Дисертації з теми "ABA1"
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Ghassemian, Majid. "Genetic and molecular interactors of ABA insensitive1 gene (abi1) of Arabidopsis thaliana." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0025/NQ49826.pdf.
Повний текст джерелаVan, Thielen Nocha. "Genetic interactions between the ABA insensitive mutant, abi1-1, and the ABA supersensitive mutant, era1-4, in Arabidopsis thaliana." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0001/MQ45891.pdf.
Повний текст джерелаJuan, Emanuel Enrique. "ABAX S.R.L." Universidad Nacional de Cuyo. Facultad de Ingeniería, 2018. http://bdigital.uncu.edu.ar/10952.
Повний текст джерелаFil: Juan, Emanuel Enrique. Universidad Nacional de Cuyo. Facultad de Ingeniería.
Dasgupta, Yashodhara. "NORMAL ABL1 IS A TUMOR SUPPRESSOR AND THERAPEUTIC TARGET IN BCR-ABL1-POSITIVE LEUKEMIAS." Diss., Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/239008.
Повний текст джерелаPh.D.
BCR-ABL1 results from t(9;22)(q34;q11) reciprocal translocation resulting in BCR-ABL1 kinase expression, initiating chronic myeloid leukemia in chronic phase (CML-CP). At the initial stages of CML-CP both oncogenic BCR-ABL1 kinase and normal ABL1 kinase are expressed, however, loss of ABL1 kinase expression in CML-CP can result from an interstitial deletion in the normal chromosome 9 [del(9q34)] which may be combined with the transcriptional silencing of the alternative ABL1 promoter within the translocation eventually leading to disease progression and drug resistance. We found that BCR-ABL1 Abl1-/- cells generated a CML-blast phase (BP)-like disease phenotype in NOD-SCID mice compared to the BCR-ABL1 Abl1+/+ cells. To determine the mechanisms responsible for blastic transformation of BCR-ABL1 Abl1-/- cells, we examined the role of ABL1 in proliferation, differentiation, apoptosis, genomic instability, and stemness. The presence of ABL1 inhibited proliferation in BCR-ABL1 cells as BCR-ABL1 Abl1-/- cells had higher clonogenic activity and proliferative rate compared to their wild-type counterparts. ABL1 is essential for myeloid differentiation since BCR-ABL1 Abl1-/- cells showed an immature blast phenotype when stained with Wright-Giemsa and myeloid differentiation markers Gr-1 and CD11b. ABL1 promoted apoptosis in response to genotoxic stress as revealed by reduced clonogenicity and expression of p53, phosphoserine-15 p53 and activated caspase 3 in BCR-ABL1 Abl1+/+ compared to knock-out cells. Although the absence of ABL1 did not enhance ROS and oxidative DNA damage, it appears that an impaired DNA damage response may be responsible for higher chromosome numbers and an accumulation of high numbers of chromosomal aberrations in BCR-ABL1 Abl1-/- cells. We detected an expansion of Lin-c-Kit+Sca-1+ leukemia stem cells (LSCs) in BCR-ABL1 Abl1-/- cells compared to BCR-ABL1 Abl1+/+ or non-transformed counterparts; among the LSCs, there was a higher percentage of CD34-Flt3- long-term and CD34+Flt3- short-term stem cells. These results showed that ABL1 is involved in regulating the LSC compartment in BCR-ABL1 cells. DNA microarray analysis revealed changes in mRNA levels of several genes involved in proliferation, myeloid differentiation, apoptosis, DNA damage response and `stemness' in BCR-ABL1 Abl1-/- cells in comparison to BCR-ABL1 Abl1+/+ cells. Together, these results demonstrate a critical role of ABL1 as a tumor suppressor in BCR-ABL1-induced leukemia, prolonging survival in mice by suppressing proliferation and expansion of LSC, inducing myeloid differentiation, apoptosis and DNA damage response in BCR-ABL1 cells. Loss of ABL1 was also found to contribute to Imatinib resistance in BCR-ABL1 cells. Moreover, we hypothesized that enhancement of the tumor-suppressor function of ABL1 may have a significant impact on CML treatment. A small molecule activator of ABL1 kinase, 5-(1,3-diaryl-1H-pyrazol-4-yl)hydantoin (DPH), have been reported to interact with the myristoyl-binding site of ABL1 and destabilize the bent conformation of the á1 helix, thereby preventing the