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Автор: Grafiati
Опубліковано: 22 червня 2024

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1

Curtis, Christina. "Abstract ED7-4: Beyond the lab: Clinical implications." Cancer Research 83, no. 5_Supplement (March 1, 2023): ED7–4—ED7–4. http://dx.doi.org/10.1158/1538-7445.sabcs22-ed7-4.

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Abstract During this talk, I will review the ever expanding repertoire of single cell and spatially resolved profiling techniques which enable the interrogation breast cancer pathlogy, immuno-biology and treatment response at unprecedented resolution. I will outline considerations for throughput, plex and resolution across different methods before providing several case studies in their application. As one example, I will outline the use of multi-omic single cell profiling and spatial proteomic profiling to characterize changes throughout the course of neoadjuvant Her2-targeted therapy and leading to the identification of candidate predictive biomarkers. I will go on to discuss translational and potential clinical applications of these techniques. Citation Format: Christina Curtis. Beyond the lab: Clinical implications [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr ED7-4.
2

Poole, Gordon. "Totò’s talking body." Gesture 7, no. 2 (June 19, 2007): 241–53. http://dx.doi.org/10.1075/gest.7.2.06poo.

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The full-bodied, multi-faceted use of gesture by Italy’s beloved vaudeville and cinema comedian Antonio De Curtis, in art Totò, is rooted in the rich gesture language of Naples. Totò’s humble origins, the experience of poverty and deprivation, conditioned his art, as did his immersion as a mere child into the rough-and-tumble world of Neapolitan street theater. The teeming neighborhoods of Naples, a Baroque city, have made it into somewhat of a theatrum mundi, producing many fine actors and playwrights. The essay, illustrated by photograms from a few of Totò’s films, suggests that Neapolitan gesture, whose purpose is communication, is stylized by Totò and transformed into artistry of a high order.
3

Merino Gómez, Elena, Fernando Moral Andrés, and Alexandra Delgado Jiménez. "conversando con...RCR arquitectes. Parte I: De los límites del dibujo. Nostalgia de la ingravidez." EGA Revista de expresión gráfica arquitectónica 23, no. 34 (November 27, 2018): 24. http://dx.doi.org/10.4995/ega.2018.10934.

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<p>RCR arquitectes comparten sistemas de representación con otras oficinas de igual entidad. La homogenización que la digitalización tiende a imponer nos conduce a localizar un importante repertorio de representaciones gráficas similares a lo largo y ancho de Occidente. Toda la normativa que condiciona el conjunto de los proyectos que salen de los despachos también acentúa esta lectura uniforme. En cualquier caso es posible localizar alteraciones específicas de cada despacho que nos presentan realidades diferentes y enriquecedoras para el panorama gráfico arquitectónico. Probablemente en estas anomalías es donde se revela el espíritu más singular que anida en cada oficina, también en la de Rafael, Carme y Ramón.</p><p>No existe una gran literatura que ayude a descifrar la importancia, capital, que tienen sus dibujos en el conjunto de su trayectoria. Indudablemente, sus aguadas configuran el torrente necesario del que se nutren sus obras. Es una técnica que ha caracterizado su identidad como estudio a lo largo de estos años de trabajo. Como apuntan, es un instrumento con un recorrido casi automático entre el pensamiento y el brazo. Un camino ágil que les conduce a presentar sus ideas de forma vigorosa y abstracta. Esas manchas de agua tintada permiten una lejanía prudencial con respecto a la forma última que adoptará la propuesta y facilitan el debate conceptual, la esencia genuina de sus aportaciones. Esos dibujos, de diferentes formatos, pueden ser más o menos precisos (o difusos) contaminados, generalmente, con trazos y apuntes de gruesa lapicera que buscan fijar matices y preceptos que articulan el proyecto venidero. Este material trasluce el compromiso máximo entre los arquitectos y su trabajo. RCR no opera desde una inercia superficial, todas sus obras concentran una rica cantidad de variantes que certifican ese extenuante trabajo intelectual. William J. R. Curtis apunta que sus creaciones, gráficas y constructivas, se desarrollan durante un proceso largo pero armonioso, evidencia esa ligación, necesaria, que existe entre ambas facetas de su quehacer profesional (Curtis, 2017, p.6).</p><p>En 2007 el catedrático Juan Antonio Cortés evidenciaba, bajo el epígrafe de “Naturaleza, pintura, arquitectura” ciertas reflexiones que ligaban a la arquitectura de RCR con cuestiones rítmicas trabajadas por el pintor Pierre Soulages y también con la aseveración de la existencia de un estilo propio de la oficina cimentado a través de diferentes variaciones ancladas a una concepción específica (personal) del hecho arquitectónico (Cortés, 2007, p.22). Sus dibujos son claves para llegar a comprender esta realidad intelectual, singular como pocas, y en continua búsqueda de esencias que sustancien nuevas intervenciones nacidas desde un trazo grueso. En este punto se hace necesario señalar cómo la arquitectura de su oficina es un referente internacional de primera magnitud pero el camino que apuntan sus dibujos, en sí mismos, nos hace atisbar una “vis artística” de poderosa constitución. Sin duda alguna, el futuro confirmará esta eclosión pictórica dentro del universo creativo de RCR.</p>
4

Houlahan, Kathleen, Aziz Khan, Noah Greenwald, Robert West, Michael Angelo, and Christina Curtis. "Abstract GS03-11: Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity." Cancer Research 84, no. 9_Supplement (May 2, 2024): GS03–11—GS03–11. http://dx.doi.org/10.1158/1538-7445.sabcs23-gs03-11.

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Abstract Background: Somatic genomic aberrations are acquired within the context of germline genomes which differ across individuals at millions of polymorphic sites. However, the role of germline variation in somatic evolution remains poorly understood. The most compelling example is is that deleterious germline variants in BRCA1 and, to a lesser extent, BRCA2 are preferentially associated with the development of triple-negative breast cancer (BC). The variable frequency of BC subtypes across ancestral populations further suggests a role for germline contributions. On the other hand, various lines of evidence indicate that avoidance of the adaptive immune system is a strong determinant of which somatic mutations persist within a tumor. Whether and how germline differences influence immunoediting has not been studied. Building on these observations, we sought to investigate whether germline variation mediates somatic evolution through immunoediting. Specifically, we hypothesize inherited variation in oncogenes would be subject to varied immunoediting pressures during malignant transformation and progression. A high burden of germline-derived epitopes in recurrently amplified oncogenes is predicted to select against amplification of the cognate gene during malignant transformation because this would increase epitope availability, the likelihood of epitope presentation, and immune-mediated cell death. Instead, immune pressures may select for amplification of an alternate driver gene with a lower germline-mediated epitope burden. We evaluated this hypothesis in a collection of 3,855 BC, spanning ductal carcinoma in situ (DCIS) to invasive BC, and metastatic lesions. Methods: We analyzed paired tumor and normal sequencing data from 1,087 primary and 702 metastatic breast cancer patients as well as somatic genomic profiles from 341 patients with DCIS using a novel algorithm to estimate germline-derived epitope burden (GEB) based on an individual’s genotype and class 1 HLA alleles. The relationship between GEB and subtype commitment, defined by the acquisition of focal oncogenic amplifications in five prognostic subgroups of BC: HER2+ disease and four high-risk of relapse ER+/HER2 integrative subgroups/clusters (ICs) which we previously described (IC1: 17q23, IC2: 11q13, IC6: 8p12, and IC9: 8q24) was evaluated. Specifically, we evaluated the association between the GEB per gene and whether an individual developed the corresponding subtype via logistic regression, correcting for the first six genetic principal components and somatic mutation burden. Outcome associations were evaluated via Cox Proportional Hazards Models. Results: Interrogating 3,855 breast cancer lesions, we demonstrate that germline-derived epitopes in recurrently amplified genes influence somatic evolution by mediating immunoediting. Individuals with a high GEB in ERBB2/HER2 are significantly less likely to develop HER2-positive breast cancer compared to other subtypes. The same holds true for recurrent amplicons that define four aggressive, high-risk of relapse, ER-positive integrative subgroups. Thus, GEB selects against cognate oncogene amplification. Tumors that overcome such immune-mediated negative selection are more aggressive and exhibited microenvironments depleted of lymphocytes, consistent with “immune cold” tumors. Conclusions: We demonstrate that inherited variation sculpts breast cancer subtypes, aggressivity, and immune landscapes by mediating anti-tumor immune responses. The implications of these findings are severalfold. First, GEB is prognostic, complementing other molecular measurements. Second, immunoediting pressures differ across the disease course, with implications for the timing of therapeutic interventions. Third, these data illuminate a broad source of currently under-appreciated immunogenic antigens. Citation Format: Kathleen Houlahan, Aziz Khan, Noah Greenwald, Robert West, Michael Angelo, Christina Curtis. Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr GS03-11.
5

Cole, Kimberly, Melissa Tjota, Jeremy Segal, Peng Wang, and Susanne Crespo-Ramos. "Abstract PO5-24-06: Genomic findings in metastatic breast cancer." Cancer Research 84, no. 9_Supplement (May 2, 2024): PO5–24–06—PO5–24–06. http://dx.doi.org/10.1158/1538-7445.sabcs23-po5-24-06.

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Abstract Introduction: Although metastatic breast cancer is the second leading cause of cancer death in women, the genomic findings in metastatic breast cancer are not as well characterized as those of primary breast cancers. Metastatic tumors are genetically heterogenous, enriched for resistance mutations, and often lack targetable alterations. Improved understanding of the molecular mechanisms that drive metastatic disease of all receptor subtypes is required to identify possible molecular targets and to develop new targeted therapies in an effort to reduce the mortality. Methods: A cohort of 50 metastatic breast cancer cases (n=33 ER+/PR+, n=3 ER+/HER2+, n=3 ER-/HER2+ n=11 TNBC) sequenced at our medical center between 2018-2023 was evaluated, and the molecular findings of the major subtypes were analyzed. Genomic data included mutations, copy number alterations, tumor mutation burden and microsatellite instability. Results: The most frequent somatic alteration were PIK3CA mutations, involving 17/33 of ER+/PR+/HER- tumors, 5/11 TNBC tumors and 5/6 HER+ cases. TP53 mutations (frameshift and missense) were more frequently identified in TNBC and HER2+ cases (p&lt; 0.05). Recurrent CCND1, FGFR1 and MYC copy number amplifications were seen almost exclusively in hormone receptor positive/HER2- tumors (p &gt;0.05). ESR1 mutations involved 15% of the ER positive cancers and were frequently associated with co-occurring CCND1 and FGFR1 copy number gains. Significant genomic losses that drive tumorigenesis were also detected. Both CDKN2a and PTEN deletions were found in ER/PR positive disease, as well as triple negative tumors. Genomic deletions associated with worse outcomes such as TP53 and DICER1 were also detected. ERBB2 amplification was 100% concordant with our immunohistochemical and FISH results for the 6 HER2 positive cases. All 50 cases demonstrated a low tumor mutation burden and were microsatellite stable. Conclusion: We detected driver alterations that involve multiple pathways including estrogen receptor signaling, PI3K/AKT/MTOR, the cell cycle, and receptor tyrosine kinases. The genomic alterations are enriched for resistance mechanisms, like ESR1 mutations and FGFR1 gains that mediate resistance to endocrine treatment, as well as PIK3CA, also implicated in both endocrine and HER2-targeting therapy resistance. Of particular interest, were the amplifications detected in the ER+/PR+ tumors, such as CCND1 on chromosome 11q, FGFR1 on 8p and MYC on 8q, which were detected in almost half (45%) of our hormone receptor positive cohort. Some of the identified driver amplifications also define a subset of the Integrated Molecular Subtypes (Curtis et al., Nature; 486(7403): 346–352), i.e., Clusters 2, 6 and 9 that are typically hormone receptor positive but associated with either a very poor prognosis (Cluster 2) or an intermediate prognosis (Clusters 6 and 9), unlike the copy neutral ER positive tumors or those with the classic 1p and 16q alterations. Therefore, copy number profiling of advanced-stage breast cancers may be a useful tool for determining prognosis, identifying possible targetable driver pathways and selecting appropriate patients for molecularly guided clinical trials. Citation Format: Kimberly Cole, Melissa Tjota, Jeremy Segal, Peng Wang, Susanne Crespo-Ramos. Genomic findings in metastatic breast cancer [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO5-24-06.
6

Strand, Siri H., Belén Rivero-Gutiérrez, Kathleen E. Houlahan, Jose A. Seoane, Lorraine M. King, Tyler Risom, Lunden Simpson, et al. "Abstract GS4-07: The Breast PreCancer Atlas DCIS genomic signatures define biology and correlate with clinical outcomes: An analysis of TBCRC 038 and RAHBT cohorts." Cancer Research 82, no. 4_Supplement (February 15, 2022): GS4–07—GS4–07. http://dx.doi.org/10.1158/1538-7445.sabcs21-gs4-07.

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Abstract Background. DCIS consists of a molecularly heterogeneous group of premalignant lesions, with variable risk of invasive progression. Understanding biomarkers for invasive progression could help individualize treatment recommendations based upon tumor biology. As part of the NCI Human Tumor Atlas Network (HTAN), we conducted comprehensive genomic analyses on two large DCIS case-control cohorts. Methods. We performed smart3-seq and low-pass whole genome sequencing on two independent, retrospective, longitudinally sampled DCIS case-control cohorts. TBCRC 038 was a multicenter cohort diagnosed with DCIS between 1998 and 2016 at one of the Translational Breast Cancer Research sites; the RAHBT (Resource of Archival Human Breast Tissue) cohort included women identified through the St. Louis Breast Tissue Repository, and the Women’s Health Repository diagnosed between 1997 and 2001. We studied the spectrum of molecular changes present and sought genomic predictors of subsequent ipsilateral breast events (iBEs: DCIS recurrence or invasive progression) in both DCIS epithelium and stroma in formalin fixed paraffin embedded tissue. We generated de novo tumor and stroma-centric subtypes for DCIS that represents fundamental transcriptomic organization. Copy number analysis was performed using low-pass DNA sequencing. Non-negative matrix factorization (NMF) was applied to the RNA expression of all coding genes to identify clusters. A negative-binomial regression model was used to identify differentially expressed genes. Results. We analyzed 677 DCIS samples from 481 patients with 7.1 years median follow-up. In TBCRC samples, we identified three clusters via NMF in TBCRC referred to as ER low, quiescent, and ER high. The ER-low cluster had significantly higher levels of ERBB2 and lower levels of ESR1 compared to quiescent and ER-high clusters. Quiescent cluster lesions were less proliferative and less metabolically active than ER high and ER low subtypes. These findings were replicated in the RAHBT cohort. Focusing on the stromal component of DCIS from laser capture microdissection in RAHBT samples, we identified four distinct DCIS-associated stromal clusters. A “normal-like” stromal cluster with ECM organization and PI3K-AKT signaling; a “collagen-rich” stromal cluster; a “desmoplastic” stromal cluster with high fibroblast and total myeloid abundance, mostly associated with macrophages and myeloid dendritic cells (mDC); and an “immune-dense” stromal cluster. Further, we compared differentially expressed genes in patients with or without subsequent iBEs within 5 years of diagnosis. Hypothesizing that the resulting 812 DE genes (DESeq2) represent multiple routes to subsequent iBEs, we leveraged NMF to identify paths to progression. In both TBCRC and RAHBT cohorts, poor outcome groups exhibited increased ER, MYC signaling, and oxidative phosphorylation, supporting that these pathways are important for DCIS recurrence and progression. Conclusion. Comprehensive genomic profiling in two independent DCIS cohorts with longitudinal outcomes shows distinct DCIS stromal expression patterns and immune cell composition. RNA expression profiles reveal underlying tumor biology that is associated with later iBEs in both cohorts. These studies provide new insight into DCIS biology and will guide the design of diagnostic strategies to prevent invasive progression. Citation Format: Siri H Strand, Belén Rivero-Gutiérrez, Kathleen E Houlahan, Jose A Seoane, Lorraine M King, Tyler Risom, Lunden Simpson, Sujay Vennam, Aziz Khan, Timothy Hardman, Bryan E Harmon, Fergus J Couch, Kristalyn Gallagher, Mark Kilgore, Shi Wei, Angela DeMichele, Tari King, Priscilla F McAuliffe, Julie Nangia, Joanna Lee, Jennifer Tseng, Anna Maria Storniolo, Alastair Thompson, Gaorav Gupta, Robyn Burns, Deborah J Veis, Katherine DeSchryver, Chunfang Zhu, Magdalena Matusiak, Jason Wang, Shirley X Zhu, Jen Tappenden, Daisy Yi Ding, Dadong Zhang, Jingqin Luo, Shu Jiang, Sushama Varma, Cody Straub, Sucheta Srivastava, Christina Curtis, Rob Tibshirani, Robert Michael Angelo, Allison Hall, Kouros Owzar, Kornelia Polyak, Carlo Maley, Jeffrey R Marks, Graham A Colditz, E Shelley Hwang, Robert B West. The Breast PreCancer Atlas DCIS genomic signatures define biology and correlate with clinical outcomes: An analysis of TBCRC 038 and RAHBT cohorts [abstract]. In: Proceedings of the 2021 San Antonio Breast Cancer Symposium; 2021 Dec 7-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2022;82(4 Suppl):Abstract nr GS4-07.
7

Mattick, Lindsey, Hongying Sun, Karen Mustian, Luke Peppone, AnnaLynn Williams, Po-Ju Lin, Evelyn Arana, et al. "Abstract PO4-12-09: National Physical Activity Guidelines and It’s Association with Fatigue in Patients with Breast Cancer Pre- and Post-Chemotherapy in a Prospective, Nationwide Study." Cancer Research 84, no. 9_Supplement (May 2, 2024): PO4–12–09—PO4–12–09. http://dx.doi.org/10.1158/1538-7445.sabcs23-po4-12-09.

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Abstract Background: Cancer-related fatigue (CRF) is one of the most pervasive side effects of cancer and its treatment, reported by nearly 90% of patients. Physical activity (PA) during treatment may prevent or lessen CRF burden. Current aerobic PA guidelines for cancer patients recommend at least 150 minutes of moderate PA or 75 minutes of vigorous PA or some equivalent combination of moderate and vigorous PA (MVPA). Many patients have difficulty meeting these guidelines during treatment, however, meeting these guidelines may not be necessary to alleviate CRF. This study evaluated patterns of PA below the recommended guidelines and their association with CRF in cancer patients during treatment. Methods: In a nationwide, prospective cohort study of patients with stage I-IIIC breast cancer (n=580) we assessed the relationship between self-reported PA (Aerobics Center Longitudinal Study PA) and CRF (Multidimensional Fatigue Symptom Inventory, MFSI) pre- and post-chemotherapy. Spearman correlations were utilized to evaluate the association of all PA (MET hr/wk) and MVPA (MET hr/wk) with overall CRF (total MFSI) and 5 CRF subdimensions (general, physical, emotional, mental CRF and vigor) at pre- and post-chemotherapy. ANCOVA estimated mean CRF score according to whether patients weekly MVPA (1) met 100% of the PA guidelines, (2) met 50%-99% of the PA guidelines (75-149 minutes), or (3) did not meet 50% of the PA guidelines (&lt; 75 minutes). Results: Pre-chemotherapy, only 34% of participants met the PA guidelines, post-chemotherapy, only 21% of patients met the PA guidelines. At both time points, we observed small to moderate inverse correlations of MVPA with overall CRF and several subdimensions of CRF (Table 1; r = -0.11, -0.19). Pre-chemotherapy, those who did not meet 50% of the PA guidelines report significantly higher total CRF compared to those who met the PA guidelines (12.5 ± 1.2 vs 5.3 ± 1.5; p&lt; 0.001). However, those who met only 50%-99% of the PA guidelines, had comparable total CRF to those who fully met the PA guidelines (7.2 ± 2.2; p=0.474). A similar pattern was observed for the subdimensions general, mental, and physical CRF. Those who met 50% of the guidelines also had significantly lower vigor compared to those who met the guidelines (11.9 ± 0.3 vs 13.8 ± 0.4; p&lt; 0.001), while those who met 50%-99% of the guidelines had comparable vigor to those who fully met guidelines (13.1 ± 0.6; p=0.278). Post-chemotherapy CRF was higher among all patient’s, again there was no significant difference in total, general, physical CRF and vigor between those who met the PA guidelines and those who met 50%-99% of the PA guidelines. Conclusions: All PA was consistently inversely associated with CRF pre- and post-chemotherapy for patients with breast cancer. Current minimum aerobic PA guidelines for patients with cancer are difficult to achieve during treatment. Lower doses of MVPA than the current PA guidelines suggest may provide equal benefit and represent a more achievable goal for patients with cancer. Table 1: Spearman correlations of CRF and physical activity in patients with breast cancer pre- and post-chemotherapy. Table 2: ANCOVA; Mean CRF score according to the PA guidelines. Citation Format: Lindsey Mattick, Hongying Sun, Karen Mustian, Luke Peppone, AnnaLynn Williams, Po-Ju Lin, Evelyn Arana, Jeremy McGuire, Amarinthia Curtis, Alison Conlin, Lora Weiselberg, Michelle Janelsins. National Physical Activity Guidelines and It’s Association with Fatigue in Patients with Breast Cancer Pre- and Post-Chemotherapy in a Prospective, Nationwide Study [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO4-12-09.
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Pisano, Etta, Constantine Gatsonis, Mitchell Schnall, Melissa Troester, Elodia Cole, Jean Cormack, Ilana Gareen, et al. "Abstract PO3-19-03: Addressing USPSTF 2023 Identified Key Gaps in Knowledge in Breast Cancer Screening through TMIST (ECOG-ACRIN EA1151) or its Ancillary Studies." Cancer Research 84, no. 9_Supplement (May 2, 2024): PO3–19–03—PO3–19–03. http://dx.doi.org/10.1158/1538-7445.sabcs23-po3-19-03.

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Abstract Background The United States Preventative Services Task Force in their 2023 recommendations identified areas where more research data is needed to inform future breast cancer screening recommendations. Research areas identified are: improve clinicians and patients understanding and evaluation of dense breast tissue on a screening mammogram, benefits and harms of supplemental screening using ultrasound or MRI for women with dense breasts, health outcomes such as rates of breast cancer diagnosis requiring treatment, rates of advanced breast cancers diagnosed across consecutive screening rounds, and breast cancer-associated morbidity and mortality, causes of increased risk of breast cancer mortality in black women across spectrum of stages and biomarker patterns, understand why black women are more likely to be diagnosed with breast cancers that have biomarker patterns that are indicative of poor health outcomes, assess benefits/harms differences between annual and biennial screening for breast cancer in women overall and if there are differences between black and white women, approaches to reduce the risk of overdiagnosis leading to overtreatment of breast lesions found at screening that may not cause morbidity and mortality, natural history of DCIS, and identify prognostic indicators of breast tumors that are unlikely to affect quality or length of life. Methods The ongoing TMIST study, currently with 88,801 asymptomatic women presenting for screening mammography ages 45-74 enrolled out of 128,905, could contribute to scientific evidence to support the above research areas through existing study aims and planned ancillary studies. Supplemental Screening with US and MRI: TMIST PreSCRIB will utilize Machine Learning applied to TMIST and All of Us data, including genetics, mammograms, social determinates of health and other data to recommend individualized screening strategies for women. DxMRI is a study where women will get AbMRI at time of Dx work-up. There are plans to use these examinations plus supplemental screening MRIs performed on TMIST subjects in an enriched reader study to evaluate the role of supplemental screening MRI in moderate risk women. Rates of breast cancer treatment, consecutive screening, morbidity, and mortality: TMIST’s primary outcome is the proportion of women experiencing an advanced breast cancer and needing treatment. TMIST is also collecting information on health care utilization following a cancer diagnosis, including types of treatment given, and costs data from the screening and diagnostic work-up visits, and mortality data for study participants. Increased risk of breast cancer mortality in black women: TMIST is performing PAM50 plus p53 status, immune profile, DNA repair phenotype, and 21-gene recurrence assay on all breast cancers and a subset of benign tissue. Blood and buccal smears might also help address this issue. Ongoing work, funded by the Susan B. Komen Foundation, focuses on improving Black participation in TMIST Biorepository (currently about 45% participation of the 21% of TMIST US black subjects). Surveys are planned on perceived racism and social determinates of health as part of DxMRI Study. Screening Frequency: We are developing a collaboration with the UK-based clinical trial PROSPECTS to compare rates of all cancers and advanced cancers for annual, biennial, and 3-year screening. Overdiagnosis, natural history of DCIS, prognostic indicators of breast tumors not impacting quality of life: PRoGram- will use radiomics, genomics and pathomics to develop a greater understanding of the variability of the non-advanced cancers diagnosed in the TMIST population, including DCIS. It is hoped that this model will provide greater understanding of the risk of poor outcomes for women diagnosed with lower risk cancers, including DCIS. Citation Format: Etta Pisano, Constantine Gatsonis, Mitchell Schnall, Melissa Troester, Elodia Cole, Jean Cormack, Ilana Gareen, Martin Yaffe, Laura Collins, Amarinthia Curtis, Ruth Carlos, Kathy Miller, Christopher Comstock. Addressing USPSTF 2023 Identified Key Gaps in Knowledge in Breast Cancer Screening through TMIST (ECOG-ACRIN EA1151) or its Ancillary Studies [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO3-19-03.
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Fogal, Alex Alves. "O MÉTODO CRÍTICO DE ANTONIO CANDIDO E A ANÁLISE DA FORMA POÉTICA." Via Atlântica, no. 35 (July 10, 2019): 13–25. http://dx.doi.org/10.11606/va.v0i35.154614.

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O objetivo desse artigo é refletir sobre método crítico de Antonio Candido especificamente no que diz respeito aos textos poéticos. Para isso, serão analisados dois textos pouco estudados do autor: Na sala de Aula e O estudo analítico do poema. O foco é tentar demonstrar que esses dois livros, apesar de curtos, demonstram a mesma força crítica que Antonio Candido apresenta em suas obras mais conhecidas. Neles, o crítico ressalta a importância do apego à matéria textual na análise dos poemas, apresentando um modelo de análise que deve sempre ter o concreto como ponto de partida. Junto a isso, coloca em evidência uma noção de forma poética fundamentada por uma reflexão dialética, oposta à ideia de que poesia é somente um jogo de linguagem ou um malabarismo técnico.
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Goddu, André. "Ludwik Antoni Birkenmajer and Curtis Wilson on the Origin of Nicholas Copernicus’s Heliocentrism." Isis 107, no. 2 (June 2016): 225–53. http://dx.doi.org/10.1086/687031.

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11

Lafer, Celso. "Novas considerações sobre O albatroz e o chinês." Revista USP, no. 118 (September 3, 2018): 49–62. http://dx.doi.org/10.11606/issn.2316-9036.v0i118p49-62.

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O artigo destaca a importância de O albatroz e o chinês, o último livro que Antonio Candido organizou e publicou, realçando que se insere com alta qualidade em seu percurso de crítico literário e pensador da cultura. Com esse objetivo, explora os nexos memória/análise que caracterizam tanto os ensaios mais longos da segunda parte do livro – que tratam de obras da literatura portuguesa e da presença cultural em nosso país de figuras da intelectualidade portuguesa –, quanto os ensaios mais curtos da terceira parte – que mesclam textos de testemunho e análises literárias e culturais.
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Silva, Luciene Maria, and Daiane Rosário. "A produção documental de Antonio Olavo: lutas e memórias do povo negro." Revista Brasileira de Pesquisa (Auto)biográfica 6, no. 18 (September 6, 2021): 490–508. http://dx.doi.org/10.31892/rbpab2525-426x.2021.v6.n18.p490-508.

