Дисертації з теми "Association de patients"
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1
Jenkins, Valerie Ann. "Novel word association priming in amnesic patients." Thesis, University of Sussex, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307247.
2
Oi, Katsuya. "Understanding the Role of Patient Activation in the Association between Patient Socio-Economic Demographics and Patient Experience." PDXScholar, 2012. https://pdxscholar.library.pdx.edu/open_access_etds/467.
Анотація:
This study focuses on the association between patient characteristics, which include both demographic and contextual factors, and patients' experiences with health care. The pre-existing literature provides rich information about patients' various demographics related to patient experience. Despite the abundance of empirical evidence showing that patients' demographics do affect how they perceive their health care. However, there is little to no empirical knowledge explaining the significance of such factors. As the existing literature points out the need for taking into contextual factors such as patient's beliefs, attitudes, skills that are pertinent to dealing with health care, my study proposes patient activation as such a contextual factor that explains the association between patient demographics and patient experience. Findings suggest that patient activation is a strong predictor of two patient experience measures: patients' rating of doctor-patient communication and their self-reported difficulties in getting needed care. However, it is also observed that the mediating effects of patient activation vary by the two dimensions of patient experiences. Though this study demonstrates that promoting patient activation may be able to normalize how patients report the quality of doctor-patient interaction, further research is needed to address access to care issues.
3
Wood, Lucille. "The association of anaemia and plasmapheresis in hypercholesterolaemic patients." Master's thesis, University of Cape Town, 1994. http://hdl.handle.net/11427/24967.
4
Schirg, Glenn Richard. "Determining the patient satisfaction factors for hospital room service & the association of room service with the overall satisfaction with the hospital experience." Menomonie, WI : University of Wisconsin--Stout, 2007. http://www.uwstout.edu/lib/thesis/2007/2007schirgg.pdf.
5
Kuhn, Tyler A. "The Association between Health Literacy and Mortality in Heart Failure Patients." Kent State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=kent157123026478637.
6
Coley, Rose Michelle. "The Association of Cancer Development in Patients with Systemic Lupus Erythematosus." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2148.
Анотація:
The Association of Cancer Development in Patients with Systemic Lupus Erythematosus by
Rose Michelle Coley
MPH, Walden University, 2011
BS, University of Mount Olive, 2008
Dissertation Submitted in Partial Fulfillment
of the Requirements for the Degree of
Doctor of Philosophy
Public Health
Walden University
March 2016
Both cancer and autoimmune diseases have been associated with numerous factors that may independently lead to the development of either disease. When these factors overlap the difficulty in assessing association is compounded. The numerous factors that are thought to cause systemic lupus erythematosus (SLE), which leads to the development of cancer, makes the study of an association between the 2 diseases challenging. The purpose of this study was to examine whether the risk of cancer development increased in SLE patients compared to the risk in non-SLE patients. Researchers have not shown consistent relationships of cancer development in patients with SLE; however, consideration of the various factors that contribute to the diseases is necessary to measure an association between the 2 diseases. This study used the Clinical Practice Research database (CPRD), a large, population-based database to test the relationship between SLE and cancer. A matched retrospective cohort study among SLE (n=3025) and non-SLE (n=180555) patients was conducted using the propensity score methodology to help balance the differences between the comparison groups. The propensity score methodology created a similar distribution of observed baseline covariates between the 2 groups. With adjustment for age, the predictor variable of SLE indicates that a patient with SLE is still 2.7 times more likely to develop cancer than is a non-SLE patient. The study outcomes could promote positive social change by reinforcing current recommendations for cancer screenings in persons with SLE, which could enhance the ability to detect cancer early enough to decrease mortality because of cancer in persons with SLE.
7
Valiquette, Luc François. "Association between self-reported childhood maltreatment and cortisol profiles in psychotic patients." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112314.
Анотація:
Childhood maltreatment is extremely common in patients diagnosed with psychotic disorders. Moreover, it has been linked with impaired functioning of the Hypothalamic-Pituitary-Adrenal axis. Furthermore, abnormality of the HPA has been found in psychotic patients. Presence of childhood maltreatment could then explain why the HPA axis is dysfunctional in these subjects. Our objective was to clarify the role of childhood trauma in the cortisol profiles of psychotic patients. Thirty-one patients underwent assessments of childhood maltreatment. Diurnal cortisol and cortisol after a controlled psychosocial stress were also collected. Our results show that childhood trauma is associated with lower cortisol levels during the morning and during 24 hours. In men diagnosed with psychosis, childhood trauma is also associated with a higher cortisol response during psychosocial stress. This suggests an alteration of the HPA axis in psychotic patients, resulting from early trauma. Moreover, our results suggest that looking at specific types of childhood abuse may also be important.
8
Stroputė, Dalia. "Association between weather and well-being of patients with coronary artery disease." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140711_091353-69865.
Анотація:
Research shows that the interaction between the weather conditions and human health exists and this interaction has a very wide range, from subjective well-being to death. With respect to reactions to weather variations, people can be divided into weather-resistant and weather-sensitive. However, there is the lack of standardised tools to evaluate weather sensitivity. People with heart disease and people with sensitive nervous system are considered to be more sensitive to weather change than others. There are evidences that psychological distress and Type D personality are both associated with development and progression of coronary artery disease. Also, it is hypothesized that individual differences such as personality traits may have an effect on sensitivity to weather. The aim of this study was to examine and to evaluate associations between weather parameters and subjective well-being of patients with coronary artery disease. The objectives of the study: 1) to examine the validity of Type D personality assessment instrument used in this study; 2) to develop and test the psychometric properties of self-assessment diary for weather sensitivity in patients with coronary artery disease; 3) to evaluate associations between the subjective well-being of patients with coronary artery disease and the weather parameters; 4) to evaluate associations between anxiety, depression and personality and the subjective weather-related well-being in patients with coronary artery disease.Moksliniai tyrimai rodo, kad egzistuoja sąveika tarp orų pokyčių ir žmonių sveikatos ir ši sąveika sudaro labai platų spektrą – nuo subjektyvios savijautos pablogėjimo iki mirties. Dėl reakcijų į orų pokyčius, žmonės gali būti suskirstyti į dvi grupes – jautrius orų pokyčiams ir atsparius. Tačiau standartizuotų instrumentų, kurie leistų įvertinti jautrumą orams ir atskirti jautrius orų pokyčiams asmenis, ypač skirtingų susirgimų grupėse, trūksta. Sergantieji širdies ligomis ir asmenys išgyvenantys psichologinį distresą priskiriami prie vienų iš jautriausių orų pokyčiams. Įrodyta, kad tiek psichologinis distresas, tiek asmenybės D tipas yra susiję su išeminės širdies ligos išsivystymu ir progresavimu. Be to, pastaraisiais metais keliamos hipotezės, kad individualūs skirtumai, tokie kaip asmenybės bruožai, taip pat gali įtakoti jautrumą orams. Darbo tikslas buvo išnagrinėti ir įvertinti sergančiųjų išemine širdies liga subjektyvios savijautos sąsajas su orais ir jos ryšį su asmenybės bruožais, nerimo ir depresijos simptomais. Darbo uždaviniai: 1) validizuoti tyrime naudojamą instrumentą asmenybės D tipui vertinti; 2) sukurti savikontrolės dienyną jautrumui orams įvertinti ir atlikti jo psichometrinę analizę; 3) nustatyti sąsajas tarp sergančiųjų išemine širdies liga subjektyvios savijautos ir orų, 4) įvertinti sergančiųjų išemine širdies liga subjektyvios orų sąlygotos savijautos sąsajas su nerimu, depresija ir asmenybės bruožais.
9
El-Genidy, Noha A. F. "Association of PTCH polymorphism with clinical phenotype in basal cell carcinoma patients." Thesis, Keele University, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436141.
10
Navarro, Trujillo Rodrigo. "Association of inflammation markers in young adult patients with Obsessive-compulsive disorder." Thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-355094.
Анотація:
Background: Previous studies have shown that patients with obsessive-compulsive disorder (OCD) have elevated interleukin and chemokine levels in plasma. The purpose of this study was to investigate and validate whether a group of cytokines and chemokines are elevated in a cohort of young adult OCD patients. Methods: A total of 43 patients (11 male/32 female) and 45 controls (15 male/30 female) with OCD were included in the study. The subjects were assessed with the Structured Clinical Interview for DSM-IV Axis I Disorders- Clinical Version or Mini-International Neuropsychiatric Interview. The control group was screened with the Alcohol Use Disorders Identification Test. Proximity extension assay (PEA) was used to measure plasma levels of IL-6, IL-8, MIP-1α, and IL-10. Results: A factor analysis for the cytokines was performed and logistic regression analysis revealed that the cytokines as a group have a significant association for OCD (P=0.031, OR: 2.2) and IL-8 was the cytokine with the highest significance (P=0.007) for the patient group. Conclusion: These findings suggest that this group of cytokines are associated with OCD diagnosis and strengthens previous findings of immune activity in the etiology of OCD. Therefore cytokines and chemokines could have an active role in the etiology of OCD and PEA could be useful in the search for biomarkers.
