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Статті в журналах з теми "Biophotonic fiber"

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Автор: Grafiati

Опубліковано: 7 липня 2024

Оновлено: 7 липня 2024

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1

Kang, Taeyoung, Yongjun Cho, Kyeong Min Yuk, Chan Yeong Yu, Seung Ho Choi, and Kyung Min Byun. "Fabrication and Characterization of Novel Silk Fiber-Optic SERS Sensor with Uniform Assembly of Gold Nanoparticles." Sensors 22, no. 22 (November 21, 2022): 9012. http://dx.doi.org/10.3390/s22229012.

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Biocompatible optical fibers and waveguides are gaining attention as promising platforms for implantable biophotonic devices. Recently, the distinct properties of silk fibroin were extensively explored because of its unique advantages, including flexibility, process compatibility, long-term biosafety, and controllable biodegradability for in vitro and in vivo biomedical applications. In this study, we developed a novel silk fiber for a sensitive optical sensor based on surface-enhanced Raman spectroscopy (SERS). In contrast to conventional plasmonic nanostructures, which employ expensive and time-consuming fabrication processes, gold nanoparticles were uniformly patterned on the top surface of the fiber employing a simple and cost-effective convective self-assembly technique. The fabricated silk fiber-optic SERS probe presented a good performance in terms of detection limit, sensitivity, and linearity. In particular, the uniform pattern of gold nanoparticles contributed to a highly linear sensing feature compared to the commercial multi-mode fiber sample with an irregular and aggregated distribution of gold nanoparticles. Through further optimization, silk-based fiber-optic probes can function as useful tools for highly sensitive, cost-effective, and easily tailored biophotonic platforms, thereby offering new capabilities for future implantable SERS devices.

2

Taylor, James R. "Tutorial on fiber-based sources for biophotonic applications." Journal of Biomedical Optics 21, no. 6 (June 10, 2016): 061010. http://dx.doi.org/10.1117/1.jbo.21.6.061010.

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3

Monti, Tamara, and Gabriele Gradoni. "Hollow-Core Coaxial Fiber Sensor for Biophotonic Detection." IEEE Journal of Selected Topics in Quantum Electronics 20, no. 2 (March 2014): 134–42. http://dx.doi.org/10.1109/jstqe.2013.2280497.

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4

Runcorn, Timothy H., Frederik G. Gorlitz, Robert T. Murray, and Edmund J. R. Kelleher. "Visible Raman-Shifted Fiber Lasers for Biophotonic Applications." IEEE Journal of Selected Topics in Quantum Electronics 24, no. 3 (May 2018): 1–8. http://dx.doi.org/10.1109/jstqe.2017.2770101.

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5

Pallarés-Aldeiturriaga, David, Pablo Roldán-Varona, Luis Rodríguez-Cobo, and José Miguel López-Higuera. "Optical Fiber Sensors by Direct Laser Processing: A Review." Sensors 20, no. 23 (December 6, 2020): 6971. http://dx.doi.org/10.3390/s20236971.

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The consolidation of laser micro/nano processing technologies has led to a continuous increase in the complexity of optical fiber sensors. This new avenue offers novel possibilities for advanced sensing in a wide set of application sectors and, especially in the industrial and medical fields. In this review, the most important transducing structures carried out by laser processing in optical fiber are shown. The work covers different types of fiber Bragg gratings with an emphasis in the direct-write technique and their most interesting inscription configurations. Along with gratings, cladding waveguide structures in optical fibers have reached notable importance in the development of new optical fiber transducers. That is why a detailed study is made of the different laser inscription configurations that can be adopted, as well as their current applications. Microcavities manufactured in optical fibers can be used as both optical transducer and hybrid structure to reach advanced soft-matter optical sensing approaches based on optofluidic concepts. These in-fiber cavities manufactured by femtosecond laser irradiation followed by chemical etching are promising tools for biophotonic devices. Finally, the enhanced Rayleigh backscattering fibers by femtosecond laser dots inscription are also discussed, as a consequence of the new sensing possibilities they enable.

6

Tseng, Sheng-Hao, Tzu-Feng Huang, Jun-Liang Yeh, and Ming-Che Chan. "Signal Enhancement by Fiber-Dispersion in Sub-GHz Frequency Domain Biophotonic Diagnosis Systems." IEEE Journal of Selected Topics in Quantum Electronics 25, no. 1 (January 2019): 1–7. http://dx.doi.org/10.1109/jstqe.2018.2846054.