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A contribuição do cinema documentário para a compreensão de fatos históricos e pautas contemporâneas tem se confirmado nos últimos anos com uma produção significativa de filmes, sobre temas variados. Este artigo aborda a obra do cineasta baiano Antonio Olavo, realizador de cinco filmes documentários de longa metragem, uma série para TV e diversos curtas e médias-metragens sobre a história social e, particularmente, a memória negra no Brasil. Buscamos compreender a trajetória profissional do cineasta entrelaçada com sua história de vida, as concepções sobre o fazer cinematográfico e as esferas de influências incorporadas em sua obra. Para isso apresentamos seus principais filmes, destacando a série documental Travessias Negras (2017) sobre trajetórias particulares de estudantes universitários cotistas, buscando referências nas narrativas que se articulam em continuidades e rupturas, evidenciando sentidos diante do padrão de discriminação racial que se faz presente na sociedade brasileira. Privilegiamos o entendimento sobre cinema e narratividades a partir de autores como Xavier (2003), Bernadet (2017), Benjamin (1994), Matos (2001), entre outros, e utilizamos entrevistas com o cineasta colocando em perspectiva suas percepções acerca das lutas históricas de resistência, sobre preconceito, racismo, políticas afirmativas e cinema negro.
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Miramontes Olivas, Adriana, Juan De Dios Mora, and Deborah Caplow. "Exodus to the “Promised Land:” Of the Devil and Other Monsters in Juan de Dios Mora’s Artworks." Contemporaneity: Historical Presence in Visual Culture 6 (November 30, 2017): 58–72. http://dx.doi.org/10.5195/contemp.2017.222.

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Juan de Dios Mora is a printmaker and a senior lecturer at The University of Texas at San Antonio, where he began teaching painting, drawing, and printmaking in 2010. Mora is a prolific artist whose prints have been published in numerous venues including the catalogs New Arte Nuevo: San Antonio 2010 and New Art/Arte Nuevo San Antonio 2012. In 2017, his work was exhibited at several venues, including the McNay Art Museum in San Antonio, Texas in Juan Mora: Culture Clash (June 8–August 13, 2017) and at The Cole Art Center, Reavley Gallery in Nacogdoches, Texas, in Juan de Dios Mora (organized by the Art Department at the Stephen F. Austin State University School of Art, January 26–March 10, 2017). In 2016, Mora participated in the group show Los de Abajo: Garbage as an Artistic Source (From the Bottom: Garbage as an Artistic Source) at the Guadalupe Cultural Arts Center in San Antonio (June 10–July 29, 2016). Mora also curates the show Print It Up, which he organizes in the downtown area of San Antonio, thereby granting unprecedented exposure to numerous artists. For this exhibition, Mora mentors both students and alumni, guiding them through the exhibition process—from how to create a portfolio, frame and install artworks, to contracting with gallery owners, and selling artworks to the public. Adriana Miramontes Olivas is a doctoral student in the Department of the History of Art and Architecture at the University of Pittsburgh. She earned her BA at the University of Texas at El Paso and her MA at the University of Texas at San Antonio. Her research is in modern and contemporary global art with a focus on Latin America, gender studies, sexuality, and national identity.Dr. Deborah Caplow is an art historian and curator, and the author of a book about the Mexican printmaker, Leopoldo Méndez (Leopoldo Méndez: Revolutionary Art and the Mexican Print, University of Texas Press). She teaches art history at the University of Washington, Bothell. Areas of scholarship include twentieth-century Mexican art, the intersections between art and politics, and the history of photography. Currently, she is researching contemporary printmaking in Oaxaca, Mexico.
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RUTA, RAFAŁ. "An overview of Scirtidae (Coleoptera) described by Antoine Joseph Jean Solier (1792–1851)." Zootaxa 4767, no. 4 (April 29, 2020): 563–77. http://dx.doi.org/10.11646/zootaxa.4767.4.6.

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In 1849 a French entomologist, Antoine Solier, described 11 species of Scirtidae collected in Chile by Claude Gay. Based on examination of type specimens deposited in the Museum national d’Histoire naturelle (MNHN) in Paris, 9 species: Contacyphon luteolineatus, C. parvus, C. tristis, Pseudomicrocara lunata, P. obliquata, P. torquata, and Elodes rousseli are briefly described with emphasis on male or female genitalia. Morphological details are illustrated. Type specimens of two species: Contacyphon maculatus and Elodes velutina were not found in the collection of MNHN. Two new synonyms were established: Contacyphon maculicornis (Solier, 1849) is a junior synonym of Pseudomicrocara patagonica (Curtis, 1838), and Cyphon testaceus Solier, 1849 is a junior synonym of Pseudomicrocara livida (Fabricius, 1775). Lectotypes of most species described by Solier are designated.
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Romualdo Soares, Deyse Mara, Cleide Jane De Sá Araújo Costa, and Luís Paulo Leopoldo Mercado. "Perspectiva de discentes do curso de Pedagogia sobre a tutoria e interação na EAD (Perspective of students from the Pedagogy course on tutoring and interaction in EAD)." Revista Eletrônica de Educação 15 (November 30, 2021): e4988058. http://dx.doi.org/10.14244/198271994988.

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e4988058Distance education (EAD) is based on the interaction between students and teachers, engaged in a link that determines the access that leads to this process of teaching and knowledge. In this scenario, tutoring stands out as one of the most relevant issues to be studied and addressed, as there is a need to train these professionals to work in this type of teaching. Thus, the research aims to analyze the role of online tutoring and its interactions (narratives) in an elective discipline of the classroom Pedagogy course, from a public higher education institution in the state of Alagoas, in the understanding of its students. With a qualitative approach and exploratory character, the research had as subjects seven students of the course. The instruments of data collection were: questionnaire and observation of interactions (narratives) of students in the forums. The analysis took place in an interpretative way using the Sobek software to assist in the analysis, following the categories: tutoring; interactions in the virtual learning environment; teacher-tutor interaction and students. For students, the experience of acting in tutoring was a moment of learning about this role; considered that in some mini courses there was not; emphasized that the role of tutoring is ingrained in mediating the knowledge of EAD students. It is relevant to reflect on the inclusion of disciplines on distance learning in the curriculum of universities, in the process of initial teacher training.ResumoA educação a distância (EAD) está fundamentada na interação entre os estudantes e professores, engajados num elo que determina o acesso nesse processo de ensino e conhecimento. Nesse cenário, a tutoria se destaca como uma das relevantes questões a ser estudada e abordada, pois, há a necessidade de formar esses profissionais para atuarem nessa modalidade de ensino. Diante disso, o artigo tem o objetivo analisar o papel da tutoria online e suas interações de narrativas, de acordo com a compreensão dos estudantes em uma disciplina eletiva do curso de Pedagogia, na modalidade presencial, de uma instituição de ensino superior (IES) pública do estado de Alagoas. De abordagem qualitativa e caráter exploratório, o estudo teve como sujeitos, sete estudantes do referido curso. Os instrumentos de coleta de dados foram: questionário e observação das interações dos estudantes nos fóruns. A análise se deu de forma interpretativa utilizando-se do software Sobek para auxiliar na análise, seguindo as categorias: tutoria; interações no ambiente virtual de aprendizagem (AVA); interação professor-tutor e estudantes. O estudo mostrou que para os estudantes, a experiência de atuar na tutoria foi um momento de aprendizagem sobre esse papel; consideraram que em alguns momentos não houve interações entre eles; enfatizaram que o papel da tutoria está arraigado na mediação do conhecimento do aluno da EAD. Torna-se relevante refletir sobre a inserção de disciplinas EAD no currículo das universidades, no processo de formação inicial dos professores.Palavras-chave: Tutoria, Interação, Educação a Distância, Pedagogia.Keywords: Mentoring, Interaction, Distance Education, Pedagogy.ReferencesASSOCIAÇÃO BRASILEIRA DE EDUCAÇÃO A DISTÂNCIA. Censo EAD. BR 2017: relatório analítico da aprendizagem a distância do Brasil. Curitiba: InterSaberes, 2018. Disponível em: http://abed.org.br/arquivos/CENSO_EAD_BR_2018_digital_completo.pdf. Acesso em: 27 jul. 2019.BARROS, Fernanda A.; PARAGUAÇU, Fábio.; NEVES, André; COSTA, Cleide J..Intelligent tools for cooperative learning in the Internet. In: LESTER, James C.; VICARI, Rosa M.; PARAGUAÇU, Fábio. (Ed.). Intelligent tutoring systems. LNSC 3220. Berlin: Springer Verlag, 2004. p. 788-791.BELLONI, Maria Luiza. Educação a distância. Campinas: Autores Associados, 2008.BONK, Curtis J.; DENNEN, Vanessa. Frameworks for research, design, benchmarks, training and pedagogy in web-based distance education. In: MOORE, M.; ANDERSON, W. Handbook of distance education. Mahwah, NJ: Lawrence Erlbaum, 2003. p. 329-346BRASIL. Ministério da Educação. Secretaria de Educação a Distância. Referenciais de qualidade para educação superior a distância. Brasília, DF: MEC, 2009.BRUNO, Adriana Rocha; LEMGRUBER, Márcio Silveira. Dialética professor-tutor na educação on-line: o curso de Pedagogia-UAB-UFJF em perspectiva. Anais... III Encontro Nacional sobre Hipertexto, Belo Horizonte, 29-31 out. 2009. Disponível em: http://www.ufpe.br/nehte/hipertexto2009/anais/a/a-dialeticaprofessor-tutor.pdf. Acesso em: 06 jul. 2019.COSTA, Cleide J.; PARAGUACU, Fábio; PINTO, Anamelea. Experiência interativas com ferramentas midiáticas na tutoria on-line. Em Aberto, v. 22, p. 121-137, 2009.DILLENBOURG. Pierre. What do you mean by ‘collaborative learning. Swrtzerland: University of Geneva, 1999. Disponível em: http://hal.archives-ouvertes.fr/docs/00/19/02/40/PDF/Dillenbourg-Pierre-1999.pdf. Acesso em: 22 jul. 2019.GIANNASI, Maria Júlia. A prática pedagógica do tutor no ensino a distância: resultados preliminares. Virtual Educa: México, 2005IMBERNÓN, Francisco. Formação docente e profissional: formar-se para a mudança e a incerteza. São Paulo: Cortez, 2006.KENSKI, Vani. Educação e tecnologias: o novo ritmo da informação. São Paulo: Papirus, 2013.LUDKE, Menga; ANDRÉ, Marí. Pesquisa em educação: abordagens qualitativas. 2. ed. São Paulo: EPU, 2013.OLIVEIRA, Cármem L; LIMA, João; MERCADO, Luís P. Tutoria online no programa formação continuada de professores em mídias na educação. In: MERCADO, Luís P. (org.) Práticas de formação de professores na educação a distância. Maceió: Edufal, 2008, p. 47-59PRIMO, Alex. O aspecto relacional das interações na web 2.0. Revista da Associação Nacional dos programas de pós-graduação comunicacional. v. 9, ago. 2007a.PRIMO, Alex. Interação mútua e interação reativa: uma proposta de estudo. Porto Alegre: Ed. Editora Sulina, 2007b.SAMPIERI, Roberto H.; COLLADO, Carlos; LUCIO, Maria del Pilar B. Metodologia de pesquisa. 5.ed. Porto Alegre: Penso, 2013.SERAFIM, Maria Lúcia; SOUSA, Robson Pequeno de. Multimídia na educação: o vídeo digital integrado ao contexto escolar. Campina Grande: Eduepb, 2011.SEVERINO, Antonio Joaquin. Metodologia do trabalho científico. 23. ed. São Paulo: Cortez, 2007.SILVA, Cleeyton T. Entre os gregos e eles mesmos: um ensaio sobre identidade e alteridade em A República dos Lacedemônios de Xenofonte. In: XXVI Simpósio Nacional de História. Anais… São Paulo: ANPUH jul. 2011. p. 1-13.VALENTE, José A. Pesquisa, comunicação e aprendizagem com o computador: o papel do computador no processo ensino-aprendizagem. In: ALMEIDA, Maria E.; MORAN, José M. (org.). Interação das tecnologias na educação. Salto para o futuro. Brasília, Ministério da Educação, SEED, 2005, p. 15-35.
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McArthur, Heather, Jorge Henrique Santos Leal, Isaac Chan, Nisha Unni, Stephen Shiao, Joshua Gruber, Samira Syed, et al. "Abstract PO5-19-08: Neoadjuvant HER2-targeted Therapy +/- Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial." Cancer Research 84, no. 9_Supplement (May 2, 2024): PO5–19–08—PO5–19–08. http://dx.doi.org/10.1158/1538-7445.sabcs23-po5-19-08.

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Abstract Background: Immune checkpoint inhibition (ICI) is synergistic with HER2-directed therapy in pre-clinical models. Clinically, pembrolizumab (K)-mediated ICI plus HER2-directed therapy with trastuzumab (H) was safe and demonstrated modest activity in H-resistant HER2-positive (HER2+) metastatic breast cancer. Because ICI may confer more robust activity when administered earlier in the course of disease, H and K administered in the curative-intent, treatment-naive setting may allow for de-escalation of cytotoxics; confer life-long, tumor-specific immunity; and ultimately, improve cure rates. Moreover, the synergy of H and K with paclitaxel (T) may overcome the need for dual HER2-blockade with H plus pertuzumab (P). In this randomized, multicenter, phase II, open-label trial the efficacy and safety of neoadjuvant THP vs THP-K vs TH-K are explored. Methods: Patients (pts) ≥18y with previously untreated, stage II-III, HER2+ breast cancer are being randomized and stratified by clinical nodal status (positive vs. negative) and hormone receptor status (positive vs. negative). In arm A, pts receive T at 80mg/m2 weekly for 12 weeks, H at 8mg/Kg (loading dose) and then 6mg/Kg every 3 weeks x 3 doses, P at 840 mg (loading dose) and then 420mg/Kg every 3 weeks x 3 doses (THP). In arm B, pts receive THP plus K at 200mg every 3 weeks x 4 doses (THP-K). In arm C, pts receive TH-K. After enrollment of 22 pts to arm C, a prespecified interim efficacy analysis was conducted, and enrollment to this arm was subsequently terminated. Enrollment to the other arms continues with 32/58 pts enrolled to arm A and 33/58 pts enrolled to arm B as of 2/14/2023. Definitive surgery is 3-6 weeks after the last dose. After surgery, pts are treated per the treating physician’s discretion per local clinical standard. The primary end point is pathologic complete response (pCR) rate in the breast and axilla (ypT0/Tis ypN0). Secondary end points include pCR rate by ypT0ypN0 and ypT0/Tis, residual cancer burden index, event free survival, breast conserving surgery rate, safety and overall survival. Exploratory correlative studies will characterize potential immune biomarkers predictive of efficacy and/or toxicity. Funding sources: BCRF, Merck NCT03747120 Citation Format: Heather McArthur, Jorge Henrique Santos Leal, Isaac Chan, Nisha Unni, Stephen Shiao, Joshua Gruber, Samira Syed, Namrata Peswani, Navid Sadeghi, Glenda Delgado, Dawn Klemow, Reva Basho, Meredith Carter, Mai Badran, Nasir Qureshi, Jessica Curtin, Joshua Weese, Stephanie Rice, Michelle Phillips, David Chan, Hugo Hool, Dorothy Park, Mary El-Masry, Philomena McAndrew, Swati Sikaria, Laura Spring, Aditya Bardia, Mourad Tighiouart, Farnaz Dadmanesh, Armando Giuliano, Katherine Sanchez, David Page. Neoadjuvant HER2-targeted Therapy +/- Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO5-19-08.
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Grünwald, Barbara T., Curtis McCloskey, Antoine Devisme, Foram Vyas, Geoffroy Andrieux, Kazeera Aliar, Faiyaz Notta, et al. "Abstract PO-107: Fibroblast differentiation trajectories elicit regional tissue states in pancreatic cancer." Cancer Research 81, no. 22_Supplement (November 15, 2021): PO—107—PO—107. http://dx.doi.org/10.1158/1538-7445.panca21-po-107.

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Abstract Intratumoral heterogeneity is a critical frontier in understanding how the tumor microenvironment (TME) propels malignant progression. We recently deconvoluted regional heterogeneity in the human PDAC stroma to assess its role in disease progression and discovered two types of ‘sub-tumor microenvironments’ (subTMEs), called ‘reactive’ and ‘deserted’. These histologically definable tissue states exhibit strong regional relationships with tumor immunity, subtypes, differentiation, and treatment response. Here, we set out to define their cell biological underpinnings through a combination of subTME-specific cancer-associated fibroblast (CAF) models, integrative histopathology, quantitative image analysis, multiOMICs, scRNAseq, and controlled functional assays. Remarkably, the growth patterns of CAF cultures closely recapitulated the characteristic histomorphology of their originating subTMEs, and these distinct phenotypes were accompanied by behavioral differences. Unsupervised graph-based clustering of scRNAseq profiles showed that CAFs largely grouped by their originating subTME yet comprised up to 10 individual clusters. The subTME-specific multi-subpopulation CAF communities self-organized into distinct ‘coordinated states’, represented by cluster-overarching functional profiles and distinct morpho-histological and behavioral phenotypes. These differences originated in cellular differentiation trajectories, with an ‘intermediate’ transitory state evident both in single cell transcriptomics and in situ. Noticeably, this CAF differentiation potential was associated with distinct tumor-related functions and, similar to stem cells, was marked by RNA diversity and pluripotency markers. Therefore, regional TME programs in PDAC appear to result largely from transitions between subpopulation-overarching fibroblast differentiation states that guide multifaceted CAF and immune cell communities into recurrent tissue self-organizational units. Citation Format: Barbara T. Grünwald, Curtis McCloskey, Antoine Devisme, Foram Vyas, Geoffroy Andrieux, Kazeera Aliar, Faiyaz Notta, Grainne O’Kane, Julie Wilson, Jennifer Knox, Sandra Fischer, Thomas Kislinger, Melanie Boerries, Steven Gallinger, Rama Khokha. Fibroblast differentiation trajectories elicit regional tissue states in pancreatic cancer [abstract]. In: Proceedings of the AACR Virtual Special Conference on Pancreatic Cancer; 2021 Sep 29-30. Philadelphia (PA): AACR; Cancer Res 2021;81(22 Suppl):Abstract nr PO-107.
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Loirat, Delphine, Marie Duboys de la barre, Jean-Christophe Thery, Ioana Hrab, Christelle Jouannaud, Jean-Loup Mouysset, Laura Salabert, et al. "Abstract P4-01-20: Phase IV study evaluating talazoparib in patients with locally advanced or metastatic negative HER2 breast cancer and a somatic or germline BRCA1/2 mutation (ViTAL) – Analysis of cohort 1 according to hormonal receptor status." Cancer Research 83, no. 5_Supplement (March 1, 2023): P4–01–20—P4–01–20. http://dx.doi.org/10.1158/1538-7445.sabcs22-p4-01-20.

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Abstract Background: Talazoparib (TALA) is a highly potent, dual-mechanism PARP inhibitor that has demonstrated clinical benefit in EMBRACA Phase III trial for patients with germline BRCA1/2 mutated locally advanced or metastatic HER2- breast cancer. Objective: The aim of the study is to ensure the effectiveness and safety of TALA in real-life setting among patients with locally advanced or metastatic HER2- breast cancer, with somatic or germline BRCA1/2 mutation. Methods: ViTAL is an ambispective, multicentric, longitudinal, phase IV study. It includes two ambispective cohorts: - Cohort 1: patients treated through the French Early Access Program and inclusion of patients with somatic BRCA1/2 mutation was allowed. - Cohort 2: patients treated according to the European Marketing Approval granted in 09/21/2021. Here we present the results of the primary and some secondary endpoints for cohort 1. Results: From November 2018 to May 2021, 86 patients were included in Cohort 1, with updated results after a median follow-up of 17.3 months (11.2 - 24.4). Patients’ characteristics are 53.5% of ER+ BC/46.5% of TNBC (refer to the table). The median Time to Treatment Discontinuation (mTTD) was 9.0 months [range 6.0; 11.5] with 37.7% of patients still on treatment at 12 months. Subgroup analysis shows similar mTTD according HR status, germline vs somatic mutation and prior platinum exposure (refer to the table). The Clinical Benefit Rate assessed by the investigators is 82.4% (Complete Response for 25.7%, Partial response R for 32.4% and stable disease for 24.3%). The median of duration of CNS metastases control was 6.6 months, and 80.0% of patients had control of CNS metastases during TALA. Out of the 85 treated patients, 69 patients (80,2%) experienced a TALA permanent discontinuation for progressive disease (84.1%), toxicity (10.1%), cancer-related death (1.4%), or other reasons (1.4%). After discontinuation of TALA, 65.1% of patients received a subsequent treatment with a TTD of 2.3 months [1.7; 2.7]. The most common subsequent treatments were non-platinum chemotherapy (64.3%), platinum chemotherapy (19.6%) and others (19.1%). At least one adverse events (AEs) was recorded in 74.4% of patients. Hematologic AEs (any grade) occurred in 48.8% (anemia 27.9%, thrombocytopenia 12.8%, neutropenia 10.5%). Most common non-hematologic AEs were alopecia (8.1%) and asthenia (7.0%). Related Serious Hematologic AEs occurred in 10 patients (11.6%) including 7 (8.1%) Anemia. Related Serious Non-hematologic AEs (vomiting, pyelonephritis and ascitis) were seen in 3 patients (3.6%). AEs associated with temporary drug interruption, dose modification and permanent drug discontinuation occurred in 36 (41.9%), 24 (27.9%), and 7 (10.1%) patients respectively. The mOS is expected to be reached at the time of the congress, with 51.9% of patients still alive at 24 months. Conclusions: ViTAL is the largest study that reports real-word data with TALA. Outcomes and safety in Cohort 1 are consistent with the results of EMBRACA study and give additional data on subgroups of interest (ie patients previously treated with carboplatin, presence of CNS). (Litton et al. NEJM 2018) mTTD on subgroups of interest Patients’ characteristics Citation Format: Delphine Loirat, Marie Duboys de la barre, Jean-Christophe Thery, Ioana Hrab, Christelle Jouannaud, Jean-Loup Mouysset, Laura Salabert, Pauline Soibinet, Audrey Mailliez, Romain Valery, Anne Creisson, Cristian Villanueva, Nadine Dohollou, Jean-david Fumet, Thomas grellety, Nathalie Perez-staub, Emma Lachaier, Aurore Iltis-roux, Miguel delbado, Abeer Najem, Romuald Le Scodan, Elsa Curtit, kais aldabbagh, Pascal Pujol, thibault DE LA MOTTE ROUGE. Phase IV study evaluating talazoparib in patients with locally advanced or metastatic negative HER2 breast cancer and a somatic or germline BRCA1/2 mutation (ViTAL) – Analysis of cohort 1 according to hormonal receptor status [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr P4-01-20.
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Moore, Rachel, Anna Blümel, Elspeth Ward, Elizabeth Sainsbury, Emer Conroy, Fergal O’Brien, Caroline Curtin, et al. "Abstract PO2-24-04: Exploring the role and therapeutic potential of Ubiquitin Specific Peptidase 11 (USP11) in estrogen receptor positive breast cancer." Cancer Research 84, no. 9_Supplement (May 2, 2024): PO2–24–04—PO2–24–04. http://dx.doi.org/10.1158/1538-7445.sabcs23-po2-24-04.

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Abstract Dysregulated estrogen receptor (ER) function is a key feature of 70% of breast cancers. In this setting ER primarily functions as a growth-controlling transcription factor driving pro-tumorigenic properties, thus there is a need to identify novel modulators of ER transcriptional activity as alternative therapeutic options. Previously, we showed a significant association between high ubiquitin specific protease 11 (USP11) expression and poor survival in ER+ breast cancer patients, but not in ER- patients, indicating a role for USP11 in ER+ subtypes. However, the precise role of USP11 in controlling ER function remains undescribed. To interrogate USP11 function in ER+ breast cancer we generated a CRISPR USP11 knockout MCF7 breast cancer cell line. Our results showed for the first time that USP11 knockout significantly reduces proliferation, induces G2 cell cycle arrest and apoptosis, abrogates ERα transcriptional activity, significantly impairs cell migration and invasion, whilst also impairing MCF7 cancer stem-cell like properties and malignant transformation in vitro. In addition, we also observed significant dysregulation of epithelial-mesenchymal transition-related markers including E-cadherin, N-cadherin, Snail and Slug. Using RNA-seq of MCF7 cells +/- estradiol, +/- stable USP11 knockdown we identified dysregulated pathways in protein binding, cell adhesion molecule binding and cell cycle regulation following USP11 modulation. Of note, gene expression analysis indicated NCOA3 as the most differentially expressed coding gene. Further validation confirmed a significant reduction in NCOA3- encoded Steroid receptor coactivator- 3 (SRC-3) protein expression following USP11 modulation with immunocytochemical analysis also indicating co-localisation within the nucleus. Frequently upregulated in breast cancer and associated with poor outcome, SRC-3 promotes ER transcriptional activity and co-activates a wide range of additional pro-tumorigenic transcription factors. Thus, SRC-3 modulation offers an attractive therapeutic target in breast cancer. This finding may present a novel role for USP11 in controlling SRC-3 and therefore associated ER transcriptional activity. We then aimed to explore the therapeutic potential of USP11. Although rare in primary breast cancer, activating mutations in the ER ligand-binding domain have recently been linked to recurrent, anti-endocrine resistant disease and metastasis. As such cancers remain dependent on ER-signalling for proliferation, but are resistant to ER targeted therapies, we identified USP11 as a potential novel therapeutic target. Using CRISPR knock-in ER mutant MCF7 cell lines expressing the four most common ER activating mutations, we demonstrated that USP11 knockdown continues to significantly reduce proliferation and abrogates mutant ERα transcriptional activity. We then explored amphipathic cell penetrating peptide RALA encapsulation as a delivery method for siRNA targeting USP11. Optimisation of nanoparticle delivery in the Y537S ER-mutant MCF7 breast cancer cell line achieved significant knockdown of USP11 and ER- related target genes including TFF1, PgR, GREB1 and PKIB in 2D with minimal associated cellular toxicity. To overcome the siRNA-related issues of rapid clearance upon systemic delivery, we then explored the use of a freeze-dried collagen-based scaffold model as an in vitro 3D RALA-encapsulated siRNA delivery system. Here we observed successful delivery of nanoparticle to MCF7 breast cancer cells, with a significant reduction in USP11 mRNA expression. Bio-compatible scaffold- facilitated delivery may therefore offer a more feasible translation of this siRNA-based therapeutic. Overall, this study highlights a novel role for USP11 in various oncogenic pathways. USP11 may therefore offer a novel therapeutic target to be exploited for the management of ER-positive breast cancer, including ER mutant breast cancer. Citation Format: Rachel Moore, Anna Blümel, Elspeth Ward, Elizabeth Sainsbury, Emer Conroy, Fergal O’Brien, Caroline Curtin, Simak Ali, Helen McCarthy, William Gallagher, Darran O'Connor. Exploring the role and therapeutic potential of Ubiquitin Specific Peptidase 11 (USP11) in estrogen receptor positive breast cancer [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO2-24-04.
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Guccione, Caitlin, Lucas Patel, Daniel McDonald, Cameron Martino, Antonio González, Gregory D. Sepich-Poore, Rob Knight, and Kit Curtius. "Abstract 4954: Improving microbial detection in cancer tissue samples with computational host depletion using the pangenome." Cancer Research 84, no. 6_Supplement (March 22, 2024): 4954. http://dx.doi.org/10.1158/1538-7445.am2024-4954.