11
MAHE, BEATRICE. "Association de proliferations myeloide et lymphoide b chez 6 patients : origine commune ?" Nantes, 1991. http://www.theses.fr/1991NANT090M.
12
Fujii, Kota. "Association of Chemoradiotherapy With Thoracic Vertebral Fractures in Patients With Esophageal Cancer." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/264656.
13
Savall, Angélique. "Sociologie d'une cohorte : Naissance et maintenance d’un outil scientifique devenu forme de vie associative." Electronic Thesis or Diss., Lyon, 2021. http://www.theses.fr/2021LYSES019.
Анотація:
En 2001, Marguerite intègre le projet de cohorte Proof et accepte de devenir « sujet » d’une recherche médicale. Comme elle, 1011 séniors stéphanois s’engagent dans l’aventure. Les scientifiques ambitionnent de déterminer la valeur pronostique de la perte d’activité du Système Nerveux Autonome (SNA) sur la mortalité. En 2004, le financement de la recherche devient complexe. Michel, sujet de l’étude, propose un don financier. Les chercheurs l’incitent à créer une association pour tenter de venir en aide à l’équipe : l’association Synapse vient de naître pour sauver l’étude Proof. Cette enquête sociologique propose de réinterroger cette forme sociale qu’est la cohorte, outil humain de la recherche en santé. Ce travail envisage, dans un premier temps, la cohorte comme outil de laboratoire aux mains des scientifiques. L’étude de cohorte va se révéler être un outil opportun pour venir instrumentaliser la mesure de l’activité du SNA puis équiper les relations entre les chercheurs et les sujets. Dans la seconde partie, la cohorte aura basculé aux mains des sujets devenus adhérents. L’association s’inscrit dans une logique du care face à un outil cohorte fragile. Écoute sociale, travail de maintenance technique, moral et relationnel seront alors indispensables. Ce travail a pour ambition d’analyser une transformation ontologique d’une forme – la cohorte – initialement instrument de laboratoire puis groupe d’individus qui s’engage volontairement au service de la recherche. Elle tend à montrer à travers cette transition la spécificité de la cohorte comme objet frontière entre chercheurs experts et sujets profanes, entre recherche médicale scientifique et gens ordinairesIn 2001, Marguerite joined the Proof cohort project and agreed to become a "subject" of medical research. Like her, 1011 seniors from Saint-Etienne joined the adventure. The scientists aim to determine the prognostic value of the loss of activity of the Autonomic Nervous System (ANS) on mortality. In 2004, the financing of the research became complex. Michel, a subject of the study, proposed a financial donation. The researchers encouraged him to create an association to try to help the team: the Synapse association was created to save the Proof study. This sociological investigation proposes to reexamine the social form of the cohort, a human tool for health research. This work first considers the cohort as a laboratory tool in the hands of scientists. The cohort study will prove to be an opportune tool to instrumentalize the measurement of the activity of the ANS and then to equip the relations between researchers and subjects. In the second part, the cohort will be in the hands of the subjects who have become members. The association is part of a logic of care for a fragile cohort tool. Social listening, technical, moral and relational maintenance work will then be indispensable. This work aims at analyzing an ontological transformation of a form - the cohort - initially a laboratory instrument and then a group of individuals who voluntarily commit themselves to the service of research. It tends to show through this transition the specificity of the cohort as a frontier object between expert researchers and lay subjects, between scientific medical research and ordinary people
14
Tsai, Huei-Ting North Kari E. "Association between tardive dyskinesia and dopamine receptor genes among patients with chronic schizophrenia." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1394.
Анотація:
Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.Title from electronic title page (viewed Apr. 25, 2008). " ... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Epidemiology, School of Public Health." Discipline: Epidemiology; Department/School: Public Health.
15
Alshorman, H. M. "The association between periodontal disease and Type 2 diabetes mellitus in Jordanian patients." Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.479254.
16
Castro, Juliana Ramiro Luna. "Quality of life in patients with neoplasms hemodialysis : association with complex malnutrition - inflammation." Universidade Federal do CearÃ, 2014. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=12918.
Анотація:
FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgicoIntroduction: The aim of this study was to compare levels of depression, quality of life and sleep quality between hemodialysis patients with or without cancer and to analyze associations with malnutrition-inflammation-atherosclerosis (MIA) syndrome. Methods: In this cross-sectional study 40 cancer patients under hemodialysis and 44 patients under hemodialysis without cancer who served as the control group were included. Participants underwent structured interviews to investigate depression, quality of life, sleep quality and restless legs syndrome. Results: Hemodialysis patients with cancer had a greater depression score (16.54.8 vs. 10.85.2, p<0.001), and Patients had similar physical and mental composite quality of life scores. Patients under hemodialysis with cancer had poorer quality of sleep (mean score 8.83.5 vs. 6.44.1, p=0.011) and a higher prevalence of restless leg syndrome (55.9% vs. 25.7%, p=0.011). Hemodialysis patients with cancer had a mean MIA Syndrome greater than those without cancer (15.15.7 vs. 10.04.7, p<0.001). Conclusion: Cancer patients under hemodialysis present a higher prevalence of depression, poor quality of life, poor quality of sleep disorders and increased frequency of malnutrition-inflammation syndrome compared to their non-cancer counterparts.
IntroduÃÃo: O objetivo deste estudo foi comparar os nÃveis de depressÃo, qualidade de vida e qualidade de sono entre pacientes em hemodiÃlise, com ou sem neoplasia e analisar a associaÃÃo com desnutriÃÃo-inflamaÃÃo-aterosclerose (MIA) sÃndrome. MÃtodos: Neste estudo transversal, foram incluÃdos 40 pacientes com neoplasia em hemodiÃlise e 44 pacientes em hemodiÃlise sem neoplasia como grupo de controle. Os participantes foram submetidos a entrevistas estruturadas para investigar depressÃo, qualidade de vida, qualidade do sono e sÃndrome das pernas inquietas. Os dados foram tabulados e analisados atravÃs de software estatÃstico Microsoft Excel 2007 e Statistical Package for Social Sciences (SPSS) Resultados: pacientes em hemodiÃlise com neoplasia tiveram maior escore de depressÃo (16,5 4,8 vs 10,8 5,2, p <0,001) , e os pacientes tiveram semelhante escores de qualidade de vida composto fÃsica e mental quando comparado ao grupo controle. Os pacientes em hemodiÃlise com neoplasia tinham pior qualidade de sono (pontuaÃÃo mÃdia de 8,8 3,5 vs 6,4 4,1, p = 0,011) e maior prevalÃncia de sÃndrome das pernas inquietas (55,9% vs 25,7%, p = 0,011) quando comparado aos pacientes em hemodiÃlise sem neoplasia. Pacientes em hemodiÃlise com neoplasia tiveram MIA syndrome maior do que aqueles sem neoplasia (15,15,7 vs 10,0 4,7, p < 0,001). ConclusÃo: Os pacientes com neoplasia em hemodiÃlise apresentam uma maior prevalÃncia de depressÃo, mà qualidade de vida, a mà qualidade dos distÃrbios do sono e aumento da frequÃncia de sÃndrome de desnutriÃÃo-inflamaÃÃo em comparaÃÃo com suas contrapartes nÃo-cancerosas. .
17
Chakraborty, A. T. "Association between perceived racism and medication adherence in patients of Caribbean origin with psychosis." Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/1444140/.
Анотація:
Research shows that UK Caribbean patients with psychosis have more aversive pathways in psychiatric care compared with the white British population. This may indicate "cultural mistrust" of services which is attributed by Caribbean patients to racism, explaining their poorer adherence and engagement with services. Mistrust may reflect a mismatch in the attribution of illness between patient and psychiatrist: whereby the patient perceives both his predicament and services as racist and oppressive, whilst the psychiatrist over-estimates the "dangerousness" of the patient. No study to-date has examined the association between the perception that society and services are racist and adherence with psychiatric treatment in Caribbean patients with psychosis. This is a London-based prospective cohort study of 100 Caribbean patients with psychosis. It uses the Perceived Racism Scale (PRS - a multi-dimensional measure of self-reported racism), the Drug Attitudes Inventory (DAI) and the Kemp seven-point scale (a commonly used self-report and multi-sourced measure of adherence, respectively). Perceived racism was measured at baseline using the PRS, with adherence and hospital admission data determined after 12 months, using the DAI and Kemp Scale. The study found small but independent and significant associations between measures of total perceived racism for the previous year, over a lifetime, and everyday racism for the previous year, with medication adherence one year later. It also found that feeling ashamed and powerless about any racism that was personally experienced within the health system were associated with increased adherence and fewer hospital bed-days in the subsequent year. Finally, the strongest positive association was between perceived racism within the system and both the number of subsequent hospital bed-days and length of hospital admission over the next year. This implies that in this group of UK Caribbean patients with psychosis, perceived racism is a determinant of adherence with psychotropic medication over a twelve-month period.
