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Статті в журналах з теми "CDKIs"
Campbell, Grace Jean, Emma Langdale Hands, and Mathew Van de Pette. "The Role of CDKs and CDKIs in Murine Development." International Journal of Molecular Sciences 21, no. 15 (July 28, 2020): 5343. http://dx.doi.org/10.3390/ijms21155343.
Повний текст джерелаGiannone, Gaia, Valentina Tuninetti, Eleonora Ghisoni, Sofia Genta, Giulia Scotto, Gloria Mittica, and Giorgio Valabrega. "Role of Cyclin-Dependent Kinase Inhibitors in Endometrial Cancer." International Journal of Molecular Sciences 20, no. 9 (May 12, 2019): 2353. http://dx.doi.org/10.3390/ijms20092353.
Повний текст джерелаPhuong, Lisa, Janki Patel, Nadia Baka, Jessica Goldman, Michael Lyudmer, Stephanie Shamir, Junwen Deng, Alvaro Alvarez Soto, and Jesus Del Santo Anampa Mesias. "Effect of cyclin-dependent kinase 4 and 6 inhibitors (CDKIs) on body composition (BC) in patients (pts) with hormone receptor-positive, HER2-negative (HR+/HER2-) metastatic breast cancer (MBC)." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e13033-e13033. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e13033.
Повний текст джерелаChao, Sheng-Hao, John R. Walker, Sumit K. Chanda, Nathanael S. Gray, and Jeremy S. Caldwell. "Identification of Homeodomain Proteins, PBX1 and PREP1, Involved in the Transcription of Murine Leukemia Virus." Molecular and Cellular Biology 23, no. 3 (February 1, 2003): 831–41. http://dx.doi.org/10.1128/mcb.23.3.831-841.2003.
Повний текст джерелаDao, Mo A., and Catherine M. Verfaillie. "STI571 Suppresses Proliferation by Restoring Nuclear Cyclin Dependent Kinase Inhibitors (CDKIs) while STI571+TRAIL Promotes Cell Death by Decreasing Cytoplasmic CDKIs." Blood 104, no. 11 (November 16, 2004): 1992. http://dx.doi.org/10.1182/blood.v104.11.1992.1992.
Повний текст джерелаAbdelmalak, Mary, Rajanbir Singh, Mohammed Anwer, Pavel Ivanchenko, Amritdeep Randhawa, Myra Ahmed, Anthony W. Ashton, Yanming Du, Xuanmao Jiao, and Richard Pestell. "The Renaissance of CDK Inhibitors in Breast Cancer Therapy: An Update on Clinical Trials and Therapy Resistance." Cancers 14, no. 21 (November 1, 2022): 5388. http://dx.doi.org/10.3390/cancers14215388.
Повний текст джерелаGervaso, Lorenzo, Alberto J. Montero, Xuefei Jia, and Alok A. Khorana. "Venous thromboembolism in breast cancer patients receiving cyclin-dependent kinase inhibitors." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): e18184-e18184. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e18184.
Повний текст джерелаZeki, K., I. Morimoto, T. Arao, S. Eto, and U. Yamashita. "Interleukin-1alpha regulates G1 cell cycle progression and arrest in thyroid carcinoma cell lines NIM1 and NPA." Journal of Endocrinology 160, no. 1 (January 1, 1999): 67–73. http://dx.doi.org/10.1677/joe.0.1600067.
Повний текст джерелаBuckley, S., B. Driscoll, K. D. Anderson, and D. Warburton. "Cell cycle in alveolar epithelial type II cells: integration of Matrigel and KGF." American Journal of Physiology-Lung Cellular and Molecular Physiology 273, no. 3 (September 1, 1997): L572—L580. http://dx.doi.org/10.1152/ajplung.1997.273.3.l572.
Повний текст джерелаBencivenga, Debora, Emanuela Stampone, Angela Vastante, Myassar Barahmeh, Fulvio Della Ragione, and Adriana Borriello. "An Unanticipated Modulation of Cyclin-Dependent Kinase Inhibitors: The Role of Long Non-Coding RNAs." Cells 11, no. 8 (April 14, 2022): 1346. http://dx.doi.org/10.3390/cells11081346.
