Дисертації з теми "Cancer in children Epidemiology"
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KRALLMAN, KELLI ALICIA. "The Cancerogenic Effects of Exposure to Uranium: Are Children More At Risk?" University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1218647724.
Повний текст джерелаDavis, Jonathan. "Cancer risk in children of agricultural health study participants." Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/5926.
Повний текст джерелаDang-Tan, Tam 1976. "Epidemiology of delays in care of children and adolescents diagnosed with cancer in Canada." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=115664.
Повний текст джерелаStudy Design: I conducted a prospective cohort study to investigate the delays of cancer symptoms reporting, diagnosis, and treatment in children between 0-19 years of age in Canada. This study used a database from Health Canada's Treatment and Outcomes component of the Canadian Childhood Cancer Surveillance and Control Program.
Methodology: Patients were identified from 17 paediatric cancer centres across Canada. Subjects included in this study were residents of Canada, aged less than 20 years, diagnosed with a malignant tumour and had information on date of first symptoms, diagnosis, treatment and outcome available. Descriptive statistics and regression techniques (linear, logistic and Cox regression) were used as appropriate. I measured the individual impact of patient and provider delays on disease severity and prognosis by using judicious control for potential confounding mechanisms and mediating factors.
Study Findings and Significance: By measuring various types of delays in Canada, I found that varying lengths of patient and referral delay, across age groups, types of cancers, and Canadian settings, are the main contributors to diagnosis, HCS and overall delay. Factors relating to the patients, the parents, healthcare and the cancer may all exert different influences on different segments of cancer care. I also found a negative association between diagnosis delay and disease severity for lymphoma and CNS tumour patients. Furthermore, I found that diagnosis and physician delay had a negative effect, while patient delay had a positive effect, on survival for patients diagnosed with CNS tumours. The information provided from this study may form the basis for new effective policies aimed at eliminating obstacles in cancer the diagnostic and care trajectories for Canadian children with cancer and for improving their prognosis.
Oliveira, Friestino Jane Kelly 1984. "Panorama do câncer em crianças e adolescentes sob a perspectiva da Saúde Coletiva = Overview of cancer among children and adolescents in the perspective of Collective Health." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312569.
Повний текст джерелаTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas
Made available in DSpace on 2018-08-27T20:51:08Z (GMT). No. of bitstreams: 1 OliveiraFriestino_JaneKelly_D.pdf: 2892489 bytes, checksum: fdc2a35ce3e46aaf292c913864bc673d (MD5) Previous issue date: 2015
Resumo: A assistência à saúde da criança e adolescente necessita contemplar as particularidades e características intrínsecas a essa fase da vida. Os cânceres que acometem crianças e adolescentes têm fatores de riscos e características que diferem daqueles que acometem a população adulta. No Brasil, pouco se conhece a respeito da magnitude das neoplasias no universo infanto-juvenil, bem como as características da população acometida. Objetivou-se estudar o panorama do câncer em crianças e adolescentes sob a perspectiva da Saúde Coletiva, e neste âmbito, apontar ferramentas de monitoramento; conhecer as dificuldades e percepções dos profissionais de saúde que atuam na atenção básica, em relação a suspeita e diagnóstico de câncer em crianças; e, analisar os padrões de distribuição espacial das incidências e sobrevivências de crianças diagnosticadas com neoplasias. Para atender aos objetivos, foram utilizados métodos qualitativos e quantitativos com dados obtidos em Registros de Câncer de Base Populacional e também em Grupos Focais realizados com trabalhadores da Atenção Primária à Saúde. Os resultados foram apresentados em capítulos correspondentes a três artigos. No primeiro artigo, "Câncer Infantil: monitoramento da informação através dos Registros de Câncer de Base Populacional RCBP", realizou-se uma pesquisa bibliográfica da incidência de tumores raros em menores de 20 anos, em três países. Nesta busca identificou-se que a primeira publicação específica sobre câncer em crianças e adolescentes no Brasil foi divulgada em 2008. As publicações do Brasil, Alemanha e Estados Unidos apresentam as informações com critérios heterogêneos, tanto em relação ao modo como a incidência é apresentada, quanto em relação à faixa etária adotada. No segundo trabalho, "Suspeita e Diagnóstico de Câncer em Crianças e Adolescentes na Atenção Primária à Saúde", foram identificados pontos fortes e fragilidades