Статті в журналах з теми "Birinapant"
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Fetterly, Gerald J., Biao Liu, Neil N. Senzer, Ravi K. Amaravadi, Russell J. Schilder, Lainie P. Martin, Patricia LoRusso, et al. "Clinical pharmacokinetics of the Smac-mimetic birinapant (TL32711) as a single agent and in combination with multiple chemotherapy regimens." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): 3029. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.3029.
Повний текст джерелаNoonan, Anne M., Amanda Cousins, David Anderson, Kristen P. Zeligs, Kristen Bunch, Lidia Hernandez, Yusuke Shibuya, et al. "Matrix Drug Screen Identifies Synergistic Drug Combinations to Augment SMAC Mimetic Activity in Ovarian Cancer." Cancers 12, no. 12 (December 15, 2020): 3784. http://dx.doi.org/10.3390/cancers12123784.
Повний текст джерелаCarter, Bing Z., Po Yee Mak, Duncan H. Mak, Vivian Ruvolo, Rodrigo Jacamo, Steven M. Kornblau, and Michael Andreeff. "Apoptosis Repressor with Caspase Recruitment Domain Is Regulated by the cIAP1-NIK Axis and Confers Resistance to SMAC Mimetic Birinapant-Induced Cell Death in AML." Blood 120, no. 21 (November 16, 2012): 534. http://dx.doi.org/10.1182/blood.v120.21.534.534.
Повний текст джерелаSmith, Malcolm A., Hernan Carol, Kathryn Evans, Jennifer Richmond, Min Kang, C. Patrick Reynolds, Srinivas Chunduru та ін. "Birinapant (TL32711), a Small Molecule Smac Mimetic, Induces Regressions in Childhood Acute Lymphoblastic Leukemia (ALL) Xenografts That Express TNFα and Synergizes with TNFα in Vitro – A Report From the Pediatric Preclinical Testing Program (PPTP)". Blood 120, № 21 (16 листопада 2012): 3565. http://dx.doi.org/10.1182/blood.v120.21.3565.3565.
Повний текст джерелаWang, Beatrice T., Melanie Desbois, Susan E. Calhoun, Thomas J. Matthew, Poonam Yakkundi, Ling Wang, Xingjie Chen, et al. "Abstract 1068: Anti-DR5 agonist IgM antibody IGM-8444 combined with SMAC mimetic birinapant induces strong synergistic tumor cytotoxicity." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1068. http://dx.doi.org/10.1158/1538-7445.am2022-1068.
Повний текст джерелаJoshi, Indira D., and Mitchell R. Smith. "Birinapant Enhances Bendamustine-Induced Apoptosis In Activated B Cell-Diffuse Large Cell Lymphoma Cells." Blood 122, no. 21 (November 15, 2013): 5150. http://dx.doi.org/10.1182/blood.v122.21.5150.5150.
Повний текст джерелаMorrish, Emma, Liana Mackiewicz, Natasha Silke, Marc Pellegrini, John Silke, Gabriela Brumatti, and Gregor Ebert. "Combinatorial Treatment of Birinapant and Zosuquidar Enhances Effective Control of HBV Replication In Vivo." Viruses 12, no. 8 (August 17, 2020): 901. http://dx.doi.org/10.3390/v12080901.
Повний текст джерелаMorrish, Emma, Anthony Copeland, Donia M. Moujalled, Jason A. Powell, Natasha Silke, Ann Lin, Kate E. Jarman, et al. "Clinical MDR1 inhibitors enhance Smac-mimetic bioavailability to kill murine LSCs and improve survival in AML models." Blood Advances 4, no. 20 (October 20, 2020): 5062–77. http://dx.doi.org/10.1182/bloodadvances.2020001576.
Повний текст джерелаSchilder, Russell J., Mark Albertella, James Fredric Strauss, Malin Sydvander, Dung T. Le, Stefan Norin, Monica M. Mita, et al. "Determination of the recommended phase II dose of birinapant in combination with pembrolizumab: Results from the dose-escalation phase of BPT-201." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): 2506. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.2506.
Повний текст джерелаLalaoui, Najoua, Delphine Merino, Goknur Giner, François Vaillant, Diep Chau, Lin Liu, Tobias Kratina, et al. "Targeting triple-negative breast cancers with the Smac-mimetic birinapant." Cell Death & Differentiation 27, no. 10 (April 27, 2020): 2768–80. http://dx.doi.org/10.1038/s41418-020-0541-0.
