Дисертації з теми "Carrier and Transport Proteins"
Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями
Ознайомтеся з топ-50 дисертацій для дослідження на тему "Carrier and Transport Proteins".
Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.
Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.
Переглядайте дисертації для різних дисциплін та оформлюйте правильно вашу бібліографію.
Covey, Scott D. Trigatti Bernardo L. "Carrier mediated lipid transport /." *McMaster only, 2003.
Знайти повний текст джерелаKwan, Miu-fan, and 關妙芬. "Characterization of TM4 of NRAMP1: implication for FEII transport." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B29275143.
Повний текст джерелаGrabski, Robert. "Using RNA interference to study the function of the tethering protein p115 in ER-Golgi traffic." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2008p/grabski.pdf.
Повний текст джерелаParry, Geraint. "Investigating the mechanisms of auxin transport." Thesis, University of Nottingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391391.
Повний текст джерелаChristoffersen, Catherine Anne. "Molecular analysis of the ferric-enterobactin fepDGC transport permease complex in escherichia coli." free to MU campus, to others for purchase, 1997. http://wwwlib.umi.com/cr/mo/fullcit?p9842593.
Повний текст джерелаBright, Alison R. "A Role for Intraflagellar Transport Proteins in Mitosis: A Dissertation." eScholarship@UMMS, 2013. https://escholarship.umassmed.edu/gsbs_diss/682.
Повний текст джерелаBright, Alison R. "A Role for Intraflagellar Transport Proteins in Mitosis: A Dissertation." eScholarship@UMMS, 2006. http://escholarship.umassmed.edu/gsbs_diss/682.
Повний текст джерелаNelson, Bryn D. "Examining the role of MalG in the assembly and function of the maltose transport complex in Escherichia coli : implications for the study of integral membrane proteins /." Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/11508.
Повний текст джерелаBradley, Shannon. "Polymorphisms in the promoter region of the dopamine transporter : a candidate locus for alcohol abuse." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0029/MQ64326.pdf.
Повний текст джерелаMillman, Jonathan Scott Andrews David. "Characterization of membrane-binding by FtsY, the prokaryote SRP receptor /." *McMaster only, 2002.
Знайти повний текст джерелаAhlin, Gustav. "In vitro and in silico prediction of drug-drug interactions with transport proteins." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-107492.
Повний текст джерелаKennedy, Kathleen Anne. "Assembly of the maltose transport complex of Escherichia coli and the dimerization, localization, and functional domain structure of its ATP-binding subunit, MalK /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/11504.
Повний текст джерелаYang, Ying. "Mechanism of metal delivery and binding to transport sites of Cu+-transporting ATPases." Link to electronic thesis, 2005. http://www.wpi.edu/Pubs/ETD/Available/etd-042905-112044/.
Повний текст джерелаHansson, Stefan R. "The serotonin transporter and vesicular monoamine transporters during development." Lund : Lund University, 1998. http://catalog.hathitrust.org/api/volumes/oclc/68945023.html.
Повний текст джерелаThomas, Dustin G. "Zinc transport protein-1 (ZnT1) contributes to Zn2⁺ efflux in primary cultures of rat cortical neurons." Ohio : Ohio University, 2006. http://www.ohiolink.edu/etd/view.cgi?ohiou1163544193.
Повний текст джерелаMahato, Deependra. "Mutation of Polaris, an Intraflagellar Transport Protein, Shortens Neuronal Cilia." Thesis, University of North Texas, 2005. https://digital.library.unt.edu/ark:/67531/metadc4856/.
Повний текст джерелаGabriel, Luke R. "Dynamic Regulation at the Neuronal Plasma Membrane: Novel Endocytic Mechanisms Control Anesthetic-Activated Potassium Channels and Amphetamine-Sensitive Dopamine Transporters: A Dissertation." eScholarship@UMMS, 2013. http://escholarship.umassmed.edu/gsbs_diss/725.
Повний текст джерелаLin, Xiaohui, and 林晓晖. "Molecular analysis of an iron transporter gene of Burkholderia speciesMBA4." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B4218194X.
