Готові списки джерел за темами / A2BP1

Добірка наукової літератури з теми "A2BP1"

Автор: Grafiati
Опубліковано: 6 вересня 2023

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Статті в журналах з теми "A2BP1"

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Ma, L., R. L. Hanson, M. T. Traurig, Y. L. Muller, B. P. Kaur, J. M. Perez, D. Meyre, et al. "Evaluation of A2BP1 as an Obesity Gene." Diabetes 59, no. 11 (August 19, 2010): 2837–45. http://dx.doi.org/10.2337/db09-1604.

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Dong, Licai, Hao Yan, Xuebing Huang, Xiaofeng Hu, Yongfeng Yang, Cuicui Ma, Bo Du, et al. "A2BP1 gene polymorphisms association with olanzapine-induced weight gain." Pharmacological Research 99 (September 2015): 155–61. http://dx.doi.org/10.1016/j.phrs.2015.06.003.

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Kiehl, Tim-Rasmus, Hiroki Shibata, Tramy Vo, Duong P. Huynh, and Stefan-M. Pulst. "Identification and expression of a mouse ortholog of A2BP1." Mammalian Genome 12, no. 8 (August 2001): 595–601. http://dx.doi.org/10.1007/s00335-001-2056-4.

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4

Hamada, Nanako, Hidenori Ito, Ikuko Iwamoto, Makoto Mizuno, Rika Morishita, Yutaka Inaguma, Sachiyo Kawamoto, Hidenori Tabata, and Koh-ichi Nagata. "Biochemical and morphological characterization of A2BP1 in neuronal tissue." Journal of Neuroscience Research 91, no. 10 (August 6, 2013): 1303–11. http://dx.doi.org/10.1002/jnr.23266.

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Gehman, Lauren T., Peter Stoilov, Jamie Maguire, Andrey Damianov, Chia-Ho Lin, Lily Shiue, Manuel Ares, Istvan Mody, and Douglas L. Black. "The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain." Nature Genetics 43, no. 7 (May 29, 2011): 706–11. http://dx.doi.org/10.1038/ng.841.

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Joshita, Satoru, Takeji Umemura, Kaname Yoshizawa, Yoshihiko Katsuyama, Eiji Tanaka, and Masao Ota. "A2BP1 as a novel susceptible gene for primary biliary cirrhosis in Japanese patients." Human Immunology 71, no. 5 (May 2010): 520–24. http://dx.doi.org/10.1016/j.humimm.2010.02.009.

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Martin, Christa Lese, Jacqueline A. Duvall, Yesim Ilkin, Jason S. Simon, M. Gladys Arreaza, Kristin Wilkes, Ana Alvarez‐Retuerto, et al. "Cytogenetic and molecular characterization of A2BP1 / FOX1 as a candidate gene for autism." American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 144B, no. 7 (May 14, 2007): 869–76. http://dx.doi.org/10.1002/ajmg.b.30530.

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Guven-Ozkan, Tugba, Germain U. Busto, Soleil S. Schutte, Isaac Cervantes-Sandoval, Diane K. O’Dowd, and Ronald L. Davis. "MiR-980 Is a Memory Suppressor MicroRNA that Regulates the Autism-Susceptibility Gene A2bp1." Cell Reports 14, no. 7 (February 2016): 1698–709. http://dx.doi.org/10.1016/j.celrep.2016.01.040.

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Hammock, Elizabeth A. D., and Pat Levitt. "Developmental Expression Mapping of a Gene Implicated in Multiple Neurodevelopmental Disorders, A2bp1 (Fox1)." Developmental Neuroscience 33, no. 1 (2011): 64–74. http://dx.doi.org/10.1159/000323732.

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Chatterjee, A., S. Jana, and A. Bhattacharyya. "123P Stabilization of SDCBP oncoprotein and aiding breast cancer growth and metastasis: The role of A2BP1." Annals of Oncology 27 (December 2016): ix37. http://dx.doi.org/10.1016/s0923-7534(21)00282-9.