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Abstract Sensitive removal of host genetic information (i.e., host depletion) is a key first step towards accurate classification of potential microbial DNA sequences in low-biomass samples, such as human tumors. Inadequate filtration of human reads prior to microbial classification can cause false positives, biasing biological conclusions. Previous computational host depletion pipelines predominantly employed the human reference genome GRCh38 (hg38), which lacks genetic diversity of the human population and excludes substantial portions of the Y-chromosome. To address these deficiencies, we constructed a pipeline to maximally remove human reads that incorporates hg38, the first complete genome build T2T-CHM13v2.0 (T2T), and the 47 diploid genomes from the Human Pangenome Reference Consortium (HPRC) [1]. Reads passing maximal host depletion and quality control are considered sufficiently cleaned for downstream microbial analyses. We first evaluated the specificity of our pipeline by simulating Illumina whole genome sequencing (WGS) data from 10 heldout HPRC humans, whose genomes were excluded from the host depletion pipeline. We found significant improvement in the median number of human reads remaining across successive host depletion methods (hg38, 0.05369%; hg38+T2T, 0.00535%; hg38+T2T+HPRC, 0.00093%). For sensitivity, we applied our pipeline to simulated data from 962 microbes in the FDA-ARGOS dataset and found minimal removal of true microbial reads (median 99.9390% reads retained). As a real world example, we evaluated our pipeline on 583 metastatic colorectal cancer tissue (WGS) samples from the Hartwig Medical Foundation (HMF) database (median 106X coverage)[2] and found successive decreases in median number of reads retained (hg38, 185,135; hg38+T2T, 92,951; hg38+T2T+HPRC, 10,314). Using Woltka for taxonomic classification against database RefSeq210, we assessed biological sex similarity across the HMF samples using Robust Aitchison PCA (RPCA). Notably, microbial data following hg38-only host depletion showed significant microbial differences between male and female-labeled samples (p=0.00001), which was biologically unexpected. However, our updated pipeline (hg38+T2T+HPRC) removed the false sex-based separation in the microbial data (p=0.1837). Thus, utilization of diverse sets of complete human genomes for computational host depletion can mitigate artifactual bias, enabling more sensitive and specific host-microbe conclusions in cancer research. [1] Liao, et al. Nature 617, 312-324 (2023). [2] Priestley, et al. Nature 575, 210-216 (2019). Citation Format: Caitlin Guccione, Lucas Patel, Daniel McDonald, Cameron Martino, Antonio González, Gregory D. Sepich-Poore, Rob Knight, Kit Curtius. Improving microbial detection in cancer tissue samples with computational host depletion using the pangenome [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 4954.
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Flick, Matthew, Taylor Weiskittel, Kevin Meng-Lin, Fulvio D'Angelo, Francesca Caruso, Shannon Ensign, Mylan Blomquist, et al. "Abstract 5621: Multi-parametric MRI maps regional heterogeneity of high grade glioma phenotypes." Cancer Research 83, no. 7_Supplement (April 4, 2023): 5621. http://dx.doi.org/10.1158/1538-7445.am2023-5621.

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Abstract High grade glioma (HGG) represents a group of devastating diseases with dismal prognosis. Surgical resection of the contrast enhancing (CE) region of HGG remains the mainstay of treatment, but recurrence inevitably arises from the unresected non-contrast enhancing (NE) region, surgically inaccessible due to cancer cell invasion into healthy brain tissue. Due to its critical role in recurrence, understanding of the NE region is central to the improvement of clinical outcomes. We reveal the biological characteristics of this region through image localized multi-regional sampling. We linked microenvironmental characteristics measured by multi-parametric MRI to genomic mutations and transcriptional phenotypes using mixed effect modeling which allowed us to control for individualized patient effects. We first confirmed that T2 is a significant indicator of IDH mutation status in the NE region, being the first description of such a relationship in a HGG cohort. We found the combination of EGFR amplification and CDKN2A homozygous loss was associated with a significantly lower mean diffusivity (MD) compared to double wild type tumors in the NE region, indicating the presence of greater cellular packing and proliferation in EGFR amplification/CDKN2A loss regions. Finally, using single cell pathway based tumor classifications, we showed that nK2, a DSC-MRI metric representing cell size heterogeneity, correlated positively with neuronal signature and negatively with glycolytic/plurimetabolic signature within the NE tumor, indicating that glycolytic/plurimetobolic tumors possessed a high amount of cell size heterogeneity compared to neuronal samples. This hypothesis was supported using digital reference object (DRO) modeling which confirmed that cell size and heterogeneity drove the differential nK2 signal between neuronal and glycolytic/plurimetabolic samples. We identified immune cell infiltrate as one possible mechanism of increased cell size heterogeneity using transcriptomic signature analysis which found more immune cell signatures within glycolytic/plurimetobolic tumors compared to neuronal. Collectively this study demonstrates the central role of multi-parametric MRI as a non-invasive measure of tumor biology and a tool for understanding the clinically critical NE region which can then inform new therapies targeting this region of HGG recurrence. Citation Format: Matthew Flick, Taylor Weiskittel, Kevin Meng-Lin, Fulvio D'Angelo, Francesca Caruso, Shannon Ensign, Mylan Blomquist, Luija Wang, Christopher Sereduk, Gustavo De Leon, Ashley Nespodzany, Javier Urcuyo, Ashlynn Gonzalez, Lee Curtin, Kyle Singleton, Aliya Anil, Natenael Simmineh, Erika Lewis, Teresa Noviello, Reyna Patel, Panwen Wang, Junwen Wang, Jennifer Eschbacher, Andrea Hawkins-Daarud, Pamela Jackson, Kris Smith, Peter Nakaji, Bernard Bendok, Richard Zimmerman, Chandan Krishna, Devi Patra, Naresh Patel, Mark Lyons, Matthew Neal, Kliment Donev, Maciej Mrugala, Alyx Porter, Scott Beeman, Yuxiang Zhou, Leslie Baxter, Christopher Plaisier, Jing Li, Hu Li, Anna Lasorella, Chad Quarles, Kristin Swanson, Michele Ceccarelli, Antonio Iavarone, Nhan Tran, Leland Hu. Multi-parametric MRI maps regional heterogeneity of high grade glioma phenotypes. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 5621.
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Sanborn, Rachel E., Saiama N. Waqar, Byoung Chul Cho, Benjamin Besse, Koichi Goto, Yongsheng Wang, Se-Hoon Lee, et al. "Abstract 2166: Analysis of ctDNA next generation sequencing (NGS) for predicting response to amivantamab and lazertinib among patients with EGFR-mutant NSCLC after progression on osimertinib and platinum-based chemotherapy (CHRYSALIS-2 Cohort A)." Cancer Research 83, no. 7_Supplement (April 4, 2023): 2166. http://dx.doi.org/10.1158/1538-7445.am2023-2166.

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Abstract Background: Among post-osimertinib (osi), chemotherapy-naïve patients (pts) treated with amivantamab (ami) and lazertinib (laz) in CHRYSALIS Cohort E, NGS of baseline ctDNA and tumor tissue revealed pts with identified EGFR/MET-based resistance (eg, EGFR C797S or MET amplification) were slightly more likely to respond versus those without EGFR/MET-based resistance (ORR=47% vs 29%), but about half of responders had unknown resistance mechanisms (Bauml JCO 2021; 39:15_suppl, 9006). In CHRYSALIS-2 Cohort A (NCT04077463), ami + laz demonstrated an ORR of 33% in the post-osi and platinum-based chemotherapy population (Shu JCO 2022; 40:16_suppl, 9006). This analysis investigated whether EGFR/MET-dependent resistance by ctDNA correlated with response. Methods: Cohort A examined ami + laz in EGFR exon19del or L858R mutated advanced NSCLC whose disease progressed on osi as well as platinum-based chemotherapy. ORR was verified through blinded independent central review. Plasma samples were collected prior to treatment; ctDNA was analyzed by Guardant360. Results: A total of 162 pts were enrolled; of these, 110 (68%) had analyzable ctDNA data, with most common mutations observed in EGFR and TP53. Twenty-eight (25%) pts had resistance categorized as EGFR/MET-dependent and 31 (28%) as EGFR/MET-independent; no genetic resistance mechanism was identified in 51 (46%). The ORR was 29% and 26% in EGFR/MET-dependent and independent pts, respectively. ORR in pts with an unknown resistance mechanism was 39% (Table). Conclusions: Among pts who progressed on osi and platinum-based chemotherapy, genetic profiling of osi resistance by ctDNA did not predict response, with many responders having unknown resistance mechanisms. These results suggest alternative biomarker approaches are needed to identify pts most likely to benefit from ami + laz. Table. ORR by type of resistance mechanism Resistance mechanism n PR ORRa EGFR/MET-dependentb 28 8 29% EGFR/MET-independent 31 8 26% Unknown 51 20 39% All patients 110 36 33% aResponses were assessed by blinded independent central review per RECIST v1.1. bIncludes co-occurring ‘independent’ resistance mechanisms. EGFR, epidermal growth factor receptor; MET, mesenchymal epithelial transition factor; ORR, objective response rate; PR, partial response. Citation Format: Rachel E. Sanborn, Saiama N. Waqar, Byoung Chul Cho, Benjamin Besse, Koichi Goto, Yongsheng Wang, Se-Hoon Lee, Melina E. Marmarelis, Yuichiro Ohe, Dong-Wan Kim, Antonio Calles, Joel Neal, Christina S. Baik, Pasi A. Janne, Joshua C. Curtin, Bharvin Patel, Mike Gormley, S. Martin Shreeve, Joshua M. Bauml, Roland E. Knoblauch, James Chih-Hsin Yang. Analysis of ctDNA next generation sequencing (NGS) for predicting response to amivantamab and lazertinib among patients with EGFR-mutant NSCLC after progression on osimertinib and platinum-based chemotherapy (CHRYSALIS-2 Cohort A) [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 2166.
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Blomquist, Mylan R., Leland S. Hu, Fulvio D'Angelo, Taylor M. Weiskittel, Francesca P. Caruso, Shannon P. Fortin Ensign, Christopher Sereduk, et al. "Abstract 1507: Multiregional sampling of high grade glioma identifies regional biologic signatures." Cancer Research 83, no. 7_Supplement (April 4, 2023): 1507. http://dx.doi.org/10.1158/1538-7445.am2023-1507.

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Abstract High grade gliomas (HGG) are aggressive primary brain malignancies typified by diffuse invasion, genetic heterogeneity, and a universally fatal outcome. MRI-defined contrast-enhancing (CE) tumor burden serves as the clinical standard that guides maximal surgical resection and post-therapy response assessment. However, HGGs also comprise an invasive non-enhancing (NE) tumor margin that extends beyond the CE core and harbors the cells that contribute to recurrence. Sampling restrictions have hindered the comprehensive study of these NE HGG cell populations driving tumor progression. Herein, we present an integrated multi-omic analysis of 313 spatially matched multi-regional CE and NE tumor biopsies from 68 HGG patients, performing whole exome and RNA sequencing of both IDH wild-type and IDH mutant HGGs. We report spatially restricted molecular profiles in IDH-mutant HGG, highlighting a concern for sampling bias given the importance of molecular diagnosis and prognostication in IDH-mutant HGG. Regardless of IDH status, we found that NE tumor regions harbored the highest proportion of private mutations, which reflects an increased development of regional genomic complexity in infiltrative tumor. The multiregional genomic profiling of our IDH wild-type HGG cohort reveals that EGFR and NF1 somatic alterations occur as mutually exclusive events in 98.7% of tumors. However, we resolved rare low allele frequency co-alterations of EGFR and NF1 within the NE region. We find this co-occurrence enriched in recurrent tumors, pointing to the early emergence of NF1 inactivation in the NE regions. We constructed genomic models predictive of recurrent disease from both NE and CE regions, which highlight the occurrence of clonal EGFR copy number alterations and NF1 loss as clonal or subclonal events, respectively, emphasizing the regional and temporal complexity of well-studied canonical driver alterations. We detailed the spatially unique acquisition of multiple distinct EGFR alterations giving rise to intra-tumoral EGFR mosaicism, a challenge in the implementation of EGFR directed therapies. Our study also identified two transcriptomic clusters delineated by the significant overrepresentation of neuronal (NEU) and glycolytic/plurimetabolic (GPM) pathway-based functional states in the NE region. NE regions of the NEU subtype harbor the greatest proportion of private mutations, suggesting these infiltrative tumor cells accumulate alterations without clonal expansion. GPM populations conversely displayed a less branched phylogeny and were transcriptionally enriched in immune cell signatures. This phenotypic dichotomy between GPM and NEU populations supports the growing body of evidence that invasive GBM cells either take on a neuronal phenotype for active invasion or a more metabolic phenotype involving interaction with astrocytes, other glial cells, and infiltrating immune cells. Citation Format: Mylan R. Blomquist, Leland S. Hu, Fulvio D'Angelo, Taylor M. Weiskittel, Francesca P. Caruso, Shannon P. Fortin Ensign, Christopher Sereduk, Gustavo De Leon, Lee Curtin, Javier Urcuyo, Ashlynn Gonzalez, Ashley Nespodzany, Teresa Noviello, Jennifer M. Eschbacher, Kris A. Smith, Peter Nakaji, Bernard R. Bendok, Richard S. Zimmerman, Chandan Krishna, Devi Patra, Naresh Patel, Mark Lyons, Kliment Donev, Maciej Mrugala, Alyx Porter, Anna Lasorella, Kristin R. Swanson, Michele Ceccarelli, Antonio Iavarone, Nhan L. Tran. Multiregional sampling of high grade glioma identifies regional biologic signatures [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 1507.
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Curti, Antonio, Alessandro Rambaldi, Chiara Cattaneo, Roberto Cairoli, Matteo Della Porta, Patrizia Chiusolo, Federico Lussana, et al. "Abstract CT025: NMS-03592088, a novel, potent FLT3, KIT and CSF1R inhibitor with activity in FLT3 positive acute myeloid leukemia patients with prior FLT3 inhibitor experience." Cancer Research 83, no. 8_Supplement (April 14, 2023): CT025. http://dx.doi.org/10.1158/1538-7445.am2023-ct025.

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Abstract Background: FLT3 mutations occur in approximately 30% of AML patients and are associated with aggressive disease. Despite the approval of midostaurin and gilteritinib, the prognosis for FLT3+ patients with relapsed or refractory disease is poor. NMS-088 is a novel, potent FLT3, KIT and CSF1R inhibitor with superior preclinical activity compared with approved FLT3 inhibitors in different FLT3-driven models. In addition, NMS-088 is active on FLT3 resistance mutation F691L. Dose escalation results from a Phase I/II study to establish safety, dose selection and preliminary clinical activity for NMS-088 in patients with R/R AML and CMML are described. Methods: In the Phase I 3+3 escalations, NMS-088 is administered daily for 21 of 28 days (schedule A) or continuously (schedule B). Patients must have R/R AML or CMML unsuitable for standard therapy. The primary objective is the MTD or MAD as assessed by DLTs. Secondary endpoints include safety, PK and ELN response. Results: as of January 26, 44 R/R AML or CMML patients were treated at doses from 20 to 360 mg/day in A or from 120 to 250 mg/day in B. Median age was 64 yrs, 41 pts had AML and 3 pts had CMML, median number of prior lines was 2 (range 1 to 10). FLT3 mutations were present in 24 out of 41 AML pts (20 FLT3-ITD, 2 FLT3 D835 and 2 FLT3-ITD and D835). The majority of pts with FLT3+ AML had received prior FLT3 inhibitors (86.4%). NMS-088 showed manageable safety with no MTD characterized. One pt had DLT (abnormal posture, decreased activity, dyspnea G3 and eyelid ptosis G1) at 360 mg in A (at day 21) and one pt had DLT (eyelid ptosis G3) at 180 mg in B (at day 29), both suggestive for myasthenic syndrome. Three additional pts experienced possible myasthenic syndrome at doses ≥ 180 mg. Overall the most frequent treatment emergent related adverse events (≥10%) were nausea (any grade 20.5%), vomiting (13.6%), asthenia (11.4%). Discontinuations due to related AEs were as follows: 2 DLT pts per protocol, 2 pts due to nausea (G1; day 161 at 270 mg) and myasthenia gravis (G3; day 39 at 300 mg in a pt with baseline AChR antibodies). There was a dose-dependent trend for response. A total of 5 out of 12 evaluable pts with FLT3+ AML treated at dose ≥ 300 mg achieved a response with 2 CRi, 1 CRi/MLFS and 2 MLFS. Remarkably, all these pts had received prior midostaurin and 2 pts received both midostaurin and gilteritinib. Two pts with response withdrew from treatment to receive HSCT (DoR 1.0+ mos each). For other responding pts DoR was 1.3, 2.8 and 7.9 mos. Conclusions: NMS-088 showed clinical efficacy in pts with FLT3+ R/R AML, including pts who have failed prior FLT3 inhibitors. Together with the manageable safety observed, these results warrant further development of this drug including potential as a novel valuable therapeutic option for pts who have exhausted available treatments. The trial is currently opened for enrollment (NTC03922100). Citation Format: Antonio Curti, Alessandro Rambaldi, Chiara Cattaneo, Roberto Cairoli, Matteo Della Porta, Patrizia Chiusolo, Federico Lussana, Marta Ubezio, Valentina Mancini, Isabel Cano, Carmen Besliu, Christian Hove Claussen, Rosalinda Gatto, Patrizia Crivori, Elena Colajori, Alessio Somaschini, Cristina Davite, Antonella Isacchi, Elena Ardini, Lisa Mahnke, Pau Montesinos. NMS-03592088, a novel, potent FLT3, KIT and CSF1R inhibitor with activity in FLT3 positive acute myeloid leukemia patients with prior FLT3 inhibitor experience [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 2 (Clinical Trials and Late-Breaking Research); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(8_Suppl):Abstract nr CT025.
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Corrêa, Mirele, Jessiel Odilon Junglos, and Gicele Maria Cervi. "Políticas Educacionais e Proesde: Uma experiência de formação docente no Estado de Santa Catarina (Educational Policies and Proesde: An experience of teacher training in the State of Santa Catarina)." Revista Eletrônica de Educação 14 (September 9, 2020): 3924129. http://dx.doi.org/10.14244/198271993924.

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The text proposes to report a teacher training experience with the Proesde/Educational Degree (Higher Education Program for the Regional Development of the State of Santa Catarina), linked to the Regional University of Blumenau - FURB. In 2018, this program sought to qualify undergraduate students to work in front of the BNCC (Common National Curricular Base), configured as a public policy for standardizing the national curriculum. Within the planned training program, a meeting had been provided that covered other flows of the hitherto instituted and discussed about BNCC, problematizing the curriculum through the post-critical epistemological bias, which interprets it as being a field of disputes for the meaning of what comes curriculum and how it should operate in the school institution. This perspective understands that political decisions are determined by discourses of truth that crystallize common and totalitarian norms that deserve to be questioned, giving rise to the antagonisms of what was sedimented as a result of a choice/act of power. Thus, the BNCC doubts its own legitimacy in the current social-political-economic context. The objective of this training meeting was to discuss, with the undergraduate students, through texts and videos, the contingencies and flows of the BNCC, defending the idea of a curriculum policy without foundation to be able, from there, to think about possibilities of other curricula, less hegemonic, normatized, unequal, excluding, assisted by the idea of minor education. The result of such a discussion crystallized in the activity of writing and rewriting a cloud of words throughout the formation, in which the Base went from a set of statements to a set of uncertainties and questions.ResumoO texto propõe relatar uma experiência de formação docente junto ao Proesde/Licenciatura (Programa de Educação Superior para o Desenvolvimento Regional do Estado de Santa Catarina), vinculado à Universidade Regional de Blumenau – FURB. No ano 2018, tal programa buscou qualificar os estudantes de licenciatura para atuarem frente à BNCC (Base Nacional Comum Curricular), configurada como sendo uma política pública de padronização do currículo nacional. Dentro do programa previsto de formação, foi proporcionado um encontro que percorresse outros fluxos do até então instituído e discursado sobre a BNCC, problematizando o currículo através do viés epistemológico pós-crítico, que o interpreta como sendo um campo de disputas pela significação do que vem a ser currículo e como ele deve operar na instituição escolar. Essa perspectiva entende que as decisões políticas são determinadas por discursos de verdade que cristalizam normas comuns e totalitárias que merecem ser questionadas, fazendo emergir os antagonismos daquilo que foi sedimentado em decorrência de uma escolha/ato de poder. Assim, a BNCC coloca em dúvida sua própria legitimidade no contexto social-político-econômico atual. Objetivou-se nesse encontro de formação discutir, junto aos licenciandos, através de textos e vídeos, as contingências e os fluxos da BNCC, defendendo a ideia de uma política curricular sem fundamentos para poder, a partir daí, pensar possibilidades de currículos-outros, menos hegemônicos, normatizados, desiguais, excludentes, assistidos pela ideia de educação menor. O resultado proveniente de tal discussão cristalizou-se na atividade de escrita e reescrita de uma nuvem de palavras ao longo da formação, na qual a Base passou de um conjunto de afirmações para um conjunto de incertezas e interrogações.Palavras-chave: BNCC, Currículo, Formação docente, Políticas educacionais.Keywords: Curriculum, Teacher training, Educational policies.ReferencesA LINGUA das mariposas (La lengua de las mariposas, original). Direção: José Luis Cuerda. Elenco: Manuel Lozano, Fernando Fernán Gómez, Uxía Blanco, outros. Roteiro: José Luis Cuerda, Manuel Rivas, Rafael Azcona. Produção: Canal+ España. Espanha, 1999 (drama, 96 min).AGUIAR, Marcia Angela da S.; DOURADO, Luiz Fernandes. (orgs.). A BNCC na contramão do PNE 2014-2014: avaliação e perspectivas. [Livro Eletrônico]. – Recife: ANPAE, 2018.APPLE, Michael W. Reestruturação Educativa e Curricular e as Agendas Neoliberal e Neoconservadora: Entrevista com Michael Apple. Currículo sem Fronteiras, v.1, n.1, pp.5-33, jan./jun. 2001.BRASIL. LEI Nº 9.394, de 20 de dezembro de 1996. Estabelece as diretrizes e bases da educação nacional. Diário Oficial da União: Brasília, 1996; 175º da Independência e 108º da República.DELEUZE, Gilles. Conversações. Tradução de Peter Pál Pelbart. São Paulo: Editora 34, 2013.DELEUZE, Gilles; GUATARRI, Félix. Kafka: por uma literatura menor. Tradução Cintia Vieira da Silva. Belo Horizonte: Editora Autêntica, 2015.FOUCAULT, Michel. Vigiar e Punir: Nascimento da Prisão; tradução de Raquel Ramalhete. 38. Ed. Petrópolis, RJ: Vozes, 2010.GALLO, Sílvio. Deleuze & a Educação. 3. ed. Belo Horizonte: Autêntica Editora, 2013.LOPES, Alice Casemiro. Por um currículo sem fundamentos. Linhas Críticas, v. 21, n. 45, 2015.NEGRI, Antoni. Exílio. São Paulo: Iluminuras, 2001.QUINTANA, Mario. Caderno H. Rio de Janeiro: Objetiva, 2013.SILVA, Tomaz Tadeu da. Documentos de identidade: uma introdução as teorias de currículo. 3 ed. Belo Horizonte: Autêntica Editora, 2013.TODESCHINI, Raquel Terezinha. (org.). BNCC da Educação Infantil e Ensino Fundamental segundo a análise dos profissionais da educação pública de Santa Catarina. UNIEDU: Programa de Bolsas Universitárias de Santa Catarina. Estado de Santa Catarina, Secretaria de Estado da Educação, Diretoria de Políticas e Planejamento Educacional, 2018.VARELA, Julia; ALVAREZ-URÍA, Fernando. A Maquinaria escolar. Teoria & Educação. São Paulo, n. 6, p.68-96, 1992.11'9"01 September 11. Filme composto de 11 curtas-metragens. Direção e Roteiro: Youssef Chahine, Amos Gitaï, Alejandro González Iñárritu, Shohei Imamura, Claude Lelouch, Ken Loach, Samira Makhmalbaf, Mira Nair, Idrissa Ouedraogo, Sean Penn, Danis Tanovic. Produção: Alain Brigand. França, Estados Unidos, México, Irã, outros, 2002 (drama, 134 min).e3924129
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Helmholz, P., S. Zlatanova, J. Barton, and M. Aleksandrov. "GEOINFORMATION FOR DISASTER MANAGEMENT 2020 (Gi4DM2020): PREFACE." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLIV-3/W1-2020 (November 18, 2020): 1–3. http://dx.doi.org/10.5194/isprs-archives-xliv-3-w1-2020-1-2020.

