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Статті в журналах з теми "Biomolecular Devices"

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Dey, D., and T. Goswami. "Optical Biosensors: A Revolution Towards Quantum Nanoscale Electronics Device Fabrication." Journal of Biomedicine and Biotechnology 2011 (2011): 1–7. http://dx.doi.org/10.1155/2011/348218.

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The dimension of biomolecules is of few nanometers, so the biomolecular devices ought to be of that range so a better understanding about the performance of the electronic biomolecular devices can be obtained at nanoscale. Development of optical biomolecular device is a new move towards revolution of nano-bioelectronics. Optical biosensor is one of such nano-biomolecular devices that has a potential to pave a new dimension of research and device fabrication in the field of optical and biomedical fields. This paper is a very small report about optical biosensor and its development and importance in various fields.
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Miró, Jesús M., and Alfonso Rodríguez-Patón. "Biomolecular Computing Devices in Synthetic Biology." International Journal of Nanotechnology and Molecular Computation 2, no. 2 (April 2010): 47–64. http://dx.doi.org/10.4018/978-1-59904-996-0.ch014.

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Synthetic biology and biomolecular computation are disciplines that fuse when it comes to designing and building information processing devices. In this chapter, we study several devices that are representative of this fusion. These are three gene circuits implementing logic gates, a DNA nanodevice and a biomolecular automaton. The operation of these devices is based on gene expression regulation, the so-called competitive hybridization and the workings of certain biomolecules like restriction enzymes or regulatory proteins. Synthetic biology, biomolecular computation, systems biology and standard molecular biology concepts are also defined to give a better understanding of the chapter. The aim is to acquaint readers with these biomolecular devices born of the marriage between synthetic biology and biomolecular computation.
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Yoshimine, Hiroshi, Kai Sasaki, and Hiroyuki Furusawa. "Pocketable Biosensor Based on Quartz-Crystal Microbalance and Its Application to DNA Detection." Sensors 23, no. 1 (December 27, 2022): 281. http://dx.doi.org/10.3390/s23010281.

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Quartz-crystal microbalance (QCM) is a technique that can measure nanogram-order masses. When a receptor is immobilized on the sensor surface of a QCM device, the device can detect chemical molecules captured by the mass change. Although QCM devices have been applied to biosensors that detect biomolecules without labels for biomolecular interaction analysis, most highly sensitive QCM devices are benchtop devices. We considered the fabrication of an IC card-sized QCM device that is both portable and battery-powered. Its miniaturization was achieved by repurposing electronic components and film batteries from smartphones and wearable devices. To demonstrate the applicability of the card-sized QCM device as a biosensor, DNA-detection experiments were performed. The card-sized QCM device could detect specific 10-mer DNA chains while discerning single-base differences with a sensitivity similar to that of a conventional benchtop device. The card-sized QCM device can be used in laboratories and in various other fields as a mass sensor.
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Malhotra, B. D., and Rahul Singhal. "Conducting polymer based biomolecular electronic devices." Pramana 61, no. 2 (August 2003): 331–43. http://dx.doi.org/10.1007/bf02708313.

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Montemagno, Carlo, and George Bachand. "Constructing nanomechanical devices powered by biomolecular motors." Nanotechnology 10, no. 3 (August 12, 1999): 225–31. http://dx.doi.org/10.1088/0957-4484/10/3/301.

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Alam, Sadaf R., Pratul K. Agarwal, Melissa C. Smith, Jeffrey S. Vetter, and David Caliga. "Using FPGA Devices to Accelerate Biomolecular Simulations." Computer 40, no. 3 (March 2007): 66–73. http://dx.doi.org/10.1109/mc.2007.108.

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Espinosa, Francisco, Manuel Uhlig, and Ricardo Garcia. "Molecular Recognition by Silicon Nanowire Field-Effect Transistor and Single-Molecule Force Spectroscopy." Micromachines 13, no. 1 (January 8, 2022): 97. http://dx.doi.org/10.3390/mi13010097.