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7

Hurot, Charlotte, Wan Zakiah Wan Ismail, and Judith M. Dawes. "Random laser in a fiber: combined effects of guiding and scattering lead to a reduction of the emission threshold." Optical Data Processing and Storage 3, no. 1 (September 26, 2017): 97–100. http://dx.doi.org/10.1515/odps-2017-0012.

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Abstract Random fiber lasers incorporate scattering particles with optical gain in a fiber geometry and offer potential for sensing and biophotonics applications. In this work, the combined effects of waveguiding and scattering in random fiber lasers were investigated. A dye solution with nanoparticles was inffltrated into the hollow core of the microstructured optical fibers and the fibers were side pumped by a frequency-doubled Nd:YAG laser. The resulting emission threshold was reduced in comparison with the bulk solution.We used a Matlab model to gain a better understanding of the competing feedback mechanisms involved.

8

Månefjord, Hampus, Meng Li, Christian Brackmann, Nina Reistad, Anna Runemark, Jadranka Rota, Benjamin Anderson, Jeremie T. Zoueu, Aboma Merdasa, and Mikkel Brydegaard. "A biophotonic platform for quantitative analysis in the spatial, spectral, polarimetric, and goniometric domains." Review of Scientific Instruments 93, no. 11 (November 1, 2022): 113709. http://dx.doi.org/10.1063/5.0095133.

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Advanced instrumentation and versatile setups are needed for understanding light interaction with biological targets. Such instruments include (1) microscopes and 3D scanners for detailed spatial analysis, (2) spectral instruments for deducing molecular composition, (3) polarimeters for assessing structural properties, and (4) goniometers probing the scattering phase function of, e.g., tissue slabs. While a large selection of commercial biophotonic instruments and laboratory equipment are available, they are often bulky and expensive. Therefore, they remain inaccessible for secondary education, hobbyists, and research groups in low-income countries. This lack of equipment impedes hands-on proficiency with basic biophotonic principles and the ability to solve local problems with applied physics. We have designed, prototyped, and evaluated the low-cost Biophotonics, Imaging, Optical, Spectral, Polarimetric, Angular, and Compact Equipment (BIOSPACE) for high-quality quantitative analysis. BIOSPACE uses multiplexed light-emitting diodes with emission wavelengths from ultraviolet to near-infrared, captured by a synchronized camera. The angles of the light source, the target, and the polarization filters are automated by low-cost mechanics and a microcomputer. This enables multi-dimensional scatter analysis of centimeter-sized biological targets. We present the construction, calibration, and evaluation of BIOSPACE. The diverse functions of BIOSPACE include small animal spectral imaging, measuring the nanometer thickness of a bark-beetle wing, acquiring the scattering phase function of a blood smear and estimating the anisotropic scattering and the extinction coefficients, and contrasting muscle fibers using polarization. We provide blueprints, component list, and software for replication by enthusiasts and educators to simplify the hands-on investigation of fundamental optical properties in biological samples.

9

Novta, Evgenije, Tijana Lainovic, Dusan Grujic, Jelena Komsic, Dejan Pantelic, and Larisa Blazic. "Novel biophotonics-based techniques in dental medicine - a literature review." Medical review 73, no. 11-12 (2020): 364–68. http://dx.doi.org/10.2298/mpns2012364n.

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Introduction. Biophotonics deals with interactions between light and biological matter, integrating knowledge of physics, chemistry, engineering, biology, and medicine for solving specific biomedical or life science problems. Due to the ability to provide non-invasive, highly sensitive tissue information and inducing specific localized tissue ablation, biophotonics-based technologies may be of utmost importance in improving dental healthcare. The aim of this review article is to give an overview of contemporary biophotonics-based technologies and their applications in dental research and clinical practice. Various applications of biophotonics-based technologies. Biomedical imaging techniques (nonlinear microscopy methods and optical coherence tomography), photo-mechanical methods (digital holographic interferometry, photo-elasticity, digital image correlation, Moir? interferometry), optical spectroscopy techniques (Raman and Fourier transform infrared spectroscopy, Brillouin light scattering spectroscopy), fiber Bragg grating sensors, photodynamic therapy, photo-biostimulation, and femtosecond laser applications are presented in this paper. Conclusion. In accordance with the modern tendencies of prevention and timely diagnosis of oral diseases, biophotonics may be considered the leading scientific discipline on the path of progress of dental medicine and technology. Therefore, this paper provides an overview of modern methods based on biophotonics and summarizes their applicability focusing on the field of dental medicine.

