Дисертації з теми "Bone point"
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Mountain, Rebecca Vivienne. "Social Stress and Bone Loss at Point of Pines Pueblo, Arizona: A pQCT Study on Archaeological Bone." Thesis, The University of Arizona, 2013. http://hdl.handle.net/10150/311471.
Повний текст джерелаArnold, Patricia A. "Validation of Mechanical Response Tissue Analysis by Three-Point Mechanical Bending of Artificial Human Ulnas." Ohio University Honors Tutorial College / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ouhonors1366983271.
Повний текст джерелаRoche, Bernard. "Mise au point de l’évaluation structurelle et fonctionnelle de la vascularisation d’un os long chez la souris : validation dans des modèles de perte osseuse." Thesis, Saint-Etienne, 2013. http://www.theses.fr/2013STET020T.
Повний текст джерелаVascularisation plays a major role in bone biology. Genetically modified mice became the most favorite model in this research field; however, the tools allowing bone vessel analysis on both structural (capillary network) and functional aspects (perfusion) in this animal model remain unsatisfactory. Our work consisted in adapting in mice the quantitative histomorphometry technique allowing the analysis of long bone vascularization, based on the infusion of barium sulfate, which was previously developed in the rat. In addition, we set up a reproducible Laser Doppler-Based technique for measurement of mouse tibia perfusion. In terms of structural analyses, and thank to 3D micro-Tomography imaging (Synchrotron or Nano scanner), we show the superiority of barium sulfate on a lead/silicon-Based contrast product (Microfil®)and its compatibility with common staining used in histology and with immuno-Histochemsitry of the vessel wall. We establish the reproducibility of the technique and propose a nomenclature. In terms of perfusion, we show, after having optimized the protocol by limiting the factors of variability, that Laser Doppler allows to measure, in a reproducible way, perfusion signals specific to bone. As long as the animal group size is appropriate (n=15), it becomes possible to carry out intergroup comparisons. These combined and integrated approaches, carried out on C57BL/6 and 129sv/Cd1 mice allowed us to show that (1) there is no correlation between perfusion and vascular density parameters (2) during ageing in males, the kinetics of bone vascularisation evolution differ according to the genetic background and that bone loss was not associated with decrease in perfusion in this model (3) that ovariectomy (OVX) induces a decrease in both bone vessel density and perfusion which precedes bone loss. Finally, we studied the structural and functional vascular effects of 1-84 parathyroid hormone and show that, as for its effects on bone mass, they depend on its mode of administration, intermittent or continuous and that they are not affected by OVX
Peterson, Kainoa John. "Mechanical Properties of Bone Due to SOST Expression: A 3-Point Bending Assessment of Murine Femurs." DigitalCommons@CalPoly, 2012. https://digitalcommons.calpoly.edu/theses/748.
Повний текст джерелаHeller, Amber Sky. "Histological Contributions to Species Identification of Calcined Bone from the Bull Brook and Morrill Point Mound Archaeological Sites." Fogler Library, University of Maine, 2011. http://www.library.umaine.edu/theses/pdf/HellerA2011.pdf.
Повний текст джерелаVermeulen, Emma Emmerenza. "Implementation of hazard analysis and critical control point (HACCP) system in a food service unit serving immuno-suppressed patient diets / E.E. Vermeulen." Thesis, North-West University, 2006. http://hdl.handle.net/10394/1179.
Повний текст джерелаThesis (M.Sc. (Dietetics))--North-West University, Potchefstroom Campus, 2007.
Cevik, Muammer Ozgur. "Effects Of Neuropeptide-y (npy) On Bone Metabolism As A Neuromediator- A Definitive Study." Master's thesis, METU, 2004. http://etd.lib.metu.edu.tr/upload/3/12604861/index.pdf.
Повний текст джерела#65533
6 M) and NPY dose 2 plus its inhibitor were applied together with hyaluronic acid (HA) into the intramedullary area of right tibia of Wistar rats. HA alone was administered as the control group. On three time points, day one, week one and week two after administration, the tibiae were collected and stored at &
#65533
20oC for analysis. Evaluation was performed via conventional radiography, dual energy X-ray absorbtiometry (DEXA), quantitative computerized tomography (QCT), three point bending test (TPB) and histology techniques. QCT was used to assess both atomic content and density of both medulla and cortex of tibiae. From DEXA results, it was observed that inhibition of NPY causes an increase in the bone mass from first day to second week. This phenomena was also observed in histology results so that new bone formation in the inhibitor administered bone was encountered at week two. In both medulla and cortex areas&
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atomic content, an increase in average effective atomic number was displayed after administration of NPY plus NPY inhibitor throughout two weeks. In addition, density of medulla of tibiae measured by QCT also revealed an increase in bone mass when inhibitor is applied throughout two weeks. As a result, overall evaluation of data obtained from DEXA, QCT and histological analysis revealed that NPY inhibits bone formation or have a pro-osteoclastic effect
inversely HA displayed osteogenic effect.
Cunliffe, Joanne. "The distance from the contact point to the crest of the bone to predict the presence of a black triangle." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/the-distance-from-the-contact-point-to-the-crest-of-the-bone-to-predict-the-presence-of-a-black-triangle(3c29822e-3068-443a-a017-08bbc86b03d9).html.
