Статті в журналах з теми "AsCas12a"
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Ознайомтеся з топ-42 статей у журналах для дослідження на тему "AsCas12a".
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Ittiprasert, Wannaporn, Chawalit Chatupheeraphat, Victoria H. Mann, Wenhui Li, André Miller, Taiwo Ogunbayo, Kenny Tran, Yousef N. Alrefaei, Margaret Mentink-Kane, and Paul J. Brindley. "RNA-Guided AsCas12a- and SpCas9-Catalyzed Knockout and Homology Directed Repair of the Omega-1 Locus of the Human Blood Fluke, Schistosoma mansoni." International Journal of Molecular Sciences 23, no. 2 (January 6, 2022): 631. http://dx.doi.org/10.3390/ijms23020631.
Повний текст джерелаShebanova, Regina, Natalia Nikitchina, Nikita Shebanov, Vladimir Mekler, Konstantin Kuznedelov, Egor Ulashchik, Ruslan Vasilev, et al. "Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA." Nucleic Acids Research 50, no. 2 (December 24, 2021): 1162–73. http://dx.doi.org/10.1093/nar/gkab1227.
Повний текст джерелаPetiwala, Sakina, Apexa Modi, Tifani Anton, Erin Murphy, Sabah Kadri, Hengcheng Hu, Charles Lu, Michael J. Flister, and Daniel Verduzco. "Optimization of Genomewide CRISPR Screens Using AsCas12a and Multi-Guide Arrays." CRISPR Journal 6, no. 1 (February 1, 2023): 75–82. http://dx.doi.org/10.1089/crispr.2022.0093.
Повний текст джерелаSousa, Patricia, Tusneem Janoudi, Edouard deDreuzy, Mark S. Shearman, Kate Zhang, and Kai-Hsin Chang. "Preclinical Development of EDIT301, an Autologous Cell Therapy Comprising AsCas12a-RNP Modified Mobilized Peripheral Blood-CD34 + Cells for the Potential Treatment of Transfusion Dependent Beta Thalassemia." Blood 138, Supplement 1 (November 5, 2021): 1858. http://dx.doi.org/10.1182/blood-2021-149956.
Повний текст джерелаPattali, Rithu, Kaitlyn Izzo, Edward Goncz, Steven Sexton, Kevin Wasko, John Zuris, Michael Nehil, et al. "191 GAPDH knock-in of high affinity CD16 in iPSC derived NK cells drives high-level expression and increased anti-tumor function." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (November 2021): A203. http://dx.doi.org/10.1136/jitc-2021-sitc2021.191.
Повний текст джерелаLee Yu, Henson, Yumeng Cao, Xiao Lu, and I.-Ming Hsing. "Detection of rare variant alleles using the AsCas12a double-stranded DNA trans-cleavage activity." Biosensors and Bioelectronics 189 (October 2021): 113382. http://dx.doi.org/10.1016/j.bios.2021.113382.
Повний текст джерелаMarino, Nicole D., Jenny Y. Zhang, Adair L. Borges, Alexander A. Sousa, Lina M. Leon, Benjamin J. Rauch, Russell T. Walton, et al. "Discovery of widespread type I and type V CRISPR-Cas inhibitors." Science 362, no. 6411 (September 6, 2018): 240–42. http://dx.doi.org/10.1126/science.aau5174.
Повний текст джерелаYang, Zhao, Kun Zhang, Tianying Xing, Suhang Bai, Zongyi Shen, Luyao Wang, Lingzhi Wang, Zichen Zhang, Chong Li, and Wei Zhang. "Application of Clustered Regularly Interspaced Short Palindromic Repeat—Cas12a System in Cancer Research and its Structural Basis." Cancer Plus 4, no. 1 (January 25, 2022): 30. http://dx.doi.org/10.18063/cp.v4i1.240.
Повний текст джерелаVasilev, Ruslan, Natalia Gunitseva, Regina Shebanova, Aleksei Korzhenkov, Anna Vlaskina, Marta Evteeva, Irina Polushkina, et al. "Targeted Modification of Mammalian DNA by a Novel Type V Cas12a Endonuclease from Ruminococcus bromii." International Journal of Molecular Sciences 23, no. 16 (August 18, 2022): 9289. http://dx.doi.org/10.3390/ijms23169289.
Повний текст джерелаMa, Shufeng, Xinlong Wang, Yongfei Hu, Jie Lv, Chengfang Liu, Kaitong Liao, Xiaohua Guo, Dong Wang, Ying Lin, and Zhili Rong. "Enhancing site-specific DNA integration by a Cas9 nuclease fused with a DNA donor-binding domain." Nucleic Acids Research 48, no. 18 (September 28, 2020): 10590–601. http://dx.doi.org/10.1093/nar/gkaa779.
