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Статті в журналах з теми "Cell autonomy"

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Автор: Grafiati

Опубліковано: 10 грудня 2022

Оновлено: 28 січня 2023

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1

Piccirillo, Sarah, Andrew P. Morgan, Andy Y. Leon, Annika L. Smith, and Saul M. Honigberg. "Investigating cell autonomy in microorganisms." Current Genetics 68, no. 2 (February 4, 2022): 305–18. http://dx.doi.org/10.1007/s00294-022-01231-5.

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2

Chigira, M., K. Noda, and H. Watanabe. "Autonomy in tumor cell proliferation." Medical Hypotheses 32, no. 4 (August 1990): 249–54. http://dx.doi.org/10.1016/0306-9877(90)90101-j.

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3

Nashmi, Raad, and Henry Lester. "Cell autonomy, receptor autonomy, and thermodynamics in nicotine receptor up-regulation." Biochemical Pharmacology 74, no. 8 (October 2007): 1145–54. http://dx.doi.org/10.1016/j.bcp.2007.06.040.

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4

Leptin, M., and S. Roth. "Autonomy and non-autonomy in Drosophila mesoderm determination and morphogenesis." Development 120, no. 4 (April 1, 1994): 853–59. http://dx.doi.org/10.1242/dev.120.4.853.

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The mesoderm in Drosophila invaginates by a series of characteristic cell shape changes. Mosaics of wild-type cells in an environment of mutant cells incapable of making mesodermal invaginations show that this morphogenetic behaviour does not require interactions between large numbers of cells but that small patches of cells can invaginate independent of their neighbours' behaviour. While the initiation of cell shape change is locally autonomous, the shapes the cells assume are partly determined by the individual cell's environment. Cytoplasmic transplantation experiments show that areas of cells expressing mesodermal genes ectopically at any position in the egg form an invagination. We propose that ventral furrow formation is the consequence of all prospective mesodermal cells independently following their developmental program. Gene expression at the border of the mesoderm is induced by the apposition of mesodermal and non-mesodermal cells.

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5

Welsh, David K., Joseph S. Takahashi, and Steve A. Kay. "Suprachiasmatic Nucleus: Cell Autonomy and Network Properties." Annual Review of Physiology 72, no. 1 (March 17, 2010): 551–77. http://dx.doi.org/10.1146/annurev-physiol-021909-135919.

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6

Albertini, David F. "The non-cell autonomy of human gametes." Journal of Assisted Reproduction and Genetics 35, no. 2 (February 2018): 189–90. http://dx.doi.org/10.1007/s10815-018-1139-z.

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7

Sugihara, Kei, Koichi Nishiyama, Shigetomo Fukuhara, Akiyoshi Uemura, Satoshi Arima, Ryo Kobayashi, Alvaro Köhn-Luque, et al. "Autonomy and Non-autonomy of Angiogenic Cell Movements Revealed by Experiment-Driven Mathematical Modeling." Cell Reports 13, no. 9 (December 2015): 1814–27. http://dx.doi.org/10.1016/j.celrep.2015.10.051.

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8

Darbas, Aysel, Martine Jaegle, Erik Walbeehm, Hans van den Burg, Siska Driegen, Ludo Broos, Matthijs Uyl, Pim Visser, Frank Grosveld, and Dies Meijer. "Cell autonomy of the mouse claw paw mutation." Developmental Biology 272, no. 2 (August 2004): 470–82. http://dx.doi.org/10.1016/j.ydbio.2004.05.017.

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9

Fuerst, Peter G., Freyja Bruce, Ryan P. Rounds, Lynda Erskine, and Robert W. Burgess. "Cell autonomy of DSCAM function in retinal development." Developmental Biology 361, no. 2 (January 2012): 326–37. http://dx.doi.org/10.1016/j.ydbio.2011.10.028.

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10

Lemaire, Patrick, Nigel Garrett, and J. B. Gurdon. "Autonomy and cell communication in amphibian mesoderm formation." Biology of the Cell 84, no. 1-2 (1995): 86. http://dx.doi.org/10.1016/0248-4900(96)81332-3.

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11

Kim, Dong-il. "Anarchism, Autonomy, and Peace." Korean Review of Political Thought 28, no. 2 (November 30, 2022): 106–31. http://dx.doi.org/10.37248/krpt.2022.11.28.2.106.