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Більше джерел

Дисертації з теми "A2BP1"

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Frese, Karen Sonia [Verfasser], and Thomas [Akademischer Betreuer] Wieland. "A2BP1-vermitteltes RNA-Spleißen ist essentiell für die kardiale Funktion im Zebrafisch / Karen Sonia Frese ; Betreuer: Thomas Wieland." Heidelberg : Universitätsbibliothek Heidelberg, 2013. http://d-nb.info/1177809818/34.

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Frese, Karen S. [Verfasser], and Thomas [Akademischer Betreuer] Wieland. "A2BP1-vermitteltes RNA-Spleißen ist essentiell für die kardiale Funktion im Zebrafisch / Karen Sonia Frese ; Betreuer: Thomas Wieland." Heidelberg : Universitätsbibliothek Heidelberg, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:16-heidok-157835.

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Hochheiser, Julia Verfasser], and Sönke [Akademischer Betreuer] [Behrends. "Untersuchungen zur Isoform a2b1 der NO-sensitiven Guanylat-Cyclase hinsichtlich ihrer subzellulären Lokalisation und möglicher Interaktionspartner / Julia Hochheiser ; Betreuer: Sönke Behrends." Braunschweig : Technische Universität Braunschweig, 2018. http://d-nb.info/1175814695/34.

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Peveler, Edward. "The supply of building materials to construction projects in Roman Oxfordshire : logistics, economics, and social significance." Thesis, University of Oxford, 2018. http://ora.ox.ac.uk/objects/uuid:9208b07b-7c9d-447b-a2b1-26873f951018.

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Анотація:
Whilst Roman architecture has long stood as a discrete branch of classical studies, investigated for its artistic merit and cultural importance, the technical details of Roman construction have only recently started to receive considerable attention. This thesis contributes to a growing trend in Roman scholarship, that of the investigation of the processes, materials, and technologies behind the Roman built environment. The most prestigious buildings of the Empire often remain the focus of many of these studies, and so this thesis turns to explore the use of more everyday buildings and building materials, seeking a Romano-British vernacular, and investigating the processes of construction, building material production, and transport. It is argued, through using theoretical calculations of building material quantities, that even for relatively minor constructions, considerations of building material supply must have represented highly significant economic and logistical investment. To comprehend fully the subject it is asserted that building materials should not be treated, as they often are, as disparate artefacts, divided by substance into stone, ceramic, mortar, metal, etc., but rather they should be considered as related fragments of a building. They require synthetic analysis, through which a far truer understanding of the incredible effort involved in construction in the ancient world can be gained. The built environment of Roman Oxfordshire, and the Roman building material assemblage from Dorchester on Thames, are used as case studies. Primary analysis of building materials is carried out using an integrated analytical approach, combining thin section petrography with scanning electron microscopy and energy dispersive x-ray analysis. The outcomes of these analyses are interpreted against a background of archaeological and historical evidence for construction and material supply, in both the Roman and later periods, in the region and beyond.
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Muradali, Sheri. "Invasion and migration of clusters in oral carcinomas within three-dimensional collagen matrices : the effects of blocking b1 and a2b1 integrin function." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=27382.

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Cellular adhesion interactions involved in invasion and migration are crucial to cancer metastasis. Neoplastic tissue explants were cultivated in three-dimensional collagen lattices and monitored for the detachment of coordinated locomoting tumor cell clusters. Blocking monoclonal antibody treatment (10ug/mL) against the $ beta sb1$ and $ alpha sb2 beta sb1$ integrin receptors on cluster surfaces allowed the functional evaluation of these receptors during metastatic invasion. Clusters in treated wells exhibited a loss in migratory persistence, reduction in cluster motility and a greater amount of "stops" during migration as compared to control wells for both anti-$ beta sb1$ and anti-$ alpha sb2 beta sb1$ respectively. These results suggest that $ beta sb1$ integrins, and more specifically, $ alpha sb2 beta sb1$ play a significant role in maintaining normal cell-cell and cell-matrix interactions during metastatic invasion. Preliminary investigations using the anti-cancer drug, Taxol, against clusters within collagen matrices revealed a significant decrease in the total distance traveled, average speed and persistence, implicating its efficiency against certain cancers. The use of 3-D collagen systems for cell communication studies on locomoting tumor cell clusters may reveal novel and potentially important mechanisms involved in metastatic invasion as well as facilitate future assessment of potential anti-neoplastic drugs.
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6

