Дисертації з теми "Addiction research"
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Wang, Lujiaozi, and Siyu Zhu. "Online Game Addiction Among University Students." Thesis, Högskolan i Gävle, Avdelningen för socialt arbete och psykologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-13757.
Повний текст джерелаBuabeng, Frank K. "Alcohol addiction, bulimia and spirituality : a portfolio of evaluation research and practice." Thesis, City University London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492252.
Повний текст джерелаHenderson, Haley, Valerie Hoots, Joseph Barnet, and Andrea D. Clements. "Employer Perceptions of Addiction Recovery and Hiring Decisions." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/7220.
Повний текст джерелаxu, kun. "Weibo Addiction in China: An Examination of the Relationships among Expected Outcomes, Weibo Usage, Deficient Self-regulation, and Weibo Addiction." Kent State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=kent1365048166.
Повний текст джерелаHellström, Isak. "The Institute for Screen Care and Marinebiological Research." Thesis, KTH, Arkitektur, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-262833.
Повний текст джерелаHirsch, Jameson K., Edward C. Chang, and Jessica K. Rabon. "A Positive Psychological Approach to Suicide: Theory, Research, and Prevention." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/5487.
Повний текст джерелаHowell, Simon Peter. "Force of habit the mystical foundations of the narcotic." Thesis, Rhodes University, 2012. http://hdl.handle.net/10962/d1002994.
Повний текст джерелаMast, Maria R. "Understanding Risk Factors in Opioid Addiction in Franklin County, Ohio." Franklin University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=frank1616006262553234.
Повний текст джерелаWebb, Jon R., Jameson K. Hirsch, and Loren Toussaint. "Forgiveness as a Positive Psychotherapy for Addiction and Suicide: Theory, Research, and Practice." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/666.
Повний текст джерелаLeonard, Roger D., Andrea D. Clements, and Becky Haas. "Panel: Holy Friendship - A Biblical Response to Pain and Addiction." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/7226.
Повний текст джерелаWahl, Troy Andrew. "Developing Thyronamine Analog Pharmaceuticals Targeting TAAR1 to Treat Methamphetamine Addiction." PDXScholar, 2013. https://pdxscholar.library.pdx.edu/open_access_etds/1109.
Повний текст джерелаPovozhaev, Lea M. "Addiction Rhetoric: Conceptual Metaphors in Conversational Illness Narratives." Kent State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=kent1406720653.
Повний текст джерелаStone, J. E., and Andrea D. Clements. "Research and Innovation: Let the Buyer Beware." Digital Commons @ East Tennessee State University, 1998. https://dc.etsu.edu/etsu-works/7216.
Повний текст джерелаWood, Leslie L. ""Everything I Did in Addiction, I'm Pretty Much the Opposite Now": Recovery Capital and Pathways to Recovery from Opiate Addiction." Kent State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=kent1594640821872756.
Повний текст джерелаSchlosser, Allison V. "Subjectivity and Moral Personhood: An Ethnography of Addiction Treatment in the United States." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1528722783811988.
Повний текст джерелаClements, Andrea D. "Cortisol Measurement in Developmental Research: Where Do We Go From Here?" Digital Commons @ East Tennessee State University, 2013. https://doi.org/10.1002/dev.21025.
Повний текст джерелаRuvalcaba, Socorro Maria, and Lupe Ayon Perez. "A qualitative research study on aging Latino substance abusers." CSUSB ScholarWorks, 1994. https://scholarworks.lib.csusb.edu/etd-project/889.
Повний текст джерелаClements, Andrea D. "Students’ Use of Email for Instructor Contact in Web-Enhanced and Non-Web-Enhanced College Courses." Digital Commons @ East Tennessee State University, 2001. https://dc.etsu.edu/etsu-works/7309.
Повний текст джерелаCyphers, Natalie, and Andrea D. Clements. "Religious Surrender and Attendance Satisfaction Scale: Validation of an Instrument for Healthcare Practice and Research." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/7251.
Повний текст джерелаClements, Andrea D. "The Completeness of Maternity and Premature Infants’ Medical Charts: Implications for Chart-Based Research Studies." Digital Commons @ East Tennessee State University, 1999. https://dc.etsu.edu/etsu-works/7314.
Повний текст джерелаMaartens, Pieter Johann. "Investigating the effects of nicotine on the male reproductive system." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/85759.
