Дисертації з теми "Biophysical stimulation"
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Hannay, Gwynne George. "Mechanical and electrical environments to stimulate bone cell development." Thesis, Queensland University of Technology, 2006. https://eprints.qut.edu.au/16285/1/Gwynne_Hannay_Thesis.pdf.
Повний текст джерелаHannay, Gwynne George. "Mechanical and electrical environments to stimulate bone cell development." Queensland University of Technology, 2006. http://eprints.qut.edu.au/16285/.
Повний текст джерелаXing, Shu. "Intercellular communication between bone cells induced by mechanical stimulation." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114355.
Повний текст джерелаLe chargement mécanique est crucial dans la modulation de la physiologie et de l'architecture de l'os. Des expériences antérieures ont indiqué la communication intercellulaire entre les ostéoblastes lors de la stimulation mécanique. Ces résultats suggèrent l'implication d'un médiateur soluble. L'adénosine triphosphate (ATP) extracellulaire fonctionne comme des molécules de signalisation dans de nombreux processus de régulation cellulaire. Celle-ci semble être un candidat à risque. L'ATP agit sur les ostéoblastes via les récepteurs P2. Ici, la concentration d'ATP pour chacun de ces récepteurs P2 a été modélisée mathématiquement pour mieux comprendre leur rôle. Le processus de dégradation de l'ATP et la diffusion de l'ATP, adénosine diphosphate (ADP) et adénosine monophosphate (AMP) ont aussi été modélisés. Avec le luminomètre, nous étions capables de mesurer avec succès l'ATP par dosage de la luciférase de luciole. Des images de haute résolution de la détection d'ATP ont été obtenues avec un dispositif à transfert de charge (CCD). Enfin, l'indentification locale avec une pointe de microscopie à force atomique (MFA) est appliquée mécaniquement pour stimuler un ostéoblaste. Les résultats préliminaires sur l'imagerie en temps réel de la libération d'ATP à partir d'ostéoblastes sont présentés.
Huang, Huang. "Integrin Adhesion Response to Chemical and Mechanical Stimulation." Thesis, University of Missouri - Columbia, 2019. http://pqdtopen.proquest.com/#viewpdf?dispub=13877168.
Повний текст джерелаGarnham, Carolyn Wendy. "A study of aspects of nerve stimulation with time-varying magnetic fields." Thesis, University of Sheffield, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245642.
Повний текст джерелаKhayat, Ghazaleh. "Low frequency stimulation of stem cells in dynamic culture modulates differentiation pathways." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119594.
Повний текст джерелаToutes les cellules vivantes, selon leur fonctions physiologiques, sont soumises à différentes stimulations mécaniques. L'ampleur et la fréquence de ces stimulations mécaniques varies considérablement d'un organe à un autre. Les stimulations oscillantes dues notamment à la marche, la respiration et la circulation sanguine sont largement étudiées. Par contre, les travaux concernant les stimulations a très faibles fréquences sont rare. Cette recherche examine les effets sur différents types de molécules, des stimulations mécaniques à relativement basse fréquence, à l'échelle moléculaire. Tout au long du travail présenté ici, l'accent a été mis sur la différenciation des cellules souches et la dedifférenciation des cellules primaires. Les résultats suggèrent que la pratique d'activités extrêmement lentes, à savoir les mouvements à basse fréquence, affectent, de manière significative, le mécanisme de différentiation des cellules souches. En outre, il a été constaté que les mouvements lents à la surface des cultures améliorent les caractéristiques phénotypiques des cellules primaires.
Bin, Abdulwahab Sami S. A. "The use of Functional Electrical Stimulation (FES) in maintaining or improving the ability to stand and transfer in people with Multiple Sclerosis." Thesis, University of Southampton, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316398.
Повний текст джерелаYue, Zhang. "Opto-Magneto-Electrical Nanoactuators for Wireless Cell Stimulation." Doctoral thesis, Universitat de Barcelona, 2020. http://hdl.handle.net/10803/670924.