10

Tu, Haohua, and Stephen A. Boppart. "Coherent fiber supercontinuum for biophotonics." Laser & Photonics Reviews 7, no. 5 (July 23, 2012): 628–45. http://dx.doi.org/10.1002/lpor.201200014.

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11

Rahmani, Babak, Ilker Oguz, Ugur Tegin, Jih-liang Hsieh, Demetri Psaltis, and Christophe Moser. "Learning to image and compute with multimode optical fibers." Nanophotonics 11, no. 6 (January 21, 2022): 1071–82. http://dx.doi.org/10.1515/nanoph-2021-0601.

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Abstract Multimode fibers (MMF) were initially developed to transmit digital information encoded in the time domain. There were few attempts in the late 60s and 70s to transmit analog images through MMF. With the availability of digital spatial modulators, practical image transfer through MMFs has the potential to revolutionize medical endoscopy. Because of the fiber’s ability to transmit multiple spatial modes of light simultaneously, MMFs could, in principle, replace the millimeters-thick bundles of fibers currently used in endoscopes with a single fiber, only a few hundred microns thick. That, in turn, could potentially open up new, less invasive forms of endoscopy to perform high-resolution imaging of tissues out of reach of current conventional endoscopes. Taking endoscopy by its general meaning as looking into, we review in this paper novel ways of imaging and transmitting images using a machine learning approach. Additionally, we review recent work on using MMF to perform machine learning tasks. The advantages and disadvantages of using machine learning instead of conventional methods is also discussed. Methods of imaging in scattering media and particularly MMFs involves measuring the phase and amplitude of the electromagnetic wave, coming out of the MMF and using these measurements to infer the relationship between the input and the output of the MMF. Most notable techniques include analog phase conjugation [A. Yariv, “On transmission and recovery of three-dimensional image information in optical waveguides,” J. Opt. Soc. Am., vol. 66, no. 4, pp. 301–306, 1976; A. Gover, C. Lee, and A. Yariv, “Direct transmission of pictorial information in multimode optical fibers,” J. Opt. Soc. Am., vol. 66, no. 4, pp. 306–311, 1976; G. J. Dunning and R. Lind, “Demonstration of image transmission through fibers by optical phase conjugation,” Opt. Lett., vol. 7, no. 11, pp. 558–560, 1982; A. Friesem, U. Levy, and Y. Silberberg, “Parallel transmission of images through single optical fibers,” Proc. IEEE, vol. 71, no. 2, pp. 208–221, 1983], digital phase conjugation [I. N. Papadopoulos, S. Farahi, C. Moser, and D. Psaltis, “Focusing and scanning light through a multimode optical fiber using digital phase conjugation,” Opt. Express, vol. 20, no. 10, pp. 10583–10590, 2012; I. N. Papadopoulos, S. Farahi, C. Moser, and D. Psaltis, “High-resolution, lensless endoscope based on digital scanning through a multimode optical fiber,” Biomed. Opt. Express, vol. 4, no. 2, pp. 260–270, 2013] or the full-wave holographic transmission matrix method. The latter technique, which is the current gold standard, measures both the amplitude and phase of the output patterns corresponding to multiple input patterns to construct a matrix of complex numbers relaying the input to the output [Y. Choi, et al., “Scanner-free and wide-field endoscopic imaging by using a single multimode optical fiber,” Phys. Rev. Lett., vol. 109, no. 20, p. 203901, 2012; A. M. Caravaca-Aguirre, E. Niv, D. B. Conkey, and R. Piestun, “Real-time resilient focusing through a bending multimode fiber,” Opt. Express, vol. 21, no. 10, pp. 12881–12887; R. Y. Gu, R. N. Mahalati, and J. M. Kahn, “Design of flexible multi-mode fiber endoscope,” Opt. Express, vol. 23, no. 21, pp. 26905–26918, 2015; D. Loterie, S. Farahi, I. Papadopoulos, A. Goy, D. Psaltis, and C. Moser, “Digital confocal microscopy through a multimode fiber,” Opt. Express, vol. 23, no. 18, pp. 23845–23858, 2015]. This matrix is then used for imaging of the inputs or projection of desired patterns. Other techniques rely on iteratively optimizing the pixel value of the input image to perform a particular task (such as focusing or displaying an image) [R. Di Leonardo and S. Bianchi, “Hologram transmission through multi-mode optical fibers,” Opt. Express, vol. 19, no. 1, pp. 247–254, 2011; T. Čižmár and K. Dholakia, “Shaping the light transmission through a multimode optical fibre: complex transformation analysis and applications in biophotonics,” Opt. Express, vol. 19, no. 20, pp. 18871–18884, 2011; T. Čižmár and K. Dholakia, “Exploiting multimode waveguides for pure fibre-based imaging,” Nat. Commun., vol. 3, no. 1, pp. 1–9, 2012; S. Bianchi and R. Di Leonardo, “A multi-mode fiber probe for holographic micromanipulation and microscopy,” Lab Chip, vol. 12, no. 3, pp. 635–639, 2012; E. R. Andresen, G. Bouwmans, S. Monneret, and H. Rigneault, “Toward endoscopes with no distal optics: video-rate scanning microscopy through a fiber bundle,” Opt. Lett., vol. 38, no. 5, pp. 609–611, 2013].

