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Статті в журналах з теми "Association de patients"

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Автор: Grafiati

Опубліковано: 6 липня 2024

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1

Kumar K N, Santhosh. "The Association of Diastolic Dysfunction in Patients with Hypoalbuminemia." International Journal of Science and Research (IJSR) 12, no. 6 (June 5, 2023): 218–21. http://dx.doi.org/10.21275/sr23530133220.

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2

Nandy, Anirban, and Samal Jakobsen. "Patent Foramen Ovale (PFO) and Association with Cryptogenic Stroke in Young Patients." International Journal of Neurology and Neurosurgery 10, no. 2 (2018): 121–23. http://dx.doi.org/10.21088/ijnns.0975.0223.10218.9.

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3

Bardak, Simge, Sibel Sarı, Mehmet Horoz, Kenan Turgutalp, Ebru Gök Oğuz, Türkay Özcan, Arzu Kanık, Serap Demir, and Ahmet Kıykım. "Association Between New Cardiac Biomarkers and Cardiovascular Abnormalities in Asymptomatic Hemodialysis Patients." Turkish Nephrology Dialysis Transplantation 26, no. 01 (January 13, 2017): 60–66. http://dx.doi.org/10.5262/tndt.2017.1001.10.

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4

Salaria, Nitin Singh, and Malhar Vyas. "Association of Diabetic Retinopathy and Lipid Profile in Diabetic Patients in Mathura District." Asian Journal of Medical Research 8, no. 1 (March 2019): OT01—OT05. http://dx.doi.org/10.21276/ajmr.2019.8.1.ot1.

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5

Karatas, Ercan, Lacin Aksoy, and Ersin Ozaslan. "Association of Early Favipiravir Use with Reduced COVID-19 Fatality among Hospitalized Patients." Cancer Research and Cellular Therapeutics 5, no. 4 (August 30, 2021): 01–08. http://dx.doi.org/10.31579/2640-1053/093.

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Background: The antiviral agent favipiravir is an RNA-dependent RNA polymerase (RdRp) inhibitor. Materials and Methods: We examined patients with a clinical, laboratory, and radiological diagnosis of severe coronavirus disease 2019 (COVID-19) pneumonia. We investigated the effect of administering enteral favipiravir at a 2 × 1,600 mg loading dose and 2 × 600 mg maintenance dose for 5 days in addition to the standard COVID-19 treatment. Results: In total, 180 patients, who were hospitalized at the Istanbul Tuzla State Hospital and received favipiravir treatment between March 20, 2020 and May 30, 2020, were examined. Of these, 47 patients died. Thirty-three of the patients who died were aged over 65 years (70%), indicating that fatality was higher in elderly patients. Most of those who died had at least one comorbidity. Of the 101 patients who initiated favipiravir within ≤3 days of hospitalization, 17 died (17%). Of the 79 patients who initiated favipiravir after >3 days of hospitalization, 30 died (38%) (P = 0.002). Conclusion: We found that initiation of favipiravir within the first 72 h after the onset of disease symptoms reduced fatality in patients with COVID-19.

6

Choudhury, Saswati Sanyal, Lokeshwari K, and Gokul Chandra Das. "Association between hyperhomocysteinemia and adverse obstetric outcome in patients with bad obstetric history." New Indian Journal of OBGYN 8, no. 1 (July 2021): 19–22. http://dx.doi.org/10.21276/obgyn.2021.8.1.5.

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7

Mohan, Sandya, Vibhaavari Venkatesh, Cynthia Ganesan, Supriya Velraja, and Rajkumar Rajkumar. "Association of Parosmia and nutritional status in Post COVID Patients using PAST TOOL." Indian Journal Of Science And Technology 16, no. 35 (September 26, 2023): 2807–12. http://dx.doi.org/10.17485/ijst/v16i35.1106.

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8

Torjesen, I. "Patients Association deems hospitals' care of older patients "unacceptable"." BMJ 343, no. 10 3 (November 10, 2011): d7321. http://dx.doi.org/10.1136/bmj.d7321.

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9

McMahon, John W. "American Medical Association and patients' autonomy." Lancet 375, no. 9720 (March 2010): 1078. http://dx.doi.org/10.1016/s0140-6736(10)60471-0.

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10

Mohan, Vijaya, and Vishwanath VN. "The Association between Serum Lipid Profile and Nephropathy in Type 2 Diabetes Mellitus Patients." Academia Journal of Medicine 2, no. 1 (July 10, 2019): 18–21. http://dx.doi.org/10.21276/ajm.2019.2.1.6.

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11

VN, Karan, and Vijaya Mohan. "The Association between Serum Lipid Profile and Retinopathy in Type 2 Diabetes Mellitus Patients." Academia Journal of Medicine 2, no. 1 (July 10, 2019): 22–25. http://dx.doi.org/10.21276/ajm.2019.2.1.7.

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12

KazemiJahromi, Mitra. "The Association of Liver Enzymes with Disease Severity in PCR positive COVID-19 Patients." Diabetes & Obesity International Journal 6, no. 3 (2021): 1–8. http://dx.doi.org/10.23880/doij-16000245.

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Introduction: This study aimed to examine the relationship between liver enzymes and severity of COVID-19. Furthermore, patients with clinical diagnosis (PCR negative) and patients with definitive laboratory diagnosis (PCR positive) of COVID-19 were compared in terms of disease severity. Method: This cross-sectional study enrolled 158 patients with COVID-19 admitted based on chest CT scan findings to the COVID-19 ward of Shahid Mohammadi Hospital, affiliated with Hormozgan University of Medical Sciences (Iran).Reversetranscriptase polymerase chain reaction (RT-PCR) test was performed for all the patients, who were accordingly divided into groups of PCR negative COVID-19 with clinical diagnosis, and COVID-19 with definitive laboratory diagnosis. Results: The results indicated a significant elevation of AST (Aspartate transaminase) and Alanine transaminase (ALT) in the PCR positive group compared to the PCR negative group (p = 0.02, p = 0.04, respectively). The results also showed a correlation between AST level and COVID-19 severity (p < 0.01, OR = 2.06). Moreover, a significant correlation was observed between ESR and the levels of AST and ALT (r = 0.24 for AST, r = 0.47 for ALT). Conclusion: AST and ALT significantly increased in the PCR positive group compared to the PCR negative group, and AST was correlated with COVID-19 severity. Furthermore, a significant correlation was observed between ESR and the levels of AST and ALT. Therefore, COVID-19 involves liver both directly and through the inflammatory system.

