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Статті в журналах з теми "Apoptosis signal-regulating kinase 1"
Kim, Albert H., Gus Khursigara, Xuan Sun, Thomas F. Franke, and Moses V. Chao. "Akt Phosphorylates and Negatively Regulates Apoptosis Signal-Regulating Kinase 1." Molecular and Cellular Biology 21, no. 3 (February 1, 2001): 893–901. http://dx.doi.org/10.1128/mcb.21.3.893-901.2001.
Повний текст джерелаWilson, Kathryn S., Hanna Buist, Kornelija Suveizdyte, John T. Liles, Grant R. Budas, Colin Hughes, Margaret R. MacLean, et al. "Apoptosis signal-regulating kinase 1 inhibition in in vivo and in vitro models of pulmonary hypertension." Pulmonary Circulation 10, no. 2 (April 2020): 204589402092281. http://dx.doi.org/10.1177/2045894020922810.
Повний текст джерелаTobiume, Kei. "Characterization of Mouse Apoptosis Signal-regulating Kinase 1." JOURNAL OF THE STOMATOLOGICAL SOCIETY,JAPAN 65, no. 1 (1998): 42–52. http://dx.doi.org/10.5357/koubyou.65.42.
Повний текст джерелаHattori, Kazuki, and Hidenori Ichijo. "Apoptosis signal-regulating kinase 1 in regulated necrosis." Cell Cycle 17, no. 1 (January 2, 2018): 5–6. http://dx.doi.org/10.1080/15384101.2017.1397330.
Повний текст джерелаWeijman, Johannes F., Abhishek Kumar, Sam A. Jamieson, Chontelle M. King, Tom T. Caradoc-Davies, Elizabeth C. Ledgerwood, James M. Murphy, and Peter D. Mace. "Structural basis of autoregulatory scaffolding by apoptosis signal-regulating kinase 1." Proceedings of the National Academy of Sciences 114, no. 11 (February 27, 2017): E2096—E2105. http://dx.doi.org/10.1073/pnas.1620813114.
Повний текст джерелаNishida, Kazuhiko, and Kinya Otsu. "The Role of Apoptosis Signal-Regulating Kinase 1 in Cardiomyocyte Apoptosis." Antioxidants & Redox Signaling 8, no. 9-10 (September 2006): 1729–36. http://dx.doi.org/10.1089/ars.2006.8.1729.
Повний текст джерелаFujisawa, Takao. "Therapeutic application of apoptosis signal-regulating kinase 1 inhibitors." Advances in Biological Regulation 66 (December 2017): 85–90. http://dx.doi.org/10.1016/j.jbior.2017.10.004.
Повний текст джерелаKawarazaki, Yosuke, Hidenori Ichijo, and Isao Naguro. "Apoptosis signal-regulating kinase 1 as a therapeutic target." Expert Opinion on Therapeutic Targets 18, no. 6 (March 24, 2014): 651–64. http://dx.doi.org/10.1517/14728222.2014.896903.
Повний текст джерелаMizuguchi, Junichiro, Eiko Takada, and Masae Furuhata. "Apoptosis signal-regulating kinase (ASK)-1 mediates apoptosis in B cells (34.6)." Journal of Immunology 182, no. 1_Supplement (April 1, 2009): 34.6. http://dx.doi.org/10.4049/jimmunol.182.supp.34.6.
Повний текст джерелаZou, Xianghong, Tateki Tsutsui, Dipankar Ray, James F. Blomquist, Hidenori Ichijo, David S. Ucker, and Hiroaki Kiyokawa. "The Cell Cycle-Regulatory CDC25A Phosphatase Inhibits Apoptosis Signal-Regulating Kinase 1." Molecular and Cellular Biology 21, no. 14 (July 15, 2001): 4818–28. http://dx.doi.org/10.1128/mcb.21.14.4818-4828.2001.
Повний текст джерелаДисертації з теми "Apoptosis signal-regulating kinase 1"
Chibon, Frédéric. "Étude des altérations génétiques des sarcomes indifférenciés : mise en relation des anomalies identifiées et de la différenciation tumorale." Paris 7, 2002. http://www.theses.fr/2002PA077050.
