Дисертації з теми "Bacterial studies"
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Leigh, J. A. "Studies on bacterial dehalogenases." Thesis, Nottingham Trent University, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376092.
Повний текст джерелаStenbäck, Anders. "Studies of Experimental Bacterial Translocation." Doctoral thesis, Uppsala University, Department of Surgical Sciences, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5933.
Повний текст джерелаOne of the main obstacles to maintaining patients with short bowel syndrome on parenteral nutrition, or successfully transplanting these patients with a small bowel graft, is the many severe infections that occur. Evidence is accumulating that translocating bacteria from the patient’s bowel causes a significant part of these infections. In this thesis bacterial translocation is studied in a Thiry-Vella loop of defunctionalised small bowel in the rat.
Bacterial translocation to the mesenteric lymph nodes (MLNs) occurs in almost 100% of the rats after three days. No systemic spread of bacteria is observed unless there is additional immunosupression with depletion of Kupffer cells in the liver. However, blocking the function of α/β T cells does not increase the translocation. Removal of MLNs does not either aggravate bacterial translocation in the Thiry-Vella loop model. Conversely, after small bowel transplantation translocating bacteria spread systemically if the MLNs are removed.
The Thiry-Vella loop should also be a suitable model for the testing of potentially translocation-inhibiting substances. Reinforcement of the intestinal barrier with glutamine or phosphatidylcholine proved insufficient in decreasing bacterial translocation. Even selective bowel decontamination with tobramycin failed to abolish bacterial translocation. Thus, it seems that the driving force for translocation in this model is strong regardless of the relatively small trauma of intestinal defunctionalisation.
Flow cytometric studies of the immune cells in the spleen MLNs showed a decrease in MHC class II positive T cells in the MLNs of the Thiry-Vella loop. Concurrently the number of macrophages increased with time as observed by immunohistochemistry. The fraction of MHC class II negative macrophages increased in the spleens of rats treated with glutamine.
In conclusion, the Thiry-Vella loop model offers possibilities of immunological as well as mechanistic studies on bacterial translocation from small intestine.
Chiu, Cecilia P. C. "Crystallographic studies of bacterial sialyltransferases." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/31274.
Повний текст джерелаMedicine, Faculty of
Biochemistry and Molecular Biology, Department of
Graduate
Stenbäck, Anders. "Studies of experimental bacterial translocation /." Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5933.
Повний текст джерелаCordes, Frank Stephan. "Biophysical studies of bacterial pathogenesis." Thesis, University of Oxford, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404113.
Повний текст джерелаBriggs, David Christopher. "Structural studies of bacterial toxins." Thesis, Birkbeck (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414899.
Повний текст джерелаWilkins, G. M. "Studies on bacterial gene transposition." Thesis, University of Warwick, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383407.
Повний текст джерелаLynch, Anthony Simon. "Studies of bacterial DNA topoisomerases." Thesis, University of York, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329651.
Повний текст джерелаDi, Ilio C. "Studies on bacterial glutathione transferase." Thesis, Cranfield University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333472.
Повний текст джерелаHidese, Ryota. "Studies on Bacterial Dihydropyrimidine Dehydrogenases." Kyoto University, 2011. http://hdl.handle.net/2433/142342.
Повний текст джерела0048
新制・課程博士
博士(農学)
甲第16144号
農博第1880号
新制||農||991(附属図書館)
学位論文||H23||N4614(農学部図書室)
28723
京都大学大学院農学研究科応用生命科学専攻
(主査)准教授 栗原 達夫, 教授 小川 順, 教授 阪井 康能
学位規則第4条第1項該当
Holbourn, Kenneth Paul. "Structural studies on bacterial toxins." Thesis, University of Bath, 2006. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436881.
Повний текст джерелаBergström, Niklas. "Structural studies of bacterial carbohydrate antigens with focus on oral commensal bacteria /." Stockholm : Karolinska institutets bibl, 2002. http://diss.kib.ki.se/2002/91-7349-236-1.
Повний текст джерелаChâteau, Maarten de. "Functional, structural and evolutionary studies on a family of bacterial surface proteins." Lund : Dept. of Cell and Molecular Biology, Lund University, 1996. http://catalog.hathitrust.org/api/volumes/oclc/38947242.html.
Повний текст джерелаRozell, Björn. "Immunohistochemical studies of the thioredoxin system." Göteborg : Dept. of Histology, University of Göteborg, 1987. http://catalog.hathitrust.org/api/volumes/oclc/17242526.html.
Повний текст джерелаSarasanandarajah, Sivananthan. "Multiwavelength fluorescence studies of Bacillus bacterial spores." Thesis, University of Canterbury. Physics and Astronomy, 2007. http://hdl.handle.net/10092/3544.
Повний текст джерелаLawrence, Christopher C. "Studies on bacterial proline 4-hydroxylase." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358610.
Повний текст джерелаAgnew, Christopher R. J. "Structural studies of bacterial infection proteins." Thesis, University of Bristol, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.544420.