Повний текст джерелаBravo, Silvina Alejandra. "The di/tri-peptide transporters PEPT1 and PEPT2 : expression and regulation in the intestinal Caco-2 and renal SKPT0193 cl.2 cell lines /." Cph. : Department of Pharmaceutics, The Danish University of Pharmaceutical Sciences, 2004. http://www.dfh.dk/phd/defences/silvinabravo.htm.
Повний текст джерелаBrault, Jeffrey J. "Creatine uptake and creatine transporter expression among rat skeletal muscle fiber types." free to MU Campus, others may purchase, 2003. http://wwwlib.umi.com/cr/mo/fullcit?p3091902.
Повний текст джерелаMadsen, Jacob. "Development of new PET and SPECT ligands for visualization of serotonin transporter in the brain /." Cph. : PET & Cyclotron Unit, Rigshospitalet, Copenhagen University Hospital : The Danish University Hospital, 2003. http://www.dfh.dk/phd/defences/jacobmadsen.htm.
Повний текст джерелаWoźnicka-Misăilă, Aleksandra. "An investigation and characterization of different ADP/ATP Carrier homologs." Thesis, Université Grenoble Alpes (ComUE), 2016. http://www.theses.fr/2016GREAV011/document.
Повний текст джерелаThe main objective of this PhD project was to gain new structural data on the mitochondrial ADP/ATP carriers and develop tools for micro- and nano-crystallography approaches applied to membrane protein structural biology.The main role of the ADP/ATP carrier (AAC) is to import and export ADP3- and ATP4- respectively between the intermembrane space and the matrix through the inner mitochondrial membrane. AAC is the best characterized among all mitochondrial carriers. Much has been done to investigate its function and structure. However, since structural data are only available for one conformation of the protein some fundamental questions about the different conformational states adopted during the transport process still need to be answered.In this thesis we considered 4 human AAC homologs as a main target. They are involved in different genetic diseases but play also a role in cancerogenesis. This thesis describes and compares in detail the functional and structural characterization of the human AAC isoforms. It was an essential step to give insight into their native properties and is a precious starting point for the drug development field.Since the structural biology field is rapidly developing especially in serial crystallography techniques, there are more and more new applications for samples preparation, mounting and measurements in order to improve the quality of the data collected at the synchrotrons. Hence, our second objective was to use different membrane protein samples to develop new crystal-friendly crystallization set up combined with different sample environment on the beamline toward faster, more efficient and simpler data collection
Blodgett, David M. "Human Erythrocyte Glucose Transporter (GLUT1) Structure, Function, and Regulation: A Dissertation." eScholarship@UMMS, 2007. https://escholarship.umassmed.edu/gsbs_diss/326.
Повний текст джерелаFollit, John A. "Building the Cell's Antenna: Protein Targeting to the Ciliary Membrane: A Dissertation." eScholarship@UMMS, 2012. https://escholarship.umassmed.edu/gsbs_diss/594.
Повний текст джерелаLin, Xiaohui. "Molecular analysis of an iron transporter gene of Burkholderia species MBA4." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B4218194X.
Повний текст джерелаReynolds, Annie 1978. "Over-expression of the potassium-chloride co-transporter KCC2 in developing zebrafish." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=98778.
Повний текст джерелаStange, Christoph. "Combining artificial Membrane Systems and Cell Biology Studies: New Insights on Membrane Coats and post-Golgi Carrier Formation." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-102218.
Повний текст джерелаBrohée, Sylvain. "Etude bioinformatique du réseau d'interactions entre protéines de transport ches les Fungi." Doctoral thesis, Universite Libre de Bruxelles, 2008. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210432.