auto-inhibitory conformation. Western blot analysis revealed partially restored activation of ABL1 kinase when Imatinib-treated cells were incubated with DPH. DPH along with Imatinib was found to inhibit viability of BCR-ABL1 Abl1+/+ cells but not BCR-ABL1 Abl1-/- cells demonstrating its ABL1-specific mode of action. DPH when used in combination with tyrosine kinase inhibitors such as Imatinib and Ponatinib inhibited growth of CML CD34+ cells, Philadelphia chromosome-positive B-Acute Lymphoblastic Leukemia (Ph+B-ALL) cells and relapsed Ph+B-ALL cells harboring T315I mutation without affecting normal counterparts. A similar inhibitory effect was observed when TEL-ABL1-expressing cell lines and NUP214-ABL1-expressing murine bone marrow cells were treated with DPH and Imatinib, as well as Acute Myeloid Leukemia (AML) cells expressing FLT3-ITD mutation when treated with DPH in combination with AC220 which is the FLT3-ITD inhibitor. In summary, ABL1 is a potential tumor-suppressor in BCR-ABL1-induced leukemia and stimulation of its function may play a significant role in the development of novel therapeutic strategies for CML and other Fusion Tyrosine Kinase (FTK)-mediated hematologic malignancies.
Temple University--Theses
Kang, Martin Hubert. "Post-transcriptional regulation of ABCA1." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43655.
Повний текст джерелаWilliams, Jeremy Hugh. "Monitoring the condition of semi-natural vegetation : the application of remote sensing and geographical information systems (GIS)." Thesis, Bangor University, 1992. https://research.bangor.ac.uk/portal/en/theses/monitoring-the-condition-of-seminatural-vegetation--the-application-of-remote-sensing-and-geographical-information-systems-gis(c90702cb-be4f-454f-aba1-1c74484c0093).html.
Повний текст джерелаDawalibi, Paul. "L'amour comme aban-don de soi." Paris 4, 2008. http://www.theses.paris-sorbonne.fr/these_dawalibi/paris4/2008/these_dawalibi/html/index-frames.html.
Повний текст джерелаBy the event of the loss of one, the loss of the intimacy of one, the self leash-being-taken according to the requirements of a native abnegation or renunciation in what made begin in her the immoderation, the nonlimit and the increasing of what has already begun in her since her birth. So, any resemblance holds in her its difference, any appropriation exposes it self to a change, any power breaks, any pride alienates and any narcissism suffocate or suppresses under the charm of its own beauty. And because the limit of one "at home" is by definition non-familiar, the paradox of the borders, so produced, will distort (alter) at least the power to be one and even the meaning of an "at home" ontological. From then on, get lost it is to let the self-abnegation make the native come in itself, it is to be originally according to the arrival of the event of its birth, of the resumption of the donation native of one. Only the arrival of what creates the self originally makes possible to let-be-abandoned by one. Only the arrival of Love makes possible the native donation as the self-abnegation
Chambenoit, Olivier. "ABCA1 et l'homéostasie du cholestérol cellulaire." Aix-Marseille 2, 2003. http://www.theses.fr/2003AIX22023.
Повний текст джерелаDawalibi, Paul Marion Jean-Luc Greisch Jean. "L'amour comme aban-don de soi." Paris : Université Paris Sorbonne - Paris IV, 2008. http://www.theses.paris4.sorbonne.fr/these_dawalibi/paris4/2008/these_dawalibi/html/index-frames.html.
Повний текст джерелаBélair, Caroline. "Ab1-42 and Ab1-40 induce tau phosphorylation in human neurons." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=27279.
Повний текст джерелаWe incubated the human fetal primary neuron cultures with A$ beta sb{1-40}$ and A$ beta sb{1-42}$ (100nM). The western blots show that serine 202 epitope of tau protein is phosphorylated in a cyclic manner. With the tau phosphorylation assay, we showed that A$ beta sb{1-40}$ and A$ beta sb{1-42}$ activate one or more protein kinase(s) able to phosphorylate tau protein and more specifically the serine 202 epitope.
