Дисертації з теми "Biophysical characterisation"
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Sarkar, Supti. "Biophysical characterisation of plasmid formulation." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1446862/.
Повний текст джерелаDamianoglou, Angeliki. "Biophysical characterisation of peptides and proteins." Thesis, University of Warwick, 2010. http://wrap.warwick.ac.uk/3664/.
Повний текст джерелаVenkatesan, Meenakshi. "Biophysical characterisation of PAK/Cdc42 interaction." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620265.
Повний текст джерелаTsytlonok, Maksym. "Biophysical characterisation of linear repeat proteins." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610764.
Повний текст джерелаHerbert, Andrew Peter. "Biophysical characterisation of measles virus receptors." Thesis, University of Edinburgh, 2002. http://hdl.handle.net/1842/15013.
Повний текст джерелаTully, Mark David. "Biophysical characterisation of SAP97 and AKAP79." Thesis, University of Liverpool, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.548812.
Повний текст джерелаClewes, Oliver. "Recombinant proneurotrophins : production, purification and biophysical characterisation." Thesis, University of Bristol, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.443699.
Повний текст джерелаPhilippe, Didier. "Biophysical characterisation of 'Staphylococcus aureus' defence proteins." Thesis, University of Bath, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426285.
Повний текст джерелаChen, Ho Ann. "Biophysical characterisation of rat CD2 domain 1." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392332.
Повний текст джерелаHarvey, Richard Douglas. "Biophysical characterisation of vesicles containing nonionic surfactants." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396320.
Повний текст джерелаSklepari, Meropi. "Stability and biophysical characterisation of protein therapeutics." Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/98558/.
Повний текст джерелаKearney, Alice. "Biophysical characterisation of interactions involving CD2 family members." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437361.
Повний текст джерелаBrown, Peter N. "Biophysical and structural characterisation of protein-peptide interactions." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/3982.
Повний текст джерелаFairweather, Victoria S. S. "Biophysical characterisation of DNA-binding proteins and oxidoreductases." Thesis, University of Bristol, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508074.
Повний текст джерелаAng, H. C. "Biophysical characterisation and rescue of p53 cancer mutants." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596120.
Повний текст джерелаBaldwin, Andrew Keith. "Biophysical characterisation of a liposomal gene delivery system." Thesis, University of Nottingham, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405147.
Повний текст джерелаHanlon, Michael Richard. "Molecular modelling and biophysical characterisation of three proteins." Thesis, Birkbeck (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326154.
Повний текст джерелаHussain, F. "The biochemical and biophysical characterisation of p47phox activation." Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/1444240/.
Повний текст джерелаDobson, John Andrew. "Biophysical characterisation of biopharmaceuticals under defined flow fields." Thesis, University of Leeds, 2017. http://etheses.whiterose.ac.uk/20779/.
Повний текст джерелаMortuza, Gulnahar B. "Cytochrome bâ‚… : biophysical characterisation of a haem binding protein." Thesis, Queen Mary, University of London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312882.
Повний текст джерелаMohammed, Diar. "Biophysical characterisation of the skin at a molecular level." Thesis, University College London (University of London), 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.579673.
Повний текст джерелаSpencer, Kelly-Anne. "Biophysical characterisation of the infectious bronchitis virus nucleocapsid protein." Thesis, University of Leeds, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436017.
Повний текст джерелаSaul, Louise. "Biophysical characterisation of the Cannabinoid Receptor interacting protein CRIP1a." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/biophysical-characterisation-of-the-cannabinoid-receptor-interacting-protein-crip1a(45acbe47-1468-45f3-afbc-2ee6b8078cec).html.
Повний текст джерелаJohansson, Conny M. "Biophysical characterisation of the hepatocyte growth factor-glycosaminoglycan interaction." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/9904.