Повний текст джерелаMurugan, Karthik, Arun S. Seetharam, Andrew J. Severin, and Dipali G. Sashital. "CRISPR-Cas12a has widespread off-target and dsDNA-nicking effects." Journal of Biological Chemistry 295, no. 17 (March 11, 2020): 5538–53. http://dx.doi.org/10.1074/jbc.ra120.012933.
Повний текст джерелаZhang, Liyang, H. Tomas Rube, Christopher A. Vakulskas, Mark A. Behlke, Harmen J. Bussemaker, and Miles A. Pufall. "Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes." Nucleic Acids Research 48, no. 9 (April 21, 2020): 5037–53. http://dx.doi.org/10.1093/nar/gkaa231.
Повний текст джерелаWettengel, Jochen M., Lea Hansen-Palmus, Sofiya Yusova, Lauren Rust, Sreya Biswas, Julien Carson, Junghyun Ryu, Benjamin N. Bimber, Jon D. Hennebold, and Benjamin J. Burwitz. "A Multifunctional and Highly Adaptable Reporter System for CRISPR/Cas Editing." International Journal of Molecular Sciences 24, no. 9 (May 5, 2023): 8271. http://dx.doi.org/10.3390/ijms24098271.
Повний текст джерелаAllen, Alexander G., Samia Q. Khan, Kaitlyn M. Izzo, Mrunali Jagdale, Alexandra Gerew, Nadire R. Cochran, Jared Getgano, et al. "Abstract 562: AsCas12a gene-edited iPSC-derived NK cells constitutively expressing CD16 and membrane-bound IL-15 demonstrate prolonged persistence and robust anti-tumor activities in a solid tumor mouse model." Cancer Research 82, no. 12_Supplement (June 15, 2022): 562. http://dx.doi.org/10.1158/1538-7445.am2022-562.
Повний текст джерелаZhu, Dan, Junyi Wang, Di Yang, Jianzhong Xi, and Juan Li. "High-Throughput Profiling of Cas12a Orthologues and Engineered Variants for Enhanced Genome Editing Activity." International Journal of Molecular Sciences 22, no. 24 (December 10, 2021): 13301. http://dx.doi.org/10.3390/ijms222413301.
Повний текст джерелаHanna, Rabi, Haydar Frangoul, Christopher Mckinney, Luis Pineiro, Markus Mapara, Kai-Hsin Chang, Michael Jaskolka, et al. "S264: EDIT-301 SHOWS PROMISING PRELIMINARY SAFETY AND EFFICACY RESULTS IN THE PHASE I/II CLINICAL TRIAL (RUBY) OF PATIENTS WITH SEVERE SICKLE CELL DISEASE USING HIGHLY SPECIFIC AND EFFICIENT ASCAS12A ENZYME." HemaSphere 7 (August 2023): e05170e0. http://dx.doi.org/10.1097/01.hs9.0000967968.05170.e0.
Повний текст джерелаGerew, Alexandra, Steven Sexton, Kevin M. Wasko, Mark S. Shearman, Kate Zhang, Kai-Hsin Chang та Samia Q. Khan. "Deletion of CISH and TGFβR2 in iPSC-Derived NK Cells Promotes High Cytotoxicity and Enhances In Vivo Tumor Killing". Blood 138, Supplement 1 (5 листопада 2021): 2780. http://dx.doi.org/10.1182/blood-2021-150731.
Повний текст джерелаMaerken, Melanie, David MacEwan, Nicholas Harper, Joseph R. Slupsky, and Adam Linley. "Gene Editing of BTK in Acute Myeloid Leukaemia Using CRISPR-Cas9." Blood 132, Supplement 1 (November 29, 2018): 3952. http://dx.doi.org/10.1182/blood-2018-99-113804.
Повний текст джерелаAllen, Alexander G., Rithu Pattali, Kaitlyn M. Izzo, Jared A. Getgano, Kevin M. Wasko, Laura C. Blaha, John A. Zuris, Kate Zhang, Mark S. Shearman, and Kai-Hsin Chang. "A Bicistronic Vector Expressing CD16 and a Membrane Bound IL-15 Construct in iPSC Derived NK Cells Increased Cytotoxicity and Persistence." Blood 138, Supplement 1 (November 5, 2021): 4809. http://dx.doi.org/10.1182/blood-2021-153258.