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Silicon nanowire (SiNW) field-effect transistors (FETs) have been developed as very sensitive and label-free biomolecular sensors. The detection principle operating in a SiNW biosensor is indirect. The biomolecules are detected by measuring the changes in the current through the transistor. Those changes are produced by the electrical field created by the biomolecule. Here, we have combined nanolithography, chemical functionalization, electrical measurements and molecular recognition methods to correlate the current measured by the SiNW transistor with the presence of specific molecular recognition events on the surface of the SiNW. Oxidation scanning probe lithography (o-SPL) was applied to fabricate sub-12 nm SiNW field-effect transistors. The devices were applied to detect very small concentrations of proteins (500 pM). Atomic force microscopy (AFM) single-molecule force spectroscopy (SMFS) experiments allowed the identification of the protein adsorption sites on the surface of the nanowire. We detected specific interactions between the biotin-functionalized AFM tip and individual avidin molecules adsorbed to the SiNW. The measurements confirmed that electrical current changes measured by the device were associated with the deposition of avidin molecules.
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Fujimoto, Keiji. "Design and Synthesis of Biomolecular Devices Using Liposomes." MEMBRANE 30, no. 6 (2005): 293–97. http://dx.doi.org/10.5360/membrane.30.293.

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Bachand, George D., Nathan F. Bouxsein, Virginia VanDelinder, and Marlene Bachand. "Biomolecular motors in nanoscale materials, devices, and systems." Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 6, no. 2 (December 11, 2013): 163–77. http://dx.doi.org/10.1002/wnan.1252.

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Lara, Sandra, and André Perez-Potti. "Applications of Nanomaterials for Immunosensing." Biosensors 8, no. 4 (November 1, 2018): 104. http://dx.doi.org/10.3390/bios8040104.

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In biomedical science among several other growing fields, the detection of specific biological agents or biomolecular markers, from biological samples is crucial for early diagnosis and decision-making in terms of appropriate treatment, influencing survival rates. In this regard, immunosensors are based on specific antibody-antigen interactions, forming a stable immune complex. The antigen-specific detection antibodies (i.e., biomolecular recognition element) are generally immobilized on the nanomaterial surfaces and their interaction with the biomolecular markers or antigens produces a physico-chemical response that modulates the signal readout. Lowering the detection limits for particular biomolecules is one of the key parameters when designing immunosensors. Thus, their design by combining the specificity and versatility of antibodies with the intrinsic properties of nanomaterials offers a plethora of opportunities for clinical diagnosis. In this review, we show a comprehensive set of recent developments in the field of nanoimmunosensors and how they are progressing the detection and validation for a wide range of different biomarkers in multiple diseases and what are some drawbacks and considerations of the uses of such devices and their expansion.
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Дисертації з теми "Biomolecular Devices"

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Heucke, Stephan F. "Advancing nanophotonic devices for biomolecular analysis." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-165294.

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Melli, Mauro. "Mechanical resonating devices and their applications in biomolecular studies." Doctoral thesis, SISSA, 2010. http://hdl.handle.net/20.500.11767/4646.

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To introduce the reader in the subjects of the thesis, Chapter 1 provides an overview on the different aspects of the mechanical sensors. After a brief introduction to NEMS/MEMS, the different approaches of mechanical sensing are provided and the main actuation and detection schemes are described. The chapter ends with an introduction to microfabrication. Chapter 2 deals with experimental details. In first paragraph the advantages of using a pillar instead of common horizontal cantilever are illustrated. Then, the fabrication procedures and the experimental setup for resonance frequencies measurement are described. The concluding paragraph illustrates the technique, known as dip and dry, I used for coupling mechanical detection with biological problems. In Chapter 3, DNA kinetics of adsorption and hybridization efficiency, measured by means of pillar approach, are reported. Chapter 4 gives an overview of the preliminary results of two novel applications of pillar approach. They are the development of a protein chip technology based on pillars and the second is the combination of pillars and nanografting, an AFM based nanolithography. Chapter 5 starts with an introduction about the twin cantilever approach and of the mechanically induced functionalization. Fabrication procedure is described in the second paragraph. Then the chemical functionalizations are described and proved. Cleaved surface analyses and the spectroscopic studies of the mechanically induced functionalization are reported. In Appendix A there is an overview of the physical models that are used in this thesis.
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Sawlekar, Rucha. "Programming dynamic nonlinear biomolecular devices using DNA strand displacement reactions." Thesis, University of Warwick, 2016. http://wrap.warwick.ac.uk/91757/.