Повний текст джерелаRobertson, Galen Charles. "Quantification of Skeletal Phenotype Using Micro-CT and Mechanical Testing." Thesis, Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/4874.
Повний текст джерелаGranel, Henri. "Mise au point, caractérisation et optimisation d’hybrides organominéraux à base de polycaprolactone et bioverre pour la régénération tissulaire osseuse : Ingénierie tissulaire osseuse." Thesis, Université Clermont Auvergne (2017-2020), 2019. http://www.theses.fr/2019CLFAC106.
Повний текст джерелаIndisponible
Lemonnier, Sarah. "Rôle des phénomènes de transport dans la mise au point de stratégies thérapeutiques de réparation osseuse." Thesis, Paris Est, 2014. http://www.theses.fr/2014PEST1031/document.
Повний текст джерелаThis study aims to set up methods and tools to improve our understanding of the role played by transport phenomena (transport of cells, fluid and chemical species) in the development of new therapeutic protocols for bone reconstruction, using a double approach: experimental studies and numerical simulations. Hence, in the second chapter of this document, we have been able to link the intrinsic permeability of a porous medium – a key parameter regarding fluid transport through porous media – to the geometric structure of its pores. We have also highlighted the influence of electrochemical interactions on the flow of an ionic solution (such as physiologic fluids) through cortical bone, due to its porous structure and its chemical composition (presence of electrically charged fibers). These tools have then enabled us to analyze, at first glance, the experimental results of permeability tests conducted on ovin femoral periosteum, to identify the chemical-physical phenomena responsible for the specific behavior of this membrane (chapter 5). We also focused on the development of large bone implants coupling a mineral substitute and mesenchymal stem cells to enhance a volumic reconstruction of critical-sized bone defects. We have therefore designed, in chapter 3, a custom experimental set up that allows one to perform a reproducible cell seeding test on a porous scaffold and quantify the number of seeded cells as well as their viability rate. The experimental results provided by these tests have then initiated the numerical model exposed in chapter 4, that aims to highlight criteria to meet regarding the design of new bone substitutes that would enhance a homogeneous volumic tissue growth during the first stages of the extit [in vitro} development of coupled implants
Kalouche, Ibrahim. "Etude du comportement mécanique de la glène pour la mise au point d'un nouvel implant scapulaire à fixation sans ciment." Thesis, Paris 11, 2011. http://www.theses.fr/2011PA113003.
Повний текст джерелаTotal shoulder prostheses have a limited survival due mainly to the loosening of the glenoid implant. The purpose of this research is the contribution to the development of a new glenoid implant with cementless fixation.The first part concerned the characterization of the anisotropy and heterogeneity of cancellous bone of the glenoid by a compression experimental tests, this part has led to the drafting of a law of behavior of cancellous bone of the glenoid . The second part of this work has focused on finite element modeling of stress around the anchors of the glenoid implant.Simulation test results show the inability of the transversal plane of the glenoid to ensure effective press-fit fixation with stresses above strength properties of the cancellous bone with a minimal displacement. This calls into question the current modes of primary fixation of cementless implant. However, it appears that a change in the direction of loading would be beneficial for the primary fixation, which opens new perspectives for the design of a cementless prosthesis
Mannanal, Subash Kuriakose. "Biomechanical Evaluation of Hybrid Locked Plating for Humeral Shaft Fracture Fixation." University of Akron / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=akron1259180169.
Повний текст джерелаMurai, Igor Hisashi. "Efeitos do exercício físico associado à suplementação de creatina na massa óssea de ratas ovariectomizadas." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/39/39132/tde-06102014-091303/.
Повний текст джерелаThe current literature indicates exercise training as one of the most used nonpharmacological strategies in the treatment and prevention of conditions that affect the bone tissue. Moreover, studies indicate that creatine supplementation may exert positive effects on bone mass gain. Thus, the aim of this study was to investigate the preventive effects of exercise training associated with creatine supplementation on bone loss in ovariectomized rats. Thus, sixty-five female Wistar rats were matched by body weight and randomly assigned into five experimental groups, as follows: 1) shammed (SHAM); 2) ovariectomized (OVX), sedentary and placebo-supplemented rats (PL); 3) OVX, sedentary and creatine-supplemented rats (CR); 4) OVX, trained and placebo-supplemented rats (PL+TR) and 5) OVX rats, trained and creatinesupplemented rats (CR+TR). The animals were submitted to a downhill running training protocol performed on a treadmill and supplemented with creatine on daily basis via gavage. Bone density were evaluated pre and post-intervention to obtain bone mineral content (BMC) and bone mineral density (BMD) from whole body and regional area, as well as body composition. Right femur was removed to biomechanical assessment. After the intervention, PL+TR group had higher BMC and BMD compared to the PL group (p=0.004 and p=0.020, respectively), while the CR+TR group experienced greater increases in BMC and tended to increase BMD compared to the CR group (p=0.011 and p=0.064, respectively). Biomechanical assessment demonstrated significantly higher femur maximum strength of both trained groups (PL+TR and CR+TR) compared to SHAM group (p=0.024 and p=0.020, respectively), PL group (p<0.001 and p<0.001) and CR group (p=0.002 and p=0.002). With respect to femur stiffness, no significant difference was observed from the SHAM group compared to both trained groups (p=0.973 vs. PL+TR and p=0.998 vs. CR+TR), however, significant difference was observed when compared to sedentary groups (p=0.048 vs. PL and p=0.024 vs. CR), moreover, significant difference was observed when the PL group was compared to PL+TR group (p=0.009), as well as the CR group was significantly different compared to the CR+TR group (p=0.043). There were no significant differences between PL and CR groups and between PL+TR and CR+TR groups along the study. Thus, we conclude that creatine supplementation showed no isolated, nor additive effects when combined with exercise training, however, exercise training promoted positive effects on bone tissue, thus emphasizing its unique therapeutic role in attenuating the loss of bone mass
Beau, Mathieu. "Etude théorique du second point critique dans le gaz de Bose." Phd thesis, Université de la Méditerranée - Aix-Marseille II, 2010. http://tel.archives-ouvertes.fr/tel-00529394.