Повний текст джерелаCetin, Ronay, Martin Wegner, Leah Luwisch, Sarada Saud, Tatjana Achmedov, Sebastian Süsser, Antonella Vera-Guapi, et al. "Optimized metrics for orthogonal combinatorial CRISPR screens." Scientific Reports 13, no. 1 (May 6, 2023). http://dx.doi.org/10.1038/s41598-023-34597-8.
Повний текст джерелаJacobsen, Thomas, Chunyu Liao, and Chase L. Beisel. "The Acidaminococcus sp. Cas12a nuclease recognizes GTTV and GCTV as non-canonical PAMs." FEMS Microbiology Letters 366, no. 8 (April 1, 2019). http://dx.doi.org/10.1093/femsle/fnz085.
Повний текст джерелаZhang, Liyang, John A. Zuris, Ramya Viswanathan, Jasmine N. Edelstein, Rolf Turk, Bernice Thommandru, H. Tomas Rube, et al. "AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines." Nature Communications 12, no. 1 (June 23, 2021). http://dx.doi.org/10.1038/s41467-021-24017-8.
Повний текст джерелаZhang, Yingxiao, Yanhao Cheng, Hong Fang, Nathaniel Roberts, Liyang Zhang, Christopher A. Vakulskas, Randall P. Niedz, James N. Culver, and Yiping Qi. "Highly Efficient Genome Editing in Plant Protoplasts by Ribonucleoprotein Delivery of CRISPR-Cas12a Nucleases." Frontiers in Genome Editing 4 (January 31, 2022). http://dx.doi.org/10.3389/fgeed.2022.780238.
Повний текст джерелаAn, Yi, Ya Geng, Junguang Yao, Chunxiang Fu, Mengzhu Lu, Chun Wang, and Juan Du. "Efficient Genome Editing in Populus Using CRISPR/Cas12a." Frontiers in Plant Science 11 (November 19, 2020). http://dx.doi.org/10.3389/fpls.2020.593938.
Повний текст джерелаZhu, Zhijian, Manyu Zhang, Dandan Liu, Defei Liu, Tao Sun, Yujing Yang, Jiacheng Dong, et al. "Development of the thermophilic fungus Myceliophthora thermophila into glucoamylase hyperproduction system via the metabolic engineering using improved AsCas12a variants." Microbial Cell Factories 22, no. 1 (August 11, 2023). http://dx.doi.org/10.1186/s12934-023-02149-4.
Повний текст джерелаKrishnamurthy, Sateesh, Christine Wohlford-Lenane, Suhas Kandimalla, Gilles Sartre, David K. Meyerholz, Vanessa Théberge, Stéphanie Hallée, et al. "Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia." Nature Communications 10, no. 1 (October 28, 2019). http://dx.doi.org/10.1038/s41467-019-12922-y.
Повний текст джерелаMaule, Giulia, Antonio Casini, Claudia Montagna, Anabela S. Ramalho, Kris De Boeck, Zeger Debyser, Marianne S. Carlon, Gianluca Petris, and Anna Cereseto. "Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing." Nature Communications 10, no. 1 (August 7, 2019). http://dx.doi.org/10.1038/s41467-019-11454-9.
Повний текст джерелаIlla-Berenguer, Eudald, Peter R. LaFayette, and Wayne A. Parrott. "Editing efficiencies with Cas9 orthologs, Cas12a endonucleases, and temperature in rice." Frontiers in Genome Editing 5 (March 17, 2023). http://dx.doi.org/10.3389/fgeed.2023.1074641.
Повний текст джерелаDeWeirdt, Peter C., Kendall R. Sanson, Annabel K. Sangree, Mudra Hegde, Ruth E. Hanna, Marissa N. Feeley, Audrey L. Griffith, et al. "Optimization of AsCas12a for combinatorial genetic screens in human cells." Nature Biotechnology, July 13, 2020. http://dx.doi.org/10.1038/s41587-020-0600-6.
Повний текст джерелаOkada, Satoshi, Goro Doi, Shitomi Nakagawa, Emiko Kusumoto, and Takashi Ito. "Simple-to-use CRISPR-SpCas9/SaCas9/AsCas12a vector series for genome editing in Saccharomyces cerevisiae." G3 Genes|Genomes|Genetics, August 30, 2021. http://dx.doi.org/10.1093/g3journal/jkab304.
Повний текст джерелаZhang, Liyang, John A. Zuris, Ramya Viswanathan, Jasmine N. Edelstein, Rolf Turk, Bernice Thommandru, H. Tomas Rube, et al. "Author Correction: AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines." Nature Communications 12, no. 1 (July 19, 2021). http://dx.doi.org/10.1038/s41467-021-24770-w.
