Готові списки джерел за темами / Antiinfective agents

Добірка наукової літератури з теми "Antiinfective agents"

Автор: Grafiati

Опубліковано: 10 грудня 2022

Оновлено: 29 січня 2023

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Статті в журналах з теми "Antiinfective agents"

Patrick Garidel, Jorg Andra, Jorg Howe, and Thomas Gutsmann. "Novel Antiinflammatory and Antiinfective Agents." Anti-Infective Agents in Medicinal Chemistry 6, no. 3 (July 1, 2007): 185–200. http://dx.doi.org/10.2174/187152107781023647.

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Piplani, Mona, Avtar Chand Rana, and Prabodh Chander Sharma. "Prodrugs of Antiinfective Agents: A Review." Journal of Pharmacy & Pharmaceutical Sciences 19, no. 1 (February 8, 2016): 82. http://dx.doi.org/10.18433/j3x61s.

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Анотація:

Prodrugs are the pharmacologically inactive derivatives of active drugs typically intended to optimize the exposure of active drug at target site, through manipulation of its physicochemical, biopharmaceutical or pharmacokinetic properties. This approach has a number of advantages over conventional drug administration. Antiinfective agents are associated with number of limitations, responsible for their reduced bioavailability. Various antiinfective prodrugs have been synthesized with reduced side effects and improved pharmacological properties. The present paper illustrates different vistas of prodrug approach of antiinfective agents describing brief classification, synthetic approaches, pharmacological aspects and recent patents. It is a very productive area of research and its prologue in human therapy has given triumphant outcomes in improving the clinical and therapeutic effectiveness of drugs.This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

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Thomas, L. D., and G. G. Miller. "Interactions between Antiinfective Agents and Immunosuppressants." American Journal of Transplantation 9 (December 2009): S263—S266. http://dx.doi.org/10.1111/j.1600-6143.2009.02918.x.

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Khalifa, A. E. "Antiinfective Agents Affecting Cognition: A Review." Journal of Chemotherapy 19, no. 6 (December 2007): 620–31. http://dx.doi.org/10.1179/joc.2007.19.6.620.

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Chakraborty, Prasanta. "Gene Clusters from Plants to Microbes: Their Role in Specialized Metabolism and Drug Development." International Journal of Pharmacognosy & Chinese Medicine 2, no. 5 (2018): 1–2. http://dx.doi.org/10.23880/ipcm-16000149.

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Olubadewo, Joseph O., and Ann Ikponmwamba. "Profile of Prescription Medication in a Pediatric Population." Drug Intelligence & Clinical Pharmacy 22, no. 12 (December 1988): 999–1002. http://dx.doi.org/10.1177/106002808802201215.

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This retrospective study describes the prescription medication profile in an outpatient pediatric population (n = 510) retrieved from a hospital pharmacy computer file. The survey covers a three-month period. The study population included 281 male and 229 female patients divided according to age into three groups: infant (age 0–12 months); children (age 1–12 years); and adolescents (age 13–18 years). Medications prescribed were classified according to their pharmacotherapeutic properties as described in the American Hospital Formulary Service Drug Information 87. The findings pointed out that three pharmacotherapeutic categories (the antiinfective/chemotherapeutic, central nervous system (CNS), and respiratory agents) constituted 78.1 percent of the 1402 prescribed medications. The most frequently prescribed agents in each of these categories were, respectively, amoxicillin, aminophylline, and acetaminophen. These agents represent recent advances in drug usage because they became most frequently used only within the past ten years. The age-dependent medication profile indicated that there was a higher prescription rate of antiinfectives and respiratory disorder agents in the younger age groups; in the adolescent group CNS agents were more often prescribed.

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Mardenborough, Leroy G., Xue Y. Zhu, Pincheng Fan, Melissa R. Jacob, Shabana I. Khan, Larry A. Walker, and Seth Y. Ablordeppey. "Identification of bis-quindolines as new antiinfective agents." Bioorganic & Medicinal Chemistry 13, no. 12 (June 2005): 3955–63. http://dx.doi.org/10.1016/j.bmc.2005.04.008.

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Dentali, S. J., and J. J. Hoffmann. "Potential Antiinfective Agents from Eriodictyon angustifolium and Salvia apiana." International Journal of Pharmacognosy 30, no. 3 (January 1992): 223–31. http://dx.doi.org/10.3109/13880209209054003.

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Solé-Lleonart, Candela, Jean-Jacques Rouby, Stijn Blot, Garyfallia Poulakou, Jean Chastre, Lucy B. Palmer, Matteo Bassetti, et al. "Nebulization of Antiinfective Agents in Invasively Mechanically Ventilated Adults." Anesthesiology 126, no. 5 (May 1, 2017): 890–908. http://dx.doi.org/10.1097/aln.0000000000001570.