We conclude that pathological concentrations of aggregated peptides A$ beta sb{1-40}$ and A$ beta sb{1-42}$ activate protein kinases which induce the phosphorylation of tau protein and serine 202 epitope.
Santiago, Cuéllar Julia. "Structural insights into ABA perception and signalling: structure of ABA receptor PYR1." Doctoral thesis, Universitat Politècnica de València, 2011. http://hdl.handle.net/10251/13260.
Повний текст джерелаSantiago Cuéllar, J. (2011). Structural insights into ABA perception and signalling: structure of ABA receptor PYR1 [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/13260
Palancia
Alfaro, Alicia E. "Prehispanic Water Management at Takalik Abaj, Guatemala." Thesis, University of South Florida, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=1547711.
Повний текст джерелаLand and water use at archaeological sites is a growing field of study within Mesoamerican archaeology. In Mesoamerica, similar to elsewhere in the world, landscapes were settled based partially upon the characteristics of the environment and the types of food and water resources available. Across Mesoamerica, landscape concepts were also important to religious beliefs and ritual activity in a manner that may have had the potential to influence the power dynamics of a site. This thesis focuses on the management of water at the site of Takalik Abaj in Guatemala during the Middle to Late Preclassic periods (c. 1000 B.C. - A.D. 250) in order to analyze potential ritual and political functions of the water management system. Using spatial data within GIS, this thesis examines the flow of water across the site as directed by its topographical features. The archaeological record of Takalik Abaj and comparisons to water management systems at other Mesoamerican sites are also used to investigate the functions of the water management system. Thesis findings suggest that the water management system of Takalik Abaj was multi-faceted and that ritual functions tied to the control of water may have contributed to the identities and power of the elite.
Sealy, Ian Malcolm. "Expression of wild-type and mutated ABP1." Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263823.
Повний текст джерелаGarcia, Rosangela Silveira. "Entre abas : processos de enunciação em rede." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2018. http://hdl.handle.net/10183/180531.
Повний текст джерелаThe navigation tab is a universe of enunciation and discursive constitution, scenery of the subject's acting and being in different social spaces in the digital world. Territorialisation in the tabs constitutes the universe of ethical and political relations emerging from social interactions. Starting from this proposition, we present a study that aims to investigate the processes of enunciation that are established in the digital world, aiming to analyze the ways in which educators enunciate and assume socio-enunciative positions in the tabs that territorialize. Methodologically, while essentially focusing on dialogism as a philosophical-enunciative position, this research makes, during its course, certain approximations of the assumptions of the area of study of Computer-Mediated Communication; of assumptions of the science of the networks and of the SNA (Social Networks Analysis). The data analyzed are the result of the emergent statements of the educators' discourse, coming from virtual communities on the social networking site Facebook. The statements are considered to be related to their responsive connections with other statements that precede and / or follow them, and in the correlation with the spaces where they are produced. As a way to form the representative network of these relations, and to analyze them from their degree of connection, Pajek software - open source software that allows visualization and analysis of large networks - was adopted, and, as a metric, centrality of the constituents of the enunciative network was analyzed The enunciative network formed was analyzed in two perspectives: SNA, and Bakhtinian assumptions. In our trajectory the main discoveries led us to realize that the discursive process, in its configuration, that is, in materialization through statements, has effects of the interface, as well as its impact. That the statement produced by the educators has an accentuated autobiographical character and the dialogic relations are established and circulate through different spaces and its linkage derives from the actions of comment and enjoyment. In the context of socio-enunciative positions, it has been identified that they are multiple and do not present themselves in an alternate way, nor do they form as isolated and independent parts of a whole. The socio-enunciative positions, in this case, are instituting provisional finishes for the yourself discursive. This study understands that it can contribute to the field of research in human sciences, and to the study of the processes of enunciation in the digital context, contemplating one of the directives of the research line Digital Interfaces in Education, Art, Language and Cognition of the Graduate Program in Computer Science in Education of the Federal University of Rio Grande do Sul (UFRGS), whose objective is to investigate the effects of digital interfaces in different empirical fields.