Повний текст джерелаKandeel, Mahmoud, Jinsoo Kim, Mahmoud Fayez, Yukio Kitade, and Hyung-Joo Kwon. "Antiviral drug discovery by targeting the SARS-CoV-2 polyprotein processing by inhibition of the main protease." PeerJ 10 (February 8, 2022): e12929. http://dx.doi.org/10.7717/peerj.12929.
Повний текст джерелаRitchie, Ellen K., Apurv Agrawal, Kashyap B. Patel, Seth Rosen, Amy Law, Jeffrey M. Skolnik, and Ashkan Lashkari. "A Phase 2 Study of Birinapant in Combination with 5-Azacitadine in Patients with Myelodysplastic Syndrome Who Are Naïve to 5-Azacitadine: A Preliminary Analysis of Phase 2a." Blood 126, no. 23 (December 3, 2015): 2904. http://dx.doi.org/10.1182/blood.v126.23.2904.2904.
Повний текст джерелаFrey, Noelle V., Selina Luger, James Mangan, Alexis Zebrowski, Alison W. Loren, Hans Minderman, John Baird, et al. "A Phase I Study Using Single Agent Birinapant in Patients with Relapsed Myelodysplastic Syndrome and Acute Myelogenous Leukemia." Blood 124, no. 21 (December 6, 2014): 3758. http://dx.doi.org/10.1182/blood.v124.21.3758.3758.
Повний текст джерелаBorthakur, Gautam, James M. Foran, Eunice S. Wang, Amol Rakkar, Hans Minderman, Jennifer Burns, Michael Andreeff, and Raoul Tibes. "A Phase 1b Study of Birinapant in Combination with 5-Azacitadine in Patients with Myelodysplastic Syndrome Who Are Naïve, Refractory or Have Relapsed to 5-Azacitadine." Blood 126, no. 23 (December 3, 2015): 93. http://dx.doi.org/10.1182/blood.v126.23.93.93.
Повний текст джерелаEbert, Gregor, Cody Allison, Simon Preston, James Cooney, Jesse G. Toe, Michael D. Stutz, Samar Ojaimi, et al. "Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis." Proceedings of the National Academy of Sciences 112, no. 18 (April 20, 2015): 5803–8. http://dx.doi.org/10.1073/pnas.1502400112.
Повний текст джерелаBorthakur, Gautam, James M. Foran, Eunice S. Wang, Amol Rakkar, Steven Hager, Noelle V. Frey, Michael Andreeff, et al. "A Phase 1b/2a Study of Birinapant in Combination with 5-Azacitadine in Patients with Myelodysplastic Syndrome Who Are Naïve, Refractory to or Have Relapsed on 5-Azacitadine: a Preliminary Analysis." Blood 124, no. 21 (December 6, 2014): 3263. http://dx.doi.org/10.1182/blood.v124.21.3263.3263.
Повний текст джерелаToni, Tiffany, Ethan Morgan, Ramya Viswanathan, Xinping Yang, Hui Cheng, and Carter Van Waes. "Abstract 2997: Combination treatment with cIAP and WEE1 inhibitors exhibits synergism in HPV-positive and HPV-negative head and neck squamous carcinoma cells." Cancer Research 82, no. 12_Supplement (June 15, 2022): 2997. http://dx.doi.org/10.1158/1538-7445.am2022-2997.
Повний текст джерелаMurray, Susan E., Brittany Ligman, Ashley Burton, and Claire Kearney. "The effect of SMAC mimetics on human T cell activation." Journal of Immunology 204, no. 1_Supplement (May 1, 2020): 246.13. http://dx.doi.org/10.4049/jimmunol.204.supp.246.13.
Повний текст джерелаDeng, Yijun, Thomas Haimowitz, Matthew G. LaPorte, Susan R. Rippin, Matthew D. Alexander, Pavan Tirunahari Kumar, Mukta S. Hendi, Yu-Hua Lee, and Stephen M. Condon. "Electrophilic Oxidation and [1,2]-Rearrangement of the Biindole Core of Birinapant." ACS Medicinal Chemistry Letters 7, no. 3 (January 13, 2016): 318–23. http://dx.doi.org/10.1021/acsmedchemlett.5b00461.
Повний текст джерелаSchilder, Russell J., Mark Albertella, James Strauss, Malin Sydvander, Santosh M. Nair, Kingsley Urakpo, Stefan Norin, and John Öhd. "A phase 1/2 study with birinapant in combination with pembrolizumab." Journal of Clinical Oncology 36, no. 15_suppl (May 20, 2018): TPS3131. http://dx.doi.org/10.1200/jco.2018.36.15_suppl.tps3131.