Повний текст джерелаДисертації з теми "CDKIs"
Henderson, Andrew. "Isosteres of sulfonamide inhibitors of cyclin-dependent kinases (CDKs)." Thesis, University of Newcastle Upon Tyne, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512187.
Повний текст джерелаMarchetti, Francesco. "Structure-activity relationships for alkoxypirimidine inhibitors of cyclin-dependent kinases (CDK’s)." Thesis, University of Newcastle Upon Tyne, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556141.
Повний текст джерелаLolli, Graziano. "Cdks at the interface of cell cycle and and transcription regulation." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426389.
Повний текст джерелаChiurato, Matteo. "Synthèse de tétrahydropyrido-[isoindolones/isoquinolones/indolizinones] pour l'élaboration d'inhibiteurs de CDks." Orléans, 2007. http://www.theses.fr/2007ORLE2069.
Повний текст джерелаDelmas, Christelle. "Modes de régulation de l'inhibiteur de CDKs, p27kip1, par les MAPKsp42/p44." Toulouse 3, 2003. http://www.theses.fr/2003TOU30006.
Повний текст джерелаBettayeb, Karima. "Optimisation et caractérisation de nouveaux inhibiteurs pharmacologiques de kinases cycline-dépendantes (CDKs)." Rennes 1, 2008. http://www.theses.fr/2008REN1S025.
Повний текст джерелаCyclin-dependent kinases (CDKs) are key regulators of cell division cycle (CDK1, 2, 3, 4, 6, 7), apoptosis (CDK1, 5), and transcription (CDK7, 9). Pharmacological inhibitors of CDKs constitute a new family of potential antitumor agents: ten are under clinical trials, among which roscovitine, was discovered in our laboratory. My thesis is about identification, optimisation and characterization of biochemical and cellular effects of three new kinase inhibitory classes: 7-bromo-indirubins (7BIO), meriolin and new analogs of roscovitine (N&N1 and C&R8). 7BIO induces non-apoptotic cell death through an unknown mechanism (no release of cytochrome C, nor caspase activation). On the other hand, meriolins and second generation roscovitine analogs induce a classical apoptosis due to CDK9 inhibition, thus leading to disappearance of the cell survival factor, Mcl-1. These three classes of chemicals display promising anti-proliferative and antitumor properties
Wołowiec, Dariusz. "Étude des CDKS et des cyclines dans le tissu lymphoïde normal et pathologique." Lyon 1, 1995. http://www.theses.fr/1995LYO1T147.
Повний текст джерелаAppleyard, Lindsey Jemma. "Overcoming financial exclusion : Community Development Finance Institutions (CDFIs) and the balancing of financial and social objectives." Thesis, University of Birmingham, 2008. http://etheses.bham.ac.uk//id/eprint/386/.
Повний текст джерелаBaïdi, Feriel. "Simplicity and complexity in cell cycle control." Thesis, Rennes 1, 2016. http://www.theses.fr/2016REN1B021.