N-unkyer, Anglaaere Luke Cyprian. "Improving the sustainability of cocoa farms in Ghana through utilization of native forest trees in agroforestry systems." Thesis, Bangor University, 2005. https://research.bangor.ac.uk/portal/en/theses/improving-the-sustainability-of-cocoa-farms-in-ghana-through-utilization-of-native-forest-trees-in-agroforestry-systems(2db9c4a0-0a9c-4a66-a2b1-570ccecbf094).html.

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Анотація:
The study investigatedf armers' ecologicalk nowledgea nd managemenrte lating to cocoa aggroforestins the Atwima district of Ghana,w ith the view to selecting and developing the potential of native forest tree species for use as shade in multi-strata cocoa agroforestry systems. More specifically, the study investigate farmers' knowledge about the ecology and managemenot f multi-stratac ocoas ystems,w ith the view to identifying native forest tree species preferred by farmers as shade for cocoa. Based on this preliminary survey of fanner knowledge and preferences, eight indigenous forest tree speciesw ere selectedf or field screening. Field studies involved: (i) assessmenot f their natural distribution in different landuse systems, to determine natural regeneration potential; (ii) evaluation of their phenological patterns and light regimes under their canopies, with the view to determining their suitability for shade provision; (iii) evaluation of growth performance, when planted as shade on cocoa farms; (iv) determination of potential below-ground complementarity in resource use (particularly water) between planted shade and the cocoa, through evaluation of root competitivity indices for the planted species, as well as determination of water use by means of sap flow measurementT. he study also evaluatedm ethodso f seedp re-treatmentt o enhance germinationo f T. letraptera seedsw, hich usually take a long time to germinate. Farmers' knowledge on site selection for cocoa cultivation was based on soil types and biological indicators. Their description of soil types was based on soil texture and colour. Trees, shrubs, and herbaceous species are used as indicators of soil fertility status. Farmers identified over 50 forest tree species and their role in the cocoa farming system. In Eight of these were selected for screening on-farm and on-station. These included: Albizia adianthifolia, Entandrophragma angolense, Entandrophragma utile, Newbouldia laevis, Pericopsis elata, Terminalia ivorensis and Tetrapleura tetraptera. The natural distribution of these species in mature cocoa farms, fallow lands and natural forest was evaluated and their regeneration potential discussed. Results of phenolog&icIa l patterns and crown characteristicso f the shadet ree speciesa re presenteda nd discussedw ith regards to their temporal complementarity in light (PAR and Red/Far Red light) capture. Seed pre-treatment and vegetative propagation techniques for T. tetraptera were investigated, with results indicating a good potential for the use of locally grown Citrusjambhiri Lush. (rough lemon) juice for seed pre-treatment. Auxin (IBA) application on leafy stem cuttings, at concentrations of 0.2%, 0.4%, 0.8% and 1.6% produced good rooting responses, compared to a control (0%), with 0.4% producing the highest response. Growth performance of all the planted species was evaluated over a two-year period, while root structure of, and rates of water uptake by, E. angolense, T. ivorensis and T tetraptera, which appeared to be the most promising species in terms of initial growth performance on the field, were also investigated. The results showed that T ivorensis, which appeared to be more shallow rooting than the others at this age Q years), was drawing more water from the soil than the other two species while T. tetraptera, with its roots oriented more vertically, was using less water than the others. Above-ground biomass, carbon and nutrient content, as well as litterfall, decomposition and nutrient release patterns of a multi-strata cocoa-Gliricidia agroforest are also reported and discussed.
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7