Повний текст джерелаL'objectif global de notre travail consiste à combler ces lacunes et à préciser les interactions entre protéines membranaires chez la levure Saccharomyces cerevisiae et plus précisément, entre les transporteurs. Nous avons commencé notre travail par l'étude d'un jeu de données d'interactions à grande échelle entre toutes les perméases détectées par une méthode de double hybride spécialement adaptée aux protéines insolubles (split ubiquitin). Premièrement, la qualité des données a été estimée en étudiant le comportement global des données et des témoins négatifs et positifs. Les données ont ensuite été standardisées et filtrées de façon à ne conserver que les plus significatives. Ces interactions ont ensuite été étudiées en les modélisant dans un réseau d'interactions que nous avons étudié par des techniques issues de la théorie des graphes. Après une évaluation systématique de différentes méthodes de clustering, nous avons notamment recherché au sein du réseau des groupes de protéines densément interconnectées et de fonctions similaires qui correspondraient éventuellement à des complexes protéiques. Les résultats révélés par l'étude du réseau expérimental se sont révélés assez décevants. En effet, même si nous avons pu retrouver certaines interactions déjà décrites, un bon nombre des interactions filtrées semblait n'avoir aucune réalité biologique et nous n'avons pu retrouver que très peu de modules de protéines de fonction semblable hautement inter-connectées. Parmi ceux-ci, il est apparu que les transporteurs d'acides aminés semblaient interagir entre eux.
L'approche expérimentale n'ayant eu que peu de succès, nous l'avons contournée en utilisant des méthodes de génomique comparative d'inférence d'interactions fonctionnelles. Dans un premier temps, malgré une évaluation rigoureuse, l'étude des profils phylogénétiques (la prédiction d'interactions fonctionnelles en étudiant la corrééélation des profils de présence - absence des gènes dans un ensemble de génomes), n'a produit que des résultats mitigés car les perméases semblent très peu conservées dès lors que l'on considère d'autres organismes que les \
Doctorat en Sciences
info:eu-repo/semantics/nonPublished
Hagan, G. Nana. "Adipocyte Insulin-Mediated Glucose Transport: The Role of Myosin 1c, and a Method for in vivo Investigation: A Dissertation." eScholarship@UMMS, 2008. https://escholarship.umassmed.edu/gsbs_diss/403.
Повний текст джерелаSales, Maria Carmen Oliveira Pinho de. "Regulação da expressão do transportador de aminoácidos de Leishmania (Leishmania) amazonensis." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/99/99131/tde-23022015-081238/.
Повний текст джерелаLeishmania presents two morphologically distinct forms in its life cycle: promastigote and amastigote. The promastigotes live in the midgut of the sand fly vector under the conditions of pH 7.0 and room temperature, around 25°C. The amastigote forms are found inside the phagolysosomes of infected macrophages where they encounter an environment of acidic pH and temperature around 34°C. Leishmania uses the arginine to synthesize polyamines which play an important role in cell growth, differentiation and in the successful of infection. The arginine uptake in Leishmania (L.) amazonensis is made by an amino acid porter 3-like protein (AAP3), coded by a two copies gene (5.1 aap3 e 4.7 aap3) arranged in tandem in the genome. The transcripts, 5.1 aap3 and 4.7 aap3, present 98% of ORFs identity, but differ in the 5\' and 3\' UTR. The aim of this work was to evaluate if canges in temperature, pH and arginine deprivation represent signals to trigger the regulation expression of aap3 in promastigotes and amastigotes. For this, we evaluated the transcripts level and performed assays of arginine uptake in parasites subjected to arginine starvation or supplemented with arginine, at temperatures of 25°C or 34°C and pH 7.0 or 5.0. In promastigotes we verified that the transcript 5.1 aap3 showed higher abundance in relation to 4.7 aap3, and that the arginine starvation promoted an increase in the amino acid uptake when the parasites were maintained at pH 7.0 and 25°C, confirming previous data from our group. The change of temperature was an important factor to the increase of 5.1 aap3 transcripts - in starved promastigotes, particularly when associated with pH 5.0. In addition, the increase of the temperature led to an increase of the arginine uptake, correlated to the increase of 5.1 aap3 transcript. The amastigotes-like maintained at 25°C and pH 7.0 and submitted to the amino acid starvation reverted 5.1 aap3 expression profile to the same observed for promastigotes. However, those condictions did not favor an increase in arginine uptake. The treatment of amastigotes at 34°C and pH 7.0 facilitated the increased of arginine uptake, but did not correlated with the transcripts level. The 4.7 aap3 transcript did not change significantly in any promastigotes and amastigotes treatments. Our results indicate that variation in temperature and pH, in addition to arginine starvation may be important signals for regulating the aap3 expression, mainly the copy 5.1 aap3, in order to ensure the correct supply of arginine in the previous period in relation to the entry of the promastigotes into the mammalian host or to the amastigotes transition in the vector, ensuring the success of the infection.