Повний текст джерелаEmery, Paul Ralph. "Multicomponent Cocrystals and Solid Solutions based on a Two-Point Hydrogen Bond Synthon." Digital WPI, 2009. https://digitalcommons.wpi.edu/etd-theses/102.
Повний текст джерелаPelini, Thomas. "Optical properties of point defects in hexagonal boron nitride." Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTS139.
Повний текст джерелаThe purpose of this thesis was to explore and caracterize optically the point defects in hexagonal boron nitride. The study of defects in this semiconductor is of fundamental importance firstly for the material science in which it plays a key role thanks to its lamellar structure (2D material) and its high thermal and chemical stability, and secondly for the quantum nanotechnology domain where its large bandgap (~ 6 eV) allows for exploiting deep levels point imperfections as «artificial atom» in the crystal lattice. During this thesis, defects in two spectral ranges have been studied: a first family emitting in the visible wavelengths, and a second one emitting in the ultraviolet range.Firstly, we made use of a scanning confocal microscope working in ambient conditions and at visible wavelengths. The recording of photoluminescence spatial maps permited to show the existence of localised hot spot of light, under the diffraction limit of the miscroscope, and emitting around 600 nm (2 eV). Time photon-correlation measurements revealed on one hand that we were dealing with single quantum emitters, and on the other hand allowed for probing the photodynamics of those systems, in particular at very long time-scale. Various photostability regimes are observed and discussed. Last but not least, power resolved study was also performed and demonstrated that a number of the emitters (~ 5%) are photo-stable at high excitation power and saturate at few millions counts per second: those point defects are one of the brightest single-photon source at room temperature in solid-state systems.Secondly, we explored the defects in the ultraviolet spectral range. A prerequisite to the engineering of defects in semiconductors for technological applications is the knowledge of their chemical origin. With this in mind, we studied shallow and deep levels in carbon-doped hBN samples by combining macro-photoluminescence and reflectance measurements. We showed the existence of new optically-active transitions (around 300 nm) and discussed the implication of carbon in these levels. The in-depth study of these levels have required the development of a new scanning micro-photoluminescence confocal microscope operating at 266 nm under cryogenic environment. The design and performances of the optical system are described, and the experimental challenges explained in details. Using this new setup, we went further into the examination of the deep levels. In particular, a study was carried out regarding the spatial correlation between these new spectral lines and the well-known point defect at 4.1 eV. Then, we used new crystals with isotopically-purified carbon doping as a strategy to investigate the long-standing question concerning the chemical origin of the 4.1 eV defect. Through this attempt, we brought to light the spatial dependence of the optical features for this specific emitter. Last but not least, we present our work dedicated to isolate the emission of a single 4.1 eV defect. We studied the photoluminescence of thin undoped flakes, pre-characterized with an electron microscope, that contain a low density of emitters, and inspected in particular their photostability in these thin crystals
Cartarius, Holger. "Exceptional points in atomic spectra and Bose-Einstein condensates." [S.l. : s.n.], 2008. http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-38343.
Повний текст джерелаRadu, Maria Teodora. "Thermodynamic characterization of heavy fermion systems and low dimensional quantum magnets near a quantum critical point." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2005. http://nbn-resolving.de/urn:nbn:de:swb:14-1130403549184-89465.
Повний текст джерелаMalatji, Kgashane Philip. "Development of mean concentration stimulation point for fermented Lantana Camara Phytonematicide on tomato production." Thesis, University of Limpopo, 2017. http://hdl.handle.net/10386/1918.