Повний текст джерелаLos tratamientos clínicos basados en la estimulación eléctrica de células excitables han sido eficaces y ampliamente utilizados para una variedad de enfermedades. Sin embargo, estos dispositivos a menudo están limitados por su volumen, la necesidad de electrodos con cableado externo y la incapacidad de actuar en células específicas. Los dispositivos implantables que pueden convertir la energía óptica o magnética en estímulos localizados eléctricos o térmicos para activar las células, son alternativas prometedoras. Esta tesis se centró en el desarrollo de nanomateriales opto-eléctricos y magneto-opto-eléctricos para la estimulación celular inalámbrica. Actualmente, los estimuladores opto-eléctricos generalmente requieren luz visible de baja penetración y altas intensidades, y los estimuladores magnetoeléctricos generalmente proporcionan una precisión espacial y temporal deficiente. En esta tesis, se han desarrollado dos tipos de nanomateriales para superar estos desafíos. El primer nanomaterial se basó en nanopilares Si/Au para lograr la estimulación opto-eléctrica en la primera y segunda ventanas biológicas del infrarrojo cercano con intensidades de luz ultrabajas. Las simulaciones teóricas predijeron que los nanopilares de Si coronados por nanodiscos Au exhiben una mejora de 6 veces en la absorción de luz en comparación con la oblea de Si simple. Tal mejora se debe a la excitación de nuevas resonancias híbridas de metal/dieléctrico. A continuación, se presentó un exhaustivo análisis experimental opto-eléctrico-químico de los nanopilares de Si/Au. Los nanopilares cortos de Si/Au dieron el mayor rendimiento opto-eléctrico, logrando un fotovoltaje de 80 mV a una intensidad de luz ultrabaja de 0,44 µW/mm2, que fue 11 veces mayor que la oblea p-n Si simple. La fotocorriente también mostró una mejora sustancial de 2.5 veces, mostrando una combinación de corrientes capacitivas y faradaicas inducidas por la luz que pueden ajustarse con la densidad de los nanopilares Si/Au. Además, los nanopilares cortos de Si/Au mostraron una ventana de frecuencia de 50-200 Hz para maximizar la fotovoltaje y la fotocorriente. Finalmente, la biocompatibilidad de las nanoestructuras Si/Au fue validada por ensayos de viabilidad celular. El segundo nanomaterial estaba compuesto por matrices de nanocúpulas huecas de FeGa/ZnO integradas en una película elastomérica flexible y biocompatible. La estimulación magnetoeléctrica propuesta se basa en la magnetostricción del FeGa y la piezoelectricidad del ZnO. La estimulación optoeléctrica se basa en la absorción de luz infrarroja por el FeGa y la respuesta piroeléctrica del ZnO. Los resultados del comportamiento magnético revelaron que las matrices hexagonales empaquetadas con un diámetro de 400 nm proporcionaron el campo magnético de saturación más bajo y una remanencia mínima. El análisis fototérmico mostró un intenso calentamiento óptico para longitudes de onda de luz de 808 nm y 1064 nm. La biocompatibilidad se demostró evaluando la viabilidad de las células Saos-2 óseas. En conclusión, los actuadores celulares nanoestructurados de Si/Au y FeGa/ZnO constituyen nuevas plataformas para la modulación electrofisiológica inalámbrica mediante luz infrarroja y campo magnético. Mirando hacia el futuro, son prometedores como nanoactuadores inyectables e implantables in vivo debido a las posibles optimizaciones, como la fabricación en sustratos flexibles y la funcionalización de su superficie para su unión a tipos celulares específicos, que podrían ser ampliamente aplicables tanto a los estudios biológicos fundamentales como a terapias clínicas.
Valiulis, Vladas. "The effect of transcranial magnetic stimulation on brain bioelectrical activity." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140925_135043-14839.