Повний текст джерелаGong, Tingting, Yujun Cai, Fengze Sun, Jiaxin Chen, Zhongzhen Su, Xintao Shuai, and Hong Shan. "A nanodrug incorporating siRNA PD-L1 and Birinapant for enhancing tumor immunotherapy." Biomaterials Science 9, no. 23 (2021): 8007–18. http://dx.doi.org/10.1039/d1bm01299a.
Повний текст джерелаKrepler, Clemens, Srinivas K. Chunduru, Molly B. Halloran, Xu He, Min Xiao, Adina Vultur, Jessie Villanueva, et al. "The Novel SMAC Mimetic Birinapant Exhibits Potent Activity against Human Melanoma Cells." Clinical Cancer Research 19, no. 7 (February 12, 2013): 1784–94. http://dx.doi.org/10.1158/1078-0432.ccr-12-2518.
Повний текст джерелаWerner, Thomas A., Inga Nolten, Levent Dizdar, Jasmin C. Riemer, Sina C. Schütte, Pablo E. Verde, Katharina Raba, Matthias Schott, Wolfram T. Knoefel, and Andreas Krieg. "IAPs cause resistance to TRAIL-dependent apoptosis in follicular thyroid cancer." Endocrine-Related Cancer 25, no. 3 (March 2018): 295–308. http://dx.doi.org/10.1530/erc-17-0479.
Повний текст джерелаRichmond, Jennifer, Alissa Robbins, Kathryn Evans, Dominik Beck, Raushan T. Kurmasheva, Catherine A. Billups, Hernan Carol, et al. "Acute Sensitivity of Ph-like Acute Lymphoblastic Leukemia to the SMAC-Mimetic Birinapant." Cancer Research 76, no. 15 (June 14, 2016): 4579–91. http://dx.doi.org/10.1158/0008-5472.can-16-0523.
Повний текст джерелаZhu, Xu, Robert M. Straubinger, and William J. Jusko. "Mechanism-based mathematical modeling of combined gemcitabine and birinapant in pancreatic cancer cells." Journal of Pharmacokinetics and Pharmacodynamics 42, no. 5 (August 8, 2015): 477–96. http://dx.doi.org/10.1007/s10928-015-9429-x.
Повний текст джерелаLa, V., R. Fujikawa, D. M. Janzen, L. Bainvoll, M. Nunez, and S. Memarzadeh. "Birinapant sensitizes platinum-resistant carcinomas with high levels of cIAP to carboplatin therapy." Gynecologic Oncology 145 (June 2017): 20. http://dx.doi.org/10.1016/j.ygyno.2017.03.062.
Повний текст джерелаShu, Xiaoming, Zhejiang Zhu, Dan Cao, Li Zheng, Fang Wang, Heying Pei, Jiaolin Wen, et al. "PEG-derivatized birinapant as a nanomicellar carrier of paclitaxel delivery for cancer therapy." Colloids and Surfaces B: Biointerfaces 182 (October 2019): 110356. http://dx.doi.org/10.1016/j.colsurfb.2019.110356.
Повний текст джерелаChang, Yung-Chieh, and Chun Hei Antonio Cheung. "An Updated Review of Smac Mimetics, LCL161, Birinapant, and GDC-0152 in Cancer Treatment." Applied Sciences 11, no. 1 (December 31, 2020): 335. http://dx.doi.org/10.3390/app11010335.
Повний текст джерелаZhu, Xu, Sheryl Trueman, Robert M. Straubinger, and William J. Jusko. "Physiologically-based pharmacokinetic and pharmacodynamic models for gemcitabine and birinapant in pancreatic cancer xenografts." Journal of Pharmacokinetics and Pharmacodynamics 45, no. 5 (August 1, 2018): 733–46. http://dx.doi.org/10.1007/s10928-018-9603-z.
Повний текст джерелаGu, Shengqing, Wubing Zhang, Xiaoqing Wang, Peng Jiang, Nicole Traugh, Ziyi Li, Clifford Meyer, et al. "700 Increasing MHC-I expression to potentiate immune checkpoint blockade therapy." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (November 2021): A728. http://dx.doi.org/10.1136/jitc-2021-sitc2021.700.