13

Köse, Esra, Kenan Turgutalp, Ahmet Kıykım, and Fatma Çelik. "The Association Between Feeding Habits, Nutritional Parameters and Quality of Sleep in Hemodialysis Patients." Turkish Nephrology Dialysis Transplantation 23, no. 01 (January 21, 2014): 14–19. http://dx.doi.org/10.5262/tndt.2014.1001.04.

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14

Itam, Ako Hogan, Yeonun Mba Ogarekpe, Bassey Edem, Abdulhakeem Rotimi Agboola, Henry Chima Okpara, and Enembe Oku Okokon. "Association between Serum Calcium Concentration and Glycated Haemoglobin in Type II Diabetic Nigerian Patients." BIOMED Natural and Applied Science 02, no. 03 (December 10, 2022): 25–32. http://dx.doi.org/10.53858/bnas02032532.

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Background: Diabetes is a metabolic disease that affects key biochemical parameters in the body. The study was carried out to evaluate the serum calcium concentration and the relationship between serum calcium and glycosylated haemoglobin in type 2 diabetics. Methods: A total of 126 subjects consisting of 63 Diabetic patients and 63 controls participated in this study. Serum calcium and glycosylated haemoglobin concentrations were measured. Fasting blood sugar was also measured. Total calcium was measured using colorimetric determination of plasma total calcium by the o-cresolphthalein o-complexone (CPC) assay principle. Plasma albumin was determined using Bromocresol green (BCG) method, and thus corrected calcium was deduced. Glycosylated haemoglobin (HbA1C) was estimated using an ion-exchange chromatographic method. A semi-structured questionnaire was used for data collection. Results: The mean serum calcium levels of diabetics compared to non-diabetics did not differ statistically even though that of diabetics was in the lower range of normal. There was no statistically significant difference (p=0.099) between the mean serum calcium levels of diabetic patients who had glycosylated haemoglobin values below 6.5 (2.26 mmol/l±0.07) and diabetic patients who had glycosylated haemoglobin values above 6.5 (2.17mmol/l±0.09). Surprisingly, there was a weak positive correlation between glycosylated haemoglobin levels above 6.5 and serum calcium levels (p=0.087) and HbA1C below 6.5 correlated negatively albeit weakly with serum calcium levels though they were both insignificant. Socio-demographic data show that more females were diabetic. Conclusion: Overall, the study reveals that mean serum calcium concentrations in diabetic and non-diabetic patients are not different and this may be due to good blood glucose control in these diabetic patients

15

Vadodariya, Namrata, and Harsha Jivarajani. "Association of Ventilator Associated Pneumonia with Various Risk Factors in Patients at Ahmedabad, Gujarat." Indian Journal of Emergency Medicine 4, no. 2 (June 15, 2018): 93–98. http://dx.doi.org/10.21088/ijem.2395.311x.4218.4.

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Background and Aim: Ventilator associated pneumonia (VAP) is a common complication in critically ill patient affecting 9 to 27% of all critically ill patients. We have done the study of ventilator associated pneumonia (VAP) with various risk factors like age, sex, duration of ventilation, airway access, various organisms and their culture and sensitivity to various antibiotics and comorbid conditions associated with ventilator associated pneumonia. Material and Methods: The present study was conducted in our Medical ICU of Civil Hospital during period from November 2009 to November 2011. It includes 100 cases of mechanically ventilated patients of age more than 15 years. VAP was defined as the occurrence of a new and persistent radiographic infiltrate in conjunction with positive endotracheal aspirate culture. A cut off of 7 days of mechanical ventilator was used to distinguish patient with early nset VAP from those with late onset VAP. Risk factors like age, sex, duration of mechanical ventilation and comorbid conditions like COPD, stroke, ischemic heart disease were studied. Results: Most common comorbid state associated with mechanical ventilatory support was COPD and 72.72% patients with COPD developed VAP. incidence of VAP was highest with reintubation (70%) followed by tracheostomy (30%) and non-invasive ventilation (20%). most common organism for VAP was Pseudomonas with 37.5% incidence, followed by Staphylococcus Aureus (16.66%), Klebslia (16.66%), Conclusion: Ventilator associated pneumonia is an important cause of mortality in ICU patients. Most important risk factors for development of VAP include age >60 years, presence of co-morbid illnesses, re intubations, duration of ICU stay.

16

Kondvilkar, Siddhi, Lokesh H M, Safa S Razi, Tanvi Patil, and Saipreethi Gundareddy. "Association of Intraocular Pressure with HbA1C Levels in Patients with Type 2 Diabetes Mellitus." International Journal of Science and Research (IJSR) 13, no. 5 (May 5, 2024): 479–82. http://dx.doi.org/10.21275/sr24507010859.

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17

Hashmi, Sayed Fasih Ahmed, and Ambreen Haidar. "VITAMIN D ASSOCIATION." Professional Medical Journal 22, no. 10 (October 10, 2015): 1316–20. http://dx.doi.org/10.29309/tpmj/2015.22.10.986.

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OBJECTIVE: The target of this study to focus, vitamin D level is the significant riskfactors for the patients with cardio vascular disease at Liaquat University Hospial Hyderabad /Jamshoro. Materialand Methods: This observational study was done at cardiology departmentof Liaquat University Hospital Hyderabad. All the cases with history of congenital heart disease,pregnancy, malignancy, renal failure and chronic liver disease, were excluded from the study.Complete medical history was taken, and major risk factors of the cardiovascular diseaseincluding, diabetes, smoking, family history, hypertension, hypercholestremia, dyslipidemiaand history of alcohol consumption and others were documented. Serum VD level was testedby blood samples from research laboratory of Liaquat Medical hospital Hyderabad, and all theresults were noted on the Performa according to the risk factors. Consequences of VD levelwere arranged by criteria, that’s taken from the study of Satish Karur etal.10 Results: Total 100patients were incorporated in the study with the mean age of 48.2+ 12.4. Male were found inthe majority. According to distribution of heart disease of his study ischemic heart disease hadnoted commonest58%. In the hypertensive patients VD deficiency had noted in 39. 63%. Insmoker patients VD deficiency was noted in 52.77%. In patients with hypercholestremia 50.0%,Alcoholic patients were found with deficiency of VD were 50.0%. In patients with obesity 57.14%.In the diabetic patients deficiency 15.0%, insufficiency 50.0% and sufficiency was seen 35.0%.In the Patients of dyslipidemia deficiency5.0%, insufficiency 50.0% and sufficiency was seen45.0%. Patients with family history of cardiovascular disease having deficiency 25.0% of thecases, insufficiency 12.50% while sufficiency in 62.50% in the cases. Conclusion: In this studywe concluded that VD deficiency in one of the major risk factor for cardiovascular disease;its possible association was found in this study with many risk factors of heart diseases. Likeour study there is very need of experimental and prospective more studies, to find out themechanism undergoing increasing cardiovascular risk, and prevent the cardiovascular disease.