Повний текст джерелаMaule, Giulia, Antonio Casini, Claudia Montagna, Anabela S. Ramalho, Kris De Boeck, Zeger Debyser, Marianne S. Carlon, Gianluca Petris, and Anna Cereseto. "Author Correction: Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing." Nature Communications 11, no. 1 (October 22, 2020). http://dx.doi.org/10.1038/s41467-020-19351-2.
Повний текст джерелаKnott, Gavin J., Brady F. Cress, Jun-Jie Liu, Brittney W. Thornton, Rachel J. Lew, Basem Al-Shayeb, Daniel J. Rosenberg, et al. "Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a." eLife 8 (August 9, 2019). http://dx.doi.org/10.7554/elife.49110.
Повний текст джерелаAgeely, Eman A., Ramadevi Chilamkurthy, Sunit Jana, Leonora Abdullahu, Daniel O’Reilly, Philip J. Jensik, Masad J. Damha, and Keith T. Gagnon. "Gene editing with CRISPR-Cas12a guides possessing ribose-modified pseudoknot handles." Nature Communications 12, no. 1 (November 15, 2021). http://dx.doi.org/10.1038/s41467-021-26989-z.
Повний текст джерелаWang, Yao, Tao Qi, Jingtong Liu, Yuan Yang, Ziwen Wang, Ying Wang, Tianyi Wang, et al. "A highly specific CRISPR-Cas12j nuclease enables allele-specific genome editing." Science Advances 9, no. 6 (February 10, 2023). http://dx.doi.org/10.1126/sciadv.abo6405.
Повний текст джерелаOoi, Kean Hean, Mengying Mandy Liu, Jie Wen Douglas Tay, Seok Yee Teo, Pornchai Kaewsapsak, Shengyang Jin, Chun Kiat Lee, et al. "An engineered CRISPR-Cas12a variant and DNA-RNA hybrid guides enable robust and rapid COVID-19 testing." Nature Communications 12, no. 1 (March 19, 2021). http://dx.doi.org/10.1038/s41467-021-21996-6.
Повний текст джерелаKim, Do Yon, Jeong Mi Lee, Su Bin Moon, Hyun Jung Chin, Seyeon Park, Youjung Lim, Daesik Kim, Taeyoung Koo, Jeong-Heon Ko, and Yong-Sam Kim. "Efficient CRISPR editing with a hypercompact Cas12f1 and engineered guide RNAs delivered by adeno-associated virus." Nature Biotechnology, September 2, 2021. http://dx.doi.org/10.1038/s41587-021-01009-z.
Повний текст джерелаSun, Ruirui, Yuqian Zhao, Wenjuan Wang, Jun-Jie Gogo Liu, and Chunlai Chen. "Nonspecific interactions between Cas12a and dsDNA located downstream of the PAM mediate target search and assist AsCas12a for DNA cleavage." Chemical Science, 2023. http://dx.doi.org/10.1039/d2sc05463a.
Повний текст джерелаBanakar, Raviraj, Mollie Schubert, Gavin Kurgan, Krishan Mohan Rai, Sarah F. Beaudoin, Michael A. Collingwood, Christopher A. Vakulskas, Kan Wang, and Feng Zhang. "Efficiency, Specificity and Temperature Sensitivity of Cas9 and Cas12a RNPs for DNA-free Genome Editing in Plants." Frontiers in Genome Editing 3 (January 12, 2022). http://dx.doi.org/10.3389/fgeed.2021.760820.
Повний текст джерелаWang, Yanchun, Shuli Sang, Xin Zhang, Haoxia Tao, Qing Guan, and Chunjie Liu. "Efficient Genome Editing by a Miniature CRISPR-AsCas12f1 Nuclease in Bacillus anthracis." Frontiers in Bioengineering and Biotechnology 9 (January 14, 2022). http://dx.doi.org/10.3389/fbioe.2021.825493.
Повний текст джерелаBigelyte, Greta, Joshua K. Young, Tautvydas Karvelis, Karolina Budre, Rimante Zedaveinyte, Vesna Djukanovic, Elizabeth Van Ginkel, et al. "Miniature type V-F CRISPR-Cas nucleases enable targeted DNA modification in cells." Nature Communications 12, no. 1 (October 26, 2021). http://dx.doi.org/10.1038/s41467-021-26469-4.
Повний текст джерелаHuang, Hongxin, Weiqi Lv, Jinhe Li, Guanjie Huang, Zhihong Tan, Yongfei Hu, Shufeng Ma, Xin Zhang, Linxuan Huang, and Ying Lin. "Comparison of DNA targeting CRISPR editors in human cells." Cell & Bioscience 13, no. 1 (January 16, 2023). http://dx.doi.org/10.1186/s13578-023-00958-z.
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