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12

Gallagher, Emily J. "Signal autonomy: Skeletal muscle in diabetes." Science Translational Medicine 12, no. 563 (September 30, 2020): eabe6026. http://dx.doi.org/10.1126/scitranslmed.abe6026.

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13

Welsh, David K. "Limits of single-cell autonomy in the suprachiasmatic nucleus." Sleep and Biological Rhythms 7, no. 4 (October 2009): 252–59. http://dx.doi.org/10.1111/j.1479-8425.2009.00425.x.

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14

Mohawk, Jennifer A., and Joseph S. Takahashi. "Cell autonomy and synchrony of suprachiasmatic nucleus circadian oscillators." Trends in Neurosciences 34, no. 7 (July 2011): 349–58. http://dx.doi.org/10.1016/j.tins.2011.05.003.

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15

Lynch, Holley E., Jim Veldhuis, G. Wayne Brodland, and M. Shane Hutson. "Modeling cell elongation during germ band retraction: cell autonomy versus applied anisotropic stress." New Journal of Physics 16, no. 5 (May 6, 2014): 055003. http://dx.doi.org/10.1088/1367-2630/16/5/055003.

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16

Technau, G. M., and J. A. Campos-Ortega. "Cell autonomy of expression of neurogenic genes of Drosophila melanogaster." Proceedings of the National Academy of Sciences 84, no. 13 (July 1, 1987): 4500–4504. http://dx.doi.org/10.1073/pnas.84.13.4500.

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17

Ripoll, Pedro, and James A. Kennison. "Cell autonomy of two DNA-repair mutations in Drosophila melanogaster." Genetical Research 46, no. 1 (August 1985): 31–44. http://dx.doi.org/10.1017/s0016672300022436.

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SUMMARYBy means of genetic mosaics we have studied the cell autonomy of mei-41 and mei-9, two loci involved in DNA metabolism. The frequency of spontaneous somatic spots resulting from unrepaired chromosome damage and the sensitivity of mutant cells to killing by X-irradiation - two traits indicative of deficient DNA repair - have been analysed at the cellular level. The results show that: (1) The effect of both mutations on chromosome stability is cell autonomous. (2) After 1000 r of X-irradiation practically all the cells homozygous for mei-41 disappear while about one-third of the cells homozygous for mei-9a survive the irradiation. The possibility of using these mutants as tools to approach developmental problems is discussed.

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18

Bagnard, D. "The autonomy of axons: no need for a cell body." Trends in Cell Biology 12, no. 10 (October 1, 2002): 458. http://dx.doi.org/10.1016/s0962-8924(02)02374-7.

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19

Seydoux, Geraldine, and Iva Greenwald. "Cell autonomy of lin-12 function in a cell fate decision in C. elegans." Cell 57, no. 7 (June 1989): 1237–45. http://dx.doi.org/10.1016/0092-8674(89)90060-3.

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20

Paiva, Rafael A., Camila V. Ramos, and Vera C. Martins. "Thymus autonomy as a prelude to leukemia." FEBS Journal 285, no. 24 (September 17, 2018): 4565–74. http://dx.doi.org/10.1111/febs.14651.

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21

Neuner, B., A. Dizner-Golab, LM Gentilello, B. Habrat, E. Mayzner-Zawadzka, A. Górecki, E. Weiss-Gerlach, et al. "Trauma Patients' Desire for Autonomy in Medical Decision Making is Impaired by Smoking and Hazardous Alcohol Consumption – a Bi-national Study." Journal of International Medical Research 35, no. 5 (September 2007): 609–14. http://dx.doi.org/10.1177/147323000703500505.

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This cross-sectional investigation studied the association between substance use and patients' desire for autonomy in medical decision making (MDM) in two trauma settings. A total of 102 patients (age 42.7 ≤ 17.4 years, 70.6% male) admitted to an orthopaedic service in Warsaw, Poland, and 1009 injured patients (age 34.6 ≤ 12.8 years, 62.3% male) treated in an emergency department in Berlin, Germany, were enrolled. Patients' desire for autonomy in MDM was evaluated with the Decision Making Preference Scale of the Autonomy Preference Index. Substance use (hazardous alcohol consumption and/or tobacco use) and educational level were measured. Linear regression techniques were used to determine the association between substance use and desire for autonomy in MDM. Substance use was found to be independently associated with a reduced desire by the patient for autonomy in medical decision making. No differences in patients' desire for autonomy were observed between the study sites. Empowerment strategies that encourage smokers or patients with hazardous alcohol consumption to participate in MDM may increase the effectiveness of health promotion and injury prevention efforts in this population.

