Добірка наукової літератури з теми "Antiinfluenza"

Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями

Оберіть тип джерела:

Ознайомтеся зі списками актуальних статей, книг, дисертацій, тез та інших наукових джерел на тему "Antiinfluenza".

Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.

Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.

Статті в журналах з теми "Antiinfluenza"

1

Covés-Datson, Evelyn M., Steven R. King, Maureen Legendre, Auroni Gupta, Susana M. Chan, Emily Gitlin, Vikram V. Kulkarni, et al. "A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo." Proceedings of the National Academy of Sciences 117, no. 4 (January 13, 2020): 2122–32. http://dx.doi.org/10.1073/pnas.1915152117.

Повний текст джерела
Анотація:
There is a strong need for a new broad-spectrum antiinfluenza therapeutic, as vaccination and existing treatments are only moderately effective. We previously engineered a lectin, H84T banana lectin (H84T), to retain broad-spectrum activity against multiple influenza strains, including pandemic and avian, while largely eliminating the potentially harmful mitogenicity of the parent compound. The amino acid mutation at position 84 from histidine to threonine minimizes the mitogenicity of the wild-type lectin while maintaining antiinfluenza activity in vitro. We now report that in a lethal mouse model H84T is indeed nonmitogenic, and both early and delayed therapeutic administration of H84T intraperitoneally are highly protective, as is H84T administered subcutaneously. Mechanistically, attachment, which we anticipated to be inhibited by H84T, was only somewhat decreased by the lectin. Instead, H84T is internalized into the late endosomal/lysosomal compartment and inhibits virus–endosome fusion. These studies reveal that H84T is efficacious against influenza virus in vivo, and that the loss of mitogenicity seen previously in tissue culture is also seen in vivo, underscoring the potential utility of H84T as a broad-spectrum antiinfluenza agent.
Стилі APA, Harvard, Vancouver, ISO та ін.
2

DeGoey, David A., Hui-Ju Chen, William J. Flosi, David J. Grampovnik, Clinton M. Yeung, Larry L. Klein, and Dale J. Kempf. "Enantioselective Synthesis of Antiinfluenza Compound A-315675." Journal of Organic Chemistry 67, no. 16 (August 2002): 5445–53. http://dx.doi.org/10.1021/jo0162890.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
3

Traynor, Kate. "Antiinfluenza medication kits need work, FDA advisers conclude." American Journal of Health-System Pharmacy 65, no. 24 (December 15, 2008): 2314–16. http://dx.doi.org/10.2146/news080098.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
4

Sznaidman, Marcos L., Eric A. Meade, Lilia M. Beauchamp, Stuart Russell, and Margaret Tisdale. "The antiinfluenza activity of pyrrolo[2,3-d]pyrimidines." Bioorganic & Medicinal Chemistry Letters 6, no. 5 (March 1996): 565–68. http://dx.doi.org/10.1016/0960-894x(96)00070-4.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
5

Mokrushina, G. A., S. K. Kotovskaya, G. N. Tyurenkova, V. I. Il'enko, V. G. Platonov, and I. V. Kiseleva. "Synthesis of 2-hydrazinobenzimidazoles and their antiinfluenza activity." Pharmaceutical Chemistry Journal 22, no. 2 (February 1988): 146–50. http://dx.doi.org/10.1007/bf00758445.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
6

Ge, Hu, Yi-Fei Wang, Jun Xu, Qiong Gu, Hai-Bo Liu, Pei-Gen Xiao, Jiaju Zhou, Yanhuai Liu, Zirong Yang, and Hua Su. "ChemInform Abstract: Antiinfluenza Agents from Traditional Chinese Medicine." ChemInform 42, no. 13 (March 3, 2011): no. http://dx.doi.org/10.1002/chin.201113269.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
7

Dyason, Jeffrey C., and Mark von Itzstein. "ChemInform Abstract: Antiinfluenza Virus Drug Design: Sialidase Inhibitors." ChemInform 33, no. 29 (May 20, 2010): no. http://dx.doi.org/10.1002/chin.200229266.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
8

Zhang, Chun Jing, and Hai Tao Yu. "The Signal Pathways of Immune Inflammation Mediated by the Tlr3/Nf-Kappab and Activator Protein-1 in Cells Infected with Influenza A Virus Antagonized by Baicalin." Advanced Materials Research 345 (September 2011): 201–9. http://dx.doi.org/10.4028/www.scientific.net/amr.345.201.