Повний текст джерелаPillai, Prajit P. "Role of Protein Kinase C-iota in Neuroblastoma and the Effect of ICA-1, a Novel Protein Kinase C-iota Inhibitor on the Proliferation and Apoptosis of Neuroblastoma Cells." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3292.
Повний текст джерелаPoser, Steven Walter. "Coincident signaling of cAMP with phosphatidylinositol 3' kinase and mitogen activated protein kinase signal transduction cascades : a role in regulating gene exression during development and synaptic plasticity /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/10633.
Повний текст джерелаLi, Li-Fu, and 李立夫. "Apoptosis Signal-Regulated Kinase 1 and c-Jun N-terminal Kinase Regulated Ventilation-Induced Inflammatory Cytokine and Lung Apoptosis." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/98554179740295415443.
Повний текст джерела長庚大學
臨床醫學研究所
93
Positive pressure ventilation with large tidal volumes has been shown to cause release of cytokines, including macrophage inflammatory protein-2 (MIP-2), a functional equivalent of human Interleukin (IL)-8. The mechanisms regulating ventilation-induced cytokine production are unclear. We designed three experiments to explore the mechanisms underlying ventilator-induced lung injury. We hypothesized that high tidal volume ventilation-induced IL-8 or MIP-2 production and lung apoptosis are dependent on the activation of apoptosis signal-regulated kinase 1 (ASK1) and c-Jun N-terminal kinase (JNK). We exposed A549 cells, a type II-like alveolar epithelial cell line, to cyclic stretch at 20 cycles/minute for 5 minutes to two hours and C57BL/6 mice to high tidal volume (30 ml/kg) or low tidal volume (6 ml/kg) mechanical ventilation for 5 hours. Cyclic stretch induced IL-8 protein production, IL-8 mRNA expression and JNK activation, but only transient activation of p38 and ERK1/2. High tidal volume ventilation induced neutrophil migration into the lung, airway epithelial apoptosis, MIP-2 protein production, MIP-2 mRNA expression, and activation of ASK1, JNK, and activator protein-1 (AP-1) DNA binding. Inhibition of stretch-induced JNK activation by adenovirus- mediated gene transfer of SEK-1 (KR), a dominant inhibitory mutant of SEK-1, the immediate upstream activator of the JNKs, and pharmacological JNK inhibitor II SP600125, blocked IL-8 mRNA expression and attenuated IL-8 production. Inhibition of p38 and ERK1/2 did not affect stretch-induced IL-8 production. Stretch-induced activation nuclear factor (NF)-kB and AP-1 was blocked by NF-kB inhibitor and JNK inhibitor, respectively. NF-IL-6 site was not essential for cyclic stretch-induced IL-8 promoter activity. Stretch also induced NF-kB-inducing kinase (NIK) activation, and inhibition of NF-kB attenuated IL-8 mRNA expression and IL-8 production. Large tidal volume ventilation of JNK knockout mice, and pharmacological JNK inhibition with SP600125 and ASK1 inhibition with thioredoxin attenuated neutrophil sequestration, and blocked MIP-2 mRNA expression, MIP-2 production, airway epithelial cell apoptosis, activation of JNK and AP-1 DNA binding. We conclude that lung cell stretch in vitro and in vivo, results in increased neutrophil sequestration, apoptotic cell death, and increased IL-8 or MIP-2 production, which were, at least in part, dependent, on the ASK1/JNK pathway.
Chang, Chia-Kai, and 張家凱. "The Role of Apoptosis Signal Regulated Kinase 1 in Peptidoglycan-Induced Cyclooxygenase-2 Expression in RAW 264.7 Macrophages." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/50372115705052938243.