Повний текст джерелаENGLISH ABSTRACT: Much has been documented about the detrimental effects of adverse lifestyle factor exposure on the body. Exposure to factors, such as cigarette smoke, have proved to not only be a burden on global health and economy, but have also led to growing concerns about effects on systemic functions such as reproduction. The aim of the present study was to determine the effects of in utero and in vitro nicotine exposure on spermatozoal function and the antioxidant enzyme activity and lipid peroxidation (LPO) status of the male reproductive system. A better understanding of this process is necessary to combat the respective burdens of smoking and male infertility and for the prospective development of treatment strategies. Two experimental models were employed: Wistar rats were exposed to nicotine in utero while human and rat spermatozoa were exposed to nicotine in vitro. In utero studies were achieved by selecting healthy pregnant rats and treating them with 1 mg/kg-bodyweight/day nicotine or 1 ml/kg-bodyweight/day 0.85% physiologic saline throughout gestation and lactation. Male rat pups were selected and sacrificed at each of the following age groups (n=6): 42 days, 84 days and 168 days old. The pups were only exposed to the treatment/saline via placental uptake or lactation. Biochemical analyses of the tissue comprised of measurement of LPO and antioxidant enzyme activity. Results indicated a significant association of maternal nicotine exposure to decreased levels of primary antioxidant enzymes in rat testes. Of particular note was the observation that the treatment group, of which each of the respective antioxidant enzyme levels were significantly less than the control group, was the oldest (d168) rat group. In vitro studies were achieved by collecting sperm samples from healthy human donors (n=12), healthy rats (n=6) and obese rats (n=6). Samples were washed and exposed to different concentrations of high levels of nicotine (Control, 0.1mM, 1mM, 5mM, 10mM) in vitro. Semen parameters such as motility, viability and acrosome reaction were monitored at different time points (30min, 60min, 120min, 180min). Results revealed increasing in vitro nicotine concentrations were associated with decreased viability and acrosomal status of human spermatozoa and decreased progressive motility and viability of rat spermatozoa. Obesity was also associated with decreases in progressive motility and viability of rat spermatozoa. These results indicate that the acute in vitro exposure of spermatozoa to high levels of nicotine could adversely affect semen quality and may be an additive factor to the impediment of male fertility. In utero results reveal maternal nicotine exposure adversely affects male fertility in later life and seems to elicit more detrimental effects on the reproductive system than that of direct nicotine exposure to spermatozoa. Obesity also inhibits parameters of male fertility and these effects are exacerbated by nicotine exposure. The authors believe these adverse effects on the reproductive system to be related to an increased activation of leukocytes, excess production in reactive oxygen species (ROS) and consequent onset of oxidative stress (OS). Nevertheless this study agrees with other studies that nicotine exposure may be an additive factor to the impediment of male fertility.
AFRIKAANSE OPSOMMING: Daar is reeds baie bekend oor die moontlik newe effekte vir die liggaam wat met ‘n ongesonde lewenstyl gepaard gaan. Menslike blootstelling aan sulke faktore, soos sigaret rook, is wêreldwyd ‘n las vir gesondheid en ekonomie en het gelei tot geweldige kommer onder navorsers oor die moontlike komplikasies vir liggaamlike funksies soos voortplanting. Die doel van die betrokke projek was om die effekte van in utero en in vivo nikotien blootstelling op die antioksiderende ensiem aktiwiteit en lipied peroksidasie status van reproduktiewe weefsel en die funksionele parameters van spermatozoa te bepaal. ‘n Beter begrip van hierdie proses is noodsaaklik om die las van rook en vetsug teen te werk en vir die moontlike ontwikkeling van behandelingsstrategieë. Twee eksperimentele modelle is ontwerp: Wistar rotte is in utero blootgestel aan nikotien terwyl mens- en rot- spermatosoë ook in vitro aan nikotien blootgestel is. Vir die in utero studie is gesonde dragtige rotte gedurende swangerskap en laktasie met 1 mg/kgliggaamsgewig/ dag nikotien of 1 ml/kg-liggaamsgewig/dag 0.85% fisiologiese soutoplossing behandel. Manlike welpies is gekies en geoffer op elk van die volgende ouderdomme (n=6): 42 dae, 84 dae en 168 dae. Die welpies is slegs aan nikotien blootgestel deur plasentale opname