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Recent advances in DNA computing have greatly facilitated the design of biomolecular circuitry based on toehold-mediated DNA strand displacement (DSD) reactions. The synthesis of biomolecular circuits for controlling molecular-scale processes is an important goal of synthetic biology with a wide range of in vitro and in vivo applications. In this thesis, new results are presented on how chemical reaction networks (CRNs) can be used as a programming language to implement commonly used linear and nonlinear system theoretic operators that can be further utilised in combination to form complex biomolecular circuits. Within the same framework, the design of an important class of nonlinear feedback controller, i.e. a quasi sliding mode (QSM) feedback controller, is proposed. The closed loop response of the nonlinear QSM controller is shown to outperform a traditional linear proportional+integrator (PI) controller by facilitating much faster tracking response dynamics without introducing overshoots in the transient response. The resulting controller is highly modular and is less affected by retroactivity effects than standard linear designs. An important issue to consider in this design process for synthetic circuits is the effect of biological and experimental uncertainties on the functionality and reliability of the overall circuit. In the case of biomolecular feedback control circuits, such uncertainties could lead to a range of adverse effects, including achieving wrong concentration levels, sluggish performance and even instability. In this thesis, the robustness properties of two biomolecular feedback controllers; PI and QSM, subject to uncertainties in the experimentally implemented rates of their underlying chemical reactions, and to variations in accumulative time delays in the process to be controlled, are analysed. The simulation results show that the proposed QSM controller is significantly more robust against investigated uncertainties, highlighting its potential as a practically implementable biomolecular feedback controller for future synthetic biology applications. Finally, the thesis presents new results on the design of biomolecular feedback controllers using the set of chemical reactions underlying covalent modification cycles.
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Kearns, Gregory Justin. "Engineering interfaces at the micro- and nanoscale for biomolecular and nanoparticle self-assembled devices /." view abstract or download file of text, 2007. http://proquest.umi.com/pqdweb?did=1417810561&sid=2&Fmt=2&clientId=11238&RQT=309&VName=PQD.

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Thesis (Ph. D.)--University of Oregon, 2007.
Typescript. Includes vita and abstract. Includes bibliographical references (leaves 158-174). Also available for download via the World Wide Web; free to University of Oregon users.
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Malmstadt, Noah. "Temperature-dependant [sic] smart bead adhesion : a versatile platform for biomolecular immobilization in microfluidic devices /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/8019.

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Tiwari, Purushottam Babu. "Multimode Analysis of Nanoscale Biomolecular Interactions." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/1923.

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Biomolecular interactions, including protein-protein, protein-DNA, and protein-ligand interactions, are of special importance in all biological systems. These interactions may occer during the loading of biomolecules to interfaces, the translocation of biomolecules through transmembrane protein pores, and the movement of biomolecules in a crowded intracellular environment. The molecular interaction of a protein with its binding partners is crucial in fundamental biological processes such as electron transfer, intracellular signal transmission and regulation, neuroprotective mechanisms, and regulation of DNA topology. In this dissertation, a customized surface plasmon resonance (SPR) has been optimized and new theoretical and label free experimental methods with related analytical calculations have been developed for the analysis of biomolecular interactions. Human neuroglobin (hNgb) and cytochrome c from equine heart (Cyt c) proteins have been used to optimize the customized SPR instrument. The obtained Kd value (~13 µM), from SPR results, for Cyt c-hNgb molecular interactions is in general agreement with a previously published result. The SPR results also confirmed no significant impact of the internal disulfide bridge between Cys 46 and Cys 55 on hNgb binding to Cyt c. Using SPR, E. coli topoisomerase I enzyme turnover during plasmid DNA relaxation was found to be enhanced in the presence of Mg2+. In addition, a new theoretical approach of analyzing biphasic SPR data has been introduced based on analytical solutions of the biphasic rate equations. In order to develop a new label free method to quantitatively study protein-protein interactions, quartz nanopipettes were chemically modified. The derived Kd (~20 µM) value for the Cyt c-hNgb complex formations matched very well with SPR measurements (Kd ~16 µM). The finite element numerical simulation results were similar to the nanopipette experimental results. These results demonstrate that nanopipettes can potentially be used as a new class of a label-free analytical method to quantitatively characterize protein-protein interactions in attoliter sensing volumes, based on a charge sensing mechanism. Moreover, the molecule-based selective nature of hydrophobic and nanometer sized carbon nanotube (CNT) pores was observed. This result might be helpful to understand the selective nature of cellular transport through transmembrane protein pores.
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Hahn, Jaeseung. "Programmable biomolecular integration and dynamic behavior of DNA-based systems for development of biomedical nano-devices." Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/122213.