La solapa de navegación es un universo de enunciación y constitución discursiva, escenario del actuar y estar del sujeto en distintos espacios sociales en el mundo digital. La territorialización en las alas constituye el universo de las relaciones éticas y políticas emergentes de las interacciones sociales. A partir de esta proposición, traemos un estudio que tiene como meta investigar los procesos de enunciación que se establecen en el mundo digital, buscando analizar las formas como educadores enuncian y asumen posiciones socio-enunciativas en las abas que territorializan. Metodológicamente, aunque, esencialmente, se centra en el dialogismo como posición filosófica-enunciativa, esta investigación hace, durante su recorrido, ciertas aproximaciones de los presupuestos del área de estudios de la Comunicación Mediada por el Ordenador; de los supuestos de la ciencia de las redes y de la ARS (Análisis de Redes Sociales). Los datos analizados son resultado de los enunciados emergentes del discurso de educadores, provenientes de comunidades virtuales en el sitio de la red social Facebook. Los enunciados se consideran relacionados con sus conexiones responsivas con otros enunciados que los anteceden y / o los siguen, y en la correlación con los espacios donde se producen. Como forma de constituir la red representativa de estas relaciones, y analizarlas a partir de su grado de conexión, se adoptó el software Pajek - software de código abierto - que posibilita visualización y análisis de grandes redes, y cómo métrica se analizó centralidad de los constituyentes de la red enunciativa La red enunciativa formada fue analizada en dos perspectivas: de la ARS, y de supuestos bakhtinianos. En nuestro trayecto los principales descubrimientos nos llevaron a percibir que el proceso discursivo, en su configuración, o sea, en la materialización por medio de enunciados, sufre efectos de la interfaz, así como también le causa impacto. Que el enunciado producido por los educadores tiene carácter autobiográfico acentuado y las relaciones dialógicas se establecen y circulan por distintos espacios, siendo su encadenamiento resultante de las acciones de comentar y de disfrutar. En el ámbito de las posiciones socio-enunciativas, se identificó que son múltiples y no se presentan de modo alternado, tampoco se configuran como partes aisladas e independientes de un todo. Las posiciones socio-enunciativas, en este caso, van instituyendo acabados provisionales al mismo discursivo. Este estudio comprende que puede aportar contribuciones al campo de las investigaciones en ciencias humanas, ya los estudios de los procesos de enunciación en el contexto digital; que contempla uno de los direccionamientos de la línea de investigación Interfaces Digitales en Educación, Arte, Lenguaje y Cognición del Programa de Postgrado en Informática en la Educación de la Universidad Federal de Rio Grande do Sul (UFRGS) que tiene como objetivo investigar los efectos de las interfaces digitales en diferentes campos empíricos.
HAMON, YANNICK. "Abc1, de la structure a la fonction." Aix-Marseille 2, 1999. http://www.theses.fr/1999AIX22067.
Повний текст джерелаChaabane, Khalid. "Bilan énergétique de Abax ater (Villers) (Coleoptera, Carabidae)." Doctoral thesis, Universite Libre de Bruxelles, 1995. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/212613.
Повний текст джерелаNagao, Kojiro. "Mechanism of high-density lipoprotein formation by ABCA1." Kyoto University, 2010. http://hdl.handle.net/2433/120486.
Повний текст джерела0048
新制・課程博士
博士(農学)
甲第15443号
農博第1828号
新制||農||981(附属図書館)
学位論文||H22||N4542(農学部図書室)
27921
京都大学大学院農学研究科応用生命科学専攻
(主査)教授 植田 和光, 教授 間藤 徹, 教授 阪井 康能
学位規則第4条第1項該当
Nandi, Shilpi. "The involvement of membrane vesiculation in ABCA1 mediated efflux." Thesis, University of Ottawa (Canada), 2007. http://hdl.handle.net/10393/27897.
Повний текст джерелаRogers, Jennifer Jacqueline Mavis. "Mutational analysis of the maize auxin binding protein, ABP1." Thesis, University of the West of England, Bristol, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249341.
Повний текст джерелаAlohaly, Manar Fathi. "Frameworks for Attribute-Based Access Control (ABAC) Policy Engineering." Thesis, University of North Texas, 2020. https://digital.library.unt.edu/ark:/67531/metadc1707241/.
Повний текст джерелаSenger, Sigrun. "Einfluss von ABA auf frühe Embryogeneseprozesse." [S.l. : s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=962324604.