Abbadi, Mehdi. "Synthèse de marqueurs de la protéine de transport du D-glucose." Université Joseph Fourier (Grenoble), 1999. http://www.theses.fr/1999GRE10001.
Повний текст джерелаHarnevik, Lotta. "Molecular genetic studies on cystinuria." Doctoral thesis, Linköping : Univ, 2007. http://www.bibl.liu.se/liupubl/disp/disp2007/med1034s.pdf.
Повний текст джерелаPhelps, Mitch A. "Novel approaches for characterizing the riboflavin transport and trafficking mechanism and its potential as a target in breast cancer." Columbus, Ohio : Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1133261831.
Повний текст джерелаFrança, Moana Rodrigues. "Perfis endócrinos peri-ovulatórios influenciam o transporte, metabolismo e disponibilidade de aminoácidos no lúmen uterino de vacas de corte durante o diestro inicial." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/10/10131/tde-21032017-151159/.
Повний текст джерелаIn beef cattle, a large size of the pre-ovulatory follicle (POF) and resulting elevated proestrus/estrus estradiol (E2) and diestrus progesterone (P4) concentrations positively affect conceptus growth and fertility. However, sex-steroid-mediated mechanisms that influence uterine receptivity to the embryo need to be elucidated. Amino acids are important components of maternally-derived secretions that are crucial for embryo survival before implantation. The hypothesis is that the size of the POF, E2 and P4 concentrations modulate endometrial abundance of solute carrier proteins (SLC) transcripts related to AA transport and metabolism and subsequently affect lumenal amino acids concentrations. Therefore, follicle growth of Nelore cows was manipulated to produce two experimental groups: large POF and CL (LF-LCL group) and small POF and CL (SF-SCL group). On Day 4 (D4; Experiment 1) and Day 7 (D7; Experiment 2) post GnRH injection to induce ovulation, endometrial tissue and uterine washings were collected post-mortem. Transcript abundance was evaluated by qRT-PCR and amino acid concentrations were quantified in washings by HPLC. On Experiment 1, POF size, plasma E2 concentration on D-1, and plasma concentration of P4 on D4 were 15.70mm±0.43 vs. 11.31mm±0.23 (p<0.01), 2.44pg/ml±0.19 vs. 0.65pg/ml (p<0.01) and 1.40ng/ml±0.23 vs. 0.80ng/ml±0.10 (p<0.01) for the LF-LCL vs. SF-SCL groups, respectively. For Experiment 2, POF size, plasma E2 concentration on D-1 and plasma P4 concentration on D7 were 13.18mm±0.44 vs. 10.63mm±0.30 (p<0.01), 2.30pg/ml±0.57 vs. 0.50pg/ml±0.13 (p<0.01) and 3.68ng/ml±0.38 vs. 2.49ng/ml±0.43 (p=0.04) for the LF-LCL vs. SF-SCL groups, respectively. On D4, abundance of SLC6A6, SLC7A4, SLC17A5, SLC38A1, SLC38A7 and SLCY and on D7, SLC1A4, SLC6A1, SLC6A14, SLC7A4, SLC7A7, SLC7A8, SLC17A5, SLC38A1, SLC38A7, SLC43A2 and DDO was greater in the endometrium of cows from the LF-LCL group (p<0.05). On D4, higher concentrations of taurine, alanine and α-aminobutiric acid were observed in SF-SCL (p<0.05). In contrast, lower concentrations of valine and cystathionine were quantified in D7 uterine washings from SF-SCL cows (p<0.05). On D4, animals from LF-LCL group, associated with greater fertility, presented less amino acid content in uterine secretion but abundance of transporters was compatible to greater transport in comparison to animals from SF-SCL group. This suggests that before embryo moves from oviduct to uterus, amino acids transport and metabolism pathways prioritizes endometrium cells preparation for receiving the embryo but not accumulation in uterine secretions. However, on D7, when the embryo is in direct contact with uterine secretions, genes related to amino acids transport in endometrium and amino acids concentration in histotroph are up-regulated in LF-LCL cows. The latter insights indicate that amino acids metabolism and transport, towards endometrial cells or uterine secretions, might be mechanisms contributing to maternal receptivity.