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22

Heath, I. B., S. G. Kaminskyj, and T. Bauchop. "Basal body loss during fungal zoospore encystment: evidence against centriole autonomy." Journal of Cell Science 83, no. 1 (July 1, 1986): 135–40. http://dx.doi.org/10.1242/jcs.83.1.135.

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The controversial question of the possible autonomy of centrioles, as shown by the persistence of all or part of them in the generative cell line throughout the life cycle of organisms, remains unresolved. All previous reports on shedding or withdrawal of cilia and flagella showed that their basal bodies (= centrioles) were retained in the cells where they may, or may not, subsequently disassemble. We show that in the fungus Neocallimastix sp. the basal bodies are discarded with the flagella when zoospores encyst. This shedding of basal bodies argues against centriolar persistence in any form and thus against their autonomy and endosymbiotic origin.

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23

Čačík, Marián. "Dudová and Duda before the Czech Constitutional Court: The question of autonomy of religious organizations." Studia z Prawa Wyznaniowego 25 (December 22, 2022): 67–90. http://dx.doi.org/10.31743/spw.13768.

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In the Czech Republic, the autonomy of churches is constitutionally guaranteed in a rather broad manner. The constitutional and legal basis for Church autonomy lies in the Charter of Fundamental Rights and Freedoms, which is part of the Czech constitutional order. It represents both an objective institutional guarantee (religious neutrality of the state) and the subjective right of religious communities to independence from the state and self-governance of their own affairs (the right to self-determination). Compared to other domains of the said autonomy, the staffing of churches is a relatively frequent subject of theoretical reflection and decision-making on the part of Czech courts. The Constitutional Court of the Czech Republic had to express its opinion on some problematic cases, in particular, the limits of Church autonomy. The case of Duda and Dudová is an example of a conflict between civil rights and the autonomy of churches in the modern Czech history. It started with Duda and Dudová’s dismissal from the pastoral ministry in the Czechoslovak Hussite Church in 1993, and the last (so far) decision related to this case was issued by the Constitutional Court in 2021. This article discusses the long and tortuous journey through the Czech judiciary system, which Duda, Dudová, and the Czechoslovak Hussite Church had to go through in order to clarify consequences of church autonomy. A particular deviation in the Supreme Court’s decision-making played an interesting role in this process. However, it was the Constitutional Court, which acted as the guardian of constitutional values (including the internal autonomy of churches), that placed this anomaly in the decision-making of the Supreme Court and, subsequently, general courts back within constitutional limits.

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24

Gilkerson, Robert W., Eric A. Schon, Evelyn Hernandez, and Mercy M. Davidson. "Mitochondrial nucleoids maintain genetic autonomy but allow for functional complementation." Journal of Cell Biology 181, no. 7 (June 23, 2008): 1117–28. http://dx.doi.org/10.1083/jcb.200712101.

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Mitochondrial DNA (mtDNA) is packaged into DNA-protein assemblies called nucleoids, but the mode of mtDNA propagation via the nucleoid remains controversial. Two mechanisms have been proposed: nucleoids may consistently maintain their mtDNA content faithfully, or nucleoids may exchange mtDNAs dynamically. To test these models directly, two cell lines were fused, each homoplasmic for a partially deleted mtDNA in which the deletions were nonoverlapping and each deficient in mitochondrial protein synthesis, thus allowing the first unequivocal visualization of two mtDNAs at the nucleoid level. The two mtDNAs transcomplemented to restore mitochondrial protein synthesis but were consistently maintained in discrete nucleoids that did not intermix stably. These results indicate that mitochondrial nucleoids tightly regulate their genetic content rather than freely exchanging mtDNAs. This genetic autonomy provides a molecular mechanism to explain patterns of mitochondrial genetic inheritance, in addition to facilitating therapeutic methods to eliminate deleterious mtDNA mutations.