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Thesis: Ph. D. in Medical Engineering and Medical Physics, Harvard-MIT Program in Health Sciences and Technology, 2019
Cataloged from PDF version of thesis.
Includes bibliographical references.
Departing from the traditional role as a carrier of genetic information, DNA has emerged as an engineering material for construction of nano-devices. The advances in the field of DNA nanotechnology have enabled design and synthesis of DNA nanostructures of arbitrary shapes and manipulation of the nanostructures' conformations in a programmable way. DNA-based systems offer potential applications in medicine by manipulating the biological components and processes that occur at the nanometer scale. To accelerate the translation of DNA-based systems for medical applications, we identified some of the challenges that are hindering our ability to construct biomedical nano-devices and addressed these challenges through advances in both structural and dynamic DNA nanotechnology. First, we tested the stability of DNA nanostructures in biological environments to highlight the necessity of and path towards protection strategies for prolonged integrity of biomedical nano-devices. Then, we constructed a platform for robust 3D molecular integration using DNA origami technique and implemented the platform for a nanofactory capable of production of therapeutic RNA to overcome the challenges in RNA delivery. Moreover, we established a mechanism to drive DNA devices by changing temperature with prolonged dynamic behavior that was previously challenging to accomplish without special modification of DNA and/or equipment not readily available in a typical lab setting. Together, the progress made in this thesis bring us another step closer to realization of medical applications of DNA nanotechnology by focusing on the challenges in both structural and dynamic aspects of the technology.
by Jaeseung Hahn.
Ph. D. in Medical Engineering and Medical Physics
Ph.D.inMedicalEngineeringandMedicalPhysics Harvard-MIT Program in Health Sciences and Technology
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Razaq, Aamir. "Development of Cellulose-Based, Nanostructured, Conductive Paper for Biomolecular Extraction and Energy Storage Applications." Doctoral thesis, Uppsala universitet, Nanoteknologi och funktionella material, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-158444.