Повний текст джерелаHill, C. P. "Structural studies on a bacterial ribonuclease." Thesis, University of York, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375429.
Повний текст джерелаAttarataya, Jakrada. "Structural studies of bacterial oxidoreductase enzymes." Thesis, University of Bristol, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.658865.
Повний текст джерелаSilva, Avalos Juan G. (Juan Guillermo). "Isolation, Characterization and Physiological Studies of Cyanide-Utilizing Bacteria." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc278291/.
Повний текст джерелаKanso, Sungwan, and n/a. "Molecular Studies of Bacterial Communities in the Great Artesian Basin Aquifers." Griffith University. School of Biomolecular and Biomedical Science, 2004. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20040219.140509.
Повний текст джерелаKanso, Sungwan. "Molecular Studies of Bacterial Communities in the Great Artesian Basin Aquifers." Thesis, Griffith University, 2004. http://hdl.handle.net/10072/366613.
Повний текст джерелаThesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Biomolecular and Biomedical Sciences
Full Text
Zeng, Muling. "Bacterial cellulose: fabrication, characterization and biocompatibility studies." Doctoral thesis, Universitat Autònoma de Barcelona, 2014. http://hdl.handle.net/10803/284146.
Повний текст джерелаIn March 2011, I started the application of a scholarship from CSC (Chinese Scholarship Council), which cooperated with the Universitat Autònoma de Barcelona (UAB). After about half year, I secured the scholarship and began my doctoral thesis under the supervision of Dr. Anna Roig and Dr. Anna Laromaine. My project assignment was on bacterial cellulose: fabrication, characterization and biocompatibility studies. Bacterial cellulose is a renewable polysaccharide, which is produced by some types of bacteria in nature. It presents remarkable chemical and physical properties, including high chemical purity and crystallinity, nano-scale fibre network, porosity, high water absorption capacity and mechanical strength. Bacterial cellulose is being used for a wide variety of commercial applications, for example textiles, cosmetics, food products and other technical areas. Furthermore, bacterial cellulose is also biocompatible with excellent biological affinity and biodegradability, which is drawing immense attention from the bio and medical area researchers. The objective of my thesis was to learn how to produce bacterial cellulose films and find strategies to control their properties. A second objective was to developed methods to fabricate nanocomposites based on bacterial cellulose. The final objective was related to prove the biocompatibility of the in-house produced bacterial cellulose films and to be able to use them as three-dimensional scaffolds for cell in-growth. In this way setting up a platform that will allow us to study the interaction of cells and nanoparticles in a realistic 3D environment. During the first year, a lab set-up was successfully built to produce bacterial cellulose from two bacterial strains and three methods of drying were accessed to dry the thin films; at room temperature, freeze drying and supercritical drying. Moreover, the full characterization of bacterial cellulose films was accomplished: their porosity, transparency, water absorption capacity and mechanical properties were tuned by selecting the bacterial strain and the drying method. In the second year, bacterial cellulose composited with nanoparticles as novel functional cellulose materials were synthesized by microwave-assisted method. This method is efficient and fast to form a homogenous conformal and controllable coating of nanoparticles on the bacterial cellulose films. By drying the cellulose films using different routes, the final amount of the nanoparticles content in the composites can be controlled. Furthermore, those films were patterned with hydrophobic/hydrophilic domains and selectively anchored nanoparticles to create more complex and functional cellulose composites. During the last year, an investigation of the biocompatibility of the bacterial cellulose films in vitro was performed. Although bacterial cellulose is generally considered non-cytotoxic material, its biocompatibility as a major requirement for the use in biological and medical applications has not been fully evaluated. Furthermore, an improved 3D bacterial cellulose scaffold was fabricated. The thesis is organized into six chapters. Chapter 1 provides an introduction to bacterial cellulose. Chapter 2 describes a detailed description of the fabrication of bacterial cellulose films (BCFs). Chapter 3 focuses on the synthesis of functional bacterial cellulose composites incorporating nanoparticles. Chapter 4 presents the studies of bacterial cellulose biocompatibility as 2D and 3D scaffold for cell studies in vitro. Chapter 5 lists the main conclusions derived from the present thesis and some suggestions for the future work. Chapter 6 gathers information about the author and the publications during the Ph.D. studies.
Noursadeghi, Mahdad. "Studies of innate immunity to bacterial infection." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406424.
Повний текст джерелаBond, Peter J. "Simulation studies of bacterial outer membrane proteins." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419258.
Повний текст джерелаOnakunle, Ojo Adegboyega. "Studies on the enantioselectivity of bacterial lactonases." Thesis, University of Kent, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362189.
Повний текст джерелаGibson, Kevin J. C. "Structural and biochemical studies on bacterial lipoglycans." Thesis, University of Newcastle Upon Tyne, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.397343.
Повний текст джерелаConroy, Matthew James. "NMR studies of bacterial light-harvesting complexes." Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298888.