Повний текст джерелаRoot-knot nematodes (Meloidogyne species) are the major soil-borne pests of tomato (Solanum lycorpesicum) plants. Due to the global withdrawal of effective chemical nematicides from the agrochemical markets, nematodes are difficult to control under the production systems. Currently, botanicals are being researched and developed as alternative to chemical nematicides with promising results, although they have challenge of phytotoxicity. The objective of this study was to determine the Mean Concentration Stimulation Point (MCSP) of Tickberry (Lantana camara) extracts for tomato plant-infected with M. javanica. Treatments consisted of six levels of L. camara extracts, namely, 0, 2, 4, 6, 8 and 10% per pot, which were arranged in a randomised complete block design, with ten replicates. Tomato seedlings were inoculated with 2500 second-stage juveniles (J2S) of M. javanica at five days after transplanting, with treatments applied at seven days after inoculation. At 56 days after inoculation, L. camara extracts had positive effects on plant height, stem diameter, number of leaves, number of fruits and fruit mass, contributing 65, 74, 61, 25 and 61% in total treatment variation (TTV), respectively, under greenhouse conditions. Under microplot conditions, treatments contributed 55, 85, 61, 36 and 85% in TTV of the respective plant variables. Under greenhouse it contributed 60, 35 and 77% and 29, 79 and 70% under microplot on dry shoot mass, dry root mass and galling index respectively. Treatments did not have any effects on soil pH and electrical conductivity (EC). Under greenhouse conditions, treatments contributed 88, 94 and 92% in TTV of nematode in roots, soil and final population, respectively, whereas under microplot conditions 94, 97 and 95% in xvii TTV of the respective nematode stages. The derived mean concentration of L. camara extracts for tomato was 5.76 and 5.31% under microplot and greenhouse conditions, respectively. The overall sensitivity of tomato plants to L. camara extracts under microplot and greenhouse were 3 and 0, respectively. In conclusion Meloidogyne species can be managed using L. camara extracts 5.31 and 5.76% under glasshouse production and field production system respectively.
Abukharais, Ahlam [Verfasser], and Michael Vincent [Akademischer Betreuer] Swain. "Bond strength of different zirconia-veneering combinations (4-point bending interfacial fracture test) = Die Verbundfestigkeit in Vollkeramiksystemen (Vierpunkt Biegeprüfungssystem)." Freiburg : Universität, 2013. http://d-nb.info/1123479771/34.
Повний текст джерелаRafler, Mathias. "Martin-Dynkin Boundaries of the Bose Gas." Universität Potsdam, 2008. http://opus.kobv.de/ubp/volltexte/2011/5166/.
Повний текст джерелаBeauchez, Jérôme Gilbert. "L'Empreinte du poing dans la manufacture de soi : pour une anthropologie réflexive du corps pugilistique." Université Marc Bloch (Strasbourg) (1971-2008), 2007. http://www.theses.fr/2007STR20024.
Повний текст джерелаNyberg, Borrfors André. "Energy Decomposition Analysis of Neutral and Anionic Hydrogen Bonded Dimers Using a Point-Charge Approach." Thesis, KTH, Tillämpad fysikalisk kemi, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-288970.
Повний текст джерелаA large set of dimeric hydrogen bonds of the type A – H … B, where AH is an alkyne, alcohol, or thiol and B = [Br–, Cl–, NH3, HCN] are computed and evaluated using Kohn-Sham density functional theory together with the m062x/6-311+g(2df.2p) basis set. These complexes are also evaluated using a point charge (PC) approach (using the same method and basis set), where the atoms of the hydrogen bond acceptor B are substituted for charges that are optimized to reproduce the charge distribution of the molecule, with the purpose of separating and isolating the electrostatics- and polarization energy components of the interaction energies. Using this approach it was discovered that the complexation energy of hydrogen bonds (i.e.the interaction energy with the energy cost of nuclear deformation corrected for), independent on the nature of either monomer AH or B, are largely made up of electrostatics and polarization, while charge transfer, dispersion, and other rest terms only make up a small fraction of the total interaction. The composition of electrostatics and polarization vary depending on the type of monomers in the hydrogen bond, but their sum, the PC interaction energy, correlates linearly (ΔECompl = 0.85ΔEPC ) with R2 = 0.995 over an energy span of 0 < ΔECompl < 50 kcal mol–1. This is made even more remarkable by the inclusion of halogen bonded complexation energies in the same correlation without changing the correlation coefficient significantly, indicating that the two bond types are comprised of the same components even though they are remarkably different in origin.
Hémelaere, Rémy. "Mise au point de réactions tandems catalytiques incluant une étape d'isomérisation pour la synthèse de molécules naturelles." Thesis, Rennes 1, 2013. http://www.theses.fr/2013REN1S173/document.
Повний текст джерелаSome of the new challenges of modern synthetic chemistry are: atom economy, employment of catalytic processes, avoidance of toxic reactants and limitation of purification steps. A lot of work has been devoted to the development of tandem reactions. A new reactivity could be generated in a molecule thanks to an isomerisation (or migration) reaction of an alkene. This reaction often needs an hydride specie which comes from a transition metal catalyst. This PhD thesis is about the development of new tandem reactions in which at least one step is an isomerisation of an olefin. A great attention has been dedicated to the synthesis of vinylboronates especially with a cross-metathesis strategy. These intermediates are of great importance in organic chemistry and can be useful in a wide range of reactions. One of those reactions is the transformation of vinylboronates to allylboronates thanks to an isomerisation step. Allylboronates can then react with aldehydes to generate homoallylic alcohols with total diastereoselectivity. These new reactions have found applications in total synthesis of natural molecules with a 2,3-dihydrobenzofuran core
Feth, Shari. "A study of the promolecule radius of nitrides, oxides and sulfides and of the bond critical point properties of the electron density distribution in nitrides." Diss., This resource online, 1996. http://scholar.lib.vt.edu/theses/available/etd-05042006-164544/.