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Conductive paper materials consisting of conductive polymers and cellulose are promising for high-tech applications (energy storage and biosciences) due to outstanding aspects of environmental friendliness, mechanical flexibility, electrical conductivity and efficient electroactive behavior. Recently, a conductive composite paper material was developed by covering the individual nanofibers of cellulose from the green algae Cladophora with a polypyrrole (PPy) layer. The PPy-Cladophora cellulose composite paper is featured with high surface area (80 m2 g-1), electronic conductivity (~2 S cm-1), thin conductive layer (~50 nm) and easily up-scalable manufacturing process. This doctoral thesis reports the development of the PPy-Cladophora composite as an electrode material in electrochemically controlled solid phase ion-exchange of biomolecules and all-polymer based energy storage devices. First, electrochemical ion-exchange properties of the PPy-Cladophora cellulose composite were investigated in electrolytes containing three different types of anions, and it was found that smaller anions (nitrate and chloride) are more readily extracted by the composite than lager anions (p-toluene sulfonate). The influence of differently sized oxidants used during polymerization on the anion extraction capacity of the composite was also studied. The composites synthesized with two different oxidizing agents, i.e. iron (III) chloride and phosphomolybdic acid (PMo), were investigated for their ability to extract anions of different sizes. It was established that the number of absorbed ions was larger for the iron (III) chloride-synthesized sample than for the PMo-synthesized sample for all four electrolytes studied. Further, PPy-Cladophora cellulose composites have shown remarkable electrochemically controlled ion extraction capacities when investigated as a solid phase extraction material for batch-wise extraction and release of DNA oligomers. In addition, composite paper was also investigated as an electrode material in the symmetric non-metal based energy storage devices. The salt and paper based energy storage devices exhibited charge capacities (38−50 mAh g−1) with reasonable cycling stability, thereby opening new possibilities for the production of environmentally friendly, cost efficient, up-scalable and lightweight energy storage systems. Finally, micron-sized chopped carbon fibers (CCFs) were incorporated as additives to improve the charge-discharge rates of paper-based energy storage devices and to enhance the DNA release efficiency. The results showed the independent cell capacitances of ~60-70 F g-1 (upto current densities of 99 mA cm2) and also improved the efficiency of DNA release from 25 to 45%.
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Heucke, Stephan F. Verfasser], and Hermann E. [Akademischer Betreuer] [Gaub. "Advancing nanophotonic devices for biomolecular analysis : force spectroscopy and nanopositioning of single molecules in zero-mode waveguides / Stephan F. Heucke. Betreuer: Hermann Gaub." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2013. http://d-nb.info/1046785311/34.

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Absher, Jason Matthew. "THE DEVELOPMENT OF MICROFLUIDIC DEVICES FOR THE PRODUCTION OF SAFE AND EFFECTIVE NON-VIRAL GENE DELIVERY VECTORS." UKnowledge, 2018. https://uknowledge.uky.edu/cme_etds/85.

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Including inherited genetic diseases, like lipoprotein lipase deficiency, and acquired diseases, such as cancer and HIV, gene therapy has the potential to treat or cure afflicted people by driving an affected cell to produce a therapeutic protein. Using primarily viral vectors, gene therapies are involved in a number of ongoing clinical trials and have already been approved by multiple international regulatory drug administrations for several diseases. However, viral vectors suffer from serious disadvantages including poor transduction of many cell types, immunogenicity, direct tissue toxicity and lack of targetability. Non-viral polymeric gene delivery vectors (polyplexes) provide an alternative solution but are limited by poor transfection efficiency and cytotoxicity. Microfluidic (MF) nano-precipitation is an emerging field in which researchers seek to tune the physicochemical properties of nanoparticles by controlling the flow regime during synthesis. Using this approach, several groups have demonstrated the successful production of enhanced polymeric gene delivery vectors. It has been shown that polyplexes created in the diffusive flow environment have a higher transfection efficiency and lower cytotoxicity. Other groups have demonstrated that charge-stabilizing polyplexes by sequentially adding polymers of alternating charges improves transfection efficiency and serum stability, also addressing major challenges to the clinical implementation of non-viral gene delivery vectors. To advance non-viral gene delivery towards clinical relevance, we have developed a microfluidic platform (MS) that produces conventional polyplexes with increased transfection efficiency and decreased toxicity and then extended this platform for the production of ternary polyplexes. This work involves first designing microfluidic devices using computational fluid dynamics (CFD), fabricating the devices, and validating the devices using fluorescence flow characterization and absorbance measurements of the resulting products. With an integrated separation mechanism, excess polyethylenimine (PEI) is removed from the outer regions of the stream leaving purified polyplexes that can go on to be used directly in transfections or be charge stabilized by addition of polyanions such as polyglutamic acid (PGA) for the creation of ternary polyplexes. Following the design portion of the research, the device was used to produce binary particle characterization was carried out and particle sizes, polydispersity and zeta potential of both conventional and MS polyplexes was compared. MS-produced polyplexes exhibited up to a 75% reduction in particle size compared to BM-produced polyplexes, while exhibiting little difference in zeta potential and polydispersity. A variety of standard biological assays were carried out to test the effects of the vectors on a variety of cell lines – and in this case the MS polyplexes proved to be both less toxic and have higher transfection efficiency in most cell lines. HeLa cells demonstrated the highest increase in transgene expression with a 150-fold increase when comparing to conventional bulk mixed polyplexes at the optimum formulation. A similar set of experiments were carried out with ternary polyplexes produced by the separation device. In this case it was shown that there were statistically significant increases in transfection efficiency for the MS-produced ternary polyplexes compared to BM-produced poyplexes, with a 23-fold increase in transfection activity at the optimum PEI/DNA ratio in MDAMB-231 cells. These MS-produced ternary polyplexes exhibited higher cell viability in many instances, a result that may be explained but the reduction in both free polymer and ghost particles.
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Книги з теми "Biomolecular Devices"