Повний текст джерелаTranskranijinė magnetinė stimuliacija (TMS) – tai modernus neinvazinis vaistams rezistentiškų psichiatrinių sutrikimų gydymo būdas. Fiziologiniai TMS tyrimai pasižymi įvairiais, dažnai prieštaringais rezultatais, daugeliu atvejų didžiausias dėmesys skiriamas betarpiškiems poveikiams po vienos TMS procedūros, bet ne po pilno terapinio kurso. Manoma, kad rezultatų įvairovę TMS praktikoje įtakoja skirtingi stimuliacijos parametrai ir netikslumai parenkant stimuliuojamą zoną smegenyse. Nors TMS terapija dažnai traktuojama kaip švelnesnė alternatyva elektros impulsų terapijai (EIT), palyginamųjų fiziologinių šių metodikų tyrimų labai trūksta. Darbo tikslas buvo įvertinti TMS terapijos kurso poveikį bioelektriniam galvos smegenų aktyvumui ir palyginti jį su EIT terapijos poveikiu. Buvo tirta aukšto ir žemo dažnių (10 Hz ir 1 Hz) TMS terapijos įtaka EEG dažnių galios spektrui bei sukeltiniam klausos potencialui P300, naudojant standartinį ir neuronavigacinį taikinio pozicionavimą. TMS sukelti EEG pokyčiai palyginti su EIT terapijos sukeltais EEG pokyčiais, išmatuota TMS terapijos sąlygotų pokyčių dinamika kelių mėnesių bėgyje. Rezultatai parodė, kad TMS terapijos pasekoje smegenyse ryškiausiai padidėja delta dažnio galia. Naudojant standartinį pozicionavimą 10 Hz TMS sukėlė įvairesnius ir intensyvesnius EEG galios spektro pokyčius nei 1 Hz TMS. Pritaikius neuronavigacinę sistemą 10 Hz TMS atveju sumažėjo teta ir alfa dažnių galios pokyčiai. Praėjus keliems mėnesiams nuo TMS... [toliau žr. visą tekstą]
Ment, Stephanie. "Effects of seven days of continuous capacitive electrical stimulation on bone growth around titanium implants in the rat tibia." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0035/MQ64407.pdf.
Повний текст джерелаTang, Lifei. "Effects of Neuronal Nitric Oxide Synthase Signaling on Myocyte Contraction during Beta-Adrenergic Stimulation." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1385336408.
Повний текст джерелаDutta, Priyanka. "Computational Modeling of Allosteric Stimulation of Nipah Virus Host Binding Protein." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6227.
Повний текст джерелаToprani, Sheela C. "MECHANISMS OF SEIZURE REDUCTION BY LOW FREQUENCY ELECTRICAL STIMULATION." Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1399474125.
Повний текст джерелаDornan, Thomas Joseph. "Calcium Transport Inhibition, Stimulation, and Light Dependent Modulation of the Skeletal Calcium Release Channel (RyR1) by the Prototropic Forms of Pelargonidin." PDXScholar, 2014. https://pdxscholar.library.pdx.edu/open_access_etds/1931.
Повний текст джерелаYang, Yanyin. "Synthesis, characterization, microfabrication and biological applications of conducting polymers." Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1127316668.
Повний текст джерелаTitle from first page of PDF file. Document formatted into pages; contains xv, 192 p.; also includes graphics (some col.). Includes bibliographical references (p. 183-192). Available online via OhioLINK's ETD Center
Valiulis, Vladas. "Transkranijinės magnetinės stimuliacijos įtaka galvos smegenų bioelektriniam aktyvumui." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140925_135031-16126.
Повний текст джерелаTranscranial magnetic stimulation (TMS) is a modern non invasive method of drug resistant psychiatric disorder treatment. TMS physiology research is hindered by variable, often controversial results. In most studies main attention is being focused on immediate effects after single TMS procedure rather than the influence of a complete therapy course. It is considered that variability of results in TMS practice is caused by different stimulation parameters and imprecision of stimulated area placement in the brain. Although TMS therapy is often viewed as a milder alternative to electroconvulsive therapy (ECT), comparative physiological studies of these two methods are very rare. The aim of this study was to evaluate the effect of rTMS therapy course on bioelectrical brain activity and compare it to an ECT effect. Research included the effect of high and low frequency (10 Hz and 1 Hz) TMS on EEG band power spectrum and auditory evoked potential P300, using both standard and neuronavigated target positioning. TMS evoked EEG changes were also compared to the changes of ECT. Change dynamics after several months of TMS therapy were also measured. Results showed that after TMS therapy the most notable change in the brain occurs in the form of delta power increase. When using standard positioning 10 Hz TMS evokes more diverse and intense EEG band power spectrum changes than the 1 Hz TMS. Application of neuronavigation system decreases theta and alpha band power changes in 10 Hz TMS... [to full text]
Taghian, Toloo. "Interaction of an Electric Field with Vascular Cells." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1439309071.