Harrison, Nigel. "An exploration of stakeholder perceptions of academic dishonesty and approaches used to promote academic integrity in nursing students." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/an-exploration-of-stakeholder-perceptions-of-academic-dishonesty-and-approaches-used-to-promote-academic-integrity-in-nursing-students(3ba434dc-cc35-4c23-a2b1-c4a1a5c082fe).html.

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Анотація:
An increased number of investigations for academic dishonesty with nursing students was a catalyst for this research. The aim was to explore stakeholder perceptions of academic dishonesty and approaches used to promote academic integrity. Literature reviewed was largely anecdotal, focusing on accounts of incidents and concern over nurses’ fitness to practise, recognising a need to enhance understanding and strategic solutions. A single case study design was utilised, capturing views of expert witnesses, including nursing students, academic staff, practice mentors and administrative and support staff, using individual interviews and nominal groups. Documentary evidence of incidence occurring between 2004 and 2010 were also analysed. An integrated definition of Academic and Practice Misconduct specific to nursing was developed and a range of contributing factors influencing students identified. Incidence within the school was found to have gradually reduced, where collusion and plagiarism was found to be the most common types occurring; highest at academic level five and in essays. Almost half of academic staff had reported an alleged incident. A hierarchy of Academic and Practice Misconduct emerged, indicating a range of severity and degrees of deliberateness. A self-assessment tool has been developed to enable students to measure their level of risk of Academic and Practice Misconduct. Five themes emerged from thematic analysis of data on approaches used to promote academic integrity: devising strategies, policies and procedures; educating stakeholders; implementing holistic preventative processes and deterrents; detecting and managing alleged incidents; and on-going monitoring and enhancement. This was synthesised into a collaborative cycle with four phases for use by stakeholders, listing activities undertaken at course, school and university level and in practice settings. A self-assessment tool has been developed for academic staff to measure their level of involvement in promoting Academic and Practice Integrity. The concepts of risk and person centred approaches are utilised as theoretical frameworks to underpin the research findings. The study is presented as an integration of research, education and practice.
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Kamble, Ketaki. "Dissecting the role of Ataxin 2 Binding Protein 1 in sarcomeric protein stoichiometry and generation of muscle diversity in Drosophila melanogaster." Thesis, 2018. https://etd.iisc.ac.in/handle/2005/5418.

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Drosophila muscles are an excellent model to study muscle development, diversity and function. Drosophila muscles consist of two major types –1. Indirect Flight Muscles (IFM), that are fibrillar; as opposed to other tubular muscles of head, abdomen etc. Ataxin 2 Binding Protein 1 (A2BP1) is a regulator of splicing; it binds to cis-intronic element 5’-UGCAUG-3; and carries out exon skipping and/or retention during splicing. Disruption of A2BP1 function has been associated with muscle disorders - cardiac hypertrophy and facio-scapulo-humoral dystrophy. However, detailed mechanism/s by which A2BP1 contributes to muscle development and physiology is not known. This thesis titled, “Dissecting the role of Ataxin 2 Binding Protein 1 in sarcomeric protein stoichiometry and generation of muscle diversity in Drosophila melanogaster” documents studies revealing novel roles of A2BP1 in generation of muscle diversity its role in progression of muscle disease. Studies on the IFMs show that A2BP1 regulates stoichiometry of Sarcomeric proteins, TnI and Act88F, directly or via transcription factor, Mef2. A2BP1 also regulates fiber specific splicing of Troponin-I. The improper splicing and stoichiometric imbalance in A2BP1 knock-down condition leads to muscle hypercontraction phenotype in the IFMs. Further, A2BP1 is expressed more in tubular muscles. The relative levels of RNA binding proteins- Arrest and A2BP1 are crucial for generating muscle fiber specific isoform profiles. A2BP1 negatively regulates fibrillar fate promoting factors- Extradenticle, Spalt (major) and Arrest, known to be involved in generation of muscle diversity. Identification of fiber specific isoform of Mef2 undergoing A2BP1 dependent splicing explains maintenance of fiber specific sarcomeric protein stoichiometry. This study shows that A2BP1 is a key dissipater of muscle fiber type specific changes during development.
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Chiu, Sue-Jean, and 邱淑貞. "Hepatocyte growth factor up-regulates a2b1 integrin in MDCK cells: implications in tubulogenesis." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/20635386706295492306.