Повний текст джерелаJutton, Mark Robert. "Biophysical and biological characterisation of a soluble human CD23 pigment." Thesis, King's College London (University of London), 2007. https://kclpure.kcl.ac.uk/portal/en/theses/biophysical-and-biological-characterisation-of-a-soluble-human-cd23-pigment(4a13a8ad-ea7a-4ba1-877d-ddd3811786a6).html.
Повний текст джерела林志明 and Chi-ming Lam. "Characterisation of the biophysical and pathophysiological effects of hepatic cryosurgery." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1996. http://hub.hku.hk/bib/B31979580.
Повний текст джерелаStreeter, Simon David. "Biochemical and biophysical characterisation of the gene regulatory protein C.AhdI." Thesis, University of Portsmouth, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402283.
Повний текст джерелаSchlegel, K. "Next generation biosensors for biophysical characterisation and detection of viruses." Thesis, University College London (University of London), 2016. http://discovery.ucl.ac.uk/1492686/.
Повний текст джерелаChamberlain, Jonathan Michael Garrard. "Biophysical characterisation of the serum amyloid P component-DNA interaction." Thesis, University of Portsmouth, 2016. https://researchportal.port.ac.uk/portal/en/theses/biophysical-characterisation-of-the-serum-amyloid-p-component--dna-interaction(992877ff-9c22-4fab-9e29-b88dda3dff1b).html.
Повний текст джерелаDaga, Sunil Kumar Omprakash. "Biophysical characterisation and profile of HLA-specific antibodies in transplantation." Thesis, University of Warwick, 2015. http://wrap.warwick.ac.uk/70964/.
Повний текст джерелаLam, Chi-ming. "Characterisation of the biophysical and pathophysiological effects of hepatic cryosurgery." Hong Kong : University of Hong Kong, 1996. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19712091.
Повний текст джерелаHenning, Karen. "Structural, biochemical and biophysical characterisation of human transcription factor RBP-Jκ". Diss., lmu, 2006. http://nbn-resolving.de/urn:nbn:de:bvb:19-59860.
Повний текст джерелаGretton, Sarah N. "Topology and biophysical characterisation of the hepatitis C virus NS4B protein." Thesis, University of Glasgow, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433078.
Повний текст джерелаFung, Kar Ho Herman. "Biophysical and structural characterisation of the bacteriophage HK97 DNA packaging system." Thesis, University of York, 2017. http://etheses.whiterose.ac.uk/19153/.
Повний текст джерелаYang, Su jeong. "Biochemical and biophysical characterisation of allelic variants of ovine prion protein." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611255.
Повний текст джерелаMichalke, Kerstin. "Expression, purification and biophysical characterisation of mammalian GPCRs for structural studies." Aix-Marseille 1, 2008. http://www.theses.fr/2008AIX11018.
Повний текст джерелаG protein–coupled receptors represent the largest family of eukaryotic transmembrane signal transduction proteins. Because of their central role in the body, GPCRs are linked to many human diseases and are therefore important targets for therapeutics. The knowledge of high resolution x-ray structures for GPCRs would facilitate the development of those therapeutics. However, because of their hydrophobic nature and their low abundance in the body, only a few GPCR x-ray structures are known. Within the project MePNet, we therefore produced and characterised GPCRs to subject them to cristallisation assays. We have expressed 45 out of 100 GPCRs in inclusion bodies, almost the half of them with high yields. Expression is neither dependent on the expression temperature nor the cystein content nor the size of individual receptors. Gateway vectors appeared to be superiour to pET vectors and C43 proved to be the most successful expression strain. Expression was successfully scaled up in flasks and fermentors. Fermentor expressed huPTH1R and muCB1R were solubilised in SDS and refolded by artificial chaperone assisted refolding, yielding 280mg and 370mg of refolded PTH1R and CB1R per litre fermentor culture, respectively. Native receptor folding was verified by binding tests. For PTH1R/PTH(1-34) interaction a