Дисертації з теми "CAM Use and Vaccination"
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Scheppler, Lorenz. "The use of lactic acid bacteria for vaccination /." [S.l.] : [s.n.], 2004. http://www.zb.unibe.ch/download/eldiss/04scheppler_l.pdf.
Повний текст джерелаAlmustafa, Nawaf Mohammed. "The use of CAD CAM for fixed partial prostheses." Thesis, University of Dundee, 2016. https://discovery.dundee.ac.uk/en/studentTheses/7185f4c0-4f47-4072-8b0a-7ae09c1e8c01.
Повний текст джерелаLehane, K. J. "Computer aids for variant design." Thesis, University of Bristol, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292453.
Повний текст джерелаCosma, Antonio. "Use of the regulatory protein Nef for vaccination against HIV-1." Diss., kostenfrei, 2008. http://edoc.ub.uni-muenchen.de/8329/.
Повний текст джерелаShrestha, Priyanka. "Predicting Quantity of Complementary and Alternative Medicine Use." Miami University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=miami1500381639467327.
Повний текст джерелаPower, Carl A. "Immunology of BCG vaccination in mice, implications for tuberculosis vaccination and for the use of BCG as a recombinant vaccine vector." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0031/NQ63963.pdf.
Повний текст джерелаWinch, Graham. "The implementation of CAD/CAM systems in the metalworking industries." Thesis, University of Warwick, 1992. http://wrap.warwick.ac.uk/3718/.
Повний текст джерелаHanson, Diamond Diane. "Use of HPV Vaccination for Cervical Cancer Prevention in African American Women." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/5344.
Повний текст джерелаBell, Stephen Graham. "The use of active site mutants of cytochrome P450(cam) in chemical synthesis." Thesis, University of Oxford, 1999. http://ora.ox.ac.uk/objects/uuid:7f48cf79-37b0-45cd-a40e-e971af466cff.
Повний текст джерелаGalbraith, N. "Cognition associated with use of, and belief in, complementary and alternative medicine (CAM)." Thesis, University of the West of England, Bristol, 2018. http://eprints.uwe.ac.uk/32371/.
Повний текст джерелаMartínez, Flórez Alba. "Drug repurposing of bioenergetic modulators: use in treatment and vaccination of protozoan parasitic diseases." Doctoral thesis, Universitat Autònoma de Barcelona, 2017. http://hdl.handle.net/10803/458381.
Повний текст джерелаLeishmaniases, African and American trypanosomiases and malaria are parasitic diseases that constitute a major global health problem. The increasing number of drug‐resistances to their current treatments, toxicity cases and the health assistance often required for their administration, makes it urgently necessary to develop efficient vaccines for humans and new affordable therapies, easy to apply and resistant to harsh storage conditions. Due to the fact that these diseases share similar metabolic requirements with better studied diseases, we chose drug repurposing as a potentially effective approach against them. With this purpose, six different compounds used in anti‐cancer research —dichloroacetate (DCA), 3‐bromopyruvate (3BP), 2‐deoxy‐D‐glucose (2DG), lonidamine (LND), metformin (MET), and sirolimus (SIR)— were selected according to their ability to modulate energy production and proliferation related metabolic pathways. The aim of this study was to validate the suitability of these bioenergetics modulators for the management of visceral leishmaniasis, malaria and African and American trypanosomiasis as a treatment, or as a preventive tool by enhancing the protective power of a vaccine against L. infantum. The effectiveness of these compounds was first evaluated on in vitro models of each parasite ― Chagas disease (Trypanosoma cruzi), human African trypanosomiasis (Trypanosoma brucei), visceral leishmaniasis (Leishmania infantum) and malaria (Plasmodium falciparum)―. L. infantum promastigotes were not susceptible to these compounds, whereas L. infantum intracellular amastigote growth was dose‐dependently reduced by 3BP (IC50 = 17.19 μM) and DCA (IC50 = 631.5 μM). In the T. brucei in vitro model all the tested compounds, with the exception of 2DG, affected parasite survival with IC50 values of 1.24 mM for DCA, 76.57 μM for 3BP, 26.76 μM for LND, 2.14 μM for SIR, and 17.30 mM for MET. In the case of T. cruzi, DCA, 3BP, 2DG, LND, and