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Статті в журналах з теми "Binding component"

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Автор: Grafiati

Опубліковано: 30 травня 2022

Оновлено: 31 травня 2022

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1

de Frutos, Pablo García, Ylva Härdig, and Björn Dahlbäck. "Serum Amyloid P Component Binding to C4b-binding Protein." Journal of Biological Chemistry 270, no. 45 (November 10, 1995): 26950–55. http://dx.doi.org/10.1074/jbc.270.45.26950.

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2

Comis, Alfio, and Simon B. Easterbrook-Smith. "Binding of complement component C1q by spectrin." Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 870, no. 3 (April 1986): 426–31. http://dx.doi.org/10.1016/0167-4838(86)90250-5.

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3

SAKAMOTO, KAZUYUKI, H. M. ZHANG, and ROGER I. G. UHRBERG. "HIGH-RESOLUTION Si2p CORE-LEVEL STUDY OF THE K/Si(111)-(3 × 1) SURFACE." Surface Review and Letters 09, no. 02 (April 2002): 1235–39. http://dx.doi.org/10.1142/s0218625x02003561.

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The structure of the K/Si (111)-(3 × 1) surface was studied by high-resolution core-level photoelectron spectroscopy. Five surface components were observed in the Si 2p core-level spectra. Compared to the bulk component, three components are shifted to lower and two to higher binding energies. The two components with the lowest binding energies are assigned to the top-layer Si atoms bonded to the K atoms with different configurations. The component with highest binding energy has a contribution from the π-bonded Si atoms of the top layer. The two other components originate from the Si atoms of the second and third layers.

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4

Seibold, Julia C., Sophie Nolden, Josefa Oberem, Janina Fels, and Iring Koch. "The binding of an auditory target location to a judgement: A two-component switching approach." Quarterly Journal of Experimental Psychology 72, no. 8 (February 15, 2019): 2056–67. http://dx.doi.org/10.1177/1747021819829422.

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In a two-component switching paradigm, in which participants switched between two auditory attention selection criteria (attention component: left vs. right ear) and two judgements (judgement component: number vs. letter judgement), we found high judgement switch costs in attention criterion repetitions, but low costs in attention criterion switches. This finding showed an interaction of components. Previous two-component switching studies observed differently emphasised interaction patterns. In the present study, we explored whether the strength of the interaction pattern reflects the strength of the binding of target location and judgement. Specifically, we investigated whether exogenous target location cueing led to weaker binding than endogenous cueing, and whether preparation for ear selection could influence the binding. Attention switches with auditory exogenous target location cues did not affect the component interaction pattern, whereas a prolonged preparation interval led to a more emphasised pattern. Binding between target location and judgement may therefore be rather automatic and may not necessarily require concurrent component processing. Sufficient time for target location switches with long preparation time may activate the previous trial’s episode or facilitate switches of the subsequent judgement.

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5

Golik, V. I., Yu I. Razorenov, V. S. Vagin, and V. I. Lyashenko. "Efficiency of mineral additives to binding component for making hardening mixtures at underground operations." Ferrous Metallurgy. Bulletin of Scientific , Technical and Economic Information 77, no. 6 (June 21, 2021): 643–50. http://dx.doi.org/10.32339/0135-5910-2021-6-643-650.

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For effective operation of mining enterprises, including mines of ferrous metallurgy, supply of quality binding components is necessary to make hardening mixtures for packing of goave, aroused at underground development of hard mineral deposits. Results of the study of compositions based on ash-cement, nepheline, belit-aluminates and lime binding component made of mining and metallurgical production wastes presented. Application of vibro-, mechanical- and electrochemical activation methods to obtain filling mixtures from local low-quality raw materials, as well as activation of binding components were analyzed. A model to evaluate efficiency of binding additives presented. It was shown that decrease of cement consumption by addition of binding components of mineral origin requires perfection of mining processes, first of all, grinding and activation. It was proved, that additions of electric filters ash, nephelines, belit-aluminates and lime, obtained by utilization of current and old tailings to the basic binding component – portland cement – makes it possible to obtain hardening filling mixtures, having high enough strength to apply them at goave packing. Application of the study results makes it perspective for depressed mining and related enterprises to survive under conditions of the forming market.

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6

Jessberger, Nadja, Richard Dietrich, Stefanie Schwemmer, Franziska Tausch, Valerie Schwenk, Andrea Didier, and Erwin Märtlbauer. "Binding to The Target Cell Surface Is The Crucial Step in Pore Formation of Hemolysin BL from Bacillus cereus." Toxins 11, no. 5 (May 20, 2019): 281. http://dx.doi.org/10.3390/toxins11050281.

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A major virulence factor involved in Bacillus cereus food poisoning is the three-component enterotoxin hemolysin BL. It consists of the binding component B and the two lytic components L1 and L2. Studying its mode of action has been challenging, as natural culture supernatants additionally contain Nhe, the second three-component enterotoxin, and purification of recombinant (r) Hbl components has been difficult. In this study, we report on pore-forming, cytotoxic, cell binding and hemolytic activity of recently generated rHbl components expressed in E. coli. It is known that all three Hbl components are necessary for cytotoxicity and pore formation. Here we show that an excess of rHbl B enhances, while an excess of rHbl L1 hinders, the velocity of pore formation. Most rapid pore formation was observed with ratios L2:L1:B = 1:1:10 and 10:1:10. It was further verified that Hbl activity is due to sequential binding of the components B - L1 - L2. Accordingly, all bioassays proved that binding of Hbl B to the cell surface is the crucial step for pore formation and cytotoxic activity. Binding of Hbl B took place within minutes, while apposition of the following L1 and L2 occurred immediately. Further on, applying toxin components simultaneously, it seemed that Hbl L1 enhanced binding of B to the target cell surface. Overall, these data contribute significantly to the elucidation of the mode of action of Hbl, and suggest that its mechanism of pore formation differs substantially from that of Nhe, although both enterotoxin complexes are sequentially highly related.