18
Pinto, Ana Catarina Moreira. "Association between anthropometric indicators of nutritional status and length of stay in hospitalized patients." Bachelor's thesis, [s.n.], 2018. http://hdl.handle.net/10284/7361.
Анотація:
Trabalho Complementar apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de licenciada em Ciências da NutriçãoBackground: Undernutrition is highly prevalent in hospitalized patients worldwide and this condition has been associated with increased hospital length of stay (LOS). The diagnosis of undernutrition includes anthropometric measurements. The aim of this study was to measure the independent association of the anthropometric and derived indicators triceps skinfold thickness (TST), mid-upper arm circumference (MUAC), adductor pollicis muscle thickness (APMT), mid-upper arm muscle area (AMA) and mid-upper arm muscle circumference (AMC) with LOS, within a varied group of hospitalized patients. Methods: A total of 695 patients were enrolled in a prospective observational study, conducted in a Portuguese university hospital. Participants were dichotomized for the anthropometric and derived indicators TST, MUAC, APMT, AMA and AMC according to the percentiles 5th and 25th described in the literature, except for APMT, for which only the 5th percentile was used. Cox regression analysis was used to estimate adjusted hazard ratios (HR) and corresponding 95% confidence intervals (95% CI). Results: Patients that presented values lower than the 5th percentile for TST (HR=0.759, 95% CI=0.579;0.995), MUAC (HR=0.822, 95% CI=0.687;0.983), APMT (HR=0.791, 95% CI=0.671;0.933), AMA (HR=0.797, 95% CI=0.660;0.962) and AMC (HR=0.746, 95% CI=0.611;0.911), showed a lower probability of being discharged from the hospital to usual residence over time. For TST (HR 0.798, 95% CI=0.673;0.946), patients whose values were below the 25th percentile also presented a lower probability of being discharged from the hospital to usual residence over time. Conclusion: For all the anthropometric and derived indicators studied, patients that presented values lower than the 5th percentile had a lower probability of being discharged from the hospital to usual residence. For TST, values below the 25th percentile were also associated with lower probability of discharge. Thus, TST was found to be the best anthropometric indicator to predict LOS. This anthropometric indicator can present advantages for the diagnosis of undernutrition since it may allow an earlier detection of a poor nutritional status.
Introdução: A desnutrição apresenta elevada prevalência em doentes hospitalizados e esta condição tem vindo a ser associada com maior tempo de internamento (TI). O diagnóstico da desnutrição inclui indicadores antropométricos. O objetivo deste trabalho foi estudar a associação independente entre os indicadores antropométricos prega cutânea tricipital (PCT), perímetro do meio braço (PB), espessura do músculo adutor do polegar (AP), área muscular do braço (AMB) e perímetro muscular do braço (PMB) e o TI em doentes hospitalizados. Métodos: 695 indivíduos participaram num estudo observacional realizado num hospital universitário Português. Os participantes foram dicotomizados para cada indicador antropométrico PCT, PB, AP, AMB e PMB de acordo com os percentis 5 e 25 descritos na literatura, exceto para o AP, para o qual apenas o percentil 5 foi utilizado. Utilizaram--se modelos de regressão de Cox para calcular os hazard ratios (HR) e os intervalos de confiança a 95% (IC 95%) correspondentes. Resultados: Os participantes que apresentaram valores abaixo do percentil 5 para PCT (HR=0,759; IC 95%=0,579;0,995), PB (HR=0,822; IC 95%=0,687;0,983), AP (HR=0,791; IC 95%=0,671;0,933), AMB (HR=0,797; IC 95%=0,660;0,962) e PMB (HR=0,746; IC 95%=0,611;0,911), revelaram uma menor probabilidade de alta para o domicílio. Para a PCT (HR=0,798; IC 95%=0,673;0,946), apresentar valores abaixo do percentil 25 também se associou a uma menor probabilidade de alta para o domicílio. Conclusão: Os participantes que apresentaram valores abaixo do percentil 5 para todos os indicadores antropométricos mostraram uma menor probabilidade de alta domiciliar. Para a PCT, o percentil 25 também foi associado com uma menor probabilidade de alta para o domicílio. A PCT foi então o melhor indicador antropométrico capaz de prever o TI hospitalar. Incluir este indicador antropométrico nos métodos de diagnóstico de desnutrição pode ser uma mais valia por poder detetar mais precocemente um pior estado nutricional.
N/A
19
Качковська, Владислава Володимирівна, Владислава Владимировна Качковская, Vladyslava Volodymyrivna Kachkovska, Анна Володимирівна Ковчун, Анна Владимировна Ковчун, Anna Volodymyrivna Kovchun, Олександр Вікторович Орловський, et al. "Association between capillaroscopic alterations and angiogenic and tissue remodeling factors in patients with dermatomyositis." Thesis, BMJ, 2020. https://essuir.sumdu.edu.ua/handle/123456789/87105.
Анотація:
During last years we are seeking for new biomarkers of early or even preclinical diseases stages, precise definition of disease activity and accurate prediction of the disease course as well as biomarkers of treatment efficiency. Nailfold capillaroscopy (NFC) considering as a method for early or even preclinical diagnostic tool for systemic scleroderma, at the same time there is enough data that dermatomyositis (DM) characterized with similar NFC changes along with other idiopathic inflammatory myopathies (IIM) due to the peripheral vascular involvement.
20
Мудренко, Ірина Григорівна, Ирина Григорьевна Мудренко, Iryna Hryhorivna Mudrenko, Ольга Сергіївна Чиняк, Ольга Сергеевна Чиняк, and Olha Serhiivna Chyniak. "Association between IL-17, IL-23 with neurocognitive scales in patients with Alzheimer’s disease." Thesis, Cambridge University Press, 2021. https://essuir.sumdu.edu.ua/handle/123456789/87570.
Анотація:
Alzheimer’s disease (AD) is a degenerative brain disease and the most common cause of dementia. Evidence suggests that various cytokines, including interleukins (IL) IL-6, IL-10, IL-12 are actively involved in the pathogenesis of AD. The role of IL-17 and IL-23 is less clear.
21
Crispín, Trebejo Brenda, Cuadros María Cristina Robles, and Antonio Bernabe-Ortiz. "Association between depression and glycemic control among type 2 diabetes patients in Lima, Peru." Wiley Publishing Asia Pty Ltd, 2015. http://hdl.handle.net/10757/556689.
Анотація:
maria.cristina.rc2690@gmail.comArticle
Introduction: There is limited and controversial information regarding the potential impact of depression on glycemic control. This study aims to evaluate the association between depression and poor glycemic control. In addition, the prevalence of depression and rates of poor glycemic control were determined. Methods: Cross-sectional study performed in the endocrinology unit of two hospitals of ESSALUD in Peru. The outcome of interest was poor glycemic control, evaluated by glycated hemoglobin (HbA1c: < 7% versus ≥ 7%), whereas the exposure of interest was depression defined as 15 or more points in the Patient Health Questionnaire-9 tool. The association of interest was evaluated using Poisson regression models with robust standard errors reporting prevalence ratios (PR) and 95% confidence intervals (95% CI) adjusting for potential confounders. Results: A total of 277 participants, 184 (66.4%) males, mean age 59.0 (SD: 4.8), and 7.1 (SD: 6.8) years of disease were analyzed. Only 31 participants (11.2%; 95% CI: 7.5%–14.9%) had moderately severe or severe depression, whereas 70 (25.3%; 95% CI 20.3%–30.8%) had good glycemic control. Depression increased the probability of having poor glycemic control (PR = 1.32; 95% CI 1.15–1.51) after adjusting for several potential confounders. Conclusions: There is an association between depression and poor glycemic control among type 2 diabetes patients. Our results suggest that early detection of depression might be important to facilitate appropriate glycemic control and avoid further metabolic complications.
We would like to thank Dr Viviana Ulloa who helped us to access data and T2D patients, and Dr Percy Mayta- Tristan for revising initial versions of the manuscript. AB-O is supported by Wellcome Trust Research Training Fellowship in Public Health and Tropical Medicine (Grant number 103994/Z/14/Z).
Revisión por pares
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Emery, Alfred Wyatt. "The association between adult literacy and patient education factors of non-insulin dependent diabetic patients at risk for lower extremity amputation /." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487687115925421.