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Jia, Yuan. Polymer-Based MEMS Calorimetric Devices for Characterization of Biomolecular Interactions. [New York, N.Y.?]: [publisher not identified], 2017.

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1956-, Köhler J. M., Mejevaia T, and Saluz H. P. 1952-, eds. Microsystem technology: A powerful tool for biomolecular studies. Basel, Switzerland: Birkhäuser Verlag, 1999.

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Bryant, Richard. Optically active polymers, organometallics, and biomolecular materials/devices: A technical/economic analysis. Norwalk, CT: Business Communications Co., 1991.

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Sharda, D. S., and Bansi D. Malhotra. Graphene Based Biomolecular Electronic Devices. Elsevier, 2022.

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Sharda, D. S., and Bansi D. Malhotra. Graphene Based Biomolecular Electronic Devices. Elsevier, 2022.

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Ibrahim, Mohamed, and Krishnendu Chakrabarty. Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms. Taylor & Francis Group, 2020.

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Ibrahim, Mohamed, and Krishnendu Chakrabarty. Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms. Taylor & Francis Group, 2020.

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Ibrahim, Mohamed, and Krishnendu Chakrabarty. Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms. Taylor & Francis Group, 2020.

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Narlikar, A. V., and Y. Y. Fu, eds. Oxford Handbook of Nanoscience and Technology. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199533060.001.0001.

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This volume highlights engineering and related developments in the field of nanoscience and technology, with a focus on frontal application areas like silicon nanotechnologies, spintronics, quantum dots, carbon nanotubes, and protein-based devices as well as various biomolecular, clinical and medical applications. Topics include: the role of computational sciences in Si nanotechnologies and devices; few-electron quantum-dot spintronics; spintronics with metallic nanowires; Si/SiGe heterostructures in nanoelectronics; nanoionics and its device applications; and molecular electronics based on self-assembled monolayers. The volume also explores the self-assembly strategy of nanomanufacturing of hybrid devices; templated carbon nanotubes and the use of their cavities for nanomaterial synthesis; nanocatalysis; bifunctional nanomaterials for the imaging and treatment of cancer; protein-based nanodevices; bioconjugated quantum dots for tumor molecular imaging and profiling; modulation design of plasmonics for diagnostic and drug screening; theory of hydrogen storage in nanoscale materials; nanolithography using molecular films and processing; and laser applications in nanotechnology. The volume concludes with an analysis of the various risks that arise when using nanomaterials.
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Частини книг з теми "Biomolecular Devices"

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Reed, Mark A., and Alan C. Seabaugh. "Prospects for Semiconductor Quantum Devices." In Molecular and Biomolecular Electronics, 15–42. Washington, DC: American Chemical Society, 1994. http://dx.doi.org/10.1021/ba-1994-0240.ch002.

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Hong, Felix T. "Retinal Proteins in Photovoltaic Devices." In Molecular and Biomolecular Electronics, 527–59. Washington, DC: American Chemical Society, 1994. http://dx.doi.org/10.1021/ba-1994-0240.ch022.

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Albrecht, O., K. Sakai, K. Takimoto, H. Matsuda, K. Eguchi, and T. Nakagiri. "Molecular Devices Using Langmuir-Blodgett Films." In Molecular and Biomolecular Electronics, 341–71. Washington, DC: American Chemical Society, 1994. http://dx.doi.org/10.1021/ba-1994-0240.ch013.