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7

Zammit, V. A., and C. G. Corstorphine. "Effects of incubation at physiological temperatures on the concentration-dependence of [2-14C]malonyl-CoA binding to rat liver mitochondria." Biochemical Journal 231, no. 2 (October 15, 1985): 343–47. http://dx.doi.org/10.1042/bj2310343.

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Specific binding of [2-14C] malonyl-CoA to rat liver mitochondria was measured at different temperatures and after various periods of time of exposure of the mitochondria to the ligand. Incubation of mitochondria at 37 degrees C in the absence of malonyl-CoA resulted in a decrease in their ability to bind malonyl-CoA at all concentrations tested (up to 55 microM). However, incubation of mitochondria in the presence of malonyl-CoA resulted in the loss of the binding only by a low-affinity component. By contrast, there was an increase in the binding that occurred at low, physiological, concentrations of malonyl-CoA. These differences in the response of the two binding components to incubation conditions were used to obtain quantitative data about their respective saturation kinetics. Evidence was obtained that, whereas the high-affinity component approached saturation hyperbolically with respect to malonyl-CoA concentration, the low-affinity component had sigmoidal characteristics. The concentrations of malonyl-CoA required to half-saturate the two components were 2-3 microM and 30 microM for the high- and low-affinity components respectively. Evidence was also obtained for the involvement of a temperature-dependent transition, that occurred at around 25 degrees C, in the modulation of malonyl-CoA binding to the mitochondria. The possible physiological roles of the two components of malonyl-CoA binding in relation to the regulation of overt carnitine palmitoyltransferase (CPT I) activity in vivo are discussed.

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8

Umei, T., K. Takeshige, and S. Minakami. "NADPH binding component of neutrophil superoxide-generating oxidase." Journal of Biological Chemistry 261, no. 12 (April 1986): 5229–32. http://dx.doi.org/10.1016/s0021-9258(19)57201-5.

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9

Chaoen Xiao, Guangping Zeng, QingChuan Zhang, and Shurong Ning. "Research and Implementation of Distributed Binding SoftMan Component." INTERNATIONAL JOURNAL ON Advances in Information Sciences and Service Sciences 4, no. 23 (December 31, 2012): 565–74. http://dx.doi.org/10.4156/aiss.vol4.issue23.70.

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10

Schade, Arthur L., and Liona Caroline. "An iron-binding component in human blood plasma." Journal of Trace Elements in Experimental Medicine 14, no. 2 (2001): 111–13. http://dx.doi.org/10.1002/jtra.1017.

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11

SERBAN, D., and C. RORDORF-ADAM. "Binding Characteristics of Human Serum Amyloid P Component." Scandinavian Journal of Immunology 25, no. 3 (March 1987): 275–81. http://dx.doi.org/10.1111/j.1365-3083.1987.tb01073.x.

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12

BOUVET, J. P., J. PILLOT, and S. ISCAKI. "Secretory Component-Binding Properties of Normal Serum IgM." Scandinavian Journal of Immunology 31, no. 4 (April 1990): 437–41. http://dx.doi.org/10.1111/j.1365-3083.1990.tb02790.x.

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13

Tempfli, Emmerich, Sascha Zöllner, and Peter Schmelcher. "Binding between two-component bosons in one dimension." New Journal of Physics 11, no. 7 (July 3, 2009): 073015. http://dx.doi.org/10.1088/1367-2630/11/7/073015.

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14

OHLIN, M., and C. BORREBAECK. "Low affinity, antibody binding of an -derived component." FEMS Immunology and Medical Microbiology 13, no. 2 (February 1996): 161–68. http://dx.doi.org/10.1016/0928-8244(95)00122-0.

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15

Zhou, Sizhong, Jiang Xu, and Lan Xu. "Component factors and binding number conditions in graphs." AIMS Mathematics 6, no. 11 (2021): 12460–70. http://dx.doi.org/10.3934/math.2021719.

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<abstract><p>Let $ G $ be a graph. For a set $ \mathcal{H} $ of connected graphs, an $ \mathcal{H} $-factor of a graph $ G $ is a spanning subgraph $ H $ of $ G $ such that every component of $ H $ is isomorphic to a member of $ \mathcal{H} $. A graph $ G $ is called an $ (\mathcal{H}, m) $-factor deleted graph if for every $ E'\subseteq E(G) $ with $ |E'| = m $, $ G-E' $ admits an $ \mathcal{H} $-factor. A graph $ G $ is called an $ (\mathcal{H}, n) $-factor critical graph if for every $ N\subseteq V(G) $ with $ |N| = n $, $ G-N $ admits an $ \mathcal{H} $-factor. Let $ m $, $ n $ and $ k $ be three nonnegative integers with $ k\geq2 $, and write $ \mathcal{F} = \{P_2, C_3, P_5, \mathcal{T}(3)\} $ and $ \mathcal{H} = \{K_{1, 1}, K_{1, 2}, \cdots, K_{1, k}, \mathcal{T}(2k+1)\} $, where $ \mathcal{T}(3) $ and $ \mathcal{T}(2k+1) $ are two special families of trees. In this article, we verify that (i) a $ (2m+1) $-connected graph $ G $ is an $ (\mathcal{F}, m) $-factor deleted graph if its binding number $ bind(G)\geq\frac{4m+2}{2m+3} $; (ii) an $ (n+2) $-connected graph $ G $ is an $ (\mathcal{F}, n) $-factor critical graph if its binding number $ bind(G)\geq\frac{2+n}{3} $; (iii) a $ (2m+1) $-connected graph $ G $ is an $ (\mathcal{H}, m) $-factor deleted graph if its binding number $ bind(G)\geq\frac{2}{2k-1} $; (iv) an $ (n+2) $-connected graph $ G $ is an $ (\mathcal{H}, n) $-factor critical graph if its binding number $ bind(G)\geq\frac{2+n}{2k+1} $.</p></abstract>