Повний текст джерелаMichel, Christophe. "Modélisation mathématique de l'activité électrophysiologique des neurones auditifs primaires." Phd thesis, Université Montpellier II - Sciences et Techniques du Languedoc, 2012. http://tel.archives-ouvertes.fr/tel-00808610.
Повний текст джерела"Augmentation of the osteotendinous junctional healing by biophysical stimulations: a partial patellectomy model in rabbits." Thesis, 2006. http://library.cuhk.edu.hk/record=b6074236.
Повний текст джерелаLIPUS is a "non-contact" biomechanical stimulation, which can provide a direct mechanical stimulation through cavitation and acoustic microstreaming effects to improve tissue healing in a less-than-rigid biomechanical environment. So the mechanical stimulation induced from LIPUS could be applied immediately after surgery without worrying about the mechanical strain exceed the structural property at the osteotendinous healing interface in the early phase of repair. In this part of study, we also examined the effects of the regime of biomechanical stimulations applying immediately after repair on the osteotendinous healing interface. By using the same healing junction model, forty-two female New Zealand white rabbits were randomly divided into two groups; daily mechanical stimulation was applied immediately after surgery lasting up to post-operative 12 weeks on the healing interface in the treatment group. The regime of mechanical stimulations included by LIPUS was 20 minutes, 5 days per week for 4 weeks, followed by cyclic mechanical stimulation generated from quadriceps muscles induced by FES for 8 weeks. Results showed that early application of biomechanical stimulations on the osteotendinous healing interface were significantly better radiologically, histologically and biomechanically than that of not any or later application of the biomechanical stimulations during the osteotendinous healing processes when assessing at the same healing time point. In addition, the early application of biomechanical stimulations showed the better functional recovery in terms of the restoration of the proprioceptions, which an increased numbers of sensory nerve endings labeled by calcitonin gene-relate peptide (CGRP) was detected in the whole osteotendinous healing complex.
Sports or trauma injuries around osteotendinous junctions are common; treatments usually require surgical reattachment of the involved tendon to bone. Restoration of osteotendinous junction after repair is slow and difficult due to regenerating the intermitted fibrocartilage zone to connect two different characteristic tissues, tendon to bone. Although the factors influencing fibrocartilage zone regeneration and remodeling during osteotendinous repair are poorly understood, however, is believed that the mechanical environment plays an important role in such healing process. In present study, the effects of mechanical stimulation on osteotendinous healing process were examined, in the way of mechanical stimulations induced by biophysical stimulations, surface functional electric stimulation (FES) and low intensity pulsed ultrasound (LIPUS), applying on the patellar tendon to patellar bone healing interface in an established partial patellectomy model in rabbits.
The mechanotransductive stimulation linked to the transmission of forces across osteotendinous junction can be generated from its muscle contraction induced by FES. In the partial patellectomy model, thirty-five female New Zealand white rabbits were randomly divided into two groups with initial immobilization for 6 weeks, daily FES was applied to quadriceps muscles for 30 minutes, 5 days per week for 6 weeks in treatment group and compared with non-treatment control group at postoperative week 6, 12 and 18, radiologically, histologically and biomechanically. Results showed that FES-induced cyclic mechanical stimulation significantly increased new bone formation and its bone mineral density. An elevated expression of tenascin C and TGFbeta1; an increased proteoglycant stainability; mature fibrocartilage zone formation with better resumptions of biomechanical properties also observed on the osteotendinous healing interface, indicating that the post-operative programmed cyclic mechanical stimulation generated from its muscle contraction has beneficial effects on osteotendinous healing processes by facilitating the fibrocartilagious transitional zone regeneration.
by Wang Wen.