en laktasie. Biochemiese analise van die testikulêre weefsel het ‘n beduidende assosiasie getoon tussen maternale nikotien blootstelling en verminderde vlakke van die primêre antioksiderende ensieme. Die 168 dag oue groep het ‘n merkbare vermindering getoon tussen kontrole en nikotien weefsel vir elk van die antioksiderende ensieme. Vir die in vitro studie is sperm monsters verkry vanaf gesonde mans (n=12), gesonde rotte (n=6) en vet rotte (n=6). Monsters is gewas en in vitro blootgestel aan verskeie hoë vlakke van nikotien (kontrole, 0.1mM, 1mM, 5mM, 10mM). Seminale parameters soos motiliteit, lewensvatbaarheid en akrosoom status is by verskei tydpunte gemeet (30min, 60min, 120min, 180min). Dit blyk dat verhoging in in vitro nikotien konsentrasies verband hou met verlaagde lewensvatbaarheid en akrosoom status van menslike spermatosoë en verlaagde progressiewe motilteit en lewensvatbaarheid van rot spermatosoë. Vetsug is ook geassosieer met verlagings in progressiewe beweeglikheid en lewensvatbaarheid van rot spermatosoë. In utero resultate openbaar dat maternale nikotien blootstelling manlike vrugbaarheid nadelig beïnvloed in latere lewe en blyk dat dit meer van ‘n nadelige uitwerking op die voortplantingstelsel het as dié van direkte nikotien blootstelling aan spermatosoë. In vitro blootstelling van spermatosoë aan hoë vlakke van nikotien, het wel ook semen kwaliteit nadelig beïnvloed. Vetsug inhibeer ook manlike vrugbaarheids parameters en hierdie effek word vererger deur nikotien blootstelling. Die outeure glo dat hierdie nadelige uitwerking op die voortplantingstelsel verband hou met 'n verhoogde aktivering van leukosiete, oortollige produksie van reaktiewe suurstof spesies en die gevolglike aanvang van oksidatiewe stres bevorder. Hierdie studie stem wel ooreen met ander studies wat nikotien blootstelling bestempel as ‘n bydraende faktor tot die struikelblok van manlike onvrugbaarheid.
Harry Crossley Foundation (South Africa)
Clements, Andrea D., and P. W. Myrick. "Requirements for Education on the Protection of Human Research Subjects: Implications for Educational Researchers." Digital Commons @ East Tennessee State University, 2002. https://dc.etsu.edu/etsu-works/7213.
Повний текст джерелаClements, Andrea D. "Requirements for Training in the Ethical Treatment of Human Research Subjects: Implications for Educational Researchers." Digital Commons @ East Tennessee State University, 2003. https://dc.etsu.edu/etsu-works/7300.
Повний текст джерелаClements, Andrea D. "Requirements for Training in the Ethical Treatment of Human Research Subjects: Implications for Educational Researchers." Digital Commons @ East Tennessee State University, 2002. https://dc.etsu.edu/etsu-works/7301.
Повний текст джерелаIrvin, Miriam, and Wilma Shepard. "A qualitative research study on fetal alcohol syndrome." CSUSB ScholarWorks, 1995. https://scholarworks.lib.csusb.edu/etd-project/978.
Повний текст джерелаClements, Andrea D. "Homeschooling." Digital Commons @ East Tennessee State University, 2008. https://dc.etsu.edu/etsu-works/7209.
Повний текст джерелаClements, Andrea D. "Satisfaction With Religious Commitment: Assessment of Readiness for Enhanced Religiosity." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/7252.
Повний текст джерелаClements, Andrea D. "Variety Of Teaching Methodologies Used By Homeschoolers: Case Studies Of Three Homeschooling Families." Digital Commons @ East Tennessee State University, 2002. https://dc.etsu.edu/etsu-works/7306.
Повний текст джерелаClements, Andrea D., G. Marion, C. Blankenship, and C. Burkitt. "Education 2000: Improving Technology and Professional Development--A Five-County Consortium." Digital Commons @ East Tennessee State University, 1996. https://dc.etsu.edu/etsu-works/7319.
Повний текст джерелаClements, Andrea D., and L. Rothenberg. "The Relationship Among Item Complexity, Item Format, and Test Length: Implications for Reliability." Digital Commons @ East Tennessee State University, 1996. https://dc.etsu.edu/etsu-works/7322.
Повний текст джерелаMoyer, Robert A. "Exploration of Functional Genetic Variants in Candidate Genes for Psychiatric Disorders." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1283184584.
Повний текст джерелаLaForge, Karl Steven. "Preproenkephalin Gene and mRNA : Studies of Structure, Function, Cocaine Responses in an Animal Model, and Genetic Association with Human Opiate Addiction." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4013.
Повний текст джерелаPack, Robert P., and Stephanie M. Mathis. "Prescription Drug Abuse: Responding with Research and Promoting Evidence-Based Practice." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/3203.
