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Готові списки джерел за темами / Antibacterial gla

Добірка наукової літератури з теми "Antibacterial gla"

Автор: Grafiati

Опубліковано: 14 березня 2023

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Статті в журналах з теми "Antibacterial gla"

1

Gallagher, Louise, Alanna Smith, Kevin Kavanagh, Michael Devereux, John Colleran, Carmel Breslin, Karl G. Richards, Malachy McCann, and A. Denise Rooney. "Preparation and Antimicrobial Properties of Alginate and Serum Albumin/Glutaraldehyde Hydrogels Impregnated with Silver(I) Ions." Chemistry 3, no. 2 (June 14, 2021): 672–86. http://dx.doi.org/10.3390/chemistry3020047.

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Calcium alginate (CaALG) hydrogel beads and two sets of composite beads, formed from a combination of calcium alginate/propylene glycol alginate/human serum albumin (CaALG/PGA/HSA) and from calcium alginate with the quaternary ammonium salt, (3-(trimethoxysilyl)propyl)-octadecyldimethylammonium chloride (QA), (CaALG/QA), were prepared. Bovine serum albumin (BSA) was condensed with glutaraldehyde (GLA) to form a BSA/GLA hydrogel. The corresponding Ag+-containing gels of all of the above hydrogels were also formed, and slow leaching of the biocidal transition metal ion from the gels bestowed broad spectrum antimicrobial activity. In the absence of added Ag+, CaALG/QA was the only material to deliver marginal to moderate antibacterial and antifungal effects. The Ag+ impregnated hydrogel systems have the potential to maintain the antimicrobial properties of silver, minimising the risk of toxicity, and act as reservoirs to afford ongoing sterility.

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2

Baldwin, Susan L., Sasha E. Larsen, Valerie A. Reese, Tiffany Pecor, Brian Granger, Amit Khandhar, Christopher B. Fox, Steven G. Reed, and Rhea N. Coler. "Use of GLA-nanoalum as an effective adjuvant for a therapeutic ID93 TB vaccine." Journal of Immunology 200, no. 1_Supplement (May 1, 2018): 180.21. http://dx.doi.org/10.4049/jimmunol.200.supp.180.21.

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Abstract Tuberculosis (TB) caused by the intracellular bacterium Mycobacterium tuberculosis (Mtb) reportedly killed 1.3 million people in 2016 and is the leading cause of death caused by a single infectious organism. Increasingly worrisome is the ability of Mtb to develop extensive drug resistance. According to the 2017 WHO global TB report, there were 600,000 new rifampicin-resistant cases in 2016, and almost half a million cases with multiple drug resistant (MDR) TB. The development of new host-targeted therapeutic strategies that prevent the outgrowth of resistant mutants and/or modulate the immune response to combat Mtb infection and/or reduce disease pathology is one solution to prevent the generation of antibacterial resistance and treat drug resistant (DR)-TB. Here we evaluate a novel nanoalum adjuvant formulation containing a synthetic TLR4 agonist, glucopyranosyl lipid adjuvant (GLA), with our clinical ID93 protein as an immunotherapeutic vaccine. We show that immunotherapy with ID93+GLA-nanoalum is effective against Mtb when given as an adjunct to drug treatment in a mouse TB therapy model.

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3

Contini, Cristina, Simone Serrao, Barbara Manconi, Alessandra Olianas, Federica Iavarone, Giulia Guadalupi, Irene Messana, et al. "Characterization of Cystatin B Interactome in Saliva from Healthy Elderly and Alzheimer’s Disease Patients." Life 13, no. 3 (March 10, 2023): 748. http://dx.doi.org/10.3390/life13030748.