MET showed parasite‐killing activity with IC50 values of 27.07 mM, 27.63 μM, 7.27 mM, 78.37 μM, and 18.48 mM, respectively. For P. falciparum DCA (IC50 = 5.39 mM), 2DG (IC50 = 4.19 mM), LND (IC50 = 209.13 μM), MET (IC50 = 1.32 mM), and SIR (IC50 = 2.50 μM), showed antiplasmodial activity. These results reinforce the hypothesis that drugs with proven efficacy in the treatment of cancer by interfering with energy production might be useful in treating threatening parasitic diseases and provide new opportunities for their repurposing. However, when compounds that were effective in the in vitro approach were administered to the in vivo rodent models of these diseases, none of them contributed to disease management or parasite load control. Immunological analysis in the VL hamster model revealed a significant downregulation of immune‐activation in infected animals treated with DCA and 3BP, which may also contribute to treatment failure. In the last chapter of this work, the suitability of sirolimus as an immunomodulatory compound to boost the activity of a preventive vaccine against VL was analyzed. Sirolimus is an already marketed compound that has been described to boost immune protection against different disease models. In our study, Syrian hamsters were treated with sirolimus concomitantly with the administration of a plasmid DNA vaccine carrying the Leishmania genes LACK, TRYP, PAPLE22 and KMPII, and the subsequent response towards a L. infantum challenge was studied. Our results show that the DNA vaccine itself efficiently reduced the burden of parasites in skin (P = 0.0004) and lymph nodes (P = 0.0452), which was potentiated by SIR administration by also inducing parasitological protection in the spleen (P = 0.0004). The study of immune markers in spleen suggests that lower production of IFN‐γ and the concurrent increase of FoxP3+ expression may be responsible for the protection mediated by the DNA vaccine that was potentiated by sirolimus.
Jain, A. "Use of electronic health records to investigate vaccination inequalities in older individuals in England." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2018. http://researchonline.lshtm.ac.uk/4650293/.
Повний текст джерелаKumar, Ashwin. "The use of complementary and alternative medicine (CAM) as lived by individuals living with chronic illnesses." View thesis, 2007. http://handle.uws.edu.au:8081/1959.7/39660.
Повний текст джерелаA thesis presented to the University of Western Sydney, College of Health and Science, School of Nursing, in fulfilment of the requirements for the degree of Doctor of Philosophy. Includes bibliographies.
Burt, T. H. "Factors influencing the successful production of large plasmids for use in gene therapy and DNA vaccination." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1444360/.
Повний текст джерелаElAswad, Bahaa El-Deen Wadea Ramadan. "Use of Schistosoma mansoni calreticulin, a highly immunogenic parasite antigen, in diagnosis of and vaccination against schistosomiasis." Thesis, University of Leicester, 2010. http://hdl.handle.net/2381/9961.
Повний текст джерелаLemaire, Edward D. "Development and validation of a quantitative method for defining manual prosthetic modifications for use with CAD/CAM systems." Thesis, University of Strathclyde, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342455.
Повний текст джерелаAwortwe, Charles. "Pharmacokinetic herb-drug interaction study of selected traditional medicines used as complementary and alternative medicine (CAM) for HIV/AIDS." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/96796.
Повний текст джерелаENGLISH ABSTRACT: Introduction The increasing intake of traditional medicines among HIV/AIDS patients in sub-Saharan Africa needs urgent consideration by clinicians and other healthcare providers since the safety of such medications are unknown. The pharmacokinetic parameters - Absorption, Distribution, Metabolism and Elimination (ADME) play important role in the safety evaluation of drugs, thus implicating drug metabolizing enzymes and transporters as critical indicators for herb-drug interactions. The objective of this study was to evaluate the risk potential of seven herbal medicines commonly consumed by HIV/AIDS patients for drug interactions applying in vitro models. In