Повний текст джерелаThe cyclin-dependent protein kinases (CDKs) are at the core of cell cycle control. In fission yeast, cell proliferation is regulated by CDK1/Cdc2 in association with the four cyclins Cdc13, Cig1, Cig2 and Puc1 at different stages of the cell cycle. However, this complex endogenous system can be replaced by a minimal module consisting of a fusion between Cdc2 and Cdc13 in the absence of G1/S cyclins. Surprisingly, this minimal CDK network drives the entire cell cycle in a wild type manner. Since a number of aspects of cell cycle control in fission yeast appear to be dispensable, we asked why similarly simplified circuits were not selected over the complex endogenous network during evolution. This led us to investigate the limits of such minimal systems, in particular when challenged by different stresses. Unexpectedly, we uncovered that simplification of the CDK network confers resistance to replication stress. We showed that this phenotype is independent from the CDK inhibitor Rum1 and the existing checkpoint pathways. It solely relies on operating the entire cell cycle with a single cyclin, Cdc13, and is associated with reduced genome instability when replication is challenged. However, it is not the consequence of changes in replication organisation along the chromosomes. Our data suggest that G1/S cyclin-associated Cdc2 activity may represent an alternative as yet unknown means of modulating cellular response to DNA stress. We also took advantage of a derivative of the minimal cell cycle network, in which Cdc2 is made sensitive to specific chemical inhibition. As a result, CDK activity can be externally modulated and cell cycle phases can be precisely controlled. Using this system, we re-visited the interplay between CDK and periodic transcription, a highly conserved process that is critical for proper cell proliferation. In contrast with previous studies in budding yeast, we demonstrate that periodic transcription in fission yeast is not independent from cell cycle progression. On the contrary, our work reveals that cell cycle transcriptional oscillations rely on quantitative changes in CDK activity levels. We therefore propose a new model, in which cell cycle progression and periodic transcription are intimately coupled through their common dependency on a unique input, namely CDK activity levels
Tikad, Abdellatif. "Développement de nouvelles pyrido[3,2-d]pyrimidines polyfonctionnalisées : application à la synthèse d’inhibiteurs de CDKs." Orléans, 2008. http://www.theses.fr/2008ORLE2079.
Повний текст джерелаКниги з теми "CDKIs"
Lehr, Margaret B. Best practices for CDFIs: Key principles for performance. Philadelphia, PA (924 Cherry St., Second Fl, Philadelphia 19107): National Community Capital, 1998.
Знайти повний текст джерелаTreasury, Great Britain, ed. Mapping of credit unions and community development finance institutions (CDFIs). London: HMSO, 2005.
Знайти повний текст джерелаChapman, Deborah Lynne. Identification of murine B-type cyclins expressed during gametogenesis and examination of their potential functions in association with CDC2 and CDKS. [New York]: [Columbia University], 1993.
Знайти повний текст джерелаImmergluck, Daniel. CRA & CDFIs: The Community Reinvestment Act and community development financial institutions : qualified investments, community development lending, and lessons from the new CRA performance evaluations. Chicago (407 S. Dearborn, Chicago 60605): Woodstock Institute, 1998.
Знайти повний текст джерелаCommunity development financial institutions (CDFIs): Their unique role and challenges serving lower-income, underserved, and minority communities : hearing before the Committee on Financial Services, U.S. House of Representatives, One Hundred Eleventh Congress, second session, March 9, 2010. Washington: U.S. G.P.O., 2010.
Знайти повний текст джерелаUnited States. National Aeronautics and Space Administration, ed. Crustal Dynamics Data Information System: CDDIS. [Washington, DC: National Aeronautics and Space Administration, 1993.
Знайти повний текст джерелаTansey, Charles, Michael Swack, and Michael Tansey. Capital Markets, Cdfis, and Organizational Credit Risk. Lulu Press, Inc., 2010.
Знайти повний текст джерелаMacarthur Communicative Development Inventories (Cdis): Words And Sentences. Brookes Publishing Company, 2003.
Знайти повний текст джерелаStaff, International Monetary Fund. Coordinated Direct Investment Survey Guide 2015 (CDIS 2015). International Monetary Fund, 2015.
Знайти повний текст джерелаMacarthur Communicative Development Inventories (Cdis): Words And Gestures. Brookes Publishing Company, 2003.
Знайти повний текст джерелаЧастини книг з теми "CDKIs"
Solomon, M. J., and P. Kaldis. "Regulation of CDKs by phosphorylation." In Results and Problems in Cell Differentiation, 79–109. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-540-69686-5_4.
Повний текст джерелаMir, Manzoor Ahmad, and Abrar Yousuf Mir. "Breast Tumor Microenvironment and CDKs." In Therapeutic potential of Cell Cycle Kinases in Breast Cancer, 149–74. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-8911-7_7.
Повний текст джерелаGupta, Anand, Anita Kumari, Boris Kundu, and Isha Agarwal. "CDIS: Circle Density Based Iris Segmentation." In Communications in Computer and Information Science, 295–306. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03547-0_28.