12

Ke Wang, Nicholas G. Horton, Kriti Charan, and Chris Xu. "Advanced Fiber Soliton Sources for Nonlinear Deep Tissue Imaging in Biophotonics." IEEE Journal of Selected Topics in Quantum Electronics 20, no. 2 (March 2014): 50–60. http://dx.doi.org/10.1109/jstqe.2013.2276860.

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13

Saltarelli, Francesco, Vikas Kumar, Daniele Viola, Francesco Crisafi, Fabrizio Preda, Giulio Cerullo, and Dario Polli. "Photonic Time-Stretch Spectroscopy for Multiplex Stimulated Raman Scattering." EPJ Web of Conferences 205 (2019): 03003. http://dx.doi.org/10.1051/epjconf/201920503003.

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Stimulated Raman scattering spectroscopy enables label-free molecular identification, but its broadband implementation is technically challenging. We experimentally demonstrate a novel approach to multiplex stimulated Raman scattering based on photonic time stretch. A telecom fiber stretches the broadband femtosecond Stokes pulse after the sample to ∼15ns, mapping its spectrum in time. The signal is sampled through a fast oscilloscope, providing single-shot spectra at 80-kHz rate. We demonstrate high sensitivity in detecting the Raman vibrational modes of various samples over the entire high-frequency C-H stretching region. Our results pave the way to high-speed broadband vibrational imaging for materials science and biophotonics.

14

Ermatov, Timur, Julia S. Skibina, Valery V. Tuchin, and Dmitry A. Gorin. "Functionalized Microstructured Optical Fibers: Materials, Methods, Applications." Materials 13, no. 4 (February 19, 2020): 921. http://dx.doi.org/10.3390/ma13040921.

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Microstructured optical fiber-based sensors (MOF) have been widely developed finding numerous applications in various fields of photonics, biotechnology, and medicine. High sensitivity to the refractive index variation, arising from the strong interaction between a guided mode and an analyte in the test, makes MOF-based sensors ideal candidates for chemical and biochemical analysis of solutions with small volume and low concentration. Here, we review the modern techniques used for the modification of the fiber’s structure, which leads to an enhanced detection sensitivity, as well as the surface functionalization processes used for selective adsorption of target molecules. Novel functionalized MOF-based devices possessing these unique properties, emphasize the potential applications for fiber optics in the field of modern biophotonics, such as remote sensing, thermography, refractometric measurements of biological liquids, detection of cancer proteins, and concentration analysis. In this work, we discuss the approaches used for the functionalization of MOFs, with a focus on potential applications of the produced structures.

15

Lee, Gi Hyen, Soyeon Ahn, Min Su Kim, Sang Won Lee, Ji Su Kim, Byeong Kwon Choi, Srinivas Pagidi, and Min Yong Jeon. "Output Characterization of 220 nm Broadband 1250 nm Wavelength-Swept Laser for Dynamic Optical Fiber Sensors." Sensors 22, no. 22 (November 16, 2022): 8867. http://dx.doi.org/10.3390/s22228867.