no que concerne ao sentimento dos profissionais; a suspeita e diagnóstico na rede de cuidados primários e a relação dos profissionais e a família. Em todas as categorias de profissionais, as percepções foram negativas com demonstração de insegurança em relação ao tema na atenção básica. No terceiro estudo, "Câncer em crianças e adolescentes: incidência e sobrevivência no município de Campinas-SP, Brasil", os resultados apontaram taxa de incidência global para os grupos de Leucemias (Grupo I); Linfomas (Grupo II); Tumores do Sistema Nervoso Central (Grupo III) e Sarcomas de Partes Moles (Grupo IX) de 54,2 por milhão, com uma incidência padronizada de 59,1 por milhão (Grupo I¿28,8; Grupo II-11,6; Grupo III-7.5 e Grupo IX-4,3). Diferenças nos padrões espaciais não foram encontradas. Diferenças significativas em tempos de sobrevivência foram verificadas por Grupos de diagnóstico ajustados para idade e sexo (p=0,001). Os achados desse estudo demonstraram diferentes possibilidades de abordagem do câncer infantil utilizando o saber científico da Epidemiologia. Os resultados apontam para a necessidade de uma sistematização das informações de tumores raros na infância e na adolescência, e uma inclusão do tema câncer infantil aos profissionais de saúde que atuam na Atenção Primária à Saúde. A utilização de metodologias epidemiológicas como análise da incidência, uso da estatística espacial e análises de sobrevivência contribuem para a construção do panorama do câncer infantil na Saúde Coletiva.
Abstract: The health care to the children and adolescents needs to contemplate the particularities and intrinsic characteristics of this phase of life. Occurrences of childhood cancer have risk factors and specific characteristics that differ from tumours in adults. In Brazil, little is known about the magnitude of childhood cancer, as well as the characteristics of the affected population. Our goal to study cancer among children and adolescents in the perspective of Collective Health, and in this context, point monitoring tools in the health information systems; identify the difficulties and perceptions of workers in primary health care, in relation to suspicion and diagnosis of childhood cancer; and finally analyse the distribution patterns of spatial incidence and survival of children who have been diagnosed with cancer. To achieve the objectives, we used qualitative and quantitative methods with data by Population-based Cancer Registries and also in focus groups conducted with workers of Primary Health Care. Results are presented in three articles on chapters. In the first article, "Childhood Cancer: Information Followed in Population-Based Cancer Registry", we conducted a literature search of tumours incidence in children under 20 years of age in three countries. This research identified that first specific publication about cancer among children and adolescents in Brazil was released in 2008. Publications of Brazil, Germany and the United States have the information with heterogeneous criteria, both in relation to how the incidence is presented and in relation to age adopted, being difficult to compare. In the second study, "Suspicion and Diagnosis of Cancer among Children and Adolescents in Primary Health Care", were identified strong points and weaknesses concerning regarding feeling of professionals, suspicion and diagnosis the primary care network and relationship between professionals and family. In all professional¿s categories perceptions were negative with demonstration of insecurity in primary care. In the study, "Cancer Incidence and survival among children and adolescents in Campinas ¿ SP, Brazil", the results showed overall crude incidence rate for Leukaemia (Group I); Lymphomas (Group II); CNS neoplasms (Group III), and Soft tissue sarcomas (Group IX) was 54.2 per million and standardized incidence rates was 59.1 (Group I-28.8, Group II-11.6, Group III-7.5 and Group IX-4.3). Spatial differences were not found. Significant differences in survival times were found by diagnostic Groups adjusted for age and sex (p=0.001). In conclusion, higher incidence was found in Group-I and 5-year survival is higher in children than in adolescents similar to the findings reported in the literature. The findings of this study showed different approach possibilities of childhood cancer using scientific knowledge of collective health. The results indicate the need for systematic information of rare tumours in childhood, and including the theme to health professionals working in primary health care. The use of such epidemiological methods analysis of incidence, use of spatial statistics and survival analyses contribute to the construction of the panorama of childhood cancer in Collective Health
Doutorado
Epidemiologia
Doutora em Saúde Coletiva
Kroll, Mary Eileen. "Time trends in childhood cancer : Britain 1966-2005." Thesis, University of Oxford, 2009. http://ora.ox.ac.uk/objects/uuid:8be887be-36e7-4b77-a7af-5887f3a1df8c.