this study, inhibition and induction effects of the herbal medicines on cytochrome P450s (CYPs) 1A2, 2C9, 2C19, 2D6 and 3A4 as well as P-glycoprotein (P-gp) were investigated. Methods Herbal medicines – Lessertia frutescens, Hypoxis hemerocallidea, Kalanchoe integra and Taraxacum officinale were sourced from Medico Herbs, South Africa were identified by experts from Compton Herbarium, South African National Biodiversity Institute, Cape Town. Moringa oleifera, Echinacea purpurea and Kalanchoe crenata were obtained from the repository of the National Centre for Natural Product Research (NCNPR), University of Mississippi, USA. Reversible inhibitory effect of aqueous and methanol herbal extracts were evaluated in recombinant CYPs applying the fluorescent metabolites at specified excitation/emission wavelengths; CYP1A2 (3-cyano-7-hydroxycoumarin (CHC); 405/460 nm), CYP2C9, CYP2C19 and CYP3A4 (7-hydroxy-4-(trifluoromethyl)-coumarin (HFC); 405/535 nm) and CYP2D6 (7-hydroxy-4-(aminomethyl)-coumarin (HAMC); 390/460 nm). Comparative studies in human liver microsomes (HLM) and recombinant CYPs were conducted to investigate the inhibitory effect of methanol herbal extracts and fractions on 6β testosterone hydroxylation activity. Time dependent inhibitory (TDI) effect of the herbal extracts were evaluated applying the IC50 shift fold, normalized ratio and the NADPH-, time- and concentration-dependent approaches. Influence of herbal extracts on metabolic clearance of testosterone was assessed in both HLM and human hepatocytes. The effects of each herbal extract on expression of CYP1A2, CYP3A4 and MDR1 genes were evaluated in activated human pregnane X receptor (PXR) co-transfected HepG2 cells. Finally, the inhibitory effect of herbal extracts on P-gp was assessed using the calcein-acetoxymethyl ester (calcein-AM) uptake and the digoxin radiolabelled substrates in MDCKII-MDRI cells. Results The aqueous extracts of Moringa oleifera, Kalanchoe integra, Kalanchoe crenata, Echinacea purpurea and Lessertia frutescens demonstrated high risk of in vivo inhibition on CYPs 3A4 and 1A2 with Cmax/Ki >1.0. Methanol extracts of these herbal medicines also indicated potential risk of reversible drug interaction. The methanol extracts of M. oleifera, K. crenata and L. frutescens showed strong TDI effect on CYP3A4 with IC50 shift fold >1.5 and normalised ratio <0.7. Moringa oleifera intermediately reduced intrinsic clearance of testosterone in human hepatocytes (2 ≤ AUC ratio ≤ 5) when scaled up to humans. Methanol extracts of Echinacea purpurea up-regulated the expression of CYP1A2, CYP3A4 and MDR1 genes in activated PXR. Kalanchoe crenata and Echinacea purpurea indicated strong inhibition on P-gp by reducing transport of digoxin across hMDR1-MDCKII cell monolayer from basolateral to apical with IC50 values of 18.24 ± 2.52 μg/mL and 24.47 ± 4.97 μg/mL, respectively. Conclusion The herbal medicines especially M. oleifera, K. integra and E. purpurea have the potential to cause herb-drug interaction in vivo if sufficient hepatic concentration is achieved in humans.
AFRIKAANSE OPSOMMING: Inleiding Die verhoogde inname van tradisionele medisynes onder MIV/VIGS-pasiënte in sub-Sahara-Afrika verg dringend oorweging deur klinici en ander gesondheidsorgverskaffers, aangesien die veiligheid van sodanige medikasies onbekend is. Die farmakokinetiese parameters – Absorpsie, Distribusie, Metabolisme en Eliminasie (ADME) – speel ’n belangrike rol by die veiligheidsevaluering van geneesmiddels, en impliseer gevolglik geneesmiddel-metaboliserende ensieme en vervoerders as kritiese indikators vir krui-geneesmiddel-interaksies (HDI). Die oogmerk van hierdie studie is om die risikopotensiaal van sewe kruiemedisynes wat algemeen deur MIV/VIGS-pasiënte geneem word, vir geneesmiddel-interaksies te evalueer deur in vitro-modelle te gebruik. In hierdie studie is die inhiberings- en induseringsuitwerkings van die kruiemedisynes op sitochroom P450’s (verkort na CYP’s) 1A2, 2C9, 2C19, 2D6 en 3A4, sowel as P-glikoproteïen (P-gp), ondersoek. Metodes Kruiemedisynes – Lessertia frutescens, Hypoxis hemerocallidea, Kalanchoe integra en Taraxacum officinale – is van Medico Herbs, Suid-Afrika, bekom en deur kundiges van die Compton-herbarium, by die Suid-Afrikaanse Nasionale