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16

Gülke, Irene, Gunther Pfeifer, Jan Liese, Michaela Fritz, Fred Hofmann, Klaus Aktories, and Holger Barth. "Characterization of the Enzymatic Component of the ADP-Ribosyltransferase Toxin CDTa from Clostridium difficile." Infection and Immunity 69, no. 10 (October 1, 2001): 6004–11. http://dx.doi.org/10.1128/iai.69.10.6004-6011.2001.

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ABSTRACT Certain strains of Clostridium difficile produce the ADP-ribosyltransferase CDT, which is a binary actin ADP-ribosylating toxin. The toxin consists of the binding component CDTb, which mediates receptor binding and cellular uptake, and the enzyme component CDTa. Here we studied the enzyme component (CDTa) of the toxin using the binding component of Clostridium perfringens iota toxin (Ib), which is interchangeable with CDTb as a transport component. Ib was used because CDTb was not expressed as a recombinant protein inEscherichia coli. Similar to iota toxin, CDTa ADP-ribosylates nonmuscle and skeletal muscle actin. The N-terminal part of CDTa (CDTa1–240) competes with full-length CDTa for binding to the iota toxin binding component. The C-terminal part (CDTa244–263) harbors the enzyme activity but was much less active than the full-length CDTa. Changes of Glu428 and Glu430 to glutamine, Ser388 to alanine, and Arg345 to lysine blocked ADP-ribosyltransferase activity. Comparison of CDTa with C. perfringens iota toxin and Clostridium botulinumC2 toxin revealed full enzyme activity of the fragment Ia208–413 but loss of activity of several N-terminally deleted C2I proteins including C2I103–431, C2I190–431, and C2I30–431. The data indicate that CDTa belongs to the iota toxin subfamily of binary actin ADP-ribosylating toxins with respect to interaction with the binding component and substrate specificity. It shares typical conserved amino acid residues with iota toxin and C2 toxin that are suggested to be involved in NAD-binding and/or catalytic activity. The enzyme components of CDT, iota toxin, and C2 toxin differ with respect to the minimal structural requirement for full enzyme activity.

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17

Reisenauer, A. M., C. J. Chandler, and C. H. Halsted. "Folate binding and hydrolysis by pig intestinal brush-border membranes." American Journal of Physiology-Gastrointestinal and Liver Physiology 251, no. 4 (October 1, 1986): G481—G486. http://dx.doi.org/10.1152/ajpgi.1986.251.4.g481.

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The intestinal absorption of dietary polyglutamyl folate involves hydrolysis, binding, and transport at the brush-border surface of the enterocyte. We studied the binding of [3H]folic acid ([3H]PteGlu) and the hydrolysis of [14C]pteroyltriglutamate ([14C]PteGlu3) by use of brush-border vesicles prepared from pig jejunal mucosa. [3H] PteGlu associated with the vesicles was not affected by increasing the osmolarity of the incubation solution, verifying that the experiments describe binding and not transport of PteGlu. The binding of [3H]PteGlu was saturable (Kd = 0.08 microM) and pH dependent with maximal binding at pH 5.2. Binding was competitively inhibited by PteGlu3 (Ki = 0.25 microM) and 5-methyltetrahydrofolate (Ki = 0.8 microM) but was not affected by components of the PteGlu molecule. ZnCl2, MgCl2, and MnCl2 enhanced the binding capacity but not the affinity of the binding component for PteGlu. We distinguished the processes of folate binding and hydrolysis by demonstrating differences in metal ion requirements and susceptibilities to various inhibitors. In addition, the binding component and the hydrolytic enzyme had distinct affinities for PteGlu (Ki = 45 microM for PteGlu3 hydrolysis). These data demonstrate pH-dependent, specific, and saturable binding of PteGlu to the intestinal brush-border membrane and suggest that the binding component is separate from the hydrolytic enzyme.

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18

Hattori, Masa-aki, Kazunori Ozawa, and Katsumi Wakabayashi. "Isoelectric properties, lectin binding characteristics and biological activities of neuraminidase-treated rat LH components." Acta Endocrinologica 117, no. 1 (January 1988): 73–79. http://dx.doi.org/10.1530/acta.0.1170073.

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Abstract. The present study was performed to evaluate the different carbohydrate structure of rat LH isoelectric components related to their intrinsic biological activities. Terminal sialic acid residues were essential to the formation of multiple LH components observed in the isoelectric focussing profile, which was proved by their interaction with Ricinus communis agglutinin-120 following neuraminidase treatment, and the conversion of component F (pI, 10.0) to less alkaline components after incubation with liver Golgi membrane fraction in the presence of CMP-NeuNAc. The affinity studies using lentil lectin indicated that component F was not an asialo form of component A (pI 8.4). The serial removal of sialic acid residues from these components led to increases in the steroidogenic activity, owing to increases in the activation of the receptor-adenylate cyclase system. The enhancement of the steroidogenic activity by desialylation was very great in component A'(pI, 8.0) (751% increase), and decreased with increasing pI. It can be concluded that the different biological potencies of intact LH components are attributable principally to terminal sialic acid residues. However, the peripheral chains of asialo oligosaccharides of less alkaline components (pI, 8.0, 8.4) seem to prevent the maximal cellular responses, since their desialylated forms did not attain the maximum activity.