Повний текст джерелаTanaka, Luana Fiengo. "A epidemiologia do câncer em crianças e adolescentes com Aids no Município de São Paulo: um estudo de base populacional." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/6/6132/tde-18042017-150014/.
Повний текст джерелаIntroduction: The association between human immunodeficiency virus (HIV) infection and cancer has been documented since the beginning of the epidemic of the acquired immunodeficiency syndrome (AIDS). The introduction of the highly active antiretroviral therapy (HAART) has profoundly altered the course of the AIDS epidemic, drastically reducing the incidence of AIDS-defining manifestations, including cancers. Nevertheless, there is limited information on the incidence of cancer in children and adolescents with AIDS living in developing countries. Objective: To describe the cancer epidemiology in children and adolescents with AIDS in the Municipality of São Paulo from 1997 to 2012. Methods: It is a population-based study, using the databases of the Population-based Cancer Registry of São Paulo and the Notifiable Diseases Information System (SINAN). Children and adolescents (< 20 years) with AIDS and cancer have been identified by means of a probabilistic record linkage process between the aforementioned databases. Crude and age-standardized incidence rates per million inhabitants were calculated. To compare the incidence of cancer in people with AIDS and that of the general population, standardized incidence ratio (SIR) and respective 95 per cent confidence intervals (95 per cent CI) were calculated. We examined trends by calculating the annual percent change (APC) and corresponding 95 per cent CI. The analyses of the overall five-year survival after cancer diagnosis among children and adolescents with AIDS and that of the general population were based on the Kaplan-Meier product limit estimator and univariate Cox proportional hazards models. Choropleth maps on monochromatic scales were generated to describe the distribution of cases across the Municipality. Results: We identified 24 cases of cancer in patients with AIDS aged 20 years and younger, of which, 62.5 per cent were AIDS-defining malignancies. The most incident cancers were non-Hodgkin\'s lymphoma, including Burkitt\'s lymphoma (12; 50.0 per cent ), Hodgkin\'s lymphoma (6; 25.0 per cent ) and Kaposi sarcoma (3; 12.5 per cent ). The age-standardized incidence rate was 1,461.3 cases/million. The trend analyses revealed a significant reduction in the incidence of all cancers (APC= -14.5), driven by the decrease in AIDS-defining cancers (APC= -17.0). The overall risk for cancer was significantly increased (SIR= 3.9), especially for non-Hodgkin lymphoma, excluding Burkitts lymphoma (SIR= 22.5), Burkitt\'s lymphoma (SIR= 29.7) and Hodgkin\'s lymphoma (SIR= 18.7). The overall probability of survival at five years after cancer was 56.3 per cent in children and adolescents with AIDS versus 87.5 per cent in the general population. The hazard ratio for death was 5.2 (95 per cent CI= 2.0, 13.6). The map of the geographical distribution showed a concentration of cases in the low-income areas of the Municipality. Conclusion: There was a marked reduction in the incidence of AIDS-defining cancers, likely to be a result of the introduction of HAART. However, children and adolescents with AIDS remain at increased risk for the development of cancer when compared to the general population. For those who developed cancer, the risk of death was also significantly higher
Wiklund, Fredrik. "Genetic epidemiology of prostate cancer." Doctoral thesis, Umeå : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-281.
Повний текст джерелаCheng, Kar Keung. "The epidemiology of oesophageal cancer." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309275.
Повний текст джерелаRigby, Janette Elizabeth. "An epidemiology of breast cancer." Thesis, Lancaster University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311870.
Повний текст джерелаMacfarlane, Gary John. "The epidemiology of oral cancer." Thesis, University of Bristol, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357309.
Повний текст джерелаGandini, Sara. "Meta-analysis in cancer epidemiology." Thesis, University of Birmingham, 2004. http://etheses.bham.ac.uk//id/eprint/251/.
Повний текст джерелаKho, Pik Fang. "Genetic epidemiology of endometrial cancer." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/211383/1/Pik%20Fang_Kho_Thesis.pdf.
Повний текст джерелаJi, Jia. "Translational Research in Cancer: Preclinical Pharmacodynamics and Cancer Epidemiology." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1250092164.
Повний текст джерелаPlummer, Kathleen Hope. "Cancer and Infection." Scholar Commons, 2014. https://scholarcommons.usf.edu/etd/5293.