Повний текст джерелаZhao, Li, Guoshan Yang, Hao Bai, Minghui Zhang, and Dongcheng Mou. "NCTD promotes Birinapant-mediated anticancer activity in breast cancer cells by downregulation of c-FLIP." Oncotarget 8, no. 16 (March 2, 2017): 26886–95. http://dx.doi.org/10.18632/oncotarget.15848.
Повний текст джерелаAnderson, D. M., K. P. Zeligs, K. P. Bunch, L. Hernandez, and C. M. Annunziata. "Mechanistic basis for synergy between SMAC-mimetic birinapant and chemotherapeutic agents: Insights for clinical development." Gynecologic Oncology 154 (June 2019): 87. http://dx.doi.org/10.1016/j.ygyno.2019.04.204.
Повний текст джерелаSong, E. Z., X. Wang, B. I. Philipson, Q. Zhang, R. Thokala, Z. A. Binder, D. O’Rourke, H. Song, and M. Milone. "Immunotherapy: THE IAP INHIBITOR BIRINAPANT ENHANCES CAR-T CELL THERAPY FOR GLIOBLASTOMA BY OVERCOMING ANTIGEN HETEROGENEITY." Cytotherapy 24, no. 5 (May 2022): S124. http://dx.doi.org/10.1016/s1465-3249(22)00334-6.
Повний текст джерелаCondon, Stephen M., Yasuhiro Mitsuuchi, Yijun Deng, Matthew G. LaPorte, Susan R. Rippin, Thomas Haimowitz, Matthew D. Alexander, et al. "Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies." Journal of Medicinal Chemistry 57, no. 9 (April 15, 2014): 3666–77. http://dx.doi.org/10.1021/jm500176w.
Повний текст джерелаNoonan, A. M., J. Chen, M. Herrmann, and C. M. Annunziata. "97 Birinapant, a Novel Smac Mimetic, Activates Apoptosis in NF-kappaB-dependent Gynecologic Cancer Cell Lines." European Journal of Cancer 48 (November 2012): 31. http://dx.doi.org/10.1016/s0959-8049(12)71895-6.
Повний текст джерелаEytan, Danielle F., Grace E. Snow, Sophie G. Carlson, Stephen Schiltz, Zhong Chen та Carter Van Waes. "Combination effects of SMAC mimetic birinapant with TNFα, TRAIL, and docetaxel in preclinical models of HNSCC". Laryngoscope 125, № 3 (28 листопада 2014): E118—E124. http://dx.doi.org/10.1002/lary.25056.
Повний текст джерелаSeong, Daehyeon, Manhyung Jeong, Jinho Seo, Ji-Yoon Lee, Chi Hyun Hwang, Ho-Chul Shin, Jeong Yoon Shin, et al. "Identification of MYC as an antinecroptotic protein that stifles RIPK1–RIPK3 complex formation." Proceedings of the National Academy of Sciences 117, no. 33 (August 4, 2020): 19982–93. http://dx.doi.org/10.1073/pnas.2000979117.
Повний текст джерелаAmaravadi, Ravi K., Russell J. Schilder, Lainie P. Martin, Myron Levin, Martin A. Graham, David E. Weng, and Alex A. Adjei. "A Phase I Study of the SMAC-Mimetic Birinapant in Adults with Refractory Solid Tumors or Lymphoma." Molecular Cancer Therapeutics 14, no. 11 (September 2, 2015): 2569–75. http://dx.doi.org/10.1158/1535-7163.mct-15-0475.
Повний текст джерелаZhu, D. L., and L. Y. Shuai. "The effects of birinapant on proliferation and invasion and its corresponding mechanism in MGC-803 gastric cancer cells." Bulletin of Experimental Biology and Medicine 171, no. 1 (2021): 73–79. http://dx.doi.org/10.47056/0365-9615-2021-171-1-73-79.
Повний текст джерелаZakaria, Z., A. Tivnan, L. Flanagan, D. W. Murray, M. Salvucci, B. W. Stringer, B. W. Day, et al. "Patient-derived glioblastoma cells show significant heterogeneity in treatment responses to the inhibitor-of-apoptosis-protein antagonist birinapant." British Journal of Cancer 114, no. 2 (December 10, 2015): 188–98. http://dx.doi.org/10.1038/bjc.2015.420.
Повний текст джерелаDeng, Yijun, Qiuzhe Xie, Matthew G. LaPorte, Anna T. A. Chasnoff, Mark A. Mortensen, Debasis Patra, Seth A. Putrelo, et al. "Process Development and Synthesis of Birinapant: Large Scale Preparation and Acid-Mediated Dimerization of the Key Indole Intermediate." Organic Process Research & Development 20, no. 2 (January 15, 2016): 242–52. http://dx.doi.org/10.1021/acs.oprd.5b00390.