Повний текст джерелаTrambaiolo, Daniel Marco. "Crystallographic studies of bacterial cell division proteins." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611977.
Повний текст джерелаLloyd, Diarmuid Padraig. "Microscopic studies of surface growing bacterial populations." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/10509.
Повний текст джерелаKawasaki, Haruhiko. "STUDIES ON PLASMIDS DETERMINING BACTERIAL HALOACETATE DEHALOGENASES." Kyoto University, 1985. http://hdl.handle.net/2433/78183.
Повний текст джерелаRamesar, Rajkumar Sewcharan. "Developmental genetic studies on Thiobacillus ferrooxidans." Doctoral thesis, University of Cape Town, 1988. http://hdl.handle.net/11427/26235.
Повний текст джерелаPrayitno, Slamet Budi. "Studies of bacteria causing prawn disease in Indonesia with special emphasis on luminous bacterial disease." Thesis, Bangor University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.483433.
Повний текст джерелаMcClellan, J. A. "Studies on Escherichia coli-mutabile." Thesis, University of Leeds, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355195.
Повний текст джерелаChoudhury, Hassanul Ghani. "Structural and functional studies of bacterial detoxification mechanisms." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/39387.
Повний текст джерелаDiab, Asim Eltayeb. "Experimental bacterial meningitis : studies on immunopathogenesis and immunoregulation /." Stockholm, 1998. http://diss.kib.ki.se/1998/91-628-3008-2.
Повний текст джерелаTanabe, Mikio. "Structural, functional and immunological studies of bacterial transporters." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428677.
Повний текст джерелаQua, A. R. "Anti-bacterial structure-function relationship studies on melittin." Thesis, Queen's University Belfast, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419557.
Повний текст джерелаCheesman, Myles Richard. "Spectroscopic studies of nickel ions in bacterial proteins." Thesis, University of East Anglia, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327824.
Повний текст джерелаCox, Charles. "Structural and functional studies of bacterial mechanosensitive channels." Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/44553/.
Повний текст джерелаDuman, Ramona Elena. "Structural studies of bacterial Lon ATP-dependent proteases." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609086.
Повний текст джерелаBack, Catherine R. "Structural and functional studies of oral bacterial adhesins." Thesis, University of Bristol, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.650102.
Повний текст джерелаWalford, Gillian. "NMR and conformational studies of bacterial polysaccharide antigens." Thesis, University of Cambridge, 1993. https://www.repository.cam.ac.uk/handle/1810/272377.
Повний текст джерелаCosta, Jill Bonham. "Structural studies of some viscous, acidic bacterial exopolysaccharides /." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487687959968165.
Повний текст джерелаBreuleux, Claire Emilie. "Studies on bacterial lung infections in cystic fibrosis." Thesis, Aston University, 2000. http://publications.aston.ac.uk/12359/.
Повний текст джерелаMalasarn, Davin Sternberg Paul W. "Molecular and environmental studies of bacterial arsenate respiration /." Diss., Pasadena, Calif. : California Institute of Technology, 2007. http://resolver.caltech.edu/CaltechETD:etd-02232007-132917.
Повний текст джерелаMalik, A. N. "Genetic studies with Pseudomonas syringae pathovar pisi." Thesis, University of Greenwich, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.354390.
Повний текст джерелаHill, Russell. "Gene cloning studies in two nocardioform bacteria." Doctoral thesis, University of Cape Town, 1988. http://hdl.handle.net/11427/21896.
Повний текст джерелаNocardioforms are Gram-positive, aerobic actinomycetes and are a metabolically diverse group which produce antibiotics, useful enzymes, are important in the biotransformation of organic compounds and the decomposition of organic wastes and are important medically. A gene cloning vector designated pLR591 was constructed from the broad host range, multicopy Streptomyces plasmid pIJ702 and the positive selection Escherichia coli plasmid pEcoR251. This plasmid has useful features for the construction of actinomycete genomic libraries. Cloning of DNA into the unique Bg1II endonuclease site of pLR591 inactivated the lethal EcoRI gene derived from pEcoR251, thereby selecting for recombinant plasmids containing inserted DNA. The thiostrepton resistance gene derived from pIJ702 was shown to be functional in Streptomyces lividans enabling selection of recombinant pLR591 plasmids containing foreign DNA in S. lividans. The vector pLR591 therefore functions as a positive selection Streptomyces-E. coli shuttle vector facilitating construction of actinomycete genomic libraries in E. coli and subsequent transfer of recombinant plasmids into S. lividans.
Yang, Dong. "Structural studies of terpenoid biosynthesis and bacterial cell division." [College Station, Tex. : Texas A&M University, 2006. http://hdl.handle.net/1969.1/ETD-TAMU-1737.
Повний текст джерелаPanjikar, Santosh. "Crystallographic studies of bacterial single stranded DNA-binding proteins." [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=964154366.
Повний текст джерела