18

Bacqué, M. F. "France Lymphome Espoir : une association de patients pour des patients." Psycho-Oncologie 6, no. 4 (November 25, 2012): 260. http://dx.doi.org/10.1007/s11839-012-0398-7.

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19

Amiri, Mina, Fahimeh Tehrani, Razieh Bidhendi-Yarandi, Samira Behboudi-Gandevani, Fereidoun Azizi, and Enrico Carmina. "Relationships Between Biochemical Markers of Hyperandrogenism and Metabolic Parameters in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis." Hormone and Metabolic Research 51, no. 01 (January 2019): 22–34. http://dx.doi.org/10.1055/a-0806-8281.

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AbstractWhile several studies have documented an increased risk of metabolic disorders in patients with polycystic ovary syndrome (PCOS), associations between androgenic and metabolic parameters in these patients are unclear. We aimed to investigate the relationships between biochemical markers of hyperandrogenism (HA) and metabolic parameters in women with PCOS. In this systematic review and meta-analysis, a literature search was performed in the PubMed, Scopus, Google Scholar, ScienceDirect, and Web of Science from 2000 to 2018 for assessing androgenic and metabolic parameters in PCOS patients. To assess the relationships between androgenic and metabolic parameters, meta-regression analysis was used. A total number of 33 studies involving 9905 patients with PCOS were included in this analysis. The associations of total testosterone (tT) with metabolic parameters were not significant; after adjustment for age and BMI, we detected associations of this androgen with low-density lipoproteins cholesterol (LDL-C) (β=0.006; 95% CI: 0.002, 0.01), high-density lipoproteins cholesterol (HDL-C) (β=–0.009; 95% CI: –0.02, –0.001), and systolic blood pressure (SBP) (β=–0.01; 95% CI: –0.03, –0.00). We observed a positive significant association between free testosterone (fT) and fasting insulin (β=0.49; 95% CI: 0.05, 0.91); this association remained significant after adjustment for confounders. We also detected a reverse association between fT and HDL-C (β=–0.41; 95% CI: –0.70, –0.12). There was a positive significant association between A4 and TG (β=0.02; 95% CI: 0.00, 0.04) after adjustment for PCOS diagnosis criteria. We also found significant negative associations between A4, TC, and LDL-C. Dehydroepiandrosterone sulfate (DHEAS) had a positive association with LDL-C (β=0.02; 95% CI: 0.001, 0.03) and a reverse significant association with HDL-C (β=–0.03; 95% CI: –0.06, –0.001). This meta-analysis confirmed the associations of some androgenic and metabolic parameters, indicating that measurement of these parameters may be useful for predicting metabolic risk in PCOS patients.

20

Akhter, Hachina, and Ferdousi Begum. "Association of Clinical Presentation at Different Stages of Carcinoma Cervix." Annals of International Medical and Dental Research 9, no. 3 (June 2023): 74–81. http://dx.doi.org/10.53339/aimdr.2023.9.3.10.

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Background: Cancer cervix is the most common cancer in women in developing countries where screening facilities are inadequate. The incidence of cervical cancer is steadily declining in the developed world. The rate of cervical cancer is decreasing day by day due to their awareness of cervical cancer, especially its risk factors, and undertaking measure like routine screening tests. It may present with vaginal bleeding but symptoms may be absent until the cancer is in its advanced stage. This study aimed to analyze the association of clinical presentation at different stages of carcinoma cervix. Material & Methods: This descriptive study was conducted in Chittagong Medical College Hospital, taking 100 randomly selected patients of carcinoma cervix over one year (July 2019 to June 2020). The research protocol was approved by the research committee (Local Ethical committee). Informed written consent was taken from each patient. Results: Among the study subjects, most of the respondents (32, 32.0%) belonged to 51-60 years old followed by (24, 24.0%) 41-50 years and >60 years of age. Most (76, 76.0%) of the patients presented with blood-stained vaginal discharge. Significant numbers of the patient presented with foul smelling per vaginal discharge (72, 72.0%) and post-coital bleeding (68, 68.0%). Only 8% of the patients had haematuria signifying the advanced stage of the disease. Most of the patients about 72.0% sought medical advice within one year of developing symptoms. 56.0% of patients were menopausal, only 20.0% of patients had regular menstruation, and 24.0% of patients had irregular menstruation. 24.0% of patients had metrorrhagia and 2.0% of patients had dysmenorrhoea. Some degree of anemia was present in almost all patients. Only 16.0% of the patients had severe anemia 6.0% of the patients had dependent edema and 4.0% had lymphadenopathy. Most of the patients had cauliflower-type (54.0%) lesions in the cervix followed by 36.0% of patients who had the ulcerative type of growth in the cervix. Among the respondents, 96.0% of the patients had squamous cell carcinoma and only 4% had adenocarcinoma. Most (44, 44.0%) of the patients presented in the hospital with stage II ca cervix, followed by stage III (40, 40.0%). Conclusion: Most common presentation was blood-stained per-vaginal discharge, followed by foul-smelling per-vaginal discharge and post-coital bleeding. All the patients were clinically anemic, some showed severe anemia. The majority of the patient in this series showed a cauliflower-like lesion, followed by an ulcerative lesion. Among all patients majority (96.0%) had squamous cell carcinoma and the remaining had adenocarcinoma. Most of the patients presented in the hospital with stage II ca cervix, followed by stage III.

21

Gahlawat, Rachana, and Dinesh Narain Saksena. "Association of Serum Lipids Levels in Patients of Type 2 Diabetic Retinopathy and Without Retinopathy." Asian Journal of Medical Research 8, no. 2 (June 2019): OT04—OT08. http://dx.doi.org/10.21276/ajmr.2019.8.2.ot2.