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25

Ballesteros-Arias, Luna, Joana G. Silva, Rafael A. Paiva, Belén Carbonetto, Pedro Faísca, and Vera C. Martins. "T Cell Acute Lymphoblastic Leukemia as a Consequence of Thymus Autonomy." Journal of Immunology 202, no. 4 (January 16, 2019): 1137–44. http://dx.doi.org/10.4049/jimmunol.1801373.

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26

Hart, K., and M. Bienz. "A test for cell autonomy, based on di-cistronic messenger translation." Development 122, no. 3 (March 1, 1996): 747–51. http://dx.doi.org/10.1242/dev.122.3.747.

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We have devised a test for cell autonomy of a gene that is switched on ectopically in a clone of cells, allowing us to ask whether the wild-type activity of this gene can influence neighbouring cells. To switch on the test gene, we used the yeast FRT system, and marked the FRT-generated cell clone by co-expressing beta-galactosidase. Co-expression is achieved by a stretch of 5′ untranslated mRNA from the homeotic gene Ultrabithorax (Ubx), which is inserted between the two coding sequences. We show that this Ubx sequence mediates efficient and reliable di-cistronic mRNA translation in wing imaginal discs of Drosophila. Applying our test to Ubx, we find that ectopic Ubx in wing discs strictly coincides with beta-galactosidase expression. Consequently, wing cells are transformed into cells that appear to be intermediates between wing and haltere cells, contesting the view that homeotic genes act as binary switches.

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27

Bershad, Anya K., Miguel A. Fuentes, and David C. Krakauer. "Developmental autonomy and somatic niche construction promotes robust cell fate decisions." Journal of Theoretical Biology 254, no. 2 (September 2008): 408–16. http://dx.doi.org/10.1016/j.jtbi.2008.05.018.

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28

Sorensen, S. H., and D. Adornetto-Garcia. "Staff Autonomy and Decision Making in Large Stem Cell Transplant Clinic." Biology of Blood and Marrow Transplantation 17, no. 2 (February 2011): S358. http://dx.doi.org/10.1016/j.bbmt.2010.12.609.

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29

Friederici, Angela D. "Autonomy of syntactic processing and the role of Broca's area." Behavioral and Brain Sciences 19, no. 4 (December 1996): 634–35. http://dx.doi.org/10.1017/s0140525x0004334x.

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AbstractBoth autonomy and local specificity are compatible with observed interconnectivity at the cell level when considering two different levels: cell assemblies and brain systems. Early syntactic structuring processes in particular are likely to representan autonomous module in the language/brain system.

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30

Lee, Hongkee. "Legal Protection of Local Creators for Cultural Autonomy." Korean Society of Culture and Convergence 44, no. 7 (July 31, 2022): 443–57. http://dx.doi.org/10.33645/cnc.2022.7.44.7.443.

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This paper examines the protections and limitations of the current law on local creators from the perspective of cultural autonomy. The Constitution guarantees the basic cultural rights and the Framework Act on Culture(FAC) and other regulations makes them concrete. However, there is a lack of legal mechanisms to recognize the importance of local creators and protect them. Many countries strive to enhance regional creativity and protect local creators by emphasizing autonomous creativity by introducing legal systems that are appropriate to their cultural environment and circumstances. This paper examines the laws related in the US, UK, and Japan, and draws implications for legislative improvement. In conclusion, the value of creation is more emphasized in the FAC, etc., and norms should be improved through local government ordinances that can reflect the characteristics of local creativity.

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31

Fizzotti, Gabriella, Sandro Re, and Giulio Varrone. "Rehabilitation of Paraplegia Secondary to Giant cell Tumor of Bone Case Report." Journal of Orthopaedic Case Reports 12, no. 9 (2022): 15–19. http://dx.doi.org/10.13107/jocr.2022.v12.i09.2996.

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Introduction: Neoplastic patients with spinal cord injury (SCI) who commonly present at rehabilitation units exhibit different characteristics from traumatic SCI patients but the rehabilitation results are similar. The aim of this paper is to describe the rehabilitation outcome in a patient with paraplegia caused by giant cell tumor of bone (GCTB) located at D11 level of spine. Case Report: The patient was a 26-year-old Chinese man who had a history of back pain complicated by paraplegia. Magnetic resonance imaging (NMR) evidenced giant cell tumor removed surgically. Individual rehabilitation program aimed to recovery walking autonomy was proposed to the patient. Conclusion: A case report recovered a good grade of autonomy in walking function and returned to daily activities.