Advisers: Kai Ming Chan; Ling Qin.
Source: Dissertation Abstracts International, Volume: 68-03, Section: B, page: 1550.
Thesis (Ph.D.)--Chinese University of Hong Kong, 2006.
Includes bibliographical references (p. 159-175).
Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.
Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web.
Abstracts in English and Chinese.
School code: 1307.
Biela, Sarah A. [Verfasser]. "Stimulation of vascular cells by extracellular signals : a biophysical analysis / put forward by Sarah A. Biela." 2009. http://d-nb.info/99578826X/34.
Повний текст джерелаMencarelli, Lucia. "Non-invasive brain stimulation in humans: from image-guided targeting to clinical application." Doctoral thesis, 2021. http://hdl.handle.net/2158/1238666.
Повний текст джерелаPanda, Asish Kumar. "Directing cellular differentiation using biophysical cues on multifunctional biomaterial platforms for neural and osteochondral applications." Thesis, 2021. https://etd.iisc.ac.in/handle/2005/5572.
Повний текст джерелаΠαπαδόπουλος, Βασίλειος Γ. "Η συμβολή του ακουστικού ερεθισμού στη μελέτη της βιοφυσικής κατάστασης του εμβρύου κατά το 3ο τρίμηνο της κύησης". Thesis, 2006. http://nemertes.lis.upatras.gr/jspui/handle/10889/1386.
Повний текст джерелаOBJECTIVES: To verify the effect of vibroacoustic stimulation on biophysical profile score, with a prospective randomised study. STUDY DESIGN: All women with singleton pregnancy, gestational age ≥ 30 weeks, intact membranes and biophysical profile score ≤ 8/10 entered the study, after giving written consent, and were randomised to two groups. In group A, a 3-second stimulus with an artificial larynx was applied; if biophysical profile remained abnormal for 30 minutes, a second stimulus was applied, and it was assessed again. In group B the observation time was extended for 60 minutes to match the time periods of group A. Pregnancies were managed by final test score and patients delivering more than 24 hours apart from last examination were disregarded from the study. Outcome criteria were intrauterine deaths, caesarean sections for fetal distress, Apgar score < 7 at 5 minutes postpartum, meconium-stained amniotic fluid and neonatal intensive care unit admissions. Our null hypothesis was that application of vibroacoustic stimulation does not alter test’s statistical parameters. RESULTS: 1,349 patients were randomised in group A, and 1,484 in group B (2,833 in total). When comparing group A to B, application of vibroacoustic stimulation significantly decreased the number of positive tests (4.74% vs. 6.67%, p < 0.05) and increased the prevalence of outcome criteria in this subgroup (positive likelihood ratio: 24.1-CI 95%: 11.12-52.46 vs. 7.52-CI 95%: 4.93-11.46), without altering perinatal outcome. Furthermore, specificity, positive predictive value and test accuracy were significantly improved, as well as negative predictive value for intrauterine death. CONCLUSION: Vibroacoustic stimulation improves the efficiency of biophysical profile score by decreasing false positive tests and improving test accuracy and should be considered as a means of a more thorough fetal evaluation when fetal compromise is suspected.
"The regulation of gene expression by mechanical stimulation and parathyroid hormone in bone in vivo." Tulane University, 1996.
Знайти повний текст джерелаacase@tulane.edu
MAGGIO, FERNANDO. "Stimolazione elettrica e magnetica del sistema nervoso: studi teorici e sviluppo terapeutico." Doctoral thesis, 2011. http://hdl.handle.net/11573/918072.
Повний текст джерелаMAGGIO, FERNANDO. "Stimolazione elettrica e magnetica del sistema nervoso: studi teorici e sviluppo terapeutico." Doctoral thesis, 2011. http://hdl.handle.net/11573/918168.
Повний текст джерела