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22

Parakhina, Viktoriya, Yelena Mikhailovna Laryushina, and Olga Ponamareva. "Association between Endocan, PAI-1 and intima media thickness in patients with high diabetes risk." Bulletin of the Karaganda University. “Biology, medicine, geography Series” 106, no. 2 (June 30, 2022): 134–44. http://dx.doi.org/10.31489/2022bmg2/134-144.

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There is no information in the literature on the ratio of the concentrations of Endocan, PAI-1, and intima media thickness (IMT) in patients with high diabetes risk. This study aims to investigate the relationships between endothelial dysfunction biomarkers: Endocan, Plasminogen Activator Inhibitor-1(PAI-1), insulin resistance (IR) indicators, and IMT of the common carotid artery (CCA) in patients with risk of type 2 diabetes mellitus (T2DM). A case-control study was held, including 184 individuals, aged from 18 to 65 years. According to FINDRISC scale, patients were divided into 2 groups: Group 1 (n = 138) — low risk of T2DM (<12 points) and Group 2 (n = 46) high risk of T2DM (>12 points). IMT more than 0.9 mm on ultrasound considered as an atherosclerosis. Significant differences were found when studying the level of Endocan, PAI-1 biomarkers with their predominance in the group of patients with a high risk of T2DM; concentrations of Endocan comprised (mean±SD) 1698.2±576.2 pg/ml; p=0.01; PAI-1–32307.15±19947.12 pg/ml; p=0.05 to compare with low risk of T2DM. In addition to, mean values of IMT prevailed in patients in the group with a high diabetes risk and comprised right IMT CCA-0.90±0.15 mm; p = 0.05, left IMT CCA0.91±0.14 mm; p=0.02. Interrelations between Endocan, PAI-1, and IMT CCA have been determined by correlation analysis. These findings indicate that in patients with high diabetes risk the elevations of the Endocan, PAI-1 is associated with a subclinical atherosclerosis. Furthermore, both biomarkers Endocan and PAI-1 has been demonstrating significant correlation with insulin, IR-HOMA index, С-peptide, HbA1c, and fasting glucose in patients with high risk of T2DM. We found significant relationships between the ED biomarkers with IMT and IR in patients with high risk of T2DM. We suggest that rising of IR leads to Endocan and PAI-1 elevation, subclinical atherosclerosis and thereby increase ED and cardiovascular risk in these patients.

23

TAM, Hamid. "Association of Methylene Tetrahydrofolate Reductase Gene A1298C (Rs1801131) Polymorphism with Myocardial Infarction among Sudanese Patients." Haematology International Journal 5, no. 2 (2021): 1–6. http://dx.doi.org/10.23880/hij-16000192.

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Background: Myocardial infarction (MI) is among the leading causes of mortality worldwide. Variations in folate metabolism including genetic polymorphisms in the key metabolic enzymes had showed influences in the MI process. Objectives: To determine whether the C1298A transition in the Methylene Tetrahydrofolate Reductase ( MTHFR ) gene is associated with increased risk for MI among Sudanese patients. Material and methods: This is a hospital based case control study in which a total of 140 Sudanese subjects were enrolled, 70 patients with myocardial infarction and 70 age- and sex matched healthy volunteers as a control group. Genomic DNA was extracted by (QIA gene, Korea) kits and the SNPs genotypes were determined using polymerase chain reaction followed by restriction fragment length polymorphism (PCR- RFLP). Data of this study were collected using a structured interview questionnaire and analyzed by statistical package for social sciences (version 21). Results: The frequency of the AA genotype was higher in the patients group compared with control (96%, 71% respectively); while the AC genotype was higher in the control (20%, 5% respectively), while the CC genotype was not observed in this study population. The frequencies of A and C alleles were 0.68 and 0.02 respectively in MI patients while frequencies were 0.60 and 0.10 respectively in the control group. No statistically significant association was observed between MTHFR genotypes and MI (P. values = 0.4 and 0.1 for AA and AC genotypes respectively). Conclusion: In this study population, the A1298C MTHFR polymorphism is not associated with the risk of MI among the Sudanese population.

24

Singh, Luxmi, Lubna Ahmed, Swati Yadav, Pragati Garg, and B. B. Lal. "DIABETIC MACULAR EDEMA IN ASSOCIATION WITH DIABETIC RETINOPATHY IN PATIENTS OF TYPE 2 DIABETES MELLITUS." ERA'S JOURNAL OF MEDICAL RESEARCH 5, no. 1 (June 2018): 06–08. http://dx.doi.org/10.24041/ejmr2018.55.

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25

Merin, Jilu Ji, Athira PC, and Sujith Varma. "A STUDY ON ASSOCIATION OF DEPRESSION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS HAVING SMOKING HABIT." INDIAN RESEARCH JOURNAL OF PHARMACY AND SCIENCE 4, no. 2 (June 2017): 1045–50. http://dx.doi.org/10.21276/irjps.2017.4.2.13.

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26

Naga Teja Sri, G. "Prevalence of Stroke in Post COVID-19 Patients and their Association with Comorbidities: Literature Review." International Journal of Science and Research (IJSR) 12, no. 6 (June 5, 2023): 1188–93. http://dx.doi.org/10.21275/sr23610002408.

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27

COUSTET, BAPTISTE, MATTHIEU BOUAZIZ, PHILIPPE DIEUDÉ, MICKAEL GUEDJ, LARA BOSSINI-CASTILLO, SANDEEP AGARWAL, TIMOTHY RADSTAKE, et al. "Independent Replication and Metaanalysis of Association Studies Establish TNFSF4 as a Susceptibility Gene Preferentially Associated with the Subset of Anticentromere-positive Patients with Systemic Sclerosis." Journal of Rheumatology 39, no. 5 (March 15, 2012): 997–1003. http://dx.doi.org/10.3899/jrheum.111270.