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Katz, Evgeny. "Bioelectronic Devices Controlled by Enzyme-Based Information Processing Systems." In Biomolecular Information Processing, 61–80. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527645480.ch4.

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Lawrence, Albert F., and Robert R. Birge. "Fundamentals of Reliability Calculations for Molecular Devices and Photochromic Memories." In Molecular and Biomolecular Electronics, 131–60. Washington, DC: American Chemical Society, 1994. http://dx.doi.org/10.1021/ba-1994-0240.ch006.

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Fendler, Janos H. "Colloid Chemical Approach to Band-Gap Engineering and Quantum-Tailored Devices." In Molecular and Biomolecular Electronics, 413–38. Washington, DC: American Chemical Society, 1994. http://dx.doi.org/10.1021/ba-1994-0240.ch016.

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Moraes, Christopher, Yu Sun, and Craig A. Simmons. "Microfabricated Devices for Studying Cellular Biomechanics and Mechanobiology." In Cellular and Biomolecular Mechanics and Mechanobiology, 145–75. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/8415_2010_24.

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Cavaliere, Matteo, Nataša Jonoska, Sivan Yogev, Ron Piran, Ehud Keinan, and Nadrian C. Seeman. "Biomolecular Implementation of Computing Devices with Unbounded Memory." In DNA Computing, 35–49. Berlin, Heidelberg: Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/11493785_4.

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Reif, John H., and Thomas H. LaBean. "Engineering Natural Computation by Autonomous DNA-Based Biomolecular Devices." In Handbook of Natural Computing, 1319–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-92910-9_39.

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Reif, John H., and Thomas H. LaBean. "Autonomous Programmable Biomolecular Devices Using Self-assembled DNA Nanostructures." In Logic, Language, Information and Computation, 297–306. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-73445-1_21.

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Тези доповідей конференцій з теми "Biomolecular Devices"

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Villanueva, Guillermo, Gemma Rius, Josep Montserrat, Francesc Perez-Murano, and Joan Bausells. "Piezoresistive Microcantilevers for Biomolecular Force Detection." In 2007 Spanish Conference on Electron Devices. IEEE, 2007. http://dx.doi.org/10.1109/sced.2007.384029.

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Xiangrong Liu, Xiaoying shi, and Ying Ju. "A programmable biomolecular computing devices with RNAi." In 2010 IEEE Fifth International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA). IEEE, 2010. http://dx.doi.org/10.1109/bicta.2010.5645089.

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Bachand, George D., and Carlo D. Montemagno. "Constructing biomolecular motor-powered hybrid NEMS devices." In Asia Pacific Symposium on Microelectronics and MEMS, edited by Kevin H. Chau and Sima Dimitrijev. SPIE, 1999. http://dx.doi.org/10.1117/12.364481.

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Majumdar, Arun. "Integrated Nanofluidic Devices and Circuits." In ASME 4th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2006. http://dx.doi.org/10.1115/icnmm2006-96070.

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Анотація:
The fundamental length scales related to ions and molecules in liquids fall in the range of 1–100 nm. These involves the range of intermolecular forces due to steric interactions, electrostatic forces between charged species, and van der Waals interactions. This talk will focus on how confinement of aqueous solutions in the range of Debye screening length (1–50 nm) in nanochannels can lead to formation of unipolar ionic solutions. The ionic current in such nanochannels is found to several orders of magnitude higher than that predicted by macroscopic theories, and is extremely sensitive to surface charge, which can be used to study surface biomolecular reactions. Furthermore, this phenomenon can be exploited to develop nanofluidic transistors, diodes, and integrated circuits, which is now forming the basis for manipulating and analyzing complex mixtures of biomolecules in ultrasmall volumes.
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Densmore, Adam, Dan-Xia Xu, Philip Waldron, Siegfried Janz, Jean Lapointe, Trevor Mischki, Gregory Lopinski, André Delâge, and Pavel Cheben. "Spotter-compatible SOI waveguide devices for biomolecular sensing." In Integrated Optoelectronic Devices 2008, edited by Joel A. Kubby and Graham T. Reed. SPIE, 2008. http://dx.doi.org/10.1117/12.763699.