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19

Diedrichsen, Jörn, and Eliot Hazeltine. "Unifying by binding: Will binding really bind?" Behavioral and Brain Sciences 24, no. 5 (October 2001): 884–85. http://dx.doi.org/10.1017/s0140525x01260105.

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The theory of event coding by Hommel et al. proposes that feature binding is a central component of action planning. To evaluate the binding hypothesis, we consider findings from studies of action-perception interference and bimanual movements. We argue that although binding of action features may be a valuable concept, interference from partial feature overlap does not provide a parsimonious account for the observed phenomena.

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20

Dodds, A. W., and S. K. A. Law. "The complement component C4 of mammals." Biochemical Journal 265, no. 2 (January 15, 1990): 495–502. http://dx.doi.org/10.1042/bj2650495.

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Human complement component C4 is coded by tandem genes located in the HLA class III region. The products of the two genes, C4A and C4B, are different in their activity. This difference is due to a degree of ‘substrate’ specificity in the covalent binding reactions of the two isotypes. Mouse also has a duplicated locus, but only one gene produces active C4, while the other codes for the closely related sex-limited protein (Slp). In order to gain some insight into the evolutionary history of the duplicated C4 locus, we have purified C4 from a number of other mammalian species, and tested their binding specificities. Like man, chimpanzee and rhesus monkey appear to produce two C4 types with reactivities similar to C4A and C4B. Rat, guinea pig, whale, rabbit, dog and pig each expresses C4 with a single binding specificity, which is C4B-like. Sheep and cattle express two C4 types, one C4B-like, the other C4A-like, in their binding properties. These results suggest that more than one locus may be present in these species. If this is so, then the duplication of the C4 locus is either very ancient, having occurred before the divergence of the modern mammals, or there have been three separate duplication events in the lines leading to the primates, rodents and ungulates.

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21

Mueller-Ortiz, Stacey L., Audrey R. Wanger, and Steven J. Norris. "Mycobacterial Protein HbhA Binds Human Complement Component C3." Infection and Immunity 69, no. 12 (December 1, 2001): 7501–11. http://dx.doi.org/10.1128/iai.69.12.7501-7511.2001.

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ABSTRACT Mycobacterium tuberculosis and Mycobacterium avium are facultative intracellular pathogens that are able to survive and replicate in mononuclear phagocytes. Human complement component C3 has previously been shown to mediate attachment and phagocytosis of these bacteria by mononuclear phagocytes. In this study, a C3 ligand affinity blot protocol was used to identify a 30-kDa C3-binding protein in M. tuberculosis andMycobacterium smegmatis and a 31-kDa C3-binding protein inM. avium. The C3-binding proteins in M. tuberculosis and M. avium localized to the cell membrane fraction and partitioned to the detergent fraction during Triton X-114 phase partitioning. The C3-binding protein from M. tuberculosis was partially purified using a cation exchange column and was shown to bind concanavalin A. The N terminus and an internal fragment of the partially purified C3-binding protein were subjected to amino acid sequence analysis. The resulting amino acid sequences matched the M. tuberculosis heparin-binding hemagglutinin (HbhA) protein. Recombinant full-length HbhA and the C terminus of HbhA fused to maltose-binding protein, but not recombinant HbhA lacking the C-terminal region, bound human C3. Recombinant full-length HbhA coated on polystyrene beads, was found to enhance the adherence and/or phagocytosis of the coated beads to J774.A1 cells in both the presence and absence of human serum. The presence of complement-sufficient serum increased the adherence of the HbhA-coated beads to the J774.A1 cells in a C3-dependent manner. If HbhA within the bacterial cell membrane functions similarly to isolated HbhA, this protein may enhance the adherence and phagocytosis of M. tuberculosis and M. avium to mononuclear phagocytes through the binding of C3 and interaction with C3 receptors on mononuclear phagocytes.

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22

Hickson, R. C., T. T. Kurowski, T. M. Galassi, D. G. Daniels, and R. J. Chatterton Jr. "Androgen cytosol binding during compensatory overload-induced skeletal muscle hypertrophy." Canadian Journal of Biochemistry and Cell Biology 63, no. 5 (May 1, 1985): 348–54. http://dx.doi.org/10.1139/o85-051.

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This study was undertaken to evaluate whether the increased androgen cytosol binding is an early or later event in the sequence of skeletal muscle hypertrophy induced by surgical overload. Following removal of the synergistic gastrocnemius and soleus muscles, plantaris muscle weights of overloaded hypophysectomized male rats were heavier than those in the controls by 29% at 2 days, 41% at 7 days, 38% at 14 days, and 47% at 35 days. Androgen cytosol receptor binding capacities (femtomoles per milligram protein), determined using a synthetic androgen, [3H]methyltrienolone (R1881), were higher than observed in muscles of controls at all points of muscle enlargement. At high concentrations of labeled ligand, Scatchard analyses became nonlinear and were resolved using a two-component binding model. Receptor capacity of the higher affinity "androgenic component" for methyltrienolone binding in plantaris muscles was lower at 2 days but 60–80% higher at 7, 14, and 35 days in the hypertrophied group than in the control group. The lower affinity "glucocorticoid component" was higher in the overloaded group at all points following surgery. Several glucocorticoids and estradiol-17β competed equally with androgens for methyltrienolone binding. However, when cytosol s were incubated with triamcinolone acetonide to block methyltrienolone binding to glucocorticoid receptors, the androgenic component was highly specific for androgens. These results show that total [3H]methyltrienolone cytosol concentrations increased in parallel with the muscle hypertrophy, yet the individual components of methyltrienolone binding attained greater concentrations in overloaded muscles by an apparently different sequence of events.