Повний текст джерелаRoyle, Paul. "Regulation of the ABA biosynthetic pathway." Thesis, University of Nottingham, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415501.
Повний текст джерелаCyras, Kristijonas. "ABA+ : assumption-based argumentation with preferences." Thesis, Imperial College London, 2017. http://hdl.handle.net/10044/1/58340.
Повний текст джерелаAlmehmady, Alshaimaa. "ABA triblock copolymer flower micelles formulations." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/50848/.
Повний текст джерелаKaul, Sonu. "Uptake, transport and bioactivity of exogenously applied ABA and ABA analogues in white spruce and wheat seedlings." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ36644.pdf.
Повний текст джерелаConforti, Evandro 1947. "Antena a guia cilindrico-circular comterminação em flange conica." [s.n.], 1987. http://repositorio.unicamp.br/jspui/handle/REPOSIP/261303.
Повний текст джерелаMade available in DSpace on 2018-07-14T06:45:31Z (GMT). No. of bitstreams: 1 Conforti_Evandro_LD.pdf: 1411719 bytes, checksum: f7e679b0f5365ad3d77069e8c1581463 (MD5) Previous issue date: 1987
Resumo: Não informado
Abstract: Not informed
Tese (livre-docencia) - Univer
Livre-Docente em Engenharia Eletrica
Abah, Obinna [Verfasser], and Eric [Akademischer Betreuer] Lutz. "Quantum machines at the nanoscale / Obinna Abah. Gutachter: Eric Lutz." Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 2015. http://d-nb.info/1077914342/34.
Повний текст джерелаJennelle, Lucas Trent. "Contribution of Calnexin to HIV-1 Nef effects on ABCA1." Thesis, The George Washington University, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=3557581.
Повний текст джерелаHIV-infected patients are at increased risk of developing atherosclerosis, in part due to an altered HDL profile exacerbated by downmodulation and impairment of ATP-Binding Cassette Transporter A1 (ABCA1) activity by the HIV-1 protein Nef. Nef has been shown to increase delivery of cholesterol to lipid rafts, sites of viral assembly and egress, by inhibition of ABCA1 cholesterol efflux functionality and reduction of ABCA1 protein levels through lysosomal degradation. Important mechanistic details of ABCA1 inactivation and degradation by Nef, and whether these two processes are intimately linked or separable are still to be defined. The studies presented here were designed to identify cellular co-factors for ABCA1-mediated cholesterol efflux that may be targeted by Nef to achieve ABCA1 inactivation. In these studies, a novel cellular factor, the ER-resident lectin chaperone calnexin, was shown to be involved in a physical interaction with ABCA1 that is disrupted by Nef. Nef was found to bind and redistribute calnexin and reduce binding and co-localization of ABCA1 with calnexin. In vitro knockdown of calnexin via RNAi reproduced several previously described biochemical effects of Nef, including redistribution of ABCA1, increased ABCA1 membrane localization, and reduced ABCA1 recycling. Importantly, knockdown of calnexin also resulted in reduced ABCA1-mediated cholesterol efflux, but without the Nef-mediated reduction in ABCA1 protein levels, suggesting that Nef utilizes a bipartite mechanism to inactivate and degrade ABCA1 and that these functions may be separable. Despite the lack of effect of calnexin knockdown on ABCA1 protein levels, interference with the ABCA1-calnexin interaction was critical for Nef-mediated functional impairment of ABCA1. This was shown with a Nef mutant defective in interaction with calnexin which was incapable of preventing ABCA1-calnexin interaction and was also defective in impairing ABCA1-mediated cholesterol efflux activity. Thus, these studies identified a novel mechanism by which HIV-1 Nef impairs functional activity of cholesterol transporter ABCA1 by blocking its interaction with calnexin. Calnexin acts as an ABCA1 functional chaperone, limiting total and cell surface ABCA1 expression while increasing ABCA1-mediated cholesterol efflux. Combined with the demonstration that Nef increases delivery of ABCA1 to lysosomes, these results suggest the Nef-mediated impairment of ABCA1 function involves reduced interaction with calnexin followed by delivery of ABCA1 to lysosomes for degradation.