Biodiversiteitsinstituut, Kaapstad, geïdentifiseer. Moringa oleifera, Echinacea purpurea en Kalanchoe crenata is van die bewaarplek van die Nasionale Sentrum vir Natuurlike Produknavorsing (NCNPR) aan die Universiteit van Mississippi in die VSA verkry. Die omkeerbare inhiberende uitwerking van kruie-ekstrakte in water en metanol is in rekombinante CYP’s geëvalueer deur die gebruik van die fluoresserende metaboliete op gespesifiseerde opwekkings-/emissiegolflengtes; CYP1A2 (3-siaan-7-hidroksikumarien (CHC); 405/460 nm), CYP2C9, CYP2C19 en CYP3A4 (7-hidroksi-4-(trifluoormetiel)-kumarien (HFC); 405/535 nm) en CYP2D6 (7-hidroksi-4-(aminometiel)-kumarien (HAMC); 390/460 nm). Vergelykende studies van menslikelewermikrosome (HLM) en rekombinante CYP’s is uitgevoer om die inhiberende uitwerking van metanolkruie-ekstrakte en -fraksies op 6β-testosteroonhidroksileringsaktiwiteit te ondersoek. Die tydafhanklike inhiberende uitwerking (TDI) van die kruie-ekstrakte is geëvalueer deur gebruikmaking van die IC50-verskuiwingsvou-, die genormaliseerdeverhoudings- en die NADPH-, tyd- en konsentrasieafhanklike benaderings. Die invloed van kruie-ekstrakte op metaboliese testosteroonverheldering is in beide HLM en menslike hepatosiete geëvalueer. Die uitwerkings van elke kruie-ekstrak op die uitdrukking van CYP1A2-, CYP3A4- en MDR1-gene is in geaktiveerde menslike pregnaan-X-reseptor(PXR)-, ko-getransfekteerde HepG2-selle geëvalueer. Laastens is die inhiberende uitwerking van kruie-ekstrakte op P-gp geëvalueer, met gebruikmaking van die kalsien-asetoksimetiel-ester (kalsien-AM)-opname en die digoksien- radiogemerkte substrate in MDCKII-MDRI-selle. Resultate Die ekstrakte in water van M. oleifera, K. integra, K. crenata, E. purpurea en L. frutescens het ’n hoë risiko van in vivo-inhibering op CYP’s 3A4 en 1A2 met Cmaks/Ki >1.0 getoon. Ekstrakte van hierdie kruiemedisynes in metanol het verder potensiële risiko van omkeerbare geneesmiddelinteraksie getoon. Die ekstrakte van M. oleifera, K. crenata en L. frutescens in metanol het sterk TDI-uitwerking op CYP3A4 met IC50-verskuiwingsvou >1.5 en genormaliseerde verhouding <0.7 getoon. M. oleifera het intermediêre vermindering van intrinsieke testosteroonverheldering in menslike hepatosiete (2 ≤ AUC verhouding ≤ 5) tot gevolg wanneer die skaal na mense verhoog word. Ekstrakte van E. purpurea in metanol het die uitdrukking van CYP1A2-, CYP3A4- en MDR1-gene in geaktiveerde PXR opgereguleer. K. crenata en E. purpurea het sterk inhibering van P-gp getoon deur die vervoer van digoksien deur die hMDR1-MDCKII-selmonolaag van basolateraal tot apikaal met IC50-waardes van onderskeidelik 18.24 ± 2.52 μg/mL en 24.47 ± 4.97 μg/mL te verminder. Gevolgtrekking Kruiemedisynes, veral M. oleifera, K. integra en E. purpurea, het die potensiaal om HDI in vivo te veroorsaak indien voldoende hepatiese konsentrasie by mense bereik word.
Gottvall, Maria. "Introduction of School-Based HPV Vaccination in Sweden : Knowledge and Attitudes among Youth, Parents, and Staff." Doctoral thesis, Uppsala universitet, Vårdvetenskap, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-212886.
Повний текст джерелаWang, Shou-Yu (Cindy). "Taiwanese people with cancer and non Western medicine (NWM) use : a grounded theory study." Thesis, Queensland University of Technology, 2007. https://eprints.qut.edu.au/16473/1/Shou-Yu_Wang_Thesis.pdf.
Повний текст джерелаWang, Shou-Yu (Cindy). "Taiwanese people with cancer and non Western medicine (NWM) use : a grounded theory study." Queensland University of Technology, 2007. http://eprints.qut.edu.au/16473/.
Повний текст джерелаJizi, Lama. "Prevalence and Predictors of Complementary and Alternative Medicine Use among Lebanese College students." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2359.
Повний текст джерелаSchneider, Germar, Sophia Keil, and Gerhard Luhn. "Opportunities, Challenges and Use Cases of Digitization within the Semiconductor Industry." Institute of Electrical and Electronics Engineers (IEEE), 2018. https://tud.qucosa.de/id/qucosa%3A35387.
Повний текст джерелаLorbach, Joshua. "Gaps in Human Immunity Against Swine Origin Influenza A Viruses and the Use of Swine Vaccination to Reduce Public Health Threat." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1587727549815743.