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Abstract. Across the world, nature-triggered disasters fuelled by climate change are worsening. Some two billion people have been affected by the consequences of natural hazards over the last ten years, 95% of which were weather-related (such as floods and windstorms). Fires swept across large parts of California, and in Australia caused unprecedented destruction to lives, wildlife and bush. This picture is likely to become the new normal, and indeed may worsen if unchecked. The Intergovernmental Panel on Climate Change (IPCC) estimates that in some locations, disaster that once had a once-in-a-century frequency may become annual events by 2050.Disaster management needs to keep up. Good cooperation and coordination of crisis response operations are of critical importance to react rapidly and adequately to any crisis situation, while post-disaster recovery presents opportunities to build resilience towards reducing the scale of the next disaster. Technology to support crisis response has advanced greatly in the last few years. Systems for early warning, command and control and decision-making have been successfully implemented in many countries and regions all over the world. Efforts to improve humanitarian response, in particular in relation to combating disasters in rapidly urbanising cities, have also led to better approaches that grapple with complexity and uncertainty.The challenges however are daunting. Many aspects related to the efficient collection and integration of geo-information, applied semantics and situational awareness for disaster management are still open, while agencies, organisations and governmental authorities need to improve their practices for building better resilience.Gi4DM 2020 marked the 13th edition of the Geoinformation for Disaster Management series of conferences. The first conference was held in 2005 in the aftermath of the 2004 Indian Ocean earthquake and tsunami which claimed the lives of over 220,000 civilians. The 2019-20 Australian Bushfire Season saw some 18.6 million Ha of bushland burn, 5,900 buildings destroyed and nearly three billion vertebrates killed. Gi4DM 2020 then was held during Covid-19 pandemic, which took the lives of more than 1,150,000 people by the time of the conference. The pandemic affected the organisation of the conference, but the situation also provided the opportunity to address important global problems.The fundamental goal of the Gi4DM has always been to provide a forum where emergency responders, disaster managers, urban planners, stakeholders, researchers, data providers and system developers can discuss challenges, share experience, discuss new ideas and demonstrate technology. The 12 previous editions of Gi4DM conferences were held in Delft, the Netherlands (March 2005), Goa, India (September 2006), Toronto, Canada (May 2007), Harbin, China (August 2008), Prague, Czech Republic (January 2009), Torino, Italy (February 2010), Antalya, Turkey (May 2011), Enschede, the Netherlands (December, 2012), Hanoi, Vietnam (December 2013), Montpellier, France (2015), Istanbul, Turkey (2018) and Prague, Czech Republic (2019). Through the years Gi4DM has been organised in cooperation with different international bodies such as ISPRS, UNOOSA, ICA, ISCRAM, FIG, IAG, OGC and WFP and supported by national organisations.Gi4DM 2020 was held as part of Climate Change and Disaster Management: Technology and Resilience for a Troubled World. The event took place through the whole week of 30th of November to 4th of December, Sydney, Australia and included three events: Gi4DM 2020, NSW Surveying and Spatial Sciences Institute (NSW SSSI) annual meeting and Urban Resilience Asia Pacific 2 (URAP2).The event explored two interlinked aspects of disaster management in relation to climate change. The first was geo-information technologies and their application for work in crisis situations, as well as sensor and communication networks and their roles for improving situational awareness. The second aspect was resilience, and its role and purpose across the entire cycle of disaster management, from pre-disaster preparedness to post-disaster recovery including challenges and opportunities in relation to rapid urbanisation and the role of security in improved disaster management practices.This volume consists of 22 scientific papers. These were selected on the basis of double-blind review from among the 40 short papers submitted to the Gi4DM 2020 conference. Each paper was reviewed by two scientific reviewers. The authors of the papers were encouraged to revise, extend and adapt their papers to reflect the comments of the reviewers and fit the goals of this volume. The selected papers concentrate on monitoring and analysis of various aspects related to Covid-19 (4), emergency response (4), earthquakes (3), flood (2), forest fire, landslides, glaciers, drought, land cover change, crop management, surface temperature, address standardisation and education for disaster management. The presented methods range from remote sensing, LiDAR and photogrammetry on different platforms to GIS and Web-based technologies. Figure 1 illustrates the covered topics via wordcount of keywords and titles.The Gi4DM 2020 program consisted of scientific presentations, keynote speeches, panel discussions and tutorials. The four keynotes speakers Prof Suzan Cutter (Hazard and Vulnerability Research Institute, USC, US), Jeremy Fewtrell (NSW Fire and Rescue, Australia), Prof Orhan Altan (Ad-hoc Committee on RISK and Disaster Management, GeoUnions, Turkey) and Prof Philip Gibbins (Fenner School of Environment and Society, ANU, Australia) concentrated on different aspects of disaster and risk management in the context of climate change. Eight tutorials offered exciting workshops and hands-on on: Semantic web tools and technologies within Disaster Management, Structure-from-motion photogrammetry, Radar Remote Sensing, Dam safety: Monitoring subsidence with SAR Interferometry, Location-based Augmented Reality apps with Unity and Mapbox, Visualising bush fires datasets using open source, Making data smarter to manage disasters and emergency situational awareness and Response using HERE Location Services. The scientific sessions were blended with panel discussions to provide more opportunities to exchange ideas and experiences, connect people and researchers from all over the world.The editors of this volume acknowledge all members of the scientific committee for their time, careful review and valuable comments: Abdoulaye Diakité (Australia), Alexander Rudloff (Germany), Alias Abdul Rahman (Malaysia), Alper Yilmaz (USA), Amy Parker (Australia), Ashraf Dewan (Australia), Bapon Shm Fakhruddin (New Zealand), Batuhan Osmanoglu (USA), Ben Gorte (Australia), Bo Huang (Hong Kong), Brendon McAtee (Australia), Brian Lee (Australia), Bruce Forster (Australia), Charity Mundava (Australia), Charles Toth (USA), Chris Bellman (Australia), Chris Pettit (Australia), Clive Fraser (Australia), Craig Glennie (USA), David Belton (Australia), Dev Raj Paudyal (Australia), Dimitri Bulatov (Germany), Dipak Paudyal (Australia), Dorota Iwaszczuk (Germany), Edward Verbree (The Netherlands), Eliseo Clementini (Italy), Fabio Giulio Tonolo (Italy), Fazlay Faruque (USA), Filip Biljecki (Singapore), Petra Helmholz (Australia), Francesco Nex (The Netherlands), Franz Rottensteiner (Germany), George Sithole (South Africa), Graciela Metternicht (Australia), Haigang Sui (China), Hans-Gerd Maas (Germany), Hao Wu (China), Huayi Wu (China), Ivana Ivanova (Australia), Iyyanki Murali Krishna (India), Jack Barton (Australia), Jagannath Aryal (Australia), Jie Jiang (China), Joep Compvoets (Belgium), Jonathan Li (Canada), Kourosh Khoshelham (Australia), Krzysztof Bakuła (Poland), Lars Bodum (Denmark), Lena Halounova (Czech Republic), Madhu Chandra (Germany), Maria Antonia Brovelli (Italy), Martin Breunig (Germany), Martin Tomko (Australia), Mila Koeva (The Netherlands), Mingshu Wang (The Netherlands), Mitko Aleksandrov (Australia), Mulhim Al Doori (UAE), Nancy Glenn (Australia), Negin Nazarian (Australia), Norbert Pfeifer (Austria), Norman Kerle (The Netherlands), Orhan Altan (Turkey), Ori Gudes (Australia), Pawel Boguslawski (Poland), Peter van Oosterom (The Netherlands), Petr Kubíček (Czech Republic), Petros Patias (Greece), Piero Boccardo (Italy), Qiaoli Wu (China), Qing Zhu (China), Riza Yosia Sunindijo (Australia), Roland Billen (Belgium), Rudi Stouffs (Singapore), Scott Hawken (Australia), Serene Coetzee (South Africa), Shawn Laffan (Australia), Shisong Cao (China), Sisi Zlatanova (Australia), Songnian Li (Canada), Stephan Winter (Australia), Tarun Ghawana (Australia), Ümit Işıkdağ (Turkey), Wei Li (Australia), Wolfgang Reinhardt (Germany), Xianlian Liang (Finland) and Yanan Liu (China).The editors would like to express their gratitude to all contributors, who made this volume possible. Many thanks go to all supporting organisations: ISPRS, SSSI, URAP2, Blackash, Mercury and ISPRS Journal of Geoinformation. The editors are grateful to the continued support of the involved Universities: The University of New South Wales, Curtin University, Australian National University and The University of Melbourne.
27

Helmholz, P., S. Zlatanova, J. Barton, and M. Aleksandrov. "GEOINFORMATION FOR DISASTER MANAGEMENT 2020 (GI4DM2020): PREFACE." ISPRS Annals of Photogrammetry, Remote Sensing and Spatial Information Sciences VI-3/W1-2020 (November 17, 2020): 1–2. http://dx.doi.org/10.5194/isprs-annals-vi-3-w1-2020-1-2020.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
Анотація:
Abstract. Across the world, nature-triggered disasters fuelled by climate change are worsening. Some two billion people have been affected by the consequences of natural hazards over the last ten years, 95% of which were weather-related (such as floods and windstorms). Fires swept across large parts of California, and in Australia caused unprecedented destruction to lives, wildlife and bush. This picture is likely to become the new normal, and indeed may worsen if unchecked. The Intergovernmental Panel on Climate Change (IPCC) estimates that in some locations, disaster that once had a once-in-a-century frequency may become annual events by 2050.Disaster management needs to keep up. Good cooperation and coordination of crisis response operations are of critical importance to react rapidly and adequately to any crisis situation, while post-disaster recovery presents opportunities to build resilience towards reducing the scale of the next disaster. Technology to support crisis response has advanced greatly in the last few years. Systems for early warning, command and control and decision-making have been successfully implemented in many countries and regions all over the world. Efforts to improve humanitarian response, in particular in relation to combating disasters in rapidly urbanising cities, have also led to better approaches that grapple with complexity and uncertainty.The challenges however are daunting. Many aspects related to the efficient collection and integration of geo-information, applied semantics and situational awareness for disaster management are still open, while agencies, organisations and governmental authorities need to improve their practices for building better resilience.Gi4DM 2020 marked the 13th edition of the Geoinformation for Disaster Management series of conferences. The first conference was held in 2005 in the aftermath of the 2004 Indian Ocean earthquake and tsunami which claimed the lives of over 220,000 civilians. The 2019-20 Australian Bushfire Season saw some 18.6 million Ha of bushland burn, 5,900 buildings destroyed and nearly three billion vertebrates killed. Gi4DM 2020 then was held during Covid-19 pandemic, which took the lives of more than 1,150,000 people by the time of the conference. The pandemic affected the organisation of the conference, but the situation also provided the opportunity to address important global problems.The fundamental goal of the Gi4DM has always been to provide a forum where emergency responders, disaster managers, urban planners, stakeholders, researchers, data providers and system developers can discuss challenges, share experience, discuss new ideas and demonstrate technology. The 12 previous editions of Gi4DM conferences were held in Delft, the Netherlands (March 2005), Goa, India (September 2006), Toronto, Canada (May 2007), Harbin, China (August 2008), Prague, Czech Republic (January 2009), Torino, Italy (February 2010), Antalya, Turkey (May 2011), Enschede, the Netherlands (December, 2012), Hanoi, Vietnam (December 2013), Montpellier, France (2015), Istanbul, Turkey (2018) and Prague, Czech Republic (2019). Through the years Gi4DM has been organised in cooperation with different international bodies such as ISPRS, UNOOSA, ICA, ISCRAM, FIG, IAG, OGC and WFP and supported by national organisations.Gi4DM 2020 was held as part of Climate Change and Disaster Management: Technology and Resilience for a Troubled World. The event took place through the whole week of 30th of November to 4th of December, Sydney, Australia and included three events: Gi4DM 2020, NSW Surveying and Spatial Sciences Institute (NSW SSSI) annual meeting and Urban Resilience Asia Pacific 2 (URAP2).The event explored two interlinked aspects of disaster management in relation to climate change. The first was geo-information technologies and their application for work in crisis situations, as well as sensor and communication networks and their roles for improving situational awareness. The second aspect was resilience, and its role and purpose across the entire cycle of disaster management, from pre-disaster preparedness to post-disaster recovery including challenges and opportunities in relation to rapid urbanisation and the role of security in improved disaster management practices.This volume consists of 16 peer-reviewed scientific papers. These were selected on the basis of double-blind review from among the 25 full papers submitted to the Gi4DM 2020 conference. Each paper was reviewed by three scientific reviewers. The authors of the papers were encouraged to revise, extend and adapt their papers to reflect the comments of the reviewers and fit the goals of this volume. The selected papers concentrate on monitoring and analysis of forest fire (3), landslides (3), flood (2), earthquake, avalanches, water pollution, heat, evacuation and urban sustainability, applying a variety of remote sensing, GIS and Web-based technologies. Figure 1 illustrates the scope of the covered topics though the word count of keywords and titles.The Gi4DM 2020 program consisted of scientific presentations, keynote speeches, panel discussions and tutorials. The four keynotes speakers Prof Suzan Cutter (Hazard and Vulnerability Research Institute, USC, US), Jeremy Fewtrell (NSW Fire and Rescue, Australia), Prof Orhan Altan (Ad-hoc Committee on RISK and Disaster Management, GeoUnions, Turkey) and Prof Philip Gibbins (Fenner School of Environment and Society, ANU, Australia) concentrated on different aspects of disaster and risk management in the context of climate change. Eight tutorials offered exciting workshops and hands-on on: Semantic web tools and technologies within Disaster Management, Structure-from-motion photogrammetry, Radar Remote Sensing, Dam safety: Monitoring subsidence with SAR Interferometry, Location-based Augmented Reality apps with Unity and Mapbox, Visualising bush fires datasets using open source, Making data smarter to manage disasters and emergency situational awareness and Response using HERE Location Services. The scientific sessions were blended with panel discussions to provide more opportunities to exchange ideas and experiences, connect people and researchers from all over the world.The editors of this volume acknowledge all members of the scientific committee for their time, careful review and valuable comments: Abdoulaye Diakité (Australia), Alexander Rudloff (Germany), Alias Abdul Rahman (Malaysia), Alper Yilmaz (USA), Amy Parker (Australia), Ashraf Dewan (Australia), Bapon Shm Fakhruddin (New Zealand), Batuhan Osmanoglu (USA), Ben Gorte (Australia), Bo Huang (Hong Kong), Brendon McAtee (Australia), Brian Lee (Australia), Bruce Forster (Australia), Charity Mundava (Australia), Charles Toth (USA), Chris Bellman (Australia), Chris Pettit (Australia), Clive Fraser (Australia), Craig Glennie (USA), David Belton (Australia), Dev Raj Paudyal (Australia), Dimitri Bulatov (Germany), Dipak Paudyal (Australia), Dorota Iwaszczuk (Germany), Edward Verbree (The Netherlands), Eliseo Clementini (Italy), Fabio Giulio Tonolo (Italy), Fazlay Faruque (USA), Filip Biljecki (Singapore), Petra Helmholz (Australia), Francesco Nex (The Netherlands), Franz Rottensteiner (Germany), George Sithole (South Africa), Graciela Metternicht (Australia), Haigang Sui (China), Hans-Gerd Maas (Germany), Hao Wu (China), Huayi Wu (China), Ivana Ivanova (Australia), Iyyanki Murali Krishna (India), Jack Barton (Australia), Jagannath Aryal (Australia), Jie Jiang (China), Joep Compvoets (Belgium), Jonathan Li (Canada), Kourosh Khoshelham (Australia), Krzysztof Bakuła (Poland), Lars Bodum (Denmark), Lena Halounova (Czech Republic), Madhu Chandra (Germany), Maria Antonia Brovelli (Italy), Martin Breunig (Germany), Martin Tomko (Australia), Mila Koeva (The Netherlands), Mingshu Wang (The Netherlands), Mitko Aleksandrov (Australia), Mulhim Al Doori (UAE), Nancy Glenn (Australia), Negin Nazarian (Australia), Norbert Pfeifer (Austria), Norman Kerle (The Netherlands), Orhan Altan (Turkey), Ori Gudes (Australia), Pawel Boguslawski (Poland), Peter van Oosterom (The Netherlands), Petr Kubíček (Czech Republic), Petros Patias (Greece), Piero Boccardo (Italy), Qiaoli Wu (China), Qing Zhu (China), Riza Yosia Sunindijo (Australia), Roland Billen (Belgium), Rudi Stouffs (Singapore), Scott Hawken (Australia), Serene Coetzee (South Africa), Shawn Laffan (Australia), Shisong Cao (China), Sisi Zlatanova (Australia), Songnian Li (Canada), Stephan Winter (Australia), Tarun Ghawana (Australia), Ümit Işıkdağ (Turkey), Wei Li (Australia), Wolfgang Reinhardt (Germany), Xianlian Liang (Finland) and Yanan Liu (China).The editors would like to express their gratitude to all contributors, who made this volume possible. Many thanks go to all supporting organisations: ISPRS, SSSI, URAP2, Blackash, Mercury and ISPRS Journal of Geoinformation. The editors are grateful to the continued support of the involved Universities: The University of New South Wales, Curtin University, Australian National University and The University of Melbourne.
28

Abdelhedi, Fatma, and Nabil Derbel. "Volume 2, Issue 3, Special issue on Recent Advances in Engineering Systems (Published Papers) Articles Transmit / Received Beamforming for Frequency Diverse Array with Symmetrical frequency offsets Shaddrack Yaw Nusenu Adv. Sci. Technol. Eng. Syst. J. 2(3), 1-6 (2017); View Description Detailed Analysis of Amplitude and Slope Diffraction Coefficients for knife-edge structure in S-UTD-CH Model Eray Arik, Mehmet Baris Tabakcioglu Adv. Sci. Technol. Eng. Syst. J. 2(3), 7-11 (2017); View Description Applications of Case Based Organizational Memory Supported by the PAbMM Architecture Martín, María de los Ángeles, Diván, Mario José Adv. Sci. Technol. Eng. Syst. J. 2(3), 12-23 (2017); View Description Low Probability of Interception Beampattern Using Frequency Diverse Array Antenna Shaddrack Yaw Nusenu Adv. Sci. Technol. Eng. Syst. J. 2(3), 24-29 (2017); View Description Zero Trust Cloud Networks using Transport Access Control and High Availability Optical Bypass Switching Casimer DeCusatis, Piradon Liengtiraphan, Anthony Sager Adv. Sci. Technol. Eng. Syst. J. 2(3), 30-35 (2017); View Description A Derived Metrics as a Measurement to Support Efficient Requirements Analysis and Release Management Indranil Nath Adv. Sci. Technol. Eng. Syst. J. 2(3), 36-40 (2017); View Description Feedback device of temperature sensation for a myoelectric prosthetic hand Yuki Ueda, Chiharu Ishii Adv. Sci. Technol. Eng. Syst. J. 2(3), 41-40 (2017); View Description Deep venous thrombus characterization: ultrasonography, elastography and scattering operator Thibaud Berthomier, Ali Mansour, Luc Bressollette, Frédéric Le Roy, Dominique Mottier Adv. Sci. Technol. Eng. Syst. J. 2(3), 48-59 (2017); View Description Improving customs’ border control by creating a reference database of cargo inspection X-ray images Selina Kolokytha, Alexander Flisch, Thomas Lüthi, Mathieu Plamondon, Adrian Schwaninger, Wicher Vasser, Diana Hardmeier, Marius Costin, Caroline Vienne, Frank Sukowski, Ulf Hassler, Irène Dorion, Najib Gadi, Serge Maitrejean, Abraham Marciano, Andrea Canonica, Eric Rochat, Ger Koomen, Micha Slegt Adv. Sci. Technol. Eng. Syst. J. 2(3), 60-66 (2017); View Description Aviation Navigation with Use of Polarimetric Technologies Arsen Klochan, Ali Al-Ammouri, Viktor Romanenko, Vladimir Tronko Adv. Sci. Technol. Eng. Syst. J. 2(3), 67-72 (2017); View Description Optimization of Multi-standard Transmitter Architecture Using Single-Double Conversion Technique Used for Rescue Operations Riadh Essaadali, Said Aliouane, Chokri Jebali and Ammar Kouki Adv. Sci. Technol. Eng. Syst. J. 2(3), 73-81 (2017); View Description Singular Integral Equations in Electromagnetic Waves Reflection Modeling A. S. Ilinskiy, T. N. Galishnikova Adv. Sci. Technol. Eng. Syst. J. 2(3), 82-87 (2017); View Description Methodology for Management of Information Security in Industrial Control Systems: A Proof of Concept aligned with Enterprise Objectives. Fabian Bustamante, Walter Fuertes, Paul Diaz, Theofilos Toulqueridis Adv. Sci. Technol. Eng. Syst. J. 2(3), 88-99 (2017); View Description Dependence-Based Segmentation Approach for Detecting Morpheme Boundaries Ahmed Khorsi, Abeer Alsheddi Adv. Sci. Technol. Eng. Syst. J. 2(3), 100-110 (2017); View Description Paper Improving Rule Based Stemmers to Solve Some Special Cases of Arabic Language Soufiane Farrah, Hanane El Manssouri, Ziyati Elhoussaine, Mohamed Ouzzif Adv. Sci. Technol. Eng. Syst. J. 2(3), 111-115 (2017); View Description Medical imbalanced data classification Sara Belarouci, Mohammed Amine Chikh Adv. Sci. Technol. Eng. Syst. J. 2(3), 116-124 (2017); View Description ADOxx Modelling Method Conceptualization Environment Nesat Efendioglu, Robert Woitsch, Wilfrid Utz, Damiano Falcioni Adv. Sci. Technol. Eng. Syst. J. 2(3), 125-136 (2017); View Description GPSR+Predict: An Enhancement for GPSR to Make Smart Routing Decision by Anticipating Movement of Vehicles in VANETs Zineb Squalli Houssaini, Imane Zaimi, Mohammed Oumsis, Saïd El Alaoui Ouatik Adv. Sci. Technol. Eng. Syst. J. 2(3), 137-146 (2017); View Description Optimal Synthesis of Universal Space Vector Digital Algorithm for Matrix Converters Adrian Popovici, Mircea Băbăiţă, Petru Papazian Adv. Sci. Technol. Eng. Syst. J. 2(3), 147-152 (2017); View Description Control design for axial flux permanent magnet synchronous motor which operates above the nominal speed Xuan Minh Tran, Nhu Hien Nguyen, Quoc Tuan Duong Adv. Sci. Technol. Eng. Syst. J. 2(3), 153-159 (2017); View Description A synchronizing second order sliding mode control applied to decentralized time delayed multi−agent robotic systems: Stability Proof Marwa Fathallah, Fatma Abdelhedi, Nabil Derbel Adv. Sci. Technol. Eng. Syst. J. 2(3), 160-170 (2017); View Description Fault Diagnosis and Tolerant Control Using Observer Banks Applied to Continuous Stirred Tank Reactor Martin F. Pico, Eduardo J. Adam Adv. Sci. Technol. Eng. Syst. J. 2(3), 171-181 (2017); View Description Development and Validation of a Heat Pump System Model Using Artificial Neural Network Nabil Nassif, Jordan Gooden Adv. Sci. Technol. Eng. Syst. J. 2(3), 182-185 (2017); View Description Assessment of the usefulness and appeal of stigma-stop by psychology students: a serious game designed to reduce the stigma of mental illness Adolfo J. Cangas, Noelia Navarro, Juan J. Ojeda, Diego Cangas, Jose A. Piedra, José Gallego Adv. Sci. Technol. Eng. Syst. J. 2(3), 186-190 (2017); View Description Kinect-Based Moving Human Tracking System with Obstacle Avoidance Abdel Mehsen Ahmad, Zouhair Bazzal, Hiba Al Youssef Adv. Sci. Technol. Eng. Syst. J. 2(3), 191-197 (2017); View Description A security approach based on honeypots: Protecting Online Social network from malicious profiles Fatna Elmendili, Nisrine Maqran, Younes El Bouzekri El Idrissi, Habiba Chaoui Adv. Sci. Technol. Eng. Syst. J. 2(3), 198-204 (2017); View Description Pulse Generator for Ultrasonic Piezoelectric Transducer Arrays Based on a Programmable System-on-Chip (PSoC) Pedro Acevedo, Martín Fuentes, Joel Durán, Mónica Vázquez, Carlos Díaz Adv. Sci. Technol. Eng. Syst. J. 2(3), 205-209 (2017); View Description Enabling Toy Vehicles Interaction With Visible Light Communication (VLC) M. A. Ilyas, M. B. Othman, S. M. Shah, Mas Fawzi Adv. Sci. Technol. Eng. Syst. J. 2(3), 210-216 (2017); View Description Analysis of Fractional-Order 2xn RLC Networks by Transmission Matrices Mahmut Ün, Manolya Ün Adv. Sci. Technol. Eng. Syst. J. 2(3), 217-220 (2017); View Description Fire extinguishing system in large underground garages Ivan Antonov, Rositsa Velichkova, Svetlin Antonov, Kamen Grozdanov, Milka Uzunova, Ikram El Abbassi Adv. Sci. Technol. Eng. Syst. J. 2(3), 221-226 (2017); View Description Directional Antenna Modulation Technique using A Two-Element Frequency Diverse Array Shaddrack Yaw Nusenu Adv. Sci. Technol. Eng. Syst. J. 2(3), 227-232 (2017); View Description Classifying region of interests from mammograms with breast cancer into BIRADS using Artificial Neural Networks Estefanía D. Avalos-Rivera, Alberto de J. Pastrana-Palma Adv. Sci. Technol. Eng. Syst. J. 2(3), 233-240 (2017); View Description Magnetically Levitated and Guided Systems Florian Puci, Miroslav Husak Adv. Sci. Technol. Eng. Syst. J. 2(3), 241-244 (2017); View Description Energy-Efficient Mobile Sensing in Distributed Multi-Agent Sensor Networks Minh T. Nguyen Adv. Sci. Technol. Eng. Syst. J. 2(3), 245-253 (2017); View Description Validity and efficiency of conformal anomaly detection on big distributed data Ilia Nouretdinov Adv. Sci. Technol. Eng. Syst. J. 2(3), 254-267 (2017); View Description S-Parameters Optimization in both Segmented and Unsegmented Insulated TSV upto 40GHz Frequency Juma Mary Atieno, Xuliang Zhang, HE Song Bai Adv. Sci. Technol. Eng. Syst. J. 2(3), 268-276 (2017); View Description Synthesis of Important Design Criteria for Future Vehicle Electric System Lisa Braun, Eric Sax Adv. Sci. Technol. Eng. Syst. J. 2(3), 277-283 (2017); View Description Gestural Interaction for Virtual Reality Environments through Data Gloves G. Rodriguez, N. Jofre, Y. Alvarado, J. Fernández, R. Guerrero Adv. Sci. Technol. Eng. Syst. J. 2(3), 284-290 (2017); View Description Solving the Capacitated Network Design Problem in Two Steps Meriem Khelifi, Mohand Yazid Saidi, Saadi Boudjit Adv. Sci. Technol. Eng. Syst. J. 2(3), 291-301 (2017); View Description A Computationally Intelligent Approach to the Detection of Wormhole Attacks in Wireless Sensor Networks Mohammad Nurul Afsar Shaon, Ken Ferens Adv. Sci. Technol. Eng. Syst. J. 2(3), 302-320 (2017); View Description Real Time Advanced Clustering System Giuseppe Spampinato, Arcangelo Ranieri Bruna, Salvatore Curti, Viviana D’Alto Adv. Sci. Technol. Eng. Syst. J. 2(3), 321-326 (2017); View Description Indoor Mobile Robot Navigation in Unknown Environment Using Fuzzy Logic Based Behaviors Khalid Al-Mutib, Foudil Abdessemed Adv. Sci. Technol. Eng. Syst. J. 2(3), 327-337 (2017); View Description Validity of Mind Monitoring System as a Mental Health Indicator using Voice Naoki Hagiwara, Yasuhiro Omiya, Shuji Shinohara, Mitsuteru Nakamura, Masakazu Higuchi, Shunji Mitsuyoshi, Hideo Yasunaga, Shinichi Tokuno Adv. Sci. Technol. Eng. Syst. J. 2(3), 338-344 (2017); View Description The Model of Adaptive Learning Objects for virtual environments instanced by the competencies Carlos Guevara, Jose Aguilar, Alexandra González-Eras Adv. Sci. Technol. Eng. Syst. J. 2(3), 345-355 (2017); View Description An Overview of Traceability: Towards a general multi-domain model Kamal Souali, Othmane Rahmaoui, Mohammed Ouzzif Adv. Sci. Technol. Eng. Syst. J. 2(3), 356-361 (2017); View Description L-Band SiGe HBT Active Differential Equalizers with Variable, Positive or Negative Gain Slopes Using Dual-Resonant RLC Circuits Yasushi Itoh, Hiroaki Takagi Adv. Sci. Technol. Eng. Syst. J. 2(3), 362-368 (2017); View Description Moving Towards Reliability-Centred Management of Energy, Power and Transportation Assets Kang Seng Seow, Loc K. Nguyen, Kelvin Tan, Kees-Jan Van Oeveren Adv. Sci. Technol. Eng. Syst. J. 2(3), 369-375 (2017); View Description Secure Path Selection under Random Fading Furqan Jameel, Faisal, M Asif Ali Haider, Amir Aziz Butt Adv. Sci. Technol. Eng. Syst. J. 2(3), 376-383 (2017); View Description Security in SWIPT with Power Splitting Eavesdropper Furqan Jameel, Faisal, M Asif Ali Haider, Amir Aziz Butt Adv. Sci. Technol. Eng. Syst. J. 2(3), 384-388 (2017); View Description Performance Analysis of Phased Array and Frequency Diverse Array Radar Ambiguity Functions Shaddrack Yaw Nusenu Adv. Sci. Technol. Eng. Syst. J. 2(3), 389-394 (2017); View Description Adaptive Discrete-time Fuzzy Sliding Mode Control For a Class of Chaotic Systems Hanene Medhaffar, Moez Feki, Nabil Derbel Adv. Sci. Technol. Eng. Syst. J. 2(3), 395-400 (2017); View Description Fault Tolerant Inverter Topology for the Sustainable Drive of an Electrical Helicopter Igor Bolvashenkov, Jörg Kammermann, Taha Lahlou, Hans-Georg Herzog Adv. Sci. Technol. Eng. Syst. J. 2(3), 401-411 (2017); View Description Computational Intelligence Methods for Identifying Voltage Sag in Smart Grid Turgay Yalcin, Muammer Ozdemir Adv. Sci. Technol. Eng. Syst. J. 2(3), 412-419 (2017); View Description A Highly-Secured Arithmetic Hiding cum Look-Up Table (AHLUT) based S-Box for AES-128 Implementation Ali Akbar Pammu, Kwen-Siong Chong, Bah-Hwee Gwee Adv. Sci. Technol. Eng. Syst. J. 2(3), 420-426 (2017); View Description Service Productivity and Complexity in Medical Rescue Services Markus Harlacher, Andreas Petz, Philipp Przybysz, Olivia Chaillié, Susanne Mütze-Niewöhner Adv. Sci. Technol. Eng. Syst. J. 2(3), 427-434 (2017); View Description Principal Component Analysis Application on Flavonoids Characterization Che Hafizah Che Noh, Nor Fadhillah Mohamed Azmin, Azura Amid Adv. Sci. Technol. Eng. Syst. J. 2(3), 435-440 (2017); View Description A Reconfigurable Metal-Plasma Yagi-Yuda Antenna for Microwave Applications Giulia Mansutti, Davide Melazzi, Antonio-Daniele Capobianco Adv. Sci. Technol. Eng. Syst. J. 2(3), 441-448 (2017); View Description Verifying the Detection Results of Impersonation Attacks in Service Clouds Sarra Alqahtani, Rose Gamble Adv. Sci. Technol. Eng. Syst. J. 2(3), 449-459 (2017); View Description Image Segmentation Using Fuzzy Inference System on YCbCr Color Model Alvaro Anzueto-Rios, Jose Antonio Moreno-Cadenas, Felipe Gómez-Castañeda, Sergio Garduza-Gonzalez Adv. Sci. Technol. Eng. Syst. J. 2(3), 460-468 (2017); View Description Segmented and Detailed Visualization of Anatomical Structures based on Augmented Reality for Health Education and Knowledge Discovery Isabel Cristina Siqueira da Silva, Gerson Klein, Denise Munchen Brandão Adv. Sci. Technol. Eng. Syst. J. 2(3), 469-478 (2017); View Description Intrusion detection in cloud computing based attack patterns and risk assessment Ben Charhi Youssef, Mannane Nada, Bendriss Elmehdi, Regragui Boubker Adv. Sci. Technol. Eng. Syst. J. 2(3), 479-484 (2017); View Description Optimal Sizing and Control Strategy of renewable hybrid systems PV-Diesel Generator-Battery: application to the case of Djanet city of Algeria Adel Yahiaoui, Khelifa Benmansour, Mohamed Tadjine Adv. Sci. Technol. Eng. Syst. J. 2(3), 485-491 (2017); View Description RFID Antenna Near-field Characterization Using a New 3D Magnetic Field Probe Kassem Jomaa, Fabien Ndagijimana, Hussam Ayad, Majida Fadlallah, Jalal Jomaah Adv. Sci. Technol. Eng. Syst. J. 2(3), 492-497 (2017); View Description Design, Fabrication and Testing of a Dual-Range XY Micro-Motion Stage Driven by Voice Coil Actuators Xavier Herpe, Matthew Dunnigan, Xianwen Kong Adv. Sci. Technol. Eng. Syst. J. 2(3), 498-504 (2017); View Description Self-Organizing Map based Feature Learning in Bio-Signal Processing Marwa Farouk Ibrahim Ibrahim, Adel Ali Al-Jumaily Adv. Sci. Technol. Eng. Syst. J. 2(3), 505-512 (2017); View Description A delay-dependent distributed SMC for stabilization of a networked robotic system exposed to external disturbances." Advances in Science, Technology and Engineering Systems Journal 2, no. 3 (June 2016): 513–19. http://dx.doi.org/10.25046/aj020366.

