Дисертації з теми "Cancer identity"
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Masson, Sarah Jane. "Identity, meaning making and cancer survivorship." Thesis, University of Exeter, 2014. http://hdl.handle.net/10871/15372.
Повний текст джерелаNg, Tsz-yin Carina. "Illness, ideology, and identity the "pregnancy" of cancer /." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38671074.
Повний текст джерелаNg, Tsz-yin Carina, and 伍紫燕. "Illness, ideology, and identity: the "pregnancy" of cancer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B38671074.
Повний текст джерелаPalmer-Wackerly, Angela Lynn. "Illness Identity, Social Support, and Cancer Treatment Decision-Making." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1434452561.
Повний текст джерелаvan, Willigen Marieke Minke. "Collective identity and activist strategies in the breast cancer movement." The Ohio State University, 1993. http://rave.ohiolink.edu/etdc/view?acc_num=osu1382032315.
Повний текст джерелаDuvall, Kathryn L., Kelly A. Dorgan, and Sadie P. Hutson. "Personal Identity Changes of Female Cancer Survivors in Southern Appalachia." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/etsu-works/1228.
Повний текст джерелаMourão, Larissa. "Unravelling the identity and fate of Notch1-expressing cells within intestinal tumours." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066586/document.
Повний текст джерелаLes cellules souches et le cancer sont inextricablement liés et de nombreuses tumeurs, y compris les cancers colorectaux, contiennent une petite population de cellules auto-renouvelables, appelées cellules souches cancéreuses (CSCs), capables de donner naissance à des cellules proliférantes mais progressivement différenciatrices qui contribuent à l'hétérogénéité cellulaire typique des tumeurs solides. Ainsi, l'identification des CSC et des facteurs qui régissent leur comportement devrait avoir un impact profond sur le traitement du cancer. Notch signale le contrôle le maintien et la différenciation des cellules souches dans plusieurs tissus, y compris l'intestin, où elles sont essentielles au maintien des cellules souches. Sur la base de ces prémisses, mes travaux visaient à identifier et caractériser les cellules qui expriment le récepteur Notch1 dans les tumeurs intestinales in vivo, dans le but de mieux comprendre la hiérarchie cellulaire des cellules cancéreuses du colon. Nous avons constaté que le récepteur Notch1 s'exprime dans de rares cellules tumorales indifférenciées qui se renouvellent et se multiplient in vivo, car elles donnent lieu indéfiniment à une différenciation marquée des cellules tumorales et à une croissance tumorale. Notre analyse du profil transcriptomique de ces cellules a confirmé nos observations in vivo selon lesquelles les cellules tumorales Notch1+ représentent une population spécifique de cellules tumorales hautement prolifératives, exprimant plusieurs marqueurs connus, mais pas tous, des cellules souches intestinales normales (CSI). En effet, leur signature transcriptionnelle est fortement corrélée avec les CSI normaux. Étant donné que les cellules tumorales que nous avons caractérisées ne semblent pas être porteuses de mutations Apc, nous supposons que durant les premières étapes de la tumorigénèse, les CSI normales Notch1+ sont englouties dans la tumeur naissante (dans des cryptes hyperprolifératives aberrantes) et sont capables de croître et de s'étendre dans ce nouvel écosystème, car elles sont soutenues par les facteurs de croissance extrinsèques des cellules mutantes voisines. Le concept selon lequel les CSI normaux pourraient contribuer à l'expansion tumorale met en évidence les complications que les patients peuvent rencontrer pendant le traitement, puisque ces cellules partagent de nombreuses caractéristiques avec leurs homologues de type sauvage, ce qui rend le traitement délétère pour les CSI normaux
Soltermann, Tanya C. "Emergence of a Cancer Identity in Emerging Adulthood: Weblogs as Illness Narratives." Thèse, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/30653.
Повний текст джерелаDuvall, Kathryn L. "Surviving Cancer in Appalachia: A Qualitative Study of Family Cancer Communication and Changing Personal Identities Through the Cancer Journey." Digital Commons @ East Tennessee State University, 2010. https://dc.etsu.edu/etd/1677.
Повний текст джерелаReiter, Paul Lawrence. "Appalachian Self-Identity, Cervical Cancer Screening, and Risky Sexual Behavior Among Women in Ohio Appalachia." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1210958568.
Повний текст джерелаPrinsloo, Erna Louisa. "From victims to warriors: collective identity construction at cancer movement assemblies in South Africa." Doctoral thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/16684.