Повний текст джерелаPirri, Carlo. "Complementary and alternative medicine (CAM) in cancer: An evidence-based systematic review of the efficacy and safety of CAMs, and the perceived vs real benefits of CAM use for the quality of life and psychological adjustment of cancer patients undergoing cytotoxic treatment." Thesis, Pirri, Carlo (2014) Complementary and alternative medicine (CAM) in cancer: An evidence-based systematic review of the efficacy and safety of CAMs, and the perceived vs real benefits of CAM use for the quality of life and psychological adjustment of cancer patients undergoing cytotoxic treatment. PhD thesis, Murdoch University, 2014. https://researchrepository.murdoch.edu.au/id/eprint/29185/.
Повний текст джерелаWilliman, Jonathan A., та n/a. "The use of the cytokines IFNγ, IL-12 and IL-23 to modulate immune responses raised by the gene gun method of DNA vaccination". University of Otago. Department of Microbiology & Immunology, 2007. http://adt.otago.ac.nz./public/adt-NZDU20070405.151123.
Повний текст джерелаMehta, Purvi. "Designing and evaluating a health belief model based intervention to increase intent of HPV vaccination among college men: Use of qualitative and quantitative methodology." University of Cincinnati / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1368014093.
Повний текст джерелаKodituwakku, Aruna Poojitha. "Antigen specific B cells in the immune response to Haemophilus influenzae type b PRP conjugate vaccine /." Title page, table of contents and summary only, 2004. http://web4.library.adelaide.edu.au/theses/09PH/09phk769.pdf.
Повний текст джерелаJones, Ellen Hung. "Exploring the use of complementary and alternative medicine in Australian adult patients undergoing anti-cancer treatment." Thesis, Queensland University of Technology, 2022. https://eprints.qut.edu.au/232655/1/Ellen%20Hung_Jones_Thesis.pdf.
Повний текст джерелаLockwood, Lauren. "Introduction of pneumococcal conjugate vaccination in Ethiopia: a cross-sectional analysis of predictors of vaccine use in children aged 12-23 months using Demographic and Health Survey data from 2016." Thesis, Uppsala universitet, Internationell mödra- och barnhälsovård (IMCH), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-352902.
Повний текст джерелаBchir, Lahsen. "Etude theorique et experimentale d'un moteur eolien darrieus : application a l'entrainement de pompes solenoides dans diverses configurations." Paris 6, 1988. http://www.theses.fr/1988PA066046.
Повний текст джерелаShanaube, Kwame, James Hargreaves, Katherine Fielding, Ab Schaap, Katherine-Anne Lawrence, Bernadette Hensen, Charalambos Sismanidis, et al. "Risk factors associated with positive quantiFERON-TB gold in-tube and tuberculin skin tests results in Zambia and South Africa." Public Library of Science (PLOS), 2011. http://hdl.handle.net/10019.1/11596.
Повний текст джерелаIntroduction: The utility of T-cell based interferon-gamma release assays for the diagnosis of latent tuberculosis infection remains unclear in settings with a high burden of tuberculosis. Objectives: To determine risk factors associated with positive QuantiFERON-TB Gold In-Tube (QFT-GIT) and tuberculin skin test (TST) results and the level of agreement between the tests; to explore the hypotheses that positivity in QFT-GIT is more related to recent infection and less affected by HIV than the TST. Methods: Adult household contacts of tuberculosis patients were invited to participate in a cross-sectional study across 24 communities in Zambia and South Africa. HIV, QFT-GIT and TST tests were done. A questionnaire was used to assess risk factors. Results: A total of 2,220 contacts were seen. 1,803 individuals had interpretable results for both tests, 1,147 (63.6%) were QFT-GIT positive while 725 (40.2%) were TST positive. Agreement between the tests was low (kappa = 0.24). QFT-GIT and TST results were associated with increasing age (adjusted OR [aOR] for each 10 year increase for QFT-GIT 1.15; 95% CI: 1.06-1.25, and for TST aOR: 1.10; 95% CI 1.01-1.20). HIV positivity was less common among those with positive results on QFT-GIT (aOR: 0.51; 95% CI: 0.39-0.67) and TST (aOR: 0.61; 95% CI: 0.46-0.82). Smear positivity of the index case was associated with QFT-GIT (aOR: 1.25; 95% CI: 0.90-1.74) and TST (aOR: 1.39; 95% CI: 0.98-1.98) results. We found little evidence in our data to support our hypotheses. Conclusion: QFT-GIT may not be more sensitive than the TST to detect risk factors associated with tuberculous infection. We found little evidence to support the hypotheses that positivity in QFT-GIT is more related to recent infection and less affected by HIV than the TST. © 2011 Shanaube et al.
Publishers' Version
Kuzmick, Emily R. "Investigating the Viability of Agave americana as a Potential Bioenergy Feedstock and its Relative Impact on Surrounding Wildlife." Ohio University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1430829519.