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Karnik, Rohit, Chuanhua Duan, Kenneth Castelino, Rong Fan, Peidong Yang, and Arun Majumdar. "Transport of Ions and Molecules in Nanofluidic Devices." In ASME 2008 6th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2008. http://dx.doi.org/10.1115/icnmm2008-62065.

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Анотація:
Interesting transport phenomena arise when fluids are confined to nanoscale dimensions in the range of 1–100 nm. We examine three distinct effects that influence ionic and molecular transport as the size of fluidic channels is decreased to the nanoscale. First, the length scale of electrostatic interactions in aqueous solutions becomes comparable to nanochannel size and the number of surface charges becomes comparable to the number of ions in the channel. Second, the size of the channel becomes comparable to the size of biomolecules such as proteins and DNA. Third, large surface area-to-volume ratios result in rapid rates of surface reactions and can dramatically affect transport of molecules through the channel. These phenomena enable us to control transport of ions and molecules in unique ways that are not possible in larger channels. Electrostatic interactions enable local control of ionic concentrations and transport inside nanochannels through field effect in a nanofluidic transistor, which is analogous to the metal-oxide-semiconductor field effect transistor. Furthermore, by controlling surface charge in nanochannels, it is possible to create a nanofluidic diode that rectifies ionic transport through the channel. Biological binding events result in partial blockage of the channel, and can thus be sensed by a decrease in nanochannel conductance. At low ionic concentrations, the effect of biomolecular charge is dominant and it can lead to an increase in conductance. Surface reactions can also be used to control transport of molecules though the channel due to the large surface area-to-volume ratios. Rapid surface reactions enable a new technique of diffusion-limited patterning (DLP), which is useful for patterning of biomolecules and surface charge in nanochannels. These examples illustrate how electrostatic interactions, biomolecular size, and surface reactions can be used for controlling ionic and molecular transport through nanochannels. These phenomena may be useful for operations such as analyte focusing, pH and ionic concentration control, and biosensing in micro- and nanofluidic devices.
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Miyahara, Y., C. Hamai-Kataoka, A. Matsumoto, T. Goda, and Y. Maeda. "Detection of biomolecular recognition using Bio-transistors." In 2010 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 2010. http://dx.doi.org/10.7567/ssdm.2010.l-1-1.

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Krasinski, Tadeusz, Sebastian Sakowski, and Tomasz Poplawski. "Towards an autonomous multistate biomolecular devices built on DNA." In 2014 Sixth World Congress on Nature and Biologically Inspired Computing (NaBIC). IEEE, 2014. http://dx.doi.org/10.1109/nabic.2014.6921899.

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Yao, Baoli, Dalun Xu, and Xun Hou. "Oriented bacteriorhodopsin film biomolecular devices and their photoelectric dynamics." In 22nd Int'l Congress on High-Speed Photography and Photonics, edited by Dennis L. Paisley and ALan M. Frank. SPIE, 1997. http://dx.doi.org/10.1117/12.273484.

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Tosolini, Giordano, Francesc Perez-Murano, Joan Bausells, and Luis Guillermo Villanueva. "Self sensing cantilevers for the measurement of (biomolecular) forces." In 2011 Spanish Conference on Electron Devices (CDE). IEEE, 2011. http://dx.doi.org/10.1109/sced.2011.5744171.

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Звіти організацій з теми "Biomolecular Devices"

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Lundgren, Cynthia A., David Baker, Barry Bruce, Maggie Hurley, Amy K. Manocchi, Scott Pendley, and James Sumner. Hydrogen Production from Water by Photosynthesis System I for Use as Fuel in Energy Conversion Devices (a.k.a. Understanding Photosystem I as a Biomolecular Reactor for Energy Conversion). Fort Belvoir, VA: Defense Technical Information Center, April 2014. http://dx.doi.org/10.21236/ada601589.

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Zhao, Yan. Mesoporous silica nanoparticles as smart and safe devices for regulating blood biomolecule levels. Office of Scientific and Technical Information (OSTI), January 2011. http://dx.doi.org/10.2172/1029552.

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