Повний текст джерелаInterest in this topic was awakened by the rapid growth of Relay For Life in South Africa and its striking ability to bond people during mass cancer gatherings. Questions were raised about the generation of collective identities during these assemblies, the nature of the activated identities, and how these relate to the broader debates about cancer and identity. This inquiry investigates the unexplored intersection of cancer and identity in the context of a burgeoning solidarity movement that has found a strong following countrywide. A contemporary hermeneutic perspective allowed a dual focus on the micro-sociological dimensions and the structural elements that converge to generate collective identities at assemblies. A theoretical scheme was synthesized out of the work of theorists who deal with collective identity, spaces set aside for people in crisis, social interaction during focused gatherings and illness narratives. A non-comparative case study was used to investigate the phenomenon at 20 cancer assemblies. Short-term ethnography, focus group interviews, photographs and YouTube videos provided the data that was analysed using the hermeneutic circle of interpretation. The findings showed that personal illness identities and situation-specific role identities interact with a potent cocktail of elements - ephemeral space, a shared focus on cancer, collective action, illusion and emotions - to activate three symbolic identities: a dominant collective identity that relies on heroic warrior mythology, a secondary collective identity that draws upon a transformation ideal, and a hidden identity which has its roots in the notion of being wounded. It is argued that assemblies rely on a dominant collective identity which is symbolic in nature and imposed on participants by the cancer movement. Participants are portrayed as positive, hopeful heroic warriors tasked with vanquishing cancer. Although ubiquitous at cancer assemblies, the dominant collective identity is nevertheless sufficiently fluid to allow a measure of hybridization, inversion and contestation. This inquiry gives credence to other work on cancer and identity which recognizes that the dominant identity provides benefits not offered by a victim representation. It also expresses reservations about the wisdom of expecting affected people to maintain a brave exterior in the face of an illness that causes emotional disequilibrium.
Furlan, Giacomo. "Deciphering changes in cellular identity during development, reprogramming and oncogenesis." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE1309.
Повний текст джерелаIn the classical view of development, changes of cellular identity take place only during differentiation. In this process, the pluripotent stem cell, a cell capable of forming the whole organism, differentiates ultimately in specified somatic cells. This differentiation is always accompanied by an increasing loss of cellular plasticity, which is the ability to give rise to multiple cell type, and acquisition of specific features and characteristics typical of the new cell. New advances in the developmental biology proved this wrong, showing that cells more advanced in the developmental path can revert to less differentiated states. Already in the pluripotent compartment of the embryo, cells more committed can go back to more naïve states, and the processes are convertible, showing the plasticity of the differentiation process. During my PhD, I identified the ligand Netrin-1 and its receptors Neo-1 and Unc5-b as novel regulators of naïve states. Moreover, a differentiated somatic cell can reacquire cellular plasticity and revert to the pluripotent state, giving rise to induced pluripotent stem cells (iPSCs), or, in a pathological context, the reacquisition of plasticity can anticipate the malignant transformation and cancer formation. As a second project of my PhD, I identified the axis c-Myc/Atoh8/Wnt as a pathway orchestrating iPSCs generation and malignant transformation
Pearce, Susie. "A narrative study exploring representations of identity for young adults with cancer : from diagnosis through treatment." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10047462/.
Повний текст джерелаZouggar, Aïcha. "G9a/EHMT2 Methyltransferase Activity Controls Stem-Like Identity and Tumor-Initiating Function in Human Colorectal Cancer." Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/41821.
Повний текст джерелаWallqvist, Marika, and Evelina Pettersson. "Att förlora ett bröst- att förlora en del av sig själv : En litteraturbaserad studie." Thesis, Högskolan i Skövde, Institutionen för hälsa och lärande, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-9356.
Повний текст джерелаBreast cancer is the most common form of cancer among women in Sweden. Mastectomy is a common treatment for breast cancer. It is a surgical procedure where the whole breast is removed. Losing a breast can affect a woman’s body image and identity. The aim of this literature-based study was to describe how women treated with mastectomy experience themselves after the surgery, regarding body image and identity. The method used is a qualitative literature-based study based on eleven articles with qualitative approach. The results show that women undergoing mastectomy feel a loss of more than a physical body part. The women misses a significant marker for femininity and experienced that their altered bodies becomes deformed. Their body becomes estranged and their sexuality will be affected, the women may also experience a social deviation due to their changing body. The study shows that when the woman's identity and body image is affected, she experiences severe suffering. It is important that the nurse has knowledge of the experiences that can occur after a mastectomy. The nurse has a key responsibility when meeting women, to guide her through the treatment process so that the woman can find an understanding and acceptance about the changing body.