23
Barth, Nathalie. "L'activité physique adaptée pour les personnes atteintes de diabète de type 2 : approche sociologique des "carrières de pratiquant d'APA" dans leurs relations avec la "trajectoire de maladie"." Phd thesis, Université Claude Bernard - Lyon I, 2012. http://tel.archives-ouvertes.fr/tel-00862795.
Анотація:
Outre la prescription d'un traitement médicamenteux, la pratique régulière d'une Activité Physique Adaptée (APA)est recommandée aux personnes atteintes d'un diabète de type 2 (DT2), au même titre qu'un nouvel équilibre alimentaire(HAS, 2006). Cette incitation à opérer des changements concrets dans son " style de vie " rencontre des résistances, qui sontaccentuées pour les malades n'ayant pas préalablement construit de dispositions à la pratique physique. Des dispositifsinnovants ont été imaginés dans certaines organisations de santé (réseau de santé, unité transversale d'éducation) pour rendrepossible cet engagement physique et lui permettre de se développer de manière autonome dans le cadre d'" une carrière depratiquant d'APA " au sens où la définit Becker (1985). L'objectif est d'étudier ce processus d'engagement dans ses relationsavec la " trajectoire de maladie " au sens où l'entend Strauss (1985), en rendant compte des différentes étapes de saconstruction. A l'interface de la sociologie de la santé et de la sociologie du sport, l'approche mobilise ainsi des conceptsinteractionnistes. La méthodologie articule une observation de terrain avec 52 récits d'expériences de personnes atteintes demaladie(s) chronique(s) (dont 39 de DT2) qui ont évolué dans deux dispositifs d'APA différents : l'un proposant des séancesthéoriques d'information/explication (n=17), l'autre mettant en place des séances pratiques dans un cycle éducatif en APA puisune orientation vers une association sportive de patients (n=35). L'analyse des récits utilise un logiciel de traitement dedonnées textuelles (Prospéro).Trois types d'engagement ont ainsi été repérés : Le premier s'inscrit dans la " trajectoire demaladie " mais suppose un rapport au corps renouvelé après une remise en question des représentations de l'AP du patient etde ses capacités. Le second ouvre une " carrière de pratiquant d'APA " et ajoute une sociabilité de l'entre-soi, initiée par lesdispositifs " à et via " l'APA. Le troisième consolide cette " carrière " dans une pratique davantage culturelle que médicale,en l'inscrivant dans une sociabilité plus ouverte. Ces trois formes d'engagement se succèdent selon un continuum au coursduquel s'affirment simultanément une recherche croissante d'autonomie par rapport aux prescriptions médicales, une attentiongrandissante au corps et un développement du réseau relationnel.
24
Du, Plessis Marilize. "Fibromyalgia : association between specific psychological variables and functional status." Thesis, Stellenbosch : Stellenbosch University, 2005. http://hdl.handle.net/10019.1/70212.
Анотація:
Thesis (MA)--University of Stellenbosch, 2005.ENGLISH ABSTRACT: This study investigated the association between functional status in fibromyalgia patients and helplessness, self-efficacy, social support and cognitive appraisal. Patients' assessments of their pain and global severity of illness (as rated on a visual analog scale) as well as a physician's rating of global severity, tended to correlate with helplessness and pain-related self-statements. Patients' perceived change in difficulty and satisfaction regarding activities of daily living (measured by means of the Modified Health Assessment Questionnaire) correlated negatively with self-efficacy beliefs and relationship strain, while patients' subjective assessment of their global improvement was related to self-efficacy. The objective rating by a physician of tender points correlated with catastrophizing self-statements and opportunity for confiding.
AFRIKAANSE OPSOMMING: In hierdie studie is die verband tussen die funksionele status van pasiënte met fibromialgie en die belewing van hulpeloosheid, selfdoeltreffendheid, sosiale ondersteuning en bepaalde kognisies ondersoek. Pasiënte se beoordeling van hulle ervaring van pyn en die globale ems van hulle siekte (soos beoordeel met behulp van 'n visuele analoogskaal), asook die geneesheer se beoordeling van die ems van hulle siekte, het met hulpeloosheid en pynverwante kognisies gekorreleer. Hulle waarneming van die verandering in die uitvoerbaarheid van, en hulle tevredenheid met hulle daaglikse aktiwiteite (gemeet met die Modified Health Assessment Questionnaire) het negatief verband gehou met selfdoeltreffendheid en verhoudingstremmings, terwyl hulle globale beoordeling van die verbetering in hulle siekte met selfdoeltreffendheid gekorreleer het. Die objektiewe assessering deur 'n geneesheer van sensitiewe liggaamsareas het verband getoon met disfunksionele kognisies (katastrofering) en vertroue in ander.
25
Dixon, William. "The association between systemic glucocorticoid therapy and risk of infection in patients with rheumatoid arthritis." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97264.
Анотація:
Infection is a major cause of morbidity and mortality in patients with rheumatoid arthritis (RA). One factor contributing to the increased infection risk is glucocorticoid (GC) therapy.The risk of infection associated with GC therapy in patients with RA is addressed in two manuscripts for submission. The first is a systematic review and meta-analysis of GC-associated infection risk from randomised controlled trials (RCTs) and observational studies. Summary estimates of risk ranged from no increased risk (RCTs) to a two-fold increased risk (observational studies). Reasons for the discrepancy are discussed. The second is a nested case control analysis from a Canadian administrative database, addressing the question of whether GC therapy increases the risk of non-serious infection in patients with RA. It shows that GC therapy is associated with a modest relative, but high attributable, risk of non-serious infection.Les infections sont une des causes majeure de morbidité et de mortalité chez les personnes atteintes de polyarthrite rhumatoïde (PAR). L'utilisation de glucocorticoïdes (GC) dans le traitement de cette maladie est perçue comme étant un des facteurs pouvant contribuer à cette augmentation de risque. Le risque d'infection associé aux GC dans la PAR est abordé dans deux manuscrits. Le premier est une revue systématique avec méta-analyse d'essais cliniques randomisés et d'études observationnelles ayant présentés des résultats portant sur le risque d'infection associé aux GC dans la PAR. Les GC n'étaient pas associés à une augmentation du risque d'infection dans les essais cliniques randomisés alors qu'ils semblaient doubler ce risque dans les études observationnelles. Les raisons pouvant expliquer ces différences sont évoquées. Le second manuscrit est une étude cas-témoins nichée dans une cohorte provenant d'une banque de données administratives canadienne et ayant pour but d'évaluer si les GC augmentent le risque d'infection non grave dans la PAR. Dans cette étude, les GC étaient associés à une augmentation légère du risque relatif mais considérable du risque attribuable d'infection non grave.
26
Hung, Chao-Ming, and 洪朝明. "A Study of Internet Patients Association to Breast Cancer Patients at E hospital." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/76051451193927203717.
Анотація:
碩士國立中山大學
高階經營碩士班
100
Abstract Due to the advanced development of information technology, society groups generated from internet have been in shear progress. Not only can this phenomenon establish a bridge of emotional connection, it can also provide health information and medical knowledge. Moreover, it certainly can be influential on health policy conducted by governments. Among the present medical society groups, PatientsLikeMe.com (PLM) developed an innovative business model. It built up a platform which allows patients share their own medical history. Through sharing medical history, the patients are able to discover someone else who has similar symptoms and then help to improve clinical outcome. This website may collect patients’ information under patients’ permission. After being clearly filed and analyzed, the data may be sold to medical companies or co-operated institutions for improving clinical therapy. This model has been evaluated by an American consulting institution on business model -- “Board of Innovation” --as the “Top 10 shocking Business Model of 2010”.Additionally, this model is recognized as a specific research model that may permanently change the methodology of medical research.(J Gospel Net December 2nd,2010) With a view to evaluating the function of websites on helping breast cancer patients to overcome depression and helplessness on diseases, in this study, we would like to introduce the concept of PLM internet society groups. After two interviews on breast cancer patients, we found that the patients are desperately looking for information while the diagnosis is firstly confirmed. These patients are thereby paying deep sympathy to the ones who are also in the same shoes. Under this condition, the patients are willing to share their experience anonymously. At the same time, they only want to solve the problems that already come to the door rather than prepare in advance. Consequently, all the information is collected from the surroundings and lack of proved quality. Therefore, it is important to avoid the fear brought by the overloaded information. From this research, we concluded that (1) during treatment, the breast cancer patients can receive professional assistance and sharing experience from PLM or similar function/ service on websites. (2)Through internet technology, it is possible to provide a platform that surpasses the limitation of both time and space and allows patients to share their personal experience and medical history. (3) PLM system opens a window that allows physicians or nurses to answer patient’s question in one-to-one manner. It is also possible for patients to share their knowledge and some tips that may not be mentioned by medical professionals. However, we also notice that most patients still have problems on using internet society groups because of time limitation, incapability of typing and being unfamiliar on internet skills etc. This research concludes that internet society groups are unlikely to fulfill the requirement of breast cancer patients. Key Word：PatientsLikeMe.com (PLM), Case Manager, Social Networking.