Повний текст джерелаJones, Alexander M. "Fuel Yield Potential of Field Grown Agave americana L. Based on Water Soluble Carbohydrates, Acid Extractable Carbohydrates, and Enzymatic Digestibility Compared to Other Advanced Biofuel Feedstocks." Ohio University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1501173804378294.
Повний текст джерела(9783923), Gabrielle Bryden. "An exploration of unorthodox worldviews that predict vaccine scepticism and use of complementary and alternative medicine." Thesis, 2021. https://figshare.com/articles/thesis/An_exploration_of_unorthodox_worldviews_that_predict_vaccine_scepticism_and_use_of_complementary_and_alternative_medicine/19750360.
Повний текст джерелаPartyka, Elzbieta. "Canadian social workers and complementary and alternative therapies: a web based survey of their knowledge, use and attitudes." 2014. http://hdl.handle.net/1993/23242.
Повний текст джерелаGallardo, L. Antonio J. "Skill and organizational complementarities to CAD/CAM technology use in small and medium sized manufacturing firms /." Diss., 2003. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3117148.
Повний текст джерелаSchutz, Pamela Lorne. "Trends and patterns of use of CAM (Complementary and alternative medicine) among senior nursing students." Thesis, 2006. http://hdl.handle.net/10539/1873.
Повний текст джерелаThe use and teaching of CAM (complementary and alternative medicine) therapies is a growing trend worldwide in the pursuit of health and the amelioration of some disease problems. Chronic, insoluble problems, stress (both mental and physiological), and pain are particularly the target of these therapies. In February 2001, South Africa became a world leader when she passed legislation promoting ten traditional or complementary and alternative therapies into professionalism. The purpose of this study was to assess the trends and patterns of use of senior nursing students of CAM therapies, and their intention to use such CAM therapies on their patients, or to refer their patients to practitioners of CAM therapies. A self-report survey was used to obtain this data, partly constructed from knowledge gathered in the literature review. Senior nursing students from three teaching institutions in Johannesburg participated in the survey. A pilot study to test the feasibility of the study and the reliability of the instrument was carried out at one of these three institutions. The group that participated in the pilot was not the same group that was later used as subjects at this institution. The pilot test was then subjected to a Peason's Product-Moment Correlation test to assess testretest reliability. Pearson's r was found to be 0.8, which shows high reliability of the instrument. Descriptive statistics (frequencies, means, and proportions) were used to summarize and present the results. The main results are as follows. A much larger group of respondents saw allopathic practitioners than CAM practitioners for their personal health problems and to maintain their health. Knowledge of CAM therapies was reported to be fairly low, though this may be due to the number of therapies presented for consideration. A large percentage of the respondents was interested in learning about, and even practicing CAM therapies on their patients, and in referring their patients to CAM practitioners or being able to advise them about CAM therapies and remedies appropriately. Given these results, with regard to nursing education, it was suggested that at least an introductory course to the basic tenets of CAM therapies and "holistic" or "body-mind medicine", needs to be presented to all student nurses. The problems inherent in developing adequate and relevant research avenues for these complex subjects, and an understanding of a range of the most commonly practiced CAM therapies needs to be included at neophyte nursing level. Focussed suggestions are made in the body of the report. Focussed suggestions are also made with regard to future research, both within the field of nursing and related allopathic disciplines possibly interested in incorporating aspects of CAM therapies within their own bodies of knowledge, and outside these disciplines. Suggestions relevant to the teaching and practice of a few CAM therapies practiced by the researcher, and of pharmacological and other possible avenues of research relevant to some of these therapies, will be made in the form of further articles submitted to the professional magazines of the CAM therapies concerned.
Cosma, Antonio [Verfasser]. "Use of the regulatory protein Nef for vaccination against HIV-1 / vorgelegt von Antonio Cosma." 2008. http://d-nb.info/988921219/34.
Повний текст джерелаKumar, Ashwin, University of Western Sydney, College of Health and Science, and School of Nursing. "The use of complementary and alternative medicine (CAM) as lived by individuals living with chronic illnesses." 2007. http://handle.uws.edu.au:8081/1959.7/39660.
Повний текст джерелаDoctor of Philosophy (PhD)
Lu, Jui-Hua, and 盧瑞華. "The Qualitative and Quantitative Study of CAM use and Quality of Life of Cancer Patients in Taiwan." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/89657902205402183848.