Lindbäck, Jenny, and Sandra Nordén. "Kvinnors upplevelse av en förändrad identitet vid bröstcancer och dess behandling." Thesis, Umeå universitet, Institutionen för omvårdnad, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-116679.
Повний текст джерелаBackground: Breast cancer is the most common form of cancer among women. To suffer through breast cancer and the treatment of it is affecting woman in many ways. Aim: To describe women’s experience of a changed identity when facing breast cancer and its treatment. Method: A literature-based study composed by twelve qualitative articles analyzed with manifest content analysis. Database searching via Cinahl, PubMed and PsykINFO. Results: Breast cancer and its treatment is a challenge for the physical integrity and can be seen as a threat to femininity. Three main categories were identified: an existential identity crisis, the loss of former identity and the meeting of others with altered identity. Discussion: Brought up is how the treatment and side-effects affect women. How the changing body threatens femininity and gender role is also discussed. Society’s stereotypical images of what is feminine make it difficult for women to lose hair or a breast. Conclusion: To be diagnosed with breast cancer brings up many emotions and will affect women for a long time. More research in the area could help these patients to cope with the changes that the cancer and its treatment involves.
Johnston, Dawn. "Renegotiating the self : how eight women diagnosed with breast cancer re-shaped a sense of self-identity." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/44304.
Повний текст джерелаKorfi, Koorosh. "Epigenetic programming defines stem cell identity and entry into the proliferative compartment in chronic myeloid leukaemia (CML)." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/3929/.
Повний текст джерелаMelo, E. Silva Francilene Maria De. "Identité, Travail et Genre en psychosomatique : à propos du cancer du sein." Thesis, Paris, CNAM, 2013. http://www.theses.fr/2013CNAM0865.
Повний текст джерелаThe present thesis is based on the clinical evolution of patients treated for breast cancer. The painfull experience engendered by the pathology and its treatment leads to transformation of their approach to work activity. These transformations induce these women patients to examine their approach to their erogenous body, their work activity and their sexual identity. Thereby the double feature of work activity (Arbeit/Poïesis), based on restoring their erogenous body in relation with work activity, is revealed as playing the major role in the psychological restoration and the settled remission process of breast cancer. Inspired by this new point of view based on experimentation in the Laboratory of Psychodynamics of Work in the CNAM (Centre national des Arts et Métiers), we decided to base our research on the contribution that Psychodynamics or Work methodology and closely connected domains could comply with our proposal for a new psychosomatic treatment of breast cancer, precisely by analysing the connection between soma and work activity in the psychological treatment for these women patients concerned. Hereafter, we argue for a psychological treatment based on the subjective approach to work activity, thus enabling our patients to conquer a new sexual identity in an uninhibited erogenous body
Widholm, Boström Emma, and Mirjam Granberg. "Kvinnors upplevelser av att leva med bröstcancer : En litteraturöversikt." Thesis, Ersta Sköndal Bräcke högskola, Institutionen för vårdvetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:esh:diva-7889.
Повний текст джерелаMulder, Anja. "Women's lived experiences of the breast cancer trajectory: the waiting period for treatment and the impacts on feminine identity." Thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/2661.
Повний текст джерелаHitchins, Jennifer Marie. "Posttraumatic growth as a discursive resource for managing identity after breast cancer : implications for theory, and counselling psychology practice." Thesis, London Metropolitan University, 2015. http://repository.londonmet.ac.uk/695/.
Повний текст джерелаAcosta, Suárez Esther Gloria. "Expériences de cancers urogénitaux au masculin : une approche socio-anthropologique." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAG026.