Повний текст джерелаPark, Eun Jung, Hae Dong Kim, Eun Kyoung Choi, Kwang-Lae Hoe, and Dong-Uk Kim. "Co-treatment of birinapant with TRAIL synergistically induces apoptosis by downregulating cFLIP(L) in MDA-MB-453 cell lines." Biochemical and Biophysical Research Communications 533, no. 3 (December 2020): 289–95. http://dx.doi.org/10.1016/j.bbrc.2020.09.031.
Повний текст джерелаBrumatti, Gabriela, Chunyan Ma, Najoua Lalaoui, Nhu-Y. Nguyen, Mario Navarro, Maria C. Tanzer, Jennifer Richmond, et al. "The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia." Science Translational Medicine 8, no. 339 (May 18, 2016): 339ra69. http://dx.doi.org/10.1126/scitranslmed.aad3099.
Повний текст джерелаZhu, Xu, Xiaomeng Shen, Jun Qu, Robert M. Straubinger, and William J. Jusko. "Multi-Scale Network Model Supported by Proteomics for Analysis of Combined Gemcitabine and Birinapant Effects in Pancreatic Cancer Cells." CPT: Pharmacometrics & Systems Pharmacology 7, no. 9 (August 9, 2018): 549–61. http://dx.doi.org/10.1002/psp4.12320.
Повний текст джерелаAmaravadi, Ravi K., Neil N. Senzer, Lainie P. Martin, Russell J. Schilder, Patricia LoRusso, Kyriakos P. Papadopoulos, David Edward Weng, Martin Graham, and Alex A. Adjei. "A phase I study of birinapant (TL32711) combined with multiple chemotherapies evaluating tolerability and clinical activity for solid tumor patients." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 2504. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.2504.
Повний текст джерелаGaritano-Trojaola, Andoni, Eva Teufel, Matteo Claudio Da Via', Ana Sancho, Nadine Rodhes, Thorsten Stuehmer, Santiago Barrio Garcia, et al. "The Role of NRAS G12D Mutations in the Response to Conventional Chemotherapy and 5-Azacitidine in Secondary AML." Blood 132, Supplement 1 (November 29, 2018): 5148. http://dx.doi.org/10.1182/blood-2018-99-118484.
Повний текст джерелаWang, Xue, Jin Niu, Jun Li, Xiaomeng Shen, Shichen Shen, Robert M. Straubinger, and Jun Qu. "Temporal Effects of Combined Birinapant and Paclitaxel on Pancreatic Cancer Cells Investigated via Large-Scale, Ion-Current-Based Quantitative Proteomics (IonStar)." Molecular & Cellular Proteomics 17, no. 4 (January 22, 2018): 655–71. http://dx.doi.org/10.1074/mcp.ra117.000519.
Повний текст джерелаEytan, Danielle F., Grace E. Snow, Sophie Carlson, Adeeb Derakhshan, Anthony Saleh, Stephen Schiltz, Hui Cheng, et al. "SMAC Mimetic Birinapant plus Radiation Eradicates Human Head and Neck Cancers with Genomic Amplifications of Cell Death Genes FADD and BIRC2." Cancer Research 76, no. 18 (July 28, 2016): 5442–54. http://dx.doi.org/10.1158/0008-5472.can-15-3317.
Повний текст джерелаCrawford, Nyree, Manuela Salvucci, Christian T. Hellwig, Frank A. Lincoln, Ruth E. Mooney, Carla L. O’Connor, Jochen HM Prehn, Daniel B. Longley, and Markus Rehm. "Simulating and predicting cellular and in vivo responses of colon cancer to combined treatment with chemotherapy and IAP antagonist Birinapant/TL32711." Cell Death & Differentiation 25, no. 11 (March 2, 2018): 1952–66. http://dx.doi.org/10.1038/s41418-018-0082-y.
Повний текст джерелаSenzer, Neil N., Patricia LoRusso, Lainie P. Martin, Russell J. Schilder, Ravi K. Amaravadi, Kyriakos P. Papadopoulos, Zdenka E. Segota, David Edward Weng, Martin Graham, and Alex A. Adjei. "Phase II clinical activity and tolerability of the SMAC-mimetic birinapant (TL32711) plus irinotecan in irinotecan-relapsed/refractory metastatic colorectal cancer." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 3621. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.3621.
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