Повний текст джерела臺北醫學大學
藥理學研究所
93
Abstract The Ras/Raf-1/extracellular signal-regulated kinase (ERK) pathway is known to be involved in peptidoglycan (PGN)-induced nuclear factor-B (NF-B) activation and cyclooxygenase-2 (COX-2) expression in RAW 264.7 macrophages (J. Biol. Chem. 2004, 297: 20889-20897). In this study, we further investigated the roles of apoptosis signal regulated kinase 1 (ASK1), c-jun N-terminal kinase (JNK), activator protein-1 (AP-1), and CCAAT/enhancer binding protein (C/EBP) in PGN-induced COX-2 expression. The PGN-induced COX-2 expression was attenuated by the ASK1 dominant negative mutant (ASK1DN), a JNK inhibitor (SP600125), the JNK1 dominant negative mutant (JNK1DN), the JNK2DN, and the AP-1 inhibitor (curcumin). PGN induced the recruitment of TNFR-associated factor 6 (TRAF6) and ASK1 to toll-like receptor 2 (TLR2) in a time-dependent manner. Treatment of RAW 264.7 macrophages with PGN caused time-dependent dissociation of 14-3-3 with ASK1 and dephosphorylation of ASK1 which resulted in activations of ASK1 and further activates JNK and c-jun. The PGN-induced JNK activation was inhibited by ASK1DN and SP600125. Stimulation of cells with PGN activated the formation of AP-1 specific-DNA protein complex and AP-1-luciferase activity. The PGN-mediated increase in AP-1-luciferase activity was inhibited by SP600125, and curcumin. Treatment of macrophages with PGN caused time-dependent C/EBP expression. Stimulation of cells with PGN caused the formation of C/EBP-specific DNA-protein complex. Furthermore, PGN-induced increase in COX-2-luciferase activity was inhibited by cells transfected with the C/EBP site mutation of COX-2-construct. Our data demonstrated that PGN induced the recruitment of TRAF6 to TLR2 to activate the ASK1/JNK/AP-1 pathway, which in turn initiates CEBP expression and activation, and ultimately induces COX-2 expression in RAW 264.7 macrophages.
Ling, Ling. "Investigarion of Activated Phosphaidylinositol 3’ Kinase Signaling in Stem Cell Self-renewal and Tumorigenesis." Thesis, 2012. http://hdl.handle.net/1807/32815.
Повний текст джерелаBusch, F., A. Mobasheri, P. Shayan, C. Lueders, R. Stahlmann, and M. Shakibaei. "Resveratrol modulates interleukin-1beta-induced phosphatidylinositol 3-kinase and nuclear factor kappaB signaling pathways in human tenocytes." 2012. http://hdl.handle.net/10454/5903.
Повний текст джерелаMok, Sue-Ann. "Retrograde signaling mechanisms of nerve growth factor regulating the survival and apoptosis of sympathetic neurons." Phd thesis, 2009. http://hdl.handle.net/10048/447.
Повний текст джерелаЧастини книг з теми "Apoptosis signal-regulating kinase 1"
Zimmermann, Arthur. "Etiology and Pathogenesis of Hepatocellular Carcinoma: Transcription Factors, Signal Pathways Regulating Proliferation and Apoptosis, and Telomeres/Telomerases." In Tumors and Tumor-Like Lesions of the Hepatobiliary Tract, 1–22. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26587-2_167-1.
Повний текст джерела"ASK1 (apoptosis signal regulating kinase)." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics, 149. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_1223.
Повний текст джерелаKatagiri, Kazumi, Atsushi Matsuzawa, and Hidenori Ichijo. "Regulation of Apoptosis Signal-Regulating Kinase 1 in Redox Signaling." In Methods in Enzymology, 277–88. Elsevier, 2010. http://dx.doi.org/10.1016/s0076-6879(10)74016-7.
Повний текст джерелаZou, Jin, Wei Shen, Yu Zhang, and Shibo Ying. "The Role of Protein Arginine Methyltransferase 1 in Gastrointestinal Cancers." In Post-Translational Modifications in Cellular Functions and Diseases. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96197.
Повний текст джерелаEvans Adunyah, Samuel, Richard Akomeah, Fareed K.N. Arthur, Roland S. Cooper, and Joshua C.M. Williams. "IL-17 Biological Effects and Signaling Mechanisms in Human Leukemia U937 Cells." In Interleukins - The Immune and Non-Immune Systems’ Related Cytokines. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96422.
Повний текст джерелаТези доповідей конференцій з теми "Apoptosis signal-regulating kinase 1"
Tang, Xiaofei, Jian-Fei Zhang, Wen-wen Niu, and Min Zhang. "Abstract 2280: Role of apoptosis signal-regulating kinase 1 in the cell apoptosis in oral leukoplakia." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2280.
Повний текст джерелаImmanuel, C. N., B. Teng, B. Dong, J. Tatum, E. Gordon, C. Luellen, A. Schwingshackl, E. A. Fitzpatrick, S. Cormier, and C. M. Waters. "Apoptosis Signal Regulating Kinase-1 (ASK1) Differentially Activates p38- and JNK-Mediated Inflammasome Pathways." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2092.