Повний текст джерелаLubbe, Steven John. "The genetic epidemiology of colorectal cancer." Thesis, Institute of Cancer Research (University Of London), 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538696.
Повний текст джерелаMichelin, Ruel Slyfield. "The Effect of Phytoestrogen Chemoprevention of Prostate Cancer." ScholarWorks, 2011. https://scholarworks.waldenu.edu/dissertations/1064.
Повний текст джерелаPersson, Eva-Karin. "Hydrocephalus in children : epidemiology and outcome /." Göteborg : Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy at Göteborg University, 2007. http://hdl.handle.net/2077/2556.
Повний текст джерелаOlsen, Jonathan Robin. "Epidemiology of molluscum contagiosum in children." Thesis, Cardiff University, 2015. http://orca.cf.ac.uk/70412/.
Повний текст джерелаTran, Sinh. "Tuberculosis in children : diagnosis and epidemiology." Thesis, Open University, 2017. http://oro.open.ac.uk/48426/.
Повний текст джерелаStella, Achimole. "Epidemiology peculiarities of poisoning of children." Thesis, Сумський державний університет, 2013. http://essuir.sumdu.edu.ua/handle/123456789/32300.
Повний текст джерелаWatson, Joanna. "Studies in the epidemiology of colorectal cancer." Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.534176.
Повний текст джерелаFord, Deborah. "Genetic epidemiology of breast and ovarian cancer." Thesis, Institute of Cancer Research (University Of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367527.
Повний текст джерелаBolton, Kelly. "The genetic epidemiology of ovarian cancer survival." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610071.
Повний текст джерелаMacdonald, Sara. "An exploration of lay epidemiology and cancer." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2583/.
Повний текст джерелаMungai, Mary Wairimu. "The epidemiology of atopy in Kenyan children." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ29756.pdf.
Повний текст джерелаMungai, Mary. "The epidemiology of atopy in Kenyan children /." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=27381.
Повний текст джерелаWhen the urban rural differences were adjusted for these differences in the distribution of personal, environmental and socio economic characteristics, the odds ratio fell to 0.81 and became nonsignificant (95% CI 0.50 to 1.33). Therefore, the urban rural difference in the prevalence of atopy in Kenyan children appear to be due to the differences in the distribution of the relevant risk factors.
Hemingway, Jennifer M. "Low Level Lead Exposure and Postural Balance in Children." University of Cincinnati / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1353099859.
Повний текст джерелаTheodoratou, Evropi. "Colorectal cancer and diet in Scotland." Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/3287.
Повний текст джерелаMacLeod, Kendra D. "Emotional well-being in children experiencing cancer and children whose mother experiences cancer /." Cincinnati, Ohio University of Cincinnati, 2005. http://www.ohiolink.edu/etd/view.cgi?acc%5Fnum=ucin1128615655.
Повний текст джерелаPuig, Vives Montserrat. "Breast cancer epidemiology: mammographic screening and molecular subtypes." Doctoral thesis, Universitat de Girona, 2015. http://hdl.handle.net/10803/289426.
Повний текст джерелаL’objectiu d’aquesta tesi és realitzar aprofundir en diversos aspectes de l'epidemiologia del càncer de mama. Hem confirmat que la incidència del DCIS a Girona ha augmentat en les últimes dècades. Les proporcions dels càncers detectats mitjançant el programa de cribratge, fora d’aquest i els càncers d'interval van ser del 42,2%, 52,2% i 5,8%, respectivament. Per altra banda, el subtipus amb la supervivència més elevada i més baixa van ser el luminal A-like i el triple negatiu, respectivament. És important destacar que el subtipus molecular de càncer de mama definit per biomarcadors determinats amb tècniques d’IHC proporciona valor pronòstic, independentment de l'edat, la mida, el grau histològic, l’afectació dels ganglis i el mètode de detecció. Finalment, hem demostrat que el mètode de detecció del càncer també proporciona valor pronòstic independentment de l'edat, la mida, el grau histològic, l'afectació dels ganglis i el subtipus molecular.
Sak, Sei Chung. "Molecular epidemiology of DNA repair and bladder cancer." Thesis, University of Leeds, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.446441.
Повний текст джерелаKellier, Nicole. "The Epidemiology of Prostate Cancer Among Multiethnic Men." FIU Digital Commons, 2011. http://digitalcommons.fiu.edu/etd/534.