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23

Edmonds, S., A. Gibb, and E. Sim. "Effect of thiol compounds on human complement component C4." Biochemical Journal 289, no. 3 (February 1, 1993): 801–5. http://dx.doi.org/10.1042/bj2890801.

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Thiol compounds have been investigated as inhibitors of the covalent binding reaction of human complement protein C4 using Sepharose-C1s as a combined activating and binding surface. o- and p-substituted aminothiophenols are equally effective inhibitors, whereas the m-substituted compound is a less potent inhibitor. The anti-hypertensive drug captopril is also shown to inhibit the covalent binding reaction. A comparison of the effects of these compounds on the covalent binding reaction of isolated C4A and C4B has been made. Results suggest that a Pro-to-Leu substitution in C4B is likely to account for the differences in inhibitory potency of C4B compared with C4A observed with the aromatic inhibitors.

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24

DELIS, ALEX, and VICTOR R. BASILI. "ADA REUSABILITY AND SYSTEM DESIGN ASSESSMENT USING THE DATA BINDING TOOL." International Journal of Software Engineering and Knowledge Engineering 03, no. 03 (September 1993): 287–318. http://dx.doi.org/10.1142/s0218194093000148.

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This paper reports on the development of the data binding tool and its use in Ada source code reusability and software system design assessment. The tool was built around the metric of data bindings. Data bindings fall in the category of data visibility metrics and are used to measure inter-component interactions. Software system components are defined in the context of the Ada language using a flexible scheme. They are used, along with cluster analysis, to present structural configurations of a software system. The clustering technique as well as the tool design and its problems are discussed. The analysis of dendrograms (trees of components produced by the tool) reveals several classes of systems dendrograms and provides a simple mechanism for Ada source code reusability. Finally, the implications of different design methodologies used to develop the test software are discussed and explanations for the several types of dendrogram formulations are given.

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25

Butler, J. DeBrohun, S. Warren Levin, A. Facchiano, and A. B. Mukherjee. "A histidine binding protein ofEscherichia coli: a component of cystine binding protein ofEscherichia coli." Amino Acids 5, no. 1 (1993): 39–50. http://dx.doi.org/10.1007/bf00806191.

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26

TAKAHASHI, Tetsuya, Mitsuo KAWASHIMA, Michiharu KAMIYOSHI, and Katuhide TANAKA. "Mesotocin Binding Component in Various Tissues of the Hen." Japanese poultry science 30, no. 2 (1993): 108–13. http://dx.doi.org/10.2141/jpsa.30.108.

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27

Heegaard, Niels H. H., Peter M. H. Heegaard, Peter Roepstorff, and Frank A. Robey. "Ligand-Binding Sites in Human Serum Amyloid P Component." European Journal of Biochemistry 239, no. 3 (August 1996): 850–56. http://dx.doi.org/10.1111/j.1432-1033.1996.0850u.x.

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28

Di Cera, Enrico. "Negative binding capacity and bistability in one‐component systems." Journal of Chemical Physics 92, no. 5 (March 1990): 3241–43. http://dx.doi.org/10.1063/1.457880.

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29

Ohlin, Mats, and Carl A. K. Borrebaeck. "Low affinity, antibody binding of anEscherichia coli-derived component." FEMS Immunology & Medical Microbiology 13, no. 2 (February 1996): 161–68. http://dx.doi.org/10.1111/j.1574-695x.1996.tb00230.x.

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30

Brown, Kevin D., Raymond P. Zinkowski, Sean E. Hays, and Lester I. Binder. "Actin-binding protein is a component of bovine erythrocytes." Cell Motility and the Cytoskeleton 24, no. 2 (1993): 100–108. http://dx.doi.org/10.1002/cm.970240203.

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31

Christner, R. B., and R. F. Mortensen. "Binding of Human Serum Amyloid P-Component to Phosphocholine." Archives of Biochemistry and Biophysics 314, no. 2 (November 1994): 337–43. http://dx.doi.org/10.1006/abbi.1994.1451.

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32

Comis, A., and S. B. Easterbrook-Smith. "Binding of complement component C1q by rat adipocyte membranes." Molecular Immunology 22, no. 8 (August 1985): 857–61. http://dx.doi.org/10.1016/0161-5890(85)90070-7.

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33

Belcher, John, Yongneng Yao, Anthony J. Berger, Mark L. Mayer, and Albert Lau. "Principal Component Analysis of Glutamate Receptor Ligand Binding Domains." Biophysical Journal 106, no. 2 (January 2014): 805a. http://dx.doi.org/10.1016/j.bpj.2013.11.4412.

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34

Povaliaeva, Alexandra A., Ekaterina A. Pigarova, Anastasia A. Romanova, Larisa K. Dzeranova, Artem Y. Zhukov, and Liudmila Y. Rozhinskaya. "Vitamin D-binding protein: multifunctional component of blood serum." Annals of the Russian academy of medical sciences 76, no. 1 (April 12, 2021): 103–10. http://dx.doi.org/10.15690/vramn1396.