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Broadband wavelength-swept lasers (WSLs) are widely used as light sources in biophotonics and optical fiber sensors. Herein, we present a polygonal mirror scanning wavelength filter (PMSWF)-based broadband WSL using two semiconductor optical amplifiers (SOAs) with different center wavelengths as the gain medium. The 10-dB bandwidth of the wavelength scanning range with 3.6 kHz scanning frequency was approximately 223 nm, from 1129 nm to 1352 nm. When the scanning frequency of the WSL was increased, the intensity and bandwidth decreased. The main reason for this is that the laser oscillation time becomes insufficient as the scanning frequency increases. We analyzed the intensity and bandwidth decrease according to the increase in the scanning frequency in the WSL through the concept of saturation limit frequency. In addition, optical alignment is important for realizing broadband WSLs. The optimal condition can be determined by analyzing the beam alignment according to the position of the diffraction grating and the lenses in the PMSWF. This broadband WSL is specially expected to be used as a light source in broadband distributed dynamic FBG fiber-optic sensors.

16

Xiaomin Liu, J. Lagsgaard, and D. Turchinovich. "Monolithic Highly Stable Yb-Doped Femtosecond Fiber Lasers for Applications in Practical Biophotonics." IEEE Journal of Selected Topics in Quantum Electronics 18, no. 4 (July 2012): 1439–50. http://dx.doi.org/10.1109/jstqe.2012.2183580.

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17

Kim, Do-Hyun, Ilko K. Ilev, and Jin U. Kang. "Fiberoptic Confocal Microscopy Using a 1.55-$\mu$m Fiber Laser for Multimodal Biophotonics Applications." IEEE Journal of Selected Topics in Quantum Electronics 14, no. 1 (2008): 82–87. http://dx.doi.org/10.1109/jstqe.2007.914589.

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18

Myndrul, Valerii, Lucie Vysloužilová, Andrea Klápšťová, Emerson Coy, Mariusz Jancelewicz, and Igor Iatsunskyi. "Formation and Photoluminescence Properties of ZnO Nanoparticles on Electrospun Nanofibers Produced by Atomic Layer Deposition." Coatings 10, no. 12 (December 9, 2020): 1199. http://dx.doi.org/10.3390/coatings10121199.

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The unique combination of optical, chemical, and structural properties of one-dimensional zinc oxide (1D ZnO) makes it one of the most attractive materials in a wide range of research and applications. In the present study, 1D ZnO nanomaterials were fabricated using a combination of two independent methods: electrospinning and atomic layer deposition (ALD). The electrospinning technique was used to produce 1D electrospun fibers consisting of four types of polymers: polylactic acid (PLLA), polyvinylidene fluoride (PVDF), polyvinyl alcohol (PVA), and polyamide 6 (PA6). The ALD technology, in turn, was selected as an excellent candidate for the synthesis of a ZnO thin layer over polymer fibers for the production of 1D ZnO/polymer nanofiber composites (PLLA/ZnO, PVDF/ZnO, PVA/ZnO, PA6/ZnO). Structural and optical properties of the produced nanofibers were studied by means of scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), diffuse reflectance, and photoluminescence (PL) spectroscopy. It was found that only PVDF/ZnO nanofibers exhibit stable room temperature PL that may be the result of a higher ZnO content in the sample. In addition, PL measurements were conducted as a function of excitation power and temperature in order to establish the main PL mechanisms and parameters for the PVDF/ZnO sample, as a most promising candidate for the biophotonic application.

19

Andersson-Engels, Stefan, and Peter E. Andersen. "Special Section Guest Editorial:Selected Topics in Biophotonics: Photoacoustic Tomography and Fiber-Based Lasers and Supercontinuum Sources." Journal of Biomedical Optics 21, no. 6 (June 29, 2016): 061001. http://dx.doi.org/10.1117/1.jbo.21.6.061001.

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20

Zainuddin, Nurul H., Hui Y. Chee, Muhammad Z. Ahmad, Mohd A. Mahdi, Muhammad H. Abu Bakar, and Mohd H. Yaacob. "Inside Back Cover: Sensitive Leptospira DNA detection using tapered optical fiber sensor (J. Biophotonics 8/2018)." Journal of Biophotonics 11, no. 8 (August 2018): e201870153. http://dx.doi.org/10.1002/jbio.201870153.

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21

Kolle, Mathias, Alfred Lethbridge, Moritz Kreysing, Jeremy J. Baumberg, Joanna Aizenberg, and Peter Vukusic. "Biophotonics: Bio-Inspired Band-Gap Tunable Elastic Optical Multilayer Fibers (Adv. Mater. 15/2013)." Advanced Materials 25, no. 15 (April 12, 2013): 2248. http://dx.doi.org/10.1002/adma.201370095.