Повний текст джерела
Анотація:
Baicalin has better anti-inflammatory function, antioxidant function and antiviral activity, but the mechanism of the antiinfluenza viral activity of baicalin has not been revealed.Toll-like Receptor 3 and the signal pathways mediated by TLR3 were affected and controlled by the infections with influenza A virus. We report here the significant activity and part mechanism of baicalin against H3N2 influenza A viruses. Baicalin could well protect the damages of cells caused by influenza A virus, it also could effectively inhibit the production of CPE in cells caused by influenza A virus and the inhibition of cells growth. The mechanism of antiinfluenza virus infection of baicalin may be related with the following aspects: to decrease the transcriptional activity of the oxidative stress sensitive transcription factor NF-kappaB and AP-1 by moderately decrease the higher expression level of TLR3 mRNA and the higher expression level of protein; and to further inhibit the mRNA expression of the downstream target genes IL-1β, IL-8, RANTES and IFN-β thereby alleviate the inflammatory injuries and restore the stability and balance of immune function in vivro.
Стилі APA, Harvard, Vancouver, ISO та ін.
9

Yoo, Jae-Kwang, Carole L. Galligan, Carl Virtanen, and Eleanor N. Fish. "Identification of a novel antigen-presenting cell population modulating antiinfluenza type 2 immunity." Journal of Experimental Medicine 207, no. 7 (June 14, 2010): 1435–51. http://dx.doi.org/10.1084/jem.20091373.

Повний текст джерела
Анотація:
Antiinfluenza type 2 (T2) immunity contributes to both immunopathology and immunoprotection, yet the underlying mechanisms modulating T2 immunity remain ill defined. We describe a novel mouse antigen (Ag)-presenting cell (APC), designated late-activator APC (LAPC). After pulmonary influenza A (H1N1) virus infection, LAPCs enter the lungs, capture viral Ag, and subsequently migrate to the draining lymph node (DLN) and spleen, with delayed kinetics relative to dendritic cells (DCs). In the DLN, influenza virus–activated LAPCs present Ag and selectively induce T helper type 2 (Th2) effector cell polarization by cell–cell contact–mediated modulation of GATA-3 expression. In adoptive transfer experiments, influenza virus–activated LAPCs augmented Th2 effector T cell responses in the DLN, increased production of circulating antiinfluenza immunoglobulin, and increased levels of T2 cytokines in bronchoalveolar lavage fluid in recipient influenza virus–infected mice. LAPC-recipient mice exhibited exacerbated pulmonary pathology, with delayed viral clearance and enhanced pulmonary eosinophilia. Collectively, our results identify and highlight the importance of LAPCs as immunomodulators of T2 immunity during influenza A virus infection.
Стилі APA, Harvard, Vancouver, ISO та ін.
10

Tuttle, Joel V., Margaret Tisdale, and Thomas A. Krenitsky. "Purine 2'-deoxy-2'-fluororibosides as antiinfluenza virus agents." Journal of Medicinal Chemistry 36, no. 1 (January 1993): 119–25. http://dx.doi.org/10.1021/jm00053a015.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.

Частини книг з теми "Antiinfluenza"

1

Braciale, Vivian Lam. "Generation of CD4+ and CD8+ Antiinfluenza CTL and Assay of In Vitro Cytotoxicity." In Cytotoxic Cells: Recognition, Effector Function, Generation, and Methods, 490–91. Boston, MA: Birkhäuser Boston, 1993. http://dx.doi.org/10.1007/978-1-4684-6814-4_53.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
2

Mondal, Debasis. "Antiinfluenza A Virus Agents." In xPharm: The Comprehensive Pharmacology Reference, 1–2. Elsevier, 2007. http://dx.doi.org/10.1016/b978-008055232-3.61030-x.

Повний текст джерела
Стилі APA, Harvard, Vancouver, ISO та ін.
Ми пропонуємо знижки на всі преміум-плани для авторів, чиї праці увійшли до тематичних добірок літератури. Зв'яжіться з нами, щоб отримати унікальний промокод!

До бібліографії