allan, García-Sastre Adolfo, and Lemon Stanley M, eds. Cellular signaling and innate immune responses to RNA virus infections. Washington, D.C: ASM Press, 2009.

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5

Kekkonen, Viktoria. Characterization of bacterial RNA and DNA signalling pathways that induce cellular dysfunction. Sudbury, Ont: Laurentian University, 2006.

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6

Post-transcriptional regulation by STAR proteins : control of RNA metabolism in development and disease. New York: Springer Science+Business Media, LLC, 2010.

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7

Yechiel, Becker, and Darai Gholamreza, eds. Molecular evolution of viruses-past and present: Evolution of viruses by acquisition of cellular RNA and DNA. Boston: Kluwer Academic Publishers, 2000.

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8

Wingender, Edgar. Gene regulation in eukaryotes. Weinheim: VCH, 1993.

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9

Jeffrey, Wilusz, ed. Post-transcriptional gene regulation. Totowa, N.J: Humana Press, 2008.

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10

Farrell, Robert E. RNA methodologies: A laboratory guide for isolation and characterization. San Diego: Academic Press, 1993.

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11

Farrell, Robert E. RNA methodologies: A laboratory guide for isolation and characterization. 2nd ed. San Diego: Academic Press, 1998.

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12

RNA methodologies: A laboratory guide for isolation and characterization. 3rd ed. Amsterdam: Elsevier/Focal Press, 2005.

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13

Tax, Frans. Receptor-like Kinases in Plants: From Development to Defense. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012.

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14

D, Rickwood, and Hames B. D, eds. Gel electrophoresis of nucleic acids: A practical approach. Oxford: IRL Press, 1987.

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15

M, Zborowski, and Chalmers J. J, eds. Magnetic cell separation. Amsterdam: Elsevier, 2008.

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16

Van Regenmortel, M. H. V., ed. Synthetic polypeptides as antigens. Amsterdam: Elsevier, 1988.

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17

Divan, Aysha, and Janice A. Royds. 3. RNA. Oxford University Press, 2016. http://dx.doi.org/10.1093/actrade/9780198723882.003.0003.

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Анотація:
The first RNA molecules to be discovered were those involved in protein synthesis, mRNA, transfer RNA (tRNA), and ribosomal RNA (rRNA). In recent years, a vast number of additional RNA molecules have been identified. ‘RNA’ explains that these are non-coding RNAs that are not involved in protein synthesis, but influence many normal cellular and disease processes by regulating gene expression. RNA interference (RNAi) as one of the main ways in which gene expression is regulated is described with applications to therapy. Classes of RNA, including long non-coding RNAs and catalytic RNAs, are explained along with RNA techniques used to study RNA molecule and gene function.
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18

Mallick, Bibekanand, and Zhumur Ghosh. Regulatory RNAs: Basics, Methods and Applications. Springer, 2014.

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19

Mallick, Bibekanand, and Zhumur Ghosh. Regulatory RNAs: Basics, Methods and Applications. Springer, 2012.

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20

Reckman, Yolan J., and Yigal M. Pinto. The role of non-coding RNA/microRNAs in cardiac disease. Edited by José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, José Luis de la Pompa, David Sedmera, Cristina Basso, and Deborah Henderson. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0031.

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Анотація:
In the past two decades, our knowledge about non-coding DNA has increased tremendously. While non-coding DNA was initially discarded as ‘junk DNA’, we are now aware of the important and often crucial roles of RNA transcripts that do not translate into protein. Non-coding RNAs (ncRNAs) play important functions in normal cellular homeostasis and also in many diseases across all organ systems. Among the different ncRNAs, microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) have been studied the most. In this chapter we discuss the role of miRNAs and lncRNAs in cardiac disease. We present examples of miRNAs with fundamental roles in cardiac development (miR-1), hypertrophy (myomiRs, miR-199, miR-1/133), fibrosis (miR-29, miR-21), myocardial infarction (miR-15, miR17~92), and arrhythmias/conduction (miR-1). We provide examples of lncRNAs related to cardiac hypertrophy (MHRT, CHRF), myocardial infarction (ANRIL, MIAT), and arrhythmias (KCNQ1OT1). We also discuss miRNAs and lncRNAs as potential therapeutic targets or biomarkers in cardiac disease.
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21

Cellular RNA Interference Mechanisms. Elsevier, 2011. http://dx.doi.org/10.1016/c2011-0-04281-3.

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22

Grimm, Dirk. Cellular RNA Interference Mechanisms. Elsevier Science & Technology Books, 2011.

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23

Grimm, Dirk. Cellular RNA Interference Mechanisms. Elsevier Science & Technology Books, 2011.