Повний текст джерелаThis thesis is concerned with the experiences lived by men who have been diagnosed and treated with a urogenital cancer (prostate, bladder and testicles) in the Spanish local context of one of the seven Canary Islands. The research instruments which have been used were particularly interviews with people who have experienced the process of these forms of cancer with the aim of understanding how they felt throughout the trajectory, from the appearance of the first symptoms and/or signs which led them to medical institutions, up to the experiences lived at the time of receiving the diagnosis and the announcement of the biomedical treatments, and finally the ways of experiencing these treatments (ablations, radiotherapy, chemotherapy, hormone-therapy). Approaches to the analyses of the experiences of those patients who were interviewed are cross-sectional, combining the phenomenological approach (the experience lived by these people), the interactionist approach, and the postponed narratives from these surviving patients, as well as those narratives related to the experience of living these forms of cancers. Identity-related tensions, the mourning based on the male identity and the stigma are placed at the heart of the experiences, closely related to the temporary and permanent metamorphoses of the body after the administration or practice of biomedical treatments. Unique experiences are also associated with the influence of the social and cultural construction of this cancerous condition and the male identity in the Western countries
Lanza, Lara de Faria. "Histórias de mulheres sobreviventes ao câncer de mama." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/22/22131/tde-15012013-150720/.
Повний текст джерелаCancers or malignant neoplasias have been reported as important diseases among women, representing causes of death not only in Brazil but in the whole world. Breast cancer is the second most frequent type of cancer worldwide and the first among women. Medical advancements have improved the survival rates for women with breast cancer through more efficient treatments and techniques. Considering the high incidence of breast cancer and the increase of survival rates, the understanding of these women\'s realities - being sick and recovering from it - has become extremely important. The objective of this study was to understand the experiences of surviving breast cancer from elements present in the stories of women survivors. The study is qualitative - 15 surviving breast cancer women were studied and their treatments had been finished 5 years earlier at least. The technique used to collect data was through interviews and the analysis was done based in the studies of Little et al. (2002) and Frank (2012). The data was organised considering 3 main moments: the beginning of the disease (medical diagnosis); the confrontation (treatment); and the end (regaining life). The main objective was to understand the meaning each woman gave to her experience after having survived. Many women have had their identities changed after the disease and most of them have managed to regain their lives. Thus, the results show the singularity and the diversity in experiencing getting sick and surviving and the effects of these experiences in women\'s identities.
Cornish, Leah V. "Adolescent and young adult romantic relationships and cancer: Comparing patient and partner." Ohio University Art and Sciences Honors Theses / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ouashonors1429266467.
Повний текст джерелаHagan, June Renata Louise. "When the life story begins : self-defining memories, identity and the developing self in young adults with experience of cancer." Thesis, University of Leeds, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434167.
Повний текст джерелаForsberg, Lisa, and Niklas Mobäck. "Att vara eller att inte vara - en man : En litteraturöversikt över hur mäns manliga identitet förändras vid prostatacancer." Thesis, Ersta Sköndal högskola, Institutionen för vårdvetenskap, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:esh:diva-3963.
Повний текст джерелаBackground: Prostate cancer is the most common type of cancer for men in the Western world. Nurses’ task is to support men who suffer from prostate cancer and to make sure they understand important information that’s been given, so that these men can make rational decisions concerning their eventual treatment. Further, previous research describes masculinity as a complex concept which can be viewed from different angles and perspectives. Men’s experience of masculinity seems to be an important issue to consider when treating patients with prostate cancer. Aim: To describe how men with prostate cancer experience how the disease and treatment change their body and masculine identity. Methods: The literature review was based on eleven qualitative articles that were examined and analyzed. The articles were gathered from the databases CINAHL with full text, and PubMed Results: The result was thematized into five main categories: The treatment’s impact on men’s experience of masculinity describes how the treatment side effects: impotence, loss of libido and sexual imaginations, and the feminized body, changed how the men experienced their masculinity. The treatment’s impact on men’s ability to urinate examines the treatment’s side effects of incontinence and urination disorders, and how this affected men in their everyday life. Men handling their feelings and changed body examines different strategies for how men handling their new life situation, and the changes of their bodies. Changes in men’s relations and masculinity describes how prostate cancer and treatment changed men’s relationships to woman and other men, and how this affected their experience of masculinity. Discussions: The discussion is proceed by Dahlberg & Segesten’s theory about the “the lived body”. From this point of view the discussion examines how the masculine identity is affected by prostate cancer and its’ treatments. Further, the need to see the man as one individual with unique qualities and experiences is described, which will ease the nurses’ task to provide relevant information, and help the man find strategies to handle the changed life situation.
Tindle, Danielle A. "Creating meaning: the cancer survivorship experiences of young adults in Australia, England and the United States." Thesis, Queensland University of Technology, 2015. https://eprints.qut.edu.au/82216/1/Danielle_Tindle_Thesis.pdf.