Повний текст джерелаDérue, Cédric. "Microscopie SIMS d'espèces diffusibles chez les végétaux : Mise au point d'une nouvelle méthode de préparation des échantillons et d'observation d'échantillons congelés hydratés." Rouen, 2005. http://www.theses.fr/2005ROUES031.
Повний текст джерелаThis work is a new contribution to the preparation of biological samples to study the distribution of diffusible ions using SIMS microscopy (Secondary Ion Mass Spectrometry). We compare the capabilities of the SIMS technique for imaging the inorganic cations with those of the others analytical imaging techniques. The main part of the work was to develop a new method for the dynamic SIMS analysis of frozen-hydrated samples under Fast Atom Bombardment (neutral oxygen). We describe the new cold stage built especially for our IMS 4F SIMS analyser. We show that referencing to the ice characteristic ions in the measurement of the relative sensitivity factors of Na, K, Mg and Ca cations gave non reliable results whatever the freezing mode (Plunge Freezing or High Pressure Freezing). Sensitivity factors relative to K gave, in contrast, results of reasonable accuracy. We show images of the cations distributions obtained with frozen-hydrated samples of ivy camomile and flax. We measured the inorganic ions ratios in the vacuoles of the cells of flax hypocotyl. These measurements revealed a high diversity in ionic contains of vacuoles even of adjacent cells. We also describe a new sample preparation method of plant samples without contact with a liquid to prevent the loss of diffusible species (“vapour phase method”). We used this method to appraise the SIMS applicability to boron studies in plants. We show that the SIMS technique has the potential for the simultaneous quantitative detection of the 10B and 11B isotopes in plant cells
Luu, Shirley, and Mersiha Selmanovic. "Min själ ville inte använda, men min kropp viker sig själv." Thesis, Malmö högskola, Fakulteten för hälsa och samhälle (HS), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-27031.
Повний текст джерелаPujol, Luca. "Mise au point d'un dispositif électroanalytique intégrant une étape de minéralisation et une étape de détection pour le dosage des métaux lourds." Thesis, Toulouse 3, 2016. http://www.theses.fr/2016TOU30352/document.
Повний текст джерелаHeavy metals industrial wastes involved the establishment of regulations concerning those toxic pollutants concentrations in surface water. Devices allowing heavy metals quantification already exist. Unfortunately, they revealed some gaps as their price, the need for qualified employees or even deferred results because of specific sampling procedures. Nowadays, in the heavy metals detection field, electroanalysis appears as a promising alternative. The work here discussed concerns the study of a global electroanalysis equipment, taking into account speciation issues related to organic matter presence, allowing heavy metals quantification in industrial runoffs of lead and nickel
Müller, Carina. "Assessment of hazard analysis and critical control points principles in primary school feeding schemes in the Western Region of Gauteng / Carina Müller." Thesis, North-West University, 2009. http://hdl.handle.net/10394/5004.
Повний текст джерелаThesis (M.Sc. (Dietetics))--North-West University, Potchefstroom Campus, 2009.
Charmot, Marie-Louise. "Étude et mise au point d'un procédé à boues activées, alimenté séquentiellement et adapté au traitement d'eaux usées fortement chargées." Vandoeuvre-les-Nancy, INPL, 1996. http://www.theses.fr/1996INPL084N.
Повний текст джерелаGautier, Brice Dupuy Jean-Claude. "Etude de la résolution en profondeur lors de l'analyse par spectrométrie de masse des ions secondaires détermination de la fonction de résolution pour le bore dans le silicium, mise au point d'une procédure de déconvolution et applications /." Villeurbanne : Doc'INSA, 1999. http://docinsa.insa-lyon.fr/these/pont.php?id=gautier.
Повний текст джерелаGautier, Brice. "Etude de la résolution en profondeur lors de l'analyse par spectrométrie de masse des ions secondaires : détermination de la fonction de résolution pour le bore dans le silicium, mise au point d'une procédure de déconvolution et applications." Lyon, INSA, 1997. http://theses.insa-lyon.fr/publication/1997ISAL0069/these.pdf.
Повний текст джерелаThe decreasing dimensions of the microelectronic devices involve the improvement of the capabilities of the analysis by Secondary Ions Mass Spectrometry (SIMS), especially in the domain of the depth resolution. We have reviewed the essential mechanisms which influence the depth resolution of the SIMS analysis. We have examined the theoretical foundations of the collisional mixing, which seems to be main mechanism responsible for the degradation of the depth resolution. A formalism based on an integral of convolution, which describe the modification of the original profiles due to the collisional mixing, allows to envisage the use of the deconvolution in order to correct the measured profiles. We have developed a theory which allows to explain the better depth resolution obtained in silicon matrices when an oxygen primary beam is used. This may be due to the pulverisation of oxygen atoms instead of silicon atoms initially present, when the primary beam atoms incorporate into the matrix
DAMANHURI, IMAM-SLAMET TRI-PADMI. "Contribution a la mise au point de tests d'activite biologique pour les dechets soumis a biodegradation." Paris 7, 1987. http://www.theses.fr/1987PA077029.