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24

Masquida, Benoît, and Fabrice Leclerc. Looking at Ribozymes: From Atomic to Molecular and Cellular Scales. Elsevier, 2019.

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25

Masquida, Benoît, and Fabrice Leclerc. Looking at Ribozymes: From Atomic to Molecular and Cellular Scales. Elsevier, 2019.

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26

Gunaratne, Preethi, and Matthew L. Anderson. MicroRNAs in Health and Disease. Taylor & Francis Group, 2014.

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27

Lemon, Stanley M., Allan R. Brasier, and Adolfo Garcia-Sastre. Cellular Signaling and Innate Immune Responses to RNA Virus Infections. Wiley & Sons, Limited, John, 2014.

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28

Becker, Yechiel. Replication of Viral and Cellular Genomes: Molecular Events at the Origins of Replication and Biosynthesis of Viral and Cellular Genomes. Springer, 2011.

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29

Replication of Viral and Cellular Genomes: Molecular events at the origins of replication and biosynthesis of viral and cellular genomes. Springer, 2011.

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30

Becker, Yechiel. Replication of Viral and Cellular Genomes: Molecular Events at the Origins of Replication and Biosynthesis of Viral and Cellular Genomes. Springer London, Limited, 2012.

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31

Roles and Functions of ROS and RNS in Cellular Physiology and Pathology. MDPI, 2020. http://dx.doi.org/10.3390/books978-3-03928-783-3.

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32

Erickson, Robert P. Gene Regulation: Biology of Antisense Rna and DNA (Raven Press Series on Molecular and Cellular Biology). Raven Pr, 1991.

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33

Becker, Yechiel. Molecular Evolution of Viruses - Past and Present: Evolution Of Viruses By Acquisition Of Cellular Rna And Dna. Springer, 2012.

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34

Becker, Yechiel, and Gholamreza Darai. Molecular Evolution of Viruses -- Past and Present: Evolution of Viruses by Acquisition of Cellular RNA and DNA. Springer London, Limited, 2012.

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35

Molecular biology of RNA: Proceedings of a Director's Sponsors-UCLA Symposium, held at Keystone, Colorado, April 4-10, 1988 (UCLA symposia on molecular and cellular biology). Liss, 1989.

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36

Hughes, Alis, and Lesley Jones. Pathogenic Mechanisms. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199929146.003.0013.

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Анотація:
Huntington’s disease (HD) pathogenesis is complex. In the two decades since the gene and its mutation were discovered, there has been extensive exploration of how the expanded CAG repeat in HTT leads to neurodegeneration in HD. This chapter focuses on the mechanisms that potentially contribute to the dysfunction and death of cells in HD. These include repeat instability and RNA toxicity and the production, processing, modification, and degradation of mutant huntingtin. The effects of mutant HTT on cellular processes such as transcription, transport, neurotransmission, and protein clearance are also described. The interdependence and individual importance of these mechanisms in disease etiology remains to be clarified; however, consideration of each could be important for the development of therapeutic interventions in HD.
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37

(Editor), Y. Becker, and Gholamreza Darai (Editor), eds. Molecular Evolution of Viruses - Past and Present: Evolution of Viruses by Acquisition of Cellular RNA and DNA (VIRUS GENES). Springer, 2007.

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38

Webster, Jessica Lynn, and Marco Vignuzzi. Viral evolution and impact for public health strategies in low-income countries. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198789833.003.0007.

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Анотація:
Viruses, the simplest organisms, obligate parasites that encode structural proteins and replicative functions requiring the cellular machinery of the host to ensure their propagation. Viruses are masters of evolution. An analysis of infectious diseases emerging since the 1980s revealed that most were caused by viruses, especially those with RNA genomes. New viral emergences are generally the result of intrinsic changes in the genetics of the virus to increase transmission, virulence or host range, and environmental or ecological changes that favor contacts between viruses and humans or other hosts. We describe the molecular mechanisms of viruses that ensure their rapid adaptation and evolution. We describe instances where viral evolution appears partially responsible for recent outbreaks and discuss the challenges in identifying the cause or consequence of viral evolution in the context of resource-rich versus -limited countries.
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39

Vaheri, Antti, James N. Mills, Christina F. Spiropoulou, and Brian Hjelle. Hantaviruses. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0035.