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32

Larsen, William J., Lin Chen, Robert Powers, Hong Zhang, Paul T. Russell, Carolyn Chambers, Karla Hess, and Robert Flick. "Cumulus expansion initiates physical and developmental autonomy of the oocyte." Zygote 4, no. 04 (November 1996): 335–41. http://dx.doi.org/10.1017/s096719940000335x.

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As meiosis is initiated and the oogonium is transformed into a primary oocyte, the female germ cell becomes intimately invested by a single squamous layer of sex cord epithelium. As the follicle cell population expands during the initial stages of the ovarian cycle, oocyte and follicle cells become increasingly connected to one another by one of the most extensive populations of gap junctions documented in any epithelium (reviewed in Larsen & Wert, 1988).

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33

J.D., R. Alta Charo. "Children by choice: reproductive technologies and the boundaries of personal autonomy." Nature Cell Biology 4 (October 2002): S23—S29. http://dx.doi.org/10.1038/ncb-nm-fertilitys23.

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34

Furner, I. J., J. F. Ainscough, J. A. Pumfrey, and L. M. Petty. "Clonal analysis of the late flowering fca mutant of Arabidopsis thaliana: cell fate and cell autonomy." Development 122, no. 3 (March 1, 1996): 1041–50. http://dx.doi.org/10.1242/dev.122.3.1041.

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Plants that are homozygous for the fca mutation bolt and flower later than wild-type (FCA) plants. The mutation has little or no effect on the fate map of the dry seed, except that the central cells give rise to further rosette leaves instead of the bolting stem, cauling leaves and inflorescence. The large and variable sectors affecting the late rosette leaves of fca plants were used to generate an abstract frequency-distance fate map of vegetative growth. The map relates the initiation of leaves in the plant apex to their final arrangements. The map was found to be a shallow dome with phyllotaxy superimposed on its surface. X-irradiation was used to provoke loss of the FCA allele from cells in heterozygous seeds. The resulting fca sectors had no effect on the plant phenotype. Even when L2 and L3 cells at the centre of the meristem could not produce the FCA gene product, bolting and flowering was unaffected. The genotypically fca mutant tissue was incorporated into phenotypically normal stems, cauline leaves and flowers. Possible reasons for the non-autonomous behaviour of the trait are discussed.

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35

Furner, Ian, Louise Ellis, Saleha Bakht, Bushra Mirza, and Mazhar Sheikh. "CAUT lines: a novel resource for studies of cell autonomy in Arabidopsis." Plant Journal 53, no. 4 (September 19, 2007): 645–60. http://dx.doi.org/10.1111/j.1365-313x.2007.03321.x.

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36

Noguchi, Takako, Tanya L. Leise, Nathaniel J. Kingsbury, Tanja Diemer, Lexie L. Wang, Michael A. Henson, and David K. Welsh. "Calcium Circadian Rhythmicity in the Suprachiasmatic Nucleus: Cell Autonomy and Network Modulation." eneuro 4, no. 4 (July 2017): ENEURO.0160–17.2017. http://dx.doi.org/10.1523/eneuro.0160-17.2017.

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37

Bemis, Shannon M., and Keiko U. Torii. "Autonomy of cell proliferation and developmental programs during Arabidopsis aboveground organ morphogenesis." Developmental Biology 304, no. 1 (April 2007): 367–81. http://dx.doi.org/10.1016/j.ydbio.2006.12.049.

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38

Oates, Andrew C. "Waiting on the Fringe: cell autonomy and signaling delays in segmentation clocks." Current Opinion in Genetics & Development 63 (August 2020): 61–70. http://dx.doi.org/10.1016/j.gde.2020.04.008.

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39

Centanin, Lázaro, Andrés Dekanty, Nuria Romero, Maximiliano Irisarri, Thomas A. Gorr, and Pablo Wappner. "Cell Autonomy of HIF Effects in Drosophila: Tracheal Cells Sense Hypoxia and Induce Terminal Branch Sprouting." Developmental Cell 14, no. 4 (April 2008): 547–58. http://dx.doi.org/10.1016/j.devcel.2008.01.020.