Повний текст джерелаBenfatti, Flávia Andréa Rodrigues. "Pornografia e criticidade: as faces de Henry Miller em Tropic of Cancer e Tropic of Capricorn sob o viés autobiográfico." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/8/8147/tde-06112013-105313/.
Повний текст джерелаThis research analyzes the works Tropic of Cancer (1961) amd Tropic of Capricorn (1961) by the American author Henry Miller under the autobiographical perspective. The aim is to investigate in both narratives how the author constructs his narrator\'s masculine identity through his sexual experiences. What we can realize is that the author, as an autobiographical protagonist, sometimes behaves himself within the hegemonic masculinity parameters in relation to the sexual intercourse or in conversations about women with his male partners since he comes from a patriarchal background. On the other hand, the author-narrator is also in favor of liberal attitudes concerning sexuality since his identity and his values are revised and reorganized all through the narrative process. Besides, we also look at other aspects in the narratives which support the narrator\'s identity construction and the author\'s way of writing whose aesthetics breaks the rules of the North-American academicism of the interwar period. The narrator, through his free soul, audaciously criticizes the facts of life involving the two societies described in the book - the American and the French comparing them by denigrating the first and praising the second. In the narratives we also analyse the long reflexcions about sex, love, freedom, marriage, race, ethnics, life, death through commentaries, descriptions and daydreams alternating them by using irony, humor and a lot of metaphors.
Lindkvist, Karin, and Amanda Roynesdotter. "Sjung av hjärtat, sjung! : Musikinterventioners effekter på individer med cancersjukdom." Thesis, Röda Korsets Högskola, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:rkh:diva-2591.
Повний текст джерелаBackground: Cancer is one of the most common diagnoses to affect people all across the globe. The last years more effective treatments have lead to more people surviving or living longer with their cancer diagnosis; which implicates that an increasing number of individuals now and in the future, will be in need of more and better health-promoting interventions. WHO defines health as a state in which absence of disease does not signify good health, but a state which also includes individual physical, mental and social well-being. Aim: The aim of the study was to highlight the effect of musical interventions for patients with diagnosed cancer. Method: A literary study which consists of six quantitative studies, four qualitative studies, and three of mixed methods. Results: The results showed that patients diagnosed with cancer used music as a health-promoting intervention to ease pain, distress and anxiety, as well as a strategy to cope with the diagnosis. The results also showed that musical interventions could function as a way of maintaining the identity the individual had before the disease. Furthermore showed the result that some individuals were not helped by music as a health-promoting intervention. Music in some cases were associated with the diagnoses, causing the participants to feel unease and having the opposite effect to relief and support. Conclusion: Musical intervention, for most individuals with diagnosed cancer, has the ability to give participants access to all different emotions and cope with the disease. Musical intervention is also a health-promoting intervention which is flexible, easily adjustable with the ability to reach many people.
Standifer, Maisha. "The Blurred Lines of HPV and Cervical Cancer Knowledge: Exploring the Social and Cultural Factors of Identity, Gender, and Sexuality in Caribbean Immigrant Women." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6397.
Повний текст джерелаØrtoft, Merethe. "Det sårede selv : Kvalitativt studie om at blive ramt af kræft i æggestokkene." Thesis, Nordic School of Public Health NHV, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:norden:org:diva-3141.
Повний текст джерелаPurpose: The purpose of the study was to obtain an increased understanding of how women with newly diagnosed ovarian cancer are experiencing their own coping and how meaning and identity constructed in the first period after the diagnosis Method: Used a qualitative approach with narrative interviews with six women who have been diagnosed with ovarian cancer within six months. Data analysis used a narrative analysis method "The Holistic Content Perspective" to get an overall picture of the informants' themselves, as it was presented in their stories Result: The study shows three different development paths that must be considered in conjunction with women's age, life period, and the spread of disease. A development path used by younger women who experience the disease as threatening to the identity that they defend themselves by denying the seriousness of the disease and in no way identify with this. They choose to live life the same as before they became ill and the experience of meaningful attempts maintained through denial of the seriousness of the disease. Another path of development emerged in the elderly women who understand the disease as a part of life and quickly begin a providing of meaningful and maintenance of identity, how they relate to disease and its potential consequences such as loss of life. These women learn to live with the disease as part of their identity. A third path of development was found in women where the disease was in an advanced stage and the physical and social suffering becomes dominant. These women struggle to retain or find meaning, instead characterized by meaninglessness, while identity is difficult to maintain, with self image and self-understanding recover from, because they can no longer know themselves Conclusion: The construction of meaning and identity as a part of it to cope with newly discovered cancer of the ovary are important for women, but the processes around how women cope, is different depending on age, life duration and spread of the disease. Health promotion interventions to improve coping processes among these women must keep pace with these different development paths to ensure maximum health.