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Huang, Cheng-Fu, and 黃正富. "The influence of patient support groups on physical, psychological, social function in female cancer patients in Kaohsiung cancer patients association." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/9sq56k.
Анотація:
碩士國立中山大學
企業管理學系醫務管理碩士班
107
In Taiwan, the malignant neoplasm is always the top of ten leading causes of death since 1982. In the light of this, strategies for cancer prevention and treatment are crucial national policies. Cancer screening, treatment, case tracking, cancer registry are all important points in the strategies. In addition to clinical treatment, personal psychological support and social function maintain are also important for cancer patients. Therefore, the patients support group could play a key medium, which not only bring psychological and social support to the patients but also exert positive influences on the diseases. Such holistic care will help the patients to obtain better outcomes and aid the country to promote policy effectively. In this study, 220 female cancer patients in the patients support group were enrolled. The self-consciousness of the participants were investigated before and after joining the patients support group. We analyzed the samples using descriptive statistic to investigate the influence of joining the patients support group on the self-consciousness, the benefit of the activities hold in the patients support group, the person whom the patient mostly expected to give her support, and the person who supported the patient actually. Then, we used the pairs-T test to analyze the differences of the patients’ psychological state and social function before and after participating in the patients support group. Finally, we applied the ANOVA to analyze the effects of age, marital status, living area, occupation, disposable income, education degree on the patients’ physical, psychological state and social function before and after joining the patients support group. Most female cancer patients in this study were breast cancers(63％). The majority of patients in this study were enrollment period more than four years to five years (44％), age of 51-60 (44％), married (44％), living in Kaohsiung or Pingtung (97％), housewife (52％), senior high school or vocational high school (41％). Over 90％ patients thought that their self-consciousness significantly improved after joining the patients support group. Among the activities, patients thought that the " medical lectures" and " tourism activities " were the most helpful ones. During the illness, the first three order of people whom patients expected to support them were children, spouse, and siblings; the wardmates were at the fifth position. However, actually, the top three order of people who really gave a support to the patients were children, spouses, and wardmates. As a result, the support provided from the wardmates even exceeded that provided from the parents and siblings. Most demographic variables do not directly affect the self-consciousness. To compare whether joining the patients support group or not, there are no significant differences in psychological state, but there are significant differences in social function after joining the patients support group. The results of this study showed that the patients support group was quite important for the patients. Therefore, we hoped that the government can practically stand by the development of the patients support group by raising related policies regarding medical institutions and public health and expected these would bring up the beneficial outcomes for cancer patients and cancer prevention and treatment strategies.
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Ho, Chi-Han, and 何積翰. "Association of Erythrocyte Deformability With Anemia in Hemodialysis Patients." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/45830489288483869850.
Анотація:
碩士國立陽明大學
生醫光電工程研究所
98
A report by the United States Renal Data System in 2009 indicates that the incidence of End Stage Renal Disease in Taiwan is among the highest in the world. For patients suffering from serious renal disease, hemodialysis is the most common method of dialysis therapy worldwide. In hemodialysis, blood purification of uremic patients is achieved by urine detoxification through artificial kidney. We applied jumping optical tweezers to trap and stretch individual human erythrocytes (or red blood cells, RBCs) to measure the RBC deformability and to study the correlation between the RBC deformability and the “seriousness” of renal disease as well as its correlation with the effect of hemodialysis treatment. In our jumping optical tweezers system, a laser beam, diffracted by an acousto-optic modulator (AOM), was coupled into a high NA objective lens via appropriate optics to serve as the trapping beam. The focal spot was scanned discretely (or jumped) between two points by controlling the voltage of the radio-frequency (RF) driving the AOM. At a scanning frequency ~1kHz, the jumping focal spots served as a pair of parallel laser tweezers. With appropriate laser power and jumping distance, individual erythrocytes were trapped in the focal plane and stretched along the scanning direction and their deformability was measured. Besides, with a theoretical model, which allows us to calculate the stretching optical force as a function the jumping distance, in conjunction with the experimental data on the corresponding stretched length of the RBC’s major axis, the effective elastic constant of each individual RBC was determined. By comparing the deformability and the effective elastic constant of individual RBC samples from both healthy people and also from patients with uremia, we found that compared with healthy people, the deformability of RBCs of patient with uremia is slightly lower, and the effective elastic constant is slightly higher. Comparing the RBC deformability for patients with uremia before and after hemodialysis treatment, we found that the deformability increased, and the elastic constant decreased after hemodialysis treatment. Approximately 90% of the sever uremia patients also suffer from anemia, and clinically, the severity of anemia is judged by hematocrit %. Our results also indicate that the more severe the anemia patients (based on hematocrit %) the larger the decrement in RBC effective elastic constant after hemodialysis treatment.
29
Lin, Chieh-Nan, and 林界男. "Association between Valproic Acid and Metabolic Syndrome in Schizophrenic Patients." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/wvdjc6.
Анотація:
碩士國立陽明大學
公共衛生研究所
100
Objectives: This study wants to understand the association between valproic acid and metabolic abnormality in schizophrenic or schizophrenic patients. Besides, we also try to analyse the interactional effect of valproic acid and atypical antipsychotics on metabolic abnormality. Methods: This is a hospital-based, cross-sectional study. The study collects the data of schizophrenic or schizoaffective inpatients in rehabilitation or day ward on July of 2010. We use AHA/NHLBI modified ATP III criteria to make the diagnosis of metabolic syndrome. The analysis method of demographic, anthropometric and metabolic parameter is descriptive analysis. Chi-square test and multiple logistic regression are used to test the association of antipsychotics, valproic acid and metabolic syndrome or its individual components. Results: There are 323 patients enrolled in this study. The overall prevalence of metabolic syndrome is 35.3%. Female have significant higher risk of metabolic syndrome, waist abnormality and HDL abnormality then male. The odds ratio is 1.77 (95% C.I. 1.09-2.87), 3.03 (95% C.I. 1.85-4.95) and 2.83 (95% C.I. 1.71-4.69) respectively. Patients who takes valproic acid have higher risk of metabolic syndrome and waist abnormality. The odds ratio is 2.20 (95% C.I. 1.04-4.69) and 2.27 (95% C.I. 1.02-5.02). Compared to the patient under 30 years old, the odds ratio of metabolic syndrome in 31-40, 41-50 and over 50 year-old patients are 4.46 (95% C.I. 1.05-10.76), 3.35 (95% C.I. 1.38- 8.16) and 4.43 (95% C.I. 1.72-11.42) respectively. No significant difference in metabolic syndrome and its individual components whether the patients take olanzapine or clozapine or not. Conclusions: Female have significant higher risk of metabolic syndrome, waist abnormality and HDL abnormality then male. Valproic acid is associated with metabolic syndrome and waist abnormality. Older patients may have higher risk of metabolic syndrome. Key words: valproic acid, schizophrenia, metabolic syndrome, antipsychotics
30
Yang, Ju-Lan, and 楊茹蘭. "Association between Antipsychotic Agents and Primary Polydipsia in Psychiatric Patients." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/65533110814997542743.
Анотація:
碩士高雄醫學大學
藥學研究所碩士在職專班
101
【Background】 Primary polydipsia is a syndrome in which a person intakes fluids substantially beyond physiologic need due to obscure reasons unrelated to normal thirst or homeostatic needs. Polydipsia is commonly associated with chronic psychiatric illness. Psychotic patients with polydipsia can produce morbidity and possibly death due to hyponatremia and water intoxication. The aim of this study was to determine the clinical and socio-demographic factors of polydipsia in psychotic inpatients and to evaluate the association between prescribed antipsychotic drugs and this disorder. 【Method】 A retrospective survey of psychiatric inpatients during 2010-2011 at a mental hospital was done. The basic and clinical data of the subjects were collected from medical records. We examined and analyzed the difference of medical, demographic factors and prescribed psychotropic agents in this population. 【Result】 A total of 134 psychiatric inpatients were included, in which 67 cases were polydipsia. Prevalence of polydipsia in psychotic inpatients was 5.58%. The group with polydipsia was significantly having longer mental illness duration, more frequently having schizophrenia diagnosis, smoking habits and hyponatremia episodes, compared to the group without polydipsia. The study also found, prescribed anticholinergic agents and antipsychotic polypharmacy were significantly different among polydipsia and non-polydipsia patients. The two groups did not differ in marital status, education level, drinking habits and the types of prescribed antipsychotic agents. 【Conclusion】 Our findings suggest that primary polydipsia is not infrequent among the patients with chronic schizophrenia. Polydipsia might induce life-threatening complications in this population; nevertheless, it is remarkable how little sound information has been acquired about the treatment of these conditions. To recognize the sign of polydipsia become an important issue.