Kd of 6,5 nM was measured by BIAcore and 56 nM by tryptophan fluorescence quenching assay. CB1R showed an affinity of 38,2 nM for inverse agonist [3H]SR141716A and 19,4 nM for agonist [3H]CP 55,940 in the radioligand binding assay. The CB1R preparation contained 30% of active receptor. Analytic SEC coupled to LS/UV/RI detectors showed that the receptor preparations were contaminated with aggregates, which could be reduced by ultracentrifugation and ligand affinity chromatography, and by changing refolding and gelfiltration conditions. PTH1R and CB1R specific camel heavy chain antibodies fragments (vHHs) were generated and characterised by BIAcore. All tested fragments showed receptor binding activities in the nanomolar range (12- 70nM). Epitopes of PTH1R specific vHHs seem neither to overlap one another nor the binding site of ligand PTH (1-34), which might allow the usage of PTH1R/ PTH (1-34)/ vHH complexes with more than one vHH in crystallisation. PTH1R and CB1R were tested in up to 1400 crystallisation condition, none of these leading to the formation of crystals
Widdowson, Philip. "Biochemical and biophysical characterisation of Anopheles gambiae NADPH-cytochrome P450 reductase." Thesis, University of Liverpool, 2010. http://livrepository.liverpool.ac.uk/1496/.
Повний текст джерелаLappin, Sarah Crawford. "Biophysical and pharmacological characterisation of recombinant and native rat P2X7 receptors." Thesis, Imperial College London, 2009. http://hdl.handle.net/10044/1/4360.
Повний текст джерелаO'Brien, Fiona Margaret. "Biophysical characterisation of the mechanisms regulating sarcoplasmic reticulum K+ channel gating." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:17e51bc1-5b1f-4b52-8e46-98c888a91e00.
Повний текст джерелаHuang, Hai. "Biophysical Characterisation of Two Mutations Causing Long QT Syndrome and Brugada Syndrome." Thesis, Université Laval, 2006. http://www.theses.ulaval.ca/2006/23724/23724.pdf.
Повний текст джерелаBrazer, Stephen Paul. "Structural characterisation of recombinant and synthetic proteins and peptides by biophysical techniques." Thesis, University College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285159.
Повний текст джерелаMurton, Ben Lewis. "A biophysical characterisation of the complex of proteins associated with Set1 (COMPASS)." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611449.
Повний текст джерелаMartino, Angela. "A new serogroup B meningococcal vaccine : biophysical characterisation of its protein components." Thesis, University of Warwick, 2013. http://wrap.warwick.ac.uk/59409/.
Повний текст джерелаOno, Shusuke. "The biophysical characterisation of the Enterobacterial nucleoid proteins H-NS and StpA." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1445757/.
Повний текст джерелаMcDevitt, Christopher A. "The molecular analysis and biophysical characterisation of DMS dehydrogenase from Rhodovulum sulfidophilum /." St. Lucia, Qld, 2002. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16102.pdf.
Повний текст джерелаLehner, Ines [Verfasser]. "Biophysical and biochemical characterisation of the SMR proteins Hsmr and EmrE / Ines Lehner." Frankfurt : Universitätsbibliothek Frankfurt am Main, 2011. http://d-nb.info/1011595397/34.
Повний текст джерелаBullard, Desmond. "The biochemical and biophysical characterisation of DNA and RNA ligases from bacteriophage T4." Thesis, University of East Anglia, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441566.
Повний текст джерелаFox, Daniel George. "Expression and biophysical characterisation of the domains of the Pf1 gene 5 protein." Thesis, University of Portsmouth, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386252.
Повний текст джерелаDioletis, E. "Biochemical and biophysical characterisation of the death domain of death associated protein kinase." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1338144/.
Повний текст джерелаRabu, Amir. "Biochemical and biophysical characterisation of heat shock protein 90 and its domain interactions." Thesis, University of Edinburgh, 2006. http://hdl.handle.net/1842/11286.
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