Повний текст джерела國立臺北護理健康大學
護理研究所
100
This study was aim to explore the experiences of complementary and alternative medicine (CAM) use as well as to examine the relationships between CAM use, CAM belief, illness perceptions, depression, and quality of life in cancer patients in northern Taiwan. The conceptual model for the study is derived from the the Leventhal's self-regulation model. A three-phase design combining both qualitative and quantitative research were conducted. Specificcally, the three-phase design was as followings:(1) phase 1: exploring the experiences of CAM use;(2) phase 2:developing Chinese version of the complementary and alternative medicine beliefs inventory (CAMBI-Chinese version);(3) phase 3: examining the association between CAM use and quality of life. The study protocol was approved by the institutional review board of the National Taipei University of Nursing and Health science. In the phase 1, the experiences of CAM use from cancer patients was obtained using qualitative research. Participants were recruited form the northern Taiwan using snowball sampling in 2011. Data were collected by in-depth, tape-recorded face-to-face interviews and analyzed using content analysis techniques. Five themes emerged including facing the challenge of cancer; the pressure from the CAM use;life style alternation were the cause of cancer; health were the balance among physical,mind and spiritual; and the concerns regarding CAM use. During the phae 2, the translation as well as the reliability and validity of the the CAMBI-Chinese version (CAMBI-C) were established. At first, the permission from Dr.Bishop was obtained. The translation process were performed using Brislin’s (1986)six setpes and both translation from English to Chinese and back translation were completed. Participants were recruited from the internet from July 1 to July 31 in 2011. A total of two-hundred and sixty-one adults were enrolled in this study. Internal reliability coefficients for the subscales ranged from 0.71 to 0.86, and the overall reliability was 0.85. The test-retest realibity was 0.88. The CAMBI-C had a good content validity among five experts (CVI=1.0). The underlying factor structure of the CAMBI-C comprised belief of natural remedy, belief of participating, and belief of holistic health. Thishree- factor structure explained 52.92% of variance with the KMO of 0.802, value of Bartlett's Test of Sphericity χ 2 being 1695.368(df=136, p<.000). The CAMBI-C scale and subscales were observed to be sensitive to differentiate the CAM user and nonuser (p=.001). The relationship between CAM use and related variables was examined in phase 3 using quantitative study. Participants were recruited form the northern Taiwan using snowball sampling form Aug. 01, 2011 to March 31, 2012. A total of two hundred cancer patients were recruited in this study. Majority of the subjects were female (56.5%) with average age of 53.97 years (SD=12.02). Over half participants were graduated from high school (62.5%), had some religion (75%), current employed (55.5%), married (67.5%) and house hold income between 30,000-10,000 NT$/per month (61.5%). Most Patients were diagnosed of breast cancer (35%), follow by colorectal cancer (18%), and liver cancer (11.5%). Majority of patients were in their cancer stage of II or III (63.5%). The average length since confirmed diagnosed with cancer were 40.14 months (SD=46). Ninty-two percents of the study participants had received surgery for treatment of their cancer, and about 32.5% of them also combined with Chemotherapies. The average number of CAM used in the past 12 months was 2.78 (SD=1.70), including natural products (71.5%), diet supplement (44.5%) and herbs (33.5%). Most of the CAM remedics related informations were obtained from families,relatives or friends. Many of those CAM used by patients at no extra cost. However, the naturals products cost around 1,000-3,000 NT $/per month.The CAM belief was positive among majority of patients. The mean CAMBI-C socre was 80.96 (SD=9.08), 25.08(SD=4.58) for Natural Treatments, 25.22(SD=3.33) for participants in treatment and 30.66 (SD=4.09) for Holistic Health.The mean score of HADS-D was 7.21 (SD=3.41). Total 109 patients (51%) of the study patients sufferred from depression, among those patients, 34.5% had minor depression 14.5% had moderate depression and 2% had severe degree depression. The illness representation of cancer indicated the highest score in consequence (6.78, SD=2.43), emotional representation (6.59, SD=2.45) and the timeline (6.36,SD=2.76). For the causes of cancer, patients mainly attributed to food of diet habit,stress, personal behaviors, gene or overworking. Quality of lifewere measured by FACT-G with total mean socre of 62.25(SD=21.21), indicating a moderate level of QOL.Results showed that cancer patients with younger age, education of high school and higher, married, and higher income were more likely to use CAM. In addition, the more advanced of the cancer, recently diagnosed cancer, and have been received chemotherapy were tend to used CAM (p<.05). Correlational results indicated that CAM belief was negative related to illness perceptions (p<.01). CAM belief was also negative related to depression (p<.01). Depression and illness perceptions were negative related to QOL and four components of QOL (p<.01). About 70% of the variance in QOL can be explained by by depression and illness perceptions. The Sobel test showed that illness perceptions had 30.85% effect (mediate) on the relationship of depression and QOL. The study result can provide basic understaning of cancer patient’s experience of CAM used. This study also developed a reliable and validity tool for measure the belief toward CAM which can be further use in relevance issue. The results also provide vital informations for nurses taking care of cancer patients regarding the issues of CAM use.