Повний текст джерелаZhao, Yi. "Degradable molecularly imprinted polymers-synthetic antibody mimics for the vectorization of active molecules." Thesis, Compiègne, 2015. http://www.theses.fr/2015COMP2189.
Повний текст джерелаMolecularly imprinted polymers (MIPs) are biomimetic synthetic receptors that possess two of the most important features of biological antibodies – the ability to recognize and bind specific target molecules. Owing to their easier preparation, lower cost, higher specifity and stability compared to antibodies, they have the potential to be widely applied for environemental and food analysis. Recently, MIPs also emerged in the biochemical field as diagnostic tools, chemicals traps to remove undesirable substance from the body, or drug delivery systems, where usually the combination of biocompatibility and degradability after its use is desirable. Here, we developed biochemically or enzymatically degradable MIPs, which have potential applications as activation-modulated drug delivery systems. In general, MIPs are prepared by radical polymerization of functional monomers and cross-linkers in the presence of a target molecule acting as template. Degradable MIPs were synthesized using cleavable cross-linkers containing a degradable group (disulfide bond or phosphate ester bond) or derived from a natural disaccharide. In the presence of a cleaving reagent (reducing agent or enzyme), the chemo or enzyme-sensitive bond could be cleaved, resulting in the degradation of the polymer matrix. The degraded polymers looses the binding sites structure resulting in the loss of recognition and binding capacity towards the target molecules, and thus in the release of bound molecules. These degradable MIPs provide new opportunities as “smart” vectors for controlled delivery of active molecules in biomedical applications. Finally, the biodegradation of the polymer backbone by bacteria was investigated
Tasnimi, A. A. "Prediction of forces within prestressed sections : The behavior of simply supported prestressed concrete beams with boned and unbonded tendons predicted by mathematical model and investigated by testing to destruction using two point load." Thesis, University of Bradford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384298.
Повний текст джерелаMüller, Torsten. "Untersuchungen zum Biegetragverhalten von Stahlfaserbeton und betonstahlbewehrtem Stahlfaserbeton unter Berücksichtigung des Einflusses von Stahlfaserart und Betonzusammensetzung." Doctoral thesis, Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-159513.
Повний текст джерелаAlengry, Jonathan. "Etude expérimentale et modélisation de la longueur de bon mélange. Application à la représentativité des points de prélèvement en conduit." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM4308/document.
Повний текст джерелаMonitoring of gaseous releases from nuclear installations in the environment and air cleaning efficiency measurement are based on regular measurements of concentrations of contaminants in outlet chimneys and ventilation systems. The concentration distribution may be heterogeneous at the measuring point if the distance setting of the mixing is not sufficient. The question is about the set up of the measuring point in duct and the error compared to the homogeneous concentration in case of non-compliance with this distance. This study defines the so-called "well mixing length" from laboratory experiments. The bench designed for these tests allowed to reproduce flows in long circular and rectangular ducts, each including a bend. An optical measurement technique has been developed, calibrated and used to measure the concentration distribution of a tracer injected in the flow. The experimental results in cylindrical duct have validated an analytical model based on the convection-diffusion equation of a tracer, and allowed to propose models of good mixing length and representativeness of sampling points. In rectangular duct, the acquired measures constitute a first database on the evolution of the homogenization of a tracer, in the perspective of numerical simulations exploring more realistic conditions for measurements in situ
Tran, Ngoc Nguyen. "Infeasibility detection and regularization strategies in nonlinear optimization." Thesis, Limoges, 2018. http://www.theses.fr/2018LIMO0059/document.
Повний текст джерелаThis thesis is devoted to the study of numerical algorithms for nonlinear optimization. On the one hand, we propose new strategies for the rapid infeasibility detection. On the other hand, we analyze the local behavior of primal-dual algorithms for the solution of singular problems. In the first part, we present a modification of an augmented Lagrangian algorithm for equality constrained optimization. The quadratic convergence of the new algorithm in the infeasible case is theoretically and numerically demonstrated. The second part is dedicated to extending the previous result to the solution of general nonlinear optimization problems with equality and inequality constraints. We propose a modification of a mixed logarithmic barrier-augmented Lagrangian algorithm. The theoretical convergence results and the numerical experiments show the advantage of the new algorithm for the infeasibility detection. In the third part, we study the local behavior of a primal-dual interior point algorithm for bound constrained optimization. The local analysis is done without the standard assumption of the second-order sufficient optimality conditions. These conditions are replaced by a weaker assumption based on a local error bound condition. We propose a regularization technique of the Jacobian matrix of the optimality system. We then demonstrate some boundedness properties of the inverse of these regularized matrices, which allow us to prove the superlinear convergence of our algorithm. The last part is devoted to the local convergence analysis of the primal-dual algorithm used in the first two parts of this thesis. In practice, it has been observed that this algorithm converges rapidly even in the case where the constraints do not satisfy the Mangasarian-Fromovitz constraint qualification. We demonstrate the superlinear and quadratic convergence of this algorithm without any assumption of constraint qualification
Tsiamantas, Christos. "Synthesis and structure-stability relationship of aromatic helical foldamers." Thesis, Bordeaux, 2015. http://www.theses.fr/2015BORD0029/document.