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Biran, Yahav, George Collins, Borky John M, and Joel Dubow. "Volume 2, Issue 3, Special issue on Recent Advances in Engineering Systems (Published Papers) Articles Transmit / Received Beamforming for Frequency Diverse Array with Symmetrical frequency offsets Shaddrack Yaw Nusenu Adv. Sci. Technol. Eng. Syst. J. 2(3), 1-6 (2017); View Description Detailed Analysis of Amplitude and Slope Diffraction Coefficients for knife-edge structure in S-UTD-CH Model Eray Arik, Mehmet Baris Tabakcioglu Adv. Sci. Technol. Eng. Syst. J. 2(3), 7-11 (2017); View Description Applications of Case Based Organizational Memory Supported by the PAbMM Architecture Martín, María de los Ángeles, Diván, Mario José Adv. Sci. Technol. Eng. Syst. J. 2(3), 12-23 (2017); View Description Low Probability of Interception Beampattern Using Frequency Diverse Array Antenna Shaddrack Yaw Nusenu Adv. Sci. Technol. Eng. Syst. J. 2(3), 24-29 (2017); View Description Zero Trust Cloud Networks using Transport Access Control and High Availability Optical Bypass Switching Casimer DeCusatis, Piradon Liengtiraphan, Anthony Sager Adv. Sci. Technol. Eng. Syst. J. 2(3), 30-35 (2017); View Description A Derived Metrics as a Measurement to Support Efficient Requirements Analysis and Release Management Indranil Nath Adv. Sci. Technol. Eng. Syst. J. 2(3), 36-40 (2017); View Description Feedback device of temperature sensation for a myoelectric prosthetic hand Yuki Ueda, Chiharu Ishii Adv. Sci. Technol. Eng. Syst. J. 2(3), 41-40 (2017); View Description Deep venous thrombus characterization: ultrasonography, elastography and scattering operator Thibaud Berthomier, Ali Mansour, Luc Bressollette, Frédéric Le Roy, Dominique Mottier Adv. Sci. Technol. Eng. Syst. J. 2(3), 48-59 (2017); View Description Improving customs’ border control by creating a reference database of cargo inspection X-ray images Selina Kolokytha, Alexander Flisch, Thomas Lüthi, Mathieu Plamondon, Adrian Schwaninger, Wicher Vasser, Diana Hardmeier, Marius Costin, Caroline Vienne, Frank Sukowski, Ulf Hassler, Irène Dorion, Najib Gadi, Serge Maitrejean, Abraham Marciano, Andrea Canonica, Eric Rochat, Ger Koomen, Micha Slegt Adv. Sci. Technol. Eng. Syst. J. 2(3), 60-66 (2017); View Description Aviation Navigation with Use of Polarimetric Technologies Arsen Klochan, Ali Al-Ammouri, Viktor Romanenko, Vladimir Tronko Adv. Sci. Technol. Eng. Syst. J. 2(3), 67-72 (2017); View Description Optimization of Multi-standard Transmitter Architecture Using Single-Double Conversion Technique Used for Rescue Operations Riadh Essaadali, Said Aliouane, Chokri Jebali and Ammar Kouki Adv. Sci. Technol. Eng. Syst. J. 2(3), 73-81 (2017); View Description Singular Integral Equations in Electromagnetic Waves Reflection Modeling A. S. Ilinskiy, T. N. Galishnikova Adv. Sci. Technol. Eng. Syst. J. 2(3), 82-87 (2017); View Description Methodology for Management of Information Security in Industrial Control Systems: A Proof of Concept aligned with Enterprise Objectives. Fabian Bustamante, Walter Fuertes, Paul Diaz, Theofilos Toulqueridis Adv. Sci. Technol. Eng. Syst. J. 2(3), 88-99 (2017); View Description Dependence-Based Segmentation Approach for Detecting Morpheme Boundaries Ahmed Khorsi, Abeer Alsheddi Adv. Sci. Technol. Eng. Syst. J. 2(3), 100-110 (2017); View Description Paper Improving Rule Based Stemmers to Solve Some Special Cases of Arabic Language Soufiane Farrah, Hanane El Manssouri, Ziyati Elhoussaine, Mohamed Ouzzif Adv. Sci. Technol. Eng. Syst. J. 2(3), 111-115 (2017); View Description Medical imbalanced data classification Sara Belarouci, Mohammed Amine Chikh Adv. Sci. Technol. Eng. Syst. J. 2(3), 116-124 (2017); View Description ADOxx Modelling Method Conceptualization Environment Nesat Efendioglu, Robert Woitsch, Wilfrid Utz, Damiano Falcioni Adv. Sci. Technol. Eng. Syst. J. 2(3), 125-136 (2017); View Description GPSR+Predict: An Enhancement for GPSR to Make Smart Routing Decision by Anticipating Movement of Vehicles in VANETs Zineb Squalli Houssaini, Imane Zaimi, Mohammed Oumsis, Saïd El Alaoui Ouatik Adv. Sci. Technol. Eng. Syst. J. 2(3), 137-146 (2017); View Description Optimal Synthesis of Universal Space Vector Digital Algorithm for Matrix Converters Adrian Popovici, Mircea Băbăiţă, Petru Papazian Adv. Sci. Technol. Eng. Syst. J. 2(3), 147-152 (2017); View Description Control design for axial flux permanent magnet synchronous motor which operates above the nominal speed Xuan Minh Tran, Nhu Hien Nguyen, Quoc Tuan Duong Adv. Sci. Technol. Eng. Syst. J. 2(3), 153-159 (2017); View Description A synchronizing second order sliding mode control applied to decentralized time delayed multi−agent robotic systems: Stability Proof Marwa Fathallah, Fatma Abdelhedi, Nabil Derbel Adv. Sci. Technol. Eng. Syst. J. 2(3), 160-170 (2017); View Description Fault Diagnosis and Tolerant Control Using Observer Banks Applied to Continuous Stirred Tank Reactor Martin F. Pico, Eduardo J. Adam Adv. Sci. Technol. Eng. Syst. J. 2(3), 171-181 (2017); View Description Development and Validation of a Heat Pump System Model Using Artificial Neural Network Nabil Nassif, Jordan Gooden Adv. Sci. Technol. Eng. Syst. J. 2(3), 182-185 (2017); View Description Assessment of the usefulness and appeal of stigma-stop by psychology students: a serious game designed to reduce the stigma of mental illness Adolfo J. Cangas, Noelia Navarro, Juan J. Ojeda, Diego Cangas, Jose A. Piedra, José Gallego Adv. Sci. Technol. Eng. Syst. J. 2(3), 186-190 (2017); View Description Kinect-Based Moving Human Tracking System with Obstacle Avoidance Abdel Mehsen Ahmad, Zouhair Bazzal, Hiba Al Youssef Adv. Sci. Technol. Eng. Syst. J. 2(3), 191-197 (2017); View Description A security approach based on honeypots: Protecting Online Social network from malicious profiles Fatna Elmendili, Nisrine Maqran, Younes El Bouzekri El Idrissi, Habiba Chaoui Adv. Sci. Technol. Eng. Syst. J. 2(3), 198-204 (2017); View Description Pulse Generator for Ultrasonic Piezoelectric Transducer Arrays Based on a Programmable System-on-Chip (PSoC) Pedro Acevedo, Martín Fuentes, Joel Durán, Mónica Vázquez, Carlos Díaz Adv. Sci. Technol. Eng. Syst. J. 2(3), 205-209 (2017); View Description Enabling Toy Vehicles Interaction With Visible Light Communication (VLC) M. A. Ilyas, M. B. Othman, S. M. Shah, Mas Fawzi Adv. Sci. Technol. Eng. Syst. J. 2(3), 210-216 (2017); View Description Analysis of Fractional-Order 2xn RLC Networks by Transmission Matrices Mahmut Ün, Manolya Ün Adv. Sci. Technol. Eng. Syst. J. 2(3), 217-220 (2017); View Description Fire extinguishing system in large underground garages Ivan Antonov, Rositsa Velichkova, Svetlin Antonov, Kamen Grozdanov, Milka Uzunova, Ikram El Abbassi Adv. Sci. Technol. Eng. Syst. J. 2(3), 221-226 (2017); View Description Directional Antenna Modulation Technique using A Two-Element Frequency Diverse Array Shaddrack Yaw Nusenu Adv. Sci. Technol. Eng. Syst. J. 2(3), 227-232 (2017); View Description Classifying region of interests from mammograms with breast cancer into BIRADS using Artificial Neural Networks Estefanía D. Avalos-Rivera, Alberto de J. Pastrana-Palma Adv. Sci. Technol. Eng. Syst. J. 2(3), 233-240 (2017); View Description Magnetically Levitated and Guided Systems Florian Puci, Miroslav Husak Adv. Sci. Technol. Eng. Syst. J. 2(3), 241-244 (2017); View Description Energy-Efficient Mobile Sensing in Distributed Multi-Agent Sensor Networks Minh T. Nguyen Adv. Sci. Technol. Eng. Syst. J. 2(3), 245-253 (2017); View Description Validity and efficiency of conformal anomaly detection on big distributed data Ilia Nouretdinov Adv. Sci. Technol. Eng. Syst. J. 2(3), 254-267 (2017); View Description S-Parameters Optimization in both Segmented and Unsegmented Insulated TSV upto 40GHz Frequency Juma Mary Atieno, Xuliang Zhang, HE Song Bai Adv. Sci. Technol. Eng. Syst. J. 2(3), 268-276 (2017); View Description Synthesis of Important Design Criteria for Future Vehicle Electric System Lisa Braun, Eric Sax Adv. Sci. Technol. Eng. Syst. J. 2(3), 277-283 (2017); View Description Gestural Interaction for Virtual Reality Environments through Data Gloves G. Rodriguez, N. Jofre, Y. Alvarado, J. Fernández, R. Guerrero Adv. Sci. Technol. Eng. Syst. J. 2(3), 284-290 (2017); View Description Solving the Capacitated Network Design Problem in Two Steps Meriem Khelifi, Mohand Yazid Saidi, Saadi Boudjit Adv. Sci. Technol. Eng. Syst. J. 2(3), 291-301 (2017); View Description A Computationally Intelligent Approach to the Detection of Wormhole Attacks in Wireless Sensor Networks Mohammad Nurul Afsar Shaon, Ken Ferens Adv. Sci. Technol. Eng. Syst. J. 2(3), 302-320 (2017); View Description Real Time Advanced Clustering System Giuseppe Spampinato, Arcangelo Ranieri Bruna, Salvatore Curti, Viviana D’Alto Adv. Sci. Technol. Eng. Syst. J. 2(3), 321-326 (2017); View Description Indoor Mobile Robot Navigation in Unknown Environment Using Fuzzy Logic Based Behaviors Khalid Al-Mutib, Foudil Abdessemed Adv. Sci. Technol. Eng. Syst. J. 2(3), 327-337 (2017); View Description Validity of Mind Monitoring System as a Mental Health Indicator using Voice Naoki Hagiwara, Yasuhiro Omiya, Shuji Shinohara, Mitsuteru Nakamura, Masakazu Higuchi, Shunji Mitsuyoshi, Hideo Yasunaga, Shinichi Tokuno Adv. Sci. Technol. Eng. Syst. J. 2(3), 338-344 (2017); View Description The Model of Adaptive Learning Objects for virtual environments instanced by the competencies Carlos Guevara, Jose Aguilar, Alexandra González-Eras Adv. Sci. Technol. Eng. Syst. J. 2(3), 345-355 (2017); View Description An Overview of Traceability: Towards a general multi-domain model Kamal Souali, Othmane Rahmaoui, Mohammed Ouzzif Adv. Sci. Technol. Eng. Syst. J. 2(3), 356-361 (2017); View Description L-Band SiGe HBT Active Differential Equalizers with Variable, Positive or Negative Gain Slopes Using Dual-Resonant RLC Circuits Yasushi Itoh, Hiroaki Takagi Adv. Sci. Technol. Eng. Syst. J. 2(3), 362-368 (2017); View Description Moving Towards Reliability-Centred Management of Energy, Power and Transportation Assets Kang Seng Seow, Loc K. Nguyen, Kelvin Tan, Kees-Jan Van Oeveren Adv. Sci. Technol. Eng. Syst. J. 2(3), 369-375 (2017); View Description Secure Path Selection under Random Fading Furqan Jameel, Faisal, M Asif Ali Haider, Amir Aziz Butt Adv. Sci. Technol. Eng. Syst. J. 2(3), 376-383 (2017); View Description Security in SWIPT with Power Splitting Eavesdropper Furqan Jameel, Faisal, M Asif Ali Haider, Amir Aziz Butt Adv. Sci. Technol. Eng. Syst. J. 2(3), 384-388 (2017); View Description Performance Analysis of Phased Array and Frequency Diverse Array Radar Ambiguity Functions Shaddrack Yaw Nusenu Adv. Sci. Technol. Eng. Syst. J. 2(3), 389-394 (2017); View Description Adaptive Discrete-time Fuzzy Sliding Mode Control For a Class of Chaotic Systems Hanene Medhaffar, Moez Feki, Nabil Derbel Adv. Sci. Technol. Eng. Syst. J. 2(3), 395-400 (2017); View Description Fault Tolerant Inverter Topology for the Sustainable Drive of an Electrical Helicopter Igor Bolvashenkov, Jörg Kammermann, Taha Lahlou, Hans-Georg Herzog Adv. Sci. Technol. Eng. Syst. J. 2(3), 401-411 (2017); View Description Computational Intelligence Methods for Identifying Voltage Sag in Smart Grid Turgay Yalcin, Muammer Ozdemir Adv. Sci. Technol. Eng. Syst. J. 2(3), 412-419 (2017); View Description A Highly-Secured Arithmetic Hiding cum Look-Up Table (AHLUT) based S-Box for AES-128 Implementation Ali Akbar Pammu, Kwen-Siong Chong, Bah-Hwee Gwee Adv. Sci. Technol. Eng. Syst. J. 2(3), 420-426 (2017); View Description Service Productivity and Complexity in Medical Rescue Services Markus Harlacher, Andreas Petz, Philipp Przybysz, Olivia Chaillié, Susanne Mütze-Niewöhner Adv. Sci. Technol. Eng. Syst. J. 2(3), 427-434 (2017); View Description Principal Component Analysis Application on Flavonoids Characterization Che Hafizah Che Noh, Nor Fadhillah Mohamed Azmin, Azura Amid Adv. Sci. Technol. Eng. Syst. J. 2(3), 435-440 (2017); View Description A Reconfigurable Metal-Plasma Yagi-Yuda Antenna for Microwave Applications Giulia Mansutti, Davide Melazzi, Antonio-Daniele Capobianco Adv. Sci. Technol. Eng. Syst. J. 2(3), 441-448 (2017); View Description Verifying the Detection Results of Impersonation Attacks in Service Clouds Sarra Alqahtani, Rose Gamble Adv. Sci. Technol. Eng. Syst. J. 2(3), 449-459 (2017); View Description Image Segmentation Using Fuzzy Inference System on YCbCr Color Model Alvaro Anzueto-Rios, Jose Antonio Moreno-Cadenas, Felipe Gómez-Castañeda, Sergio Garduza-Gonzalez Adv. Sci. Technol. Eng. Syst. J. 2(3), 460-468 (2017); View Description Segmented and Detailed Visualization of Anatomical Structures based on Augmented Reality for Health Education and Knowledge Discovery Isabel Cristina Siqueira da Silva, Gerson Klein, Denise Munchen Brandão Adv. Sci. Technol. Eng. Syst. J. 2(3), 469-478 (2017); View Description Intrusion detection in cloud computing based attack patterns and risk assessment Ben Charhi Youssef, Mannane Nada, Bendriss Elmehdi, Regragui Boubker Adv. Sci. Technol. Eng. Syst. J. 2(3), 479-484 (2017); View Description Optimal Sizing and Control Strategy of renewable hybrid systems PV-Diesel Generator-Battery: application to the case of Djanet city of Algeria Adel Yahiaoui, Khelifa Benmansour, Mohamed Tadjine Adv. Sci. Technol. Eng. Syst. J. 2(3), 485-491 (2017); View Description RFID Antenna Near-field Characterization Using a New 3D Magnetic Field Probe Kassem Jomaa, Fabien Ndagijimana, Hussam Ayad, Majida Fadlallah, Jalal Jomaah Adv. Sci. Technol. Eng. Syst. J. 2(3), 492-497 (2017); View Description Design, Fabrication and Testing of a Dual-Range XY Micro-Motion Stage Driven by Voice Coil Actuators Xavier Herpe, Matthew Dunnigan, Xianwen Kong Adv. Sci. Technol. Eng. Syst. J. 2(3), 498-504 (2017); View Description Self-Organizing Map based Feature Learning in Bio-Signal Processing Marwa Farouk Ibrahim Ibrahim, Adel Ali Al-Jumaily Adv. Sci. Technol. Eng. Syst. J. 2(3), 505-512 (2017); View Description A delay-dependent distributed SMC for stabilization of a networked robotic system exposed to external disturbances Fatma Abdelhedi, Nabil Derbel Adv. Sci. Technol. Eng. Syst. J. 2(3), 513-519 (2017); View Description Modelization of cognition, activity and motivation as indicators for Interactive Learning Environment Asmaa Darouich, Faddoul Khoukhi, Khadija Douzi Adv. Sci. Technol. Eng. Syst. J. 2(3), 520-531 (2017); View Description Homemade array of surface coils implementation for small animal magnetic resonance imaging Fernando Yepes-Calderon, Olivier Beuf Adv. Sci. Technol. Eng. Syst. J. 2(3), 532-539 (2017); View Description An Encryption Key for Secure Authentication: The Dynamic Solution Zubayr Khalid, Pritam Paul, Khabbab Zakaria, Himadri Nath Saha Adv. Sci. Technol. Eng. Syst. J. 2(3), 540-544 (2017); View Description Multi-Domain Virtual Network Embedding with Coordinated Link Mapping Shuopeng Li, Mohand Yazid Saidi, Ken Chen Adv. Sci. Technol. Eng. Syst. J. 2(3), 545-552 (2017); View Description Semantic-less Breach Detection of Polymorphic Malware in Federated Cloud." Advances in Science, Technology and Engineering Systems Journal 2, no. 3 (June 2017): 553–61. http://dx.doi.org/10.25046/aj020371.

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Alqahtani, Sarra, and Rose Gamble. "Volume 2, Issue 3, Special issue on Recent Advances in Engineering Systems (Published Papers) Articles Transmit / Received Beamforming for Frequency Diverse Array with Symmetrical frequency offsets Shaddrack Yaw Nusenu Adv. Sci. Technol. Eng. Syst. J. 2(3), 1-6 (2017); View Description Detailed Analysis of Amplitude and Slope Diffraction Coefficients for knife-edge structure in S-UTD-CH Model Eray Arik, Mehmet Baris Tabakcioglu Adv. Sci. Technol. Eng. Syst. J. 2(3), 7-11 (2017); View Description Applications of Case Based Organizational Memory Supported by the PAbMM Architecture Martín, María de los Ángeles, Diván, Mario José Adv. Sci. Technol. Eng. Syst. J. 2(3), 12-23 (2017); View Description Low Probability of Interception Beampattern Using Frequency Diverse Array Antenna Shaddrack Yaw Nusenu Adv. Sci. Technol. Eng. Syst. J. 2(3), 24-29 (2017); View Description Zero Trust Cloud Networks using Transport Access Control and High Availability Optical Bypass Switching Casimer DeCusatis, Piradon Liengtiraphan, Anthony Sager Adv. Sci. Technol. Eng. Syst. J. 2(3), 30-35 (2017); View Description A Derived Metrics as a Measurement to Support Efficient Requirements Analysis and Release Management Indranil Nath Adv. Sci. Technol. Eng. Syst. J. 2(3), 36-40 (2017); View Description Feedback device of temperature sensation for a myoelectric prosthetic hand Yuki Ueda, Chiharu Ishii Adv. Sci. Technol. Eng. Syst. J. 2(3), 41-40 (2017); View Description Deep venous thrombus characterization: ultrasonography, elastography and scattering operator Thibaud Berthomier, Ali Mansour, Luc Bressollette, Frédéric Le Roy, Dominique Mottier Adv. Sci. Technol. Eng. Syst. J. 2(3), 48-59 (2017); View Description Improving customs’ border control by creating a reference database of cargo inspection X-ray images Selina Kolokytha, Alexander Flisch, Thomas Lüthi, Mathieu Plamondon, Adrian Schwaninger, Wicher Vasser, Diana Hardmeier, Marius Costin, Caroline Vienne, Frank Sukowski, Ulf Hassler, Irène Dorion, Najib Gadi, Serge Maitrejean, Abraham Marciano, Andrea Canonica, Eric Rochat, Ger Koomen, Micha Slegt Adv. Sci. Technol. Eng. Syst. J. 2(3), 60-66 (2017); View Description Aviation Navigation with Use of Polarimetric Technologies Arsen Klochan, Ali Al-Ammouri, Viktor Romanenko, Vladimir Tronko Adv. Sci. Technol. Eng. Syst. J. 2(3), 67-72 (2017); View Description Optimization of Multi-standard Transmitter Architecture Using Single-Double Conversion Technique Used for Rescue Operations Riadh Essaadali, Said Aliouane, Chokri Jebali and Ammar Kouki Adv. Sci. Technol. Eng. Syst. J. 2(3), 73-81 (2017); View Description Singular Integral Equations in Electromagnetic Waves Reflection Modeling A. S. Ilinskiy, T. N. Galishnikova Adv. Sci. Technol. Eng. Syst. J. 2(3), 82-87 (2017); View Description Methodology for Management of Information Security in Industrial Control Systems: A Proof of Concept aligned with Enterprise Objectives. Fabian Bustamante, Walter Fuertes, Paul Diaz, Theofilos Toulqueridis Adv. Sci. Technol. Eng. Syst. J. 2(3), 88-99 (2017); View Description Dependence-Based Segmentation Approach for Detecting Morpheme Boundaries Ahmed Khorsi, Abeer Alsheddi Adv. Sci. Technol. Eng. Syst. J. 2(3), 100-110 (2017); View Description Paper Improving Rule Based Stemmers to Solve Some Special Cases of Arabic Language Soufiane Farrah, Hanane El Manssouri, Ziyati Elhoussaine, Mohamed Ouzzif Adv. Sci. Technol. Eng. Syst. J. 2(3), 111-115 (2017); View Description Medical imbalanced data classification Sara Belarouci, Mohammed Amine Chikh Adv. Sci. Technol. Eng. Syst. J. 2(3), 116-124 (2017); View Description ADOxx Modelling Method Conceptualization Environment Nesat Efendioglu, Robert Woitsch, Wilfrid Utz, Damiano Falcioni Adv. Sci. Technol. Eng. Syst. J. 2(3), 125-136 (2017); View Description GPSR+Predict: An Enhancement for GPSR to Make Smart Routing Decision by Anticipating Movement of Vehicles in VANETs Zineb Squalli Houssaini, Imane Zaimi, Mohammed Oumsis, Saïd El Alaoui Ouatik Adv. Sci. Technol. Eng. Syst. J. 2(3), 137-146 (2017); View Description Optimal Synthesis of Universal Space Vector Digital Algorithm for Matrix Converters Adrian Popovici, Mircea Băbăiţă, Petru Papazian Adv. Sci. Technol. Eng. Syst. J. 2(3), 147-152 (2017); View Description Control design for axial flux permanent magnet synchronous motor which operates above the nominal speed Xuan Minh Tran, Nhu Hien Nguyen, Quoc Tuan Duong Adv. Sci. Technol. Eng. Syst. J. 2(3), 153-159 (2017); View Description A synchronizing second order sliding mode control applied to decentralized time delayed multi−agent robotic systems: Stability Proof Marwa Fathallah, Fatma Abdelhedi, Nabil Derbel Adv. Sci. Technol. Eng. Syst. J. 2(3), 160-170 (2017); View Description Fault Diagnosis and Tolerant Control Using Observer Banks Applied to Continuous Stirred Tank Reactor Martin F. Pico, Eduardo J. Adam Adv. Sci. Technol. Eng. Syst. J. 2(3), 171-181 (2017); View Description Development and Validation of a Heat Pump System Model Using Artificial Neural Network Nabil Nassif, Jordan Gooden Adv. Sci. Technol. Eng. Syst. J. 2(3), 182-185 (2017); View Description Assessment of the usefulness and appeal of stigma-stop by psychology students: a serious game designed to reduce the stigma of mental illness Adolfo J. Cangas, Noelia Navarro, Juan J. Ojeda, Diego Cangas, Jose A. Piedra, José Gallego Adv. Sci. Technol. Eng. Syst. J. 2(3), 186-190 (2017); View Description Kinect-Based Moving Human Tracking System with Obstacle Avoidance Abdel Mehsen Ahmad, Zouhair Bazzal, Hiba Al Youssef Adv. Sci. Technol. Eng. Syst. J. 2(3), 191-197 (2017); View Description A security approach based on honeypots: Protecting Online Social network from malicious profiles Fatna Elmendili, Nisrine Maqran, Younes El Bouzekri El Idrissi, Habiba Chaoui Adv. Sci. Technol. Eng. Syst. J. 2(3), 198-204 (2017); View Description Pulse Generator for Ultrasonic Piezoelectric Transducer Arrays Based on a Programmable System-on-Chip (PSoC) Pedro Acevedo, Martín Fuentes, Joel Durán, Mónica Vázquez, Carlos Díaz Adv. Sci. Technol. Eng. Syst. J. 2(3), 205-209 (2017); View Description Enabling Toy Vehicles Interaction With Visible Light Communication (VLC) M. A. Ilyas, M. B. Othman, S. M. Shah, Mas Fawzi Adv. Sci. Technol. Eng. Syst. J. 2(3), 210-216 (2017); View Description Analysis of Fractional-Order 2xn RLC Networks by Transmission Matrices Mahmut Ün, Manolya Ün Adv. Sci. Technol. Eng. Syst. J. 2(3), 217-220 (2017); View Description Fire extinguishing system in large underground garages Ivan Antonov, Rositsa Velichkova, Svetlin Antonov, Kamen Grozdanov, Milka Uzunova, Ikram El Abbassi Adv. Sci. Technol. Eng. Syst. J. 2(3), 221-226 (2017); View Description Directional Antenna Modulation Technique using A Two-Element Frequency Diverse Array Shaddrack Yaw Nusenu Adv. Sci. Technol. Eng. Syst. J. 2(3), 227-232 (2017); View Description Classifying region of interests from mammograms with breast cancer into BIRADS using Artificial Neural Networks Estefanía D. Avalos-Rivera, Alberto de J. Pastrana-Palma Adv. Sci. Technol. Eng. Syst. J. 2(3), 233-240 (2017); View Description Magnetically Levitated and Guided Systems Florian Puci, Miroslav Husak Adv. Sci. Technol. Eng. Syst. J. 2(3), 241-244 (2017); View Description Energy-Efficient Mobile Sensing in Distributed Multi-Agent Sensor Networks Minh T. Nguyen Adv. Sci. Technol. Eng. Syst. J. 2(3), 245-253 (2017); View Description Validity and efficiency of conformal anomaly detection on big distributed data Ilia Nouretdinov Adv. Sci. Technol. Eng. Syst. J. 2(3), 254-267 (2017); View Description S-Parameters Optimization in both Segmented and Unsegmented Insulated TSV upto 40GHz Frequency Juma Mary Atieno, Xuliang Zhang, HE Song Bai Adv. Sci. Technol. Eng. Syst. J. 2(3), 268-276 (2017); View Description Synthesis of Important Design Criteria for Future Vehicle Electric System Lisa Braun, Eric Sax Adv. Sci. Technol. Eng. Syst. J. 2(3), 277-283 (2017); View Description Gestural Interaction for Virtual Reality Environments through Data Gloves G. Rodriguez, N. Jofre, Y. Alvarado, J. Fernández, R. Guerrero Adv. Sci. Technol. Eng. Syst. J. 2(3), 284-290 (2017); View Description Solving the Capacitated Network Design Problem in Two Steps Meriem Khelifi, Mohand Yazid Saidi, Saadi Boudjit Adv. Sci. Technol. Eng. Syst. J. 2(3), 291-301 (2017); View Description A Computationally Intelligent Approach to the Detection of Wormhole Attacks in Wireless Sensor Networks Mohammad Nurul Afsar Shaon, Ken Ferens Adv. Sci. Technol. Eng. Syst. J. 2(3), 302-320 (2017); View Description Real Time Advanced Clustering System Giuseppe Spampinato, Arcangelo Ranieri Bruna, Salvatore Curti, Viviana D’Alto Adv. Sci. Technol. Eng. Syst. J. 2(3), 321-326 (2017); View Description Indoor Mobile Robot Navigation in Unknown Environment Using Fuzzy Logic Based Behaviors Khalid Al-Mutib, Foudil Abdessemed Adv. Sci. Technol. Eng. Syst. J. 2(3), 327-337 (2017); View Description Validity of Mind Monitoring System as a Mental Health Indicator using Voice Naoki Hagiwara, Yasuhiro Omiya, Shuji Shinohara, Mitsuteru Nakamura, Masakazu Higuchi, Shunji Mitsuyoshi, Hideo Yasunaga, Shinichi Tokuno Adv. Sci. Technol. Eng. Syst. J. 2(3), 338-344 (2017); View Description The Model of Adaptive Learning Objects for virtual environments instanced by the competencies Carlos Guevara, Jose Aguilar, Alexandra González-Eras Adv. Sci. Technol. Eng. Syst. J. 2(3), 345-355 (2017); View Description An Overview of Traceability: Towards a general multi-domain model Kamal Souali, Othmane Rahmaoui, Mohammed Ouzzif Adv. Sci. Technol. Eng. Syst. J. 2(3), 356-361 (2017); View Description L-Band SiGe HBT Active Differential Equalizers with Variable, Positive or Negative Gain Slopes Using Dual-Resonant RLC Circuits Yasushi Itoh, Hiroaki Takagi Adv. Sci. Technol. Eng. Syst. J. 2(3), 362-368 (2017); View Description Moving Towards Reliability-Centred Management of Energy, Power and Transportation Assets Kang Seng Seow, Loc K. Nguyen, Kelvin Tan, Kees-Jan Van Oeveren Adv. Sci. Technol. Eng. Syst. J. 2(3), 369-375 (2017); View Description Secure Path Selection under Random Fading Furqan Jameel, Faisal, M Asif Ali Haider, Amir Aziz Butt Adv. Sci. Technol. Eng. Syst. J. 2(3), 376-383 (2017); View Description Security in SWIPT with Power Splitting Eavesdropper Furqan Jameel, Faisal, M Asif Ali Haider, Amir Aziz Butt Adv. Sci. Technol. Eng. Syst. J. 2(3), 384-388 (2017); View Description Performance Analysis of Phased Array and Frequency Diverse Array Radar Ambiguity Functions Shaddrack Yaw Nusenu Adv. Sci. Technol. Eng. Syst. J. 2(3), 389-394 (2017); View Description Adaptive Discrete-time Fuzzy Sliding Mode Control For a Class of Chaotic Systems Hanene Medhaffar, Moez Feki, Nabil Derbel Adv. Sci. Technol. Eng. Syst. J. 2(3), 395-400 (2017); View Description Fault Tolerant Inverter Topology for the Sustainable Drive of an Electrical Helicopter Igor Bolvashenkov, Jörg Kammermann, Taha Lahlou, Hans-Georg Herzog Adv. Sci. Technol. Eng. Syst. J. 2(3), 401-411 (2017); View Description Computational Intelligence Methods for Identifying Voltage Sag in Smart Grid Turgay Yalcin, Muammer Ozdemir Adv. Sci. Technol. Eng. Syst. J. 2(3), 412-419 (2017); View Description A Highly-Secured Arithmetic Hiding cum Look-Up Table (AHLUT) based S-Box for AES-128 Implementation Ali Akbar Pammu, Kwen-Siong Chong, Bah-Hwee Gwee Adv. Sci. Technol. Eng. Syst. J. 2(3), 420-426 (2017); View Description Service Productivity and Complexity in Medical Rescue Services Markus Harlacher, Andreas Petz, Philipp Przybysz, Olivia Chaillié, Susanne Mütze-Niewöhner Adv. Sci. Technol. Eng. Syst. J. 2(3), 427-434 (2017); View Description Principal Component Analysis Application on Flavonoids Characterization Che Hafizah Che Noh, Nor Fadhillah Mohamed Azmin, Azura Amid Adv. Sci. Technol. Eng. Syst. J. 2(3), 435-440 (2017); View Description A Reconfigurable Metal-Plasma Yagi-Yuda Antenna for Microwave Applications Giulia Mansutti, Davide Melazzi, Antonio-Daniele Capobianco Adv. Sci. Technol. Eng. Syst. J. 2(3), 441-448 (2017); View Description Verifying the Detection Results of Impersonation Attacks in Service Clouds." Advances in Science, Technology and Engineering Systems Journal 2, no. 3 (May 2017): 449–59. http://dx.doi.org/10.25046/aj020358.