ISBN 978-91-86739-05-8
Lugton, Jean. "The meaning of social support : a descriptive study of informal networks and of health visitors' formal role in supporting the identity of women with breast cancer." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/20638.
Повний текст джерелаRocha, Magna Celi Mendes da. "O processo de escolarização do aluno mutilado pelo câncer: a transformação da identidade no processo de inclusão escolar." Pontifícia Universidade Católica de São Paulo, 2009. https://tede2.pucsp.br/handle/handle/16590.
Повний текст джерелаCoordenação de Aperfeiçoamento de Pessoal de Nível Superior
This study aimed to understand the formation of the identity of the student mutilated by childhood cancer, with focus on process integration and reintegration school, based on the assumptions of inclusive education. The theoretical perspective that underlies the identity category, in this study was proposed by Antonio da Costa Ciampa that, in the context of Social Psychology, studies the identity as a synthesis of multiple determinations. Identity is understood as a metamorphosis, term that he uses to communicate the idea of continuous movement and transformation as constituents of this process. This is a qualitative research. The subjects of this research were eight survivors of childhood cancer, with apparent physical mutilation, who lived the process of integration or reintegration into regular school, after the end of treatment. Data were collected and organized in two distinct ways: mini-cases and case study. Of the eight subjects of research, we conducted interviews, focused on the process of integration or reintegration into school with seven of them, that we call mini-cases. With the other subject, considered emblematic we did a case study using the narrative of the life history, trying to understand the transformations of his identity in the process of school inclusion. The data show that the experiences of these subjects are varied, and in some cases it can be affirm that there was indeed school inclusion, others that were excluded, either stereotypical attitudes or prejudice, possibly by indifference. In the case of the subject considered as emblematic, it was observed that, in terms of schooling was not inclusion, but a process of integration, however, the subject not suffer exclusion, for him, the inclusion in sporting activities determined the process of overcoming their conditions, towards a metamorphosis emancipatory
A presente pesquisa teve por objetivo compreender a constituição da identidade do aluno mutilado pelo câncer infantil, com foco no processo de inserção e reinserção escolar, com base nos pressupostos da educação inclusiva. A perspectiva teórica que fundamenta a categoria Identidade, nesta pesquisa, foi elaborada por Antônio da Costa Ciampa que, no âmbito da Psicologia Social, estuda a Identidade como síntese de múltiplas determinações. A identidade é entendida como metamorfose, expressão que utiliza para dar a idéia de movimento e contínua transformação como constituintes desse processo. Trata-se de uma pesquisa qualitativa. Os sujeitos desta pesquisa foram oito sobreviventes do câncer infantil, com mutilação física aparente, que viveram seu processo de inserção ou reinserção escolar regular, após o término do tratamento. Os dados foram obtidos e organizados de dois modos distintos: mini-casos e estudo de caso. Dos oito sujeitos da pesquisa, fizemos entrevistas, focadas no processo de inserção ou reinserção escolar com sete deles, o que chamamos de mini-casos. Com o outro sujeito, considerado emblemático, fizemos um estudo de caso, utilizando a narrativa da história de vida, buscando compreender as transformações de sua identidade no processo de inclusão escolar. Os dados demonstram que as experiências desses sujeitos são variadas, havendo casos em que se pode afirmar que houve inclusão escolar de fato; outros em que houve exclusão, seja por atitudes estereotipadas ou de preconceito, seja pela indiferença. No caso do sujeito considerado como emblemático, percebeu-se que, do ponto de vista da escolarização não houve inclusão, mas um processo de integração; entretanto, o sujeito não sofreu exclusão; para ele, a inclusão em atividade esportiva foi o que determinou o processo de superação de suas condições, em direção à metamorfose emancipatória
Feinstein, Carla Fran. "Dying to Know." PDXScholar, 2010. https://pdxscholar.library.pdx.edu/open_access_etds/1318.
Повний текст джерелаHedestig, Oliver. "Att leva med lokaliserad prostatacancer : "oss män emellan"." Doctoral thesis, Umeå universitet, Strålningsvetenskaper, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-898.