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Cystatin B is a small, multifunctional protein involved in the regulation of inflammation, innate immune response, and neuronal protection and found highly abundant in the brains of patients with Alzheimer’s disease (AD). Recently, our study demonstrated a significant association between the level of salivary cystatin B and AD. Since the protein is able to establish protein-protein interaction (PPI) in different contexts and aggregation-prone proteins and the PPI networks are relevant for AD pathogenesis, and due to the relevance of finding new AD markers in peripheral biofluids, we thought it was interesting to study the possible involvement of cystatin B in PPIs in saliva and to evaluate differences and similarities between AD and age-matched elderly healthy controls (HC). For this purpose, we applied a co-immunoprecipitation procedure and a bottom-up proteomics analysis to purify, identify, and quantify cystatin B interactors. Results demonstrated for the first time the existence of a salivary cystatin B-linked multi-protein complex composed by 82 interactors and largely expressed in the body. Interactors are involved in neutrophil activation, antimicrobial activity, modulation of the cytoskeleton and extra-cellular matrix (ECM), and glucose metabolism. Preliminary quantitative data showed significantly lower levels of triosophosphate isomerase 1 and higher levels of mucin 7, BPI, and matrix Gla protein in AD with respect to HC, suggesting implications associated with AD of altered glucose metabolism, antibacterial activities, and calcification-associated processes. Data are available via ProteomeXchange with identifiers PXD039286 and PXD030679.

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4

Łazarski, Grzegorz. "Asperugo Procumbens: a Review of Botany, Traditional Uses, Phytochemistry and Pharmacology." Pakistan Journal of Medical and Health Sciences 15, no. 10 (October 30, 2021): 3092–95. http://dx.doi.org/10.53350/pjmhs2115103092.

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Asperugo procumbens is a medicinal plant widely distributed in the world, which is commonly used in the traditional medicine of the Middle East, while currently overlooked in European pharmacopoeias. The aim of the study is to present a comprehensive overview of A. procumbens in botany, traditional medicine, phytochemistry and pharmacology according to the up-to-date data. Scientific literature on the species was collected based on publicly available databases such as: PubMed, Web of Science, Scopus, Google, Google Scholar as well as monographs and PhD theses. In traditional medicine the aerial part of A. procumbens is used for treatment of skin infections, herpes, liver and respiratory tract diseases, to strengthen the heart and the nervous system, and others. Contemporary studies on the pharmacological activity of A. procumbens revealed that it exhibits a wide range of pharmacological properties, including antioxidant, antidepressant, sedative-hypnotic, antibacterial, as well as chemopreventive and antihypertensive properties. Despite many proven medicinal properties, the species does not have a developed phytochemical profile and its chemical composition is very poorly understood. The species is known to contain tannins, flavonoids and phenolics. Only the content of fatty acids is recognised in detail. The species is a good source of omega-3 fatty acids – stearidonic acid (SDA), α-linolenic acid (ALA), and omega-6 fatty acid – γ-linolenic acid (GLA). This article, based on the available literature, highlights the traditional uses, phytochemistry and pharmacological properties of A. procumbens, which may provide a foundation for further pharmacological study as well as clinical application of the species. Keywords: Asperugo procumbens, German madwort, Boraginaceae, traditional uses

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5

Falk, Shaun P., Andrew T. Ulijasz, and Bernard Weisblum. "Differential Assay for High-Throughput Screening of Antibacterial Compounds." Journal of Biomolecular Screening 12, no. 8 (December 2007): 1102–8. http://dx.doi.org/10.1177/1087057107308161.

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The previously described Bacillus subtilis reporter strain BAU-102 is capable of detecting cell wall synthesis inhibitors that act at all stages of the cell wall synthesis pathway. In addition, this strain is capable of detecting compounds with hydrophobic/ surfactant activity and alternative mechanisms of cell wall disruption. BAU-102 sequesters preformed β-gal in the periplasm, suggesting leakage of β-gal as the means by which this assay detects compound activities. A model is proposed according to which β-gal release by BAU-102 reflects activation of pathways leading to autolysis. The authors also report a simplified high-throughput assay using BAU-102 combined with the fluorogenic substrate N-methylumbelliferyl-β-D-galactoside as a single reagent. Cell wall inhibitors release β-gal consistently only after 60 min of incubation, whereas compounds with surfactant activity show an almost immediate release. A high-throughput screen of a 480-compound library of known bioactives yielded 8 compounds that cause β-gal release. These results validate the BAU-102 assay as an effective tool in antimicrobial drug discovery. ( Journal of Biomolecular Screening 2007:1102-1108)

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6

Zhao, Jing-Li, Meiping Zhang, and Hong-Li Zhou. "Microwave-Assisted Extraction, Purification, Partial Characterization, and Bioactivity of Polysaccharides from Panax ginseng." Molecules 24, no. 8 (April 23, 2019): 1605. http://dx.doi.org/10.3390/molecules24081605.