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Clemente, Frances. "Alienation, Innocence, and Death in Naples: Unmasking the Poetic World of Antonio De Curtis." Italianist, April 5, 2024, 1–20. http://dx.doi.org/10.1080/02614340.2024.2327238.

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Short, Meghan I., Robert Hudson, Benjamin D. Besasie, Kelly R. Reveles, Dimpy P. Shah, Susannah Nicholson, Teresa L. Johnson-Pais, et al. "Comparison of rectal swab, glove tip, and participant-collected stool techniques for gut microbiome sampling." BMC Microbiology 21, no. 1 (January 14, 2021). http://dx.doi.org/10.1186/s12866-020-02080-3.

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Abstract Background Studies of the gut microbiome are becoming increasingly important. Such studies require stool collections that can be processed or frozen in a timely manner so as not to alter the microbial content. Due to the logistical difficulties of home-based stool collection, there has been a challenge in selecting the appropriate sample collection technique and comparing results from different microbiome studies. Thus, we compared stool collection and two alternative clinic-based fecal microbiome collection techniques, including a newer glove-based collection method. Results We prospectively enrolled 22 adult men from our prostate cancer screening cohort SABOR (San Antonio Biomarkers of Risk for prostate cancer) in San Antonio, TX, from 8/2018 to 4/2019. A rectal swab and glove tip sample were collected from each participant during a one-time visit to our clinics. A single stool sample was collected at the participant’s home. DNA was isolated from the fecal material and 16 s rRNA sequencing of the V1-V2 and V3-V4 regions was performed. We found the gut microbiome to be similar in richness and evenness, noting no differences in alpha diversity among the collection methods. The stool collection method, which remains the gold-standard method for the gut microbiome, proved to have different community composition compared to swab and glove tip techniques (p< 0.001) as measured by Bray-Curtis and unifrac distances. There were no significant differences in between the swab and glove tip samples with regard to beta diversity (p> 0.05). Despite differences between home-based stool and office-based fecal collection methods, we noted that the distance metrics for the three methods cluster by participant indicating within-person similarities. Additionally, no taxa differed among the methods in a Linear Discriminant Analysis Effect Size (LEfSe) analysis comparing all-against-all sampling methods. Conclusion The glove tip method provides similar gut microbiome results as rectal swab and stool microbiome collection techniques. The addition of a new office-based collection technique could help easy and practical implementation of gut microbiome research studies and clinical practice.
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Izzi, Benedetta, Simona Costanzo, Alessandro Gialluisi, Amalia De Curtis, Sara Magnacca, Teresa Panzera, Augusto Di Castelnuovo, et al. "Platelet distribution width is associated with cardiovascular mortality in an adult general population." Bleeding, Thrombosis, and Vascular Biology 2, no. 3 (September 27, 2023). http://dx.doi.org/10.4081/btvb.2023.83.

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Platelet distribution width (PDW), a marker of platelet size heterogeneity used as a readout of processes leading to platelet production and destruction, was recently reported to tag platelet activation variability. As platelets participate in the pathogenesis of many acute and chronic diseases, we evaluated PDW as a predictor of all-cause and cause-specific mortality. Longitudinal analysis was performed on 17,334 participants (52% women, mean age 55.6±12 years) in the Moli-sani study cohort, without a history of hematological diseases. Baseline PDW measurements were categorized in tertiles, the lowest acting as the reference. A multivariable Cox-proportional hazard model was used to estimate the association between PDW and mortality. Over a median follow-up of 11.6 years (interquartile range 10.7-12.5), 1,535 deaths [37.7% cardiovascular disease (CVD) and 36.5% cancer] were ascertained. As compared to those in the first PDW tertile (14.6-16.0 fL), individuals within the highest tertile (16.6-20.4 fL) had an increased risk of all-cause [hazard ratios (HR):1.20; 95% CI: 1.04-1.37] and CVD mortality (HR:1.29; 1.03-1.62). No association between PDW and cancer mortality was found in the whole sample. Subgroup analyses by two age classes (35-65y, ≥65y) showed that the association of PDW with both all-cause and cancer mortality was more apparent in the elderly (HR:1.34; 1.14-1.58, P for interaction =0.028 and HR:1.37; 1.01-1.85, P for interaction =0.020, respectively). We conclude that PDW-associated increase in CVD mortality risk could be related to accelerated/altered activation, production, or destruction of platelets, leading to several clinical conditions and death. In the elderly, PDW involvement in all-cause and cancer mortality should be further investigated. *Moli-sani investigatorsSteering committee: Licia Iacoviello, Giovanni de Gaetano, Maria Benedetta Donati. Scientific secretariat: Marialaura Bonaccio, Americo Bonanni, Chiara Cerletti, Simona Costanzo, Amalia De Curtis, Augusto Di Castelnuovo, Alessandro Gialluisi, Francesco Gianfagna, Mariarosaria Persichillo, Teresa Di Prospero. Safety and ethical committee: Jos Vermylen, Renzo Pegoraro, Antonio Spagnolo. External event adjudicating committee: Deodato Assanelli, Livia Rago. Baseline and follow-up data management: Simona Costanzo, Marco Olivieri, Teresa Panzera. Data analysis: Augusto Di Castelnuovo, Marialaura Bonaccio, Simona Costanzo, Simona Esposito, Alessandro Gialluisi, Francesco Gianfagna, Sabatino Orlandi, Emilia Ruggiero, Alfonsina Tirozzi. Biobank, molecular and genetic laboratory: Amalia De Curtis, Sara Magnacca, Fabrizia Noro, Alfonsina Tirozzi. Recruitment staff: Mariarosaria Persichillo, Francesca Bracone, Teresa Panzera. Communication and press office: Americo Bonanni. Regional institutions: Direzione Generale per la Salute - Regione Molise; Azienda Sanitaria Regionale del Molise; Agenzia Regionale per la Protezione Ambientale del Molise; Molise Dati Spa; Offices of vital statistics of the Molise region. Hospitals: Presidi Ospedalieri ASReM: Ospedale A. Cardarelli, Campobasso; Ospedale F. Veneziale, Isernia; Ospedale San Timoteo, Termoli (CB); Ospedale Ss. Rosario, Venafro (IS); Ospedale Vietri, Larino (CB); Ospedale San Francesco Caracciolo, Agnone (IS); Casa di Cura Villa Maria, Campobasso; Ospedale Gemelli Molise, Campobasso; IRCCS Neuromed, Pozzilli (IS), Italy.
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Alves, Murilo Cavalcante. "A metáfora nos sermões de Antonio Vieira: do argumentativo ao sacro-literário." Revista Letras 97 (July 27, 2018). http://dx.doi.org/10.5380/rel.v97i0.56718.

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Seggundo a Retórica Clássica, as figuras de estilo, tais como a antítese, a hipérbole e a metáfora, dentre outras, na medida em que contribuem para o movere - ao suscitar uma emoção, o docere - ao transmitir um conhecimento, e o delectare - ao proporcionar prazer, são também retóricas, por exprimirem argumentos, condensando-os e tornando-os mais expressivos. Desse modo, o presente artigo incursiona pela utilização da metáfora nos sermões de Antonio Vieira, como criadora de sentido, com o objetivo de identificar sua natureza e função. Desse modo, visualiza a metáfora não apenas como elemento estético, mas também discursivo, se bem que a análise dessa figura se subordine a uma análise prévia dos argumentos. Pressupõe, portanto, a utilização de tal recurso como, inicialmente, argumentativa, de acordo com o que preceitua a Retórica Antiga, mas estende sua percepção para sua possível autonomização, por conta das derivações em que incorre ao integrar campos semânticos diferenciados. Para isso, a pesquisa recorreu aos estudiosos dessa questão, como Araújo (2013), Cantel (1959), Curtius (1979), Gontijo, Massimi (2014), Muraro (2003), Oliveira (2008), Saraiva (1980), dentre outros.
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OLIVEIRA, Rita Lírio de. "O TEMPO É CHEGADO: EUCLIDES NETO E OS PRINCÍPIOS DA CONDIÇÃO HUMANA E DA HEGEMONIA." BALEIA NA REDE (Cessada) 1, no. 11 (January 27, 2015). http://dx.doi.org/10.36311/1808-8473.2014.v1n11.4628.

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Este artigo tem como propósito a análise do livro O Tempo é Chegado, do escritor baiano Euclides Neto, tomando como referencial teórico os princípios da condição humana e da hegemonia, propostos respectivamente pelos filósofos Hannah Arendt (2007) e Antonio Gramsci – no caso deste, textos compilados pelo pensador italiano Luciano Gruppi (2000). Para tanto, a princípio, discorre-se e discute-se sobre tais premissas, como ato preparatório para, num segundo momento, analisar as narrativas que compõem o livro e contam a saga dos tipos humanos que compõem o painel social da região cacaueira do sul da Bahia (Brasil), sobretudo no que tange às lutas de classes, visando reconhecer nessas histórias curtas, traços das teorias arendtianas e gramscianas abordadas.
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Patel, Vaishnavi J., Victoria Delano, Aishwarya Juttu, Huraiya Adhora, Aroob Zaheer, Leticia Vargas, and Blaine Jacobs. "The Implications of Socioeconomic Status by ZIP Code on Maternal-Fetal Morbidity and Mortality in San Antonio, Texas." Cureus, February 21, 2024. http://dx.doi.org/10.7759/cureus.54636.

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37

Patnaik, Ronit, Mustafa T. Khan, Seiji Yamaguchi, and Danielle M. Fritze. "Building a Low-Cost and Low-Fidelity Kidney Transplant Model: A Technical Report on the San Antonio Kidney Transplant Model." Cureus, April 6, 2022. http://dx.doi.org/10.7759/cureus.23883.

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GARCIA, Luis Eduardo Veloso. "A CRÔNICA BRASILEIRA E A INTERNET: O ONTEM E O HOJE." Trama 16, no. 38 (June 8, 2020). http://dx.doi.org/10.48075/rt.v16i38.23890.

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O artigo em questão procurará apresentar um quadro amplo sobre a crônica brasileira contemporânea através de sua recepção dentro da Internet nas três últimas décadas, que compreendem o período de popularização e confirmação dessa tecnologia comunicacional, tanto em seu “ontem” (os primórdios da web e o desenvolvimento de novas percepções entre os anos de 1990 e 2010) quanto o seu “hoje” (o olhar para o tempo presente e as possíveis alterações no decorrer dessas décadas). Inicialmente, será abordado o modo como ocorreu a transposição deste gênero legitimamente fundado no jornal para as plataformas digitais, observando o que chamamos de “ontem” da Internet. Entre os destaques, veremos a concepção da crônica nos jornais e revistas em suas versões onlines, as correntes de e-mails, os populares blogs (e a força das “blônicas”) e as redes sociais. Na sequência, intencionamos apresentar como ocorre a recepção do gênero no tempo presente, apontando as alterações que o “hoje” carrega dos primórdios da crônica dentro da Internet, principalmente na passagem da tecnologia de Web 1.0 para Web 2.0. Nosso trabalho, portanto, analisa o quanto um gênero tão popular em nossa literatura como é a crônica pode ter a capacidade de se adaptar da passagem dos suportes impressos para os suportes digitais, continuando a ser extremamente relevante dentro da sociedade brasileira nos dias atuais. ReferênciasARRIGUCCI Jr., D. 1987. Fragmentos sobre a crônica. In: ________. Enigma e Comentário. São Paulo: Companhia das Letras, 1987, p. 51-66.ARRUDA, Felipe. 20 Anos de Internet no Brasil: aonde chegamos? Portal Tecmundo. Disponível em: http://www.tecmundo.com.br/internet/8949-20-anos-de-internet-nobrasil-aonde-chegamos-.htm. Acesso em: 10 nov. 2019.BOTTER, Nelson. Apresentação. In: ________ (Org.). Blônicas. São Paulo: Jaboticaba, 2005.BOYD, Danah; ELLISON, Nicole. Social network sites: definitions, history, and scholarship. Journal of Computer-Mediated Communication, 13 (1), 11, 2007.BRUNNER, Diogo. Autoficção: quais os limites do eu. Disponível em: http://lounge.obviousmag.org/ao_sul_de_lugar_nenhum/2013/10/autoficcao-quais-os-limites-do-eu.html. Acesso em: 10 nov. 2019.CALDAS, Aulete. Dicionário Contemporâneo da Língua Portuguesa: Dicionário Caldas Aulete, versão online. Disponível em: http://www.aulete.com.br/ acesso em: 10 nov. 2019.CANDIDO, Antonio. A vida ao rés-do-chão. In: Candido, Antonio (et al). A crônica: o gênero, sua fixação e suas transformações no Brasil. Campinas: Ed. Unicamp; Rio de Janeiro: Fundação Casa de Rui Barbosa, 1992. p. 13-22.COSTA, Caio Tulio. Rumos do Jornalismo. Pesquisa Fapesp, nº 220, junho de 2014, p. 82-85.DUVIVIER, Gregorio. Caviar é uma Ova. São Paulo: Companhia das Letras, 2016.HOUAISS, Instituto Antonio. Dicionário Eletrônico Houaiss da Língua Portuguesa: Versão 3.0. São Paulo: Objetiva, 2009.INSTITUTO VERIFICADOR DE COMUNICAÇÃO (IVC). Dados da Pesquisa. Disponível em: https://www.ivcbrasil.org.br/#/home . Acesso em: 10 nov. 2019.PEREIRA, Luis Fernando da Rocha. O adiantado do minuto: a Internet e os novos rumos do Jornalismo. Disponível em: http://www.bocc.ubi.pt/pag/pereira-luis-novos-rumos-do-jornalismo.pdf Acesso em: 10 nov. 2019.PRATA, Antonio. A Internet fez a crônica reviver... Folha de São Paulo, São Paulo, online, 9 set. 2014.RIBEIRO, José Carlos; AYRES, Marcel. Breves comentários sobre a Análise de Conversações em sites. PORTO, Cristiane; SANTOS, Edméa (Orgs.). Facebook e educação: publicar, curtir, compartilhar. Campina Grande: Eduepb, 2014.SANTOS, Joaquim Ferreira dos. Introdução. In: ________ (Org.). As cem melhores Crônicas Brasileiras. Rio de Janeiro: Objetiva, 2007.SCHITTINE, Denise. Blog: Comunicação e escrita íntima na Internet. Rio de Janeiro: Civilização Brasileira, 2004.SCHOLLHAMMER, K.E. Ficção Brasileira Contemporânea. Rio de Janeiro: Civilização Brasileira, 2010.Recebido em 10-01-2020 | Aceito em 04-05-2020
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Zottarelli, Lisa K., Xiaohe Xu, Thankam S. Sunil, and Shamatanni Chowdhury. "Just Plain Hot: Examining Summer Daily High Heat Indices and Community-Level Social Vulnerability on Emergency Medical Services On-Scene Responses in San Antonio, Texas, 2015-2018." Cureus, June 3, 2023. http://dx.doi.org/10.7759/cureus.39914.

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Bergonzini, C., S. Raffaelli, M. Prelati, E. Piantato, D. Bertamini, and F. Veglia. "Studio preliminare su un campione di soggetti con diagnosi di disturbo di personalità borderline ricoverati presso il Day Hospital Psichiatrico della Struttura di Psichiatria S.P.D.C. dell’Azienda Ospedaliera “SS. Antonio e Biagio e Cesare Arrigo” di Ales." Working Paper of Public Health 2, no. 1 (June 15, 2013). http://dx.doi.org/10.4081/wpph.2013.6742.

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Obiettivi: Il progetto di ricerca è finalizzato all’osservazione dell’attività del day hospital psichiatrico e alla valutazione dell’efficacia del trattamento su un gruppo di pazienti con diagnosi di Disturbo Borderline di Personalità. Metodologia: Il campione è costituito da un gruppo di 5 pazienti con diagnosi di DBP in terapia presso il day hospital, che saranno seguiti per 6 mesi sia con terapia farmacologica che con una psicoterapia che segue le linee guida del Trattamento basato sulla Mentalizzazione di Bateman &amp; Fonagy. Vi è inoltre un gruppo di controllo omogeneo per diagnosi che verrà trattato per 6 mesi ambulatorialmente solo con terapia farmacologica. Risultati: I primi risultati al follow up effettuato a 6 mesi dall’inizio del trattamento sembrano mostrare che i pazienti seguiti con trattamento integrato psicoterapico e farmacologico all’interno del Day Hospital ottengono risultati migliori relativamente ai parametri comportamentali di auto ed etero lesività, di percezione del benessere e della qualità della vita, rispetto ai pazienti curati esclusivamente attraverso farmacoterapia. Conclusioni: Dai risultati preliminari, il Day Hospital sembra costituire una risorsa funzionale e flessibile per i pazienti con diagnosi di Disturbo di Personalità Borderline. Emerge che l’intensità terapeutica abbinata alla flessibilità del setting offerte permettono ai pazienti di ottenere miglioramenti già a 6 mesi dall’inizio del trattamento.
41

Butcher, Stephanie, Camila Cociña, Alexandre Apsan Frediani, Michele Acuto, Brenda Pérez‐Castro, Jorge Peña‐Díaz, Joiselen Cazanave‐Macías, Braima Koroma, and Joseph Macarthy. "“Emancipatory Circuits of Knowledge” for Urban Equality: Experiences From Havana, Freetown, and Asia." Urban Planning 7, no. 3 (June 2, 2022). http://dx.doi.org/10.17645/up.v7i3.5319.

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Feminist, Southern, and decolonial thinkers have long argued that epistemological questions about how knowledge is produced and whose knowledge is valued and actioned are crucial in addressing inequalities, and a key challenge for planning. This collaborative article interrogates how knowledge is mobilised in urban planning and practice, discussing three experiences which have actively centred often-excluded voices, as a way of disrupting knowledge hierarchies in planning. We term these “emancipatory circuits of knowledge”—processes whereby diverse, situated, and marginalised forms of knowledge are co-produced and mobilised across urban research and planning, to address inequalities. We discuss experiences from the Technological University José Antonio Echeverría (CUJAE), a university in Havana, Cuba, that privileges a fluid and collaborative understanding of universities as social actors; the Sierra Leone Urban Research Centre, a research institute in the city of Freetown, which curates collective and inclusive spaces for community action planning, to challenge the legacies of colonial-era planning; and the Asian Coalition for Housing Rights, a regional network across Asia, which facilitates processes of exchange and co-learning which are highly strategic and situated in context, to advance community-led development. Shared across these “emancipatory circuits” are three “sites of impact” through which these partners have generated changes: encouraging inclusive policy and planning outcomes; shifting the planning praxis of authorities, bureaucrats, and researchers; and nurturing collective trajectories through building solidarities. Examining these three sites and their challenges, we query how urban knowledge is produced and translated towards epistemic justice, examining the tensions and the possibilities for building pathways to urban equality.<p>Shared across these ‘emancipatory circuits’ are three layered ‘sites of impact’ through which these partners have generated changes: encouraging inclusive policy and planning outcomes; shifting the planning praxis of authorities, bureaucrats and researchers; and nurturing collective trajectories through processes of building solidarities. Examining these three sites and their challenges, we query the ways in which urban knowledge is produced and translated towards epistemic justice –examining the tensions and the possibilities for building pathways to urban equality.</p>
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Antonio, Amy Brooke, and David Tuffley. "Promoting Information Literacy in Higher Education through Digital Curation." M/C Journal 18, no. 4 (August 10, 2015). http://dx.doi.org/10.5204/mcj.987.