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Objective.Independent replication with large cohorts and metaanalysis of genetic associations are necessary to validate genetic susceptibility factors. The known tumor necrosis factor (ligand) superfamily, member 4 gene (TNFSF4) systemic lupus erythematosus (SLE) risk locus has been found to be associated with systemic sclerosis (SSc) in 2 studies, but with discrepancies between them for genotype-phenotype correlation. Our objective was to validate TNFSF4 association with SSc and determine the subset with the higher risk.Methods.Known SLE and SSc TNFSF4 susceptibility variants (rs2205960, rs1234317, rs12039904, rs10912580, and rs844648) were genotyped in 1031 patients with SSc and 1014 controls of French white ancestry. Genotype-phenotype association analysis and metaanalysis of available data were performed, providing a population study of 4989 patients with SSc and 4661 controls, all of European white ancestry.Results.Allelic and genotypic associations were observed for the 5 single-nucleotide polymorphisms (SNP) with the subset of patients with SSc who are positive for anticentromere antibodies (ACA) and only a trend for association with SSc and limited cutaneous SSc. Rs2205960 exhibited the strongest allelic association in ACA+ patients with SSc [p = 0.0015; OR 1.37 (1.12–1.66)], with significant intra-cohort association when compared to patients with SSc positive for ACA. Metaanalysis confirmed overall association with SSc but also raised preferential association with the ACA+ subset and strongest effect with rs2205960 [T allele p = 0.00013; OR 1.33 (1.15–1.54) and TT genotype p = 0.00046; OR 2.02 (1.36–2.98)].Conclusion.We confirm TNFSF4 as an SSc susceptibility gene and rs2205960 as a putative causal variant with preferential association in the ACA+ SSc subphenotype.

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Thibord, Florian, Gaëlle Munsch, Claire Perret, Pierre Suchon, Maguelonne Roux, Manal Ibrahim-Kosta, Louisa Goumidi, Jean-François Deleuze, Pierre-Emmanuel Morange, and David-Alexandre Trégouët. "Bayesian network analysis of plasma microRNA sequencing data in patients with venous thrombosis." European Heart Journal Supplements 22, Supplement_C (April 1, 2020): C34—C45. http://dx.doi.org/10.1093/eurheartj/suaa008.

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Abstract MicroRNAs (miRNAs) are small regulatory RNAs participating to several biological processes and known to be involved in various pathologies. Measurable in body fluids, miRNAs have been proposed to serve as efficient biomarkers for diseases and/or associated traits. Here, we performed a next-generation-sequencing based profiling of plasma miRNAs in 344 patients with venous thrombosis (VT) and assessed the association of plasma miRNA levels with several haemostatic traits and the risk of VT recurrence. Among the most significant findings, we detected an association between hsa-miR-199b-3p and haematocrit levels (P = 0.0016), these two markers having both been independently reported to associate with VT risk. We also observed suggestive evidence for association of hsa-miR-370-3p (P = 0.019), hsa-miR-27b-3p (P = 0.016) and hsa-miR-222-3p (P = 0.049) with VT recurrence, the observations at the latter two miRNAs confirming the recent findings of Wang et al. Besides, by conducting Genome-Wide Association Studies on miRNA levels and meta-analyzing our results with some publicly available, we identified 21 new associations of single nucleotide polymorphisms with plasma miRNA levels at the statistical significance threshold of P < 5 × 10−8, some of these associations pertaining to thrombosis associated mechanisms. In conclusion, this study provides novel data about the impact of miRNAs’ variability in haemostasis and new arguments supporting the association of few miRNAs with the risk of recurrence in patients with venous thrombosis.

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Klionsky, Elaine J., Judy B. Okawa, Robert W. Holmstrom, David E. Silber, and Stephen A. Karp. "Word-Association Patterns of Mental Hospital Patients." Psychological Reports 83, no. 3_suppl (December 1998): 1419–24. http://dx.doi.org/10.2466/pr0.1998.83.3f.1419.

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The present study concerned an attempt to corroborate the classic findings of Rapaport, Gill, and Schafer in distinguishing mental hospital patients from control subjects, using a new objectively scored word-association test. 12 computer-scored objective scales were used to compare groups of 101 mental hospital inpatients ( n = 75, including 37 on a prison ward) and outpatients ( n = 26) and 101 control subjects matched with the patients for sex, age, racial and ethnic status, and education. A stepwise multiple discrimination analysis of the scores on the 12 scales of the test significantly distinguished the groups. Scales weighted most highly were Masochism, Antonyms, and Aggression. Subsequent t tests suggested that control subjects scored higher on Aggression, Self-reference, and Masochism scales, whereas patients scored higher on Rejections (nonresponses to stimulus words). Of these, only Self-reference and Rejections were items identified by Rapaport, et al.

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Bertrand-Hardy, Céline. "De l'écoute dans une association de patients." Contraste 24, no. 1 (2006): 167. http://dx.doi.org/10.3917/cont.024.0167.

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Niemantsverdriet, E. C., R. Breumelhof, R. Timmer, and A. J. P. M. Smout. "Symptom-reflux association in patients with GERD." Gastroenterology 114 (April 1998): A243. http://dx.doi.org/10.1016/s0016-5085(98)80988-8.

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Bodey, Gerald P. "Infection in cancer patients: A continuing association." American Journal of Medicine 81, no. 1 (July 1986): 11–26. http://dx.doi.org/10.1016/0002-9343(86)90510-3.

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Puri, Prem. "The VATER association. Analysis of 46 patients." Journal of Pediatric Surgery 21, no. 11 (November 1986): 1007. http://dx.doi.org/10.1016/s0022-3468(86)80132-4.

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Hakesley-Brown, Roswyn. "Inspection support welcomed by the patients association." Nursing Standard 26, no. 1 (September 7, 2011): 31. http://dx.doi.org/10.7748/ns.26.1.31.s42.

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KLIONSKY, ELAINE J. "WORD-ASSOCIATION PATTERNS OF MENTAL HOSPITAL PATIENTS." Psychological Reports 83, no. 7 (1998): 1419. http://dx.doi.org/10.2466/pr0.83.7.1419-1424.

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Sushma Kumari, Pant Suresh Keshav, Himanshu Chaudhary, and Ashok Kumar deo. "Association of electrocardiographic findings in COPD patients." International Journal of Science and Research Archive 8, no. 1 (January 30, 2023): 454–58. http://dx.doi.org/10.30574/ijsra.2023.8.1.0072.

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Introduction: Chronic obstructive pulmonary disease causes structural and functional changes in lung that leads to changes in cardiovascular system. This is reflected in Electrocardiogram. Material & Method: 100 COPD cases were selected from medicine OPD. GOLD staging was done by spirometry. Monthly ECG was done on every patient. Observation & results: The analysis of data was done by SPSS ver 26.0. on corelating ECG findings with GOLD staging, we found significant association for P-pulmonale and RAD however non-significant association was found for R/S in V1>1, R/S >7mm, S<2mm in V1, qR in V1 R/S in V5/V6 and other parameter of ECG. Conclusion: COPD patients shows P-Pulmonale and right ECG axis deviation in ECG.