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Vitamin D-binding protein (DBP) was discovered more than half a century ago as a polymorphic serum protein and is currently characterized by a variety of physiological properties. First of all, DBP carries the bulk of vitamin D metabolites circulating in the bloodstream, while albumin is the second most important transport protein, especially in patients with a low concentration of DBP in serum. Since it was discovered that only 12% of the total circulating DBP have occupied steroid binding sites, a vigorous study of other potential biological roles of DBP was initiated: actin utilization, regulation of inflammation and innate immunity mechanisms, fatty acid binding, effects on bone metabolism and participation in the tumor pathogenesis. This review focuses on the main known biological functions of DBP.

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35

Cameron, Caroline E. "Identification of a Treponema pallidum Laminin-Binding Protein." Infection and Immunity 71, no. 5 (May 2003): 2525–33. http://dx.doi.org/10.1128/iai.71.5.2525-2533.2003.

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ABSTRACT Host extracellular matrix (ECM) components represent ideal microbial adhesion targets that many pathogens use for colonization of tissues and initiation of infection. This study investigated the interaction of the spirochete Treponema pallidum with the ECM component laminin. To identify candidate laminin-binding adhesins, the T. pallidum genome was analyzed to predict open reading frames that encode putative outer membrane proteins, as these proteins interact directly with host ECM components. Subsequent recombinant expression of these proteins and analysis of their laminin-binding potential identified one protein, Tp0751, that demonstrated specific attachment to laminin. Tp0751 attached to laminin in a dose-dependent, saturable manner but did not attach to the ECM component collagen type I or IV or to the negative control proteins fetuin or bovine serum albumin. Sodium metaperiodate treatment of laminin reduced the Tp0751-laminin interaction in a concentration-dependent manner, suggesting that oligosaccharides play a role in this interaction. In addition, Tp0751-specific antibodies were detected in serum samples collected from both experimental and natural syphilis infections, indicating that Tp0751 is expressed in vivo during the course of infection. Collectively, these experiments identified Tp0751 as a laminin-binding protein that is expressed during infection and may be involved in attachment of T. pallidum to host tissues.

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36

Yin, J., G. Zhang, and J. Liu. "Genetic Polymorphism of Group-Specific Component/Vitamin-D-Binding Protein Subtypes in Six Populations from North-Eastern China." Anthropologischer Anzeiger 58, no. 2 (July 14, 2000): 193–98. http://dx.doi.org/10.1127/anthranz/58/2000/193.

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37

McMurray, M. M., J. S. Hansen, B. E. Haley, D. J. Takemoto, and L. J. Takemoto. "Interspecies conservation of retinal guanosine 5′-triphosphatase. Characterization by photoaffinity labelling and tryptic-peptide mapping." Biochemical Journal 225, no. 1 (January 1, 1985): 227–32. http://dx.doi.org/10.1042/bj2250227.

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Light-activated hydrolysis of cyclic GMP is achieved through the photoexcitation of rhodopsin, a process which then triggers the replacement of GDP for GTP by a retinal guanosine 5′-triphosphatase referred to as ‘transducin’. The transducin-GTP complex then switches on the phosphodiesterase [Fung, Hurley & Stryer (1981) Proc. Natl. Acad. Sci. U.S.A. 78, 152-156]. The bovine transducin consists of an alpha-subunit (39000 Mr), which is a GTP-binding component, together with a beta-(37000 Mr) and a gamma-subunit (10000 Mr). We have purified retinal transducin from cow, pig, chick and frog. The enzyme specific activities and sodium dodecyl sulphate/polyacrylamide-gel-electrophoretic profiles indicate that this enzyme is similar in all species except the frog. Whereas the bovine, pig and chick transducins consist of major 37000- and 39000-Mr components, that of the frog consists of a single 75000-Mr component. Labelling of the GTP-binding components with the photoaffinity label 8-azidoguanosine [gamma-32P]triphosphate demonstrated that the 37000-Mr components of the cow, pig and chick and the 75000-Mr component of the frog were major GTP-binding components. In addition, peptide maps of radioiodinated tryptic peptides indicate that the frog 75000-Mr protein is highly related to the pig transducin. These results demonstrate evolutionary conservation of retinal transducin and the presence of a higher-Mr, but nonetheless highly conserved form, of transducin in the frog. The relationship of this component to the recently reported rod-outer-segment inhibitor protein [Yamazaki, Stein, Chernoff & Bitensky (1983) J. Biol. Chem. 258, 8188-8194] is discussed.

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38

Hughes, Daniel, Klaas Thoelen, Wouter Horré, Nelson Matthys, Javier Del Cid, Sam Michiels, Christophe Huygens, Wouter Joosen, and Jo Ueyama. "Building Wireless Sensor Network Applications with LooCI." International Journal of Mobile Computing and Multimedia Communications 2, no. 4 (October 2010): 38–64. http://dx.doi.org/10.4018/jmcmc.2010100103.

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Considerable research has been performed in applying run-time reconfigurable component models to the domain of wireless sensor networks. The ability to dynamically deploy and reconfigure software components has clear advantages in sensor networks, which are typically large in scale and expected to operate for long periods in the face of node mobility, dynamic environmental conditions, and changing application requirements. LooCI is a component and binding model that is optimized for use in resource-constrained environments such as Wireless Sensor Networks. LooCI components use a novel event-based binding model that allows developers to model rich component interactions, while providing support for run-time reconfiguration, reflection, and policy-based management. This paper reports on the design of LooCI and describes a prototype implementation for the Sun SPOT. This platform is then evaluated in context of a real-world river monitoring and warning scenario in the city of São Carlos, Brazil.

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39

Wang, Qiaooshi, and Elena Sergeevna Sheremetyeva. "The role of textual binding element “Now about...” in the text structure." Litera, no. 4 (April 2021): 93–103. http://dx.doi.org/10.25136/2409-8698.2021.4.35483.