Повний текст джерелаMakena, Patrudu S., Manik C. Ghosh, Vijay K. Gorantla, Lavanya Bezawada, Louisa Balazs, Charlean L. Luellen, Hidenori Ichijo, Christopher M. Waters, and Scott E. Sinclair. "Regulation Of ERK-1,2 By Apoptosis Signal Regulating Kinase-1 (ASK-1) Is Required For Ventilator Induced-Apoptosis And Lung Injury." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5435.
Повний текст джерелаOkamoto, Shinichi, Shuichiro Maruoka, Kota Tsuya, Yasuhiro Gon, Kenji Mizumura, Shu Hashimoto, Kaori Soda, Isao Naguro, and Hidenori Ichijo. "Involvement of apoptosis signal-regulating kinase-1 in house dust mite-induced allergic asthma in mice." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa576.
Повний текст джерелаMakena, Patrudu S., Vijay K. Gorantla, Manik C. Ghosh, Lavanya Bezawada, Louisa Balazs, Charlean L. Luellen, Hidenori Ichijo, Scott E. Sinclair, and Christopher M. Waters. "Apoptosis Signal Regulating Kinase 1 Negatively Regulates Survivin Via P38/MAPK And Egr1 In Ventilator Induced Apoptosis And Lung Injury." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5438.
Повний текст джерелаMakena, Patrudu S., Vijay K. Gorantla, Charlean Luellen, Christopher M. Waters, and Scott E. Sinclair. "Apoptosis Signal Regulating Kinase-1 (ASK-1) Deficiency Protects From Apoptosis And Autophagy Induced By Combined High Tidal Volume Mechanical Ventilation And Hyperoxia." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a1673.
Повний текст джерелаBoehm, Mario, Baktybek Kojonazarov, Hossein Ardeschir Ghofrani, Friedrich Grimminger, Norbert Weissmann, John T. Liles, Grant R. Budas, Werner Seeger, and Ralph T. Schermuly. "Effects of apoptosis signal- regulating kinase 1 (ASK1) inhibition in experimental pressure overload-induced right ventricular dysfunction." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa4913.
Повний текст джерелаHayakawa, Yoku, Yoshihiro Hirata, Hayato Nakagawa, Kei Sakamoto, Wachiko Nakata, Hiroto Kinoshita, Ryota Takahashi, et al. "Abstract 3133: Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3133.
Повний текст джерелаMakena, Patrudu S., Manik C. Ghosh, Vijay K. Gorantla, Lavanya Bezawada, Charlean L. Luellen, Christopher M. Waters, and Scott E. Sinclair. "Apoptosis Signal-Regulating Kinase-1 (ASK-1) Knockdown Augments Antioxidant Response Element (ARE)-Mediated Gene Expression Of Phase-II Antioxidant Enzymes (AOES) During Acute Hyperoxia (HO) Exposure." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5971.
Повний текст джерелаWang, Xuening, Jonathan S. Harrison, and George P. Studzinski. "Abstract 315: Cell death of AML blasts induced by cytarabine and enhanced by the Vitamin D2/Carnosic acid cell differentiating combination involves apoptosis signal-regulating kinase 1 (ASK1) activation." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-315.
Повний текст джерелаЗвіти організацій з теми "Apoptosis signal-regulating kinase 1"
Chamovitz, Daniel A., and Xing-Wang Deng. Developmental Regulation and Light Signal Transduction in Plants: The Fus5 Subunit of the Cop9 Signalosome. United States Department of Agriculture, September 2003. http://dx.doi.org/10.32747/2003.7586531.bard.
Повний текст джерелаChamovitz, Daniel, and Albrecht Von Arnim. Translational regulation and light signal transduction in plants: the link between eIF3 and the COP9 signalosome. United States Department of Agriculture, November 2006. http://dx.doi.org/10.32747/2006.7696515.bard.
Повний текст джерелаBarash, Itamar, and Robert Rhoads. Translational Mechanisms Governing Milk Protein Levels and Composition. United States Department of Agriculture, 2006. http://dx.doi.org/10.32747/2006.7696526.bard.
Повний текст джерела