31
Hung, Kuan-Chun, and 洪冠群. "Multiple Minimum Support Association RuleMining for Hospitalization Prediction ofHemodialysis Patients." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/10140955935203508671.
Анотація:
碩士國立東華大學
資訊工程學系
92
In Taiwan, the rate of Hemodialysis (HD) therapy has been increased yearly for the patients of end-stage renal disease, with 1,241 per million populations. Currently, both the rate of population and occurrence rank the second highest among the world, just blow Japan and U.S.A separately. Due to the special characteristic of those patients, the admission times and the cost of per admission are higher than others, with 2.35 admission/year and 29.53 day/admission. From the prevention medical point of view, it could decrease dramatically both the admission rate and the cost by analyzing the HD lab data, finding the possible factors of admission and preventing ahead of time. Moreover, the Bureau of National Health Insurance of Taiwan will implement global budget system in 2004. For medical institutions, reducing cost and increasing profits result from effectively preventing disease from happening. Therefore, how to find out the cause and effect factors by analyzing HD lab data to reduce admission rate can reach the goal of both internal and external services for medical institutions. This study, through analyzing the HD lab data and related field knowledge, improves multiple minimum support algorithm for association rule mining to effectively increase the accuracy of the results for medicare and to shorten the analyzing period. The study shows that data mining not only results in high quality of medicare, but also performs effectively in cost control, especially for the case of end-stage renal disease patients. Under the pressure of how to integrate various annual plans, effectively utilize resources, and continue to seek quality improvements, this study is valuable for medical institutions.
32
CHEN, LIANG-YU, and 陳亮宇. "The Association Between H2 Blocker And Dementia In Elderly Patients." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/5u44t6.
Анотація:
碩士國防醫學院
公共衛生學研究所
106
As life expectancy of people in Taiwan grows, the number of people with dementia increases year by year. The social cost of dementia can not be underestimated. Therefore, it is an important health issue to prevent the occurrence of dementia. H2 blocker is the first-line medication for treating gastric ulcers. However, the habits of using medicines in combination with stomach medicines in Taiwan have led to an increasing abuse of H2 blocker. Recent studies have shown that long-term use of H2 blocker may contribute to vitamin B12 deficiency, and vitamin B12 deficiency may increase the risk of dementia. The purpose of this study was to investigate the association between H2 blocker and dementia in elderly patients. This was a retrospective population-based cohort study for 14 years and using the Taiwan Health Insurance Database 2000 (LHID2000). This study included elderly populations over 65 years old. The study population was divided into exposure group of H2 blocker and non-exposed group who did not use H2 blocker. These two groups were 1:1 matched by age, sex and comorbidities and were all followed until the occurrence of dementia, death, withdrawal from National Health Insurance program or until December 31, 2013, which occurred first. The Kaplan-Meier survival curve was used to understand the difference between the dementia in patients using and not using H2 blocker. The Cox regression was used to estimate hazard ratios (HRs) and 95% confidence interval (CI) for the risk of incident dementia. The study found that the risk of dementia in the elderly over the age of 65 who used the H2 blocker was significantly greater than that of the elderly group who did not use the H2 blocker (Adjusted HR = 2.46, 95% CI 1.99-3.05). In terms of dose effects, the low exposure group was 1-180 DDD (Adjusted HR = 2.42 95% CI, 1.88-3.10), and the exposure group was 180-540 DDD (Adjusted HR = 2.58, 95% CI, 2.04-3.26). The exposure group was greater than 540 DDD (Adjusted HR = 2.35, 95% CI, 1.81-3.04), and there was no significant dose-dependent. There was risk in the elderly population who took the H2 blocker. The results of this study showed that the use of H2 blocker is significantly associated with the risk of dementia in elderly patients. Therefore, it is recommended that patients avoid over using H2 blocker.
33
Lekalakala, Azania. "Delirium in critical Ill patients and association and its and its association with patient factors and factors and outcomes in adult intensive care units." Thesis, 2018. https://hdl.handle.net/10539/27718.
Анотація:
A research report submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg in partial fulfilment of the requirements for the degree of Master of Science in NursingBackground: Delirium is a frequent problem in the intensive care unit and associated with increased mortality, prolonged duration of ICU stay and increased cost. Failure by health care professionals to recognise the developing signs of delirium may have an adverse effect of long-term outcomes (quality of life, cognitive decline and independent functionality). Global guidelines have been developed for the early detection and management of delirium. It is argued that routine nurse-led screening for delirium using a validated screening tool will allow early detection and timely implementation of management strategies that reduce severity and/or duration. No studies to date were found in the South African setting on this topic. Without this essential information, appropriate and suitable nursing interventions for delirium will not be able to be developed. Therefore this South African study intended to explore the incidence of delirium in critically ill patients in the adult intensive care units. Setting: The setting for this study was the adult intensive care units of a 1,200 bedded university affiliated public hospital and tertiary level institution in Johannesburg. These intensive care units were: trauma and general intensive care units. Aim: The purpose of this study was to determine the incidence of delirium in critically ill patients in the adult intensive care units of a university-affiliated public hospital in Johannesburg, and to explore the relationships between delirium, patient clinical factors and outcomes. Design and Methods: A quantitative-descriptive and longitudinal design was utilised in this study. The total sample comprised 82 (n = 82) patients from the ICUs between the period 1.07.2017 to 30.9.2017. Random sampling method was utilised. Data was collected by means of a researcher developed checklist built on items from two validated questionnaires: Richmond Agitation and Anxiety Scale (RAAS) and Confusion Assessment Method for ICU (CAM-ICU). Results: Overall 82 (n = 82) patients participated in this study, and more than one-third tested positive for delirium when CAM-ICU method was used during their length of stay in ICU. It should be noted that two-thirds of the sample of patients were surgical cases, and average length of stay in ICU was 6 days. Six patients who had delirium had a death outcome after 218 days in ICU, but these results showed no statistical significance (IR 2.62; CI 0.56 – 16.10; p=0.916). Eight clinical factors in this study were statistically significantly (p<0.000) associated with patients having delirium or not, and most important were medication (p=0.030), physical restraint (p=0.025), and severity of critical illness (p<0.001). Further, the characteristics of >60 years of patients who had tested positive for delirium were mostly male (83.3%), with tertiary level education (50.0%), and on midazolam medication (83.3%). Clinical Implications: These findings have implications for nursing care because they highlight the importance of regular screening for delirium and addressing modifiable factors that contribute to delirium, such as the use of physical restraint and medication titrations. Conclusion: These findings suggest patients are at risk for delirium in these ICUs, and current best practice measures to prevent or combat the incidence of delirium should be put into place.
XL2019
34
Mong-Slezak, Elaine. "Association of patient to nurse ratio and hand washing stations and infection-related hospitalizations in hemodialysis patients." Thèse, 2018. http://hdl.handle.net/1866/21609.
35
Liu, Ching Yi, and 劉靜宜. "The Association of Loyalty, Prognoses, Medical Consumptions among Diabetes Mellitus Patients." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/32332133030923779049.
Анотація:
碩士長庚大學
企業管理研究所在職專班
97
Diabetes Mellitus is a common and major chronic disease among Taiwanese population. According to statistics in 2008, it was counted as the fifth place of top ten leading cause of death in Taiwan. Medical expenditures related to diabetes represent about 10% of expenditures in Taiwan National Health Insurance. Diabetes Mellitus has large influence for the health of residents and medical consumptions. Such chronic diseases are required a constant and stable quality of care for their long term medical quality and effectiveness of care. Therefore, patient loyalty and compliance of medical behavior are especially important among such patients. The study aims to explore the factors associated with patient loyalty and the subsequent medical quality and consumptions in Diabetes Mellitus patients in Taiwan. The study has selected Diabetes Mellitus patients visiting a clinic center in Taipei as samples to examine the hypotheses. Total number of study subjects was 3506 recruited from January, 2005 to December, 2007. The statistical methods used in the analysis were two-sample t test, linear regression, and Cox proportional hazard model. The findings of this study are summarized as follows. 1. Patients with relatively low-loyalty behavior were found to have characteristics of non- using refill prescription, none chronic complications, cardiovascular disease, endocrine/metabolic complications, 2. Higher hospitalization and incidence of major chronic complications were found in less loyalty patients. 3. The medical consumptions of the lower loyalty are the highest among study groups. The study has suggested that a stable and loyal medical behavior will benefit patient medical quality and efficiency of health care system among DM patients. A well designed network of primary care system is required in the future health care system. Physician-patient relationship together with quality measurement in evaluation of care quality is suggested in the prospected policy making.