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Abstract Background Nebulization of antiinfective agents is a common but unstandardized practice in critically ill patients. Methods A systematic review of 1,435 studies was performed in adults receiving invasive mechanical ventilation. Two different administration strategies (adjunctive and substitute) were considered clinically relevant. Inclusion was restricted to studies using jet, ultrasonic, and vibrating-mesh nebulizers. Studies involving children, colonized-but-not-infected adults, and cystic fibrosis patients were excluded. Results Five of the 11 studies included had a small sample size (fewer than 50 patients), and only 6 were randomized. Diversity of case-mix, dosage, and devices are sources of bias. Only a few patients had severe hypoxemia. Aminoglycosides and colistin were the most common antibiotics, being safe regarding nephrotoxicity and neurotoxicity, but increased respiratory complications in 9% (95% CI, 0.01 to 0.18; I2 = 52%), particularly when administered to hypoxemic patients. For tracheobronchitis, a significant decrease in emergence of resistance was evidenced (risk ratio, 0.18; 95% CI, 0.05 to 0.64; I2 = 0%). Similar findings were observed in pneumonia by susceptible pathogens, without improvement in mortality or ventilation duration. In pneumonia caused by resistant pathogens, higher clinical resolution (odds ratio, 1.96; 95% CI, 1.30 to 2.96; I2 = 0%) was evidenced. These findings were not consistently evidenced in the assessment of efficacy against pneumonia caused by susceptible pathogens. Conclusions Performance of randomized trials evaluating the impact of nebulized antibiotics with more homogeneous populations, standardized drug delivery, predetermined clinical efficacy, and safety outcomes is urgently required. Infections by resistant pathogens might potentially have higher benefit from nebulized antiinfective agents. Nebulization, without concomitant systemic administration of the drug, may reduce nephrotoxicity but may also be associated with higher risk of respiratory complications.

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Mullett, Charles J., John C. Christenson, J. Michael Dean, and R. Scott Evans. "A Clinical Decision Support System for Pediatric Antiinfective Agents." Pediatric Research 45, no. 4, Part 2 of 2 (April 1999): 169A. http://dx.doi.org/10.1203/00006450-199904020-01004.

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Більше джерел

Дисертації з теми "Antiinfective agents"

Dentali, Steven John. "Potential antiinfective agents from Eriodictyon angustifolium Nutt. and Salvia apiana Jeps." Diss., The University of Arizona, 1991. http://hdl.handle.net/10150/185511.

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The dichloromethane extracts of twelve US Southwestern herbal remedies were tested against Staphylococcus aureus (9-29 UA), Bacillus subtilis (2-27 UA), Klebsiella pneumoniae (3-9 UA), and Candida brassicae (IFO 1664) in an agar dilution-streak bioassay at 1000 μg/ml. All twelve plants inhibited the growth of B. subtilis. Anemopsis californica, Berberis fendleri, Cacalia decomposita, and Eriodictyon angustifolium inhibited the growth of at least two organisms. Salvia apiana was the only plant in this study to completely inhibit the growth of all four test organisms. After a literature search led to the elimination of A. californica, B. fendleri, and C. decomposita from further study due to reports of their bioactive compounds, Eriodictyon angustifolium Nutt. and Salvia apiana Jeps. were subjected to a detailed bioassay directed chemical investigation. Compounds were isolated by solvent extraction, fractionation and standard chromatographic techniques. They were identified by infrared, mass, and nuclear magnetic resonance spectral analyses, comparison with published spectra and comparison with authentic samples when available. Benzyl-trans-4-coumarate was isolated from E. angustifolium following high performance reverse phase liquid chromatography and subsequently synthesized through the condensation of p-coumaric acid and benzyl alcohol. Estimated at 2.9% of the dichloromethane extract, benzylcoumarate was active against S. aureus (100 μg/ml), B. subtilis (50 μg/ml), and C. albicans (25 μg/ml). Also isolated from E. angustifolium were five flavanones: 4',5,7-trihydroxy-flavanone (naringenin), 4',5-dihydroxy-7-methoxy-flavanone (sakuranetin), 3'-methoxy-4', 5',7-trihydroxy-flavanone (homoeriodictyol), 4',5-dihydroxy-3',7-dimethoxy-flavanone, and 5,7-dihydroxy-3',4'-dimethoxy-flavanone. The dichloromethane extract of S. apiana gave an acid fraction from which the abietane diterpenes carnosic acid and its 16-hydroxy derivative were isolated as their methyl ester acetates. Unstable as free carboxylic acids, these compounds retained activity after methylation but lost activity upon acetylation. Methylation without prior acetylation lead to the formation of 11-methoxy-methylcarnosate, 12-methoxy-methylcarnosate, 16-hydroxy-methylcarnosate, 16-hydroxy-11-methoxy-methylcarnosate, 16-hydroxy-12-methoxy-methylcarnosate, and 11,12-dimethoxy-16-hydroxy-methylcarnosate. At 500 μg/ml 12-methoxy-methylcarnosate was inactive while 16-hydroxy-12-methoxy-methylcarnosate was active against S. aureus, B. subtilis, and C. albicans at 250 μg/ml. From this result it was inferred that the introduction of a 16-hydroxy group increased the bioactivity of carnosic acid.