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The binding element “Now about...” is a means of formation of distant cohesion in the text. It combines the features of grammatical and lexical means of connectivity, which is substantiated by its structure: presence of the permanent grammaticalized component “now about” and substitutable position for preposition. Within the structure of the text, the binding element performs the transition to a new micro-theme as part of the macro-theme, while fulfilling a prospective or a prospective-retrospective function. In terms of prospective function, the formal role is played by grammaticalized component of the binding element, and in terms of prospective-retrospective – both  components; the functions are allocated as follows: free component of the binding element serves as a keyword and fulfills distant retrospective cohesion, while grammaticalized component “now about” due to its semantics, forms the relations of prospection.  The binding element “Now about...” may interact with other logical bonds and also form connectivity, which testifies to its functional self-sufficiency. The acquired results can be applied in lexicographic practice for the development and creation of lexical entries for dictionaries of functional words of the Russian language, in editorial activity, in teaching the syntax of the Russian language, for philological analysis of the text, as well as in teaching Russian as a foreign language.

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40

Hrdina, Pavel D. "Sodium-dependent [3H]imipramine binding in rat hippocampus and its relationship to serotonin uptake." Canadian Journal of Physiology and Pharmacology 65, no. 12 (December 1, 1987): 2422–27. http://dx.doi.org/10.1139/y87-384.

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The relationship of [3H]imipramine recognition sites and serotonergic function was investigated by simultaneously determining the desipramine-defined and sodium-dependent components of [3H]imipramine binding and the serotonin levels and uptake in hippocampus of rats without and with selective lesion of serotonergic neurons with 5,7-dihydroxytryptamine. In control rats, the desipramine-defined [3H]imipramine binding to hippocampal membranes showed a high affinity (Kd = 2 nM) and low affinity (Kd = 31 nM) component. In contrast, the Scatchard analysis of sodium-dependent binding revealed a single class of sites of high affinity (Kd = 1.5 nM). Displacement of sodium-dependent [3H]imipramine binding by cold imipramine resulted in a steep curve best fitted to a one-site model. Sodium-dependent binding of [3H]imipramine at 4 nM concentration represented only about 38% of desipramine-defined binding. 5,7-Dihydroxytryptamine treatment resulted in marked reduction of hippocampal serotonin concentration and uptake without any changes in norepinephrine levels. Virtually only the low affinity component of desipramine-defined [3H]imipramine binding was detected by Scatchard analysis in 5,7-dihydroxytryptamine lesioned rats. The desipramine-defined "specific" [3H]imipramine binding in hippocampi of lesioned rats was decreased by 46%, whereas the sodium-dependent binding was only 18% of that seen in controls. Desipramine-defined specific binding in absence of sodium was not altered by lesion to serotonergic neurons. The results suggest that desipramine-defined specific [3H]imipramine binding may not be appropriate for studying the role of imipramine sites in relation to serotonin neuronal uptake and that determination of sodium-dependent binding components of both [3H]imipramine binding and serotonin uptake should be used in future studies.

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41

Uezato, T., and M. Fujita. "Cytochalasin-B-binding proteins related to glucose transport across the basolateral membrane of the intestinal epithelial cell." Journal of Cell Science 85, no. 1 (September 1, 1986): 177–85. http://dx.doi.org/10.1242/jcs.85.1.177.

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Basolateral membrane vesicles were isolated from mouse enterocytes. The vesicles showed Na+-independent uptake of D-glucose. The uptake was inhibited by cytochalasin B and phloretin with 50% inhibition at 2.0 microM and 25 microM, respectively. 2-Deoxy-D-glucose inhibited D-glucose transport by 50% at 0.5 M. The basolateral membranes bound 13.5 pmol mg protein-1 of 0.1 microM-cytochalasin B. The effects of various monosaccharides on cytochalasin B binding were examined; the strongest inhibitor was 2-deoxy-D-glucose (20–30%). Sodium dodecyl sulphate-polyacrylamide gel electrophoresis of the basolateral membranes labelled with [3H]cytochalasin B revealed two components with Mr values of 52(+/− 2) and 30(X 10(3)). Phloretin and 2-deoxy-D-glucose inhibited the photo-incorporation of [3H]cytochalasin B into these components. While phloretin inhibited the photolabelling of the two components to a similar extent, 2-deoxy-D-glucose seemed to inhibit preferentially that into the 52 X 10(3) Mr component. The similar sensitivity to 2-deoxy-D-glucose of the photolabelling of the 52 X 10(3) Mr component and of D-glucose transport, together with the fact that dithiothreitol removal increased the incorporation into the 52 X 10(3)Mr component and decreased that into the 30 X 10(3) Mr component, seems to suggest that the 52 X 10(3) Mr component is the major glucose transporter of the basolateral membrane.

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42

Yee, Albert G., and C. Daniel Mote. "Forces and Moments at the Knee and Boot Top: Models for an Alpine Skiing Population." Journal of Applied Biomechanics 13, no. 3 (August 1997): 373–84. http://dx.doi.org/10.1123/jab.13.3.373.

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The purpose of this study was to identify regression models to predict moments at the boot top and knee from the force components at the bindings for a sample of skiers. Six subjects skied a slalom course, first with their boots set to the least stiff setting and then with their boots set to the most stiff setting. Six load component dynamometers measured force and moment components at the toe and heel bindings. An electrogoniometer measured ankle flexion. Regression models were developed for the subject sample that predicted quasi-static moment components at the boot top and knee from measurements of ankle flexion and the quasi-static force components at the bindings. Large anterior bending moment was not necessarily accompanied by large ankle flexion, which emphasized that binding designs and standards for injury prevention must account for forces and moments at the sites of potential injury, rather than limiting consideration to boot stiffness or forces at the bindings.