36
Wu, Shao-Ying, and 吳紹瑩. "The Association between Antihistamines and Acute Urinary Retention Among Elderly Patients." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/08055903502944655060.
Анотація:
碩士國立成功大學
臨床藥學研究所
97
Background Acute urinary retention (AUR) is a common clinical emergent condition. The incidence of AUR increases with ages. Drugs with potent anticholinergic properties are not inappropriate for elderly patients according to Beers’ criteria. These drugs include first-generation antihistamines, tricyclic antidepressant agents, antispasmodics, and muscle relaxants. However, these medicines are still widely used among elderly patients. Therefore, the aim of this study is to evaluate the association between antihistamines and AUR in elderly patients. Method The data source is from non-sampled National Health Insurance in 2003~2004. The case group was defined as elderly patients with the first AUR event between 1 Jan 2004 and 31 Dec 2004. The control group is defined as elderly patients without AUR during 2004. Control subjects were matched to cases for age (±3years), gender, area, hospital level, the date of case included, and benign prostatic hyperplasia. After matching, we analyzed the risk of AUR in elderly patients who took antihistamines. The use of antihistamines is defined as current use (antihistamines within 7 days), past use (within 8~30 days) and no use (did not use antihistamines within 30 days). Result We identified 5,164 case patients and 36,894 control patients after matching. More patients have covariant factors of cardiac disease (27.35%), diabetes mellitus (18.55%), and NSAID (17.88%). Current antihistamine use was associated with an increased risk of AUR (adjusted OR, 2.220 [95% CI, 1.981~2.488]). Both first-generation (adjusted OR, 2.746 [95% CI, 2.408~3.132]) and second-generation (adjusted OR, 1.385 [95% CI, 1.108~1.731]) antihistamine use increased the risk of AUR significantly. Compare to first-generation antihistamines, second-generation antihistamines had lower risk of AUR (adjusted OR, 0.384 [95% CI, 0.197~0.748]). Conclusion Both first-generation and second-generation antihistamine therapy in the elderly patients within 7 days were associated with an increased risk of AUR. In addition, second-generation antihistamines had lower risk of AUR compared with first-generation antihistamines.
37
Su, Bei-Yi, and 蘇倍儀. "Association of DISC1 genetic variances with social cognition in schizophrenia patients." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/08115610694793360674.
Анотація:
碩士國立成功大學
行為醫學研究所
97
Patients with schizophrenia exhibit impaired social cognitive functions; however, the molecular mechanism of this deficit remains unclear. DISC1, a promising susceptibility gene of schizophrenia, is associated with social behaviors in rodents. Moreover, a robust relationship among a common nonconservative SNP (Ser704Cys) of DISC1 vs. cognitive functions and brain morphology had been reported. Based upon the findings, current study aimed to investigate the potential association between DISC1 genetic variances and social cognitions in patients with schizophrenia. One hundred and fifteen patients with chronic schizophrenia, who had been stabilized with antipsychotic treatment, were assessed with neurocognitive instruments, including the emotion perception and management components of Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT) for social cognition, and genotyped for the DISC1 Ser704Cys SNP. We found that patients with the DISC1 Cys/Cys genotype had poorer emotion perception, but not emotion management, than the Ser-allele carriers (Ser/Ser and Cys/Ser). This finding suggests that genetic variation in DISC1 may contribute to the social cognitive deficit, particularly emotion perception, in patients with chronic schizophrenia.
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Hsu, Hsiao-Yuan, and 徐筱媛. "Association of Emotion Perception with DRD3 Ser9Gly Polymorphisms in Schizophrenia Patients." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/61757368210392572059.
Анотація:
碩士國立成功大學
行為醫學研究所
97
Abstract Objective: Impaired social cognition, particularly emotion perception, is an essential feature of schizophrenia, but its molecular mechanism remains unclear. Previous study demonstrated that the dopamine D3 receptor was relevant to emotion activity and social behavior in rodent. Among the variances of D3 receptor gene (DRD3), the Ser9Gly polymorphism is associated with social function of patients with schizophrenia. This polymorphism may be also related with their emotion perception, a major domain of social cognitive functions. Methods: To explore this potential molecular underpinning of social cognition, the DRD3 polymorphism is investigated in one hundred and eighteen chronic schizophrenia patients who had been stabilized with optimal antipsychotic treatment. The social cognition was evaluated by section A (facial emotion perception) of the Mayer–Salovey–Caruso Emotional Intelligence Test. Results: The Ser/Gly group of patients was superior in emotion perception (p=0.036) while the potential contributing variables of age, gender, typical/atypical antipsychotics, positive and negative symptoms, and delayed recall memory were controlled for. The Ser9Gly polymorphism also tended to affect delayed verbal memory. Conclusion: In conclusion, the DRD3 Ser/Gly variance may play an important role in facial emotion perception in patients with schizophrenia. Key words: Dopamine receptors, social cognition, MSCEIT, schizophrenia, emotion perception
39
Lin, Wu-Hu, and 林五湖. "Association of Psychological Adaptation and Quality of Life among Stroke Patients." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/21688697433545848095.
Анотація:
碩士亞洲大學
健康產業管理學系健康管理組碩士在職專班
102
Background: Stroke is the main cause of mortality and long-term disability and the impacts on physical, psychological and social consequences are often accompanied with the survivors, and thus affects their quality of life dramatically. Because the development of medical technology and improvement of medical care quality, the mortality of strokes gradually declines. The stroke survivors who suffer from disability continue to increase. Therefore the research about quality of life among stroke patients becomes more and more important. The “Selection, Optimization and Compensation”(SOC) model, one of the successful aging theories, describes the psychological adaptation process for the individuals when their physical function decrease with aging. Stroke patients, just as the disabled elderly, need to manage the influence of long-term disability through psychological adaptation. The present study applies the SOC model to examine the psychological adaptation of stroke patients and to explore its relationship with quality of life. Method: The participants were recruited from the outpatients of the rehabilitation department in a regional teaching hospital in central Taiwan. The data were collected by face-to-face structured questionnaire interviews, including demographic characteristics, stroke severity, ADL function, depression, cognition function, quality of life and psychological adaptation. Psychological adaptation based on SOC model covered the dimensions of Elective selection, Loss-based selection, Optimization, and Compensation. In total there were fifty-one participants finished the interviews. Results: Quality of life were moderate positive associated with psychological adaptation (r=0.305) for the stroke patients. The results of stepwise regression analysis showed that the higher elective selective adaptation was related to higher total quality of life (β=3.766). From the perspective of each dimension of quality of life, the higher elective selection adaptation of the stroke patients, the higher environmental quality of life (β=1.243) and higher social relation-related quality of life (β=0.358) they had. The higher compensational adaptation they had, the higher physical quality of life they would enjoy (β=1.372). Conclusion: Our findings show psychological adaptation was an important determinant of quality of life. Among different types of psychological adaptation, elective selection was most effective to quality of life, and compensational adaptation would help the stroke patients to achieve their rehabilitation goal. We suggest that taking psychological intervention into considerations in the present medical care model and future health policy decision. The patients' health will be improved comprehensively.
40
Silva, Joana Inês Alves da. "Association of admission hematocrit with mortality in critical care surgical patients." Master's thesis, 2016. https://repositorio-aberto.up.pt/handle/10216/89488.
41
Chen, Hui-Lee, and 陳惠琍. "Association between TZDs use and cancer onset among patients with diabetes." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/12709724834561817262.