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Filliez, Xavier. "Valais : création d’une association de patients hospitalisés." Revue Médicale Suisse 6, no. 241 (2010): 647. http://dx.doi.org/10.53738/revmed.2010.6.241.0647.

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Journal, Baghdad Science. "The Association of Myasthenia Gravis with HLA class II Antigens in Iraqi Patients." Baghdad Science Journal 10, no. 1 (March 3, 2013): 126–32. http://dx.doi.org/10.21123/bsj.10.1.126-132.

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The nature and intensity of the association of myasthenia gravis (MG) with distinct human leukocyte antigen (HLA) haplotypes differ between ethnic populations, so this study determined the association of HLA class II antigens with myasthenia gravis (MG) in Iraq.The study included Iraqi patients diagnosed with MG and two control groups the first of 54 insulin dependent diabetes mellitus patients and the second of 237 subjects as a normal control group. The test used was microlymphocytotoxicity test.The work was done in the Teaching Laboratories/Medical City/Baghdad.Results: positive associations were observed (etiological risk factors) as follows: 1. HLA-DR locus showed one positively associated allele when compared to healthy control and this was HLA-DR3 (RR: 21.05, EF0.73, & P value ? 0.05), While when compared to IDDM control no significant association appeared (since the same allele is positively associated with IDDM). 2. HLA-DQ locus showed only one positively associated allele when compared to healthy control; this was HLA-DQ2 (RR 4.67, EF 0.50, and P value ? 0.05). While no significant association appeared when compared to IDDM control. Other important clinical association were observed; association with age, gender, strong stressful events, thymoma, and other autoimmune disorders. Conclusion: The positively associated antigens which were found as follows HLA-DR3 and HLA-DQ2, while no negative association was detected.

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Shareef, Duraid Qassim Al, Rasha M. Abdulamir Al Hemiary, Khalida Mousa Al Mousawy, Hamid Fakhir Al Azawy, and Jassim Tumaa Al Khafajy. "The Association of Myasthenia Gravis with HLA class II Antigens in Iraqi Patients." Baghdad Science Journal 10, no. 1 (March 3, 2013): 126–32. http://dx.doi.org/10.21123/bsj.2013.10.1.126-132.

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The nature and intensity of the association of myasthenia gravis (MG) with distinct human leukocyte antigen (HLA) haplotypes differ between ethnic populations, so this study determined the association of HLA class II antigens with myasthenia gravis (MG) in Iraq.The study included Iraqi patients diagnosed with MG and two control groups the first of 54 insulin dependent diabetes mellitus patients and the second of 237 subjects as a normal control group. The test used was microlymphocytotoxicity test.The work was done in the Teaching Laboratories/Medical City/Baghdad.Results: positive associations were observed (etiological risk factors) as follows: 1. HLA-DR locus showed one positively associated allele when compared to healthy control and this was HLA-DR3 (RR: 21.05, EF0.73, & P value ? 0.05), While when compared to IDDM control no significant association appeared (since the same allele is positively associated with IDDM). 2. HLA-DQ locus showed only one positively associated allele when compared to healthy control; this was HLA-DQ2 (RR 4.67, EF 0.50, and P value ? 0.05). While no significant association appeared when compared to IDDM control. Other important clinical association were observed; association with age, gender, strong stressful events, thymoma, and other autoimmune disorders. Conclusion: The positively associated antigens which were found as follows HLA-DR3 and HLA-DQ2, while no negative association was detected.

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Devi, Dr Kangujam Satyabati. "Association between Diabetic Foot Ulcer and Diabetic Retinopathy." Journal of Medical Science And clinical Research 11, no. 06 (June 30, 2023): 100–105. http://dx.doi.org/10.18535/jmscr/v11i6.19.

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Diabetes mellitus is a metabolic disorder with disturbance in carbohydrate, protein and fat metabolism because of partial or complete deficiency of insulin secretion or action. As it can cause various complications and Diabetic retinopathy being the most common and perhaps the most serious of all ocular complications. Diabetic foot ulcer is one of the most serious and disabling complications of diabetes mellitus which result in significantly elevated morbidity and mortality. Aim of the study was to assess the severity of diabetic retinopathy in relation to various grades of diabetic foot ulcer among 100 patients with clinically diagnosed type 2 Diabetes Mellitus with diabetic foot ulcer patients. 25% of the study participants were found to have Moderate NPDR with 15% of the study participants having severe NPDR. 11.1% of study participants with grade 4 DFU had PDR with HRC and 33.3% of study participants with grade 4 DFU had Severe NPDR. 47.1% and 35.3% of study participants with grade 3 DFU had Severe NPDR and moderate NPDR respectively. The association was found to be statistically significant between the severity of diabetic retinopathy and the grades of diabetic foot ulcer of the study participants. The study concluded that the severity of diabetic retinopathy increases with the increase in the stages of DFU and there is a possibility that the presence of DFU can predict the progression to advanced stages of DR. The results of our study support the need for a system of ophthalmological referral in case of detection of DFU, as well as a prompt referral of DR patients to a DFU specialist. Also, in advanced age DFU patients, and particularly those with longer duration of diabetes, early detection of DR and timely treatment may decrease the risk of severe vision loss or blindness. Keywords: diabetic foot ulcer, diabetic retinopathy, risk factors, severity, India

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Hu, Jiayue, Liping Du, Wencheng Su, Shengyun Liu, Jing Deng, Qinfeng Cao, Gangxiang Yuan, Aize Kijlstra, and Peizeng Yang. "Case-Control Study and Meta-Analysis Show a Weak Association between ANTXR2 Polymorphisms and Ankylosing Spondylitis in Chinese Han." BioMed Research International 2018 (September 5, 2018): 1–7. http://dx.doi.org/10.1155/2018/8365173.