Повний текст джерелаWenders, John T., and Andrea D. Clements. "Homeschooling in Nevada: The Budgetary Impact." Digital Commons @ East Tennessee State University, 2005. https://dc.etsu.edu/etsu-works/7211.
Повний текст джерелаNewbill, S. L., and Andrea D. Clements. "Developing an Identity of Third-Graders." Digital Commons @ East Tennessee State University, 2000. https://dc.etsu.edu/etsu-works/7214.
Повний текст джерелаChildress, Lawrence D., and Andrea D. Clements. "Shifts in Ritual Response to Loss Due to Death: An Assessment of Funeral Service Mourning Trends over Time." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/7247.
Повний текст джерелаLambert, Jessica L., and Andrea D. Clements. "Lived Experiences of Formerly Incarcerated Adults Traveling on the Road to Rehabilitation." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/7255.
Повний текст джерелаClements, Andrea D., Natalie A. Cyphers, and Lawrence D. Childress. "Is Experimentally Increasing Religiosity Taboo?" Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/7258.
Повний текст джерелаClements, Andrea D., and Anna V. Ermakova. "Religious Commitment Predicts Lower Incidence of Preterm Birth in Rural Appalachian Women." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/etsu-works/7271.
Повний текст джерелаDixon, Wallace E. Jr, B. J. Salley, Andrea D. Clements, and J. Gorneiwicz. "Temperament, Distraction, and Learning in Toddlerhood." Digital Commons @ East Tennessee State University, 2006. https://dc.etsu.edu/etsu-works/7293.
Повний текст джерелаClements, Andrea D. "Variations in ADHD Diagnosis and Medication Prescription by Physicians in Southern Appalachia." Digital Commons @ East Tennessee State University, 2005. https://dc.etsu.edu/etsu-works/7297.
Повний текст джерелаClements, Andrea D. "Attention Deficit Hyperactivity Disorder (ADHD): Variations in Diagnostic Criteria and Medication Prescription by Physicians in Southern Appalachia." Digital Commons @ East Tennessee State University, 2004. https://dc.etsu.edu/etsu-works/7298.
Повний текст джерелаSnider, J. Blake, and Andrea D. Clements. "Late Adolescent Perceptions of Parent Religiosity and Parenting Processes." Digital Commons @ East Tennessee State University, 2004. https://dc.etsu.edu/etsu-works/7299.
Повний текст джерелаClements, Andrea D. "Problems (and solutions) in Online Teaching II." Digital Commons @ East Tennessee State University, 2002. https://dc.etsu.edu/etsu-works/7307.
Повний текст джерелаClements, Andrea D., and Steve Cockerham. "Problems (and solutions) in Online Teaching." Digital Commons @ East Tennessee State University, 2001. https://dc.etsu.edu/etsu-works/7310.
Повний текст джерелаClements, Andrea D., J. Charlesworth, and L. Rothenberg. "Increasing Active Learning, Higher-Order Thinking, and Relevance/Meaningfulness in the University Classroom." Digital Commons @ East Tennessee State University, 1997. https://dc.etsu.edu/etsu-works/7317.
Повний текст джерелаClements, Andrea D., and Natalie Cyphers. "Church Attendance and Intrinsic Religiosity Predict a Lower Likelihood of Hypertension in 18 to 60 Year Olds." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/7244.
Повний текст джерелаPugh, Kelley, Andrea D. Clements, and Jameson K. Hirsch. "The Surrender to God Scale: Psychometric Validation and Psychological Correlates." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/7236.
Повний текст джерелаHaas, Becky, and Andrea D. Clements. "Building a Trauma Informed System of Care." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/7197.
Повний текст джерелаScary, Thomas. "American Ignominy: The Incarceration of the Mentally Ill." Master's thesis, Temple University Libraries, 2018. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/501251.
Повний текст джерелаM.A.
Prisons and jails have become the de facto psychiatric hospitals of the twenty-first century. In the wake of deinstitutionalization, as mental healthcare transitioned to a community-based model, many patients with mental illness found themselves incarcerated rather than hospitalized. Strict drug laws combined with the current opioid epidemic are now forcing the government to consider treatment over punishment, lest the prison populations continue to swell. It is time to strongly consider using the involuntary commitment for severe cases of substance abuse if the patient is unwilling to undergo rehabilitation. Refusing to wait for the federal government to act, cities and states around the nation have begun to experiment with novel solutions to these issues, working within the framework of the prison system to achieve better outcomes.
Temple University--Theses