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40

Salazar, Santiago, Dionisio Malagón, Edwin Forero-García, María Josefina Torres, and Marco Antonio Velasco Peña. "Evaluation of a Hydrogen Powered Scooter Toy Prototype." Machines 10, no. 12 (November 29, 2022): 1134. http://dx.doi.org/10.3390/machines10121134.

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Анотація:

Electric scooters are used as alternative ways of transport because they easily make travel faster. However, the batteries can take around 5 h to charge and have an autonomy of 30 km. With the presence of the hydrogen cell, a hybrid system reduces the charging times and increases the autonomy of the vehicle by using two types of fuel. An increase of up to 80% in maximum distance and of 34% in operating times is obtained with a 1:10 scale prototype with the hydrogen cell; although more energy is withdrawn, the combined fuel efficiency increases, too. This suggests the cell that is used has the same behavior as some official reported vehicles, which have a long range but low power. This allows concluding that use of the cell is functional for load tests and that the comparison factor obtained works as input for real-scale scooter prototypes to compete with the traditional electric scooters.

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41

Listevnik, Maria, H. Rösier, E. P. Ritter, and Claudine Als. "Separation of Autonomous Function from Cell Density in Non-Immunogenic Hyperthyroidism." Nuklearmedizin 34, no. 06 (1995): 215–22. http://dx.doi.org/10.1055/s-0038-1629717.

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SummaryA new quantitative subtraction method of thyroid scans is proposed which shows that regional function (F) by far exceeds regional cellularity or cell density (C) in potentially toxic thyroidal areas of non-immunogenic hyperthyroidism (NIH). Methods: A multistep processing of radioiodine and MIBI thyroid scans of patients with non-immunogenic hyperthyroidism led to normalized images of regional function excess and of perinodular enhancement. Two numeric factors were derived from regions of interest: Q (cell density ratio) comparing MIBI uptake in autonomous and suppressed areas and T (toxicity index): the maximal F/C contrast. Results: Q never exceeded 61; T, however, expanded toxicity levels over a range of 6-8735 with toxic adenomas (median = 165) and with hot areas of multifocal functional autonomy (median = 15). T was weakly correlated to serum TT3 (r = 0.41), but not to autonomous tissue mass, ultrasonographic or cytologic criteria. Conclusions: T is governed by inherent features of autonomous tissue and the response of the imbedded thyroid tissue to TSH stimulation. This standardized technique consolidates experiences from visual analysis; the huge T range mirrors the natural evolution from compensated autonomy towards hyperthyroid, decompensated stages.

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42

Meyer, Kathrin, and Brian K. Kaspar. "Glia–neuron interactions in neurological diseases: Testing non-cell autonomy in a dish." Brain Research 1656 (February 2017): 27–39. http://dx.doi.org/10.1016/j.brainres.2015.12.051.

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43

Van Roessel, Peter, Neil M. Hayward, Claudia S. Barros, and Andrea H. Brand. "Two-color GFP imaging demonstrates cell-autonomy of GAL4-driven RNA interference indrosophila." genesis 34, no. 1-2 (September 2002): 170–73. http://dx.doi.org/10.1002/gene.10146.

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Maire, Théo, and Hyun Youk. "Molecular-Level Tuning of Cellular Autonomy Controls the Collective Behaviors of Cell Populations." Cell Systems 1, no. 5 (November 2015): 349–60. http://dx.doi.org/10.1016/j.cels.2015.10.012.

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Müller, Ralph-Axel. "Innateness, autonomy, universality? Neurobiological approaches to language." Behavioral and Brain Sciences 19, no. 4 (December 1996): 611–31. http://dx.doi.org/10.1017/s0140525x00043296.

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Анотація:

AbstractThe concepts of the innateness, universality, species-specificity, and autonomy of the human language capacity have had an extreme impact on the psycholinguistic debate for over thirty years. These concepts are evaluated from several neurobiological perspectives, with an emphasis on the emergence of language and its decay due to brain lesion and progressive brain disease.Evidence of perceptuomotor homologies and preadaptations for human language in nonhuman primates suggests a gradual emergence of language during hominid evolution. Regarding ontogeny, the innate component of language capacity is likely to be polygenic and shared with other developmental domains. Dissociations between verbal and nonverbal development are probably rooted in the perceptuomotor specializations of neural substrates rather than the autonomy of a grammar module. Aphasiologicaldata often assumed to suggest modular linguistic subsystems can be accounted for in terms of a neurofunctional model incorporating perceptuomotor-based regional specializationsand distributivity of representations. Thus, dissociations between grammatical functors and content words are due to different conditions of acquisition and resulting differences in neural representation. Human brains are characterized by multifactorial interindividual variability, and strict universality of functional organization is biologically unrealistic.A theoretical alternative is proposed according to which (1) linguistic specialization of brain areas is due to epigenetic and probabilistic maturational events, not to genetic ”hard-wiring,” and (2) linguistic knowledge is neurally represented in distributed cell assemblies whose topography reflects the perceptuomotor modalities involved in the acquisition and use of a given item of knowledge.

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Dange, Thomas, David Grünwald, Antje Grünwald, Reiner Peters, and Ulrich Kubitscheck. "Autonomy and robustness of translocation through the nuclear pore complex: a single-molecule study." Journal of Cell Biology 183, no. 1 (September 29, 2008): 77–86. http://dx.doi.org/10.1083/jcb.200806173.

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All molecular traffic between nucleus and cytoplasm occurs via the nuclear pore complex (NPC) within the nuclear envelope. In this study we analyzed the interactions of the nuclear transport receptors kapα2, kapβ1, kapβ1ΔN44, and kapβ2, and the model transport substrate, BSA-NLS, with NPCs to determine binding sites and kinetics using single-molecule microscopy in living cells. Recombinant transport receptors and BSA-NLS were fluorescently labeled by AlexaFluor 488, and microinjected into the cytoplasm of living HeLa cells expressing POM121-GFP as a nuclear pore marker. After bleaching the dominant GFP fluorescence the interactions of the microinjected molecules could be studied using video microscopy with a time resolution of 5 ms, achieving a colocalization precision of 30 nm. These measurements allowed defining the interaction sites with the NPCs with an unprecedented precision, and the comparison of the interaction kinetics with previous in vitro measurements revealed new insights into the translocation mechanism.

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Rolader, R., J. Cheeley, L. Lawley, C. Haydeck, J. Mackelfresh, and S. C. Chen. "387 Teledermatology-based inpatient consult rotations engender autonomy for trainees." Journal of Investigative Dermatology 140, no. 7 (July 2020): S50. http://dx.doi.org/10.1016/j.jid.2020.03.395.

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Hino Samuel Jose. "FROM INDO-PACIFIC CENTRALITY TO STRATEGIC AUTONOMY: ASEAN – US PERSPECTIVE." Indonesian Journal of International Relations 6, no. 1 (February 28, 2022): 205–28. http://dx.doi.org/10.32787/ijir.v6i1.311.

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Indo-Pacific is indeed a versatile region with vast geoeconomic and geopolitical advantages and potentials, with ASEAN at its center. Strategic engagement of countries whether to bandwagon or balance major power’s rivalries are pretty much a pertinent deliberation for the last and next decades to come as the global shifting is now moving towards the Indo-Pacific region. This paper employs qualitative analysis to answer the main contentions of: (1) how minilateralism affects Indo-Pacific, and what ASEAN-US role can be explored; and (2) does ASEAN-US matter and how it could actively find convergences in navigating forward in the rules-based region. The author suggests that looking west and being concerned the east or the other way around can be a sufficient strategy in constructing ASEAN-US engagement amid the rising minilateral groupings and concerns against the “crippled” ASEAN centrality since AUKUS and the recent developments in the region.

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Coultrap, Steven J., Isabelle Buard, Jaqueline R. Kulbe, Mark L. Dell'Acqua, and K. Ulrich Bayer. "CaMKII Autonomy Is Substrate-dependent and Further Stimulated by Ca2+/Calmodulin." Journal of Biological Chemistry 285, no. 23 (March 30, 2010): 17930–37. http://dx.doi.org/10.1074/jbc.m109.069351.

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Winter, Nikola, Gregor Kollwig, Shoudong Zhang, and Friedrich Kragler. "MPB2C, a Microtubule-Associated Protein, Regulates Non-Cell-Autonomy of the Homeodomain Protein KNOTTED1." Plant Cell 19, no. 10 (October 2007): 3001–18. http://dx.doi.org/10.1105/tpc.107.044354.

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