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Previous studies have demonstrated associations of ANTXR2 gene polymorphisms with ankylosing spondylitis (AS). These associations differ depending on the ethnic populations and AS subgroups studied. Purposes of the current study were to evaluate the associations of 4 single nucleotide polymorphisms (SNPs) of the ANTXR2 gene with susceptibility to AS alone or AS in combination with acute anterior uveitis (AAU) in Chinese Han. Therefore, a case-control association study was performed in 880 AS+AAU-, 860 AS+AAU+, and 1700 healthy controls. Genotyping was performed using the iPLEXGold genotyping assay. Our results showed a weak association of rs6534639 AA genotype with AS+AAU+ patients (p=0.042), which was lost after correction for multiple comparisons. No other association was found between SNPs of ANTXR2 and susceptibility of AS+AAU- or AS+AAU+. A meta-analysis was performed to evaluate the associations of polymorphisms in the ANTXR2 gene with AS. Results showed a weak association of rs4389526 with AS susceptibility in all studies but failed to show an association of rs6534639 with AS in Chinese Han. Taken together, this study shows no association between ANTXR2 polymorphisms and AS susceptibility in a Chinese Han population, but meta-analysis showed that rs4389526 in the ANTXR2 gene was weakly associated with AS susceptibility in both Caucasian and Chinese Han patients.

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Ali Beg, Mirza Masroor, Samer Riyadh Fahdil, Prasant Yadav, Kamlakant Shukla, Anant Mohan, and Alpana Saxena. "Association of EGFR 1 Gene Alteration and their Association with Lung Adenocarcinoma Patients." Asian Pacific Journal of Cancer Prevention 20, no. 3 (March 1, 2019): 825–30. http://dx.doi.org/10.31557/apjcp.2019.20.3.825.

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Gois, Gabriele Silva Souza, Silmara Aparecida Lima Montalvão, Thaizy Ramires Alencar Anhaia, Millene Evelyn Alves Almeida, Beatriz Moraes Martinelli, Maria Carmen Gonçalves Lopes Fernandes, Stephany Cares Hubers, et al. "Association of Fibrinolytic Potential and Risk of Mortality in Cancer Patients." Cancers 15, no. 17 (September 3, 2023): 4408. http://dx.doi.org/10.3390/cancers15174408.

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Cancer is a leading cause of death, and the fibrinolytic system shows cooperative effects that facilitate the growth of tumors and the appearance of metastases. This prospective study aimed to evaluate the fibrinolytic potential in cancer patients and its association with mortality outcomes using the fluorometric method of simultaneous thrombin and plasmin generation. The study included 323 cancer patients and 148 healthy individuals. During the 12-month follow-up, 68 patients died. Compared to the control group, cancer patients showed alterations in thrombin production consistent with a hypercoagulability profile, and an increase in plasmin generation. Mortality risk was associated with two parameters of thrombin in both univariate and multivariable analysis: maximum amplitude (Wald 11.78, p < 0.001) and area under the curve (Wald 8.0, p < 0.005), while such associations were not observed for plasmin. In conclusion, this was the first study able to demonstrate the simultaneous evaluation of thrombin and plasmin generation in newly diagnosed untreated cancer patients. Patients with cancer have been observed to exhibit a hypercoagulable profile. During the study, two parameters linked to thrombin generation, MA and AUC, were identified and found to have a potential association with mortality risk. However, no associations were found with parameters related to plasmin generation.

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Kumar, Kuldeep. "Iron Homeostasis in Patients with Nonalcoholic Fatty Liver Disease." Journal of Advanced Research in Medicine 08, no. 02 (June 30, 2021): 6–10. http://dx.doi.org/10.24321/2349.7181.202107.

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Introduction: Serum ferritin correlates with hepatic iron deposition in patients with Non Alcoholic Fatty Liver Disease (NAFLD). Iron removal improves insulin sensitivity thereby delaying the onset of type 2 diabetes mellitus, improves liver function and NAFLD histology. Objectives: This study was done to assess the iron status in NAFLD patients and its association with fibrosis and metabolic syndrome in NAFLD. Material and Method: The study was conducted in the Department of Medicine, GTB Hospital, Delhi from November 2017 - October 2019. It was an Analytical, comparative study. Forty patients with NAFLD were selected in the study group and forty healthy subjects with no evidence of fatty liver on ultrasound were selected in the control group. The level of iron parameters recorded in NAFLD patients and the control group were compared using independent t test and p value of <0.05 was considered statistically significant. Assessment of association of various parameters of iron status with the presence of Metabolic Syndrome and fibrosis in NAFLD patients was done using the Chi-Square test. Result: The parameters of iron status namely serum iron, serum ferritin, transferrin saturation and serum hepcidin were found to be higher in NAFLD patients when compared to controls. This study also observed that there was a statistically significant positive association of serum ferritin with the presence of MetS in NAFLD patients. The study also found that serum hepcidin and serum ferritin have a significant positive association with fibrosis in NAFLD. Discussion: Assessment of iron status in NAFLD may help in early identification of individuals at high risk of fibrosis and other complications like Mets. Application of iron removal strategies like phlebotomy in such patients might improve IR and NAFLD.

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Mayer, Christopher C., Christoph Schmaderer, Charalampos Loutradis, Julia Matschkal, Marrieta Theodorakopoulou, Georg Lorenz, Antonios Karpetas, et al. "Heart Failure and Atrial Fibrillation Modify the Associations of Nocturnal Blood Pressure Dipping Pattern With Mortality in Hemodialysis Patients." Hypertension 76, no. 4 (October 2020): 1231–39. http://dx.doi.org/10.1161/hypertensionaha.120.15420.

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Heart failure (HF), hypertension, and abnormal nocturnal blood pressure dipping are highly prevalent in hemodialysis patients. Atrial fibrillation (AF) and HF might be important mediators for the association of abnormal dipping patterns with worse prognosis. Thus, the aim of this study is to investigate the association of dipping with mortality in hemodialysis patients and to assess the influence of AF and HF. In total, 525 hemodialysis patients underwent 24-hour ambulatory blood pressure monitoring. All-cause and cardiovascular mortality served as end points. Patients were categorized according to their systolic dipping pattern (dipper, nondipper, and reverse dipper). Cox regression analysis was performed to determine the association between dipping pattern and study end points with dipping as reference. Subgroup analysis was performed for patients with and without AF or HF. In total, 185 patients with AF or HF and 340 patients without AF or HF were included. During a median follow-up of 37.8 months, 177 patients died; 81 from cardiovascular causes. Nondipping and reverse dipping were significantly associated with all-cause mortality in the whole cohort (nondipper: hazard ratio, 1.95 [1.22–3.14]; P =0.006; reverse dipper: hazard ratio, 2.31 [1.42–3.76]; P <0.001) and in patients without AF or HF (nondipper: hazard ratio, 2.78 [1.16–6.66]; P =0.02; reverse dipper: hazard ratio, 4.48 [1.87–10.71]; P <0.001) but not in patients with AF or HF. For cardiovascular mortality, associations were again significant in patients without AF or HF and in the whole cohort. The observed associations remained significant after adjustment for possible confounders. This study provides well-powered evidence for the association between abnormal dipping patterns and mortality in hemodialysis patients and suggests that HF or AF modifies this association.