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43

Gauduchon, Valérie, Sandra Werner, Gilles Prévost, Henri Monteil, and Didier A. Colin. "Flow Cytometric Determination of Panton-Valentine Leucocidin S Component Binding." Infection and Immunity 69, no. 4 (April 1, 2001): 2390–95. http://dx.doi.org/10.1128/iai.69.4.2390-2395.2001.

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ABSTRACT The binding of the S component (LukS-PV) from the bicomponent staphylococcal Panton-Valentine leucocidin to human polymorphonuclear neutrophils (PMNs) and monocytes was determined using flow cytometry and a single-cysteine substitution mutant of LukS-PV. The mutant was engineered by replacing a glycine at position 10 with a cysteine and was labeled with a fluorescein moiety. The biological activity of the mutant was identical to that of the native protein. It has been shown that LukS-PV has a high affinity for PMNs (K d = 0.07 ± 0.02 nM, n = 5) and monocytes (Kd = 0.020 ± 0.003 nM,n = 3) with maximal binding capacities of 197,000 and 80,000 LukS-PV molecules per cell, respectively. The nonspecifically bound molecules of LukS-PV do not form pores in the presence of the F component (LukF-PV) of leucocidin. LukS-PV and HlgC share the same receptor on PMNs, but the S components of other staphylococcal leukotoxins, HlgA, LukE, and LukM, do not compete with LukS-PV for its receptor. Extracellular Ca2+ at physiological concentrations (1 to 2 nM) has only a slight influence on the LukS-PV binding, in contrast to its complete inhibition by Zn2+. The down-regulation by phorbol 12-myristate 13-acetate (PMA) of the binding of LukS-PV was blocked by staurosporine, suggesting that the regulatory effect of PMA depends on protein kinase C activation. The labeled mutant form of LukS-PV has proved very useful for detailed binding studies of circulating white cells by flow cytometry. LukS-PV possesses a high specific affinity for a unique receptor on PMNs and monocytes.

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44

CHION CHAN KWO, Chan K. N., and David J. LEAK. "Purification and characterization of two components of epoxypropane isomerase/carboxylase from Xanthobacter Py2." Biochemical Journal 319, no. 2 (October 15, 1996): 499–506. http://dx.doi.org/10.1042/bj3190499.

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Epoxypropane isomerase from Xanthobacter Py2 has been resolved into at least two components (A and B) by ion-exchange chromatography. Both components were required for the degradation of epoxypropane and were purified further. Component A was apparently homohexameric with a subunit Mr of about 44000, and possessed NAD+-dependent dihydrolipoamide dehydrogenase activity and lipoamide reductase activity. It was sensitive to inhibition by o-phenanthroline and the thiol-specific reagents N-ethylmaleimide (NEM) and p-chloromercuribenzoate. Component B was homodimeric with a subunit Mr of 62170 and contained 2 mol·mol-1 FAD. It had an NADPH-dependent lipoamide reductase activity which was sensitive to NEM and p-chloromercuribenzoate. The N-terminal amino acid sequences and monomer sizes of components A and B correspond to those of ORF1 and ORF3 respectively (ORF = open reading frame) of a recently published sequence of a clone which complements mutants unable to degrade epoxypropane. NADPH was found to replace the need for a low-Mr fraction in epoxypropane degradation assays containing components A and B and NAD+. The predicted amino acid sequence of component A (ORF1) has been analysed and shown to contain a potential ADP binding site near the N-terminus and a putative cofactor binding domain near the C-terminus, with sequence similarity to the biotinyl and lipoyl binding domains of biotin-dependent carboxylases and 2-oxoacid dehydrogenases respectively. A reaction mechanism for epoxypropane degradation, incorporating recent evidence for combined isomerization and carboxylation to acetoacetate, is discussed.

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45

Tseng, J., and R. F. Mortensen. "Binding Specificity of Mouse Serum Amyloid P-Component for Fibronectin." Immunological Investigations 15, no. 8 (January 1986): 749–61. http://dx.doi.org/10.3109/08820138609036360.

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46

Kawashima, M., T. Takahashi, T. Yasuoka, M. Kamiyoshi, and K. Tanaka. "A Vasoactive Intestinal Peptide Binding Component in Hen Granulosa Cells." Experimental Biology and Medicine 209, no. 4 (September 1, 1995): 387–91. http://dx.doi.org/10.3181/00379727-209-43912.

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47

Umek, R., A. Friedman, and S. McKnight. "CCAAT-enhancer binding protein: a component of a differentiation switch." Science 251, no. 4991 (January 18, 1991): 288–92. http://dx.doi.org/10.1126/science.1987644.

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48

Sear, Richard P. "Specific protein–protein binding in many-component mixtures of proteins." Physical Biology 1, no. 2 (April 29, 2004): 53–60. http://dx.doi.org/10.1088/1478-3967/1/2/001.

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49

Talley, Kemper, Carmen Ng, Michael Shoppell, Petras Kundrotas, and Emil Alexov. "On the electrostatic component of protein-protein binding free energy." PMC Biophysics 1, no. 1 (2008): 2. http://dx.doi.org/10.1186/1757-5036-1-2.

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50

Mintz, C. S., P. I. Arnold, W. Johnson, and D. R. Schultz. "Antibody-independent binding of complement component C1q by Legionella pneumophila." Infection and immunity 63, no. 12 (1995): 4939–43. http://dx.doi.org/10.1128/iai.63.12.4939-4943.1995.

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