Повний текст джерелаGu, Jinghua. "Novel Monte Carlo Approaches to Identify Aberrant Pathways in Cancer." Diss., Virginia Tech, 2013. http://hdl.handle.net/10919/51950.
Повний текст джерелаPh. D.
Fewings, Eleanor Rose. "The use of whole exome sequencing data to identify candidate genes involved in cancer and benign tumour predisposition." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/285963.
Повний текст джерелаRybaczyk, Leszek A. "Comparative Gene Expression Analysis To Identify Common Factors In Multiple Cancers." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1211958921.
Повний текст джерелаKalluru, Vikram Gajanan. "Identify Condition Specific Gene Co-expression Networks." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1338304258.
Повний текст джерелаLaurin, de Castro Judy. "Cancers effekt på sexualitet : en litteraturöversikt för att belysa hur uppfattningen av sexualitet förändras hos personer med cancer - ett förbättringsområde för den palliativa sjuksköterskan." Thesis, Sophiahemmet Högskola, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:shh:diva-2442.
Повний текст джерелаDe, Melo E. Silva Francilene Maria. "Identité, Travail et Genre en psychosomatique : à propos du cancer du sein." Phd thesis, Conservatoire national des arts et metiers - CNAM, 2013. http://tel.archives-ouvertes.fr/tel-00841612.
Повний текст джерелаCarr, Nicole. "Data Pooling to Identify Differentially Expressed Genes in Lung Cancer of Nonsmokers." University of Toledo Health Science Campus / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=mco1461881266.
Повний текст джерелаSoares, Thais Costa Cardoso. "Os movimentos sociocomunicativos de ativistas engajadas na luta contra o câncer de mama no Brasil." Universidade do Vale do Rio dos Sinos, 2016. http://www.repositorio.jesuita.org.br/handle/UNISINOS/5389.
Повний текст джерелаMade available in DSpace on 2016-06-15T13:34:29Z (GMT). No. of bitstreams: 1 Thais Costa Cardoso Soares_.pdf: 2484343 bytes, checksum: 09a2b2961ce3d2ccc7ba625a21bfafaa (MD5) Previous issue date: 2016-04-25
CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
A pesquisa argumenta sobre as possibilidades de construção de vínculos entre sujeitos comunicantes e o exercício da cidadania, possibilitada pelas novas tecnologias de comunicação. Para tal, analisa os processos digitais de comunicação desenvolvidos pela Federação Brasileira de Instituições Filantrópicas de Apoio à Saúde da Mama (FEMAMA) e as interações de ativistas engajadas na luta contra o câncer de mama, nesses espaços. Por meio da pesquisa teórica problematiza a cidadania, como conceito norteador que conduz as práticas de pesquisa e perpassa os processos comunicacionais. Ainda reflete sobre o pertencimento, como categoria central para o efetivo exercício da cidadania. A pesquisa também aborda as lógicas tecnocomunicativas que cercam os ambientes digitais da organização. O percurso de investigação compreende uma reflexão epistemológica sobre os métodos, seguida dos procedimentos de pesquisa documental, bibliográfica, teórica e metodológica. Além disso, a estratégia metodológica trabalha uma combinação da abordagem etnográfica com netnográfica, partindo da análise sistemática dos ambientes digitais da Femama, para a observação de interações presenciais e de entrevistas em profundidade com as ativistas da organização. Os resultados mostram os usos e apropriações que os sujeitos fazem da tecnologia durante suas interações, e verificam que estes espaços comunicacionais têm potencial para o exercício da cidadania comunicativa e para a formação de vínculos identitários. No entanto, constatou-se que para o pleno exercício da cidadania não basta disponibilizar os meios técnicos necessários para interação e participação. É preciso garantir que haja pluralidade de opiniões na forma de planejar e produzir a informação, nos modos de construir os discursos e na maneira de pensar a comunicação como um todo. Além disso, ficou evidente que a perspectiva cidadã precisa fazer parte da própria constituição das organizações, de maneira estrutural, que também se reflita nas práticas cotidianas.