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Анотація:
碩士
國立成功大學
生理學研究所
88
It has been well established that hepatocyte growth factor (HGF) induces branching tubule formation of Madin-Darby canine kidney (MDCK) cells cultured in collagen gel. Tubulogenesis per se requires the involvement of cell proliferation, migration, focalization proteolysis, cell-cell interaction and differentiation. However, signaling pathways and proteins involved in HGF-induced tubulogenesis by MDCK cells have not been thoroughly studied. Because cell-matrix interactions played important roles in tubulogenesis, we analyzed whether HGF altered the expression of extracellular matrix receptor (a2, a3, b1, and avb3 integrin). We found that among those proteins examined a2b1 integrin levels were enhanced by HGF. HGF induced up-regulation of a2b1 integrin expression was mediated via up-regulation of a2 integrin mRNA expression. Cycloheximide blocked HGF-induced increase in a2 integrin mRNA expression. To understand the signaling pathways leading to HGF-induced increase in a2b1 integrin expression, PD98059 (MEK1 inhibitor), LY294002 (PI3-kinase inhibitor), and GF109203X (PKC inhibitor) were used. We found that PD98059 blocked HGF-induced increase in a2b1 integrin expression. Furthermore, 5E8 (specific anti-a2b1 integrin antibody) was employed to elucidate the potential role of HGF up-regulation of a2b1 integrin in branching morphogenesis. 5E8 did not alter HGF-induced scattering effects but disrupted HGF-induced branching tubulogenesis in collagen gel via inhibition of cell-cell interactions and growth. Taken together, HGF up-regulates a2b1 integrin expression via an indirect pathway and the results of which contribute to the regulation of cell-cell interactions and cell growth during branching morphogenesis in collagen gel.
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Yeh, Yi-June, and 葉儀君. "Discoidin domain receptor 1 inhibits collagen-induced cell spreading via suppression of Cdc42 activation mediated by a2b1 integrin." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/45338242530504156353.

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Анотація:
碩士
國立成功大學
生理學研究所
93
Discoidin domain receptor (DDR) is a receptor tyrosine kinase for collagen. We previously showed that over-expression of DDR1 in MDCK cells prevented cell spreading, whereas dominant negative DDR1 induced cell spreading on collagen gel-coated dish. Cell spreading is an important characteristic for cell migration, but the mechanism whereby DDR1-inhibited cell spreading is still unidentified. Cell spreading involves organization of actin cytoskeleton, which is mainly regulated by Rho family-GTPases. In order to examine whether Rho family-GTPases are involved in collagen gel-regulated cell spreading, we employed pull-down assay and transient transfection of constitutive active or dominant negative GTPases in MDCK cells and observed whether they could alter collagen-induced cell morphological changes. The results showed DDR1 decreased the activation of Rac1 and Cdc42, but had no effects on RhoA activity. Neither constitutive active nor dominant negative Rac1 could alter DDR1-inhibited cell spreading. However, constitutive active Cdc42 rescued the DDR1-inhibited cell spreading and dominant negative Cdc42 inhibited cell spreading in cells overexpressing dominant negative DDR1. These results indicate that DDR1-inhibited cell spreading is mediated by inactivation of Cdc42. With the use of 5E8, a potent a2b1 integrin blocking antibody, we found that collagen-induced activation of Cdc42 is mediated by a2b1 integrin. Furthermore, FRNK completely blocked collagen-induced decrease in Cdc42 activity, but DDR1 did not influence the phosphorylation levels of FAK. Taken together, DDR1 inhibits collagen-induced cell spreading by suppression of Cdc42 activation, which is mediated by a2b1 integrin through FAK.
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Книги з теми "A2BP1"