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Книги з теми "Antiinfective agents"

Bayer, AG Centenary Symposium (1988 Washington D. C. ). Perspectives in antiinfective therapy. Braunschweig: Friedr. Vieweg & Sohn, 1989.

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Bayer Centenary Symposium (1988 Washington, D.C.). Perspectives in antiinfective therapy: Bayer Centenary Symposium, Washington, D.C., Aug. 31.-Sept. 3, 1988. Edited by Jackson George Gee 1920-, Schlumberger H. D. 1933-, and Zeiler H. J. 1947-. Berlin: Springer-Verlag, 1989.

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Food and Agriculture Organization of the United Nations. Animal Production and Health Division., ed. Resistencia a los antiparasitarios: Estado actual con énfasis en América Latina. Roma: Organización de las Naciones Unidas para la Agricultura y la Alimentación, 2003.

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Antibiotic And Chemotherapy Antiinfective Agents And Their Use In Therapy. W.B. Saunders Company, 2010.

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Perspectives in antiinfective therapy: Bayer Centenary Symposium, Washington, D.C., Aug. 31.-Sept. 3, 1988. Springer-Verlag, 1989.

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Clinical Use Of Antiinfective Agents A Guide To What Is Available And How To Prescribe Drugs Used To Treat Infections. Springer, 2012.

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1944-, Cooper James, ed. Antiinfectives in the elderly. New York: Pharmaceutical Products Press, 1995.

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Yu, Yupei. A quantitative structure activity relationships study of antiinfectives based on the nalidixic acid structure. 1987.

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Частини книг з теми "Antiinfective agents"

Jackson, G. G., H. D. Schlumberger, and H. J. Zeiler. "Optimal Use of Antimicrobial Agents." In Perspectives in Antiinfective Therapy, 288–94. Wiesbaden: Vieweg+Teubner Verlag, 1989. http://dx.doi.org/10.1007/978-3-322-86064-4_37.

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Neu, H. C. "Optimal Use of Antimicrobial Agents." In Perspectives in Antiinfective Therapy, 451–60. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-46666-3_38.

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Seydel, J. K. "Modern Strategies in the Design of Antimicrobial Agents." In Perspectives in Antiinfective Therapy, 268–77. Wiesbaden: Vieweg+Teubner Verlag, 1989. http://dx.doi.org/10.1007/978-3-322-86064-4_34.

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Seydel, J. K. "Modern Strategies in the Design of Antimicrobial Agents." In Perspectives in Antiinfective Therapy, 419–35. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-46666-3_35.

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De Clercq, E. "Molecular Targets of Chemotherapeutic Agents Against the Human Immunodeficiency Virus." In Perspectives in Antiinfective Therapy, 255–67. Wiesbaden: Vieweg+Teubner Verlag, 1989. http://dx.doi.org/10.1007/978-3-322-86064-4_33.

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Clercq, E. "Molecular Targets of Chemotherapeutic Agents Against the Human Immunodeficiency Virus." In Perspectives in Antiinfective Therapy, 396–418. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-46666-3_34.

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Faist, E., A. Markewitz, S. Endres, D. Fuchs, L. Hültner, and S. Lang. "Progress in Antiinfective Perioperative Immunomodulatory Therapy with Simultaneous Administration of Blocking and Enhancing Agents." In Host Defense Dysfunction in Trauma, Shock and Sepsis, 1109–29. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-77405-8_146.

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Sobczyński, Jan, and Beata Chudzik-Rząd. "Organic Nanocarriers for the Delivery of Antiinfective Agents." In Nanostructures for Antimicrobial Therapy, 369–93. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-323-46152-8.00016-0.

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Ait-Sidi-Brahim, Malika, Mohammed Markouk, and Mustapha Larhsini. "Moroccan Medicinal Plants as Antiinfective and Antioxidant Agents." In New Look to Phytomedicine, 91–142. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-814619-4.00005-7.

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