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This article argues that digital curation—the art and science of searching, analysing, selecting, and organising content—can be used to promote the development of digital information literacy skills among higher education students. Rather than relying on institutionally approved journal articles that have been pre-ordained as suitable for a given purpose, digital curation tools allow students to evaluate the quality of Web based-based content and then present it in an attractive form, all of which contributes to the cultivation of their digital literacy skills. We draw on a case study in which first- year information and communications technology (ICT) students used the digital curation platform Scoop.it to curate an annotated collection of resources pertaining to a particular topic. The notion of curation has undergone a significant transformation in the wake of an increasingly digital society. To “curate,” traditionally referred to as “taking care,” has morphed into a process of cataloguing, accessing, and representing artefacts. In the digital age, curation is a way of sifting, organising, and making sense of the plethora of information; it has become an important life skill without which one cannot fully participate in digital life. Moreover, the ready availability of information, made possible by the ubiquity of Internet technology, makes digital curation an essential skill for the twenty-first 21st century learner. In answer to this need, we are seeing the emergence of suites of digital tools, dubbed “‘curation”’ tools, that meet the perceived need to locate, select, and synthesise Web content into open, user-organised collections. With information overload, a distinctive feature of the Internet, the ability to sift through the noise and dross to select high- quality, relevant content—selected on the basis of authority, currency, and fitness-for-purpose—is indeed a valuable skill. To examine this issue, we performed a case study in which a group of first- year Information and Communication Technology (ICT) students curated Web- based resources to inform an assessment task. We argue that curation platforms, such as Scoop.it, can be effective at cultivating the digital information literacy skills of higher education students. Digital Curation Traditionally, curation is a practice most commonly associated with the Art world— something reserved for the curators of art exhibitions and museums. However, in today’s world, digital curation tools, such as Scoop.it, make it possible for the amateur curator to collect and arrange content pertaining to a particular topic in a professional way. While definitions of curation in the context of the online environment have been proposed (Scime; Wheeler; Rosenbaum), these have not been aligned to the building of core digital information literacy competencies. The digital curator must give due consideration to the materials they choose to include in a digital collection, which necessitates engaging in a certain amount of metacognitive-cognitive reasoning. For the purpose of this article, the following definition of digital curation is proposed: “Curation can be summarised as an active process whereby content/artefacts are purposely selected to be preserved for future access. In the digital environment, additional elements can be leveraged, such as the inclusion of social media to disseminate collected content, the ability for other users to suggest content or leave comments and the critical evaluation and selection of the aggregated content”. (Antonio, Martin, and Stagg).This definition exemplifies the digital information literacy skills at work in the curation of digital content. It can be further broken down to elucidate the core competencies involved: “Curation can be summarised as an active process whereby content/artefacts are purposely selected.” (Antonio, Martin and Stagg). The user, who curates a particular topic, actively chooses the content they want to appear in their collection. The content must be relevant, up-to-date, and from reputable sources or databases. Achieving this requires a degree of information literacy both in terms of justifying the content that is selected and, conversely, that which is not. The second part of the definition is: “In the digital environment, additional elements can be leveraged, such as the inclusion of social media to disseminate collected content, the ability for other users to suggest content or leave comments.” (Antonio, Martin and Stagg). The digital curator is engaged and immersed in Web 2.0 technologies, ranging from the curation tools themselves to social media platforms such as Facebook and Twitter. The use of these tools thus requires at least basic digital literacy skills, which can potentially be further developed through continued engagement with them. Finally, curation involves the “human-mediated automation of content collection.” (Antonio, Martin and Stagg). The curator must accept or reject the content generated by the search algorithm, which necessitates a level of metacognitive-cognitive analysis to determine the value of a piece of content. While there are countless tools laying claim to the digital curation label, including Pinterest, Storify, and Pearltrees, Scoop.it was selected for this study, as the authors consider that it adheres most closely to the stated definition of curation. Scoop.it requires the user to define the sources from which content will be suggested and to make an informed decision about which pieces of content are appropriate for the collection they are creating. This requires the curator to critically evaluate the relevance, currency, and validity (information literacy) of the suggested materials. Additionally, users can include content from other Scoop.it pages, which is referred to as “re-scooping”. Scoop.it therefore relies on an active editorial role undertaken by the user in the selection, or rejection, of content. That is, the owner of a particular collection makes the final decision regarding what will appear on their Scoop.it page. The content is then displayed visually with the collection growing as new content is added. The successful use of Scoop.it depends on the curator’s ability to interpret and critically assess digital information. This study is thus built on the premise that the metacognitive processes inherent in the discovery of traditional, non-Web based information are transferable to the digital environment and Scoop.it can, as such, be utilised for the cultivation of digital information literacy skills. Digital Information Literacy According to the Laboratory for Innovative Technology in Education at the University of Houston, “digital information literacy” refers to the ability to effectively analyse and evaluate evidence; to analyse and evaluate alternate points of view; to synthesise and make connections between information and arguments; and to reflect critically, interpret, and draw conclusions based on analysis. Research suggests that the digital information literacy skills of higher education students are inadequate (White; Antonio, Tuffley and Martin) and that further training in how to assess the value, credibility, and reliability of information is required. According to the CIBER’s Information Behaviour report, students’ often believe that they are information literate (based on their ability to check the validity of sources) and yet, in reality, their methods may not be sufficiently rigorous to qualify. Students may not be adequately equipped with the information literacy skills required to retrieve and critically evaluate sources outside of those that are institutionally provided, such as textbooks and assigned readings. Moreover, a report by the Committee of Inquiry (Hughes) addresses both the digital divide among students and the responsibility of the higher education sector to ensure that students are equipped with the information literacy skills required to search, authenticate, and critically evaluate material from multiple sources. Throughout history, educators have been teaching traditional literacy skills—reading, writing, finding information in libraries—to students. However, in an increasingly digital society, where a wealth of information is available online, higher education institutions need to teach students how to apply these metacognitive skills—searching, retrieving, authenticating, critically evaluating, and attributing material—to the online environment. Many institutions continue to adhere to the age-old practice of exclusive use of peer-reviewed sources for assessment tasks (Antonio and Tuffley). We argue that this is an unnecessary limitation; when students are denied access to non- peer-reviewed Web -based resources, they are not developing the skills they need to determine the credibility of digital information. While it is not suggested that the solution is to simply allow students to use Wikipedia as their primary reference point, we acknowledge that printed texts and journal articles are not the only source of credible, authoritative information. The current study is thus built on the premise that students need opportunities to help them develop their digital information literacy skills and, in order to do this, they must interact with and utilise Web -based content. The desirability of using curation tools for developing students’ digital information literacy skills thus forms the foundation of this article. Method For the purpose of this study, a group of 258 first-year students enrolled in a Communications for ICT course curated digital content for the research component of an assessment task. These ICT students were selected, firstly, because a level of proficiency with digital technology was assumed and, secondly, because previous course evaluations indicated a desire on the part of the students for technology to be integrated into the course, as a traditional essay was deemed unsuitable for ICT students. The assignment consisted of two parts: a written essay about an emerging technology and an annotated bibliography. The students were required to create a Scoop.it presentation on a particular area of technology and curate content that would assist the essay-writing component of the task. On completion of the assessment task, the students submitted their Scoop.it URL to the course lecturer and were invited to complete an anonymous online survey. The survey consisted of 20 questions—eight addressed demographic factors, three were open- ended (qualitative), and nine multiple choice items specifically assessed the students’ beliefs about whether or not the digital curation task had helped them develop their digital information literacy skills. The analysis below pertains to these nine multiple -choice items. Results and Discussion Of the 258 students who completed the assessment task, 89 participated in the survey. The students were asked: “What were the primary benefits of using the curation tool Scoop.it?” The students were permitted to select multiple responses for this item: 69% of participants said the primary benefit of using Scoop.it was “Engaging with my topic”, while 62% said “Learning how to use a new tool”; and 53% said “Learning how to assess the value of Web- based content” was the primary benefit of the curation task. This suggests that the process of digital curation as described in this project could, potentially, be used to enhance students’ digital information literacy skills. It is noteworthy that the participants in this study were not given any specific instructions on how to assess online information before doing the assignment. They were presented with a one-page summary of what constitutes an annotated bibliography; however, a specific set of guidelines for the types of processes that could be considered indicative of digital information literacy skills was not provided. This might have included the date, for currency; author credentials; cross-checking with other sources etc. It is therefore remarkable that more than 50% of respondents believed that the act of curation had positively impacted their performance on this assessment task and enhanced their ability to critically assess the value of Web -based content. This strongly suggests that the simple act of being exposed to online information, and using it in a purposeful way (in this case to research an emerging technology), can aid the development of critical thinking skills. The students were asked to indicate the extent to which they agreed or disagreed with a series of eight statements, each of which addressed a specific component of digital information literacy. Responses were presented on a Likert scale ranging from strongly agree to strongly disagree. The students’ responses for strongly agree and agree and strongly disagree and disagree were conflated. Statement 1: The use of Scoop.it helped me develop my critical thinking skills. 44% of respondents agreed that the curation tool Scoop.it had helped them develop their critical thinking skills and 30% disagreed. Statement 2: As a result of using Scoop.it, I feel I can make judgments about the value of digital content. 43% of respondents agreed and compared to 22% who disagreed that the curation tool Scoop.it had helped them make judgments about the value of digital content. Statement 3: As a result of using Scoop.it, I feel I can synthesise and organise ideas and information. 58% of respondents agreed that curation via Scoop.it helped them synthesise and organise ideas and information, while and 14% disagreed. Statement 4: As a result of using Scoop.it, I feel I can make judgments about the currency of information. 43% of respondents agreed and 21% disagreed that using Scoop.it had assisted them in their ability to make judgments about the currency of information. Statement 5: As a result of using Scoop.it, I feel I can analyse content in depth. 37% of respondents agreed that the curation task had helped them analyse content in-depth. In contrast, 21% disagreed. Statements 1 to 5 each address a specific component of digital information literacy—the ability to think critically; to make judgments about the value of content; to synthesise and organise ideas and information; to make judgments about the currency of the information; and to analyse content in depth. In response to each of these five components, a greater percentage of students agreed than disagreed that the Scoop.it task helped them develop their digital information literacy skills. By its very nature, Scoop.it generates content based on the key-word parameters entered by the user when creating a given topic. The user is then responsible from for trawling through and evaluating this content in order to make an informed decision about what content they wish to appear on their Scoop.it page. As such, it is perhaps not particularly surprising that the students in this study indicated that the practice of curating content helped them develop their digital information literacy skills. It would, however, be interesting to explore whether or not these students were confident in their abilities prior to undertaking the Scoop.it task, as previous research (CIBER) suggests. Without this information, it is difficult to draw conclusions about the success, or otherwise, of the curation task for cultivating the digital information literacy skills of higher education students. Statement 6: As a result of using Scoop.it, I feel able to cite Web-based information. 48% of respondents agreed that using Scoop.it had assisted them in citing Web-based information, while and 24% disagreed. Statement 7: As a result of using Scoop.it, I feel confident in my ability to use Web -based content in my assignments. 52% of respondents believed that using Scoop.it to curate resources had positively contributed to their confidence in using web-based content for their assignments, compared to 17% who disagreed. The results of statements 6 and 7 indicate that further instruction in using and citing non- peer-reviewed online resources may be required; however, this will not be possible if higher education institutions continue to mandate the exclusive use of journal articles and textbooks, to the exclusion of other non-peer- reviewed Web-based information, such as blogs and wikis. More than half of the students were more confident using digital information following the Scoop.it task, which suggests that the opportunity to engage with the alternate sources of information generated by the Scoop.it platform (such as blogs and wikis and digital newspapers) encouraged the students to think critically about how such sources can be incorporated into academic writing. Statement 8: As a result of using Scoop.it, I feel I can distinguish between good and bad Web-based content. While 38% of students who responded to the survey said that using Scoop.it to curate content had enabled them to distinguish between high- and low- quality information, 25% did not believe that this was the case, and an additional 37% were neither confident nor unconfident about distinguishing between good and bad Web-based content. In keeping with previous research (White), the results of this case study suggest that, while many students believed that the Scoop.it task encouraged them to think critically about the quality of non- peer-reviewed digital resources, they are were not necessarily confident in their ability to distinguish good from poor content. The implication, as Hughes contends, is that there is a need for educators to ensure that higher education students are equipped with these metacognitive-cognitive skills prior to leaving university, as it is imperative that we produce graduates who can function in an increasingly digital society. Conclusion The rising tide of digital information in the twenty-first 21st century necessitates the development of new approaches to making sense of the information found on the World Wide Web. Such is the exponentially expanding volume of this information on the Web—so-called ‘big data’—, that, unless a new breed of tools for sifting and arranging information is made available to those who use the Web for information- gathering, their capacity to deal with the volume will be overwhelmed. The new breed of digital curation tools, such as Scoop.it, are a rational response to this emerging issue. We have made the case that, by using digital curation tools to make sense of data, users are able to discern, at least to some extent, the quality and reliability of information. While this is not a substitute for peer-reviewed, academically rigorous sources, digital curation tools arguably have a supplementary role in an educational context—perhaps as a preliminary method for gathering general information about a topic area before diving deeper with peer-reviewed articles in the second pass. This dual perspective may prove to be a beneficial approach, as it has the virtue of considering both the breadth and depth of a topic. Even without formal instruction on assessing the value of Web content, no less than 53% of participants felt the primary benefit of using the digital curation tool was assessing the value of such content. This result strongly indicates the potential benefits of combining digital curation tools with formal, content-evaluation instruction. This represents a promising avenue for future research.References Antonio, A., N. Martin, and A. Stagg. “Engaging Higher Education Students via Digital Curation.” Future Challenges, Sustainable Futures (2012). 10 Feb. 2013 ‹http://www.ascilite.org.au/conferences/wellington12/2012/pagec16a.html›. Antonio, A., D. Tuffley, and N. Martin. “Creating Active Engagement and Cultivating Information Literacy Skills via Scoop.it.” Electric Dreams (2013). 4 May 2015 ‹http://www.ascilite.org.au/conferences/sydney13/program/proceedings.pdf›. Antonio, A., and D. Tuffley. “Creating Educational Networking Opportunities with Scoop.it.” Journal of Creative Communications 9.2 (2014): 185-97. CIBER. “Information Behaviour of the Researcher of the Future.” JISC (2008). 5 May 2015 ‹http://partners.becta.org.uk/index.php?section=rh&catcode=_re_rp_02&rid=15879›. Hughes, A. “Higher Education in a Web 2.0 World.” JISC (2009). 6 May 2015 ‹http://www.jisc.ac.uk/publications/generalpublications/2009/heweb2.aspx›. Laboratory for Innovative Technology in Education. “New Technologies and 21st Century Skills.” (2013). 5 May 2015 ‹http://newtech.coe.uh.edu/›. Rosenbaum, S. “Why Content Curation Is Here to Stay.” Mashable 3 Mar. 2010. 7 May 2015 ‹http://mashable.com/2010/05/03/content-curation-creation/›. Scime, E. “The Content Strategist as Digital Curator.” Dopedata 8 Dec. 2009. 30 May 2012 ‹http://www.dopedata.com/2009/12/08/the-content-strategits-as-digital-curator/›. Wheeler, S. “The Great Collective.” 2011. ‹http://stevewheeler.blogspot.com.au/2011/07/great-collective.html#!/2011/07/great-collective.html›. White, D. “Digital Visitors and Residents: Progress Report.” JISC (2012). 28 May 2012 ‹http://www.oclc.org/research/activities/vandr.html›.
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Hartley, John. "Lament for a Lost Running Order? Obsolescence and Academic Journals." M/C Journal 12, no. 3 (July 15, 2009). http://dx.doi.org/10.5204/mcj.162.

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The academic journal is obsolete. In a world where there are more titles than ever, this is a comment on their form – especially the print journal – rather than their quantity. Now that you can get everything online, it doesn’t really matter what journal a paper appears in; certainly it doesn’t matter what’s in the same issue. The experience of a journal is rapidly obsolescing, for both editors and readers. I’m obviously not the first person to notice this (see, for instance, "Scholarly Communication"; "Transforming Scholarly Communication"; Houghton; Policy Perspectives; Teute), but I do have a personal stake in the process. For if the journal is obsolete then it follows that the editor is obsolete, and I am the editor of the International Journal of Cultural Studies. I founded the IJCS and have been sole editor ever since. Next year will see the fiftieth issue. So far, I have been responsible for over 280 published articles – over 2.25 million words of other people’s scholarship … and counting. We won’t say anything about the words that did not get published, except that the IJCS rejection rate is currently 87 per cent. Perhaps the first point that needs to be made, then, is that obsolescence does not imply lack of success. By any standard the IJCS is a successful journal, and getting more so. It has recently been assessed as a top-rating A* journal in the Australian Research Council’s journal rankings for ERA (Excellence in Research for Australia), the newly activated research assessment exercise. (In case you’re wondering, M/C Journal is rated B.) The ARC says of the ranking exercise: ‘The lists are a result of consultations with the sector and rigorous review by leading researchers and the ARC.’ The ARC definition of an A* journal is given as: Typically an A* journal would be one of the best in its field or subfield in which to publish and would typically cover the entire field/ subfield. Virtually all papers they publish will be of very high quality. These are journals where most of the work is important (it will really shape the field) and where researchers boast about getting accepted.Acceptance rates would typically be low and the editorial board would be dominated by field leaders, including many from top institutions. (Appendix I, p. 21; and see p. 4.)Talking of boasting, I love to prate about the excellent people we’ve published in the IJCS. We have introduced new talent to the field, and we have published new work by some of its pioneers – including Richard Hoggart and Stuart Hall. We’ve also published – among many others – Sara Ahmed, Mohammad Amouzadeh, Tony Bennett, Goran Bolin, Charlotte Brunsdon, William Boddy, Nico Carpentier, Stephen Coleman, Nick Couldry, Sean Cubitt, Michael Curtin, Daniel Dayan, Ben Dibley, Stephanie Hemelryk Donald, John Frow, Elfriede Fursich, Christine Geraghty, Mark Gibson, Paul Gilroy, Faye Ginsberg, Jonathan Gray, Lawrence Grossberg, Judith Halberstam, Hanno Hardt, Gay Hawkins, Joke Hermes, Su Holmes, Desmond Hui, Fred Inglis, Henry Jenkins, Deborah Jermyn, Ariel Heryanto, Elihu Katz, Senator Rod Kemp (Australian government minister), Youna Kim, Agnes Ku, Richard E. Lee, Jeff Lewis, David Lodge (the novelist), Knut Lundby, Eric Ma, Anna McCarthy, Divya McMillin, Antonio Menendez-Alarcon, Toby Miller, Joe Moran, Chris Norris, John Quiggin, Chris Rojek, Jane Roscoe, Jeffrey Sconce, Lynn Spigel, John Storey, Su Tong, the late Sako Takeshi, Sue Turnbull, Graeme Turner, William Uricchio, José van Dijck, Georgette Wang, Jing Wang, Elizabeth Wilson, Janice Winship, Handel Wright, Wu Jing, Wu Qidi (Chinese Vice-Minister of Education), Emilie Yueh-Yu Yeh, Robert Young and Zhao Bin. As this partial list makes clear, as well as publishing the top ‘hegemons’ we also publish work pointing in new directions, including papers from neighbouring disciplines such as anthropology, area studies, economics, education, feminism, history, literary studies, philosophy, political science, and sociology. We have sought to represent neglected regions, especially Chinese cultural studies, which has grown strongly during the past decade. And for quite a few up-and-coming scholars we’ve been the proud host of their first international publication. The IJCS was first published in 1998, already well into the internet era, but it was print-only at that time. Since then, all content, from volume 1:1 onwards, has been digitised and is available online (although vol 1:2 is unaccountably missing). The publishers, Sage Publications Ltd, London, have steadily added online functionality, so that now libraries can get the journal in various packages, including offering this title among many others in online-only bundles, and individuals can purchase single articles online. Thus, in addition to institutional and individual subscriptions, which remain the core business of the journal, income is derived by the publisher from multi-site licensing, incremental consortial sales income, single- and back-issue sales (print), pay-per-view, and deep back file sales (electronic). So what’s obsolete about it? In that boasting paragraph of mine (above), about what wonderful authors we’ve published, lies one of the seeds of obsolescence. For now that it is available online, ‘users’ (no longer ‘readers’!) can search for what they want and ignore the journal as such altogether. This is presumably how most active researchers experience any journal – they are looking for articles (or less: quotations; data; references) relevant to a given topic, literature review, thesis etc. They encounter a journal online through its ‘content’ rather than its ‘form.’ The latter is irrelevant to them, and may as well not exist. The Cover Some losses are associated with this change. First is the loss of the front cover. Now you, dear reader, scrolling through this article online, might well complain, why all the fuss about covers? Internet-generation journals don’t have covers, so all of the work that goes into them to establish the brand, the identity and even the ‘affect’ of a journal is now, well, obsolete. So let me just remind you of what’s at stake. Editors, designers and publishers all take a good deal of trouble over covers, since they are the point of intersection of editorial, design and marketing priorities. Thus, the IJCS cover contains the only ‘content’ of the journal for which we pay a fee to designers and photographers (usually the publisher pays, but in one case I did). Like any other cover, ours has three main elements: title, colour and image. Thought goes into every detail. Title I won’t say anything about the journal’s title as such, except that it was the result of protracted discussions (I suggested Terra Nullius at one point, but Sage weren’t having any of that). The present concern is with how a title looks on a cover. Our title-typeface is Frutiger. Originally designed by Adrian Frutiger for Charles de Gaulle Airport in Paris, it is suitably international, being used for the corporate identity of the UK National Health Service, Telefónica O2, the Royal Navy, the London School of Economics , the Canadian Broadcasting Corporation, the Conservative Party of Canada, Banco Bradesco of Brazil, the Finnish Defence Forces and on road signs in Switzerland (Wikipedia, "Frutiger"). Frutiger is legible, informal, and reads well in small copy. Sage’s designer and I corresponded on which of the words in our cumbersome name were most important, agreeing that ‘international’ combined with ‘cultural’ is the USP (Unique Selling Point) of the journal, so they should be picked out (in bold small-caps) from the rest of the title, which the designer presented in a variety of Frutiger fonts (regular, italic, and reversed – white on black), presumably to signify the dynamism and diversity of our content. The word ‘studies’ appears on a lozenge-shaped cartouche that is also used as a design element throughout the journal, for bullet points, titles and keywords. Colour We used to change this every two years, but since volume 7 it has stabilised with the distinctive Pantone 247, ‘new fuchsia.’ This colour arose from my own environment at QUT, where it was chosen (by me) for the new Creative Industries Faculty’s academic gowns and hoods, and thence as a detailing colour for the otherwise monochrome Creative Industries Precinct buildings. There’s a lot of it around my office, including on the wall and the furniture. New Fuchsia is – we are frequently told – a somewhat ‘girly’ colour, especially when contrasted with the Business Faculty’s blue or Law’s silver; its similarity to the Girlfriend/Dolly palette does introduce a mild ‘politics of prestige’ element, since it is determinedly pop culture, feminised, and non-canonical. Image Right at the start, the IJCS set out to signal its difference from other journals. At that time, all Sage journals had calligraphic colours – but I was insistent that we needed a photograph (I have ‘form’ in this respect: in 1985 I changed the cover of the Australian Journal of Cultural Studies from a line drawing (albeit by Sydney Nolan) to a photograph; and I co-designed the photo-cover of Cultural Studies in 1987). For IJCS I knew which photo I wanted, and Sage went along with the choice. I explained it in the launch issue’s editorial (Hartley, "Editorial"). That original picture, a goanna on a cattle grid in the outback, by Australian photographer Grant Hobson, lasted ten years. Since volume 11 – in time for our second decade – the goanna has been replaced with a picture by Italian-based photographer Patrick Nicholas, called ‘Reality’ (Hartley, "Cover Narrative"). We have also used two other photos as cover images, once each. They are: Daniel Meadows’s 1974 ‘Karen & Barbara’ (Hartley, "Who"); and a 1962 portrait of Richard Hoggart from the National Portrait Gallery in London (Owen & Hartley 2007). The choice of picture has involved intense – sometimes very tense – negotiations with Sage. Most recently, they were adamant the Daniel Meadows picture, which I wanted to use as the long-term replacement of the goanna, was too ‘English’ and they would not accept it. We exchanged rather sharp words before compromising. There’s no need to rehearse the dispute here; the point is that both sides, publisher and editor, felt that vital interests were at stake in the choice of a cover-image. Was it too obscure; too Australian; too English; too provocative (the current cover features, albeit in the deep background, a TV screen-shot of a topless Italian game-show contestant)? Running Order Beyond the cover, the next obsolete feature of a journal is the running order of articles. Obviously what goes in the journal is contingent upon what has been submitted and what is ready at a given time, so this is a creative role within a very limited context, which is what makes it pleasurable. Out of a limited number of available papers, a choice must be made about which one goes first, what order the other papers should follow, and which ones must be held over to the next issue. The first priority is to choose the lead article: like the ‘first face’ in a fashion show (if you don’t know what I mean by that, see FTV.com. It sets the look, the tone, and the standard for the issue. I always choose articles I like for this slot. It sends a message to the field – look at this! Next comes the running order. We have about six articles per issue. It is important to maintain the IJCS’s international mix, so I check for the country of origin, or failing that (since so many articles come from Anglosphere countries like the USA, UK and Australia), the location of the analysis. Attention also has to be paid to the gender balance among authors, and to the mix of senior and emergent scholars. Sometimes a weak article needs to be ‘hammocked’ between two good ones (these are relative terms – everything published in the IJCS is of a high scholarly standard). And we need to think about disciplinary mix, so as not to let the journal stray too far towards one particular methodological domain. Running order is thus a statement about the field – the disciplinary domain – rather than about an individual paper. It is a proposition about how different voices connect together in some sort of disciplinary syntax. One might even claim that the combination of cover and running order is a last vestige of collegiate collectivism in an era of competitive academic individualism. Now all that matters is the individual paper and author; the ‘currency’ is tenure, promotion and research metrics, not relations among peers. The running order is obsolete. Special Issues An extreme version of running order is the special issue. The IJCS has regularly published these; they are devoted to field-shaping initiatives, as follows: Title Editor(s) Issue Date Radiocracy: Radio, Development and Democracy Amanda Hopkinson, Jo Tacchi 3.2 2000 Television and Cultural Studies Graeme Turner 4.4 2001 Cultural Studies and Education Karl Maton, Handel Wright 5.4 2002 Re-Imagining Communities Sara Ahmed, Anne-Marie Fortier 6.3 2003 The New Economy, Creativity and Consumption John Hartley 7.1 2004 Creative Industries and Innovation in China Michael Keane, John Hartley 9.3 2006 The Uses of Richard Hoggart Sue Owen, John Hartley 10.1 2007 A Cultural History of Celebrity Liz Barry 11.3 2008 Caribbean Media Worlds Anna Pertierra, Heather Horst 12.2 2009 Co-Creative Labour Mark Deuze, John Banks 12.5 2009 It’s obvious that special issues have a place in disciplinary innovation – they can draw attention in a timely manner to new problems, neglected regions, or innovative approaches, and thus they advance the field. They are indispensible. But because of online publication, readers are not held to the ‘project’ of a special issue and can pick and choose whatever they want. And because of the peculiarities of research assessment exercises, editing special issues doesn’t count as research output. The incentive to do them is to that extent reduced, and some universities are quite heavy-handed about letting academics ‘waste’ time on activities that don’t produce ‘metrics.’ The special issue is therefore threatened with obsolescence too. Refereeing In many top-rating journals, the human side of refereeing is becoming obsolete. Increasingly this labour-intensive chore is automated and the labour is technologically outsourced from editors and publishers to authors and referees. You have to log on to some website and follow prompts in order to contribute both papers and the assessment of papers; interactions with editors are minimal. At the IJCS the process is still handled by humans – namely, journal administrator Tina Horton and me. We spend a lot of time checking how papers are faring, from trying to find the right referees through to getting the comments and then the author’s revisions completed in time for a paper to be scheduled into an issue. The volume of email correspondence is considerable. We get to know authors and referees. So we maintain a sense of an interactive and conversational community, albeit by correspondence rather than face to face. Doubtless, sooner or later, there will be a depersonalised Text Management System. But in the meantime we cling to the romantic notion that we are involved in refereeing for the sake of the field, for raising the standard of scholarship, for building a globally dispersed virtual college of cultural studies, and for giving everyone – from unfavoured countries and neglected regions to famous professors in old-money universities – the same chance to get their research published. In fact, these are largely delusional ideals, for as everyone knows, refereeing is part of the political economy of publicly-funded research. It’s about academic credentials, tenure and promotion for the individual, and about measurable research metrics for the academic organisation or funding agency (Hartley, "Death"). The IJCS has no choice but to participate: we do what is required to qualify as a ‘double-blind refereed journal’ because that is the only way to maintain repute, and thence the flow of submissions, not to mention subscriptions, without which there would be no journal. As with journals themselves, which proliferate even as the print form becomes obsolete, so refereeing is burgeoning as a practice. It’s almost an industry, even though the currency is not money but time: part gift-economy; part attention-economy; partly the payment of dues to the suzerain funding agencies. But refereeing is becoming obsolete in the sense of gathering an ‘imagined community’ of people one might expect to know personally around a particular enterprise. The process of dispersal and anonymisation of the field is exacerbated by blind refereeing, which we do because we must. This is suited to a scientific domain of objective knowledge, but everyone knows it’s not quite like that in the ‘new humanities’. The agency and identity of the researcher is often a salient fact in the research. The embedded positionality of the author, their reflexiveness about their own context and room-for-manoeuvre, and the radical contextuality of knowledge itself – these are all more or less axiomatic in cultural studies, but they’re not easily served by ‘double-blind’ refereeing. When refereeing is depersonalised to the extent that is now rife (especially in journals owned by international commercial publishers), it is hard to maintain a sense of contextualised productivity in the knowledge domain, much less a ‘common cause’ to which both author and referee wish to contribute. Even though refereeing can still be seen as altruistic, it is in the service of something much more general (‘scholarship’) and much more particular (‘my career’) than the kind of reviewing that wants to share and improve a particular intellectual enterprise. It is this mid-range altruism – something that might once have been identified as a politics of knowledge – that’s becoming obsolete, along with the printed journals that were the banner and rallying point for the cause. If I were to start a new journal (such as cultural-science.org), I would prefer ‘open refereeing’: uploading papers on an open site, subjecting them to peer-review and criticism, and archiving revised versions once they have received enough votes and comments. In other words I’d like to see refereeing shifted from the ‘supply’ or production side of a journal to the ‘demand’ or readership side. But of course, ‘demand’ for ‘blind’ refereeing doesn’t come from readers; it comes from the funding agencies. The Reading Experience Finally, the experience of reading a journal is obsolete. Two aspects of this seem worthy of note. First, reading is ‘out of time’ – it no longer needs to conform to the rhythms of scholarly publication, which are in any case speeding up. Scholarship is no longer seasonal, as it has been since the Middle Ages (with university terms organised around agricultural and ecclesiastical rhythms). Once you have a paper’s DOI number, you can read it any time, 24/7. It is no longer necessary even to wait for publication. With some journals in our field (e.g. Journalism Studies), assuming your Library subscribes, you can access papers as soon as they’re uploaded on the journal’s website, before the published edition is printed. Soon this will be the norm, just as it is for the top science journals, where timely publication, and thereby the ability to claim first discovery, is the basis of intellectual property rights. The IJCS doesn’t (yet) offer this service, but its frequency is speeding up. It was launched in 1998 with three issues a year. It went quarterly in 2001 and remained a quarterly for eight years. It has recently increased to six issues a year. That too causes changes in the reading experience. The excited ripping open of the package is less of a thrill the more often it arrives. Indeed, how many subscribers will admit that sometimes they don’t even open the envelope? Second, reading is ‘out of place’ – you never have to see the journal in which a paper appears, so you can avoid contact with anything that you haven’t already decided to read. This is more significant than might first appear, because it is affecting journalism in general, not just academic journals. As we move from the broadcast to the broadband era, communicative usage is shifting too, from ‘mass’ communication to customisation. This is a mixed blessing. One of the pleasures of old-style newspapers and the TV news was that you’d come across stories you did not expect to find. Indeed, an important attribute of the industrial form of journalism is its success in getting whole populations to read or watch stories about things they aren’t interested in, or things like wars and crises that they’d rather not know about at all. That historic textual achievement is in jeopardy in the broadband era, because ‘the public’ no longer needs to gather around any particular masthead or bulletin to get their news. With Web 2.0 affordances, you can exercise much more choice over what you attend to. This is great from the point of view of maximising individual choice, but sub-optimal in relation to what I’ve called ‘population-gathering’, especially the gathering of communities of interest around ‘tales of the unexpected’ – novelty or anomalies. Obsolete: Collegiality, Trust and Innovation? The individuation of reading choices may stimulate prejudice, because prejudice (literally, ‘pre-judging’) is built in when you decide only to access news feeds about familiar topics, stories or people in which you’re already interested. That sort of thing may encourage narrow-mindedness. It is certainly an impediment to chance discovery, unplanned juxtaposition, unstructured curiosity and thence, perhaps, to innovation itself. This is a worry for citizenship in general, but it is also an issue for academic ‘knowledge professionals,’ in our ever-narrower disciplinary silos. An in-close specialist focus on one’s own area of expertise need no longer be troubled by the concerns of the person in the next office, never mind the next department. Now, we don’t even have to meet on the page. One of the advantages of whole journals, then, is that each issue encourages ‘macro’ as well as ‘micro’ perspectives, and opens reading up to surprises. This willingness to ‘take things on trust’ describes a ‘we’ community – a community of trust. Trust too is obsolete in these days of performance evaluation. We’re assessed by an anonymous system that’s managed by people we’ll never meet. If the ‘population-gathering’ aspects of print journals are indeed obsolete, this may reduce collegiate trust and fellow-feeling, increase individualist competitiveness, and inhibit innovation. In the face of that prospect, I’m going to keep on thinking about covers, running orders, referees and reading until the role of editor is obsolete too. ReferencesHartley, John. "'Cover Narrative': From Nightmare to Reality." International Journal of Cultural Studies 11.2 (2005): 131-137. ———. "Death of the Book?" Symposium of the National Scholarly Communication Forum & Australian Academy of the Humanities, Sydney Maritime Museum, 2005. 26 Apr. 2009 ‹http://www.humanities.org.au/Resources/Downloads/NSCF/RoundTables1-17/PDF/Hartley.pdf›. ———. "Editorial: With Goanna." International Journal of Cultural Studies 1.1 (1998): 5-10. ———. "'Who Are You Going to Believe – Me or Your Own Eyes?' New Decade; New Directions." International Journal of Cultural Studies 11.1 (2008): 5-14. Houghton, John. "Economics of Scholarly Communication: A Discussion Paper." Center for Strategic Economic Studies, Victoria University, 2000. 26 Apr. 2009 ‹http://www.caul.edu.au/cisc/EconomicsScholarlyCommunication.pdf›. Owen, Sue, and John Hartley, eds. The Uses of Richard Hoggart. International Journal of Cultural Studies (special issue), 10.1 (2007). Policy Perspectives: To Publish and Perish. (Special issue cosponsored by the Association of Research Libraries, Association of American Universities and the Pew Higher Education Roundtable) 7.4 (1998). 26 Apr. 2009 ‹http://www.arl.org/scomm/pew/pewrept.html›. "Scholarly Communication: Crisis and Revolution." University of California Berkeley Library. N.d. 26 Apr. 2009 ‹http://www.lib.berkeley.edu/Collections/crisis.html›. Teute, F. J. "To Publish or Perish: Who Are the Dinosaurs in Scholarly Publishing?" Journal of Scholarly Publishing 32.2 (2001). 26 Apr. 2009 ‹http://www.utpjournals.com/product/jsp/322/perish5.html›."Transforming Scholarly Communication." University of Houston Library. 2005. 26 Apr. 2009 ‹http://info.lib.uh.edu/scomm/transforming.htm›.
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Eades, David. "Resilience and Refugees: From Individualised Trauma to Post Traumatic Growth." M/C Journal 16, no. 5 (August 28, 2013). http://dx.doi.org/10.5204/mcj.700.