Повний текст джерелаAt the molecular level, the functions of helical patterns are often directly associated with the stability of thesearchitectures, (in α-helices). For example, upon removal of such an entity from the protein’s tertiary structure,the peptidic helix becomes flexible and thus inactive. In order to control the rigidity of these architectures,several strategies have been used and the construction of completely artificial well folded molecules known asfoldamers is one them. Our group mainly focuses on helical aromatic oligoamide foldamers and to dateseveral studies have been carried out to investigate factors affecting the helical stability; the influence ofoligomer length, solvent effects and the effect of aliphatic linkers within a helical aromatic sequence.In the present study we investigate the helical propensity of five commonly used aromatic monomers infoldamer synthesis and by using NMR spectroscopy, X-ray crystallography and dynamic chiral HPLC weevaluate their contribution in helical stability. Additionally, inspired by the role of disulfide bonds in proteins wedecided to explore their effect on helical stability. For this reason intra- and inter-molecularly disulfide bondedcompounds were designed and synthesized. Their stability was studied using NMR spectroscopy, chiral HPLCand CD experiments.Finally, the synthesis of mono-disperse helical strings of polymeric dimensions through a convergent, segmenttripling strategy has been developed. This protection/deprotection free synthesis was carried out byconnecting oligomeric blocks via a labile anhydride functionality
Alsaleh, Sultan Abdullah. "Investigating Riyadh's public health inspectors' ability to conduct risk-based food inspection, and their professional needs: A mixed-methods research study." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/208321/1/Sultan%20Abdullah%20R_Alsaleh_Thesis.pdf.
Повний текст джерелаBartolo, Nicola. "Matter waves in reduced dimensions : dipolar-induced resonances and atomic artificial crystals." Thesis, Montpellier 2, 2014. http://www.theses.fr/2014MON20177/document.
Повний текст джерелаThe experimental achievement of Bose-Einstein condensation and Fermi degeneracy with ultracold gases boosted tremendous progresses both in theoretical methods and in the development of new experimental tools. Among them, intriguing possibilities have been opened by the implementation of optical lattices: periodic potentials for neutral atoms created by interfering laser beams. Degenerate gases in optical lattices can be forced in highly anisotropic traps, reducing the effective dimensionality of the system. From a fundamental point of view, the behavior of matter waves in reduced dimensions sheds light on the intimate properties of interparticle interactions. Furthermore, such reduced-dimensional systems can be engineered to quantum-simulate fascinating solid state systems, like bidimensional crystals, in a clean and controllable environment. Motivated by the exciting perspectives of this field, we devote this Thesis to the theoretical study of two systems where matter waves propagate in reduced dimensions.The long-range and anisotropic character of the dipole-dipole interaction critically affects the behavior of dipolar quantum gases. The continuous experimental progresses in this flourishing field might lead very soon to the creation of degenerate dipolar gases in optical potentials. In the first part of this Thesis, we investigate the emergence of a single dipolar-induced resonance in the two-body scattering process in quasi-one dimensional geometries. We develop a two-channel approach to describe such a resonance in a highly elongated cigar-shaped harmonic trap, which approximates the single site of a quasi-one- dimensional optical lattice. At this stage, we develop a novel atom-dimer extended Bose- Hubbard model for dipolar bosons in this quasi-one-dimensional optical lattice. Hence we investigate the T=0 phase diagram of the model by exact diagonalization of a small- sized system, highlighting the effects of the dipolar-induced resonance on the many-body behavior in the lattice.In the second part of the Thesis, we present a general scheme to realize cold-atom quantum simulators of bidimensional atomic crystals, based on the possibility to independently trap two different atomic species. The first one constitutes a two-dimensional matter wave which interacts only with the atoms of the second species, deeply trapped around the nodes of a two-dimensional optical lattice. By introducing a general analytic approach, we investigate the matter-wave transport properties. We propose some illustrative appli- cations to both Bravais (square, triangular) and non-Bravais (graphene, kagomé) lattices, studying both ideal periodic systems and experimental-sized, eventually disordered, ones. The features of the artificial atomic crystal critically depend on the two-body interspecies interaction strength, which is shown to be widely tunable via 0D-2D mixed-dimensional resonances
Cazorla, Clément. "Étude de la réactivité polyvalente des composés borés : de la fluoration électrophile à la synthèse d’amides par substitution nucléophile oxydante ; O-alkylation de dérivés phénoliques par substitution nucléophile : vers la mise au point d’un système éco-compatible." Thesis, Lyon 1, 2011. http://www.theses.fr/2011LYO10144/document.