Повний текст джерелаSiliņš, Ilvars. "Molecular epidemiology of human papillomavirus and cervical cancer /." Stockholm : [Karolinska institutets bibl.], 2001. http://diss.kib.ki.se/2001/91-7349-091-1/.
Повний текст джерелаMagnusson, Cecilia. "Breast cancer epidemiology : influence of hormone-related factors /." Stockholm, 1998. http://diss.kib.ki.se/1998/91-628-2870-3.
Повний текст джерелаBashash, Morteza. "Molecular epidemiology of gastric and esophageal cancer survival." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/30666.
Повний текст джерелаWebb, Penelope M. "The epidemiology of Helicobacter pylori and gastric cancer." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259836.
Повний текст джерелаConway, David Ian. "Epidemiology of oral cancer from a socioeconomic perspective." Thesis, University of Glasgow, 2008. http://theses.gla.ac.uk/154/.
Повний текст джерелаFranklin, Jarrod Peter. "Epidemiology of cancer in patients with inflammatory polyarthritis." Thesis, University of Manchester, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.517729.
Повний текст джерелаPrice, Alison Jane. "Nutritional and hormonal biomarkers in prostate cancer epidemiology." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:8d96d746-7c87-4133-b873-e9a8426da953.
Повний текст джерелаSchmidt, Julie Andersen. "Epidemiology of metabolite profile and prostate cancer risk." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:468ca322-16a3-4f61-8fcc-bac9b918300c.
Повний текст джерелаAkre, Olof. "Etiological insights into the testicular cancer epidemic /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3689-7/.
Повний текст джерелаMytton, Julie Ann. "Epidemiology of injuries in primary school aged children." Thesis, University of the West of England, Bristol, 2011. http://eprints.uwe.ac.uk/20897/.
Повний текст джерелаHijazi, Nariman. "Epidemiology of asthma among children in Saudi Arabia." Thesis, University of Aberdeen, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322584.
Повний текст джерелаNortham, Emma J. K. "The epidemiology of diabetes in very young children." Thesis, University of Bristol, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284899.
Повний текст джерелаChen, Maxine M. "Genetics and Genomics of Endometrial Cancer." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:27201719.
Повний текст джерелаGarrett, Amy. "Characteristics of Death Certificate Only Cases in the Cancer Registry." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1405704511.
Повний текст джерелаLewis, Sylvester. "Dissertation: Sociodemographics and Pancreatic Cancer Survival Rate." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/5745.
Повний текст джерелаNdui, Mary K. "Epidemiology of oral cancer in South Africa 1996-2002." Thesis, University of the Western Cape, 2011. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_8665_1367481245.
Повний текст джерелаOral cancer is characterised by marked geographical differences in frequency and site preference as reported by various studies. In South Africa, a few studies have been reported on the patterns and aetiology of oral cancer, and age standardised incidence rates (ASIR). Studies in several countries have shown an increase in oral cancer incidence among younger people. Title: 
Epidemiology of oral cancer in South Africa 1996-2002. 
Aim and Objective: The aim of this study was to determine the age standardised incidence rates (ASIR) of oral cancer by age, gender, race 
and site in South Africa for a consecutive period of seven years. Method: Pathology case records of oral cancer diagnosed over a seven-year period from 1996 to 2002 and reported to the National 
Cancer Registry (NCR) were analysed for age, sex, race, and date of diagnosis, basis of diagnosis, topography and tumour type. The data was tabulated and categorised using Microsoft Excel. The South African population size for each year of the study was estimated by linear extrapolation using the 1996 and 2001 census results. Age standardisation incidence rates against the world 
population were calculated by the standard direct method. Results: The total number of oral squamous cell carcinoma cases over the 7-year period was 9702. The majority of cases (34%) were 
on the tongue. The male to female ratio was 1:3. The age standardized incidence rates in this study was lower among African women
(0.640 per 100000 per year) and the highest was 13.40 new cases per 100000 per year (coloured males). Lip cancer was highest among both males and females of the white population. The cumulative rate of developing oral cancer was 1:83 and 1:32 for males and females respectively.
Key, Timothy J. A. "Studies in the epidemiology of sex hormones and cancer." Thesis, University of Oxford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238136.
Повний текст джерелаPorter, Daniel Edward. "Studies on the genetic epidemiology of heritable breast cancer." Thesis, University of Edinburgh, 1995. http://hdl.handle.net/1842/21467.
Повний текст джерела