The research argues about the possibilities of bond establishment between individuals and possibilities of exercising, offered by the new technologies of communications. To accomplish it, this research analyzes the digital media developed by The Brazilian Federation of Philanthropic Breast Health Institutions (FEMAMA) and the interactions of the activists engaged on the fight against breast cancer, in these spaces. Trough theoretical research problematize the citizenship, as a guiding concept, which conducts the research practices and goes through communicational processes. It also reflects about the belonging, as a central category to the effective citizenship exercise. The research also address the techno communicative logics in which the organization’s digital spaces are involved. The investigation path concerns an epistemological reflection about methods, followed by the research procedures of documental, bibliographical, theoretical and methodological research. Besides that, the methodological strategy works through a combination of ethnographic and netnografic approaches, starting with the systemic analyses of Femama’s digital spaces, following to present activities observations and interviews with the organization’s activists. The results show the uses and appropriations the individuals do of technology during their interactions, and verifies that those communicational spaces have the potential to the exercise of communicative citizenship and to the formation of identity bonds. Although, it was possible to see that it is not enough to make the technological means to participations and interactions available to guarantee the full citizenship exercise. It is necessary to have diversity of opinions on the information’s planning and producing processes, on the discourse building methods, and on the way of thinking communications as a whole. Besides that, it became clear that the citizen perspective needs to be a part of the own organization constitution, in a structural way, which also reflect itself on daily practices.
Hayward, J. D. "Next generation sequencing approaches to identify novel susceptibility genes for epithelial ovarian cancer." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1457055/.
Повний текст джерелаNoble, Fergus. "Oesophageal Cancer : strategies to improve outcomes, and identify novel immunological biomarkers and targets." Thesis, University of Southampton, 2014. https://eprints.soton.ac.uk/408820/.
Повний текст джерелаHandly, Erika Daphne. "CRISPRi screens to identify combination therapies for the improved treatment of ovarian cancer." Thesis, Massachusetts Institute of Technology, 2020. https://hdl.handle.net/1721.1/130803.
Повний текст джерелаCataloged from the official PDF version of thesis. "February 2021."
Includes bibliographical references (pages 153-168).
Ovarian cancer is the fifth leading cause of cancer death for women in the United States, with only modest improvements in patient survival in the past few decades. Standard-of-care consists of surgical debulking followed by a combination of platinum and taxane agents, but relapse and resistance frequently occur. To identify genes that confer sensitivity or resistance in tumor cells treated with platinum chemotherapeutics, I performed genome-wide screens combining cisplatin or oxaliplatin with CRISPRi pooled gene knockdowns. Screens were analyzed at 9-days to mimic patient care, and at 48-hours to isolate the short-term DNA damage response. Genes whose knockdown caused sensitivity to the platinum chemotherapeutics were identified through a multi-objective optimization approach to account for knockdown efficiencies and variances in sequencing depth.
To filter the noise in the genome-wide screen and more confidently identify 'hits,' a smaller pooled CRISPRi screen of four hundred targets was designed, and a few 'hits' were validated. Interestingly, knockdown of FAAP24, a component of the FA core complex, was found to sensitize multiple ovarian cancer cells to platinum compounds, and thus may be a promising candidate for a combination treatment with oxaliplatin and cisplatin. Chapter 5 details an implementation of a combination therapy with cisplatin using peptide nanoparticles. Peptide nanoparticles are a promising therapeutic for the delivery of siRNA and allow for targeting of specific proteins that are difficult to inhibit with small molecular inhibitors; specifically, nanoplexes allowed for the targeting of the REV3 protein, the catalytic component of the translesion synthesis polymerase.
Interfering with REV3 expression through siRNA has a synergistic effect with cisplatin treatment in both human and mouse models of lung cancer, indicating that REV3 is an excellent target to combine with cisplatin therapies. This REV3 knock-down sensitivity was also extended to human ovarian cancer cell lines, indicating the potential of the combination treatment for both lung and ovarian cancers.
by Erika Daphne Handly.
Ph. D.
Ph.D. Massachusetts Institute of Technology, Department of Biological Engineering
Murabito, Ettore. "Application of differential metabolic control analysis to identify new targets in cancer treatment." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/application-of-differential-metabolic-control-analysis-to-identify-new-targets-in-cancer-treatment(3a9b75ba-027d-449b-af38-263341953418).html.
Повний текст джерелаLooi, Kok Sun. "Using proteomic approach to identify tumor-associated antigens as biomarkers in hepatocellular carcinoma." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2008. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.
Повний текст джерелаO'Neill, John Robert. "Strategies to identify novel therapeutic targets for oesophageal adenocarcinoma." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/10062.
Повний текст джерела