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Polysaccharides are a main active substance in Panax ginseng; however, microwave-assisted extraction used to prepare P. ginseng polysaccharides (MPPG) has rarely been reported, and knowledge of the bactericidal activity of P. ginseng polysaccharides remains low. Thus, this study was designed to investigate the extraction of P. ginseng polysaccharides by using two methods—hot water extraction and microwave-assisted extraction—and compare their chemical composition and structure. In addition, their antibacterial and antioxidant activities were also determined. The data implied that P. ginseng polysaccharides extracted by microwave-assisted extraction possessed a higher extraction yield than hot water extraction (WPPG) under optimized conditions, and the actual yields were 41.6% ± 0.09% and 28.5% ± 1.62%, respectively. Moreover, the preliminary characterization of polysaccharides was identified after purification. The WPPG with the molecular weight (Mw) of 2.07 × 105 Da was composed of Man, Rib, Rha, GalA, Glu, Gal, and Arab, and the typical characteristics of polysaccharides were determined by IR spectra. Compared with WPPG, MPPG had a higher Mw, uronic acid content, and Glu content. More importantly, the antioxidant activity of MPPG was higher than WPPG, which was probably ascribed to its highly Mw and abundant uronic acid content. Besides, both of them exhibited high bactericidal activity. These results demonstrate that microwave-assisted extraction is an effective method for obtaining P. ginseng polysaccharides, and MPPG could be applied as an antioxidant and antibacterial agent.

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He, Feng, Guang Yang, and Longjiang Yu. "Structural Investigation of an Antibacterial Polysaccharide from Streptomyces virginia H03." Zeitschrift für Naturforschung C 65, no. 5-6 (June 1, 2010): 317–21. http://dx.doi.org/10.1515/znc-2010-5-602.

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The chemical structure of a polysaccharide from the broth of cultured Streptomyces virginia H03 was investigated. There might be 1→2 and 1→4 and no 1→6 glycosidic linkages in the polysaccharide according to periodate oxidation and Smith degradation. Four fragments including 2,3,4,6-Me4-Man, 2,3,6-Me3-Gal, 2,4,6-Me3-Glc, and 3,6-Me2-Man were found in the methylated polysaccharide. Furthermore, the polysaccharide has a β-Glc(1→4)- α-Man(1→4)-α-Gal(1→3)-linked backbone and a branch at the C-2 position of (1→2)-linked mannose residues as determined by the method of nuclear magnetic resonance (NMR) spectroscopy. The assumed structure of the polysaccharide is [→3)-β-Glc(1→4)-α-Man (1→4)-α-Gal(1→]n. 2 ↑ α-Man(1 Additionally, the polysaccharide has a wide antibiogram and was found to be most effective against Bacillus subtilis, Staphylococcus aureus, Listeria monocytogenes, and Escherichia coli.

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Pham, Quoc Thiet, Hieu Trung Nguyen, Sương Thi Thu Phan, Tram Thi Quynh Doan, and Ky Minh Nguyen. "STUDY OF BIOLOGICAL ACTIVITIES OF SLENDER AMARANTH (Amaranthus lividus L.) IN GIA LAI PROVINCE." Scientific Journal of Tra Vinh University 1, no. 36 (April 8, 2020): 64–70. http://dx.doi.org/10.35382/18594816.1.36.2019.317.