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Solano, P., M. Ustulin, R. Vecchio, A. Rreshketa, E. Pizzorno, G. Serafini, and M. Amore. "Suicidal ideation and organic diseases in acute female psychiatric patients." European Psychiatry 33, S1 (March 2016): s275. http://dx.doi.org/10.1016/j.eurpsy.2016.01.732.

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IntroductionPhysical illness has been recognized as a major risk factor for suicidal behaviours, especially among females. A higher number of physical comorbidities has been associated with higher suicide- risk, thus having a greater burden among the elderly.Objectivesinvestigate this evidence to be able to estimate the load of physical illness on suicidality among psychiatric females of different age.AimsEvaluate the association between suicidal ideation, age, depression and physical comorbidities in a sample of acute females psychiatric in-patients.Methods81 psychiatric female in-patients were evaluated during their first day of hospitalization through MADRS, SSI and the presence of organic comorbidity has been collected together with demographic data. All the evaluations were carried out at the Psychiatric Clinic, University of Genova, Italy.ResultsMean age 48 (age–range value: 74, high variability). Pearson's Chi-squared test showed: significant association between SSI and MADRS (P = 0,027; α = 0,05); no association between SSI and age (P = 0,194; α=0,05); no association between SSI and presence medical illness (P = 0,132; α = 0,05); no association between SSI and number of medical illness (P = 0,186; α = 0,05).ConclusionsOur results show that the levels of suicidal ideation in psychiatric females are independent from age, presence and number of physical comorbidities. Suicidal ideation appears to be associated only with levels of depression. Our results challenge evidence from a large number of current studies and, if confirmed by further research, would lead to reconsider major suicide risk factors. Further research to investigate these associations on larger samples is needed.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Gray, Natalie N., Lindsay R. Villalobos, Milre Matherne, Aric Schadler, and Tyler E. Bosley. "Association of Chemotherapy Regimen Intensity and Use of Psychotropic Medications in Pediatric Oncology Patients." Journal of Pediatric Pharmacology and Therapeutics 27, no. 7 (September 1, 2022): 649–54. http://dx.doi.org/10.5863/1551-6776-27.7.649.

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OBJECTIVE Pediatric oncology patients endure treatments that may include chemotherapy, surgery, radiation, and transplant. These treatment modalities often have an effect on a patient's mental health. To date, little is known or published about the association between certain cancer treatment regimens and the use of psychotropic medications. The goal of this study is to identify associations between the use of psychotropic medications in pediatric oncology patients in relation to the intensity of their oncologic treatment regimen. METHODS A retrospective chart review was completed for pediatric oncology patients seen between the years of 2009 and 2019 with prescriptions and/or inpatient orders for specific psychotropic medications. The intensity of the oncologic regimen was categorized using the Intensity of Treatment Rating Scale (ITR-3) tool. Association between the intensity of therapy and use of psychotropic medications were compared using Pearson χ2 and Fisher exact tests as appropriate. RESULTS There were 172 patients identified as having inpatient and/or outpatient orders for psychotropic medications during the study period. Ninety-one pediatric oncology patients were included in data analysis. It was found that psychotropic medications were used consistently in pediatric oncology patients despite a specific ITR-3 score. There were no statistically significant associations found when comparing ITR-3 scores to psychotropic medication use or to age at diagnosis. CONCLUSIONS Significance was not obtained in this study; however, we found that psychotropic medications were used across the spectrum of diagnoses, age, and oncologic treatment intensity. This suggests that all pediatric oncology patients should be evaluated for psychiatric needs throughout their course of oncologic treatment.

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Poljacki, Mirjana, Mirjana Begenesic, Verica Djuran, Ljubinka Matovic, Milan Matic, Marina Jovanovic, Slobodan Stojanovic, and Tatjana Ros. "Psoriasis and autoimmune skin diseases." Medical review 55, no. 7-8 (2002): 325–28. http://dx.doi.org/10.2298/mpns0208325p.

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Introduction Presuming that psoriasis is an autoimmune skin disease, the aim of this study was to establish its association with other autoimmune skin diseases. The material was obtained at the Dermatovenereological Clinic Clinical Center Novi Sad. Material and methods This 10-year retrospective study (1990-1999) included 1743 psoriasis patients. The control group consisted of 7492 nonpsoriatic dermatological patients. Results Association of psoriasis with other dermatological diseases of autoimmune nature has been established in 13 (0.74 %) patients. The most frequent association was with lichen ruber planus in five patients, with alopecia areata and vitiligo in three patients, and in one with bullous pemphigoid and herpetiform dermatitis. Using Fisher's test no significant association was established. Discussion and conclusion According to literature data association of psoriasis with other autoimmune diseases is well known, but rare, which is in accordance with our results. The question arises whether this association is the matter of poor coexistence or the matter of genetic mutations. However, once established, these associations can further highlight the autoimmune nature of psoriasis. The research of autoimmunity would lead us to epithelial cells in thymus, and their badly learnt cognitive function about what is own, and what is not.

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Gupta, Pooja. "Study of Association of Lipoprotein (A) Levels with Carotid Atherosclerosis in Young Patients with Ischemic Stroke." International Journal of Neurology and Neurosurgery 10, no. 4 (2018): 133–38. http://dx.doi.org/10.21088/ijnns.0975.0223.10418.7.

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Andure, Dr Dhananjay V., Dr Mrs Anita M Raut, Dr R. K. Padalkar, and Miss Patil S. M. "To Correlate the Association of Markers of Chronic Renal Failure in Patients With and without Haemodialysis." Scholars Journal of Applied Medical Sciences 4, no. 7 (July 2016): 2312–17. http://dx.doi.org/10.21276/sjams.2016.4.7.1.

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