Повний текст джерелаMir, Manzoor Ahmad, and Burhan Ul Haq. "Therapeutic Implications of CDKs in Breast Cancer." In Therapeutic potential of Cell Cycle Kinases in Breast Cancer, 233–52. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-8911-7_11.
Повний текст джерелаMir, Manzoor Ahmad, and Umar Y. Mir. "Targeting CDKs with Other Chemotherapeutic Drugs: A Combinatorial Approach." In Therapeutic potential of Cell Cycle Kinases in Breast Cancer, 269–89. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-8911-7_13.
Повний текст джерелаNoll, Carey E. "Data archiving and distribution for the Crustal Dynamics Project: The CDDIS." In Contributions of Space Geodesy to Geodynamics: Technology, 27–45. Washington, D. C.: American Geophysical Union, 1993. http://dx.doi.org/10.1029/gd025p0027.
Повний текст джерелаPinhero, Reena, and Krassimir Yankulov. "Expression and Purification of Recombinant CDKs: CDK7, CDK8, and CDK9." In Methods in Molecular Biology, 13–28. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-2926-9_3.
Повний текст джерелаWilliams, Paul D., Kevin P. Anchor, John L. Bebo, Gregg H. Gunsch, and Gary D. Lamont. "CDIS: Towards a Computer Immune System for Detecting Network Intrusions." In Lecture Notes in Computer Science, 117–33. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/3-540-45474-8_8.
Повний текст джерелаMcClendon, A. Kathleen, Jeffry L. Dean, and Erik S. Knudsen. "Regulation of Pre-RC Assembly: A Complex Symphony Orchestrated by CDKs." In Cell Cycle Deregulation in Cancer, 43–55. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-1770-6_3.
Повний текст джерелаGallastegui, Edurne, and Oriol Bachs. "Expression and Purification of Recombinant Cyclins and CDKs for Activity Evaluation." In Methods in Molecular Biology, 9–12. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-2926-9_2.
Повний текст джерелаТези доповідей конференцій з теми "CDKIs"
Chen, Da-Ming, Y. F. Xu, and W. D. Zhu. "Non-Model-Based Multiple Damage Identification of Beams Under Spatially Dense Vibration Measurement." In ASME 2017 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/imece2017-72430.
Повний текст джерелаSaxena, Bhawanjali, Kumud Pant, Bhasker Pant, and K. R. Pardasani. "Dipeptide based SVM model for prediction of CDKs and cyclins." In 2nd International Conference on Computer and Automation Engineering (ICCAE 2010). IEEE, 2010. http://dx.doi.org/10.1109/iccae.2010.5451233.
Повний текст джерелаSaxena, Bhawanjali, Kumud Pant, Bhasker Pant, and Neeru Adlakha. "Hybrid based SVM model for prediction of CDKs and cyclins." In 2nd International Conference on Computer and Automation Engineering (ICCAE 2010). IEEE, 2010. http://dx.doi.org/10.1109/iccae.2010.5451262.
Повний текст джерелаZhao, Tianna, Riccardo Serra, Michelle Guo, Peter C. Burger, Lisa M. Rooper, Betty Tyler, Christine L. Hann, and Gary L. Gallia. "CDKS Blockade Enhances In Vivo Efficacy of EGFR Inhibition in Chordomas." In Special Virtual Symposium of the North American Skull Base Society. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1725264.
Повний текст джерелаStevens, K. J., K. Lichti, I. A. Minchington, N. Janke-Gilman, T. Mactutis, D. Rook, and P. Bondurant. "Conductor Damage Inspection System for overhead ACSR power cables CDIS on ACSR." In 2013 Seventh International Conference on Sensing Technology (ICST). IEEE, 2013. http://dx.doi.org/10.1109/icsenst.2013.6727780.
Повний текст джерелаRajput, Sandeep, Zhanfang Guo, and Cynthia Ma. "Abstract 3097: CDKs inhibitor: potential monotherapy for treatment of triple-negative breast cancer." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-3097.