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Slender amaranth (Amaranthus lividus L.) is a popular plant in Gia Lai Province, with anti-cancer, antioxidant and antibacterial properties. The study presents the experimental results of biological activity of Amaranthus lividus L. collected in Gia Lai Province. Evaluation of anti-tumor activity (IC50) showed good results with EtOAc and n–hexane with extracts of 8.0 µg/ml and 11.2 µg/ml (≤ 20 µg/ml, NCI) respectively. The comparison results showed that the EtOAc extract from Amaranthus lividus L. has better antibacterial activity than the MeOH extract. However, the investigated extracts from Amaranthus lividus L. were incapable of inhibiting oxidation at low concentrations of 1-64 µg/ml. Results of biologically active ingredients in Amaranthus lividus L. illustratedthe applied prospects of natural medicine sources.

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Falk, Shaun P., James W. Noah, and Bernard Weisblum. "Screen for Inducers of Autolysis in Bacillus subtilis." Antimicrobial Agents and Chemotherapy 54, no. 9 (July 6, 2010): 3723–29. http://dx.doi.org/10.1128/aac.01597-09.

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ABSTRACT We describe a primary high-throughput screen that uses the reporter strain Bacillus subtilis BAU-102 to identify antibiotics that induce autolysis. The screen measures autolysis in terms of the incipient release of recombinant Escherichia coli β-galactosidase (β-Gal) from the periplasmic space of B. subtilis owing to a loss of integrity of the cell wall. In a model screen, β-Gal release values for 79 members of a library consisting of antibiotics and related compounds were collected, sorted, and plotted as a function of rank. Inducers of autolysis, which included compounds that inhibit cell wall synthesis and those that do not, were readily differentiated from other members of the library on the basis of their elevated β-galactosidase release responses. The results of the BAU-102 model screen called attention to the antibacterial activity of drugs normally used in other applications, describable as “repurposed.” Thus, the screen independently identified the potential antibacterial properties of the antifungal drug miconazole and of the antileishmaniasis drug miltefosine. Daptomycin-induced release of β-Gal was also detected and occurred in a Ca2+-dependent manner.

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10

Ito, Yoshiyuki, Yasushi Kawai, Kensuke Arakawa, Yoshiko Honme, Takashi Sasaki, and Tadao Saito. "Conjugative Plasmid from Lactobacillus gasseri LA39 That Carries Genes for Production of and Immunity to the Circular Bacteriocin Gassericin A." Applied and Environmental Microbiology 75, no. 19 (August 7, 2009): 6340–51. http://dx.doi.org/10.1128/aem.00195-09.

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ABSTRACT Gassericin A is a circular bacteriocin produced by Lactobacillus gasseri strain LA39. We found a 33,333-bp plasmid, designated pLgLA39, in this strain. pLgLA39 contained 44 open reading frames, including seven genes related to gassericin A production/immunity (gaa), as well as genes for replication, plasmid maintenance, and conjugative transfer. pLgLA39 was transferred from LA39 to the type strain of L. gasseri (JCM 1131) by filter mating. The transconjugant exhibited >30-fold-higher more resistance to gassericin A and produced antibacterial activity. Lactobacillus reuteri LA6, the producer of reutericin 6, was proved to harbor a plasmid indistinguishable from pLgLA39 and carrying seven genes 100% identical to gaa. This suggests that pLgLA39 might have been transferred naturally between L. gasseri LA39 and L. reuteri LA6. The seven gaa genes of pLgLA39 were cloned into a plasmid vector to construct pGAA. JCM 1131T transformed with pGAA expressed antibacterial activity and resistance to gassericin A. pGAA was segregationally more stable than a pGAA derivative plasmid from which gaaA was deleted and even was more stable than the vector. This suggests the occurrence of postsegregational host killing by the gaa genes. pLgLA39 carried a pemIK homolog, and segregational stabilization of a plasmid by the pLgLA39-type pemIK genes was also confirmed. Thus, pLgLA39 was proved to carry the genes for at least two plasmid maintenance mechanisms, i.e., gaa and pemIK. Plasmids containing a repA gene similar to pLgLA39 repA were distributed in several L. gasseri strains.

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Більше джерел

Дисертації з теми "Antibacterial gla"

1

GALLICHI, NOTTIANI DUCCIO. "Advanced phosphate glasses for photonics: from materials to applications." Doctoral thesis, Politecnico di Torino, 2021. http://hdl.handle.net/11583/2903486.