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This article explores resilience as it is experienced by refugees in the context of a relational community, visiting the notions of trauma, a thicker description of resilience and the trajectory toward positive growth through community. It calls for going beyond a Western biomedical therapeutic approach of exploration and adopting more of an emic perspective incorporating the worldview of the refugees. The challenge is for service providers working with refugees (who have experienced trauma) to move forward from a ‘harm minimisation’ model of care to recognition of a facilitative, productive community of people who are in a transitional phase between homelands. Contextualising Trauma Prior to the 1980s, the term ‘trauma’ was not widely used in literature on refugees and refugee mental health, hardly existing as a topic of inquiry until the mid-1980’s (Summerfield 422). It first gained prominence in relation to soldiers who had returned from Vietnam and in need of medical attention after being traumatised by war. The term then expanded to include victims of wars and those who had witnessed traumatic events. Seahorn and Seahorn outline that severe trauma “paralyses you with numbness and uses denial, avoidance, isolation as coping mechanisms so you don’t have to deal with your memories”, impacting a person‘s ability to risk being connected to others, detaching and withdrawing; resulting in extreme loneliness, emptiness, sadness, anxiety and depression (6). During the Civil War in the USA the impact of trauma was referred to as Irritable Heart and then World War I and II referred to it as Shell Shock, Neurosis, Combat Fatigue, or Combat Exhaustion (Seahorn & Seahorn 66, 67). During the twenty-five years following the Vietnam War, the medicalisation of trauma intensified and Post Traumatic Stress Disorder (PTSD) became recognised as a medical-psychiatric disorder in 1980 in the American Psychiatric Association international diagnostic tool Diagnostic Statistical Manual (DSM–III). An expanded description and diagnosis of PTSD appears in the DSM-IV, influenced by the writings of Harvard psychologist and scholar, Judith Herman (Scheper-Hughes 38) The Diagnostic and Statistical Manual (DSM-IV) of Mental Disorders (American Psychiatric Association, 2000) outlines that experiencing the threat of death, injury to oneself or another or finding out about an unexpected or violent death, serious harm, or threat of the same kind to a family member or close person are considered traumatic events (Chung 11); including domestic violence, incest and rape (Scheper-Hughes 38). Another significant development in the medicalisation of trauma occurred in 1998 when the Victorian Foundation for Survivors of Torture (VFST) released an influential report titled ‘Rebuilding Shattered Lives’. This then gave clinical practice a clearer direction in helping people who had experienced war, trauma and forced migration by providing a framework for therapeutic work. The emphasis became strongly linked to personal recovery of individuals suffering trauma, using case management as the preferred intervention strategy. A whole industry soon developed around medical intervention treating people suffering from trauma related problems (Eyber). Though there was increased recognition for the medicalised discourse of trauma and post-traumatic stress, there was critique of an over-reliance of psychiatric models of trauma (Bracken, et al. 15, Summerfield 421, 423). There was also expressed concern that an overemphasis on individual recovery overlooked the socio-political aspects that amplify trauma (Bracken et al. 8). The DSM-IV criteria for PTSD model began to be questioned regarding the category of symptoms being culturally defined from a Western perspective. Weiss et al. assert that large numbers of traumatized people also did not meet the DSM-III-R criteria for PTSD (366). To categorize refugees’ experiences into recognizable, generalisable psychological conditions overlooked a more localized culturally specific understanding of trauma. The meanings given to collective experience and the healing strategies vary across different socio-cultural groupings (Eyber). For example, some people interpret suffering as a normal part of life in bringing them closer to God and in helping gain a better understanding of the level of trauma in the lives of others. Scheper-Hughes raise concern that the PTSD model is “based on a conception of human nature and human life as fundamentally vulnerable, frail, and humans as endowed with few and faulty defence mechanisms”, and underestimates the human capacity to not only survive but to thrive during and following adversity (37, 42). As a helping modality, biomedical intervention may have limitations through its lack of focus regarding people’s agency, coping strategies and local cultural understandings of distress (Eyber). The benefits of a Western therapeutic model might be minimal when some may have their own culturally relevant coping strategies that may vary to Western models. Bracken et al. document case studies where the burial rituals in Mozambique, obligations to the dead in Cambodia, shared solidarity in prison and the mending of relationships after rape in Uganda all contributed to the healing process of distress (8). Orosa et al. (1) asserts that belief systems have contributed in helping refugees deal with trauma; Brune et al. (1) points to belief systems being a protective factor against post-traumatic disorders; and Peres et al. highlight that a religious worldview gives hope, purpose and meaning within suffering. Adopting a Thicker Description of Resilience Service providers working with refugees often talk of refugees as ‘vulnerable’ or ‘at risk’ populations and strive for ‘harm minimisation’ among the population within their care. This follows a critical psychological tradition, what (Ungar, Constructionist) refers to as a positivist mode of inquiry that emphasises the predictable relationship between risk and protective factors (risk and coping strategies) being based on a ‘deficient’ outlook rather than a ‘future potential’ viewpoint and lacking reference to notions of resilience or self-empowerment (342). At-risk discourses tend to focus upon antisocial behaviours and appropriate treatment for relieving suffering rather than cultural competencies that may be developing in the midst of challenging circumstances. Mares and Newman document how the lives of many refugee advocates have been changed through the relational contribution asylum seekers have made personally to them in an Australian context (159). Individuals may find meaning in communal obligations, contributing to the lives of others and a heightened solidarity (Wilson 42, 44) in contrast to an individual striving for happiness and self-fulfilment. Early naturalistic accounts of mental health, influenced by the traditions of Western psychology, presented thin descriptions of resilience as a quality innate to individuals that made them invulnerable or strong, despite exposure to substantial risk (Ungar, Thicker 91). The interest then moved towards a non-naturalistic contextually relevant understanding of resilience viewed in the social context of people’s lives. Authors such as Benson, Tricket and Birman (qtd. in Ungar, Thicker) started focusing upon community resilience, community capacity and asset-building communities; looking at areas such as - “spending time with friends, exercising control over aspects of their lives, seeking meaningful involvement in their community, attaching to others and avoiding threats to self-esteem” (91). In so doing far more emphasis was given in developing what Ungar (Thicker) refers to as ‘a thicker description of resilience’ as it relates to the lives of refugees that considers more than an ability to survive and thrive or an internal psychological state of wellbeing (89). Ungar (Thicker) describes a thicker description of resilience as revealing “a seamless set of negotiations between individuals who take initiative, and an environment with crisscrossing resources that impact one on the other in endless and unpredictable combinations” (95). A thicker description of resilience means adopting more of what Eyber proposes as an emic approach, taking on an ‘insider perspective’, incorporating the worldview of the people experiencing the distress; in contrast to an etic perspective using a Western biomedical understanding of distress, examined from a position outside the social or cultural system in which it takes place. Drawing on a more anthropological tradition, intervention is able to be built with local resources and strategies that people can utilize with attention being given to cultural traditions within a socio-cultural understanding. Developing an emic approach is to engage in intercultural dialogue, raise dilemmas, test assumptions, document hopes and beliefs and explore their implications. Under this approach, healing is more about developing intelligibility through one’s own cultural and social matrix (Bracken, qtd. in Westoby and Ingamells 1767). This then moves beyond using a Western therapeutic approach of exploration which may draw on the rhetoric of resilience, but the coping strategies of the vulnerable are often disempowered through adopting a ‘therapy culture’ (Furedi, qtd. in Westoby and Ingamells 1769). Westoby and Ingamells point out that the danger is by using a “therapeutic gaze that interprets emotions through the prism of disease and pathology”, it then “replaces a socio-political interpretation of situations” (1769). This is not to dismiss the importance of restoring individual well-being, but to broaden the approach adopted in contextualising it within a socio-cultural frame. The Relational Aspect of Resilience Previously, the concept of the ‘resilient individual’ has been of interest within the psychological and self-help literature (Garmezy, qtd. in Wilson) giving weight to the aspect of it being an innate trait that individuals possess or harness (258). Yet there is a need to explore the relational aspect of resilience as it is embedded in the network of relationships within social settings. A person’s identity and well-being is better understood in observing their capacity to manage their responses to adverse circumstances in an interpersonal community through the networks of relationships. Brison, highlights the collective strength of individuals in social networks and the importance of social support in the process of recovery from trauma, that the self is vulnerable to be affected by violence but resilient to be reconstructed through the help of others (qtd. in Wilson 125). This calls for what Wilson refers to as a more interdisciplinary perspective drawing on cultural studies and sociology (2). It also acknowledges that although individual traits influence the action of resilience, it can be learned and developed in adverse situations through social interactions. To date, within sociology and cultural studies, there is not a well-developed perspective on the topic of resilience. Resilience involves a complex ongoing interaction between individuals and their social worlds (Wilson 16) that helps them make sense of their world and adjust to the context of resettlement. It includes developing a perspective of people drawing upon negative experiences as productive cultural resources for growth, which involves seeing themselves as agents of their own future rather than suffering from a sense of victimhood (Wilson 46, 258). Wilson further outlines the display of a resilience-related capacity to positively interpret and derive meaning from what might have been otherwise negative migration experiences (Wilson 47). Wu refers to ‘imagineering’ alternative futures, for people to see beyond the current adverse circumstances and to imagine other possibilities. People respond to and navigate their experience of trauma in unique, unexpected and productive ways (Wilson 29). Trauma can cripple individual potential and yet individuals can also learn to turn such an experience into a positive, productive resource for personal growth. Grief, despair and powerlessness can be channelled into hope for improved life opportunities. Social networks can act as protection against adversity and trauma; meaningful interpersonal relationships and a sense of belonging assist individuals in recovering from emotional strain. Wilson asserts that social capabilities assist people in turning what would otherwise be negative experiences into productive cultural resources (13). Graybeal (238) and Saleeby (297) explore resilience as a strength-based practice, where individuals, families and communities are seen in relation to their capacities, talents, competencies, possibilities, visions, values and hopes; rather than through their deficiencies, pathologies or disorders. This does not present an idea of invulnerability to adversity but points to resources for navigating adversity. Resilience is not merely an individual trait or a set of intrinsic behaviours that can be displayed in ‘resilient individuals’. Resilience, rather than being an unchanging attribute, is a complex socio-cultural phenomenon, a relational concept of a dynamic nature that is situated in interpersonal relations (Wilson 258). Positive Growth through a Community Based Approach Through migrating to another country (in the context of refugees), Falicov, points out that people often experience a profound loss of their social network and cultural roots, resulting in a sense of homelessness between two worlds, belonging to neither (qtd. in Walsh 220). In the ideological narratives of refugee movements and diasporas, the exile present may be collectively portrayed as a liminality, outside normal time and place, a passage between past and future (Eastmond 255). The concept of the ‘liminal’ was popularised by Victor Turner, who proposed that different kinds of marginalised people and communities go through phases of separation, ‘liminali’ (state of limbo) and reincorporation (qtd. in Tofighian 101). Difficulties arise when there is no closure of the liminal period (fleeing their former country and yet not being able to integrate in the country of destination). If there is no reincorporation into mainstream society then people become unsettled and feel displaced. This has implications for their sense of identity as they suffer from possible cultural destabilisation, not being able to integrate into the host society. The loss of social supports may be especially severe and long-lasting in the context of displacement. In gaining an understanding of resilience in the context of displacement, it is important to consider social settings and person-environment transactions as displaced people seek to experience a sense of community in alternative ways. Mays proposed that alternative forms of community are central to community survival and resilience. Community is a source of wellbeing for building and strengthening positive relations and networks (Mays 590). Cottrell, uses the concept of ‘community competence’, where a community provides opportunities and conditions that enable groups to navigate their problems and develop capacity and resourcefulness to cope positively with adversity (qtd. in Sonn and Fisher 4, 5). Chaskin, sees community as a resilient entity, countering adversity and promoting the well-being of its members (qtd. in Canavan 6). As a point of departure from the concept of community in the conventional sense, I am interested in what Ahmed and Fortier state as moments or sites of connection between people who would normally not have such connection (254). The participants may come together without any presumptions of ‘being in common’ or ‘being uncommon’ (Ahmed and Fortier 254). This community shows little differentiation between those who are welcome and those who are not in the demarcation of the boundaries of community. The community I refer to presents the idea as ‘common ground’ rather than commonality. Ahmed and Fortier make reference to a ‘moral community’, a “community of care and responsibility, where members readily acknowledge the ‘social obligations’ and willingness to assist the other” (Home office, qtd. in Ahmed and Fortier 253). Ahmed and Fortier note that strong communities produce caring citizens who ensure the future of caring communities (253). Community can also be referred to as the ‘soul’, something that stems out of the struggle that creates a sense of solidarity and cohesion among group members (Keil, qtd. in Sonn and Fisher 17). Often shared experiences of despair can intensify connections between people. These settings modify the impact of oppression through people maintaining positive experiences of belonging and develop a positive sense of identity. This has enabled people to hold onto and reconstruct the sociocultural supplies that have come under threat (Sonn and Fisher 17). People are able to feel valued as human beings, form positive attachments, experience community, a sense of belonging, reconstruct group identities and develop skills to cope with the outside world (Sonn and Fisher, 20). Community networks are significant in contributing to personal transformation. Walsh states that “community networks can be essential resources in trauma recovery when their strengths and potential are mobilised” (208). Walsh also points out that the suffering and struggle to recover after a traumatic experience often results in remarkable transformation and positive growth (208). Studies in post-traumatic growth (Calhoun & Tedeschi) have found positive changes such as: the emergence of new opportunities, the formation of deeper relationships and compassion for others, feelings strengthened to meet future life challenges, reordered priorities, fuller appreciation of life and a deepening spirituality (in Walsh 208). As Walsh explains “The effects of trauma depend greatly on whether those wounded can seek comfort, reassurance and safety with others. Strong connections with trust that others will be there for them when needed, counteract feelings of insecurity, hopelessness, and meaninglessness” (208). Wilson (256) developed a new paradigm in shifting the focus from an individualised approach to trauma recovery, to a community-based approach in his research of young Sudanese refugees. Rutter and Walsh, stress that mental health professionals can best foster trauma recovery by shifting from a predominantly individual pathology focus to other treatment approaches, utilising communities as a capacity for healing and resilience (qtd. in Walsh 208). Walsh highlights that “coming to terms with traumatic loss involves making meaning of the trauma experience, putting it in perspective, and weaving the experience of loss and recovery into the fabric of individual and collective identity and life passage” (210). Landau and Saul, have found that community resilience involves building community and enhancing social connectedness by strengthening the system of social support, coalition building and information and resource sharing, collective storytelling, and re-establishing the rhythms and routines of life (qtd. in Walsh 219). Bracken et al. suggest that one of the fundamental principles in recovery over time is intrinsically linked to reconstruction of social networks (15). This is not expecting resolution in some complete ‘once and for all’ getting over it, getting closure of something, or simply recovering and moving on, but tapping into a collective recovery approach, being a gradual process over time. Conclusion A focus on biomedical intervention using a biomedical understanding of distress may be limiting as a helping modality for refugees. Such an approach can undermine peoples’ agency, coping strategies and local cultural understandings of distress. Drawing on sociology and cultural studies, utilising a more emic approach, brings new insights to understanding resilience and how people respond to trauma in unique, unexpected and productive ways for positive personal growth while navigating the experience. This includes considering social settings and person-environment transactions in gaining an understanding of resilience. Although individual traits influence the action of resilience, it can be learned and developed in adverse situations through social interactions. Social networks and capabilities can act as a protection against adversity and trauma, assisting people to turn what would otherwise be negative experiences into productive cultural resources (Wilson 13) for improved life opportunities. The promotion of social competence is viewed as a preventative intervention to promote resilient outcomes, as social skill facilitates social integration (Nettles and Mason 363). As Wilson (258) asserts that resilience is not merely an individual trait or a set of intrinsic behaviours that ‘resilient individuals’ display; it is a complex, socio-cultural phenomenon that is situated in interpersonal relations within a community setting. References Ahmed, Sara, and Anne-Marie Fortier. “Re-Imagining Communities.” International of Cultural Studies 6.3 (2003): 251-59. Bracken, Patrick. J., Joan E. Giller, and Derek Summerfield. Psychological Response to War and Atrocity: The Limitations of Current Concepts. Elsevier Science, 1995. 8 Aug, 2013 ‹http://www.freedomfromtorture.org/sites/default/files/documents/Summerfield-PsychologicalResponses.pdf>. Brune, Michael, Christian Haasen, Michael Krausz, Oktay Yagdiran, Enrique Bustos and David Eisenman. “Belief Systems as Coping Factors for Traumatized Refugees: A Pilot Study.” Eur Psychiatry 17 (2002): 451-58. Canavan, John. “Resilience: Cautiously Welcoming a Contested Concept.” Child Care in Practice 14.1 (2008): 1-7. Chung, Juna. Refugee and Immigrant Survivors of Trauma: A Curriculum for Social Workers. Master’s Thesis for California State University. Long Beach, 2010. 1-29. Eastmond, Maria. “Stories of Lived Experience: Narratives in Forced Migration Research.” Journal of Refugee Studies 20.2 (2007): 248-64. Eyber, Carola “Cultural and Anthropological Studies.” In Forced Migration Online, 2002. 8 Aug, 2013. ‹http://www.forcedmigration.org/research-resources/expert-guides/psychosocial- issues/cultural-and-anthropological-studies>. Graybeal, Clay. “Strengths-Based Social Work Assessment: Transforming the Dominant Paradigm.” Families in Society 82.3 (2001): 233-42. Kleinman, Arthur. “Triumph or Pyrrhic Victory? The Inclusion of Culture in DSM-IV.” Harvard Rev Psychiatry 4 (1997): 343-44. Mares, Sarah, and Louise Newman, eds. Acting from the Heart- Australian Advocates for Asylum Seekers Tell Their Stories. Sydney: Finch Publishing, 2007. Mays, Vicki M. “Identity Development of Black Americans: The Role of History and the Importance of Ethnicity.” American Journal of Psychotherapy 40.4 (1986): 582-93. Nettles, Saundra Murray, and Michael J. Mason. “Zones of Narrative Safety: Promoting Psychosocial Resilience in Young People.” The Journal of Primary Prevention 25.3 (2004): 359-73. Orosa, Francisco J.E., Michael Brune, Katrin Julia Fischer-Ortman, and Christian Haasen. “Belief Systems as Coping Factors in Traumatized Refugees: A Prospective Study.” Traumatology 17.1 (2011); 1-7. Peres, Julio F.P., Alexander Moreira-Almeida, Antonia, G. Nasello, and Harold, G. Koenig. “Spirituality and Resilience in Trauma Victims.” J Relig Health (2006): 1-8. Saleebey, Dennis. “The Strengths Perspective in Social Work Practice: Extensions and Cautions.” Social Work 41.3 (1996): 296-305. Scheper-Hughes, Nancy. “A Talent for Life: Reflections on Human Vulnerability and Resilience.” Ethnos 73.1 (2008): 25-56. Seahorn, Janet, J. and Anthony E. Seahorn. Tears of a Warrior. Ft Collins, USA: Team Pursuits, 2008. Sonn, Christopher, and Adrian Fisher. “Sense of Community: Community Resilient Responses to Oppression and Change.” Unpublished article. Curtin University of Technology & Victoria University of Technology: undated. Summerfield, Derek. “Childhood, War, Refugeedom and ‘Trauma’: Three Core Questions for Medical Health Professionals.” Transcultural Psychiatry 37.3 (2000): 417-433. Tofighian, Omid. “Prolonged Liminality and Comparative Examples of Rioting Down Under”. Fear and Hope: The Art of Asylum Seekers in Australian Detention Centres Literature and Aesthetics (Special Edition) 21 (2011): 97-103. Ungar, Michael. “A Constructionist Discourse on Resilience: Multiple Contexts, Multiple Realities Among at-Risk Children and Youth.” Youth Society 35.3 (2004): 341-365. Ungar, Michael. “A Thicker Description of Resilience.” The International Journal of Narrative Therapy and Community Work 3 & 4 (2005): 85-96. Walsh, Froma. “Traumatic Loss and Major Disasters: Strengthening Family and Community Resilience.” Family Process 46.2 (2007): 207-227. Weiss, Daniel. S., Charles R. Marmar, William. E. Schlenger, John. A. Fairbank, Kathleen Jordon, Richard L. Hough, and Richard A. Kulka. “The Prevalence of Lifetime and Partial Post- Traumatic Stress Disorder in Vietnam Theater Veterans.” Journal of Traumatic Stress 5.3 (1992):365-76. Westoby, Peter, and Ann Ingamells. “A Critically Informed Perspective of Working with Resettling Refugee Groups in Australia.” British Journal of Social Work 40 (2010): 1759-76. Wilson, Michael. “Accumulating Resilience: An Investigation of the Migration and Resettlement Experiences of Young Sudanese People in the Western Sydney Area.” PHD Thesis. University of Western Sydney ( 2012): 1-297. Wu, K. M. “Hope and World Survival.” Philosophy Forum 12.1-2 (1972): 131-48.

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