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22

Gil, José J., Ignacio San José, Mónica Canabal-Carbia, Irene Estévez, Emilio González-Arnay, Jordi Luque, Teresa Garnatje, Juan Campos, and Angel Lizana. "Polarimetric Images of Biological Tissues Based on the Arrow Decomposition of Mueller Matrices." Photonics 10, no. 6 (June 8, 2023): 669. http://dx.doi.org/10.3390/photonics10060669.

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Polarimetric techniques are widely used in a vast number of applications such as remote sensing, material characterization, astronomy and biological tissue inspection. In this last scenario, different polarimetric observables have proved their potential for enhancing imaging visualization. In this work we use a set of polarimetric observables derived from the arrow decomposition of the Mueller matrix for the first time: enpolarizing, retarding and depolarizing descriptors. In particular, the mean intensity coefficient and the three indices of polarimetric purity, the absolute values and Poincaré orientations of diattenuation, polarizance, entrance retardance and exit retardance vectors are considered. Results show images with enhanced visualization or even revealing invisible structures when compared to standard intensity images. In particular, thanks to these metrics, we improve the visualization of the necrotic areas of a Vitis rupestris leaf. In the case of animal samples, boundaries between different fascicles inside a tendon of an ex vivo chicken sample are revealed, as is the directionality of fiber tracts of the subcortical white matter in an ex vivo cow brain. The experimental results show the potential for biophotonics imaging and how polarimetric techniques could be useful for biomedical and botanical applications.

23

Alfonso-Garcia, Alba, Jeny Shklover, Benjamin E. Sherlock, Alyssa Panitch, Leigh G. Griffiths, and Laura Marcu. "Inside Cover: Fiber-based fluorescence lifetime imaging of recellularization processes on vascular tissue constructs (J. Biophotonics 9/2018)." Journal of Biophotonics 11, no. 9 (September 2018): e201870158. http://dx.doi.org/10.1002/jbio.201870158.

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24

Čižmár, Tomáš, and Kishan Dholakia. "Shaping the light transmission through a multimode optical fibre: complex transformation analysis and applications in biophotonics." Optics Express 19, no. 20 (September 14, 2011): 18871. http://dx.doi.org/10.1364/oe.19.018871.

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25

Kasianenko E. M., Omelchenko A. I., and Baum O. I. "Deformation response of biological phantoms and cartilaginous tissue at laser exposure." Optics and Spectroscopy 130, no. 6 (2022): 668. http://dx.doi.org/10.21883/eos.2022.06.54702.22-22.

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Regeneration of cartilaginous tissue and its shape change at laser exposure can be used as a basis for prospective medical operations, improving patient's quality of life. The most important criterion of such operations success is a cell survival after laser exposure, therefore reduction of exposure duration and power is an important task at such methods development. Nanoparticles are actively used in medicine, and one of their intended usages is photothermal effect enhancement at laser exposure to biological tissue. However, articular tissue is quite resistant to foreign agents penetration, therefore the study of nanoparticles penetration capability and their impregnation effect is the priority task for achieving the desired medical effect. Optical coherence tomography (OCT) of gel phantoms and cartilaginous tissue of a joint, impregnated with nanoparticles, at laser exposure with erbium fiber laser with length wave of 1.56 μm is performed in this study. Articular cartilaginous tissue sections of three types (intact, with laser damage and after low laser exposure) were impregnated with nanoparticles of Fe3O4 for further study using OCT elastography. Increase of deformations, caused by heating of phantoms and tissue, impregnated with nanoparticles, is observed. OCT elastography data indicate the dependence of tissue deformation on previous tissue exposure history. The work substantiates increase of photothermal impact of laser exposure to tissue deformation at various nanoparticles introduction. Keywords: nanoparticles, OCT elastography, biological tissue laser modification, biophotonics.

26

Zhang, Heng, Zhenyi Chen, Jiping Wu, Na Chen, Wenjie Xu, Taihao Li, and Shupeng Liu. "Back Cover: Laser stimulating ST36 with optical fiber induce blood component changes in mice: a Raman spectroscopy study (J. Biophotonics 6/2018)." Journal of Biophotonics 11, no. 6 (June 2018): e201870146. http://dx.doi.org/10.1002/jbio.201870146.