Benba, Jamila. "Contribution à l'étude du système de transport des dicarboxylates des mitochondries; purification, caractérisation." Rouen, 1993. http://www.theses.fr/1993ROUES053.
Повний текст джерелаDuvic, Bernard. "Purification et etude de la proteine de transport de la 20-hydroxyecdysone chez un insecte : locusta migratoria." Université Louis Pasteur (Strasbourg) (1971-2008), 1988. http://www.theses.fr/1988STR13160.
Повний текст джерелаFernandes, Carla Freire Celedonio. "Molecular characterization and expression of two new members of the SLC10 transporter family: SLC10A4 and SLC10A5." Giessen VVB Laufersweiler, 2007. http://d-nb.info/987398539/04.
Повний текст джерелаDesruet, Marie-Dominique. "Étude de traceurs radioactifs pour l'évaluation in vivo de la densité des transporteurs membranaires du glucose." Université Joseph Fourier (Grenoble), 1996. http://www.theses.fr/1996GRE10251.
Повний текст джерелаAdrait, Annie. "Etudes spectroscopiques et magnétiques de la protéine Fur (Ferric Uptake Regulation) d'Escherichia coli." Université Joseph Fourier (Grenoble), 1998. http://www.theses.fr/1998GRE10212.
Повний текст джерелаIden, Janne. "Assoziation der 2319-A-Variante des Dopamin-Transporter-Gens (DAT1) mit geringer Alkoholtoleranz /." Berlin : Lehmanns Media, 2008. http://d-nb.info/991659619/04.
Повний текст джерелаGoetz, David Henry. "Neutrophil gelatinase-associated lipocalin : a protein involved in immune defense against microbial pathogens /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/4991.
Повний текст джерелаMatsui, Yuto. "Visualization of procollagen IV reveals ER-to-Golgi transport by ERGIC-independent carriers." Kyoto University, 2020. http://hdl.handle.net/2433/259728.
Повний текст джерелаRoux, Pierre. "Le transporteur mitochondrial des adénine-nucléotides de la levure Saccharomyces cerevisiae : relations structure-fonction." Université Joseph Fourier (Grenoble), 1997. http://www.theses.fr/1997GRE10228.
Повний текст джерелаDuplay, Pascale. "Approche genetique de la topologie fonctionnelle de la proteine affine du maltose chez escherichia coli." Paris 7, 1987. http://www.theses.fr/1987PA077001.
Повний текст джерелаDeWit, Ralph. "Multimodal transport : carrier liability and documentation /." London [u.a.] : Lloyd's of London Press, 1995. http://www.gbv.de/dms/spk/sbb/recht/toc/278603084.pdf.
Повний текст джерелаWatling, Jeremy Richards. "Carrier transport in quantum well structures." Thesis, University of East Anglia, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267463.
Повний текст джерелаBöhm, Andreas. "Imaging of light induced carrier transport." [S.l. : s.n.], 2002. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB9820898.
Повний текст джерелаDalbon, Pascal. "La protéine mitochondriale de transport des adénine-nucléotides : localisation des sites nucléotidiques par photomarquage, étude de la topographie membranaire de la chaîne polypeptidique à l'aide d'anticorps anti-peptides synthétiques." Grenoble 1, 1987. http://www.theses.fr/1987GRE10121.
Повний текст джерелаRobinson, Robert Charles. "Horse plasma vitamin D-binding protein : isolation and structural investigation." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/30292.
Повний текст джерелаScience, Faculty of
Chemistry, Department of
Graduate
Naudon, Laurent. "Recherche d'une participation du transporteur neuronal de la dopamine et du transporteur vésiculaire à l'adaptation neuronale." Rouen, 1994. http://www.theses.fr/1994ROUES066.
Повний текст джерела