Friesen, Elizabeth Louise. "The relationship between complementary and alternative medicine (CAM) use and quality of life among individuals with chronic pain: results from a nationally representative sample." 2014. http://hdl.handle.net/1993/23423.
Повний текст джерелаGibson, Phylliscia. "A Research Framework for Evaluation of RSV Vaccination Use and RSV Outcomes Among Premature Infants Under One Year of Age." 2016. http://scholarworks.gsu.edu/iph_theses/472.
Повний текст джерелаKodituwakku, Aruna Poojitha. "Antigen specific B cells in the immune response to Haemophilus influenzae type b PRP conjugate vaccine / Aruna P. Kodituwakku." Thesis, 2004. http://hdl.handle.net/2440/22085.
Повний текст джерелаKlafke, Nadja. "Interpersonal factors impacting the decision to (continue to) use complementary and alternative medicine (CAM) in men with cancer: a mixed-methods study." Thesis, 2014. http://hdl.handle.net/2440/97249.
Повний текст джерелаThesis (Ph.D.) -- University of Adelaide, School of Psychology, 2014
Cobb, Hugh. "A COST - COMPARISON OF THE USE OF INFLUENZA VACCINE IN OLD AGE HOME RESIDENTS IN JOHANNESBURG." Thesis, 2006. http://hdl.handle.net/10539/1882.
Повний текст джерелаResidents of old age homes are at increased risk for the complications of influenza. Studies in developed countries have consistently shown that influenza vaccination of old age home residents and staff can significantly decrease morbidity and mortality rates and that influenza vaccination is one of the most cost effective interventions possible in this population. No studies have been done on the cost benefit of using influenza vaccine in old age home residents in South Africa. The aim of this study was to evaluate the costs of treating influenza and influenza-like illnesses in old age home residents, and to compare the costs in people who had received the influenza vaccine to those who had not. The study population comprised 151 people residing in two old age homes in Johannesburg, namely Sandringham Gardens and Nazareth House. The study population was divided into two groups- those who received influenza vaccine and those who had not been vaccinated. The residents of Nazareth House who gave consent had all been vaccinated. The subjects at Sandringham Gardens were sub- divided into two groups, namely: “Residents” and “Frail care / wards” section. The general health of the “Frail care” people was poorer than that of the “residents”. Medical records were reviewed, and details of the number of doctor consultations, medication and physiotherapy prescribed, special investigations performed and hospital referrals related to influenza and influenza-like infections were recorded. The costs were then calculated using “medical aid rates”. There were no significant differences in the treatment costs, comparing those who had been vaccinated to those who had not been vaccinated. There are a number of possible explanations for this. These include, most importantly, a low to moderate epidemic activity of influenza in the season that the study was conducted. Other explanations are low patient numbers, the use of symptoms for diagnosis and the use of over the counter therapy. Despite the findings in the present study, the international literature supports the view that influenza vaccination is a cost-effective intervention in the older adult population, particularly those at higher risk. These findings have been implemented in the official guidelines of many countries, including the South African Adult Influenza Vaccination Guideline.
Woodard, Kedra. "Association of Glucosamine and/or Chondroitin Use with Reports of Improved Health and Joint Pain among Individuals with Arthritis, National Health Interview Survey (NHIS) 2012." 2015. http://scholarworks.gsu.edu/iph_theses/415.
Повний текст джерелаYeo, Christe Lai Leng. "Improving patient provider communication through integrating a health information technology system for primary and secondary cervical cancer prevention through use of the human Papillomavirus vaccine of adolescent and cervical cancer screening referral of adult female caregiver." Thesis, 2019. https://hdl.handle.net/2144/36701.
Повний текст джерела2021-06-17T00:00:00Z
Perozo-Marin, Francisco Antonio. "Investigations on avian adeno-associated virus based protein expression for poultry vaccination, the VG/GA strain of Newcastle disease virus (NDV) and the use of FTA cards for NDV detection." 2008. http://purl.galileo.usg.edu/uga%5Fetd/perozo%5Ffrancisco%5Fa%5F200805%5Fphd.
Повний текст джерелаOndrášiková, Michaela. "Zdravý životní styl zájemců o zdravou výživu." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-356304.
Повний текст джерела