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Частини книг з теми "Antibacterial gla"

1

Mia Mukul, Mohammad. "Nutraceutical Diversity of Eco-Friendly Jute and Allied Fibre (JAF) Crops in Bangladesh." In Population Genetics [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102664.

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The animal meats contain harmful fat and cholesterol contents but plants are the important sources of secondary metabolites that play important role against diseases, and showed less side effects. Jute, Kenaf and Mesta are self-pollinated annual herbaceous plants used to produce fibre contents. These plants are also used for nutritional purposes. Jute leaves contain vitamins, minerals, energies, macromolecules, phytochemicals, micronutrients, amino acids, anti-oxidants essential to promote human health. Only two species of jute (C. capsularis and C. olitorius) are commercially cultivated for fibre content. Olitorius leaves are sweet but capsularis leaves are bitter in taste. The young twigs and leaves of olitroius jute are used as delicious vegetable, and some capsularis cultivars released in Bangladesh can be used as leafy vegetables at young stage. C. olitorius is known as Molokhia and used as green leafy vegetable (GLV) in African and Eastern countries as a viscous soup. Hibiscus (Kenaf and Mesta) plants have antioxidants, anticancer, antibacterial and anti-cholesterol qualities. These plants produce multi-coloured lovely flowers used to grace our environment. Kenaf (H. Cannabinus) seeds contain essential amino acids and used as feed meals for the birds in different countries. Mesta or Roselle (H. sabdariffa) leaves and calyces have both vegetable and medicinal values.

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Тези доповідей конференцій з теми "Antibacterial gla"

1

Gulsoy Toplan, G., N. Tan, M. Bilgin, M. Gulec, and E. Tan. "Antibacterial activities of Teucrium kotschyanum from Turkey." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608485.

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2

Butt, H. S., E. S. Ulriksen, M. Inngjerdingen, H. Wangensteen, and K. T. Inngjerdingen. "Antibacterial properties of selected Nordic medicinal plants." In GA – 69th Annual Meeting 2021, Virtual conference. Georg Thieme Verlag, 2021. http://dx.doi.org/10.1055/s-0041-1736836.

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3

Vorobets, N., H. Yavorska, and L. Svydenko. "Antibacterial activity of Calamintha mentifolia Host. essential oils." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759234.

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4

Gulsoy Toplan, G., M. Tuysuz, A. Mat, and G. Sariyar. "Antibacterial Activity of Anthemis tricolor Boiss. from Cyprus." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608478.

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5

Brunner, J., A. Smelcerovic, and J. Heilmann. "Prenylated bicyclic acylphloroglucinols from Hypericum tetrapterum with antibacterial activity." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759120.

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6

Laphookhieo, S., I. Polbuppha, V. Suthiphasilp, T. Maneerat, R. C. Charoensup, T. Limtharakul, S. Cheenpracha, and S. Pyne. "Flavonoids and xanthones from Maclura cochinchinensis (Lour.) Corner. and their antibacterial activity." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759090.

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7

Laphookhieo, S., A. Raksat, W. Maneerat, RJ Andersen, and SG Pyne. "Millexatins A-M, antibacterial flavonoids from Millettia extensa." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399906.

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8

Houdkova, M., I. Faltova, J. Zimova, and L. Kokoska. "Antibacterial potential of essential oils from South-East Asian aromatic plants against respiratory pathogens." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759335.

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9

Moujir, L., N. Padilla-Montaño, and L. de León Guerra. "Celastrol: a natural compound with antibacterial properties. Mode of action against Staphylococcus epidermidis." In GA – 69th Annual Meeting 2021, Virtual conference. Georg Thieme Verlag, 2021. http://dx.doi.org/10.1055/s-0041-1736804.

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10

Sungkharak, S., D. Maneenuan, B. Ditsopa, and S. Ungphaiboon. "Enhancement of antibacterial activity against microorganisms involved in diabetes foot ulcer by virgin coconut oil." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608373.

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