Hallasi, Cornejo Eduardo H., Cornejo Abel R. Hallasi, and Molina Rhafael Tinco. "Planeamiento estratégico de la Provincia de Padre Abad 2018-2027." Master's thesis, Pontificia Universidad Católica del Perú, 2017. http://tesis.pucp.edu.pe/repositorio/handle/123456789/9541.
Повний текст джерелаThe present thesis has the strategic plan approach for the province of Padre Abad located in the region of Ucayali with projection to 2027. The development of this thesis has permitted to construct a new vision that includes the development, the sustainability and the competitiveness of the Padre Abad province; providing progress and quality of life to its inhabitants through increased production of wood, tourism and agriculture. In the investigation made by the group, it was detected that this province has many advantages because it is in the Amazonian zone of Peru. Among the advantages that can be listed, are the wood production, tourism, agriculture, rivers, abundant natural resources, varied climates, etc. However, there is a lack of training and technology for farmers, producer of wood, tourism and other services. The Padre Abad province does not have all the basic services and infrastructure for the entire population, and it requires a majority participation by the government. The most important thing in this moment is to generate a culture of innovation, supported by technological development in order to capitalize on all activities. Therefore, to achieve the new vision, long-term objectives have been developed with their respective strategy which will be measured with short-term objectives. Likewise, compliance with the proposed policies is required for the strategies to function fully. It is important the synergy of all the stakeholders, within them are the citizens, the businessmen, the government; and the investors. Finally, it is proposed to deliver this thesis to the province of Padre Abad to serve as a tool for the achievement of its objectives, as well as deliver it to potential investors to make their investments in the different sectors that this province has
Tesis
Priori, Posada Giovanni F. "ABAD YUPANQUI, Samuel. Derecho Procesal Constitucional. Lima: Gaceta Jurídica, 2005." Pontificia Universidad Católica del Perú, 2005. http://repositorio.pucp.edu.pe/index/handle/123456789/116155.
Повний текст джерелаPatel, Dipesh C. "Glycaemic influences on the ATP-binding cassette transporter A1 (ABCA1)." Thesis, Imperial College London, 2010. http://hdl.handle.net/10044/1/6864.
Повний текст джерелаSymonds, Rachael Catherine. "The manipulation of the ABA biosynthetic pathway." Thesis, University of Nottingham, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410335.
Повний текст джерелаHellman, Mikael, and Ruin Alexis Kalingas. "ABA Stol : En kontorsstol för aktivitetsbaserade arbetsplatser." Thesis, KTH, Skolan för industriell teknik och management (ITM), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-282435.
Повний текст джерелаActivity-based workplace has come to stay in Swedish offices, although many do not like the new way of working there are many advantages for the companies. Work chairs are today made for a more traditional way of working and often have many and complicated settings. In a more mobile environment where people change chairs every day or even several times a day, not everyone adjust the chair properly, resulting in poor ergonomics. Because not everyone likes the new way of working, it sets higher demands on the interior to make it more personal and inviting. In this work, a new task chair has been developed with good ergonomics and clear adjustments, with back and seat of mesh. The work has also been in positioning the chair, creating guidelines for the design and an environmental strategy for manufacturing a chair that takes the environment into account. The positioning focused on activity-based workplaces since there are no chairs clearly aimed for these. The design guidelines have focused on three words neat, comfort and simple. It has been important that the chair is sober in an office landscape while it is inviting, comfortable and offers a personality for those who will use it. The guidelines have been exemplified with a final concept that shows a variant of how a finished chair could look. The ergonomics have been resolved with a synchronized knee joint. This is controlled by a gas spring and can be weight-adjusted with an eccentric wheel with six positions. In total, three adjustment options are available for the synchronous tongue, the weight adjustment as well as raising and lowering the chair. Great work has been in designing and verifying the synchronizing knee swing function and ergonomics. This was done using CAD and a physical prototype. The prototype shows that the desired movement and thus ergonomics can be achieved with the constructed synchronous knee swing. The environmental work has been focused on two parts. The more general is to follow the Svanenmärkningen rules, as it is best suited for office chairs. In addition to this, exploration has done how to design a chair in the best way so that a used chair can be easily renovated and cleaned to get "a second life". There a lot has come of robust mechanism that lasts a long time and an upholstery that is easy to change.