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27

Lemiere, A., A. Szczodra, S. Vuori, B. Bondzior, T. W. Hawkins, J. Ballato, M. Lastusaari, J. Massera, and Laeticia Petit. "Biophotonic Composite Fiber with Green Persistent Luminescence." SSRN Electronic Journal, 2021. http://dx.doi.org/10.2139/ssrn.3971629.

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28

Lemiere, A., A. Szczodra, S. Vuori, B. Bondzior, T. W. Hawkins, J. Ballato, M. Lastusaari, and Laeticia Petit. "Biophotonic Composite Fiber with Green Persistent Luminescence." SSRN Electronic Journal, 2021. http://dx.doi.org/10.2139/ssrn.3990810.

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Li, Xiangshan, Ragini Singh, Bingyuan Zhang, Santosh Kumar, and Guoru Li. "Development of a Biophotonic Fiber Sensor Using Direct-Taper and Anti-Taper Techniques with Seven-Core and Four-Core Fiber for the Detection of Doxorubicin in Cancer Treatment." Optics Express, April 12, 2024. http://dx.doi.org/10.1364/oe.525125.

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Scheibinger, Ramona, Niklas M. Lüpken, Mario Chemnitz, Kay Schaarschmidt, Jens Kobelke, Carsten Fallnich, and Markus A. Schmidt. "Higher-order mode supercontinuum generation in dispersion-engineered liquid-core fibers." Scientific Reports 11, no. 1 (March 5, 2021). http://dx.doi.org/10.1038/s41598-021-84397-1.

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AbstractSupercontinuum generation enabled a series of key technologies such as frequency comb sources, ultrashort pulse sources in the ultraviolet or the mid-infrared, as well as broadband light sources for spectroscopic methods in biophotonics. Recent advances utilizing higher-order modes have shown the potential to boost both bandwidth and modal output distribution of supercontinuum sources. However, the strive towards a breakthrough technology is hampered by the limited control over the intra- and intermodal nonlinear processes in the highly multi-modal silica fibers commonly used. Here, we investigate the ultrafast nonlinear dynamics of soliton-based supercontinuum generation and the associated mode coupling within the first three lowest-order modes of accurately dispersion-engineered liquid-core fibers. By measuring the energy-spectral evolutions and the spatial distributions of the various generated spectral features polarization-resolved, soliton fission and dispersive wave formation are identified as the origins of the nonlinear broadening. Measured results are confirmed by nonlinear simulations taking advantage of the accurate modeling capabilities of the ideal step-index geometry of our liquid-core platform. While operating in the telecommunications domain, our study allows further advances in nonlinear switching in emerging higher-order mode fiber networks as well as novel insights into the sophisticated nonlinear dynamics and broadband light generation in pre-selected polarization states.

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Turtaev, Sergey, Ivo T. Leite, and Tomáš Čižmár. "Multimode fibres for micro-endoscopy." Optofluidics, Microfluidics and Nanofluidics 2, no. 1 (January 31, 2015). http://dx.doi.org/10.1515/optof-2015-0004.

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AbstractThere has been a tremendous effort in modern microscopy towards miniaturisation and fibre-based technology, driven by the need to access hostile or difficult environments in situ and in vivo. Most of these rely on reducing the size of endoscopes based on fibre-optic bundles, and systems incorporating microfabricated lenses. Recently, the use of standard multimode optical fibres for lensless microscopy has become possible mainly due to advances in holographic beam shaping. This article reviews the methods and techniques behind this progress paving theway towards minimally invasive in vivo imaging as well as other applications of multimode waveguides including on-chip integration of optical micro-manipulation and numerous other biophotonics techniques.

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"Inside Cover: Raman ChemLighter: Fiber optic Raman probe imaging in combination with augmented chemical reality (J. Biophotonics 7/2019)." Journal of Biophotonics 12, no. 7 (July 2019). http://dx.doi.org/10.1002/jbio.201970023.

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"Back Cover: Diaphragm‐based optical fiber sensor for pulse wave monitoring and cardiovascular diseases diagnosis (J. Biophotonics 10/2019)." Journal of Biophotonics 12, no. 10 (October 2019). http://dx.doi.org/10.1002/jbio.201970037.