Анотація:
碩士中國醫藥大學
醫務管理學系碩士在職專班
100
Background: Diabetes and cancer are common chronic diseases with tremendous impact on health worldwide.Type 2 diabetes and cancer have many common risk factors complicated. Oral hypoglycemic drugs for type 2 diabetes, is the primary treatment, one of drugs is the Thiazolidinedione (TZDs). Adverse events occurred one after another of these drugs. The U.S. Food and Drug Administration (FDA) is informing the public that“use of the diabetes medication Actos (pioglitazone) for more than one year may be associated with an increased risk of bladder cancer”, shocked the world medical, making panic with endocrinologist and patients. Current association between TZDs use and cancer onset among patients with diabetes, a large nationally representative study is still small. Especially in the Asian diabeties data with taking TZDs and cancer related research, it is missing. Objectives: To explore association between TZDs use and bladder cancer, colorectal cancer or other cancers onset among patients with type 2 diabetes by National Health Insurance (NHI) database. Methods: A random sample of 1,000,000 people insured by the NHI in 2005 was created by the National Health Research Institute for academic research.To study on National Health Insurance database from 2002-2009. Study for the use of hypoglycemic drugs TZDs and ICD-9-CM primary diagnosis, secondary diagnosis, and the third diagnosis code 250.00- 250.93 of diabetes, with greater than 40 years of age. The results of 27,382 patients, of which 14,748 were males, 12,634 were females. By Chi-square test , binary logistic and multinomial logistic analysis. Results: The study found that gender, age, duration of diabetes, severity of diabetes, TZDs use and hospital level influence patients with diabetes taking TZDs risk of colorectal cancer , bladder cancer and other cancers. Showed that males with age over 50 years as the age increases the risk of bladder cancer or colorectal cancer is positively related and the odds ratio of 2 to 9 times for the age of 40-49 years. Duration of diabetes 1-2 years and TZDs period of 3 years than those with less than one year are more than one times higher than the risk ratio. Most patients with cancer choose Medical Center for cancer treatment. Those with severity of disease and severe up to 3-4 times more than the mild risk of cancer. Conclusion: Type 2 diabetes taking TZDs drugs for 1-2 years have high risk of suffering from bladder cancer, colorectal cancer and other cancers, elderly and disease severity were severe for the high risk group. Recommended that the Department of Health is considering TZDs withdrawal or to be used TZDs drugs were given over 3 years free bladder cancer screening and regular follow-up to ensure public safety and reducing medication health insurance expenses.
42
Shu-FenWang and 王淑芬. "Association between Sexual Dysfunction and Diabetes Control in Patients with Diabetes." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/59843686313597470896.
Анотація:
碩士國立成功大學
護理學系碩博士班
101
Background: There are 371 million patients of diabetes in the world and sexual dysfunction is the common problem caused by diabetes. Sexual health is part of care for patients. However, it tends to be neglected and it results in low self-esteem and impact on quality of life. Research Purposes: This study aims to probe into prevalence rate of sexual dysfunction caused by diabetes and correlation between diabetes control and sexual dysfunction. Research Method: By cross-sectional method, this study collected and investigated diabetes patients’ data in one medical center of Tainan through convenience sampling. Structural questionnaire includes demographic variables, IIEF and FSFI. By review of case reports, this study conducted correlation analysis on ten diabetes control data suggested by American Association of Diabetes Educators. Results: There are 224 participants of diabetes (124 males and 100 females)1u4u,4. Prevalence rate of sexual dysfunction of diabetes for males is 55.8%. Sexual dysfunction of diabetes for females is 63.8%. As to correlation between diabetes control and sexual dysfunction, eGFR and smoking have significant correlation. Conclusion: Prevalence rate of sexual dysfunction of diabetes is high for males or females. eGFR and smoking are related to sexual dysfunction. Prevention of nephropathy for patients with abnormal kidney functions and quitting of smoking for smokers should be reinforced to discovery the problems and have intervened treatment.
43
An-ChenChen and 陳安貞. "The association of masculinity with intimate relationship among erectile dysfunction patients." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/52y627.
44
Cheng, Hsiao-Wei, and 鄭曉薇. "Association between frailty and postoperative delirium in open heart surgery patients." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/75d292.
45
Silva, Joana Inês Alves da. "Association of admission hematocrit with mortality in critical care surgical patients." Dissertação, 2016. https://repositorio-aberto.up.pt/handle/10216/89488.
46
Fan, Ching-Wen, and 范靚文. "Factor affects stroke patients mortality and it’s association with ICU LOS." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/zagnyt.
47
Yang, Sheng, and 楊陞. "Association of LASP1 gene polymorphism and cognitive functions in schizophrenia patients." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/c5ue58.
48
Ryan, Marian. "Care coordination for senior patients with multiple chronic diseases : examining the association between organizational factors and patient outcomes /." 2010.
49
Wu, Pei-chun, and 吳珮君. "Association between Adherence of Statins and Cardiovascular Event in High Risk Patients." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/57930679817464656347.
Анотація:
碩士國立成功大學
臨床藥學研究所
96
Background: Until now, cardiovascular disease is still one of the major causes of death. To prevent cardiovascular disease has become an important issue. Many studies have proved that statins can not only effectively control hyperlipidemia but also help to prevent cardiovascular disease. However more and more studies have shown that the adherence of statins and cardiovascular disease prevention is highly related. The mortality of patient with low compliance is higher by 8 % than that of patients with high compliance. There are a lot of factors which may affect compliance, including the knowledge about statins, income, and the interaction between health care provider and patients. In Taiwan, statins has accouted for large part of National Health Insurance expenditure. Therefore, it is important to investagate the association between adherence of statins and cardiovascular disease. Objective: To analyze the association between adherence of statins and cardiovascular disease. Method: Our study design is a retrospective cohort study. The data source is from National Health Insurance in 2000~2004. Our subjective is patients with first cardiovascular disease in medical center used statins in 90 days after discharge.Use medication possession ratio (MPR) to present adherence, the calculation of MPR: MPR= (statins prescribed days) /365 days (365days as followed duration)x100%, define >80% as high MPR, 79~40% as moderate MPR, and <40% as low MPR. The endpoint is the readmission of cardiovascular disease Result: After calculating the one year MPR, in CHD group, there were 1196 persons in high MPR group, 1170 persons in medium MPR group and 1414 persons in low MPR group. And in ischemia stroke group, there were 412 persons in high MPR group, 604 persons in medium MPR group and 908 persons in low MPR group. The event rate of each group were 22.91%，30.26%，29.68% in CHD group and 4.48%，14.22%，54.24% in ischemia group. Used survival analysis to analyse the relationship between adherence of statins and readmission rate of cardiovascular disease, the hazard ratio of MPR in CHD group was 1.038 (P=0.6085), after ajustment the hazard ratio was 1.011 (P=0.8836), and the hazard ratio of MPR in ischemia stroke group was 1.038 (P=0.6085), after ajustment the hazard ratio was 1.011(P=0.8836). Furthermore our study analysed the readmission risk of different MPR by logistic regression. In CHD group, the odds ratio of moderate MPR group, compared to high MPR group, was 1.373 (P=0.0437), after ajustment the hazzar ratio is 1.326(P=0.0755), and the odds ratio group in low MPR group is 1.094(P=0.5677), after ajustment the hazard ratio was 1.05 (P=0.7521). In ischemia stroke group, the odds ratio of moderate MPR group, compared to high MPR group, was 1.562 (P=0.0526), after ajustment the hazard ratio was 1.552 (P=0.0584), and the odds ratio group in low MPR group was 2.130 (P=0.0003), after ajustment the hazard ratio is 2.131 (P=0.0004). Conclusion: Statins can effectively prevent readmission of cardiovascular disease. And compliance is the key point of statins’ effect. No matter in CHD group or ischemia group, the worse the compliance, the higher the risk of cardiovascular disease.
50
Lu, Chia-Hui, and 盧佳慧. "Association between Resilience and Posttraumatic Stress Symptoms among Motor Vehicle Accident Patients." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/75861984952801960355.
Анотація:
碩士國立臺灣大學
心理學研究所
100
Resilience has been regarded as a trait and a dynamic process with that people exposed to significant adversities and threats can achieve positive adaptation. During the past decades, studies on the association between resilience and trauma often define those who have never developed psychaitric symptoms or improved to levels of no psychiatric symptoms after trauma as resilient individuals. Based on the resilience theory, the main purpose of our study was to investigate the association between posttraumatic stress disorder (PTSD) symptoms and resilience in motor vehicle accident (MVA) survivors. We expected to understand the dynamic process of resilience and verify whether resilience could help to alleviate PTSD symptoms and enhance quality of life. This study first examined the psychometric properties of the Chinese versions of Acute Stress Disorder Scale (ASDS) and Resilience Scale (RS). Participants were recruited from the National Taiwan University Hospital. One hundred and twenty two participants who had undergone MVA were administered with the Chinese versions of RS, ASDS, Posttraumatic Diagnosis Scale (PDS), Beck Depression Inventory-II (BDI-II), Beck Anxiety Inventory (BAI), NEO-FFI Neuroticism and Extraversion subscales, and Quality of life scale (QOL) within three month after the MVA. Results indicated satisfactory psychometric properties for the Chinese ASDS and RS. There was no significant correlation between injury severity and PTSD symptoms. Females had more anxiety and depressive symptoms than males. Moreover, pre-MVA resilience correlated negatively with depressive symptoms and positively with quality of life, but did not correlate with acute stress and anxiety symptoms. However, there was a curvilinear relationship between pre-MVA resilience and PTSD symptoms, suggesting that individuals who possessed high and low level of resilience before MVA tended to experience more PTSD symptoms. The pre-post MVA change score of resilience had negative correlation with hyperarousal, anxiety, and depressive symptoms, and had positive correlation with QOL. The limitations and implication of these findings are discussed, and recommendation for future research direction is thus suggested.