Grumelard, Julie. "Biomimetic superstructures from amphiphilic ABA-triblock copolymers /." Basel : [s.n.], 2005. http://edoc.unibas.ch/diss/DissB_7329.
Повний текст джерелаHa, Tracy. "The role of pathogen defense signaling components in ABA signal transduction and isolation of an ABA/C23 signaling mutant." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p1469579.
Повний текст джерелаTitle from first page of PDF file (viewed Oct. 15, 2009). Available via ProQuest Digital Dissertations. Includes bibliographical references (p. 67-76).
Hawkes, Neil. "Does teaching values improve the quality of education in primary schools? : a study about the impact of introducing values education in a primary school." Thesis, University of Oxford, 2005. https://ora.ox.ac.uk/objects/uuid:bdb77d49-ab71-4d2b-87eb-ffa040ade219.
Повний текст джерелаRoss, Jonathan E. "Peptidomimetic foldamers of β-secondary structural elements". Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:a44b48d0-59fa-4f28-abac-7b66b6391d6c.
Повний текст джерелаJohan, Filip Rindler Johan Filip. "Lower Semicontinuity and Young Measures for Integral Functionals with Linear Growth." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:c4736fa2-ab51-4cb7-b1d9-cbab0ede274b.
Повний текст джерелаLockyer, Anne. "Molecular and biological analysis of the putative Golgi mannosidase II and other enzymes involved in N-linked glycosation in Drosophila melanogaster." Thesis, University of Oxford, 1995. http://ora.ox.ac.uk/objects/uuid:c5f4bae1-5f4e-46a7-abae-51eeb8f73bbe.
Повний текст джерелаFreeman, Alexandra L. J. "Butterflies as signal receivers." Thesis, University of Oxford, 1998. http://ora.ox.ac.uk/objects/uuid:a441ad53-dba2-406a-ab71-466ac0831782.
Повний текст джерелаWilliams, Arthur Howard. "Adar yng ngwaith y Cywyddwyr." Thesis, Aberystwyth University, 2014. http://hdl.handle.net/2160/62c92587-ab31-4062-a7bf-9ff8af4060cb.
Повний текст джерелаRees, Matthew. "Faith-based political engagement at the sub-state level in the UK : the cases of Wales and Northern Ireland." Thesis, Aberystwyth University, 2016. http://hdl.handle.net/2160/3c947c1a-bce4-4b7e-abf1-d8c203da5add.
Повний текст джерелаSaitta, Evan. "The taphonomy of soft tissues and the evolution of feathers." Thesis, University of Bristol, 2019. http://hdl.handle.net/1983/4d80b879-abf1-41a5-8520-1c118e7d1a48.
Повний текст джерелаVasistha, Navneet A. "Role of Tbr2 in intermediate progenitors during cortical neurogenesis." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:cca66b37-145e-4212-ab01-0f11fe1c9be5.
Повний текст джерелаZiegler, Reuven. "Voting rights of recognised Geneva Convention refugees in their countries of asylum." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:b48689d0-d6f8-49fd-aba7-0cb7ca8e2f3a.
Повний текст джерелаBett, Douglas Robert. "The development of a fast intra-train beam-based feedback system capable of operating on the bunch trains of the International Linear Collider." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:a7bcc7fd-abb1-4b65-9fa1-9aacb825c7bc.
Повний текст джерелаStorey, Damien. "Mere appearances : appearance, belief, & desire in Plato's Protagoras, Gorgias, & Republic." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:b13abb0f-978d-4b70-ab01-7c5a4ef448a4.
Повний текст джерелаAmbrose, Timothy James William. "Serine hydrolase activity and roles for monoacylglycerol lipase in innate immunity and intestinal inflammation." Thesis, University of Oxford, 2018. http://ora.ox.ac.uk/objects/uuid:f7a12796-ae8f-4121-ab1a-26778261ac78.
Повний текст джерелаYang, Jinchao. "Development and application of bifunctional iminophosphorane organocatalysts." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:fa250f43-ab91-4aec-9fa3-f6ccdb444bb5.
Повний текст джерелаDaalder, Jurrit. "Straight from the Heartland : New Sincerity and the American Midwest." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:ac2cbe67-2938-4d60-ab41-30944cb6c4eb.
Повний текст джерела