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Hou Chen-Yang, Meng Fan-Chao, Zho Yi-Ming, Ding Jin-Min, Zhao Xiao-Ting, Hong-wei Liu, Wang Xin, Lou Shu-Qin, Sheng Xin-Zhi, and Liang Sheng. "“Machine Scientist of Micro/Nano Optics”: application and development of artificial intelligence in micro/nano optical design." Acta Physica Sinica, 2023, 0. http://dx.doi.org/10.7498/aps.72.20230208.

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Micro/nano optical materials and devices are the key to many optical fields such as optical communication, optical sensing, biophotonics, laser, quantum optics, etc. At present, the design of micro/nano optics mainly relies on the simulation of numerical methods such as Finite-difference time-domain (FDTD), Finite element method (FEM) and Finite difference method (FDM), which These methods are bottlenecks in current micro/nano optical design because of their dependence on computational resources, low innovation efficiency, and difficulties in obtaining global optimal design. Artificial intelligence (AI) has brought a new paradigm of scientific research: AI for Science, which has been successfully applied to chemistry, materials science, quantum mechanics, and particle physics. In the area of micro/nano design AI has been applied to the design research of chiral materials, power dividers, microstructured optical fibers, photonic crystal fibers, chalcogenide solar cells, plasma waveguides and so on. According to the characteristics of the micro/nano optical design objects, the data sets can be constructed in the form of parameter vectors for complex micro/nano optical designs such as hollow core anti-resonant fibers with multi-layer nested tubes, and in the form of images for simple micro/nano optical designs such as 3dB couplers. The constructed datasets are trained with artificial neural network, deep neural network and convolutional neural net algorithms to build regression or classification tasks for performance prediction or inverse design of micro/nano optics. The constructed AI models are optimized by adjusting performance evaluation metrics such as mean square error, mean absolute error, and binary cross entropy. In this paper, the application of AI in micro/nano optics design is reviewed, the application methods of AI in micro/nano optics are summarized, and the difficulties and future development trends of AI in micro/nano optics research are analyzed and prospected.

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Toh, Darel Wee Kiat, Wen Wei Loh, Clarinda Nataria Sutanto, Yuanhang Yao, and Jung Eun Kim. "Skin carotenoid status and plasma carotenoids: biomarkers of dietary carotenoids, fruits and vegetables for middle-aged and older Singaporean adults." British Journal of Nutrition, January 14, 2021, 1–10. http://dx.doi.org/10.1017/s0007114521000143.

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Abstract Skin carotenoid status (SCS) measured by resonance Raman spectroscopy (RRS) may serve as an emerging alternative measurement for dietary carotenoid, fruit and vegetable (FV) intake although its application had not been assessed in a middle-aged and older population in Asia. This cross-sectional study aims to concurrently examine the use of SCS and plasma carotenoids to measure FV and carotenoid intake in a middle-aged and older population, taking into consideration potential socio-demographic and nutritional confounders. The study recruited 103 middle-aged and older adults (mean age: 58 years) in Singapore. Dietary carotenoids and FV, plasma carotenoid concentration and SCS were measured using 3-d food records, HPLC and a biophotonic scanner which utilised RRS, respectively. Adjusted for statistically defined socio-demographic covariates sex, age, BMI, prescription medication and cigarette smoking, plasma carotenoids and SCS showed positive associations with dietary total carotenoids (βplasma: 0·020 (95 % CI 0·000, 0·040) µmol/l/mg, P = 0·05; βskin: 265 (95 % CI 23, 506) arbitrary units/mg, P = 0·03) and FV (βplasma: 0·076 (95 % CI 0·021, 0·132) µmol/l per FV serving, P = 0·008; βskin: 1036 (95 % CI 363, 1708) arbitrary units/FV serving, P = 0·003). The associations of SCS with dietary carotenoid and FV intake were null with the inclusion of dietary PUFA, fibre and vitamin C as nutritional covariates (P > 0·05). This suggests a potential influence of these nutritional factors on carotenoid circulation and deposition in the skin. In conclusion, SCS, similar to plasma carotenoids, may serve as a biomarker for both dietary carotenoid and FV intake in a middle-aged and older Singaporean population.

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"Front Cover: Surface‐enhanced Raman scattering‐active photonic crystal fiber probe: Towards next generation liquid biopsy sensor with ultra high sensitivity (J. Biophotonics 11/2019)." Journal of Biophotonics 12, no. 11 (November 2019). http://dx.doi.org/10.1002/jbio.201970038.

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