Повний текст джерелаThis thesis describes the study of the reactivity of boron compounds and the O-alkylation of aromatic alcohols. The use of boronic derivatives increased considerably over the past decades. There are used as cross-coupling partners in the Suzuki reaction and for 1,4 rhodium-catalyzed addition reaction. The nucleophilic nature of these compounds was induced by the C-B bond polarization. This peculiar reactivity was studied for the C-F bond formation. The use of Selectfluor® as fluorinating agent leads to good yields. Nevertheless, the polarity of the C-B bond could be reversed by oxidative nucleophilic substitution. Thus, C–N bond could be formed from nitriles and potassium trifluoroborate salts promoted by Cu(OAc)2 in the presence of BF3.OEt2. Due to the importance of ether chemistry in organic synthesis, the O-alkylation of phenol derivatives was achieved in the laboratory. From a stoichiometric amount of Lewis acid, BF3.OEt2, a catalytic system was developed involving cerium triflate. Then, the focus on green chemistry led to use a heterogeneous catalyst. Where Nafion® NR50 appears as a suitable catalyst for the ether synthesis
Simon, Bruno. "Effects of tidal bores on turbulent mixing : a numerical and physical study in positive surges." Phd thesis, Université Sciences et Technologies - Bordeaux I, 2013. http://tel.archives-ouvertes.fr/tel-00965582.
Повний текст джерелаMorin-Grognet, Sandrine. "Etude structurale et magnétique de rubans Fe-(Cu)-Si-B-(Nb, Zr, Mo) amorphes et nanocristallins. Effet d'un traitement thermochimique de nitruration." Rouen, 1999. http://www.theses.fr/1999ROUES012.
Повний текст джерелаVan, Vliet Miranda. "The effect of advanced glycation endproduct accumulation on bone." Thesis, 2017. https://hdl.handle.net/2144/23999.
Повний текст джерелаSheng-Min, Kao, and 高聖閔. "Four-Point-Bending Simulation Analysis of Dynamic Compression Bone Plate of Human Lower Limb." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/65512948380701518567.
Повний текст джерела正修科技大學
機電工程研究所
103
In Taiwan, there are thirty thousand patients treated long bone fracture every year. The system of bone plate and screws is one of the most commonly treatment method for bone trauma. In addition to bone plate for the fracture fixing also has to share bone’s loading, therefor the bone plate strength is a priority factor for this system design. In this research, based on ASTM F382 standard, a four-point bending test simulation model of the dynamic compression bone plate has been developed for human lower limb by using SolidWorks first. Then through the ANSYS software to obtain the load-displacement cure and in accordance with the ASTM F382 specifications the bone plate bending strength and bending structural stiffness can be calculated. Using CNC milling machine to complete bone plate processing for four-point bending test, Finally, compare the simulation results with the four-point bending test data to evaluate this four-point bending test simulation model. The simulation result of the bone plate bending strength has 5.37 percent difference to its four-point bending test data, and bending structural stiffness (EIc) has 13% difference, all the results differences are within an acceptable range, showing that the four-point bending test model developed in this study is acceptable. Because Ti-6Al-4V alloy is not easy to machining and very expensive, this study could provide a FEM model to quickly verify bone plate’s strength, to shorten design process and reduce the development costs effectively.
Simpson, J. P., K. E. H. Penkman, B. Demarchi, Hannah E. C. Koon, M. J. Collins, J. Thomas-Oates, B. Shapiro, M. Mark, and J. Wilson. "The effects of demineralisation and sampling point variability on the measurement of glutamine deamidation in type I collagen extracted from bone." 2016. http://hdl.handle.net/10454/10160.
Повний текст джерелаThe level of glutamine (Gln) deamidation in bone collagen provides information on the diagenetic history of bone but, in order to accurately assess the extent of Gln deamidation, it is important to minimise the conditions that may induce deamidation during the sample preparation. Here we report the results of a preliminary investigation of the variability in glutamine deamidation levels in an archaeological bone due to: a) sampling location within a bone; b) localised diagenesis; and c) sample preparation methods. We then investigate the effects of pre-treatment on three bone samples: one modern, one Medieval and one Pleistocene. The treatment of bone with acidic solutions was found to both induce deamidation and break down the collagen fibril structure. This is particularly evident in the Pleistocene material (~80,000 years BP) considered in this study. We show that ethylenediaminetetraacetic acid (EDTA), when used as an alternative to hydrochloric acid (HCl) demineralisation, induces minimal levels of deamidation and maintains the collagen fibril structure. Areas of bone exhibiting localised degradation are shown to be correlated with an increase in the levels of Gln deamidation. This indicates that the extent of Gln deamidation could provide a marker for diagenesis but that sampling is important, and that, whenever possible, subsamples should be taken from areas of the bone that are visually representative of the bone as a whole. Although validation of our observations will require analysis of a larger sample set, deamidation measurements could be a valuable screening tool to evaluate the suitability of bone for further destructive collagen analyses such as isotopic or DNA analysis, as well as assessing the overall preservation of bone material at a site. The measure of bone preservation may be useful to help conservators identify bones that may require special long-term storage conditions.
NERC (NE/J500197/1), Yorkshire Forward - Northern Way Initiative, Science City York, Gordon and Betty Moore Foundation, Leverhulme Trust
Meyers, Julia Luba. "The relationship between proximal long bone shape and activity among four hunter-gatherer populations." Thesis, 2017. https://dspace.library.uvic.ca//handle/1828/8460.
Повний текст джерелаGraduate
Eom, Dae Seok. "The role of bone morphogenetic proteins in the development of the vertebrate midbrain." Thesis, 2010. http://hdl.handle.net/2152/ETD-UT-2010-12-2435.
Повний текст джерелаtext