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(Auteur), aïa Grégoire, and Odile Thievenaz (Auteur). Grammaire progressive du francais - Niveau intermédiaire A2B1 - LIVRE - 4ème edition - 450 nouveaux tests. French and European Publications Inc, 2017.

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Thievenaz, Odile. Grammaire progressive du francais - Niveau intermédiaire A2B1 - Corrigés - 4ème edition - 450 nouveaux tests. French and European Publications Inc, 2017.

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3

Objetivo escolar DELE A2-B1 : preparación para el DELE A2B1 con soluciones y transcripciones. SGEL, 2016.

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Тези доповідей конференцій з теми "A2BP1"

1

Santos, Higor, and Carina Alves. "A2BP: A Method for Ambidextrous Analysis of Business Process." In 19th International Conference on Enterprise Information Systems. SCITEPRESS - Science and Technology Publications, 2017. http://dx.doi.org/10.5220/0006278702270238.

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2

Setyoko, Hari, Bambang Sukamto, Fajar Wahyono, and Lilik Krismiyanto. "Kecernaan Lemak Kasar dan Bobot Karkas Ayam Broiler Akibat Penambahan Ekstrak Buah Mengkudu (Morinda citrifolia L.) dan Lactobacillus acidophilus." In Kedaulatan Pangan Nasional Melalui Pengembangan Potensi Ternak Lokal di Era Kenormalan Baru. Animal Science : Polije Proceedings Series, 2020. http://dx.doi.org/10.25047/proc.anim.sci.2020.19.

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Анотація:
Penelitian ini bertujuan untuk mengetahui pengaruh penambahan kombinasi Ekstrak Buah Mengkudu (EBM) dan Lactobacillus acidophilus (LA) terhadap kecernaan lemak kasar, persentase lemak abdominal, dan bobot karkas ayam broiler. Rancangan penelitian yang digunakan adalah Rancangan Acak Lengkap (RAL) pola faktorial 3x3 dengan 9 perlakuan dan 3 ulangan (setiap unit percobaan berisi 7 ekor ayam broiler). Perlakuan yang diterapkan pada penelitian yaitu A1B1 = EBM 0,04% + LA 0%; A1B2 = EBM 0,04% + LA 0,6%; A1B3 = EBM 0,04% + LA 1,2%; A2B1 = EBM 0,08% + LA 0%; A2B2 = EBM 0,08% + LA 0,6%; A2B3 = EBM 0,08% + LA 1,2%; A3B1 = EBM 0,12% + LA 0%; A3B2 = EBM 0,12% + LA 0,6%; A3B3 = EBM 0,12% + LA 1,2%. Parameter yang diukur meliputi kecernaan lemak kasar, persentase lemak abdominal, dan bobot karkas ayam broiler. Hasil penelitian dianalisis ANOVA. Apabila terdapat perbedaan tingkat signifikansi maka dilakukan uji lanjut dengan Uji Jarak Berganda Duncan. Hasil menunjukkan bahwa penambahan kombinasi EBM dan LA berpengaruh nyata (p<0,05) terhadap kecernaan lemak kasar, persentase lemak abdominal, dan bobot karkas ayam broiler. Kesimpulan penelitian yaitu penambahan kombinasi ekstrak buah mengkudu pada taraf 0,12% dan Lactobacillus acidophilus 1,2% dapat meningkatkan kecernaan lemak kasar dan bobot karkas namun menurukan persentase lemak abdominal.
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