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Анотація:
Hantaviruses (genus Hantavirus, family Bunyaviridae) are rodent- and insectivore-borne zoonotic viruses. Several hantaviruses are human pathogens, some with 10-35% mortality, and cause two diseases: hemorrhagic fever with renal syndrome (HFRS) in Eurasia, and hantavirus cardiopulmonary syndrome (HCPS) in the Americas. Hantaviruses are enveloped and have a three-segmented, single-stranded, negative-sense RNA genome. The L gene encodes an RNA-dependent RNA polymerase, the M gene encodes two glycoproteins (Gn and Gc), and the S gene encodes a nucleocapsid protein. In addition, the S genes of some hantaviruses have an NSs open reading frame that can act as an interferon antagonist. Similarities between phylogenies have suggested ancient codivergence of the viruses and their hosts to many authors, but increasing evidence for frequent, recent host switching and local adaptation has led to questioning of this model. Infected rodents establish persistent infections with little or no effect on the host. Humans are infected from aerosols of rodent excreta, direct contact of broken skin or mucous membranes with infectious virus, or rodent bite. One hantavirus, Andes virus, is unique in that it is known to be transmitted from person-to-person. HFRS and HCPS, although primarily affecting kidneys and lungs, respectively, share a number of clinical features, such as capillary leakage, TNF-, and thrombocytopenia; notably, hemorrhages and alterations in renal function also occur in HCPS and cardiac and pulmonary involvement are not rare in HFRS. Of the four structural proteins, both in humoral and cellular immunity, the nucleocapsid protein appears to be the principal immunogen. Cytotoxic T-lymphocyte responses are seen in both HFRS and HCPS and may be important for both protective immunity and pathogenesis. Diagnosis is mainly based on detection of IgM antibodies although viral RNA (vRNA) may be readily, although not invariably, detected in blood, urine and saliva. For sero/genotyping neutralization tests/RNA sequencing are required. Formalin-inactivated vaccines have been widely used in China and Korea but not outside Asia. Hantaviruses are prime examples of emerging and re-emerging infections and, given the limited number of rodents and insectivores thus far studied, it is likely that many new hantaviruses will be detected in the near future.
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40

Wilusz, Jeffrey. Post-Transcriptional Gene Regulation. Humana Press, 2010.

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41

Post-Transcriptional Gene Regulation. Humana Press, 2007.

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42

Short And Long Distance Signaling. Springer, 2011.

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43

Methylation, Hoffmann-LA Roche-UCLA Colloquium on Nucleic Acid, Dawn B. Willis, Arthur Weissbach, and Gary A. Clawson. Nucleic Acid Methylation: Proceedings of a Hoffman-LA Roche-UCLA Colloquium on Nucleic Acid Methylation Held at Frisco, Colorado, March 31-April 7, (Ucla ... and Cellular Biology, New Ser., V. 128). Wiley-Liss, 1989.

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44

Benarroch, Eduardo E. Neuroscience for Clinicians. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190948894.001.0001.

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Анотація:
The aim of this book is to provide the clinician with a comprehensive and clinical relevant survey of emerging concepts on the organization and function of the nervous system and neurologic disease mechanisms, at the molecular, cellular, and system levels. The content of is based on the review of information obtained from recent advances in genetic, molecular, and cell biology techniques; electrophysiological recordings; brain mapping; and mouse models, emphasizing the clinical and possible therapeutic implications. Many chapters of this book contain information that will be relevant not only to clinical neurologists but also to psychiatrists and physical therapists. The scope includes the mechanisms and abnormalities of DNA/RNA metabolism, proteostasis, vesicular biogenesis, and axonal transport and mechanisms of neurodegeneration; the role of the mitochondria in cell function and death mechanisms; ion channels, neurotransmission and mechanisms of channelopathies and synaptopathies; the functions of astrocytes, oligodendrocytes, and microglia and their involvement in disease; the local circuits and synaptic interactions at the level of the cerebral cortex, thalamus, basal ganglia, cerebellum, brainstem, and spinal cord transmission regulating sensory processing, behavioral state, and motor functions; the peripheral and central mechanisms of pain and homeostasis; and networks involved in emotion, memory, language, and executive function.
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45

Schiessel, Helmut. Biophysics for Beginners: A Journey Through the Cell Nucleus. Jenny Stanford Publishing, 2021.

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46

Schiessel, Helmut. Biophysics for Beginners: A Journey Through the Cell Nucleus. Pan Stanford Publishing, 2013.

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47

Schiessel, Helmut. Biophysics for Beginners: A Journey Through the Cell Nucleus. Pan Stanford Publishing, 2013.

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48

Schiessel, Helmut. Biophysics for Beginners. Taylor & Francis Group, 2021.

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49

Signal Transduction: Pathways, Mechanisms and Diseases. Springer, 2009.

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50

Kemmerling, Birgit, and Frans Tax. Receptor-like Kinases in Plants: From Development to Defense. Springer, 2014.

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