Повний текст джерелаLu, Shuyan, Wenyue Hu, Tae Sung, Brad Hirakawa, Marina Amaro, and Bart Jessen. "Abstract 99: Phenotypic characterization of knockdown of CDKs in the intestinal epithelial cells." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-99.
Повний текст джерелаTadesse, Solomon, Laychiluh Bantie, Khamis Tomusange, Saiful Islam, Muhammed H. Rahaman, Benjamin Noll, Frankie Lam, Mingfeng Yu, and Shudong Wang. "Abstract 2353: CDKI-15, a novel and highly selective CDK4/6 inhibitor: discovery,in vitroandin vivoanticancer efficacy." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2353.
Повний текст джерелаRieß, C., CF Classen, and C. Maletzki. "CDKs as target structures for cancer therapy – an in vitro analysis on patient-derived glioblastoma cell lines." In 28th Annual Meeting of the working group “Experimental Neuro-Oncology”. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1696331.
Повний текст джерелаShapiro, G. "Abstract MS1-1: Beyond CDK 4/6: Targeting additional cell cycle and transcriptional CDKs in breast cancer." In Abstracts: Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium; December 8-12, 2015; San Antonio, TX. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.sabcs15-ms1-1.
Повний текст джерелаЗвіти організацій з теми "CDKIs"
Tansey, Charles, Michael Swack, Michael Tansey, and Vicky Stein. Capital markets, CDFIs, and organizational credit risk. University of New Hampshire Libraries, 2010. http://dx.doi.org/10.34051/p/2020.123.
Повний текст джерелаJayson Wharton, Edward Seabury, Gus Caffrey, and Phili. Summary Report: INL CDCIS Cask Scanner Testing at. Office of Scientific and Technical Information (OSTI), April 2013. http://dx.doi.org/10.2172/1087695.
Повний текст джерелаSwack, Michael, Eric Hangen, and Jack Northrup. CDFIs Stepping into the Breach: An Impact Evaluation—Summary Report. University of New Hampshire Libraries, 2015. http://dx.doi.org/10.34051/p/2020.228.
Повний текст джерелаNorthrup, Jack, Eric Hangen, and Michael Swack. CDFIs and Online Business Lending: A Review of Recent Progress, Challenges, and Opportunities. University of New Hampshire Libraries, 2016. http://dx.doi.org/10.34051/p/2020.276.
Повний текст джерелаWilliams, Teshanee, Jamie McCall, Natalie Prochaska, and Tamra Thetford. How Community Development Financial Institutions (CDFIs) are shaped by Funders through Data Collection, Impact Measurement, and Evaluation. Carolina Small Business Development Fund, November 2022. http://dx.doi.org/10.46712/cdfi.evaluation.pressures.
Повний текст джерелаTansey, Charles, and Michael Swack. The Potential Role For CDFIs in the Opportunity Zones of the Investing in Opportunities Act (IIOA). University of New Hampshire Libraries, 2019. http://dx.doi.org/10.34051/p/2020.350.
Повний текст джерелаMcCall, Jamie, and Emily Stallings. Assessing Public, Private, and Philanthropic Support for CDFIs: Data on Contributing Operating Revenues and Measures of Efficiency. Carolina Small Business Development Fund, December 2020. http://dx.doi.org/10.46712/cdfi.revenue.sources.
Повний текст джерелаHangen, Eric, and Michael E. Hangen. CDFIs Can Make the SBA PPP Loan Program Work for Smaller, Minority-Owned, and Women-Owned, Small Businesses. University of New Hampshire Libraries, 2020. http://dx.doi.org/10.34051/p/2020.386.
Повний текст джерелаMcCall, Jamie, Nora Anzawi, Miles Zeller, and James Onorevole. Growth, Equity, and Individual Welfare: A Theoretical Framework for “Moving the Needle” on CDFI Impact Evaluation. Carolina Small Business Development Fund and AltCap, January 2023. http://dx.doi.org/10.46712/evaluation.frameworks.
Повний текст джерела